Malunga-nomhlaza / unyango / iintlobo / ukufakelwa kwe-stem-cell

Ukutshintshwa kweeseli lesiqu kunyango lomhlaza

Ukufakelwa kweseli kwestem kunceda ukubuyisela iiseli ezinesiqu esenziwe egazini kubantu abaye babhujiswa lunyango oluthile lomhlaza.

Ukufakelwa kweeseli zestem ziinkqubo ezibuyisela iiseli ezinesiqu esenziwe egazini kubantu abaye babhujiswa ziidosi eziphezulu kakhulu zekhemotherapy okanye unyango lwemitha olusetyenziselwa ukunyanga umhlaza othile.

Iiseli zeziqu ezenza igazi zibalulekile kuba zikhula zibe ziindidi ezahlukeneyo zeeseli zegazi. Ezona ntlobo ziphambili zeeseli zegazi zezi:

• Iiseli ezimhlophe zegazi, eziyinxalenye yamajoni akho omzimba kwaye zinceda umzimba wakho ukuba ulwe nosulelo

• Iiseli ezibomvu zegazi, ezithwala ioksijini kuwo wonke umzimba wakho

• Iiplatelets, ezinceda i-clot yegazi

Ufuna zonke iintlobo ezintathu zeeseli zegazi ukuze ube sempilweni.

Iindidi zoTshintsho lweeSeli eziQhelekileyo

Ukufakelwa kweseli ye-stem, ufumana iiseli ezinempilo ezenziwe ngamagciwane ngenaliti emthanjeni wakho. Nje ukuba zingene kwigazi lakho, iiseli zeziqu ziya kumongo wethambo, apho zithatha indawo yeeseli ezatshatyalaliswa lunyango. Iiseli ezenza igazi ezisetyenziselwa ukufakelwa zinokuvela kumongo wethambo, kwigazi, okanye kwintambo. Ukutshintshwa kunokuba:

• I-Autologous, oko kuthetha ukuba iiseli zeziqu zivela kuwe, kwisigulana

• I-Allogeneic, okuthetha ukuba iiseli zeziqu zivela komnye umntu. Umnikeli usenokuba sisizalwane segazi kodwa angangomntu ongazalaniyo.

• I-Syngeneic, oko kuthetha ukuba iiseli zeziqu zivela kwiwele lakho elifanayo, ukuba unayo

Ukunciphisa iziphumo ebezingalindelekanga ezinokubakho kunye nokuphucula amathuba okuba utyando lwe-allogeneic lusebenze, iiseli zeziqu ezakha igazi kufuneka zilingane nezakho ngeendlela ezithile. Ukuze ufunde okungakumbi malunga nendlela iiseli ezenza igazi ezihambelana ngayo, jonga ukufakelwa kwegazi kwiStem Cell.

Zisebenza njani iiStrim Cell Transplants against Cancer

Ukufakelwa kwe-stem cell akusebenzi ngokuchasene nomhlaza ngokuthe ngqo. Endaweni yoko, ziyakunceda uphinde ubenakho ukuvelisa iiseli ezinesiqu emva konyango ngeedosi eziphezulu kakhulu zonyango lwe-radiation, ichemotherapy, okanye zombini.

Nangona kunjalo, kwi-myeloma emininzi kunye nezinye iintlobo ze-leukemia, ukufakelwa kweseli ye-stem kunokusebenza ngokuchasene nomhlaza ngokuthe ngqo. Oku kwenzeka ngenxa yesiphumo esibizwa ngokuba yi-graft-versus-tumor enokuthi yenzeke emva kokutshintshwa kwe-allogeneic. I-Graft-versus-tumor iyenzeka xa iiseli ezimhlophe zegazi ezivela kumnikeli wakho (i-graft) zihlasela naziphi na iiseli zomhlaza ezihlala emzimbeni wakho (ithumba) emva konyango lwedosi ephezulu. Esi siphumo siphucula impumelelo kunyango.

Ngubani ofumana ukuTshintshelwa kweSeli esiStem

Ukufakelwa kweseli kwistem zihlala zisetyenziselwa ukunceda abantu abane-leukemia kunye ne-lymphoma. Zingasetyenziselwa i-neuroblastoma kunye ne-myeloma eninzi.

