Types/midline/patient-child-midline-tract-carcinoma-treatment-pdq

Yechidiki Midline Tract Carcinoma ine NUT Gene Shanduko Kurapa (®) -Patient Shanduro

Ruzivo Ruzhinji Nezve Mwana Midline Tract Carcinoma

PFUNGWA DZINOKOSHA

• Udiki midline turakiti carcinoma chirwere umo mune yakaipa (gomarara) maseru anoumba mune yekufema turakiti kana dzimwe nzvimbo pamwe nepakati pemuviri.

• Midline tract carcinoma dzimwe nguva inokonzerwa neshanduko yeNUT gene.

• Zviratidzo nezviratidzo zve midline turakiti carcinoma hazvina kufanana mumwana wese.

• Kuyedza kunoongorora muviri kunoshandiswa kubatsira kutsvaga (kuwana) uye kuongorora midline turakiti carcinoma.

• Midline tract carcinoma inokura uye inopararira nekukurumidza.

Udiki midline turakiti carcinoma chirwere umo mune yakaipa (gomarara) maseru anoumba mune yekufema turakiti kana dzimwe nzvimbo pamwe nepakati pemuviri.

Nzira yekufema inoumbwa nemhino, huro, larynx, trachea, bronchi, nemapapu. Midline tract carcinoma inogona zvakare kuumba mune dzimwe nzvimbo pamwe nepakati pemuviri, senge thymus, iyo nzvimbo iri pakati pemapapu, rwatata, chiropa, uye dundira.

Midline tract carcinoma dzimwe nguva inokonzerwa neshanduko yeNUT gene.

Midline tract carcinoma inokonzerwa neshanduko mune chromosome. Sero rega rega mumuviri rine DNA (magene anochengeterwa mukati memachromosomes) anotonga masero anotaridzika uye maitiro Midline tract carcinoma inogona kuumba kana chikamu cheDNA kubva kuchromosome 15 (inonzi iyo NUT gene) inosangana neDNA kubva kune imwe chromosome.

Zviratidzo nezviratidzo zve midline turakiti carcinoma hazvina kufanana mumwana wese.

Zviratidzo nezviratidzo zve midline turakiti carcinoma zvinoenderana nekenza kenza mumuviri.

Kuyedza kunoongorora muviri kunoshandiswa kubatsira kutsvaga (kuwana) uye kuongorora midline turakiti carcinoma.

Iyo bvunzo inoshandiswa kuona uye kuongorora midline turakiti carcinoma zvinoenderana nekenza kenza mumuviri uye inogona kusanganisira zvinotevera:

• Kuongorora kwemuviri uye nhoroondo yehutano: Kuongororwa kwemuviri kutarisa zviratidzo zvehutano, kusanganisira kuongorora zviratidzo zvehosha, zvakadai semapundu kana chero chinhu chinoratidzika sechisina kujairika. Nhoroondo yemaitiro ehutano hwemurwere uye kurwara kwakapfuura uye kurapwa kuchatorwawo.

• Chest x-ray: X-ray yechifuva. X-ray imhando yesimba remagetsi rinogona kupfuura nemuviri uye kupinda mufirimu, richiita mufananidzo wenzvimbo dziri mukati memuviri.

• MRI (magnetic resonance imaging): Maitiro anoshandisa magineti, masaisai eredhiyo, uye komputa kugadzira yakateedzana mifananidzo yakajeka yenzvimbo dzemuviri, senge musoro nemutsipa. Iyi nzira inonziwo nyukireya magnetic resonance imaging (NMRI).

• CT scan (CAT scan): Maitiro anoita akateedzana emifananidzo yakajeka yenzvimbo dziri mukati memuviri yakatorwa kubva kumakona akasiyana. Mifananidzo yacho inogadzirwa nekombuta yakabatana neiyo x-ray muchina. Dhayi inogona kuiswa jekiseni kana kumedzwa kubatsira nhengo kana zvinyama kuratidza zvakajeka. Iyi nzira inonziwo computed tomography, computerized tomography, kana komputa axial tomography.

Computed tomography (CT) scan yemusoro nemutsipa. Mwana akarara patafura inotsvedza kuburikidza neCT scanner, iyo inotora x-ray mifananidzo yemukati memusoro nemutsipa.

• Biopsy: Kubviswa kwemasero kuitira kuti vagone kutariswa pasi pemaikorosikopu nachiremba wepachirwere kuti aone zviratidzo zvegomarara.

