Mhando / nyoro-tishu-sarcoma / murwere / rhabdomyosarcoma-kurapwa-pdq

Yevacheche Rhabdomyosarcoma Kurapa (®) -Patient Shanduro

Ruzivo Ruzhinji Nezvehucheche Rhabdomyosarcoma

Yehudiki rhabdomyosarcoma chirwere umo mune yakaipa (kenza) maseru anoumba mune mhasuru nyama.

Rhabdomyosarcoma rudzi rwe sarcoma. Sarcoma kenza yezvinyoro nyoro (senge mhasuru), inosanganisa matishu (senge tendon kana shwashwa), kana pfupa. Rhabdomyosarcoma inowanzotanga mumhasuru dzakabatanidzwa nemapfupa uye dzinobatsira muviri kufamba. Rhabdomyosarcoma ndiyo yakajairika mhando sosi yenyoro sarcoma muvana. Inogona kutanga munzvimbo zhinji mumuviri.

Kune matatu makuru marudzi e rhabdomyosarcoma:

• Embryonal: Rudzi urwu runowanzoitika kazhinji mumusoro nemutsipa nzvimbo kana munhengo yekubereka kana yeweti, asi inogona kuitika chero mumuviri. Iyo ndiyo yakajairika mhando yerhabdomyosarcoma.

• Alveolar: Rudzi urwu runowanzoitika mumawoko kana makumbo, chifuva, dumbu, nhengo dzesikarudzi, kana nzvimbo yekumashure.

• Anaplastic: Urwu ndirwo rudzi rusinganyanyozivikanwa rwe rhabdomyosarcoma muvana.

Ona inotevera pfupiso yekurapa ye yeruzivo nezve mamwe marudzi easoftoma sarcoma:

• Yehucheche Nyoro Tissue Sarcoma

• Nyama Yakakura Nyoro Sarcoma

Zvimwe zvemagene mamiriro zvinowedzera njodzi yehudiki rhabdomyosarcoma.

Chero chipi zvacho chinowedzera njodzi yekuwana chirwere chinonzi njodzi chinhu. Kuva nenjodzi hazvireve kuti uchawana gomarara; kusava nenjodzi hazvireve kuti hauzobatwe negomarara. Taura nachiremba wemwana wako kana iwe uchifunga kuti mwana wako angave ari panjodzi.

Njodzi zvinhu zve rhabdomyosarcoma zvinosanganisira kuve nezvirwere zvinotevera zvakagara nhaka:

• Li-Fraumeni chirwere.

• Pleuropulmonary blastoma.

• Neurofibromatosis mhando 1 (NF1).

• Costello chirwere.

• Beckwith-Wiedemann chirwere.

• Noonan chirwere.

Vana vaive nehuremu hwekuzvarwa zvakanyanya kana vaive vakuru pane vaitarisirwa pakuzvarwa vanogona kuve nenjodzi yekuwedzera yeembryonal rhabdomyosarcoma.

Muzviitiko zvakawanda, chikonzero che rhabdomyosarcoma hachizivikanwe.

Chiratidzo chehudiki rhabdomyosarcoma bundu kana kuzvimba kunoramba kuchikura.

Zviratidzo nezviratidzo zvinogona kukonzerwa nehucheche rhabdomyosarcoma kana nemamwe mamiriro. Zviratidzo nezviratidzo zvinoitika zvinoenderana nekenza kenza. Tarisa nechiremba wemwana wako kana mwana wako ane chero chinotevera:

• Bundu kana kuzvimba kunoramba kuchikura kana kusingaendi. Zvinogona kurwadza.

• Kuputika kweziso.

• Kutemwa nemusoro.

• Kunetseka kuita weti kana kuita ura.

• Ropa mune weti.

• Kubuda ropa mumhino, pahuro, mukadzi, kana rectum.

Kuongorora kuongororwa uye bhiopsy inoshandiswa kuona (tsvaga) uye kuongorora hudiki rhabdomyosarcoma.

Iko kuongororwa kwekuyedza kunoitwa kunoenderana nechikamu panogadzirwa gomarara. Iyi inotevera bvunzo uye maitiro anogona kushandiswa:

• Kuongorora kwepanyama uye nhoroondo: Kuongororwa kwemuviri kutarisa zviratidzo zvehutano, kusanganisira kuongorora zviratidzo zvehosha, zvakadai semapundu kana chero chinhu chinoratidzika sechisina kujairika. Nhoroondo yemaitiro ehutano hwemurwere uye kurwara kwakapfuura uye kurapwa kuchatorwawo.

• X-ray: X-ray yenhengo nemapfupa mukati memuviri, senge chipfuva. X-ray imhando yesimba remagetsi rinogona kupfuura nemuviri uye kupinda mufirimu, richiita mufananidzo wenzvimbo dziri mukati memuviri.

• CT scan (CAT scan): Maitiro anoita akateedzana emifananidzo yakajeka yenzvimbo dziri mukati memuviri, senge chipfuva, dumbu, pelvis, kana lymph node, inotorwa kubva kumakona akasiyana. Mifananidzo yacho inogadzirwa nekombuta yakabatana neiyo x-ray muchina. Dhayi inogona kuiswa jekiseni kana kumedzwa kubatsira nhengo kana zvinyama kuratidza zvakajeka. Iyi nzira inonziwo computed tomography, computerized tomography, kana komputa axial tomography.

Computed tomography (CT) scan yemudumbu. Mwana akarara patafura inotsvedza kuburikidza neCT scanner, iyo inotora mifananidzo ye x-ray yemukati medumbu.

• MRI (magnetic resonance imaging): Maitiro anoshandisa magineti, masaisai eredhiyo, uye komputa kugadzira yakateedzana mifananidzo yakajeka yenzvimbo dzemuviri, senge dehenya, huropi, uye node node. Iyi nzira inonziwo nyukireya magnetic resonance imaging (NMRI).

Magnetic resonance imaging (MRI) yedumbu. Mwana akarara patafura inotsvedza ichipinda muMRI scanner, inotora mifananidzo yemukati memuviri. Iyo padhi padumbu remwana inobatsira kujekesa mifananidzo.

• PET scan (positron emission tomography scan): Iyo nzira yekuwana yakaipa malonda maseru mumuviri. Chishoma che radioactive glucose (shuga) inoiswa mutsinga. Iyo PET scanner inotenderera yakatenderedza muviri uye inogadzira mufananidzo wepo glucose iri kushandiswa mumuviri. Malignant tumarara maseru anoratidza kupenya mumufananidzo nekuti anoshanda uye anotora glucose yakawanda kupfuura zvinoita maseru akajairwa.

Positron emission tomography (PET) scan. Mwana akarara patafura inotsvedza nepena scanner yePET. Musoro zororo uye tambo chena zvinobatsira mwana kunyepa zvakanyarara. Chishoma che radioactive glucose (shuga) inoiswa mutsinga yemwana, uye scanner inogadzira mufananidzo wekuti glucose irikushandiswa sei mumuviri. Cancer maseru anoratidza kupenya mumufananidzo nekuti anotora yakawanda glucose kupfuura zvakajairwa maseru.

