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Chisingaperi Myelogenous Leukemia Kurapa (®) -Patient Shanduro

General Ruzivo nezve Chisingaperi Myelogenous Leukemia

PFUNGWA DZINOKOSHA

• Chisingaperi myelogenous leukemia chirwere umo mapfupa emapfupa anoita akawandisa machena masero eropa.

• Leukemia inogona kukanganisa masero matsvuku eropa, machena masero eropa, uye maplatelet.

• Zviratidzo nezviratidzo zvechirwere chisingaperi chinosanganisira leukemia inosanganisira kupisa muviri, kudikitira usiku, uye kuneta.

• Vazhinji vanhu vane CML vane geni mutation (shanduko) inonzi Philadelphia chromosome.

• Kuyedza kunoongorora ropa nemwongo wemapfupa kunoshandiswa kuona (kuwana) uye kuongorora chirwere chemeukemia chisingaperi.

• Zvimwe zvinhu zvinokanganisa kufungidzira (mukana wekupora) uye sarudzo dzekurapa.

Chisingaperi myelogenous leukemia chirwere umo mapfupa emapfupa anoita akawandisa machena masero eropa.

Chisingaperi myelogenous leukemia (inonziwo CML kana chisingaperi granulocytic leukemia) irikurwara zvishoma nezvishoma ropa uye mapfupa emongo izvo zvinowanzoitika mukati kana mushure mezera repakati, uye zvisingawanzo kuitika muvana.

Anatomy yebhonzo. Bhonzo rinoumbwa necompact bone, spongy bone, uye mwongo wefupa. Compact bone rinoumba chikamu chekunze chepfupa. Spongy bone rinowanikwa zvakanyanya kumagumo emabhonzo uye rine mutsvuku. Bhonzo remapfupa rinowanikwa pakati pemapfupa mazhinji uye rine tsinga zhinji dzeropa. Kune mhando mbiri dzemongo wemapfupa: tsvuku uye yero. Mutsvuku mutsvuku une masero eropa anogona kuve masero matsvuku eropa, machena masero eropa, kana maplatelet. Yero mwongo inogadzirwa kazhinji yemafuta.

Leukemia inogona kukanganisa masero matsvuku eropa, machena masero eropa, uye maplatelet.

Kazhinji, mwongo wemapfupa unoita maseru eropa (maseru asina kukura) anova masero eropa akakura nekufamba kwenguva. Sero reropa rinogona kuva myeloid stem cell kana lymphoid stem cell. Lymhoid stem cell rinova jena reropa jena.

Iyo myeloid stem sero inova imwe yemhando nhatu dzemasero eropa akura:

• Masero matsvuku eropa anotakura okisijeni nezvimwe zvinhu kumatishu ese emuviri.

• Maplatelet ayo anogadzira ropa kuwacha kubuda ropa.

• Granulocytes (machena masero eropa) ayo anorwisa hutachiona nezvirwere.

Ropa masero kukura. Sero reropa rinopinda nematanho akati wandei kuti riite tsvuku reropa, platelet, kana chena reropa.

MuCML, masero eropa akawandisa anova mhando yesero reropa jena rinonzi granulocytes. Aya ma granulocyte haana kujairika uye haaite maseru machena ane hutano. Iwo anonziwo maseru eukemia. Masero eleukemia anogona kuvaka muropa uye mwongo wemapfupa saka pane nzvimbo shoma yemasero machena eropa, masero matsvuku eropa, uye maplatelet. Kana izvi zvikaitika, hutachiona, kupererwa neropa, kana kubuda ropa nyore zvinogona kuitika.

Iyi pfupiso iri pamusoro pechirwere chisingaperi chine myelogenous leukemia. Ona zvinotevera pfupiso dze kuti uwane rumwe ruzivo nezve leukemia:

• Vakuru Acute Lymphoblastic Leukemia Kurapa

• Zvepwere Acute Lymphoblastic Leukemia Kurapa

• Vakuru Acute Myeloid Leukemia Kurapa

• Zvepwere Acute Myeloid Leukemia / Imwe Myeloid Malignancies Kurapa

• Chisingaperi Lymphocytic Leukemia Kurapa

• Bvudzi Cell Leukemia Kurapa

Zviratidzo nezviratidzo zvechirwere chisingaperi chinosanganisira leukemia inosanganisira kupisa muviri, kudikitira usiku, uye kuneta.

Izvi nezvimwe zviratidzo uye zviratidzo zvinogona kukonzerwa neCML kana nemamwe mamiriro. Tarisa nachiremba wako kana iwe uine chero chinotevera:

• Kunzwa kuneta chaizvo.