Muedzo unotevera unogona kuitwa pamuenzaniso wemasero akabviswa:

• Immunohistochemistry: Kuongororwa kwerabhoritari inoshandisa masoja ekudzivirira mamwe maantigen (mamaki) mune imwe sampuro yetishu yemurwere. Masoja ekudzivirira chirwere anowanzo sunganidzwa ne enzyme kana dhayi ye fluorescent. Mushure mekunge maantibodies akasunga kune yakasarudzika antigen mune yeiyo sampuli, iyo enzyme kana dhayi inoitwa, uye iyo antigen inogona kuzoonekwa pasi pe microscope. Rudzi urwu rweyedzo runoshandiswa kubatsira kuongorora gomarara uye kubatsira kutaurira imwe mhando yekenza kubva kune imwe mhando yegomarara.

• Kuongorora kweCytogenetic: Kuongororwa kwerabhoritari umo ma chromosomes emaseru mune imwe sampu yemongo, ropa, bundu, kana zvimwe zvinyama zvinoverengerwa uye kuongororwa chero shanduko, dzakadai sekutyoka, kushaikwa, kugadziriswazve, kana mamwe ma chromosomes. Shanduko mune mamwe ma chromosomes inogona kunge iri chiratidzo checancer. Kuongorora kweCytogenetic kunoshandiswa kubatsira kuongorora cancer, kuronga kurapwa, kana kuona kuti kurapa kuri kushanda sei. Mimwe bvunzo, senge fluorescence in situ kusanganiswa (FISH), inogona zvakare kuitwa kutsvaga kumwe kuchinjika mumakromosomes.

Midline tract carcinoma inokura uye inopararira nekukurumidza.

Midline turakiti kenza neNUT geni shanduko kenza ine hukasha isingarapike.

Matanho eUdiki Midline Tract Carcinoma

Maitiro anoshandiswa kutsvaga kana gomarara rapararira kubva kwarakatanga kuenda kunzvimbo dziri padyo kana kune dzimwe nhengo dzemuviri inonzi staging. Iko hakuna yakajairwa system yekumisikidza hudiki midline turakiti carcinoma. Mhedzisiro yemiyedzo uye maitiro anoitwa kuongorora midline turakiti carcinoma anoshandiswa kubatsira kuita sarudzo nezve kurapwa.

Udiki midline turakiti carcinoma inogona kupararira kune iyo lymph node, iyo tambo yakakomberedza mapapu, pfupa remongo, kana pfupa.

Kurapa Sarudzo Kuongorora

PFUNGWA DZINOKOSHA

• Kune akasiyana marudzi ekurapa kwevana vane midline turakiti carcinoma.

• Vana vane midline tract carcinoma vanofanirwa kurapwa kwavo kuchirongwa nechikwata chevanachiremba vanova nyanzvi pakurapa gomarara rehucheche.

• Mhando nhatu dzekurapa dzinoshandiswa:

• Kuvhiya

• Radiation kurapa

• Chemotherapy

• Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

• Targeted kurapwa

• Kurapa kwehucheche midline turakiti carcinoma kunogona kukonzera mhedzisiro.

• Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

• Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kenza kurapwa.

• Yekutevera-bvunzo inogona kudikanwa.

Kune akasiyana marudzi ekurapa kwevana vane midline turakiti carcinoma.

Mamwe marapirwo akajairwa (iko kurapwa kwazvino kwashandiswa), uye kumwe kuedzwa mumakiriniki ekuedzwa A kurapwa kiriniki kuyedzwa chidzidzo chekutsvaga chakaitirwa kubatsira kuvandudza marapirwo azvino kana kuwana ruzivo marapirwo matsva evarwere vane gomarara. Kana kiriniki miedzo ikaratidza kuti kurapwa kutsva kuri nani pane kwese kurapwa, kurapwa kutsva kunogona kuve kwakajairwa kurapwa.

Nekuti kenza muvana isingawanzo, kutora chikamu mukutongwa kwekiriniki kunofanirwa kutariswa. Mimwe miedzo yekiriniki yakavhurwa chete kune varwere vasina kutanga kurapwa.

Vana vane midline tract carcinoma vanofanirwa kurapwa kwavo kuchirongwa nechikwata chevanachiremba vanova nyanzvi pakurapa gomarara rehucheche.

Kurapa kunozoonekwa nachiremba wevana oncologist, chiremba ane hunyanzvi hwekurapa vana vane gomarara. Vanachiremba oncologist vanoshanda nevamwe vana vezvehutano vana vanove nyanzvi dzekurapa vana vane gomarara uye vane hunyanzvi mune dzimwe nzvimbo dzemishonga. Izvi zvinogona kusanganisira vanachiremba vanotevera nevamwe:

• Chiremba wevana.

