Mhando / lymphoma / murwere / primary-cns-lymphoma-kurapwa-pdq

Yekutanga CNS Lymphoma Kurapa (®) -Patient Shanduro

General Ruzivo nezvePuraimari CNS Lymphoma

PFUNGWA DZINOKOSHA

• Primary central nervous system (CNS) lymphoma chirwere umo maronda (gomarara) maseru anoumba mukati mehombodo yeuropi uye / kana musana.

• Kuva nehutachiona husina simba hunogona kuwedzera njodzi yekuvandudza yekutanga CNS lymphoma.

• Kuyedza kunoongorora maziso, huropi, uye musana wemutsipa kunoshandiswa kuona (kuwana) uye kuongorora yekutanga CNS lymphoma.

• Zvimwe zvinhu zvinokanganisa kufungidzira (mukana wekupora) uye sarudzo dzekurapa.

Primary central nervous system (CNS) lymphoma chirwere umo maronda (gomarara) maseru anoumba mukati mehombodo yeuropi uye / kana musana.

Lymphoma chirwere icho chinotyisa (gomarara) maseru anoumba mune lymph system. Iyo lymph system chikamu chemuviri immune uye inoumbwa neiyo lymph, lymph midziyo, lymph node, spleen, thymus, tonsils, uye mwongo wemabhonzo. MaLymphocyte (anotakurwa mune iyo lymph) anofamba mukati uye kunze kwenzvimbo yepakati yetsinga (CNS). Inofungidzirwa kuti mamwe eaya maLymphocyte anova akaipa uye anokonzeresa kuti lymphoma igadzike muCNS. Chekutanga CNS lymphoma inogona kutanga muuropi, musana, kana meninges (iwo matara anoumba chifukidziro chekunze chehuropi). Nekuti iro ziso riri padhuze nehuropi, yekutanga CNS lymphoma inogona zvakare kutanga muziso (inonzi ocular lymphoma).

Anatomy yeiyo lymph system, inoratidza iyo lymph midziyo uye lymph nhengo dzinosanganisira lymph node, tonsils, thymus, spleen, uye mwongo wemapfupa. Lymph (clear fluid) uye maLymphocyte anofamba kuburikidza nemidziyo yema lymph uye mune ma lymph node uko ma lymphocyte anoparadza zvinokuvadza Iyo lymph inopinda muropa kuburikidza nemutsipa muhombe padyo nemoyo.

Kuva nehutachiona husina simba hunogona kuwedzera njodzi yekuvandudza yekutanga CNS lymphoma.

Chero chipi zvacho chinowedzera mukana wako wekutora chirwere chinonzi njodzi chinhu. Kuva nenjodzi hazvireve kuti uchawana gomarara; kusava nenjodzi hazvireve kuti hauzobatwe negomarara. Taura nachiremba wako kana iwe uchifunga kuti ungave uri panjodzi.

Chekutanga CNS lymphoma inogona kuitika kune varwere vakawana immunodeficiency syndrome (AIDS) kana zvimwe zvinetso zvemuviri wemuviri kana vakave neitsvo yekuisira. Kuti uwane rumwe ruzivo nezve lymphoma mune varwere vane AIDS, ona pfupiso ye pamusoro peAIDS-Inoenderana neLymphoma Treatment.

Kuyedza kunoongorora maziso, huropi, uye musana wemutsipa kunoshandiswa kuona (kuwana) uye kuongorora yekutanga CNS lymphoma.

Iyi inotevera bvunzo uye maitiro anogona kushandiswa:

• Kuongorora kwepanyama uye nhoroondo: Kuongororwa kwemuviri kutarisa zviratidzo zvehutano, kusanganisira kuongorora zviratidzo zvehosha, zvakadai semapundu kana chero chinhu chinoratidzika sechisina kujairika. Nhoroondo yemaitiro ehutano hwemurwere uye kurwara kwakapfuura uye kurapwa kuchatorwawo.