Ukufakelwa kweeseli kwestem kwezinye iintlobo zomhlaza kufundwa kwizilingo zeklinikhi, ezizizifundo zophando ezibandakanya abantu. Ukufumana isifundo esinokukhetha kuwe, jonga Fumana uVavanyo lweKlinikhi.

Ukutshintshwa kweseli kwestem kunokubangela iziphumo ebezingalindelekanga

Unyango oluphezulu lonyango lomhlaza onalo ngaphambi kokufakelwa kweseli enokubangela iingxaki ezinjengokopha kunye nomngcipheko owandayo wosulelo. Thetha nogqirha wakho okanye umongikazi malunga nezinye iziphumo ebezingalindelekanga onokuba nazo nokuba zinokuba mbi kangakanani. Ngolwazi oluthe kratya malunga neziphumo ebezingalindelekanga kunye nendlela yokulawula, jonga icandelo leziphumo ebezingalindelekanga.

Ukuba unokufakelwa kwe-allogeneic, unokuba nengxaki enkulu ebizwa ngokuba yi-graft-versus-host host. Isifo esixhonyiweyo xa kuthelekiswa nomsingathi sinokubakho xa iiseli ezimhlophe zegazi ezivela kumnikeli wakho (ufakelo) ziqonda iiseli emzimbeni wakho (umgcini) njengezangaphandle kwaye zibahlasele. Le ngxaki inokubangela ukonakala kulusu lwakho, isibindi, amathumbu kunye namanye amalungu amaninzi. Inokwenzeka kwiiveki ezimbalwa emva kokufakelwa okanye kamva kamva. Isifo sokuthintela ukunganyangeki sinokunyangwa nge-steroids okanye ezinye iziyobisi ezikhusela amajoni akho omzimba.

Ukusondela kwegazi elenza igazi elenza ukuba lihambelane nelakho, mancinci amathuba okuba ube nakho ukumiliselwa ngokuchaseneyo nesifo. Ugqirha wakho unokuzama ukukhusela ngokukunika amayeza okucinezela amajoni akho omzimba.

Zingaphi iindleko zokuTshintshelwa kweeseli eziQhelekileyo

Ukufakelwa kweeseli zeziqu ziinkqubo ezinzima ezibiza kakhulu. Uninzi lwezicwangciso zeinshurensi zigubungela ezinye zeendleko zokufakwa kwezinye iintlobo zomhlaza. Thetha ngesicwangciso sakho sezempilo malunga nokuba zeziphi iinkonzo eziza kuzihlawulela. Ukuthetha neofisi yeshishini apho uya khona kunokukunceda ukuba uziqonde zonke iindleko ezichaphazelekayo.

Ukufunda ngamaqela anokukwazi ukubonelela ngoncedo lwezezimali, yiya kwiziko ledatha leCancer National, Imibutho ebonelela ngeenkonzo zeNkxaso kwaye ukhangele "uncedo lwezemali." Okanye tsalela umnxeba mahala 1-800-4-CANCER (1-800-422-6237) ngolwazi malunga namaqela anokukwazi ukunceda.

Yintoni omele uyilindele xa ufumana ukufakelwa kweSeli yeStem

Apho Uya khona ngokuTshintshelwa kweSeli yeStem

Xa ufuna ukufakelwa kwe-cell allogeneic, kuyakufuneka uye esibhedlele esineziko elikhethekileyo lokufakelwa. Inkqubo yeSizwe yoMnikeli weMarrow igcina uluhlu lwamaziko okufakelwa e-United StatesKhupha i-Disclaimer enokukunceda ufumane iziko lokufakelwa.

Ngaphandle kokuba uhlala kufutshane neziko lokufakelwa, kungafuneka uhambe usiya ekhaya ukunyanga. Kuya kufuneka uhlale esibhedlele ngexesha lofakelo lwakho, unokuba nakho ukuba ngumguli ongalaliswayo, okanye kungafuneka ubesesibhedlele kuphela ixesha lexesha. Xa ungekho esibhedlele, kuya kufuneka uhlale ehotele okanye kwigumbi elikufutshane. Amaziko amaninzi okufakelwa anokunceda ekufumaneni izindlu ezikufuphi.

Kuthatha ixesha elingakanani ukuba nokuTshintshwa kweSeli yeStem

Ukufakelwa kweseli kwistem kungathatha iinyanga ezimbalwa ukugqiba. Inkqubo iqala ngonyango lwamayeza aphezulu e-chemotherapy, unyango ngemitha, okanye indibaniselwano yezi zimbini. Olu nyango luqhubeka iveki okanye ezimbini. Nje ukuba ugqibile, uya kuba neentsuku ezimbalwa zokuphumla.