• Chiremba wechiremba wechiremba.

• Radiation oncologist.

• Nyanzvi yezvirwere.

• Mukoti wechiremba nyanzvi.

• Wezvemagariro.

• Rehabilitation nyanzvi.

• Nyanzvi yezvepfungwa.

• Mwana-hupenyu nyanzvi.

Mhando nhatu dzekurapa dzinoshandiswa:

Kuvhiya

Kuvhiya kubvisa bundu iri ndeimwe yekurapa kukuru kunoshandiswa kwevechidiki midline turakiti carcinoma.

Radiation kurapa

Radiation kurapa kurapwa kenza iyo inoshandisa yakakwira-simba x-rays kana mamwe marudzi e radiation kuuraya cancer maseru kana kuachengeta iwo kuti asakure. External radiation therapy inoshandisa muchina uri kunze kwemuviri kutumira radiation kune kenza.

Chemotherapy

Chemotherapy mushonga wekenza unoshandisa mishonga kumisa kukura kwemasero ekenza, kungave nekuuraya maseru kana nekuamisa iwo kubva pakupatsanuka. Kana chemotherapy ikatorwa nemuromo kana kujowa mutsinga kana mhasuru, mishonga inopinda muropa uye inogona kusvika masero emukenza mumuviri wese (systemic chemotherapy).

Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

Ichi chidimbu chikamu chinotsanangura kurapwa kuri kuongororwa mumakiriniki ekuedzwa. Zvinogona kusataura nezveese marapirwo matsva ari kuongororwa. Ruzivo nezve kiriniki miedzo inowanikwa kubva kuNCI webhusaiti.

Targeted kurapwa

Targeted Therapise kurapwa kunoshandisa zvinodhaka kana zvimwe zvinhu kuti zvione uye nekurwisa chaiwo maseru egomarara uku zvichikonzera kukuvara kushoma kumasero akajairwa. Nyowani yakanangwa kurapa zvinodhaka izvo zvinomisa cancer maseru kubva kukura zviri kuongororwa kuti zvirape midline turakiti carcinoma.

Kurapa kwehucheche midline turakiti carcinoma kunogona kukonzera mhedzisiro.

Kuti uwane ruzivo nezve mhedzisiro inotanga panguva yekurapa kenza, ona yedu Side Mhedzisiro peji.

Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

Kune vamwe varwere, kutora chikamu mumuedzo wekiriniki inogona kunge iri sarudzo yekurapa yakanyanya kunaka. Kliniki miedzo chikamu chekenza tsvagiridzo. Zvemakiriniki miedzo inoitwa kuti uone kana marapirwo matsva egomarara akachengeteka uye achishanda kana zvirinani pane akajairwa kurapwa.

Mazhinji emazuva ano marapirwo akajairwa ekenza akavakirwa pamavambo emakiriniki ekuedzwa. Varwere vanotora chikamu mukuyedzwa kwekiriniki vanogona kuwana kurapwa kwakaringana kana kuve pakati pevekutanga kurapwa kutsva.

Varwere vanotora chikamu mumiedzo yekiriniki zvakare vanobatsira kugadzirisa marapirwo achaitwa kenza mune ramangwana. Kunyangwe kana miedzo yemakiriniki isinga tangire kumarapirwo matsva anoshanda, anowanzo pindura mibvunzo yakakosha uye anobatsira kufambisira mberi kutsvagurudza.

Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kenza kurapwa.

Mimwe miedzo yekiriniki inosanganisira chete varwere vasati vagamuchira kurapwa. Mimwe miedzo yekuedza kurapwa kwevarwere vane kenza haina kuve nani. Kune mamwezve emakiriniki miedzo inoedza nzira nyowani dzekumisa cancer kubva kudzokororazve (kudzoka) kana kudzikisira mhedzisiro yemakenza kurapwa.

Kuedzwa kwemakiriniki kuri kuitika munzvimbo zhinji dzenyika. Ruzivo nezve kiriniki miedzo inotsigirwa neNCI inogona kuwanikwa paNCI yekiriniki miedzo yekutsvaga peji rewebhu. Kliniki miedzo inotsigirwa nemamwe masangano inogona kuwanikwa pane yeClinicalTrials.gov webhusaiti.

Yekutevera-bvunzo inogona kudikanwa.

