Types/myeloproliferative/patient/myelodysplastic-treatment-pdq

Myelodysplastic Syndromes Kurapa (®) -Patient Shanduro

General Ruzivo nezve Myelodysplastic Syndromes

PFUNGWA DZINOKOSHA

• Myelodysplastic syndromes iboka remakenza umo masero eropa asina kuchena mumongo wemapfupa haakure kana kuve masero eropa ane hutano.

• Mhando dzakasiyana dzemyelodysplastic syndromes dzinoonekwa zvichienderana nekumwe kuchinja mumasero eropa uye mwongo wefupa.

• Zera uye kurapwa kwekare nekemotherapy kana radiation radiation inokanganisa njodzi yeiyo myelodysplastic syndrome.

• Zviratidzo uye zviratidzo zveiyo myelodysplastic syndrome zvinosanganisira kupfupika kwekufema uye kunzwa kuneta.

• Kuyedza kunoongorora ropa nemwongo wemapfupa kunoshandiswa kuona (kuwana) uye kuongorora myelodysplastic syndromes.

• Zvimwe zvinhu zvinokanganisa kufungidzira uye sarudzo dzekurapa.

Myelodysplastic syndromes iboka remakenza umo masero eropa asina kuchena mumongo wemapfupa haakure kana kuve masero eropa ane hutano.

Mune munhu ane hutano, mwongo wemapfupa unoita maseru masero eropa (maseru asina kukura) anova masero eropa akakura nekufamba kwenguva.

Anatomy yebhonzo. Bhonzo rinoumbwa necompact bone, spongy bone, uye mwongo wefupa. Compact bone rinoumba chikamu chekunze chepfupa. Spongy bone rinowanikwa zvakanyanya kumagumo emabhonzo uye rine mutsvuku. Bhonzo remapfupa rinowanikwa pakati pemapfupa mazhinji uye rine tsinga zhinji dzeropa. Kune mhando mbiri dzemongo wemapfupa: tsvuku uye yero. Mutsvuku mutsvuku une masero eropa anogona kuve masero matsvuku eropa, machena masero eropa, kana maplatelet. Yero mwongo inogadzirwa kazhinji yemafuta.

Sero reropa rinogona kuva lymphoid stem cell kana myeloid stem cell. Lymhoid stem cell rinova jena reropa jena. Iyo myeloid stem sero inova imwe yemhando nhatu dzemasero eropa akura:

• Masero matsvuku eropa anotakura okisijeni nezvimwe zvinhu kumatishu ese emuviri.

• Maplatelet ayo anogadzira ropa kuwacha kubuda ropa.

• Masero machena eropa anorwisa hutachiona nezvirwere.

Ropa masero kukura. Sero reropa rinopinda nematanho akati wandei kuti riite tsvuku reropa, platelet, kana chena reropa.

Mune murwere ane myelodysplastic syndrome, masero eropa (maseru asina kukura) haaite masero matsvuku eropa, masero machena eropa, kana maplatelet mumongo wepfupa. Aya masero eropa asina kusimba, anonzi kuputika, haashande nenzira yaanofanirwa uye anogona kufa mumongo wemapfupa kana achangopinda muropa. Izvi zvinosiya nzvimbo shoma yemasero machena ane hutano, masero matsvuku eropa, uye maplatelet kuti agadzire mumongo wepfupa. Kana paine mashoma masero eropa ane hutano, hutachiona, kupererwa neropa, kana kubuda ropa nyore zvinogona kuitika.

Mhando dzakasiyana dzemyelodysplastic syndromes dzinoonekwa zvichienderana nekumwe kuchinja mumasero eropa uye mwongo wefupa.

• Refractory anemia: Kune mashoma masero matsvuku eropa muropa uye murwere ane anemia. Huwandu hwemasero machena eropa uye maplatelet akajairika.

• Refractory anemia ine mhete sideroblasts: Kune mashoma masero matsvuku eropa muropa uye murwere ane anemia. Masero matsvuku eropa ane iron yakawandisa mukati mekamuri. Huwandu hwemasero machena eropa uye maplatelet akajairika.

