Types/uterine/patient/endometrial-treatment-pdq

Endometrial Kenza Kurapa (®) -Patient Shanduro

Ruzivo Ruzhinji Nezve Endometrial Kenza

PFUNGWA DZINOKOSHA

• Kenza yeEndometrial chirwere umo maronda (gomarara) maseru anoumba mumatumbu eendometrium.

• Kufutisa uye kuve nemetabolic syndrome kunogona kuwedzera njodzi yekenza yemendometri.

• Kutora tamoxifen yekenza yemazamu kana kutora estrogen yoga (isina progesterone) kunogona kuwedzera njodzi yekenza yemendometri.

• Zviratidzo nezviratidzo zvegomarara remendometri zvinosanganisira kubuda kweropa kusangana nekutsi kwemukadzi kana kurwadziwa muchiuno.

• Kuyedza kunoongorora endometrium kunoshandiswa kuona (kuwana) uye kuongorora cancer yegomarara.

• Zvimwe zvinhu zvinokanganisa kufungidzira (mukana wekupora) uye sarudzo dzekurapa.

Kenza yeEndometrial chirwere umo maronda (gomarara) maseru anoumba mumatumbu eendometrium.

Iyo endometrium ndiyo yakatarwa yechibereko, isina mhango, yemhasuru nhengo mubeche remukadzi. Chibereko ndipo panokura chibereko. Mune vakadzi vazhinji vasina nhumbu, chibereko chinenge chakareba 3 inches. Iyo yepazasi, yakatetepa yekupedzisira yechibereko ndicho chibereko chechibereko, chinotungamira kuchikadzi.

Anatomy yevakadzi yekubereka system. Nhengo dziri muchikamu chekubereka chevakadzi dzinosanganisira chibereko, mazai, mazamu, mazamu, uye mukadzi. Chibereko chine mhasuru yekunze inoshevedza inonzi myometrium uye nekamuri yemukati inonzi endometrium.

Cancer ye endometrium yakasiyana nekenza yemhasuru yechibereko, iyo inonzi sarcoma yechibereko. Ona pfupiso yePDPQ paUterine Sarcoma Kurapa kuti uwane rumwe ruzivo nezve uterine sarcoma.

Kufutisa uye kuve nemetabolic syndrome kunogona kuwedzera njodzi yekenza yemendometri.

Chero chipi zvacho chinowedzera mukana wako wekutora chirwere chinonzi njodzi chinhu. Kuva nenjodzi hazvireve kuti uchawana gomarara; kusava nenjodzi hazvireve kuti hauzobatwe negomarara. Taura nachiremba wako kana iwe uchifunga kuti ungave uri panjodzi yekenza yemagetsi.

Njodzi dzinokonzera kenza yemendometri dzinosanganisira zvinotevera:

• Kutora estrogen-chete hormone kutsiva therapy (HRT) mushure mekuguma kuenda kumwedzi.

• Kutora tamoxifen kudzivirira kana kurapa kenza yemazamu.

• Kufutisa.

• Kuva nechirwere chemagetsi.

• Kuve nerudzi rwechipiri chirwere cheshuga.

• Kuratidzwa kwemaseru endometrius kune estrogen yakaitwa nemuviri. Izvi zvinogona kukonzerwa ne:

• Kusambozvara.

• Kutevera kumucheche.

• Kutanga kuenda kumwedzi panguva inotevera.

• Kuve ne polycystic ovarian syndrome.

• Kuva nenhoroondo yemhuri yekenza yemendometri mune yekutanga-degree hama (amai, hanzvadzi, kana mwanasikana).

• Kuve nehumwe hunhu mamiriro, senge Lynch syndrome.

• Kuve ne endometrial hyperplasia.

Kukwegura ndiyo njodzi huru kune vakawanda kanzira. Mukana wekubata cancer unowedzera paunenge uchikura.

Kutora tamoxifen yekenza yemazamu kana kutora estrogen yoga (isina progesterone) kunogona kuwedzera njodzi yekenza yemendometri.

Endometrial kenza inogona kukura mukenza yemazamu varwere vakamborapwa netamoxifen. Murwere anotora chinodhaka ichi uye ane kubuda kweropa kusangana nekutsi kwemukadzi anofanira kuva nemubvunzo wekutevera uye bhaisikopo remberi kwemendometri kana zvichidikanwa. Vakadzi vanotora estrogen (hormone inokanganisa kukura kweimwe gomarara) voga vane njodzi yakawandisa yekenza yemendometri. Kutora estrogen yakabatana neprogesterone (imwe hormone) hakuwedzeri njodzi yemukadzi yekenza yemendometri.

Zviratidzo nezviratidzo zvegomarara remendometri zvinosanganisira kubuda kweropa kusangana nekutsi kwemukadzi kana kurwadziwa muchiuno.