• Kurera huremu pasina chikonzero chinozivikanwa.

• Night sweats.

• Kupindwa nechando.

• Marwadzo kana kunzwa kwekuzara pazasi pembabvu kuruboshwe.

• Dzimwe nguva CML haina kukonzera chero zviratidzo zvachose.

Vazhinji vanhu vane CML vane geni mutation (shanduko) inonzi Philadelphia chromosome.

Sero rega rega mumuviri rine DNA (genetic material) inosarudza kuti sero rinotaridzika sei uye rinoita sei. DNA inowanikwa mukati memakromosomes. MuCML, chikamu cheDNA kubva kune imwe chromosome inoenda kune imwe chromosome. Shanduko iyi inonzi "Philadelphia chromosome." Zvinoguma nemongo wemapfupa uchigadzira puroteni, inonzi tyrosine kinase, iyo inokonzeresa maseru maseru akawandisa kuita maseru eropa (granulocytes kana kuputika).

Iyo chromosome yePhiladelphia haina kupfuudzwa kubva kumubereki kuenda kumwana.

Philadelphia chromosome. Chidimbu chechromosome 9 uye chidimbu chekromosome 22 chinoputsa uye nzvimbo dzekutengesa. Iyo BCR-ABL gene inoumbwa pane chromosome 22 apo chidimbu che chromosome 9 chinonamira. Iyo yakachinja chromosome 22 inonzi iyo Philadelphia chromosome.

Kuyedza kunoongorora ropa nemwongo wemapfupa kunoshandiswa kuona (kuwana) uye kuongorora chirwere chemeukemia chisingaperi.

Iyi inotevera bvunzo uye maitiro anogona kushandiswa:

Kuongorora kwemuviri uye nhoroondo yehutano: Kuongorora kwemuviri kutarisa zviratidzo zvehutano, kusanganisira kutarisa zviratidzo zvehosha senge yakawedzera spleen. Nhoroondo yemaitiro ehutano hwemurwere uye kurwara kwakapfuura uye kurapwa kuchatorwawo.

Yakazara huwandu hweropa (CBC) nemusiyano: Maitiro umo muyenzaniso weropa unodhonzwa nekuongororwa zvinotevera:

• Huwandu hwemasero matsvuku eropa nemaplatelet.

• Nhamba uye mhando yemasero machena eropa.

• Huwandu hwehemoglobin (protein inotakura oxygen) mumasero matsvuku eropa.

• Chikamu chemuenzaniso weropa chakaumbwa nemasero matsvuku eropa.

Yakazara kuverenga ropa (CBC). Ropa rinounganidzwa nekupinza tsono mutsinga uye richiita kuti ropa riyerere muhubhu. Muenzaniso weropa unotumirwa murabhoritari uye masero matsvuku eropa, masero machena eropa, uye maplatelet anoverengwa. Iyo CBC inoshandiswa kuyedza, kuongorora, uye kuongorora akawanda mamiriro akasiyana.

• Ropa kemesitiri zvidzidzo: Maitiro umo muyedzo weropa unoongororwa kuyera huwandu hwezvimwe zvinhu zvakaburitswa muropa nenhengo uye nyama munyama. Chinhu chisina kujairika (chakakwirira kana chakaderera pane zvakajairwa) chiyero chechinhu chinogona kunge chiri chiratidzo chechirwere.

• Bone marrow aspiration uye biopsy: Kubviswa kwemongo wemapfupa, ropa, uye chidimbu chefupa nekuisa tsono muchiuno kana muchifuva. Nyanzvi yezvirwere anoona pfupa, ropa, uye pfupa pasi pe microscope kutsvaga masero asina kujairika.

Bone marora chishuwo uye biopsy. Mushure mekunge nzvimbo diki yeganda yave nechiveve, tsono yemongo wemapfupa inoiswa mupfupa rehudyu remurwere. Samples reropa, bhonzo, uye mwongo wemapfupa zvinobviswa kuti zviongororwe pasi pe microscope.

Imwe yeiyi miedzo inotevera inogona kuitwa pane sampuli yeropa kana yemwongo yemapfupa inobviswa.

• Kuongorora kweCytogenetic: Kuongororwa kwerabhoritari umo ma chromosomes emaseru mune muyenzaniso weropa kana mongo wemapfupa anoverengwa uye kuongororwa chero shanduko, sekutyorwa, kushaikwa, kurongedzwa patsva, kana mamwe ma chromosomes. Shanduko mune mamwe ma chromosomes, senge chromosome yePhiladelphia, inogona kunge iri chiratidzo checancer. Kuongorora kweCytogenetic kunoshandiswa kubatsira kuongorora cancer, kuronga kurapwa, kana kuona kuti kurapa kuri kushanda sei.