• Bone scan: Maitiro ekutarisa kana paine nekukurumidza kupatsanura masero, senge kenza maseru, mupfupa. Chinhu chidiki kwazvo che radioactive chakabayiwa mutsinga uye chinofamba neropa. Iyo radioactive zvinhu inounganidza mumapfupa nekenza uye inoonekwa ne scanner.

Bone scan. Chinhu chidiki che radioactive chakabayiwa mutsinga yemwana uye chinofamba kuburikidza neropa. Iyo radioactive zvinhu inounganidza mumapfupa. Sezvo mwana akarara patafura inotsvedza pasi pe scanner, izvo zvine radioactive zvinoonekwa uye mifananidzo inogadzirwa pakombuta.

• Bone marrow aspiration uye biopsy: Kubviswa kwemongo wemapfupa, ropa, uye chidimbu chefupa nekuisa tsono isina mhango muhudyu. Samples inobviswa kubva muchiuno chiuno. Nyanzvi yezvirwere anoona pfupa, ropa, uye pfupa pasi pe microscope kutsvaga zviratidzo zvegomarara.

Bone marora chishuwo uye biopsy. Mushure mekunge nzvimbo diki yeganda yave nechiveve, tsono yemongo wemapfupa inoiswa mupfupa rehudyu remwana. Samples reropa, bhonzo, uye mwongo wemapfupa zvinobviswa kuti zviongororwe pasi pe microscope.

• Lumbar puncture: Maitiro anoshandiswa kutora cerebrospinal fluid (CSF) kubva pamutsipa wepelinha. Izvi zvinoitwa nekuisa tsono pakati pemabhonzo maviri mumuzongoza nekupinda muCSF yakakomberedza musana uye kubvisa sampu yemvura. Muenzaniso we CSF unotariswa pasi pe microscope yezviratidzo zvecancer maseru. Maitiro aya anonzi zvakare LP kana musana tap.

Kana bvunzo idzi dzichiratidza panogona kunge paine rhabdomyosarcoma, biopsy inoitwa. Bhiopsy ndiko kubviswa kwemasero kana zvinyama kuitira kuti zvionekwe pasi pe microscope nachiremba wekutarisa zviratidzo zvecancer Nekuti kurapwa kunoenderana nerudzi rwe rhabdomyosarcoma, biopsy sampuli inofanira kuongororwa nachiremba ane ruzivo rwekuongorora rhabdomyosarcoma.

Imwe yedzinotevera mhando dze biopsies dzinogona kushandiswa:

• Fine-sindano aspiration (FNA) biopsy: Kubviswa kwetissue kana fluid kushandisa tsono yakatetepa.

• Core tsono biopsy: Kubviswa kwetishu uchishandisa yakakura tsono. Maitiro aya anogona kutungamirwa uchishandisa ultrasound, CT scan, kana MRI.

• Vhura biopsy: Kubviswa kwetishu kuburikidza necision (kucheka) kunoitwa paganda.

• Sentinel lymph node biopsy: Kubviswa kweiyo sentinel lymph node panguva yekuvhiyiwa. Iyo sentinel lymph node ndiyo yekutanga lymph node muboka rema lymph node ekugamuchira lymphatic drainage kubva kune yekutanga bundu. Iyo yekutanga lymph node kenza ingangopararira ichienda kubva kune yekutanga bundu. Chinhu chine radioactive uye / kana dhayi yebhuruu inorohwa padyo nebundu. Icho chinhu kana dhayi inoyerera kuburikidza nemakiromita ducts kuenda kune ma lymph node. Iyo yekutanga lymph node yekugamuchira chinhu kana dhayi inobviswa. Nyanzvi yezvirwere anoona tishu pasi pe microscope kutsvaga maseru ekenza. Kana masero emukenza asingawanikwe, zvinogona kunge zvisiri kudikanwa kubvisa mamwe ma "lymph node". Dzimwe nguva, sentinel lymph node inowanikwa mune anopfuura rimwe boka renzvimbo.

Iyi bvunzo inotevera inogona kuitwa pane sampuro yetishu inobviswa.

• Chiedza microscopy: Kuongororwa kwerabhoritari umo masero ari mune imwe sampuro yetishu anoonekwa pasi pemaitiro akajairika uye akakwirira-ane simba-simba kuona dzimwe shanduko mumasero.

• Immunohistochemistry: Chiyero chinoshandisa antibodies kutarisa mamwe maantigen mune sampuli yetishu. Masoja ekudzivirira chirwere anowanzo sunganidzwa nechinhu chine radioactive kana dhayi inokonzeresa kuti munyama uvheneke pasi pe microscope. Rudzi urwu rweyedzo runogona kushandiswa kutaurira mutsauko pakati pemhando dzakasiyana dzekenza.

• FISH (fluorescence in situ hybridization): Kuedzwa kwerabhoritari kunoshandiswa kutarisa majeni kana ma chromosomes mumasero nematukisi. Zvidimbu zveDNA zvine dhayi yemagetsi zvinogadzirwa murabhoritari uye zvinowedzerwa kumasero kana zvinyama pane girazi rinotsvedza. Kana zvidimbu izvi zveDNA zvakanamatira kune mamwe majeni kana nzvimbo dzema chromosomes pane iwo mutserendende, zvinovheneka kana zvichitariswa pasi pe microscope ine mwenje wakakosha. Rudzi urwu rweyedzo runoshandiswa kutsvaga mamwe majini shanduko.

• Reverse transcript- polymerase chain reaction (RT – PCR) bvunzo: Kuongororwa kwerabhoritari umo masero ari mune imwe sampu yetishu anodzidza achishandisa makemikari kutsvaga shanduko mune chimiro kana mashandiro emajini.

• Kuongorora kweCytogenetic: Kuedzwa kwerabhoritari umo masero ari mune imwe sampu yetinyama anoonekwa pasi pe microscope kutsvaga dzimwe shanduko muma chromosomes.

Zvimwe zvinhu zvinokanganisa kufungidzira (mukana wekupora) uye sarudzo dzekurapa.

Kufungidzira (mukana wekupora) uye sarudzo dzekurapa dzinoenderana nezvinotevera:

• Zera remurwere.

• Iko mumuviri bundu rakatanga.

• Kukura kwebundu panguva yekuongororwa.

• Kunyangwe bundu racho rakabviswa zvachose nekuvhiyiwa.

• Rudzi rwe rhabdomyosarcoma (embryonal, alveolar, kana anaplastic).

• Kunyangwe paine zvimwe zvinoshanduka mumajini.

• Kunyangwe bundu racho rakanga rapararira kune dzimwe nhengo dzomuviri panguva yekuongororwa.

• Kunyangwe iro bundu raive mune ma lymph node panguva yekuongororwa.

• Kunyangwe bundu racho rinopindura chemotherapy uye / kana radiation radiation.

Kune varwere vane kenza inowanzoitika, kufungidzira uye kurapwa kunoenderana nezvinotevera:

• Iko mumuviri bundu rakadzokazve (rakadzoka).

• Inguva yakadii yakapfuura pakati pekupera kwekurapwa kwegomarara uye kenza payakadzokazve.

• Kunyangwe iro bundu rakarapwa ne radiation radiation.