Izvi nezvimwe zviratidzo uye zviratidzo zvinogona kukonzerwa nekenza yemendometri kana nemamwe mamiriro. Tarisa nachiremba wako kana iwe uine chero chinotevera:

• Kubuda ropa kumunhukadzi kana kubuda kubuda zvisina hukama nekuenda kumwedzi (nguva).

• Vaginal kubuda ropa mushure mekuguma kuenda kumwedzi.

• Zvakaoma kana zvinorwadza kuita weti.

• Marwadzo panguva yepabonde.

• Marwadzo munzvimbo yepelvic.

Kuyedza kunoongorora endometrium kunoshandiswa kuona (kuwana) uye kuongorora cancer yegomarara.

Nekuti kenza yemendometriya inotangira mukati mechibereko, haiwanzo kuratidza mumhedzisiro yePap test. Nechikonzero ichi, muyenzaniso wetissue endometrial unofanirwa kubviswa uye kuongororwa pasi pe microscope kutsvaga maseru ekenza. Imwe yemaitiro anotevera anogona kushandiswa:

• Endometrial biopsy: Kubviswa kwetishu kubva muendometrium (mukati memukati wechibereko) nekuisa mutete, unopfava chubhu kuburikidza nemuromo wechibereko uye muchibereko. Iyo chubhu inoshandiswa kupuruzira zvinyoro zvishoma chidiki chemucheka kubva ku endometrium uye wozobvisa iwo masampuli esuru. Nyanzvi yezvirwere anoona tishu pasi pe microscope kutsvaga maseru ekenza.

• Dilatation uye curettage: Maitiro ekubvisa sampuli yetishu kubva mukati memukati wechibereko. Muromo wechibereko unodhonzwa uye mushonga (chipenga chakaita kunge chipunu) chinoiswa muchibereko kubvisa nyama. Iwo maturu sampuli anotariswa pasi pe microscope kune zviratidzo zvechirwere. Maitiro aya anonziwo D&Z.

Dilatation uye curettage (D uye C). A speculum inoiswa mukati memukadzi kuti ikure kuti utarise pamuromo wechibereko (pekutanga jira). A dilator inoshandiswa kuwedzera muromo wechibereko (wepakati pepaneru). Mushonga unoiswa kuburikidza nemuromo wechibereko muchibereko kuti ubvise zvisizvo zvisina kujairika (yekupedzisira pani).

• Hysteroscopy: Maitiro ekutarisa mukati mechibereko munzvimbo dzisina kujairika. Hysteroscope inoiswa kuburikidza nemukadzi uye chibereko muchibereko. Iyo hysteroscope chishoma, chubhu-senge chiridzwa chine mwenje uye lens yekuona. Iyo inogona zvakare kuve nechishandiso chekubvisa matissue sampuli, ayo anoongororwa pasi pe microscope yezviratidzo zvegomarara.

Mimwe bvunzo uye maitiro anoshandiswa kuongorora cancer yekemometri anosanganisira anotevera:

• Kuongorora kwepanyama uye nhoroondo: Kuongororwa kwemuviri kutarisa zviratidzo zvehutano, kusanganisira kuongorora zviratidzo zvehosha, zvakadai semapundu kana chero chinhu chinoratidzika sechisina kujairika. Nhoroondo yemaitiro ehutano hwemurwere uye kurwara kwakapfuura uye kurapwa kuchatorwawo.

• Transvaginal ultrasound bvunzo: Maitiro anoshandiswa kuongorora mukadzi, chibereko, fallopian machubhu, uye bladder. An ultrasound transducer (probe) inoiswa mukati memukadzi uye inoshandiswa kudzora mafungu ane simba-ruzha (ultrasound) kubva munyama dzemukati kana mitezo uye kuita maungira. Maungira anoumba mufananidzo wemuviri munyama unonzi sonogram. Chiremba anogona kuona mamota nekutarisa kune sonogram.

Transvaginal ultrasound. An ultrasound probe yakabatana nekombuta inoiswa mukati memukadzi uye inofambiswa zvinyoro kuratidza nhengo dzakasiyana. Iyo probe inoburitsa mafungu eruzha kubva mukati memukati uye matishu kuti aite maungira anoita iyo sonogram (komputa pikicha).

Zvimwe zvinhu zvinokanganisa kufungidzira (mukana wekupora) uye sarudzo dzekurapa.

Kufungidzira (mukana wekupora) uye sarudzo dzekurapa dzinoenderana nezvinotevera:

• Chikamu chegomarara (kunyangwe chiri mu endometrium chete, chinosanganisira chiberekero chemadziro, kana chakapararira kune dzimwe nzvimbo mumuviri).