• Refractory anemia ine yakawandisa kuputika: Kune mashoma maseru matsvuku eropa muropa uye murwere ane anemia. Zvishanu muzana kusvika 19% yemasero ari mumongo wemapfupa anoputika. Ikoko zvakare kunogona kuve neshanduko kumasero machena eropa uye maplatelet. Refractory anemia ine yakawandisa kuputika inogona kufambira mberi kune yakaoma myeloid leukemia (AML). Ona iyo Yevakuru Yakakura Myeloid Leukemia Kurapa pfupiso kuti uwane rumwe ruzivo.

• Refractory cytopenia ine multilineage dysplasia: Kune mashoma mashoma emhando mbiri dzemasero eropa (masero matsvuku eropa, maplatelet, kana machena masero eropa). Pasina pasi pe5% yemasero ari mumongo wemapfupa anoputika uye isingasviki 1% yemasero muropa anoputika. Kana masero matsvuku eropa akabatwa, anogona kunge aine imwe iron. Refractory cytopenia inogona kufambira mberi kusvika kune yakaoma myeloid leukemia (AML).

• Refractory cytopenia ine unilineage dysplasia: Kune mashoma kwazvo erudzi rweropa (masero matsvuku eropa, maplatelet, kana machena masero eropa). Pane shanduko mu10% kana anopfuura mamwe maviri marudzi emasero eropa. Pasina pasi pe5% yemasero ari mumongo wemapfupa anoputika uye isingasviki 1% yemasero muropa anoputika.

• Unclassifiable myelodysplastic syndrome: Huwandu hwekuputika mumapfupa neropa zvakajairika, uye chirwere hachisi chimwe cheimwe myelodysplastic syndromes.

• Myelodysplastic syndrome inosanganisirwa neyega del (5q) chromosome kujairika: Kune mashoma maseru matsvuku eropa muropa uye murwere ane anemia. Pasina pasi pe5% yemasero ari mumongo wefupa uye neropa zvinoputika. Iko kune chaiko shanduko mune chromosome.

• Chisingaperi myelomonocytic leukemia (CMML): Ona pfupiso ye paMyelodysplastic / Myeloproliferative Neoplasms Kurapa kuti uwane rumwe ruzivo.

Zera uye kurapwa kwekare nekemotherapy kana radiation radiation inokanganisa njodzi yeiyo myelodysplastic syndrome.

Chero chipi zvacho chinowedzera njodzi yako yekuwana chirwere chinonzi njodzi chinhu. Kuva nenjodzi hazvireve kuti iwe unowana chirwere; kusava nenjodzi hazvireve kuti hauzowani chirwere. Taura nachiremba wako kana iwe uchifunga kuti ungave uri panjodzi. Njodzi zvinhu zvemyelodysplastic syndromes zvinosanganisira zvinotevera:

• Kurapa kwekare nekemotherapy kana radiation radiation yekenza.

• Kuoneswa pachena kune mamwe makemikari, anosanganisira utsi hwefodya, mishonga yezvipembenene, mafetiraiza, uye zvinonyungudutsa zvakaita sebenzene.

• Kufumurwa kune simbi dzinorema, senge mercury kana lead.

Chikonzero chemyelodysplastic syndromes mune vazhinji varwere hachizivikanwe.

Zviratidzo uye zviratidzo zveiyo myelodysplastic syndrome zvinosanganisira kupfupika kwekufema uye kunzwa kuneta.

Myelodysplastic syndromes kazhinji haakonzere zviratidzo zvekutanga kana zviratidzo. Vanogona kuwanikwa panguva yekuongororwa kweropa. Zviratidzo nezviratidzo zvinogona kukonzerwa ne myelodysplastic syndromes kana nemamwe mamiriro. Tarisa nachiremba wako kana iwe uine chero chinotevera:

• Kufema kwekufema.

• Kuneta kana kunzwa kuneta.

• Kuva neganda rakareruka kupfuura zvakajairwa.

• Kupwanya kuri nyore kana kubuda ropa.

• Petechiae (yakati sandara, inongedzera mavara pasi peganda rinokonzerwa nekubuda ropa).