Matanho ehucheche Rhabdomyosarcoma

PFUNGWA DZINOKOSHA

• Mushure mehudiki rhabdomyosarcoma yaonekwa, kurapwa kunoenderana muchikamu padanho rekenza uye dzimwe nguva kunoenderana nekuti kenza yese yakabviswa nekuvhiyiwa.

• Pane nzira nhatu dzinopararira negomarara mumuviri.

• Gomarara rinogona kutapukira kubva kwarakatanga kuenda kune dzimwe nhengo dzemuviri.

• Kutara kwehudiki rhabdomyosarcoma kunoitwa muzvikamu zvitatu.

• Iyo yekugadzika sisitimu inoenderana nesaizi yebundu, iri mumuviri, uye kana yapararira kune dzimwe nhengo dzomuviri:

• Chikamu 1

• Chikamu 2

• Chikamu 3

• Chikamu 4

• Iyo yekugadzika system inoenderana nekuti kenza yapararira uye kana iyo kenza yese yakabviswa nekuvhiyiwa:

• Boka I

• Boka II

• Boka III

• Boka IV

• Iri boka renjodzi rakavakirwa pane iyo sisitimu sisitimu uye iyo yekumisikidza system.

• Yakadzika-panjodzi yehudiki rhabdomyosarcoma

• Pakati-panjodzi panjodzi rhabdomyosarcoma

• Yakakwira-njodzi panjodzi rhabdomyosarcoma

Mushure mehudiki rhabdomyosarcoma yaonekwa, kurapwa kunoenderana muchikamu padanho rekenza uye dzimwe nguva kunoenderana nekuti kenza yese yakabviswa nekuvhiyiwa.

Maitiro anoshandiswa kutsvaga kana gomarara rapararira mukati memitezo kana kune dzimwe nhengo dzemuviri inonzi staging. Izvo zvakakosha kuti uzive nhanho kuitira kuronga kurapwa. Chiremba anoshandisa mhedzisiro yekuongororwa bvunzo kuti abatsire kuziva danho rechirwere.

Kurapa kwehudiki rhabdomyosarcoma kunoenderana muchikamu padariro uye dzimwe nguva pahuwandu hwekenza inosara mushure mekuvhiyiwa kubvisa bundu. Iyo pathologist inoshandisa microscope kutarisa matishu abviswa panguva yekuvhiyiwa, kusanganisira masuru sampuli kubva kumucheto kwenzvimbo dzakatobviswa cancer. Izvi zvinoitirwa kuti uone kana ese maseru ekenza akatorwa kunze kwekuvhiyiwa.

Pane nzira nhatu dzinopararira negomarara mumuviri.

Kenza inogona kupararira kuburikidza nematinji, iyo lymph system, uye neropa:

• Tishu. Kenza inopararira kubva kwayakatanga nekukura ichipinda munzvimbo dziri pedyo.

• Lymph maitiro. Kenza inopararira kubva kwayakatanga nekupinda muiyo lymph system. Kenza inofamba nemumidziyo yema lymph ichienda kune dzimwe nhengo dzemuviri.

• Ropa. Kenza inopararira kubva payakatanga nekupinda muropa. Kenza inofamba nemidzi yeropa ichienda kune dzimwe nhengo dzemuviri.

Gomarara rinogona kutapukira kubva kwarakatanga kuenda kune dzimwe nhengo dzemuviri.

Kana kenza ikapararira kune chimwe chikamu chemuviri, inonzi metastasis. Cancer maseru anotsemuka kubva kwaakatanga (iro bundu rekutanga) uye achifamba kuburikidza neye lymph system kana ropa.

Lymph maitiro. Gomarara rinopinda mu "lymph system", rinofamba nemumidziyo ye "lymph", uye rinogadzira bundu (metastatic tumor) mune chimwe chikamu chemuviri. Ropa. Kenza inopinda muropa, inofamba nemutsinga dzeropa, yoita bundu (metastatic tumor) mune chimwe chikamu chemuviri. Iyo metastatic bundu irwo rudzi rwecancer seyakanyanya bundu. Semuenzaniso, kana rhabdomyosarcoma ikapararira kuenda kumapapu, masero ekenza mumapapu ndiwo maseru e rhabdomyosarcoma. Hosha iyi metastatic rhabdomyosarcoma, kwete kenza yemapapu.

Kutara kwehudiki rhabdomyosarcoma kunoitwa muzvikamu zvitatu.

Udiki rhabdomyosarcoma yakarongedzwa nekushandisa nzira nhatu dzakasiyana dzekutsanangudza gomarara:

• Sisitimu yekuratidzira.
• Kurongeka kwemaitiro.
• Boka rine njodzi.

Iyo yekugadzika sisitimu inoenderana nesaizi yebundu, iri mumuviri, uye kana yapararira kune dzimwe nhengo dzomuviri:

Chikamu 1

Muchikamu chekutanga, bundu iri chero saizi, inogona kunge yakapararira kune lymph node, uye inowanikwa mune imwe chete yeanotevera masosi "akanaka":

• Ziso kana nzvimbo yakatenderedza ziso.

• Musoro uye mutsipa (asi kwete munyama iri padhuze nehuropi uye musana).

• Gallbladder uye bile ducts.

• Ureters kana urethra.

• Miedzo, ovary, nyini, kana chibereko.

Rhabdomyosarcoma iyo inoumba mune "inofadza" saiti ine fungidziro iri nani. Kana saiti panowanikwa gomarara haisi imwe yenzvimbo dzinodiwa dzakanyorwa pamusoro, inonzi inzvimbo "isingafadzi".

Saizi yemamota inowanzo kuyerwa mukati masendimita (cm) kana inches. Zvekudya zvakajairika zvinogona kushandiswa kuratidza kukura kwemarara mumasendimita zvinosanganisira: pizi (1 cm), nzungu (2 cm), mazambiringa (3 cm), walnuts (4 cm), lime (5 cm kana 2 masendimita), zai (6 cm), peach (7 cm), uye grapefruit (10 cm kana 4 inches).

Chikamu 2

Muchikamu chechipiri, gomarara rinowanikwa mune "isina kunaka" saiti (chero nzvimbo imwe isina kutsanangurwa se "inofadza" muchikamu chekutanga). Bundu harina kukura kupfuura masendimita mashanu uye harina kupararira kune lymph node.

Chikamu 3

Muchikamu chechitatu, gomarara rinowanikwa mune "isina kunaka" saiti (chero imwe nzvimbo isina kutsanangurwa se "inofadza" muchikamu chekutanga) uye chimwe cheanotevera ichokwadi:

• Bundu harina kukura kupfuura masendimita mashanu uye gomarara rapararira kune ma lymph node ari padyo.

• Bundu rakakura kupfuura masendimita mashanu uye gomarara rinogona kunge rakapararira kune ma lymph node ari padyo.

Chikamu 4

Muchikamu chechina, bundu rinogona kunge riri chero saizi uye kenza inogona kunge yakapararira kune ma lymph node ari padyo. Kenza yakapararira kumativi ari kure emuviri, senge mapapu, mwongo wemabhonzo, kana pfupa.