• Iko maseru ekenza anotaridzika pasi pe microscope.

• Kunyangwe maseru egomarara akanganiswa neprogesterone.

Kenza yeEndometriya inogona kurapwa nekuti inowanzoonekwa ichangotanga.

Zvimwe zvinhu zvinokanganisa kufungidzira (mukana wekupora) uye sarudzo dzekurapa.

Kufungidzira (mukana wekupora) uye sarudzo dzekurapa dzinoenderana nezvinotevera:

• Chikamu chegomarara (kunyangwe chiri mu endometrium chete, chinosanganisira chiberekero chemadziro, kana chakapararira kune dzimwe nzvimbo mumuviri).

• Iko maseru ekenza anotaridzika pasi pe microscope.

• Kunyangwe maseru egomarara akanganiswa neprogesterone.

Kenza yeEndometriya inogona kurapwa nekuti inowanzoonekwa ichangotanga.

Matanho eEndometrial Cancer

PFUNGWA DZINOKOSHA

• Mushure mekunge gomarara remendometri raonekwa, kuongororwa kunoitwa kuti uone kana masero ekenza apararira mukati mechibereko kana kune zvimwe zvikamu zvemuviri.

• Pane nzira nhatu dzinopararira negomarara mumuviri.

• Gomarara rinogona kutapukira kubva kwarakatanga kuenda kune dzimwe nhengo dzemuviri.

• Aya anotevera matanho anoshandiswa kune endometrial cancer.

• Chikamu I

• Chikamu II

• Chikamu chechitatu

• Chikamu IV

• Kenza yeEndometrial inogona kuve yakarongedzwa kurapwa seinotevera:

• Kenza yakadzika-panjodzi endometrial

• Kenza ine njodzi yepamusoro-soro

Mushure mekunge gomarara remendometri raonekwa, kuongororwa kunoitwa kuti uone kana masero ekenza apararira mukati mechibereko kana kune zvimwe zvikamu zvemuviri.

Maitiro anoshandiswa kutsvaga kana gomarara rapararira mukati mechibereko kana kune mamwe mativi emuviri anonzi staging. Ruzivo rwakaunganidzwa kubva munzira yekugadzwa rinotara danho rechirwere. Izvo zvakakosha kuti uzive nhanho kuitira kuronga kurapwa. Mimwe bvunzo nemaitiro zvinoshandiswa mukugadzirisa matanho. Hysterectomy (kuvhiya uko chibereko chinobviswa) kunowanzoitwa kurapa kenza yemendometri. Masampuli enyama anotorwa kubva munzvimbo yakatenderedza chibereko uye otariswa pasi pe microscope kuti aone zviratidzo zvecancer kubatsira kuziva kuti gomarara rapararira here.

Maitiro anotevera anogona kushandiswa mukugadzirisa matanho:

• Pelvic bvunzo: Kuongororwa kwemukadzi, chibereko, chibereko, fallopian machubhu, ovari, uye rectum. A speculum inowanikwa mukati memukadzi uye chiremba kana mukoti anotarisa kumukadzi nemuromo wechibereko kune zviratidzo zvehosha. Kuedzwa kwePap kwechibereko chechibereko kunowanzoitwa. Chiremba kana mukoti vanoisawo rimwe kana maviri akazorwa mafuta, zvigunwe zvakaiswa ruoko rweumwe ruoko mukati memukadzi uye anoisa rumwe ruoko pamusoro pezasi peguvhu kuti unzwe kukura, chimiro, uye chinzvimbo chechibereko nemazai. Chiremba kana mukoti anoisawo chigunwe chakazorwa mafuta, chakapfekerwa muguruva kuti unzwe mabundu kana nzvimbo dzisina kujairika.

Kuongorora kwepelvic. Chiremba kana mukoti vanoisa imwe kana miviri yakazorwa mafuta, zvigunwe zvakaiswa ruoko rweumwe ruoko mukati memukadzi uye kutsikirira padumbu rezasi nerumwe ruoko. Izvi zvinoitwa kuti unzwe kukura, chimiro, uye chinzvimbo chechibereko nemazai. Iyo vagina, cervix, fallopian machubhu, uye rectum inoongororwawo.

• Chest x-ray: X-ray yenhengo nemapfupa mukati mechipfuva. X-ray imhando yesimba remagetsi rinogona kupfuura nemuviri uye kupinda mufirimu, richiita mufananidzo wenzvimbo dziri mukati memuviri.

• CT scan (CAT scan): Maitiro anoita akateedzana emifananidzo yakajeka yenzvimbo dziri mukati memuviri, inotorwa kubva kumakona akasiyana. Mifananidzo yacho inogadzirwa nekombuta yakabatana neiyo x-ray muchina. Dhayi inogona kuiswa jekiseni kana kumedzwa kubatsira nhengo kana zvinyama kuratidza zvakajeka. Iyi nzira inonziwo computed tomography, computerized tomography, kana komputa axial tomography.