• Neurological bvunzo: akateedzana emibvunzo uye bvunzo kutarisa huropi, musana, uye tsinga basa. Bvunzo dzinoongorora chimiro chemunhu chepfungwa, kubatana, kugona kufamba zvakajairika, uye mashandiro, pfungwa, uye mafungiro zvinoshanda zvakadii. Izvi zvinogona zvakare kunzi bvunzo yeurouro kana bvunzo yetsinga.

• Slit-mwenje bvunzo bvunzo: bvunzo inoshandisa yakakosha maikorosikopu ine inopenya, yakatetepa yakatsemurwa yemwenje kutarisa kunze nekunze kweziso.

• MRI (magnetic resonance imaging): Maitiro anoshandisa magineti, masaisai eredhiyo, uye komputa kugadzira yakateedzana mifananidzo yakajeka yenzvimbo dziri mukati meuropi nemuzongoza. Chinhu chinonzi gadolinium chinojowa mumurwere kuburikidza netsinga. Iyo gadolinium inounganidza yakatenderedza maseru ekenza kuitira kuti varatidze kupenya mumufananidzo. Iyi nzira inonziwo nyukireya magnetic resonance imaging (NMRI).

• PET scan (positron emission tomography scan): Iyo nzira yekuwana yakaipa malonda maseru mumuviri. Chishoma che radioactive glucose (shuga) inoiswa mutsinga. Iyo PET scanner inotenderera yakatenderedza muviri uye inogadzira mufananidzo wepo glucose iri kushandiswa mumuviri. Malignant tumarara maseru anoratidza kupenya mumufananidzo nekuti anoshanda uye anotora glucose yakawanda kupfuura zvinoita maseru akajairwa.

• Lumbar puncture: Maitiro anoshandiswa kutora cerebrospinal fluid (CSF) kubva pamutsipa wepelinha. Izvi zvinoitwa nekuisa tsono pakati pemabhonzo maviri mumuzongoza nekupinda muCSF yakakomberedza musana uye kubvisa sampu yemvura. Muenzaniso we CSF unotariswa pasi pe microscope yezviratidzo zvemarara maseru. Muenzaniso unogona zvakare kutariswa kuwanda kweprotein uye glucose. Iyo yakakwira kupfuura yakajairwa huwandu hwepuroteni kana yakaderera pane yakajairwa huwandu hweshuga inogona kunge iri chiratidzo chebundu. Maitiro aya anonzi zvakare LP kana musana tap.

Lumbar kubaya. Murwere akarara panzvimbo yakamonana patafura. Mushure mekunge diki nzvimbo kumucheto kumashure yave chiveve, tsono yemusana (tsono refu, nhete) inoiswa muchikamu chezasi chepamuviri mbichana kubvisa cerebrospinal fluid (CSF, inoratidzwa mublue). Mvura yacho inogona kutumirwa kurabhoritari kunoongororwa.

• Stereotactic biopsy: Maitiro ebiopsy anoshandisa komputa uye 3-dimensional (3-D) scanning mudziyo kuwana nzvimbo yemarara uye kutungamira kubviswa kwetissue kuti igone kutariswa pasi pe microscope kutarisa zviratidzo zvecancer.

Iyi miedzo inotevera inogona kuitwa pane sampuli yetishu inobviswa.

• Kuyerera cytometry: Kuongororwa kwerabhoritari kunoyera huwandu hwamasero mune imwe sampuro, muzana yemasero ehupenyu mune imwe sampuro, uye mamwe maitiro emaseru, senge saizi, chimiro, uye kuvepo kwethumba (kana zvimwe) mamaki pane sero pamusoro. Masero kubva pamuenzaniso weropa remurwere, mwongo wemapfupa, kana zvimwe zvinyama zvakasvibiswa nedhayi re fluorescent, rakaiswa mune mvura, uye ndokuzopfuura rimwe panguva kuburikidza nemwenje wechiedza. Mhedzisiro yekubvunzurudza inoenderana nekuti maseru aive akasvibiswa neiyo fluorescent dhayi anoita sei padanda rechiedza. Uyu muedzo unoshandiswa kubatsira kuongorora uye kubata mamwe marudzi ekenza, senge leukemia uye lymphoma.