Iyo yekugadzika system inoenderana nekuti kenza yapararira uye kana iyo kenza yese yakabviswa nekuvhiyiwa:

Boka I

Gomarara rakawanikwa panzvimbo payakatangira uye rakabviswa chose nekuvhiyiwa. Tissue yakatorwa kubva kumicheto kwekubviswa bundu. Iyo turu yakatariswa pasi pe microscope nachiremba uye hapana maseru ekenza akawanikwa.

Boka II

Boka II rakakamurwa kuita mapoka IIA, IIB, uye IIC.

• IIA: Gomarara rakabviswa nekuvhiyiwa asi maseru emukenza akaonekwa apo nyama, yakatorwa kubva kumucheto kwenzvimbo yakabviswa bundu, yaionekwa pasi pe microscope nachiremba.

• IIB: Cancer yakanga yapararira kune ma lymph node ari padyo uye cancer uye lymph node dzakabviswa nekuvhiya.

• IIC: Cancer yakanga yapararira kune ma lymph node ari padyo, gomarara uye lymph node zvakabviswa nekuvhiya, uye chimwe chete cheanotevera ichokwadi:

• Tissue inotorwa kubva kumucheto kwekubviswa bundu iri yakaongororwa pasi pe microscope nachiremba uye maseru ekenza akaonekwa.

• Iyo yakanyanyisa kureba node kubva pabundu rakabviswa yakaongororwa pasi pe microscope nachiremba uye maseru ekenza akaonekwa.

Boka III

Gomarara rakabviswa pamwe nebiopsy kana kuvhiyiwa asi pane bundu rasara iro rinoonekwa neziso.

Boka IV

• Kenza yakanga yapararira kumativi ari kure emuviri pakaonekwa chirwere checancer.

• Cancer maseru anowanikwa nemuyedzo wekufungidzira; kana

Kune masero egomarara mukati memvura inenge yakatenderedza huropi, musana, kana mapapu, kana mune mvura iri mudumbu; kana mapundu anowanikwa munzvimbo idzodzo.

Iri boka renjodzi rakavakirwa pane iyo sisitimu sisitimu uye iyo yekumisikidza system.

Boka renjodzi rinotsanangura mukana wekuti rhabdomyosarcoma ichadzoka (kudzoka). Mwana wese anorapwa rhabdomyosarcoma anofanirwa kuwana chemotherapy kudzikisa mukana wekenza unodzokazve. Rudzi rweanticancer mushonga, dhizaini, uye huwandu hwekurapa wakapihwa zvinoenderana nekuti mwana ane njodzi yakadzika, yepakati-njodzi, kana yakanyanya njodzi rhabdomyosarcoma.

Aya anotevera mapoka enjodzi anoshandiswa:

Yakadzika-panjodzi yehudiki rhabdomyosarcoma

• Yakaderera-njodzi yehudiki rhabdomyosarcoma ndeimwe yeanotevera:

Bundu remumbroni rehukuru hwese hunowanikwa mune "yakanaka" saiti. Panogona kunge paine bundu rinosara mushure mekuvhiyiwa iro rinoonekwa kana risina microscope. Kenza inogona kunge yakapararira kune ma lymph node ari padyo. Idzi dzinotevera nzvimbo "dzakanaka" saiti:

• Ziso kana nzvimbo yakatenderedza ziso.

• Musoro kana mutsipa (asi kwete munyama padyo nenzeve, mhino, zvitadzo, kana chigadziko chedehenya).

• Gallbladder uye bile ducts.

• Ureter kana urethra.

• Miedzo, ovary, nyini, kana chibereko.

Bundu rembryonal rehukuru hwese husingawanikwe mu "yakanaka" saiti. Panogona kunge paine bundu rakasara mushure mekuvhiyiwa iro rinogona kungoonekwa chete nemaikorosikopu. Kenza inogona kunge yakapararira kune ma lymph node ari padyo.

Pakati-panjodzi panjodzi rhabdomyosarcoma

Pakati-panjodzi panjodzi rhabdomyosarcoma ndeimwe yeanotevera:

• Bundu remumimba rehukuru hwese husingawanikwe mune imwe ye "yakanaka" masosi akanyorwa pamusoro. Pane bundu rasara mushure mekuvhiyiwa, iro rinogona kuoneka kana kana pasina maikorosikopu. Kenza inogona kunge yakapararira kune ma lymph node ari padyo.

• Bundu reropa rehukuru hwese mune saiti "inofadza" kana "isina kunaka". Panogona kunge paine bundu rinosara mushure mekuvhiyiwa iro rinoonekwa kana risina microscope. Kenza inogona kunge yakapararira kune ma lymph node ari padyo.

Yakakwira-njodzi panjodzi rhabdomyosarcoma

Yakanyanya-njodzi pwere rhabdomyosarcoma inogona kunge iri embryonal mhando kana alveolar mhando. Inogona kunge yakapararira kune lymph node iri padyo uye yakapararira kune imwe kana kupfuura anotevera:

• Dzimwe nhengo dzemuviri dzisiri pedyo nekwakatanga kuumbwa bundu.

• Fluid yakatenderedza uropi kana musana.

• Fluid mumapapu kana mudumbu.

Dzokororo Yehucheche Rhabdomyosarcoma

Kudzokorora kwehudiki rhabdomyosarcoma kenza yakadzokazve (kudzoka) mushure mekurapwa. Gomarara rinogona kudzoka panzvimbo imwechete kana mune zvimwe zvikamu zvemuviri, zvakaita semapapu, pfupa, kana mwongo wemabhonzo. Zvishoma kazhinji, rhabdomyosarcoma inogona kudzoka muzamu mune vechidiki vakadzi kana muchiropa.

Kurapa Sarudzo Kuongorora

PFUNGWA DZINOKOSHA

• Kune akasiyana marudzi ekurapa kwevarwere vanehudiki rhabdomyosarcoma.

• Vana vane rhabdomyosarcoma vanofanirwa kurapwa kwavo kuchirongwa nechikwata chevanoona nezvehutano vari nyanzvi pakurapa kenza muvana.

• Kurapa kwehudiki rhabdomyosarcoma kunogona kukonzera mhedzisiro.

• Mhando mitatu yekurapa kwakajairika inoshandiswa:

• Kuvhiya

• Radiation kurapa

• Chemotherapy

• Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

• Immunotherapy

• Targeted kurapwa

• Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

• Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kenza kurapwa.

• Yekutevera-bvunzo inogona kudikanwa.

Kune akasiyana marudzi ekurapa kwevarwere vanehudiki rhabdomyosarcoma.

Mamwe marapirwo akajairwa (iko kurapwa kwazvino kwashandiswa), uye kumwe kuedzwa mumakiriniki ekuedzwa A kurapwa kiriniki kuyedzwa chidzidzo chekutsvaga chakaitirwa kubatsira kuvandudza marapirwo azvino kana kuwana ruzivo marapirwo matsva evarwere vane gomarara. Kana kiriniki miedzo ikaratidza kuti kurapwa kutsva kuri nani pane kwese kurapwa, kurapwa kutsva kunogona kuve kwakajairwa kurapwa.

