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- Benjamin Cravatt, Ph.D.Exit Disclaimer
- Title: Professor in the Department of Chemistry
- Institution: Scripps Research Institute
- Research: Many oncogenes code for proteins that lack chemical probes and are even considered undruggable. Cravatt hopes to characterize the functional relevance of protein targets in cancer and cancer-related immunology. He will use the activity-based protein profiling (ABPP) technology to discover chemical probes that perturb the function of genetically-defined human cancer targets, as well as produce advanced chemical libraries for ABPP to further increase the druggable fraction of the human cancer proteome, including E3 ligases for ligand-induced protein degradation and post-translationally modified forms of cancer-relevant proteins.
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