• MRI (magnetic resonance imaging): Maitiro anoshandisa magineti, masaisai eredhiyo, uye komputa kugadzira yakateedzana mifananidzo yakajeka yenzvimbo dziri mukati memuviri. Iyi nzira inonziwo nyukireya magnetic resonance imaging (NMRI).

• PET scan (positron emission tomography scan): Iyo nzira yekuwana yakaipa malonda maseru mumuviri. Chishoma che radioactive glucose (shuga) inoiswa mutsinga. Iyo PET scanner inotenderera yakatenderedza muviri uye inogadzira mufananidzo wepo glucose iri kushandiswa mumuviri. Malignant tumarara maseru anoratidza kupenya mumufananidzo nekuti anoshanda uye anotora glucose yakawanda kupfuura zvinoita maseru akajairwa.

• Lymph node dissection: Maitiro ekuvhiya ayo ma lymph node anobviswa munzvimbo yepelvic uye sampuro yetishu inotariswa pasi pe microscope yezviratidzo zvegomarara. Iyi nzira inonziwo lymphadenectomy.

Pane nzira nhatu dzinopararira negomarara mumuviri.

Kenza inogona kupararira kuburikidza nematinji, iyo lymph system, uye neropa:

• Tishu. Kenza inopararira kubva kwayakatanga nekukura ichipinda munzvimbo dziri pedyo.

• Lymph maitiro. Kenza inopararira kubva kwayakatanga nekupinda muiyo lymph system. Kenza inofamba nemumidziyo yema lymph ichienda kune dzimwe nhengo dzemuviri.

• Ropa. Kenza inopararira kubva payakatanga nekupinda muropa. Kenza inofamba nemidzi yeropa ichienda kune dzimwe nhengo dzemuviri.

Gomarara rinogona kutapukira kubva kwarakatanga kuenda kune dzimwe nhengo dzemuviri.

Kana kenza ikapararira kune chimwe chikamu chemuviri, inonzi metastasis. Cancer maseru anotsemuka kubva kwaakatanga (iro bundu rekutanga) uye achifamba kuburikidza neye lymph system kana ropa.

• Lymph maitiro. Gomarara rinopinda mu "lymph system", rinofamba nemumidziyo ye "lymph", uye rinogadzira bundu (metastatic tumor) mune chimwe chikamu chemuviri.

• Ropa. Kenza inopinda muropa, inofamba nemutsinga dzeropa, yoita bundu (metastatic tumor) mune chimwe chikamu chemuviri.

Iyo metastatic bundu irwo rudzi rwecancer seyakanyanya bundu. Semuenzaniso, kana kenza yemendometriya ichipararira mumapapu, masero emukenza mumapapu ndiwo masero emukenza eendometrial. Hosha iyi metastatic endometrial cancer, kwete cancer yemukenza.

Aya anotevera matanho anoshandiswa kune endometrial cancer.

Chikamu I

Chikamu IA uye nhanho IB endometrial kenza. Muchikamu IA, kenza iri mu endometrium chete kana pasi pehafu nepakati peiyo myometrium (iyo mhasuru yakatenderera yechibereko). Muchikamu IB, kenza yakapararira hafu kana kupfuura mu myometrium.

Padanho I, gomarara rinowanikwa muchibereko chete. Chikamu I chakakamurwa muzvikamu IA uye IB, zvichibva nekuti gomarara rapararira zvakadii.

• Chikamu IA: Kenza iri mu endometrium chete kana pasi pehafu nepakati peiyo myometrium (tsandanyama dumbu rechibereko).

• Chikamu IB: Cancer yakapararira hafu kana kupfuura mu myometrium.

Chikamu II

Chikamu chechipiri che endometrial kenza. Gomarara rapararira mumuviri wechibereko, asi harina kupararira kunze kwechibereko.

Muchikamu chechipiri, gomarara rapararira mumuviri wechibereko, asi harina kupararira kunze kwechibereko.

Chikamu chechitatu

Muchikamu chechitatu, gomarara rapararira kupfuura chibereko nemuromo wechibereko, asi harina kupararira kupfuura chiuno. Chikamu chechitatu chakakamurwa muzvikamu IIIA, IIIB, uye IIIC, zvichibva nekuti kenza yapararira zvakadii mukati mehudyu.

• Stage IIIA: Kenza yakapararira kune yekunze chikamu chechibereko uye / kana kune echipfuva machubhu, mazai, uye mitsipa yechibereko

Chikamu IIIA endometrial cancer. Gomarara rapararira kune dumbu rekunze kwechibereko uye / kana kumatumbu, mazai, kana mitsipa yechibereko.