• Immunohistochemistry: Kuongororwa kwerabhoritari inoshandisa masoja ekudzivirira mamwe maantigen (mamaki) mune imwe sampuro yetishu yemurwere. Masoja ekudzivirira chirwere anowanzo sunganidzwa ne enzyme kana dhayi ye fluorescent. Mushure mekunge maantibodies akasunga kune yakasarudzika antigen mune yeiyo sampuli, iyo enzyme kana dhayi inoitwa, uye iyo antigen inogona kuzoonekwa pasi pe microscope. Rudzi urwu rweyedzo runoshandiswa kubatsira kuongorora gomarara uye kubatsira kutaurira imwe mhando yekenza kubva kune imwe mhando yegomarara.

• Kuongorora kweCytogenetic: Kuongororwa kwerabhoritari umo ma chromosomes emaseru mune muyenzaniso weropa kana mongo wemapfupa anoverengwa uye kuongororwa chero shanduko, sekutyorwa, kushaikwa, kurongedzwa patsva, kana mamwe ma chromosomes. Shanduko mune mamwe ma chromosomes inogona kunge iri chiratidzo checancer. Kuongorora kweCytogenetic kunoshandiswa kubatsira kuongorora cancer, kuronga kurapwa, kana kuona kuti kurapa kuri kushanda sei.

• FISH (fluorescence in situ hybridization): Kuedzwa kwerabhoritari kunoshandiswa kutarisa uye kuverenga majeni kana ma chromosomes mumasero nematukisi. Zvidimbu zveDNA zvine dhayi ye fluorescent zvinogadzirwa murabhoritari uye zvinowedzerwa kune imwe sampuli yemasero emurwere kana zvinyama. Kana zvidimbu izvi zvakavezwa zveDNA zvonamatira kune mamwe mageneti kana nzvimbo dzekromosomes mumuenzaniso, dzinovhenekera kana dzatariswa pasi pefluorescent microscope. Chiyero cheFISH chinoshandiswa kubatsira kuongorora kenza uye kubatsira kuronga kurapwa.

• Yakazara huwandu hweropa (CBC) nemusiyano: Maitiro umo muyenzaniso weropa unodhonzwa nekuongororwa zvinotevera:

• Huwandu hwemasero matsvuku eropa nemaplatelet.

• Nhamba uye mhando yemasero machena eropa.

• Huwandu hwehemoglobin (protein inotakura oxygen) mumasero matsvuku eropa.

• Chikamu chemuenzaniso weropa chakaumbwa nemasero matsvuku eropa.

Yakazara kuverenga ropa (CBC). Ropa rinounganidzwa nekupinza tsono mutsinga uye richiita kuti ropa riyerere muhubhu. Muenzaniso weropa unotumirwa murabhoritari uye masero matsvuku eropa, masero machena eropa, uye maplatelet anoverengwa. Iyo CBC inoshandiswa kuyedza, kuongorora, uye kuongorora akawanda mamiriro akasiyana.

• Ropa kemesitiri zvidzidzo: Maitiro umo muyedzo weropa unoongororwa kuyera huwandu hwezvimwe zvinhu zvakaburitswa muropa nenhengo uye nyama munyama. Chinhu chisina kujairika (chakakwirira kana chakaderera pane zvakajairwa) chiyero chechinhu chinogona kunge chiri chiratidzo chechirwere.

Zvimwe zvinhu zvinokanganisa kufungidzira (mukana wekupora) uye sarudzo dzekurapa.

Kufungidzira (mukana wekupora) kunoenderana nezvinotevera:

• Zera remurwere uye hutano hwese.

• Iwo mwero wezvimwe zvinhu muropa uye cerebrospinal fluid (CSF).

• Iko iko bundu riri mukati memukati memagetsi system, ziso, kana zvese zviri zviviri.

• Kuti murwere ane AIDS.

Sarudzo dzekurapa dzinoenderana nezvinotevera:

• Chikamu checancer.

• Iko iko bundu riri munharaunda yepakati yetsinga.

• Zera remurwere uye hutano hwese.