• FISH (fluorescence in situ hybridization): Kuedzwa kwerabhoritari kunoshandiswa kutarisa uye kuverenga majeni kana ma chromosomes mumasero nematukisi. Zvidimbu zveDNA zvine dhayi ye fluorescent zvinogadzirwa murabhoritari uye zvinowedzerwa kune imwe sampuli yemasero emurwere kana zvinyama. Kana zvidimbu izvi zvakavezwa zveDNA zvonamatira kune mamwe mageneti kana nzvimbo dzekromosomes mumuenzaniso, dzinovhenekera kana dzatariswa pasi pefluorescent microscope. Chiyero cheFISH chinoshandiswa kubatsira kuongorora gomarara uye kubatsira kuronga kurapwa.

• Reverse transcript- polymerase chain reaction test (RT – PCR): Kuongororwa kwerabhoritari umo huwandu hwechibereko chinonzi mRNA chakagadzirwa neimwe geni chinoyerwa. Enzyme inonzi reverse transcriptase inoshandiswa kushandura chidimbu cheRNA kuita chidimbu cheDNA, icho chinogona kukwidziridzwa (chakaitwa muzvizhinji) neimwe enzyme inonzi DNA polymerase. Akawedzeredzwa maDNA makopi anobatsira kutaurira kana chaiyo mRNA iri kugadzirwa negene. RT-PCR inogona kushandiswa kuongorora kumisikidza kwemamwe majeni anogona kuratidza kuvapo kwemasero ekenza. Iyi bvunzo inogona kushandiswa kutsvaga kumwe kuchinjika mugene kana chromosome, iyo inogona kubatsira kuongorora kenza.

Zvimwe zvinhu zvinokanganisa kufungidzira (mukana wekupora) uye sarudzo dzekurapa.

Kufungidzira (mukana wekupora) uye sarudzo dzekurapa dzinoenderana nezvinotevera:

• zera remurwere.

• Chikamu cheCML.

• Kuwanda kwekuputika muropa kana pfupa remongo.

• Kukura kwepleen pakuongororwa.

Matanho eChisingaperi Myelogenous Leukemia

PFUNGWA DZINOKOSHA

• Mushure mokunge myelogenous leukemia isingaperi yaonekwa, kuongororwa kunoitwa kuti uone kana gomarara rapararira.

• Chisingaperi myelogenous leukemia ine zvikamu zvitatu.

• Chikamu chisingaperi

• Yakawedzera chikamu

• Blastic chikamu

• Hutano hwese hwemurwere.

Mushure mokunge myelogenous leukemia isingaperi yaonekwa, kuongororwa kunoitwa kuti uone kana gomarara rapararira.

Staging ndiyo nzira inoshandiswa kuziva kuti kenza yapararira zvakadii. Iko hakuna standard standard staging system ye chisingaperi myelogenous leukemia (CML). Panzvimbo iyoyo, chirwere chinosarudzwa nechikamu: chisingaperi chikamu, chinokurumidza chikamu, kana chikamu cheblastic. Izvo zvakakosha kuti uzive chikamu kuitira kuronga kurapwa. Ruzivo kubva kuongororo nemaitiro akaitwa kuti aone (tsvaga) uye kuongorora chirwere chisingaperi chemelouks chinoshandiswa kuronga kurapwa.

Chisingaperi myelogenous leukemia ine zvikamu zvitatu.

Sezvo huwandu hwekuputika maseru huchiwedzera muropa nemongo wemapfupa, pane nzvimbo shoma yemasero eropa ane hutano, masero matsvuku eropa, uye maplatelet. Izvi zvinogona kukonzera kutapukirwa, kupererwa neropa, uye kubuda ropa nyore, pamwe nekurwadziwa kwepfupa uye kurwadziwa kana kunzwa kwekuzara pazasi pembabvu kuruboshwe. Huwandu hwekuputika kwemasero muropa uye mwongo wemapfupa uye kuomarara kwezviratidzo kana zviratidzo zvinoratidza chikamu chechirwere.

Chikamu chisingaperi

Muchikamu chisingaperi CML, mashoma pane gumi muzana emasero muropa uye mwongo wemapfupa ndiwo anoputika maseru.

Yakawedzera chikamu

Muchikamu chinokurumidza CML, 10% kusvika 19% yemasero ari muropa uye mwongo wemapfupa masero ekuputika.

Blastic chikamu

Muchikamu che blastic CML, makumi maviri muzana kana mamwe masero ari muropa kana mwongo wemapfupa masero ekuputika. Kana kuneta, fivhiri, uye yakawedzera spleen ichiitika panguva yekutsvaira chikamu, inonzi kuputika dambudziko.