Mimwe miedzo yakaitwa kuongorora gomarara kana kutsvaga danho rekenza inogona kudzokororwa. Dzimwe bvunzo dzinodzokororwa kuitira kuti vaone kuti kurapa kuri kushanda sei. Sarudzo nezvekuti uenderere mberi, shandura, kana kumisa kurapwa kunogona kunge kuchibva pamhedzisiro yeiyi bvunzo.

Mimwe bvunzo ichaenderera ichiitwa nguva nenguva mushure mekunge kurapwa kwapera. Mhedzisiro yeiyi bvunzo inogona kuratidza kana mamiriro emwana wako achinja kana kana gomarara radzoka (dzoka). Iyi bvunzo dzimwe nguva inonzi yekuteedzera-bvunzo kana kuongorora-kumusoro.

Kurapa kweVachangobva Kuzivikanwa Vechidiki Midline Tract Carcinoma

Kuti uwane ruzivo nezve marapirwo akanyorwa pazasi, ona iyo Chikamu Sarudzo Yekutarisa Chikamu.

Iko hakuna kwakajairika kurapwa kweachangobva kuongororwa midline turakiti kenza neNUT geni shanduko. Kurapa kunogona kusanganisira zvinotevera:

• Kuvhiya kubvisa bundu.

• External radiation kurapwa.

• Chemotherapy.

• Kuongororwa kwekiriniki kweiyo nyowani yakanangwa yekurapa mushonga.

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Kurapa kweRecrerent Childhood Midline Tract Carcinoma

Kuti uwane ruzivo nezve marapirwo akanyorwa pazasi, ona iyo Chikamu Sarudzo Yekutarisa Chikamu.

Kurapa kwekenza yepakati yepakati yepakati kenza neNUT geni shanduko inogona kusanganisira zvinotevera:

• Kuongororwa kwekiriniki kunoongorora muyenzaniso wemota yemurwere kune mamwe magene ekuchinja. Rudzi rwekurapa kwakanangwa kuchapihwa kumurwere kunoenderana nerudzi rwechinjo yemajini.

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Kuti Udzidze Zvakawanda Pamusoro Pehucheche Midline Tract Carcinoma

Kuti uwane rumwe ruzivo kubva kuNational Cancer Institute nezve midline tract carcinoma, ona zvinotevera:

• Musoro uye Neck Cancer Kumba Peji

• Computed Tomography (CT) Scans uye Cancer

Kuti uwane rumwe ruzivo rwegomarara rehucheche uye zvimwe zvecancer zviwanikwa, ona zvinotevera:

• Nezve Kenza

• Cancers Yevacheche

• Kurapa Kutsvaga Kwevana Cancer Buda Disclaimer

• Mahedhi Ekupedzisira Ekurapwa kweKenza Yevacheche

• Vechidiki uye Vechidiki Vakuru vane Cancer

• Vana vane Cancer: Nhungamiro Yevabereki

• Kenza muVana neVachiri kuyaruka

• Stage

• Kurarama neCancer

• Mibvunzo Yekubvunza Wako Chiremba nezveCancer

• Kune Vakapona uye Vanotarisira

Nezve Iyi Pfupiso

Nezve

Chiremba Dhata Query () ndeye National Cancer Institute's (NCI's) yakazara kenza ruzivo ruzivo. Dhatabhesi ye ine pfupiso yeruzivo rwechizvino-zvino pamusoro pekudzivirira gomarara, kuona, genetics, kurapwa, kuchengetedzwa kwekutsigira, uye mushonga unowirirana uye unotsiva. Mazhinji pfupiso anouya mushanduro mbiri. Iwo ehutano nyanzvi shanduro dzine ruzivo rwakadzama rwakanyorwa muhunyanzvi mutauro. Shanduro dzevarwere dzakanyorwa zviri nyore kunzwisisa, mutauro usingashandise hunyanzvi. MaBhaibheri ese ari maviri ane ruzivo rwegomarara rwakarurama uye rwuri parizvino uye shanduro zhinji dzinowanikwa muchiSpanish.

ibasa reNCI. Iyo NCI chikamu cheNational Institutes of Health (NIH). NIH inzvimbo yehurumende yemubatanidzwa yekutsvagisa biomedical. Idzo pfupiso dze dzinovakirwa pakazvimiririra ongororo yezvinyorwa zvekurapa. Haasi iwo marongero emutemo eNCI kana iyo NIH.