• Kunyangwe kenza ichangobva kuongororwa kana kuti yadzokazve (dzoka).

Kurapa kwekutanga CNS lymphoma inoshanda zvakanyanya kana bundu risina kupararira kunze kwecrebrum (chikamu chikuru cheuropi) uye murwere ari pasi pemakore makumi matanhatu, achikwanisa kuita zviitiko zvezuva nezuva, uye haana AIDS kana zvimwe zvirwere izvo kushayisa simba immune system.

Kujekesa Primary CNS Lymphoma

PFUNGWA DZINOKOSHA

• Mushure mekutanga central central system (CNS) lymphoma yaonekwa, kuyedzwa kunoitwa kuti uone kana kenza maseru akapararira mukati mehuropi uye musana kana kune zvimwe zvikamu zvemuviri.

• Pane nzira nhatu dzinopararira negomarara mumuviri.

• Gomarara rinogona kutapukira kubva kwarakatanga kuenda kune dzimwe nhengo dzemuviri.

• Iko hakuna yakajairwa sisitimu sisitimu yekutanga CNS lymphoma.

Mushure mekutanga central central system (CNS) lymphoma yaonekwa, kuyedzwa kunoitwa kuti uone kana kenza maseru akapararira mukati mehuropi uye musana kana kune zvimwe zvikamu zvemuviri.

Kana yekutanga CNS lymphoma ichiramba ichikura, kazhinji haina kupararira kupfuura yepakati sisitimu kana ziso. Maitiro anoshandiswa kutsvaga kana gomarara rapararira anonzi staging. Izvo zvakakosha kuti uzive kana gomarara rapararira kune dzimwe nhengo dzemuviri kuitira kuronga kurapwa. Iyi inotevera bvunzo uye maitiro anogona kushandiswa mune yekuratidzira maitiro:

• CT scan (CAT scan): Maitiro anoita akateedzana emifananidzo yakajeka yenzvimbo dziri mukati memuviri, inotorwa kubva kumakona akasiyana. Mifananidzo yacho inogadzirwa nekombuta yakabatana neiyo x-ray muchina. Dhayi inogona kuiswa jekiseni kana kumedzwa kubatsira nhengo kana zvinyama kuratidza zvakajeka. Iyi nzira inonziwo computed tomography, computerized tomography, kana komputa axial tomography. Yekutanga CNS lymphoma, CT scan inoitwa yechipfuva, dumbu, uye pelvis (chikamu chemuviri pakati pehudyu).

• PET scan (positron emission tomography scan): Iyo nzira yekuwana yakaipa malonda maseru mumuviri. Chishoma che radioactive glucose (shuga) inoiswa mutsinga. Iyo PET scanner inotenderera yakatenderedza muviri uye inogadzira mufananidzo wepo glucose iri kushandiswa mumuviri. Malignant tumarara maseru anoratidza kupenya mumufananidzo nekuti anoshanda uye anotora glucose yakawanda kupfuura zvinoita maseru akajairwa. PET scan uye CT scan inogona kuitwa panguva imwe chete. Iyi inonzi PET-CT.

• MRI (magnetic resonance imaging): Maitiro anoshandisa magineti, masaisai eredhiyo, uye komputa kugadzira yakateedzana mifananidzo yakajeka yenzvimbo dziri mukati memuviri. Iyi nzira inonziwo nyukireya magnetic resonance imaging (NMRI).

• Bone marrow aspiration uye biopsy: Kubviswa kwemongo wefupa, ropa, uye chidimbu chefupa nekuisa tsono isina mhango muhudyu kana pfupa rechipfuva. Nyanzvi yezvirwere anoona pfupa, ropa, uye pfupa pasi pe microscope kutsvaga zviratidzo zvegomarara.

Bone marora chishuwo uye biopsy. Mushure mekunge nzvimbo diki yeganda yave nechiveve, tsono yemongo wemapfupa inoiswa mupfupa rehudyu remurwere. Samples reropa, bhonzo, uye mwongo wemapfupa zvinobviswa kuti zviongororwe pasi pe microscope.

Pane nzira nhatu dzinopararira negomarara mumuviri.