Kuyedza kunoongorora ropa nemwongo wemapfupa kunoshandiswa kuona (kuwana) uye kuongorora myelodysplastic syndromes.

Iyi inotevera bvunzo uye maitiro anogona kushandiswa:

• Kuongorora kwepanyama uye nhoroondo: Kuongororwa kwemuviri kutarisa zviratidzo zvehutano, kusanganisira kuongorora zviratidzo zvehosha, zvakadai semapundu kana chero chinhu chinoratidzika sechisina kujairika. Nhoroondo yemaitiro ehutano hwemurwere uye kurwara kwakapfuura uye kurapwa kuchatorwawo.

• Yakazara huwandu hweropa (CBC) nemusiyano: Maitiro umo muyenzaniso weropa unodhonzwa nekuongororwa zvinotevera:

Huwandu hwemasero matsvuku eropa nemaplatelet.

• Nhamba uye mhando yemasero machena eropa.

• Huwandu hwehemoglobin (protein inotakura oxygen) mumasero matsvuku eropa.

• Chikamu chemuenzaniso weropa chakaumbwa nemasero matsvuku eropa.

Yakazara kuverenga ropa (CBC). Ropa rinounganidzwa nekupinza tsono mutsinga uye richiita kuti ropa riyerere muhubhu. Muenzaniso weropa unotumirwa murabhoritari uye masero matsvuku eropa, masero machena eropa, uye maplatelet anoverengwa. Iyo CBC inoshandiswa kuyedza, kuongorora, uye kuongorora akawanda mamiriro akasiyana.

• Peripheral ropa smear: Maitiro umo muyenzaniso weropa unotariswa shanduko munhamba, mhando, chimiro, uye saizi yemasero eropa uye nesimbi yakawandisa mumasero matsvuku eropa.

• Kuongorora kweCytogenetic: Kuongororwa kwerabhoritari umo ma chromosomes emasero mune imwe sampu yemongo kana ropa anoverengwa uye kuongororwa chero shanduko, sekutyorwa, kushaikwa, kurongedzwa patsva, kana mamwe ma chromosomes. Shanduko mune mamwe ma chromosomes inogona kunge iri chiratidzo checancer. Kuongorora kweCytogenetic kunoshandiswa kubatsira kuongorora cancer, kuronga kurapwa, kana kuona kuti kurapa kuri kushanda sei.

• Ropa kemisitiri zvidzidzo: Maitiro ekuti muyero weropa unotariswa kuyera huwandu hwezvimwe zvinhu, senge vhitamini B12 uye folate, inoburitswa muropa nenhengo uye nyama munyama. Chinhu chisina kujairika (chakakwirira kana chakaderera pane zvakajairwa) chiyero chechinhu chinogona kunge chiri chiratidzo chechirwere.

• Bone marrow aspiration uye biopsy: Kubviswa kwemongo wefupa, ropa, uye chidimbu chefupa nekuisa tsono isina mhango muhudyu kana pfupa rechipfuva. Nyanzvi yezvirwere anoona pfupa, ropa, uye pfupa pasi pe microscope kutsvaga masero asina kujairika.

Bone marora chishuwo uye biopsy. Mushure mekunge nzvimbo diki yeganda yave nechiveve, tsono yemongo wemapfupa inoiswa mupfupa rehudyu remurwere. Samples reropa, bhonzo, uye mwongo wemapfupa zvinobviswa kuti zviongororwe pasi pe microscope.

Iyi bvunzo inotevera inogona kuitwa pane sampuro yetishu inobviswa.

• Immunocytochemistry: Kuongororwa kwerabhoritari inoshandisa masoja ekudzivirira mamwe maantigen (mamaki) mune imwe sampuro yemongo wemurwere. Masoja ekudzivirira chirwere anowanzo sunganidzwa ne enzyme kana dhayi ye fluorescent. Mushure mekunge maantibodies akasunga kune antigen mune muyero wemasero emurwere, iyo enzyme kana dhayi inoitwa, uye antigen inogona kuzoonekwa pasi pe microscope. Rudzi urwu rweyedzo runoshandiswa kubatsira kuongorora gomarara uye kutaurira musiyano uripo pakati peyelodysplastic syndromes, leukemia, uye mamwe mamiriro.