Okulandelayo, uya kufumana iiseli ezinesiqu ezenza igazi. Iiseli zeziqu ziya kunikwa kuwe ngokusebenzisa ipayipi ye-IV. Le nkqubo ifana nokutofelwa igazi. Kuthatha iiyure ezi-1 ukuya kwezi-5 ukufumana zonke iiseli zeziqu.

Emva kokufumana iiseli zeziqu, uqala isigaba sokubuyisela. Ngeli xesha, ulinde iiseli zegazi ozifumeneyo ukuqala ukwenza iiseli ezintsha zegazi.

Kwanasemva kokuba ubalo lwegazi lwakho lubuyela esiqhelweni, kuthatha ixesha elide ukuba amajoni akho omzimba abuyele ngokupheleleyo-iinyanga ezininzi zokufakelwa kwe-autologous kunye ne-1 ukuya kwi-2 iminyaka yokufakelwa kweallogeneic okanye i-syngeneic.

Ukutshintshwa kweeseli zestem kunokukuchaphazela njani

Ukufakelwa kweseli kwistem kuchaphazela abantu ngeendlela ezahlukeneyo. Indlela oziva ngayo ixhomekeke:

• Uhlobo lofakelo onalo

• Amayeza onyango owawunawo ngaphambi kokufakelwa

• Uphendula njani kunyango lwedosi ephezulu

• Uhlobo lwakho lomhlaza

• Uhambele phambili kangakanani umhlaza wakho

• Ubusempilweni kangakanani ngaphambi kokufakelwa

Kuba abantu baphendula ukufakelwa kweeseli ngeendlela ezahlukeneyo, ugqirha wakho okanye abongikazi abanakho ukwazi ngokuqinisekileyo ukuba le nkqubo iya kukwenza uzive njani.

Indlela yokuxelela ukuba iStem Cell Transplant iyasebenza

Oogqirha baya kulandela inkqubela yeeseli ezintsha zegazi ngokujonga ukubalwa kwegazi rhoqo. Njengoko iiseli zeziqu ezisandula ukufakelwa ngokutsha zivelisa iiseli zegazi, ubalo lwegazi lakho luya kunyuka.

Ukutya okukhethekileyo

Unyango lwedosi ephezulu onayo ngaphambi kokufakelwa kweseli ye-stem kunokubangela iziphumo ebezingalindelekanga ezenza kube nzima ukutya, ezinje ngezilonda zomlomo kunye nesicanucanu. Xelela ugqirha wakho okanye unesi ukuba unengxaki yokutya ngelixa ufumana unyango. Unokufumana ukuba luncedo ukuthetha nengcali yokutya. Ngolwazi oluthe kratya malunga nokuhlangabezana neengxaki zokutya jonga incwadana ethi Amacebo okutya okanye icandelo leziphumo ebezingalindelekanga.

Ukusebenza ngexesha lokuTshintshela kweSeli yakho yoBume

Nokuba ungasebenza okanye ungasebenzi ngexesha lokufakelwa kweseli ye-stem kunokuxhomekeka kuhlobo lomsebenzi onawo. Inkqubo yokufakelwa kweseli ye-stem, kunye nonyango lweedosi eziphezulu, ukufakelwa, kunye nokubuyisela kwimeko yesiqhelo, kunokuthatha iiveki okanye iinyanga. Uya kungena uphuma esibhedlele ngeli xesha. Nokuba awukho esibhedlele, ngamanye amaxesha kuyakufuneka uhlale kufutshane nayo, kunokuba uhlale ekhayeni lakho. Ke, ukuba umsebenzi wakho uyakuvumela, unokufuna ukwenza amalungiselelo okuba usebenze ngokude ube nesingxungxo.

Abaqeshi abaninzi bayacelwa ngumthetho ukuba batshintshe ishedyuli yomsebenzi wakho ukuhlangabezana neemfuno zakho ngexesha lonyango lomhlaza. Thetha nomqeshi wakho malunga neendlela zokuhlengahlengisa umsebenzi wakho ngexesha lonyango. Unokufunda ngakumbi ngale mithetho ngokuthetha nonontlalontle.