Nekuti kenza muvana isingawanzo, kutora chikamu mukutongwa kwekiriniki kunofanirwa kutariswa. Mimwe miedzo yekiriniki yakavhurwa chete kune varwere vasina kutanga kurapwa.

Vana vane rhabdomyosarcoma vanofanirwa kurapwa kwavo kuchirongwa nechikwata chevanoona nezvehutano vari nyanzvi pakurapa kenza muvana.

Nekuti rhabdomyosarcoma inogona kuumba munzvimbo dzakasiyana dzemuviri, akawanda marudzi akasiyana ekurapa anoshandiswa. Kurapa kunozoonekwa nachiremba wevana oncologist, chiremba ane hunyanzvi hwekurapa vana vane gomarara. Vanachiremba oncologist vanoshanda nevamwe vatapi vezvehutano vari nyanzvi pakurapa vana vane rhabdomyosarcoma uye vanoziva mune dzimwe nzvimbo dzemishonga. Izvi zvinogona kusanganisira vanachiremba vanotevera:

• Chiremba wevana.

• Chiremba wechiremba wechiremba.

• Radiation oncologist.

• Chiremba wehematologist.

• Chiremba radiologist.

• Mukoti wechiremba nyanzvi.

• Geneticist kana gomarara genetics njodzi mupi wezano.

• Wezvemagariro.

• Rehabilitation nyanzvi.

Kurapa kwehudiki rhabdomyosarcoma kunogona kukonzera mhedzisiro.

Kuti uwane ruzivo nezve mhedzisiro inotanga panguva yekurapa kenza, ona yedu Side Mhedzisiro peji.

Zvimwe zvinokonzeresa kubva pakurapwa nekenza zvinotanga mushure mekurapwa uye kuenderera kwemwedzi kana makore zvinonzi kunonoka kuitika Kwapera nguva mhedzisiro yekenza kurapwa kweRhabdomyosarcoma inogona kusanganisira:

• Zvinetso zvepanyama.

• Shanduko mumanzwiro, manzwiro, kufunga, kudzidza, kana ndangariro.

• Gomarara repiri (mhando nyowani dzekenza).

Mimwe mhedzisiro mhedzisiro inogona kurapwa kana kudzorwa. Izvo zvakakosha kuti utaure navanachiremba vemwana wako nezve mhedzisiro yekurapwa nekenza kunogona kuve pamwana wako. (Ona pfupiso ye paMagumo Ekurapa kweKenza Yevacheche kuti uwane rumwe ruzivo.)

Mhando mitatu yekurapa kwakajairika inoshandiswa:

Kuvhiya

Kuvhiya (kubvisa kenza mukuvhiya) kunoshandiswa kurapa hudiki rhabdomyosarcoma. Rudzi rwekuvhiya runodaidzwa kuti rwakawanda rwekunze kunowanzoitwa. Kubviswa kwakawanda kwenzvimbo ndiko kubviswa kwetsinga uye zvimwe zvezvinyama zvakakomberedza, kusanganisira ma "lymph node". Kuvhiya kwechipiri kunogona kudikanwa kubvisa kenza yese. Kunyangwe kuvhiya kwaitwa uye mhando yekuvhiya yaitwa zvinoenderana nezvinotevera:

• Iko mumuviri bundu rakatanga.

• Mhedzisiro iyo kuvhiyiwa ichave nayo munzira iyo mwana achazotaridzika.

• Maitiro ekuvhiyiwa achave nawo pane akakosha mashandiro emuviri emwana.

• Kuti bundu rakapindura sei chemotherapy kana radiation radiation iyo inogona kunge yakapihwa kutanga.

Muvana vazhinji vane rhabdomyosarcoma, hazviite kuti vabvise bundu rese nekuvhiya.

Rhabdomyosarcoma inogona kuumba munzvimbo dzakasiyana mumuviri uye kuvhiya kunenge kwakasiyana pane yega yega saiti. Kuvhiya kwekurapa rhabdomyosarcoma yeziso kana nzvimbo dzepabonde kazhinji biopsy. Chemotherapy, uye dzimwe nguva kurapwa nemwaranzi, kunogona kupihwa usati wavhiyiwa kudzora mamota makuru.

Mushure mekunge chiremba abvisa kenza yese inoonekwa panguva yekuvhiyiwa, varwere vachazopihwa chemotherapy mushure mekuvhiyiwa kuuraya chero gomarara maseru akasara. Radiation therapy inogona zvakare kupihwa. Mushonga wakapihwa mushure mekuvhiyiwa, kudzikisa njodzi yekuti gomarara richadzoka, inonzi adjuvant therapy.

Radiation kurapa

Radiation kurapa kurapwa kenza iyo inoshandisa yakakwira-simba x-ray kana mamwe marudzi emwaranzi kuuraya cancer maseru kana kuamisa iwo kubva mukukura. Kune mhando mbiri dze radiation radiation:

• External radiation therapy inoshandisa muchina uri kunze kwemuviri kutumira radiation kune kenza. Dzimwe nzira dzekupa mishonga ye radiation dzinogona kubatsira kuchengetedza mwaranzi kubva mukukuvadza nyama iri pedyo ine hutano. Aya marudzi erapi radiation ekunze anosanganisira anotevera:

• Conformal radiation therapy: Conformal radiation kurapwa rudzi rwekunze radiation radiation iyo inoshandisa komputa kugadzira 3-dimensional (3-D) pikicha yebundu uye inoumba iwo mamirioni matanda kuti akwane bundu. Izvi zvinobvumidza mwero wepamusoro wemwaranzi kuti usvike pachironda uye unokonzeresa kukuvara kudiki kune hutano hwakanaka.

• Intensity-modulated radiation therapy (IMRT): IMRT rudzi rwe 3-dimensional (3-D) radiation radiation inoshandisa komputa kugadzira mifananidzo yehukuru uye chimiro chebundu. Matanda matete emwaranzi yemasimba akasiyana (simba) anovavarira bundu kubva pamakona mazhinji.

• Volumetrical modulated arc therapy (VMAT): VMAT rudzi rwe3-D radiation radiation inoshandisa komputa kugadzira mifananidzo yehukuru uye chimiro chebundu. Muchina we radiation unofamba mudenderedzwa uchitenderedza murwere kamwe panguva yekurapwa uye unotumira matanda matete emwaranzi yemasimba akasiyana (simba) pabundu. Kurapa neVMAT kunoendeswa nekukurumidza kupfuura kurapwa neIMRT.

• Stereotactic muviri radiation radiation: Stereotactic muviri radiation radiation rudzi rwekunze radiation radiation. Zvishandiso zvakakosha zvinoshandiswa kuisa murwere munzvimbo imwechete kune imwe neimwe radiation kurapwa. Kamwe pazuva kwemazuva akati wandei, muchina we radiation unovavarira mwero wakakura kupfuura wenguva dzose wemwaranzi yakananga pabundu. Nekuva nemurwere munzvimbo imwechete yekurapwa kwega kwega, pane kukuvara kudiki kune zvinyama zviri pedyo zvine hutano. Maitiro aya anonziwo stereotactic ekunze-beam radiation kurapwa uye stereotaxic radiation kurapwa.