Kenza inogona kupararira kuburikidza nematinji, iyo lymph system, uye neropa:

• Tishu. Kenza inopararira kubva kwayakatanga nekukura ichipinda munzvimbo dziri pedyo.

• Lymph maitiro. Kenza inopararira kubva kwayakatanga nekupinda muiyo lymph system. Kenza inofamba nemumidziyo yema lymph ichienda kune dzimwe nhengo dzemuviri.

• Ropa. Kenza inopararira kubva payakatanga nekupinda muropa. Kenza inofamba nemidzi yeropa ichienda kune dzimwe nhengo dzemuviri.

Gomarara rinogona kutapukira kubva kwarakatanga kuenda kune dzimwe nhengo dzemuviri.

Kana kenza ikapararira kune chimwe chikamu chemuviri, inonzi metastasis. Cancer maseru anotsemuka kubva kwaakatanga (iro bundu rekutanga) uye achifamba kuburikidza neye lymph system kana ropa.

• Lymph maitiro. Gomarara rinopinda mu "lymph system", rinofamba nemumidziyo ye "lymph", uye rinogadzira bundu (metastatic tumor) mune chimwe chikamu chemuviri.

• Ropa. Kenza inopinda muropa, inofamba nemutsinga dzeropa, yoita bundu (metastatic tumor) mune chimwe chikamu chemuviri.

Iyo metastatic bundu irwo rudzi rwecancer seyakanyanya bundu. Semuenzaniso, kana chikuru CNS lymphoma ichipararira kuchiropa, masero emukenza ari muchiropa ari maseru lymphoma. Hosha ndeye metastatic CNS lymphoma, kwete kenza yechiropa.

Iko hakuna yakajairwa sisitimu sisitimu yekutanga CNS lymphoma.

Dzokororo Primary CNS Lymphoma

Recurrent primary central nervous system (CNS) lymphoma igomarara rakadzokazve (kudzoka) mushure mekurapwa. Chekutanga CNS lymphoma inowanzo dzokera muuropi kana muziso.

Kurapa Sarudzo Kuongorora

PFUNGWA DZINOKOSHA

• Kune akasiyana marudzi ekurapa kwevarwere vane yekutanga CNS lymphoma.

• Matatu matatu ekurapa anoshandiswa:

• Radiation kurapa

• Chemotherapy

• Steroid kurapa

• Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

• Yakakwira-dose chemotherapy ine stem cell yekuisa

• Targeted kurapwa

• Kurapa kwepakutanga CNS lymphoma kunogona kukonzera mhedzisiro.

• Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

• Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kenza kurapwa.

• Yekutevera-bvunzo inogona kudikanwa.

Kune akasiyana marudzi ekurapa kwevarwere vane yekutanga CNS lymphoma.

Mhando dzakasiyana dzekurapa dzinowanikwa kuvarwere vane primary central nervous system (CNS) lymphoma. Mamwe marapirwo akajairwa (iko kurapwa kwazvino kwashandiswa), uye kumwe kuedzwa mumakiriniki ekuedzwa A kurapwa kiriniki kuyedzwa chidzidzo chekutsvaga chakaitirwa kubatsira kuvandudza marapirwo azvino kana kuwana ruzivo marapirwo matsva evarwere vane gomarara. Kana kiriniki miedzo ikaratidza kuti kurapwa kutsva kuri nani pane kwese kurapwa, kurapwa kutsva kunogona kuve kwakajairwa kurapwa. Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki. Mimwe miedzo yekiriniki yakavhurwa chete kune varwere vasina kutanga kurapwa.

Kuvhiya hakushandiswe kurapa yekutanga CNS lymphoma.

Matatu matatu ekurapa anoshandiswa:

Radiation kurapa

Radiation kurapa kurapwa kenza iyo inoshandisa yakakwira-simba x-rays kana mamwe marudzi e radiation kuuraya cancer maseru kana kuachengeta iwo kuti asakure. Kune mhando mbiri dze radiation radiation:

• External radiation therapy inoshandisa muchina uri kunze kwemuviri kutumira radiation kune kenza. Nekuti yekutanga CNS lymphoma inopararira mukati mehuropi, ekunze radiation kurapwa kunopihwa kune hwese brain Izvi zvinodaidzwa kuti huropi hwehutachiona hwehutachiona.