• Stage IIIB: Kenza yakapararira kumunhukadzi uye / kana kune parametrium (inosangana nyama uye mafuta akatenderedza chibereko).

Stage IIIB endometrial kenza. Gomarara rapararira kunhengo yemukadzi uye / kana kune parametrium (inosanganisa nyama nemafuta zvakakomberedza chibereko nemuromo wechibereko).

• Stage IIIC: Kenza yakapararira kune lymph node mumapapiro uye / kana kutenderedza aorta (arteri yakakura mumuviri, inotakura ropa kure nemoyo).

Chikamu IIIC endometrial cancer. Gomarara rapararira kuma lymph node mumapfupa uye / kana kutenderedza aorta (tsinga hombe mumuviri, inotakura ropa kure nemoyo).

Chikamu IV

Muchikamu IV, gomarara rapararira kupfuura chiuno. Chikamu IV chakakamurwa muzvikamu IVA uye IVB, zvichibva nekuti gomarara rakapararira zvakadii.

• Stage IVA: Kenza yakapararira kune dundira uye / kana ura hwemadziro.

Chikamu cheIVA endometrial cancer. Gomarara rapararira mudundira uye / kana ura.

• Chikamu IVB: Kenza yakapararira kune zvimwe zvikamu zvemuviri kupfuura pechiuno, kusanganisira dumbu uye / kana lymph node mukati meguruva.

Chikamu IVB endometrial cancer. Gomarara rapararira kumativi emuviri kunze kwepachechi, senge dumbu uye / kana lymph node mune iyo groin.

Kenza yeEndometrial inogona kuve yakarongedzwa kurapwa seinotevera:

Kenza yakadzika-panjodzi endometrial

MaBanga 1 ne2 mamota anowanzo kutaridzika kunge ane njodzi shoma. Kazhinji hazvipararire kune dzimwe nhengo dzomuviri.

Kenza ine njodzi yepamusoro-soro

Giredhi 3 mamota anoonekwa seakanyanya njodzi. Vanowanzopararira kune dzimwe nhengo dzomuviri. Uterine papillary serous, yakajeka sero, uye carcinosarcoma ndiwo matatu madiki ekenza yemendometri ayo anoonekwa segiredhi 3.

Kakawanda Endometrial Cancer

Kazhinji kenza yemendometrial igomarara rakadzokazve (kudzoka) mushure mekurapwa. Kenza inogona kudzoka muchibereko, muchiuno, mune lymph node mudumbu, kana mune mamwe mativi emuviri

Kurapa Sarudzo Kuongorora

PFUNGWA DZINOKOSHA

• Kune akasiyana marudzi ekurapa kwevarwere vane endometrial cancer.

• Mhando shanu dzekurapwa kwakajairika dzinoshandiswa:

• Kuvhiya

• Radiation kurapa

• Chemotherapy

• Hormone kurapa

• Targeted kurapwa

• Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

• Kurapa kwekenza yemendometriya kunogona kukonzera mhedzisiro.

• Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

• Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kenza kurapwa.

• Yekutevera-bvunzo inogona kudikanwa.

Kune akasiyana marudzi ekurapa kwevarwere vane endometrial cancer.

Mhando dzakasiyana dzekurapa dziripo kune varwere vane gomarara remendometri. Mamwe marapirwo akajairwa (iko kurapwa kwazvino kwashandiswa), uye kumwe kuedzwa mumakiriniki ekuedzwa A kurapwa kiriniki kuyedzwa chidzidzo chekutsvaga chakaitirwa kubatsira kuvandudza marapirwo azvino kana kuwana ruzivo marapirwo matsva evarwere vane gomarara. Kana kiriniki miedzo ikaratidza kuti kurapwa kutsva kuri nani pane kwese kurapwa, kurapwa kutsva kunogona kuve kwakajairwa kurapwa. Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki. Mimwe miedzo yekiriniki yakavhurwa chete kune varwere vasina kutanga kurapwa.

Mhando shanu dzekurapwa kwakajairika dzinoshandiswa:

Kuvhiya

Kuvhiya (kubvisa kenza mukuvhiya) ndiyo inonyanya kurapa kenza yemendometri. Maitiro anotevera ekuvhiya anogona kushandiswa:

• Yese hysterectomy: Kuvhiya kubvisa chibereko, kusanganisira wechibereko. Kana chibereko nemuromo wechibereko zvakaburitswa kuburikidza nemukadzi, kuvhiya kunodaidzwa kunzi vaginal hysterectomy. Kana chibereko nemuromo wechibereko zvakaburitswa kuburikidza nekucheka kukuru (kucheka) mudumbu, kuvhiyiwa kunodaidzwa kunzi kusununguka kwemudumbu. Kana chibereko nemuromo wechibereko zvakaburitswa kuburikidza nekakuchekwa kadiki (kucheka) mudumbu uchishandisa laparoscope, kuvhiya kunodaidzwa kunzi laparoscopic hysterectomy.