Chinangwa cheichi Chidimbu

Iyi pfupiso yeruzivo rwegomarara rwe ine ruzivo rwezvino nezve kurapwa kwehudiki midline turakiti carcinoma. Izvo zvakagadzirirwa kuzivisa uye kubatsira varwere, mhuri, uye vanochengeta. Izvo hazvipe zvakarongeka nhungamiro kana kurudziro yekuita sarudzo nezve hutano hutano.

Vaongorori uye maDudziro

Edhisheni Mabhodhi anonyora iyo kenza ruzivo rwekupfupisa uye nekuzvichengeta zviri zvechizvino-zvino. Aya maBhodi akaumbwa nenyanzvi mukurapa gomarara uyehumwe hunyanzvi hune hukama negomarara. Idzo pfupiso dzinoongororwa kazhinji uye shanduko dzinoitwa kana paine ruzivo rutsva. Zuva pane pfupiso yega yega ("Yakagadziridzwa") izuva rekuchinja kwazvino.

Ruzivo rwuri muchidimbu chevarwere rwakatorwa kubva kuhutano nyanzvi vhezheni, iyo inoongororwa nguva zhinji uye kuvandudzwa sezvinodiwa, ne Pediatric Treatment Edhiyo Board.

Clinical Kuedzwa Ruzivo

Kuongororwa kwekiriniki kudzidza kupindura mubvunzo wesainzi, sekunge kurapwa kumwe kuri nani pane kumwe. Miedzo yakavakirwa pazvidzidzo zvakapfuura uye izvo zvakadzidzwa murabhoritari. Muedzo wega wega unopindura mimwe mibvunzo yesainzi kuitira kuti uwane nzira nyowani uye dziri nani dzekubatsira varwere vegomarara. Munguva yekurapwa kwekuedzwa kwemakiriniki, ruzivo runotorwa pamusoro pemhedzisiro yekurapa kutsva uye nemabatiro arinoita. Kana kiriniki yekuyedzwa ikaratidza kuti kurapwa kutsva kuri nani pane imwe irikushandiswa parizvino, kurapwa kutsva kunogona "kujairika" Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki. Mimwe miedzo yekiriniki yakavhurwa chete kune varwere vasina kutanga kurapwa.

Zvirwere zvemakiriniki zvinogona kuwanikwa pamhepo pawebhusaiti yeNCI. Kuti uwane rumwe ruzivo, fonera Cancer Information Service (CIS), nzvimbo yekudyidzana yeNCI, pa1-800-4-CANCER (1-800-422-6237).

Mvumo yekushandisa Ichi Chidimbu

chiratidzo chakanyoreswa. Zvinyorwa zvemagwaro ePDP zvinogona kushandiswa zvakasununguka semavara. Iyo haigone kuzivikanwa seNCI kenza yeruzivo pfupiso kunze kwekunge iyo pfupiso yose yaratidzwa uye ichigadziriswa nguva dzose. Zvisinei, mushandisi anobvumidzwa kunyora chirevo chakadai se "NCI's cancer information muchidimbu nezvekudzivirira gomarara repazamu inotaura njodzi nenzira inotevera:

Nzira yakanakisa yekutsanangura iyi pfupiso ye ndeiyi:

Mifananidzo iri muchidimbu ino inoshandiswa nemvumo yemunyori (s), muimbi, uye / kana muparidzi kuti ishandiswe mupfupiso dze chete. Kana iwe uchida kushandisa chifananidzo kubva muchidimbu che uye usiri kushandisa pfupiso yese, unofanirwa kuwana mvumo kubva kumuridzi. Iyo haigone kupihwa neNational Cancer Institute. Ruzivo nezve kushandisa iyo mifananidzo muchidimbu ichi, pamwe nemamwe akawanda mifananidzo ine chekuita nekenza inogona kuwanikwa muZviratidzo Pamhepo. Zvinoonekwa paInternet muunganidzwa wemifananidzo inopfuura 3,000 yesainzi.

Disiki

Ruzivo ruri muzvipfupiso urwu harufanire kushandiswa kuita sarudzo pamusoro pekubhadhara inishuwarenzi. Rumwe ruzivo nezve kufukidzwa kweinishuwarenzi kunowanikwa paCancer.gov pane iyo Managing Cancer Care peji.

Taura nesu

Ruzivo rwakawanda nezve kutibata nesu kana kugamuchira rubatsiro neCancer.gov webhusaiti inogona kuwanikwa pane Yedu Kubata Nedu Rubatsiro peji. Mibvunzo inogona zvakare kuendeswa kuCancer.gov kuburikidza neiyo webhusaiti E-mail Isu.

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