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Drugs Approved for Colon and Rectal Cancer

This page lists cancer drugs approved by the Food and Drug Administration (FDA) for colon and rectal cancer. The list includes generic and brand names. This page also lists common drug combinations used in colon and rectal cancer. The individual drugs in the combinations are FDA-approved. However, the drug combinations themselves usually are not approved, although they are widely used.

The drug names link to NCI's Cancer Drug Information summaries. There may be drugs used in colon cancer and rectal cancer that are not listed here.

Drugs Approved for Colon Cancer

Avastin (Bevacizumab)

Bevacizumab

Camptosar (Irinotecan Hydrochloride)

Capecitabine

Cetuximab

Cyramza (Ramucirumab)

Eloxatin (Oxaliplatin)

Erbitux (Cetuximab)

5-FU (Fluorouracil Injection)

Fluorouracil Injection

Ipilimumab

Irinotecan Hydrochloride

Keytruda (Pembrolizumab)

Leucovorin Calcium

Lonsurf (Trifluridine and Tipiracil Hydrochloride)

Mvasi (Bevacizumab)

Nivolumab

Opdivo (Nivolumab)

Oxaliplatin

Panitumumab

Pembrolizumab

Ramucirumab

Regorafenib

Stivarga (Regorafenib)

Trifluridine and Tipiracil Hydrochloride

Vectibix (Panitumumab)

Xeloda (Capecitabine)

Yervoy (Ipilimumab)

Zaltrap (Ziv-Aflibercept)

Ziv-Aflibercept

Drug Combinations Used in Colon Cancer

CAPOX

FOLFIRI

FOLFIRI-BEVACIZUMAB

FOLFIRI-CETUXIMAB

FOLFOX

FU-LV

XELIRI

XELOX

Drugs Approved for Rectal Cancer