Cishe-umdlavuza / ukwelashwa / ukuhlolwa kwemitholampilo / isifo / amathumbu-neuroendocrine-isimila-g1 / ukwelashwa

Ukwelashwa Kwezilingo Zomtholampilo We-Neuroendocrine Tumor G1

Ukuhlolwa kwemitholampilo kuyizifundo zocwaningo ezibandakanya abantu. Ukuhlolwa kwemitholampilo kulolu hlu kungokwelashwa kwamathumbu kwe-neuroendocrine tumor g1. Zonke izilingo ohlwini zisekelwa yi-NCI.

Imininingwane eyisisekelo ye-NCI mayelana nokuhlolwa komtholampilo ichaza izinhlobo nezigaba zezilingo nokuthi zenziwa kanjani. Ukuhlolwa komtholampilo kubheka izindlela ezintsha zokuvimbela, ukuthola, noma ukwelapha izifo. Ungahle uthande ukucabanga ngokubamba iqhaza esivivinyweni somtholampilo. Khuluma nodokotela wakho ngosizo lokunquma ukuthi ngabe kukulungele yini.

Izilingo 1-4 kwezingu-4

I-Cabozantinib S-malate ekwelapheni iziguli ezine-Neuroendocrine Tumors Phambilini Yaphathwa nge-Everolimus Esendaweni Ephakeme, yeMetastatic, noma Ayikwazi Ukususwa Ukuhlinzwa

Lesi sigaba sesigaba sesithathu sokuhlolwa kwesifundo se-cabozantinib S-malate ukubona ukuthi sisebenza kahle kanjani uma siqhathaniswa ne-placebo ekwelapheni iziguli ezinamathumba we-neuroendocrine aphethwe phambilini nge-everolimus esasakaze ezicutshini eziseduze noma kuma-lymph node, asabalala kwezinye izindawo emzimbeni, noma awakwazi asuswe ngokuhlinzwa. I-Cabozantinib S-malate iyisidakamizwa se-chemotherapy esaziwa njenge-tyrosine kinase inhibitor, futhi sibheke ngqo ama-tyrosine kinase receptors, okuthi uma evinjiwe, anciphise ukukhula kwesimila.

Indawo: izindawo ezingama-329

I-PEN-221 eSomatostatin Receptor 2 Eveza Umdlavuza Othuthukile Kubandakanya Umdlavuza We-Neuroendocrine Namaseli Amancane Amaphaphu

I-Protocol PEN-221-001 iyi-open-label, multicenter Phase 1 / 2a Study ehlola i-PEN-221 ezigulini ezine-SSTR2 ezwakalisa i-advanced gastroenteropancreatic (GEP) noma i-lung noma i-thymus noma ezinye izicubu ze-neuroendocrine noma umdlavuza omncane wamaphaphu wamangqamuzana noma i-cell enkulu neuroendocrine carcinoma wamaphaphu.

Indawo: izindawo ezingu-7

I-Ribociclib ne-Everolimus ekwelapheni iziguli ezinezifo ezithuthukile ze-Neuroendocrine Tumors ze-Foregut Origin

Lesi sigaba sesivivinyo sesi-II sihlola ukuthi i-ribociclib ne-everolimus zisebenza kahle kanjani ekwelapheni iziguli ezinezicubu ze-neuroendocrine ezahlukaniswe kahle zemvelaphi ye-foregut esabalele kwezinye izingxenye zomzimba futhi imvamisa ayinakulashwa noma ilawulwe ngokwelashwa. I-Ribociclib ne-everolimus zingamisa ukukhula kwamangqamuzana e-tumor ngokuvimba amanye ama-enzyme adingekayo ekukhuleni kwamaseli.

Indawo: izindawo ezi-5

I-Sapanisertib ekwelapheni iziguli ezine-Metastatic or Refractory Pancreatic Neuroendocrine Tumor Engasuswa Ngokuhlinzwa

Lesi sigaba sesivivinyo sesi-II sihlola ukuthi isebenza kanjani kahle i-sapanisertib ekwelapheni iziguli ezinesigaxa se-pancreatic neuroendocrine esisakazekele kwezinye izindawo emzimbeni (i-metastatic), ayiphenduli ekwelashweni (i-refractory), noma ayikwazi ukukhishwa ngokuhlinzwa. Izidakamizwa ezinjenge-sapanisertib zingamisa ukukhula noma zinciphise amangqamuzana e-tumor ngokuvimba amanye ama-enzyme adingekayo ekukhuleni kwamaseli.

Indawo: izindawo ezingama-379