• Immunophenotyping: Kuongororwa kwerabhoritari inoshandisa masoja ekudzivirira kenza maseru zvichibva pamhando dzemaantigen kana mamaki ari pamusoro pemasero. Muedzo uyu unoshandiswa kubatsira kuongorora chaiwo marudzi eleukemia uye kumwe kusawirirana kweropa.

• Kuyerera cytometry: Kuongororwa kwerabhoritari kunoyera huwandu hwamasero mune imwe sampuro, muzana yemasero ehupenyu mune imwe sampuro, uye mamwe maitiro emaseru, senge saizi, chimiro, uye kuvepo kwethumba (kana zvimwe) mamaki pane sero pamusoro. Masero kubva pamuenzaniso weropa remurwere, mwongo wemapfupa, kana zvimwe zvinyama zvakasvibiswa nedhayi re fluorescent, rakaiswa mune mvura, uye ndokuzopfuura rimwe panguva kuburikidza nemwenje wechiedza. Mhedzisiro yekubvunzurudza inoenderana nekuti maseru aive akasvibiswa neiyo fluorescent dhayi anoita sei padanda rechiedza. Uyu muedzo unoshandiswa kubatsira kuongorora uye kubata mamwe marudzi ekenza, senge leukemia uye lymphoma.

• FISH (fluorescence in situ hybridization): Kuedzwa kwerabhoritari kunoshandiswa kutarisa uye kuverenga majeni kana ma chromosomes mumasero nematukisi. Zvidimbu zveDNA zvine dhayi ye fluorescent zvinogadzirwa murabhoritari uye zvinowedzerwa kune imwe sampuli yemasero emurwere kana zvinyama. Kana zvidimbu izvi zvakavezwa zveDNA zvonamatira kune mamwe mageneti kana nzvimbo dzekromosomes mumuenzaniso, dzinovhenekera kana dzatariswa pasi pefluorescent microscope. Chiyero cheFISH chinoshandiswa kubatsira kuongorora kenza uye kubatsira kuronga kurapwa.

Zvimwe zvinhu zvinokanganisa kufungidzira uye sarudzo dzekurapa.

Kufungidzira (mukana wekupora) uye sarudzo dzekurapa dzinoenderana nezvinotevera:

• Huwandu hwekuputika maseru mumongo wemapfupa.

• Kunyangwe imwe kana mamwe marudzi emasero eropa akanganiswa.

• Kunyangwe murwere ane zviratidzo kana zviratidzo zvekushaya ropa, kubuda ropa, kana hutachiona.

• Kunyangwe murwere aine yakaderera kana yakanyanya njodzi yeleukemia.

• Dzimwe shanduko muma chromosomes.

• Kunyangwe iyo myelodysplastic syndrome yakaitika mushure memakemikari ekurapa kana radiation radiation yekenza.

• Zera uye hutano huzhinji hwemurwere.

Kurapa Sarudzo Kuongorora

PFUNGWA DZINOKOSHA

• Kune mhando dzakasiyana dzekurapa kwevarwere vane myelodysplastic syndromes.

• Kurapa kweiyo myelodysplastic syndromes kunosanganisira kuchengetedzwa kwekutsigira, kurapwa kwezvinodhaka, uye stem cell transplantation.

• Mhando mitatu yekurapa kwakajairika inoshandiswa:

• Kutsigira kutarisirwa

• Kurapa kwezvinodhaka

• Chemotherapy ne stem cell yekuisa

• Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

• Kurapa kwemyelodysplastic syndromes kunogona kukonzera mhedzisiro.

• Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

• Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kurapwa.

• Yekutevera-bvunzo inogona kudikanwa.

Kune mhando dzakasiyana dzekurapa kwevarwere vane myelodysplastic syndromes.