• Yemukati radiation kurapwa kunoshandisa radioactive chinhu chakavharirwa mune tsono, mhodzi, waya, kana makateti anoiswa akananga mukati kana padyo nekenza.

Maitiro ekurapwa nemwaranzi anoenderana nekuti murwere ane primary CNS lymphoma neAIDS. External radiation therapy inoshandiswa kurapa yekutanga CNS lymphoma.

Yepamusoro-dhiza radiation kurapwa kuuropi kunogona kukuvadza hutano hutano uye kukonzera kusagadzikana kunogona kukanganisa kufunga, kudzidza, kugadzirisa matambudziko, kutaura, kuverenga, kunyora, uye ndangariro. Zvemakiriniki miedzo yakaedza kushandiswa kwechemotherapy moga kana pamberi peiyo radiation kurapwa kudzikisira kukanganisa kwehutano hutano huturu hunoitika nekushandisa radiation radiation.

Chemotherapy

Chemotherapy mushonga wekenza unoshandisa mishonga kumisa kukura kwemasero ekenza, kungave nekuuraya maseru kana nekuamisa iwo kubva pakupatsanuka. Kana chemotherapy ikatorwa nemuromo kana kujowa mutsinga kana mhasuru, mishonga inopinda muropa uye inogona kusvika masero emukenza mumuviri wese (systemic chemotherapy). Kana chemotherapy ikaiswa yakanangana necerebrospinal fluid (intrathecal chemotherapy), nhengo, kana dumbu remuviri senge dumbu, mishonga inonyanya kukanganisa maseru ekenza munzvimbo idzodzo (chemotherapy yedunhu).

Nzira iyo chemotherapy inopihwa inoenderana nekuti bundu riripi muCNS kana ziso. Chekutanga CNS lymphoma inogona kurapwa ne systemic chemotherapy, intrathecal chemotherapy uye / kana intraventricular chemotherapy, mune iyo anticancer zvinodhaka zvinoiswa mukati memhepo (yakazara-yakazara mvura) yeuropi. Kana yekutanga CNS lymphoma inowanikwa muziso, anticancer zvinodhaka zvinojowa zvakananga mu vitreous humor (jelly-kunge chinhu) mukati meziso.

Intrathecal chemotherapy. Anticancer zvinodhaka zvinopinda mukati meiyo intrathecal nzvimbo, inova iyo nzvimbo inobata iyo cerebrospinal fluid (CSF, inoratidzwa mublue). Pane nzira mbiri dzakasiyana dzekuita izvi. Imwe nzira, inoratidzwa muchikamu chepamusoro chemufananidzo, kuisa majekiseni mumugodhi weOmaya (mudziyo wakaita sedome wakaiswa pasi peganda panguva yekuvhiyiwa; inobata mishonga painenge ichiyerera nepombi diki ichienda muuropi ). Imwe nzira, inoratidzwa muchikamu chepazasi chemufananidzo, kupinza mishonga yakananga muCSF muchikamu chezasi chepamuviri, mushure mekunge nharaunda diki kumusana wezasi yave nechiveve.

Netiweki yetsinga dzeropa uye munyama, inonzi iropa-yechipingaidzo, inodzivirira uropi kubva kuzvinhu zvinokuvadza. Ichi chipingaidzo chinogona zvakare kuchengetedza anticancer mishonga kuti isvike kuuropi. Kuti ubate CNS lymphoma, mamwe madhiragi anogona kushandiswa kuvhura pakati pemasero muropa-rehuropi chipingaidzo. Izvi zvinonzi ropa-uropi chipingaidzo kukanganiswa. Anticancer zvinodhaka zvinopinda muropa zvinogona kusvika kuuropi.

Steroid kurapa

Steroid mahormone akagadzirwa zvakasikwa mumuviri. Izvo zvinogona zvakare kugadzirwa murabhoritari uye kushandiswa semishonga. Glucocorticoids ndeye steroid zvinodhaka zvine anticancer maitiro mune lymphomas.

Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

Ichi chidimbu chikamu chinotsanangura kurapwa kuri kuongororwa mumakiriniki ekuedzwa. Zvinogona kusataura nezveese marapirwo matsva ari kuongororwa. Ruzivo nezve kiriniki miedzo inowanikwa kubva kuNCI webhusaiti.

Yakakwira-dose chemotherapy ine stem cell yekuisa

Yakakwira madosi ekemotherapy anopiwa kuuraya cancer maseru. Masero ane hutano, kusanganisira masero anogadzira ropa, anoparadzwa nekenza kurapwa. Stem cell transplant kurapwa kwekutsiva maseru anogadzira ropa. Masero emashizha (masero eropa asina kusimba) anobviswa muropa kana mwongo wemapfupa emurwere kana mupi uye anoomeswa nechando. Mushure mekunge murwere apedza chemotherapy, maseru akachengetwa anonyungudutswa uye ndokudzoserwa kumurwere kuburikidza nekumukiswa. Aya akadzikiswa maseru emadzinde anokura kuita (uye kudzoreredza) masero eropa emuviri.

Targeted kurapwa

Targeted therapy mhando yekurapa inoshandisa zvinodhaka kana zvimwe zvinhu kurwisa cancer maseru. Kurapa kwakanangwa kunowanzo kukonzera kukuvara kushoma kune masero akajairwa pane chemotherapy kana radiation radiation inoita Monoclonal antibody therapy ndeimwe yemhando yekurapa kwakanangidzirwa kuri kudzidziswa mukurapa kwekutanga CNS lymphoma.

Monoclonal antibody therapy ndeye kenza kurapa iyo inoshandisa antibodies inogadzirwa murabhoritari kubva kune imwechete mhando ye immune immune cell. Aya ma antibodies anokwanisa kuona zvinhu pane cancer cancer kana zvakajairika zvinhu zvinogona kubatsira gomarara maseru kukura. Masoja ekudzivirira chirwere anonamira pazvinhu uye anouraya maseru egomarara, anovharira kukura kwawo, kana kuti aachengetedze kubva pakupararira. Monoclonal antibodies inopihwa nekumisirwa. Inogona kushandiswa yoga kana kutakura zvinodhaka, chepfu, kana zvinhu zvine radioactive zvakanangana nemasero ekenza. Rituximab rudzi rwe monoclonal antibody inoshandiswa kurapa ichangobva kuongororwa yekutanga CNS lymphoma mune varwere vasina AIDS.

Kurapa kwepakutanga CNS lymphoma kunogona kukonzera mhedzisiro.

Kuti uwane ruzivo nezve mhedzisiro inokonzerwa nekurapwa kwegomarara, ona yedu Side Mhedzisiro peji.

Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

Kune vamwe varwere, kutora chikamu mumuedzo wekiriniki inogona kunge iri sarudzo yekurapa yakanyanya kunaka. Kliniki miedzo chikamu chekenza tsvagiridzo. Zvemakiriniki miedzo inoitwa kuti uone kana marapirwo matsva egomarara akachengeteka uye achishanda kana zvirinani pane akajairwa kurapwa.

Mazhinji emazuva ano marapirwo akajairwa ekenza akavakirwa pamavambo emakiriniki ekuedzwa. Varwere vanotora chikamu mukuyedzwa kwekiriniki vanogona kuwana kurapwa kwakaringana kana kuve pakati pevekutanga kurapwa kutsva.

Varwere vanotora chikamu mumiedzo yekiriniki zvakare vanobatsira kugadzirisa marapirwo achaitwa kenza mune ramangwana. Kunyangwe kana miedzo yemakiriniki isinga tangire kumarapirwo matsva anoshanda, anowanzo pindura mibvunzo yakakosha uye anobatsira kufambisira mberi kutsvagurudza.

Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kenza kurapwa.