Hysterectomy. Chibereko chinobviswa nekuvhiya pamwe kana pasina dzimwe nhengo kana nyama. Mune yakazara hysterectomy, chibereko uye chibereko zvinobviswa. Mune yakazara hysterectomy ine salpingo-oophorectomy, (a) chibereko pamwe neumwe (unilateral) ovary uye fallopian tube zvinobviswa; kana (b) chibereko pamwe nezvose (zviviri) mazai uye mazamu (fallopian tubes) anobviswa. Mune radical hysterectomy, chibereko, cervix, ese mavari, ese fallopian machubhu, uye padyo tishu zvinobviswa. Maitiro aya anoitwa uchishandisa yakaderera transverse incision kana yakatwasuka incision.

• Bilateral salpingo-oophorectomy: Kuvhiya kubvisa ese maovari uye ese ari maviri fallopian machubhu.

• Radical hysterectomy: Kuvhiya kubvisa chibereko, cervix, uye chikamu chemukadzi. Mazai ovari, fallopian machubhu, kana ma lymph node ari padyo anogona zvakare kubviswa.

• Lymph node dissection: Maitiro ekuvhiya ayo ma lymph node anobviswa munzvimbo yepelvic uye sampuro yetishu inotariswa pasi pe microscope yezviratidzo zvecancer. Iyi nzira inonziwo lymphadenectomy.

Mushure mekunge chiremba abvisa kenza yese inoonekwa panguva yekuvhiyiwa, vamwe varwere vanogona kupihwa radiation radiation kana kurapwa kwehomoni mushure mekuvhiyiwa kuuraya chero gomarara maseru akasara. Mushonga wakapihwa mushure mekuvhiyiwa, kudzikisa njodzi yekuti gomarara richadzoka, inonzi adjuvant therapy.

Radiation kurapa

Radiation kurapa kurapwa kenza iyo inoshandisa yakakwira-simba x-rays kana mamwe marudzi e radiation kuuraya cancer maseru kana kuachengeta iwo kuti asakure. Kune mhando mbiri dze radiation radiation:

• External radiation therapy inoshandisa muchina uri kunze kwemuviri kutumira radiation kune kenza.

• Yemukati radiation kurapwa kunoshandisa radioactive chinhu chakavharirwa mune tsono, mhodzi, waya, kana makateti anoiswa akananga mukati kana padyo nekenza.

Maitiro ekurapwa nemwaranzi anoenderana nerudzi uye nhanho yekenza iri kurapwa. Kunze uye kwemukati kurapwa kwemwaranzi kunoshandiswa kurapa kenza yemendometri, uye inogona zvakare kushandiswa senge palliative kurapwa kubvisa zviratidzo uye nekuvandudza hupenyu hwehupenyu.

Chemotherapy

Chemotherapy mushonga wekenza unoshandisa mishonga kumisa kukura kwemasero ekenza, kungave nekuuraya maseru kana nekumisa maseru kubva pakupatsanuka. Kana chemotherapy ikatorwa nemuromo kana kujowa mutsinga kana mhasuru, mishonga inopinda muropa uye inogona kusvika masero emukenza mumuviri wese (systemic chemotherapy). Kana chemotherapy ikaiswa yakanangana necerebrospinal fluid, nhengo, kana dumbu remuviri senge dumbu, iwo madhiragi anonyanya kukanganisa cancer maseru munzvimbo idzodzo (remunharaunda chemotherapy).

Nzira iyo chemotherapy inopihwa inoenderana nerudzi uye nhanho yekenza iri kurapwa.

Hormone kurapa

Hormone kurapwa kurapa kenza inobvisa mahormone kana ichivhara maitiro avo uye inomisa maseru ekenza kubva mukukura. Mahormone zvinhu zvinogadzirwa nemaronda mumuviri uye zvinotenderera muropa. Mamwe mahormone anogona kukonzera mamwe cancer kuti ikure. Kana bvunzo dzichiratidza kuti maseru egomarara ane nzvimbo dzinogona kubatirira mahormone (receptors), zvinodhaka, kuvhiyiwa, kana kurapwa nemwaranzi kunoshandiswa kudzikisa kugadzirwa kwehormone kana kuvharidzira kushanda.