Mhando dzakasiyana dzekurapa dzinowanikwa kune varwere vane myelodysplastic syndromes. Mamwe marapirwo akajairwa (iko kurapwa kwazvino kwashandiswa), uye kumwe kuedzwa mumakiriniki ekuedzwa A kurapwa kiriniki kuyedzwa chidzidzo chekutsvaga chakaitirwa kubatsira kuvandudza marapirwo azvino kana kuwana ruzivo marapirwo matsva evarwere vane gomarara. Kana kiriniki miedzo ikaratidza kuti kurapwa kutsva kuri nani pane kwese kurapwa, kurapwa kutsva kunogona kuve kwakajairwa kurapwa. Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki. Mimwe miedzo yekiriniki yakavhurwa chete kune varwere vasina kutanga kurapwa.

Kurapa kweiyo myelodysplastic syndromes kunosanganisira kuchengetedzwa kwekutsigira, kurapwa kwezvinodhaka, uye stem cell transplantation.

Varwere vane myelodysplastic syndrome vane zviratidzo zvinokonzerwa nekuderera kweropa huwandu vanopihwa rubatsiro rwekutsigira kubvisa zviratidzo nekuvandudza hupenyu hwehupenyu. Kurapa kwezvinodhaka kunogona kushandiswa kunonoka kufambira mberi kwechirwere. Vamwe varwere vanogona kurapwa pamwe nehasha kurapwa ne chemotherapy inoteverwa ne stem cell kuisirwa vachishandisa masero emidzi kubva kune anopa.

Mhando mitatu yekurapa kwakajairika inoshandiswa:

Kutsigira kutarisirwa

Kuchengetedzwa kunopihwa kudzikisira matambudziko anokonzerwa nechirwere kana kurapwa kwacho. Kuchengeta kwekutsigira kunogona kusanganisira zvinotevera:

• Kurapa kwekuwedzera

Transfusion therapy (kuwedzerwa ropa) inzira yekupa masero matsvuku eropa, masero machena eropa, kana maplatelet kutsiva masero eropa akaparadzwa nechirwere kana kurapwa. Kuisirwa masero matsvuku eropa kunopihwa kana iyo tsvuku masero eropa kuverenga yakaderera uye zviratidzo kana zviratidzo zvekushaya ropa, sekufema kwekufema kana kunzwa kuneta zvakanyanya, kunoitika. Kuiswa kweplatelet kunowanzo kupihwa kana murwere achibuda ropa, ari kuita maitiro anogona kukonzera kubuda ropa, kana kana iyo platelet count yakanyanya kuderera.

Varwere vanogashira kuwedzerwa masero eropa kuwedzerwa vanogona kuve nekukuvara kwenyama uye nhengo kunokonzerwa nekuwedzera kwesimbi. Varwere ava vanogona kurapwa nesimbi chelation kurapa kubvisa iyo yakawedzera iron kubva muropa.

• Erythropoiesis-inosimudzira vamiririri

Erythropoiesis-inosimudzira vamiririri (ESAs) inogona kupihwa kuwedzera huwandu hwesero tsvuku dzeropa dzakagadzirwa nemuviri uye kudzikisira mhedzisiro yeanemia. Dzimwe nguva granulocyte koloni-inosimudzira chinhu (G-CSF) inopihwa nemaESA kubatsira kurapwa kushanda zvirinani.

• Mishonga inorwisa mabhakitiriya

Mishonga inorwisa mabhakitiriya inogona kupihwa kurwisa hutachiona.

Kurapa kwezvinodhaka

• Lenalidomide

Varwere vane myelodysplastic syndrome inosanganisirwa neyega del (5q) chromosome kusagadzikana avo vanoda kuwedzerwa kuwedzerwa kweropa masero eropa vanogona kurapwa nelenalidomide. Lenalidomide inoshandiswa kudzikisa kudiwa kwekuwedzerwa kweropa maseru.

• Immunosuppressive kurapa

Antithymocyte globulin (ATG) inoshanda kudzvinyirira kana kushomeka immune system. Iyo inoshandiswa kudzikisira kudiwa kwekuwedzerwa kweropa masero eropa.