• Proton beam radiation Therapy: Proton-beam kurapa rudzi rweakakwira-simba, ekunze radiation kurapwa. Mushini wekurapa nemwaranzi unovavarira nzizi dzemapurotoni (zvidiki, zvisingaonekwe, zvine mutsindo) mumasero ekenza kuvauraya. Rudzi urwu rwekurapa rwunokonzeresa kukuvara kudiki kune hutano huri padyo

• Yemukati radiation kurapwa kunoshandisa radioactive chinhu chakavharirwa mune tsono, mhodzi, waya, kana makateti anoiswa akananga mukati kana padyo nekenza. Iyo inoshandiswa kurapa gomarara munzvimbo dzakaita senge nyinyo, nyini, chibereko, dundira, prostate, musoro, kana mutsipa. Yemukati radiation kurapwa inonzi zvakare brachytherapy, yemukati radiation, yekudyara radiation, kana epakati ma radiation radiation.

Mhando uye huwandu hweradiotherapy kurapwa uye kana ikapihwa zvinoenderana nezera remwana, mhando yerhabdomyosarcoma, imo mumuviri bundu rakatanga, mangani mamota akasara mushure mekuvhiyiwa, uye kana paine bundu mune ma lymph node ari padyo. .

External radiation therapy inowanzo shandiswa kurapa hudiki rhabdomyosarcoma asi mune dzimwe nguva kurapwa kwemwaranzi yemukati kunoshandiswa.

Chemotherapy

Chemotherapy mushonga wekenza unoshandisa mishonga kumisa kukura kwemasero ekenza, kungave nekuuraya maseru kana nekuamisa iwo kubva pakupatsanuka. Kana chemotherapy ikatorwa nemuromo kana kujowa mutsinga kana mhasuru, mishonga inopinda muropa uye inogona kusvika masero emukenza mumuviri wese (systemic chemotherapy). Kana chemotherapy ikaiswa yakanangana necerebrospinal fluid, nhengo, kana dumbu remuviri senge dumbu, iwo madhiragi anonyanya kukanganisa cancer maseru munzvimbo idzodzo (remunharaunda chemotherapy).

Chemotherapy inogona zvakare kupihwa kudzikisa bundu risati ravhiyiwa kuitira kuchengetedza nyama dzakagwinya zvakanyanya sezvinobvira. Izvi zvinonzi neoadjuvant chemotherapy.

Mwana wese anorapwa rhabdomyosarcoma anofanirwa kuwana systemic chemotherapy kudzikisira mukana kenza ichadzokazve. Rudzi rweanticancer mushonga, dhizaini, uye huwandu hwekurapa wakapihwa zvinoenderana nekuti mwana ane njodzi yakadzika, yepakati-njodzi, kana yakanyanya njodzi rhabdomyosarcoma.

Ona Zvinodhaka Zvinotenderwa Rhabdomyosarcoma kuti uwane rumwe ruzivo.

Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

Ichi chidimbu chikamu chinotsanangura kurapwa kuri kuongororwa mumakiriniki ekuedzwa. Zvinogona kusataura nezveese marapirwo matsva ari kuongororwa. Ruzivo nezve kiriniki miedzo inowanikwa kubva kuNCI webhusaiti.

Immunotherapy

Immunotherapy kurapwa kunoshandisa immune system yemurwere kurwisa gomarara. Zvinhu zvinogadzirwa nemuviri kana kugadzirwa murabhoritari zvinoshandiswa kusimudzira, kunongedza, kana kudzorera kudzivirira kwemuviri kurwisa kenza. Rudzi rwekurapa kenza urwu rwunonziwo biologic therapy kana biotherapy.

Kune akasiyana marudzi eunonotherapy:

• Mushonga wekurapa mushonga wekenza unoshandisa chinhu kana boka rezvinhu kukurudzira immune system kuti iwane iro bundu uye riuraye. Kurapa kwekudzivirira kuri kuongororwa kuti irape metastatic rhabdomyosarcoma.

• Immune checkpoint inhibitor therapy inoshandisa immune system yemuviri kuuraya maseru ekenza. Mhando mbiri dze immune checkpoint inhibitors dziri kuongororwa mukurapa kwehucheche rhabdomyosarcoma iyo yadzoka mushure mekurapwa:

• CTLA-4 ipuroteni iri pamusoro peT maseru ayo anobatsira kuchengetedza mhinduro dzemumuviri. CTLA-4 painobatirira kune imwe protein inonzi B7 pane kenza kenza, inomisa iyo T cell kuuraya kenza kenza. CTLA-4 inhibitors inonamira kuCTLA-4 uye inobvumira iwo maseru eT kuuraya maseru ekenza Ipilimumab rudzi rweCTLA-4 inhibitor.

Immune checkpoint inhibitor. Checkpoint mapuroteni, akadai seB7-1 / B7-2 pane antigen-anouya maseru (APC) uye CTLA-4 pane T maseru, anobatsira kuchengetedza mhinduro dzemumuviri. Kana iyo T-cell receptor (TCR) inosunga kune antigen uye makuru histocompatibility complex (MHC) mapuroteni paAPC uye CD28 inosunga kuna B7-1 / B7-2 paAPC, iyo T cell inogona kumisikidzwa. Nekudaro, kusunga kweB7-1 / B7-2 kusvika CTLA-4 kunoita kuti maT cell ari munzvimbo isingashande saka havakwanise kuuraya maseru emota mumuviri (kuruboshwe pani). Kuvhara kusunga kweB7-1 / B7-2 kusvika CTLA-4 ine immune checkpoint inhibitor (anti-CTLA-4 antibody) inobvumira iwo maseru eT kuti ave anoshanda uye kuuraya tumarara maseru (kurudyi pani).

• PD-1 ipuroteni iri pamusoro peT maseru ayo anobatsira kuchengetedza mhinduro dzemumuviri. Kana PD-1 yakanamatira kune imwe protein inonzi PDL-1 pane kenza kenza, inomisa iyo T cell kuuraya kenza kenza. PD-1 inhibitors inonamira kuPDL-1 uye inobvumira iwo maseru eT kuuraya maseru ekenza. Nivolumab uye pembrolizumab ndeye PD-1 inhibitors.

Immune checkpoint inhibitor. Checkpoint mapuroteni, akadai sePD-L1 pane maseru emota uye PD-1 pane T maseru, anobatsira kuchengetedza mhinduro dzemumuviri. Iko kusungwa kwePD-L1 kusvika PD-1 kunoita kuti masero eT arege kuuraya tumarara maseru mumuviri (kuruboshwe pani). Kuvhara kusunga kwePD-L1 kusvika PD-1 ine immune checkpoint inhibitor (anti-PD-L1 kana anti-PD-1) inobvumira iwo maseru eT kuuraya matumbo maseru (kurudyi pani).

Targeted kurapwa

Targeted therapy mhando yekurapa inoshandisa zvinodhaka kana zvimwe zvinhu kurwisa cancer maseru. Kurapa kwakanangidzirwa kunowanzo kukonzera kukuvara kudiki kune maseru akajairwa pane kuita chemotherapy kana radiation. Kune mhando dzakasiyana dzeakanangwa kurapwa.