Targeted kurapwa

Targeted therapy mhando yekurapa inoshandisa zvinodhaka kana zvimwe zvinhu kuti zvione uye kurwisa chaiwo maseru ekenza pasina kukuvadza zvakajairika maseru. Monoclonal antibodies, mTOR inhibitors, uye chiratidzo transduction inhibitors ndiwo matatu marudzi eanotarisirwa kurapwa anoshandiswa kurapa endometrial cancer.

• Monoclonal antibody therapy ndeye kenza kurapa iyo inoshandisa antibodies inogadzirwa murabhoritari kubva kune imwechete mhando ye immune immune cell. Aya ma antibodies anokwanisa kuona zvinhu pane cancer cancer kana zvakajairika zvinhu zvinogona kubatsira gomarara maseru kukura. Masoja ekudzivirira chirwere anonamira pazvinhu uye anouraya maseru egomarara, anovharira kukura kwawo, kana kuachengeta kuti asapararire. Monoclonal antibodies inopihwa nekumisirwa. Inogona kushandiswa yoga kana kutakura zvinodhaka, chepfu, kana zvinhu zvine radioactive zvakanangana nemasero ekenza. Bevacizumab inoshandiswa kurapa nhanho yechitatu, nhanho IV, uye gomarara rinowanzoitika endometrial.

• mTOR inhibitors inovhara puroteni inonzi mTOR, iyo inobatsira kudzora kupatsanurwa kwemasero. mTOR inhibitors inogona kuchengetedza maseru ekenza kubva mukukura uye kudzivirira kukura kwemitsipa yeropa mitsva iyo mamota anoda kukura. Everolimus uye ridaforalimus anoshandiswa kurapa nhanho yechitatu, nhanho IV, uye gomarara rinowanzoitika endometrial.

• Signal transduction inhibitors inovhara masign anowedzerwa kubva kune imwe mamorekuru kuenda kune imwe mukati mechitokisi. Kuvhara zviratidzo izvi kunogona kuuraya maseru ekenza. Metformin iri kuongororwa kurapa nhanho yechitatu, nhanho IV, uye gomarara rinodzokororwa remendometri.

Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

Ruzivo nezve kiriniki miedzo inowanikwa kubva kuNCI webhusaiti.

Kurapa kwekenza yemendometriya kunogona kukonzera mhedzisiro.

Kuti uwane ruzivo nezve mhedzisiro inokonzerwa nekurapwa kwegomarara, ona yedu Side Mhedzisiro peji.

Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

Kune vamwe varwere, kutora chikamu mumuedzo wekiriniki inogona kunge iri sarudzo yekurapa yakanyanya kunaka. Kliniki miedzo chikamu chekenza tsvagiridzo. Zvemakiriniki miedzo inoitwa kuti uone kana marapirwo matsva egomarara akachengeteka uye achishanda kana zvirinani pane akajairwa kurapwa.

Mazhinji emazuva ano marapirwo akajairwa ekenza akavakirwa pamavambo emakiriniki ekuedzwa. Varwere vanotora chikamu mukuyedzwa kwekiriniki vanogona kuwana kurapwa kwakaringana kana kuve pakati pevekutanga kurapwa kutsva.

Varwere vanotora chikamu mumiedzo yekiriniki zvakare vanobatsira kugadzirisa marapirwo achaitwa kenza mune ramangwana. Kunyangwe kana miedzo yemakiriniki isinga tangire kumarapirwo matsva anoshanda, anowanzo pindura mibvunzo yakakosha uye anobatsira kufambisira mberi kutsvagurudza.

Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kenza kurapwa.

Mimwe miedzo yekiriniki inosanganisira chete varwere vasati vagamuchira kurapwa. Mimwe miedzo yekuedza kurapwa kwevarwere vane kenza haina kuve nani. Kune mamwezve emakiriniki miedzo inoedza nzira nyowani dzekumisa cancer kubva kudzokororazve (kudzoka) kana kudzikisira mhedzisiro yemakenza kurapwa.

Kuedzwa kwemakiriniki kuri kuitika munzvimbo zhinji dzenyika. Ruzivo nezve kiriniki miedzo inotsigirwa neNCI inogona kuwanikwa paNCI yekiriniki miedzo yekutsvaga peji rewebhu. Kliniki miedzo inotsigirwa nemamwe masangano inogona kuwanikwa pane yeClinicalTrials.gov webhusaiti.

Yekutevera-bvunzo inogona kudikanwa.

Mimwe miedzo yakaitwa kuongorora gomarara kana kutsvaga danho rekenza inogona kudzokororwa. Dzimwe bvunzo dzinodzokororwa kuitira kuti vaone kuti kurapa kuri kushanda sei. Sarudzo nezvekuti uenderere mberi, shandura, kana kumisa kurapwa kunogona kunge kuchibva pamhedzisiro yeiyi bvunzo.