Mimwe miedzo yekiriniki inosanganisira chete varwere vasati vagamuchira kurapwa. Mimwe miedzo yekuedza kurapwa kwevarwere vane kenza haina kuve nani. Kune mamwezve emakiriniki miedzo inoedza nzira nyowani dzekumisa cancer kubva kudzokororazve (kudzoka) kana kudzikisira mhedzisiro yemakenza kurapwa.

Kuedzwa kwemakiriniki kuri kuitika munzvimbo zhinji dzenyika. Ruzivo nezve kiriniki miedzo inotsigirwa neNCI inogona kuwanikwa paNCI yekiriniki miedzo yekutsvaga peji rewebhu. Kliniki miedzo inotsigirwa nemamwe masangano inogona kuwanikwa pane yeClinicalTrials.gov webhusaiti.

Yekutevera-bvunzo inogona kudikanwa.

Mimwe miedzo yakaitwa kuongorora gomarara kana kutsvaga danho rekenza inogona kudzokororwa. Dzimwe bvunzo dzinodzokororwa kuitira kuti vaone kuti kurapa kuri kushanda sei. Sarudzo nezvekuti uenderere mberi, shandura, kana kumisa kurapwa kunogona kunge kuchibva pamhedzisiro yeiyi bvunzo.

Mimwe bvunzo ichaenderera ichiitwa nguva nenguva mushure mekunge kurapwa kwapera. Mhedzisiro yeiyi bvunzo inogona kuratidza kana mamiriro ako achinja kana kana gomarara radzoka (dzoka). Iyi bvunzo dzimwe nguva inonzi yekuteedzera-bvunzo kana kuongorora-kumusoro.

Kurapa Sarudzo dzePuraimari CNS Lymphoma

Muchikamu chino

• Yekutanga CNS Lymphoma

• Yekutanga Intraocular Lymphoma

• Dzokororo Primary CNS Lymphoma

Kuti uwane ruzivo nezve marapirwo akanyorwa pazasi, ona iyo Chikamu Sarudzo Yekutarisa Chikamu.

Yekutanga CNS Lymphoma

Kurapa kwepakutanga central nervous system (CNS) lymphoma inogona kusanganisira zvinotevera:

• Uropi hwese radiation radiation.

• Chemotherapy.

• Chemotherapy inoteverwa ne radiation radiation.

• Chemotherapy uye yakanangwa kurapa (rituximab) inoteverwa neiyo yepamusoro-dose chemotherapy uye stem cell kuisirwa.

• Kuongororwa kwekiriniki yeakakwira-dose chemotherapy ne stem cell transplant.

• Kuongororwa kwekiriniki yeakakwira-dose chemotherapy uye yakanangwa kurapwa (rituximab), iine kana isina stem cell yekuisa kana iyo yakazara yeuropi radiation radiation.

Yekutanga Intraocular Lymphoma

Kurapa kwepakutanga intraocular lymphoma kunogona kusanganisira zvinotevera:

• Chemotherapy (intraocular kana systemic).

• Uropi hwese radiation radiation.

Dzokororo Primary CNS Lymphoma

Kurapa kweakajairika epakati epakati system system (CNS) lymphoma inogona kusanganisira zvinotevera:

• Chemotherapy.

• Radiation therapy (kana isina kugamuchirwa mukurapa kwekutanga).

• Kuongororwa kwekiriniki yemushonga mutsva kana chirongwa chekurapa.

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Kuti Udzidze Zvakawanda NezvePuraimari CNS Lymphoma

Kuti uwane rumwe ruzivo kubva kuNational Cancer Institute nezve yekutanga CNS lymphoma, ona zvinotevera:

• Lymphoma Kumba Peji

Kuti uwane ruzivo rwekenza uye zvimwe zviwanikwa kubva kuNational Cancer Institute, ona zvinotevera:

• Nezve Kenza

• Stage

• Chemotherapy uye Iwe: Tsigiro Yevanhu Vane Kenza

• Radiation Therapy uye Iwe: Rutsigiro rweVanhu Vane Kenza

• Kurarama neCancer

• Mibvunzo Yekubvunza Wako Chiremba nezveCancer

• Kune Vakapona uye Vanotarisira