• mTOR inhibitors vanomisa protein inobatsira maseru kupatsanuka nekurarama. Sirolimus rudzi rweMTOR inhibitor kurapa kuri kudzidziswa mukurapa kwazvino rhabdomyosarcoma.

• Tyrosine kinase inhibitors madiki-mamorekuru madhiragi ayo anodarika nepanhengo yesero uye anoshanda mukati memukenza maseru kuvharira masaini ekuti cancer maseru anoda kukura nekukamurwa. MK-1775 uye cabozantinib-s-malate ari tyrosine kinase inhibitors ari kudzidza mukurapa kwazvino rhabdomyosarcoma.

Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

Kune vamwe varwere, kutora chikamu mumuedzo wekiriniki inogona kunge iri sarudzo yekurapa yakanyanya kunaka. Kliniki miedzo chikamu chekenza tsvagiridzo. Zvemakiriniki miedzo inoitwa kuti uone kana marapirwo matsva egomarara akachengeteka uye achishanda kana zvirinani pane akajairwa kurapwa.

Mazhinji emazuva ano marapirwo akajairwa ekenza akavakirwa pamavambo emakiriniki ekuedzwa. Varwere vanotora chikamu mukuyedzwa kwekiriniki vanogona kuwana kurapwa kwakaringana kana kuve pakati pevekutanga kurapwa kutsva.

Varwere vanotora chikamu mumiedzo yekiriniki zvakare vanobatsira kugadzirisa marapirwo achaitwa kenza mune ramangwana. Kunyangwe kana miedzo yemakiriniki isinga tangire kumarapirwo matsva anoshanda, anowanzo pindura mibvunzo yakakosha uye anobatsira kufambisira mberi kutsvagurudza.

Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kenza kurapwa.

Mimwe miedzo yekiriniki inosanganisira chete varwere vasati vagamuchira kurapwa. Mimwe miedzo yekuedza kurapwa kwevarwere vane kenza haina kuve nani. Kune mamwezve emakiriniki miedzo inoedza nzira nyowani dzekumisa cancer kubva kudzokororazve (kudzoka) kana kudzikisira mhedzisiro yemakenza kurapwa.

Kuedzwa kwemakiriniki kuri kuitika munzvimbo zhinji dzenyika. Ruzivo nezve kiriniki miedzo inotsigirwa neNCI inogona kuwanikwa paNCI yekiriniki miedzo yekutsvaga peji rewebhu. Kliniki miedzo inotsigirwa nemamwe masangano inogona kuwanikwa pane yeClinicalTrials.gov webhusaiti.

Yekutevera-bvunzo inogona kudikanwa.

Mimwe miedzo yakaitwa kuongorora gomarara kana kutsvaga danho rekenza inogona kudzokororwa. Dzimwe bvunzo dzinodzokororwa kuitira kuti vaone kuti kurapa kuri kushanda sei. Sarudzo nezvekuti uenderere mberi, shandura, kana kumisa kurapwa kunogona kunge kuchibva pamhedzisiro yeiyi bvunzo.

Mimwe bvunzo ichaenderera ichiitwa nguva nenguva mushure mekunge kurapwa kwapera. Mhedzisiro yeiyi bvunzo inogona kuratidza kana mamiriro emwana wako achinja kana kana gomarara radzoka (dzoka). Iyi bvunzo dzimwe nguva inonzi yekuteedzera-bvunzo kana kuongorora-kumusoro.

Kurapa Sarudzo dzeMwana Rhabdomyosarcoma

Muchikamu chino

• Pakutanga Isina Kubatwa Kwehucheche Rhabdomyosarcoma

• Refractory kana Yakajairika Yevacheche Rhabdomyosarcoma

Kuti uwane ruzivo nezve marapirwo akanyorwa pazasi, ona iyo Chikamu Sarudzo Yekutarisa Chikamu.

Pakutanga Isina Kubatwa Kwehucheche Rhabdomyosarcoma

Kurapa kwehudiki rhabdomyosarcoma kazhinji kunosanganisira kuvhiya, radiation radiation, uye chemotherapy. Iwo marongero ekuti mishonga iyi inopihwa zvinoenderana nekuti mumuviri imomo ratanga kupi, saizi yebundu, mhando yemota, uye kuti bundu racho rapararira kuma lymph node kana zvimwe zvikamu zvemuviri. Ona iyo Chikamu Chokurapa Sarudzo Yekutarisa chikamu cheichi chidimbu kuti uwane rumwe ruzivo nezve kuvhiya, radiation radiation, uye chemotherapy inoshandiswa kurapa vana vane rhabdomyosarcoma.

Rhabdomyosarcoma yeuropi uye musoro nemutsipa

• Kune mamota europi: Kurapa kunogona kusanganisira kuvhiya kubvisa bundu, radiation radiation, uye chemotherapy.

• Kune mamota emusoro nemutsipa ari mukati kana padyo neziso: Kurapa kunogona kusanganisira chemotherapy uye radiation radiation. Kana bundu rikaramba riripo kana richidzoka mushure mekurapwa nekemotherapy uye radiation radiation, kuvhiya kubvisa ziso uye mamwe matishu akakomberedza ziso angangodiwa.

• Kune mamota emusoro nemutsipa ari padyo nenzeve, mhino, zvitadzo, kana chigadziko chedehenya asi kwete mukati kana padyo neziso: Kurapa kunogona kusanganisira radiation radiation uye chemotherapy.

• Kune mamota emusoro nemutsipa asiri mukati kana padyo neziso uye asiri padyo nenzeve, mhino, zvitadzo, kana chigadziko chedehenya: Kurapa kunogona kusanganisira chemotherapy, radiation radiation, uye kuvhiya kubvisa bundu.

• Kune mamota emusoro nemutsipa asingagone kubviswa nekuvhiya: Kurapa kunogona kusanganisira chemotherapy uye radiation radiation inosanganisira stereotactic muviri radiation radiation.

• Kune mamota eiyo larynx (izwi bhokisi): Kurapa kunogona kusanganisira chemotherapy uye radiation radiation. Kuvhiya kubvisa gurokuru hakuwanzo kuitwa, kuitira kuti izwi risakuvara.

Rhabdomyosarcoma yemaoko kana makumbo

• Chemotherapy inoteverwa nekuvhiya kubvisa bundu. Kana bundu racho risina kubviswa zvachose, kuvhiya kwechipiri kubvisa bundu kunogona kuitwa. Radiation therapy inogona zvakare kupihwa.

• Kune mamota eruoko kana tsoka, radiation radiation uye chemotherapy inogona kupihwa. Bundu harigone kubviswa nekuti rinokanganisa mashandiro eruoko kana rutsoka.

• Lymph node dissection (imwe kana kupfuura ma lymph node anobviswa uye sampuro yetishu inotariswa pasi pe microscope yezviratidzo zvegomarara).

• Kune mamota mune maoko, lymph node padhuze nebundu uye munzvimbo yehapwa inobviswa.

• Kune mapundu mumakumbo, lymph node padhuze nebundu uye munzvimbo yekugomera inobviswa.