Mimwe bvunzo ichaenderera ichiitwa nguva nenguva mushure mekunge kurapwa kwapera. Mhedzisiro yeiyi bvunzo inogona kuratidza kana mamiriro ako achinja kana kana gomarara radzoka (dzoka). Iyi bvunzo dzimwe nguva inonzi yekuteedzera-bvunzo kana kuongorora-kumusoro.

Kurapa Sarudzo nedanho

Muchikamu chino

• Chikamu I uye Chikamu II Endometrial Kenza

• Stage III, Chikamu IV, uye Yakajairika Endometrial Kenza

Kuti uwane ruzivo nezve marapirwo akanyorwa pazasi, ona iyo Chikamu Sarudzo Yekutarisa Chikamu.

Chikamu I uye Chikamu II Endometrial Kenza

Kenza-endometrial cancer (giredhi 1 kana giredhi 2)

Kurapa kwepasi-panjodzi nhanho ini endometrial kenza uye nhanho II endometrial kenza inogona kusanganisira zvinotevera:

• Kuvhiya (yakazara hysterectomy uye bilateral salpingo-oophorectomy). Lymph node mumapapiro uye mudumbu zvinogona zvakare kubviswa uye kutariswa pasi pe microscope kutarisa masero ekenza.

• Kuvhiya (yakazara hysterectomy uye bilateral salpingo-oophorectomy, iine kana isina kubviswa kwema lymph node mupfupa nemudumbu) inoteverwa neyemukati radiation kurapwa. Mune zvimwe zviitiko, kwokunze nemwaranzi kurapwa kune chiuno kunogona kushandiswa panzvimbo yemukati radiation kurapwa.

• Radiation kurapa chete kune varwere vasingakwanise kuvhiyiwa.

• Kuongororwa kwekiriniki kweiyo nyowani chemotherapy regimen.

Kana gomarara rapararira kumuromo wechibereko, hysterectomy yakakura ine nyika mbiri salpingo-oophorectomy inogona kuitwa.

Kenza ine njodzi yepamusoro-soro (giredhi 3)

Kurapa kwenzvimbo ine njodzi huru I kenza yemendometri uye nhanho II kenza yemendometri inogona kusanganisira zvinotevera:

• Kuvhiya (radical hysterectomy uye bilateral salpingo-oophorectomy). Lymph node mumapapiro uye mudumbu zvinogona zvakare kubviswa uye kutariswa pasi pe microscope kutarisa masero ekenza.

• Kuvhiya (radical hysterectomy uye bilateral salpingo-oophorectomy) inoteverwa nekemotherapy uye dzimwe nguva radiation radiation.

• Kuongororwa kwekiriniki kweiyo nyowani chemotherapy regimen.

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Stage III, Chikamu IV, uye Yakajairika Endometrial Kenza

Kurapa kwekenza III endometrial cancer, cancer IV endometrial kenza, uye inowanzoitika endometrial kenza inogona kusanganisira zvinotevera:

• Kuvhiya (radical hysterectomy uye kubviswa kwema lymph node mumapapiro kuitira kuti vagone kutariswa pasi pe microscope kutarisa maseru ekenza) ichiteverwa neadjuvant chemotherapy uye / kana radiation radiation.

• Chemotherapy uye yemukati neyekunze radiation kurapwa kwevarwere vasingakwanise kuvhiyiwa.

• Hormone kurapwa kwevarwere vasingakwanise kuvhiyiwa kana radiation radiation.

• Targeted therapy ne mTOR inhibitors (everolimus kana ridaforolimus) kana monoclonal antibody (bevacizumab).

• Kuongororwa kwekiriniki kweiyo nyowani yekurapa regimen iyo inogona kusanganisira kusanganisa chemotherapy, yakanangwa kurapwa, senge mTOR inhibitor (everolimus) kana chiratidzo transduction inhibitor (metformin) uye

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Kuti Udzidze Zvakawanda Nezve Endometrial Kenza

Kuti uwane rumwe ruzivo kubva kuNational Cancer Institute nezve cancer endometrial, ona zvinotevera:

• Uterine Kenza Kumba Peji

• Kudzivirira Kenza yeKendometri

• Endometrial Cancer Kuongorora

• Hormone Therapy yeCancer yeCancer

Kuti uwane ruzivo rwekenza uye zvimwe zviwanikwa kubva kuNational Cancer Institute, ona zvinotevera:

• Nezve Kenza

• Stage

• Chemotherapy uye Iwe: Tsigiro Yevanhu Vane Kenza

• Radiation Therapy uye Iwe: Rutsigiro rweVanhu Vane Kenza

• Kurarama neCancer

• Mibvunzo Yekubvunza Wako Chiremba nezveCancer

• Kune Vakapona uye Vanotarisira