• Azacitidine uye decitabine

Azacitidine uye decitabine zvinoshandiswa kurapa myelodysplastic syndromes nekuuraya masero ari kupatsanuka nekukurumidza. Ivo zvakare vanobatsira magene anobatanidzwa mukukura kwemasero kushanda nenzira yavanofanirwa kuita. Kurapa neAzacitidine uye decitabine kunogona kunonoka kufambira mberi kwemyelodysplastic syndromes kune acute myeloid leukemia.

• Chemotherapy inoshandiswa muacute myeloid leukemia (AML)

Varwere vane myelodysplastic syndrome uye yakakwira nhamba yemapfupa emapfupa avo vane njodzi huru yeacute leukemia. Vanogona kurapwa neiyo imwechete chemotherapy regimen inoshandiswa mune varwere vane acute myeloid leukemia.

Chemotherapy ne stem cell yekuisa

Chemotherapy inopihwa kuuraya cancer maseru. Masero ane hutano, kusanganisira masero anogadzira ropa, anoparadzwa nekenza kurapwa. Stem cell transplant kurapwa kwekutsiva maseru anogadzira ropa. Masero emashizha (masero eropa asina kusimba) anobviswa muropa kana mwongo wemapfupa emurwere kana mupi uye anoomeswa nechando. Mushure mekunge murwere apedza chemotherapy, maseru akachengetwa anonyungudutswa uye ndokudzoserwa kumurwere kuburikidza nekumukiswa. Aya akadzikiswa maseru emadzinde anokura kuita (uye kudzoreredza) masero eropa emuviri.

Iyi kurapwa inogona kusashanda zvakare kune varwere vane myelodysplastic syndrome yakakonzerwa nekupfuura kurapwa kwekenza

Stem cell kuisirwa. (Nhanho 1): Ropa rinotorwa kubva mutsinga iri muruoko rweanopa. Murwere kana mumwe munhu angave ari mupi. Ropa rinoyerera nemuchina unobvisa masero emadzinde. Ipapo iro ropa rinodzoserwa kune anenge apa kuburikidza netsinga iri mune rumwe ruoko. (Nhanho 2): Murwere anogamuchira chemotherapy kuuraya masero anogadzira ropa. Murwere anogona kupihwa radiation radiation (isina kuratidzwa). (Nhanho 3): Murwere anogamuchira masero emadzinde kuburikidza nekateti yakaiswa mumudziyo weropa muchipfuva.

Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

Ruzivo nezve kiriniki miedzo inowanikwa kubva kuNCI webhusaiti.

Kurapa kwemyelodysplastic syndromes kunogona kukonzera mhedzisiro.

Kuti uwane ruzivo nezve mhedzisiro inokonzerwa nekurapwa kwegomarara, ona yedu Side Mhedzisiro peji.

Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

Kune vamwe varwere, kutora chikamu mumuedzo wekiriniki inogona kunge iri sarudzo yekurapa yakanyanya kunaka. Kliniki miedzo chikamu chekenza tsvagiridzo. Zvemakiriniki miedzo inoitwa kuti uone kana marapirwo matsva egomarara akachengeteka uye achishanda kana zvirinani pane akajairwa kurapwa.

Mazhinji emazuva ano marapirwo akajairwa ekenza akavakirwa pamavambo emakiriniki ekuedzwa. Varwere vanotora chikamu mukuyedzwa kwekiriniki vanogona kuwana kurapwa kwakaringana kana kuve pakati pevekutanga kurapwa kutsva.

Varwere vanotora chikamu mumiedzo yekiriniki zvakare vanobatsira kugadzirisa marapirwo achaitwa kenza mune ramangwana. Kunyangwe kana miedzo yemakiriniki isinga tangire kumarapirwo matsva anoshanda, anowanzo pindura mibvunzo yakakosha uye anobatsira kufambisira mberi kutsvagurudza.

Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kurapwa.

Mimwe miedzo yekiriniki inosanganisira chete varwere vasati vagamuchira kurapwa. Mimwe miedzo yekuedza kurapwa kwevarwere vane kenza haina kuve nani. Kune mamwezve emakiriniki miedzo inoedza nzira nyowani dzekumisa cancer kubva kudzokororazve (kudzoka) kana kudzikisira mhedzisiro yemakenza kurapwa.