Rhabdomyosarcoma yechipfuva, dumbu, kana chiuno

• Kune mamota mubhokisi kana mudumbu (kusanganisira chipfuva madziro kana mudumbu madziro): Kuvhiya (yakafara yemuno kubviswa) kunogona kuitwa. Kana bundu iri rakakura, chemotherapy uye radiation radiation inopihwa kudzikisa bundu risati ravhiyiwa.

• Kune mamota emukati wepelvis: Kuvhiya (yakawandisa yemukati kubviswa) kunogona kuitwa. Kana bundu racho rakakura, chemotherapy inopihwa kudzikisa bundu usati wavhiyiwa. Radiation therapy inogona kupihwa mushure mekuvhiyiwa.

• Kune mapundu eiyo diaphragm: Bhiopsy yebundu rinoteverwa nekemotherapy uye radiation radiation kurapa bundu. Kuvhiya kunogona kuitwa gare gare kubvisa chero maseru egomarara asara.

• Kune mamota eiyo gallbladder kana bile ducts: Bhiopsy yebundu rinoteverwa nekemotherapy uye radiation radiation.

• Pamamota emhasuru kana zvinyama zvakakomberedza anus kana pakati peanhengo uye iyo anus kana gumbo uye anus: Kuvhiya kunoitwa kubvisa zvakanyanya bundu sezvinobvira uye mamwe ma lymph node ari padyo, anoteverwa nekemotherapy uye radiation radiation.

Rhabdomyosarcoma yeitsvo

• Kune mamota eitsvo: Kuvhiya kubvisa zvakanyanya bundu sezvinobvira. Chemotherapy uye radiation radiation inogona zvakare kupihwa.

Rhabdomyosarcoma yedundira kana prostate

• Kune mamota anongori pamusoro pechidzitiro: Kuvhiya (kuwanda kwenzvimbo) kunoitwa.

• Kune mamota eprostate kana dundira (kunze kwekumusoro kwedundira):

• Chemotherapy uye radiation radiation inopihwa kutanga kudzora bundu. Kana masero emukenza akasara mushure memakemikari uye radiation kurapwa, bundu rinobviswa nekuvhiya Kuvhiya kunogona kusanganisira kubviswa kweprostate, chikamu chedundira, kana kupisa kwepamuviri pasina kubviswa kwerece. (Izvi zvinogona kusanganisira kubviswa kwekoloni yepazasi uye dundira. Muvasikana, muromo wechibereko, nyini, mazai, uye node dziri pedyo dzinogona kubviswa).

• Chemotherapy inopiwa kutanga kudzikisa bundu. Kuvhiya kubvisa bundu, asi kwete dundira kana prostate, zvaitwa. Yemukati kana yekunze radiation radiation inogona kupihwa mushure mekuvhiyiwa.

• Kuvhiya kubvisa bundu, asi kwete dundira kana prostate. Yemukati radiation kurapwa kunopihwa mushure mekuvhiyiwa.

Rhabdomyosarcoma yenzvimbo iri padyo nemachende

• Kuvhiya kubvisa testicle uye spermatic tambo. MaLymph node ari kumashure kwedumbu anogona kuongororwa kuti ane gomarara here, kunyanya kana ma "lymph node" akakura kana mwana aine makore gumi kana kudarika.

• Radiation kurapwa kunogona kupihwa kana bundu risingakwanise kubviswa zvachose nekuvhiyiwa.

Rhabdomyosarcoma yeiyo vulva, nyini, chibereko, cervix, kana ovary

• Kune mamota emukadzi uye emukadzi: Kurapa kunogona kusanganisira chemotherapy inoteverwa nekuvhiya kubvisa bundu. Yemukati kana yekunze radiation radiation inogona kupihwa mushure mekuvhiyiwa.

• Kune mamota echibereko: Kurapa kunogona kusanganisira chemotherapy pamwe kana isina radiation radiation. Dzimwe nguva kuvhiya kungangodikanwa kubvisa chero maseru egomarara asara.

• Kune mamota emuromo wechibereko: Kurapa kunogona kusanganisira chemotherapy inoteverwa nekuvhiya kubvisa chero bundu rasara.

• Kune mamota eovari: Kurapa kunogona kusanganisira chemotherapy inoteverwa nekuvhiya kubvisa chero bundu rasara.

Metastatic rhabdomyosarcoma

Kurapa, senge chemotherapy, radiation radiation, kana kuvhiya kubvisa bundu, kunopihwa kunzvimbo iyo bundu rakatanga kuumbwa. Kana gomarara rapararira kuuropi, musana, kana mapapu, kurapwa kwemwaranzi kunogona kupihwa kunzvimbo dzakapararira gomarara.

Iyi inotevera kurapwa iri kuongororwa kune metastatic rhabdomyosarcoma:

• Kuongororwa kwekiriniki ye immunotherapy (mushonga wekudzivirira).

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Refractory kana Yakajairika Yevacheche Rhabdomyosarcoma

Sarudzo dzekurapa dzinodzora kana dzokororo yehudiki rhabdomyosarcoma yakavakirwa pazvinhu zvakawanda, kusanganisira kuti mumuviri kenza yadzoka kupi, nderupi rudzi rwekurapwa kwaive nemwana kare, nezvinodiwa zvemwana.

Kurapa kweanopokana kana anowanzoitika rhabdomyosarcoma inogona kusanganisira imwe kana yakawanda yeanotevera:

• Kuvhiya.

• Radiation kurapa.

• Chemotherapy.

• Kuongororwa kwekiriniki yekurapa kwakanangwa kana immunotherapy (sirolimus, ipilimumab, nivolumab, kana pembrolizumab).

• Kuongororwa kwekiriniki kweakanangwa kurapwa ne tyrosine kinase inhibitor (MK-1775 kana cabozantinib-s-malate) uye chemotherapy.

• Kuongororwa kwekiriniki kunoongorora muyenzaniso wemota yemurwere kune mamwe magene ekuchinja. Rudzi rwekurapa kwakanangwa kuchapihwa kumurwere kunoenderana nerudzi rwechinjo yemajini.

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Kuti Udzidze Zvakawanda Pamusoro Pehucheche Rhabdomyosarcoma

Kuti uwane rumwe ruzivo kubva kuNational Cancer Institute nezvehudiki rhabdomyosarcoma, ona zvinotevera:

• Tissue Nyoro Sarcoma Peji Peji

• Computed Tomography (CT) Scans uye Cancer

• Zvinodhaka Zvinotenderwa Rhabdomyosarcoma

• Targeted Cancer Therapies

Kuti uwane rumwe ruzivo rwegomarara rehucheche uye zvimwe zvecancer zviwanikwa, ona zvinotevera:

• Nezve Kenza

• Cancers Yevacheche

• Kurapa Kutsvaga Kwevana Cancer Buda Disclaimer

• Mahedhi Ekupedzisira Ekurapwa kweKenza Yevacheche

• Vechidiki uye Vechidiki Vakuru vane Cancer

• Vana vane Cancer: Nhungamiro Yevabereki

• Kenza muVana neVachiri kuyaruka

• Stage

• Kurarama neCancer

• Mibvunzo Yekubvunza Wako Chiremba nezveCancer

• Kune Vakapona uye Vanotarisira