Kuedzwa kwemakiriniki kuri kuitika munzvimbo zhinji dzenyika. Ruzivo nezve kiriniki miedzo inotsigirwa neNCI inogona kuwanikwa paNCI yekiriniki miedzo yekutsvaga peji rewebhu. Kliniki miedzo inotsigirwa nemamwe masangano inogona kuwanikwa pane yeClinicalTrials.gov webhusaiti.

Yekutevera-bvunzo inogona kudikanwa.

Mimwe miedzo yakaitwa kuongorora gomarara kana kutsvaga danho rekenza inogona kudzokororwa. Dzimwe bvunzo dzinodzokororwa kuitira kuti vaone kuti kurapa kuri kushanda sei. Sarudzo nezvekuti uenderere mberi, shandura, kana kumisa kurapwa kunogona kunge kuchibva pamhedzisiro yeiyi bvunzo.

Mimwe bvunzo ichaenderera ichiitwa nguva nenguva mushure mekunge kurapwa kwapera. Mhedzisiro yeiyi bvunzo inogona kuratidza kana mamiriro ako achinja kana kana gomarara radzoka (dzoka). Iyi bvunzo dzimwe nguva inonzi yekuteedzera-bvunzo kana kuongorora-kumusoro.

Kurapa Sarudzo dzeMyelodysplastic Syndromes

Kuti uwane ruzivo nezve marapirwo akanyorwa pazasi, ona iyo Chikamu Sarudzo Yekutarisa Chikamu.

Standard Kurapa Sarudzo dzeMyelodysplastic Syndromes

Maitiro ekurapa akasarudzika emyelodysplastic syndromes anosanganisira:

• Kutsigira kuchengetedza nechero chimwe kana zvimwe zvinotevera.

• Kurapa kwekuwedzera.

• Erythropoiesis-inosimudzira vamiririri.

• Mishonga inorwisa mabhakitiriya.

• Kurapa kunonoka kufambira mberi kune yakaoma myeloid leukemia (AML):

• Lenalidomide.

• Immunosuppressive kurapa.

• Azacitidine uye decitabine.

• Chemotherapy inoshandiswa muacute myeloid leukemia.

• Chemotherapy ne stem cell yekuisa.

Kurapa kweTherapi-Yakabatana neMyeloid Neoplasms

Varwere vakarapwa munguva yakapfuura nekemotherapy kana radiation radiation vanogona kukura myeloid neoplasms ane hukama neiyo kurapa. Kurapa sarudzo kwakafanana kune mamwe myelodysplastic syndromes.

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Kurapa Sarudzo dzeKudzokazve kana Kufuridzira Myelodysplastic Syndromes

Kuti uwane ruzivo nezve marapirwo akanyorwa pazasi, ona iyo Chikamu Sarudzo Yekutarisa Chikamu.

Iko hakuna kurapwa kwakajairika kweanodzora kana kudzokazve myelodysplastic syndromes. Varwere vane gomarara risingapindure pakurapwa kana vakadzoka mushure mekurapwa vangangoda kutora chikamu mukuyedzwa kwekiriniki.

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Kuti udzidze Zvakawanda Nezve Myelodysplastic Syndromes

Kuti uwane rumwe ruzivo kubva kuNational Cancer Institute nezve myelodysplastic syndromes, ona zvinotevera:

• Ropa-Richigadzira Stem Cell Inoshandura

Kuti uwane ruzivo rwekenza uye zvimwe zviwanikwa kubva kuNational Cancer Institute, ona zvinotevera:

• Nezve Kenza

• Stage

• Chemotherapy uye Iwe: Tsigiro Yevanhu Vane Kenza

• Radiation Therapy uye Iwe: Rutsigiro rweVanhu Vane Kenza

• Kurarama neCancer

• Mibvunzo Yekubvunza Wako Chiremba nezveCancer

• Kune Vakapona uye Vanotarisira

• Nezve Iyi Pfupiso