Kudzokazve Kusingaperi kweMyelogenous Leukemia

Mune yakadzokororwa CML, huwandu hwekuputika maseru hunowedzera mushure mekuregererwa.

Kurapa Sarudzo Kuongorora

PFUNGWA DZINOKOSHA

• Kune akasiyana marudzi ekurapa kwevarwere vane chisingaperi myelogenous leukemia.

• Mhando nhanhatu dzekurapwa kwakajairika dzinoshandiswa:

• Targeted kurapwa

• Chemotherapy

• Biologic kurapa

• Yakakwira-dose chemotherapy ine stem cell yekuisa

• Anopa lymphocyte infusion (DLI)

• Kuvhiya

• Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

• Kurapa kwechirwere chisingaperi chingaita leukemia kunogona kukonzera mhedzisiro.

• Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

• Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kenza kurapwa.

• Yekutevera-bvunzo inogona kudikanwa.

Kune akasiyana marudzi ekurapa kwevarwere vane chisingaperi myelogenous leukemia.

Mhando dzakasiyana dzekurapa dzinowanikwa kune varwere vane chisingaperi myelogenous leukemia (CML). Mamwe marapirwo akajairwa (iko kurapwa kwazvino kwashandiswa), uye kumwe kuedzwa mumakiriniki ekuedzwa A kurapwa kiriniki kuyedzwa chidzidzo chekutsvaga chakaitirwa kubatsira kuvandudza marapirwo azvino kana kuwana ruzivo nezve marapirwo matsva evarwere vane gomarara. Kana kiriniki miedzo ikaratidza kuti kurapwa kutsva kuri nani pane kwese kurapwa, kurapwa kutsva kunogona kuve kwakajairwa kurapwa. Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki. Mimwe miedzo yekiriniki yakavhurwa chete kune varwere vasina kutanga kurapwa.

Mhando nhanhatu dzekurapwa kwakajairika dzinoshandiswa:

Targeted kurapwa

Targeted therapy mhando yekurapa inoshandisa zvinodhaka kana zvimwe zvinhu kuti zvione uye kurwisa chaiwo maseru ekenza pasina kukuvadza zvakajairika maseru. Tyrosine kinase inhibitors inotarisirwa kurapa zvinodhaka zvinoshandiswa kurapa chisingaperi myelogenous leukemia.

Imatinib mesylate, nilotinib, dasatinib, uye ponatinib ndeye tyrosine kinase inhibitors ayo anoshandiswa kurapa CML.

Maona Zvinodhakwa Zvinotenderwa Zvechirwere Chisingaperi Chingangoitika neropa.

Chemotherapy

Chemotherapy mushonga wekenza unoshandisa mishonga kumisa kukura kwemasero ekenza, kungave nekuuraya maseru kana nekuamisa iwo kubva pakupatsanuka. Kana chemotherapy ikatorwa nemuromo kana kujowa mutsinga kana mhasuru, mishonga inopinda muropa uye inogona kusvika masero emukenza mumuviri wese (systemic chemotherapy). Kana chemotherapy ikaiswa yakanangana necerebrospinal fluid, nhengo, kana dumbu remuviri senge dumbu, iwo madhiragi anonyanya kukanganisa cancer maseru munzvimbo idzodzo (remunharaunda chemotherapy). Nzira iyo chemotherapy inopihwa inoenderana nerudzi uye nhanho yekenza iri kurapwa.

Maona Zvinodhakwa Zvinotenderwa Zvechirwere Chisingaperi Chingangoitika neropa.

Biologic kurapa

Biologic kurapa kurapwa kunoshandisa immune system yemurwere kurwisa gomarara. Zvinhu zvinogadzirwa nemuviri kana kugadzirwa murabhoritari zvinoshandiswa kusimudzira, kunongedza, kana kudzorera kudzivirira kwemuviri kurwisa kenza. Rudzi rwekurapa kenza urwu rwunonziwo biotherapy kana immunotherapy.

Maona Zvinodhakwa Zvinotenderwa Zvechirwere Chisingaperi Chingangoitika neropa.

Yakakwira-dose chemotherapy ine stem cell yekuisa

Yakakwira madosi ekemotherapy anopiwa kuuraya cancer maseru. Masero ane hutano, kusanganisira masero anogadzira ropa, anoparadzwa nekenza kurapwa. Stem cell transplant kurapwa kwekutsiva maseru anogadzira ropa. Masero emashizha (masero eropa asina kusimba) anobviswa muropa kana mwongo wemapfupa emurwere kana mupi uye anoomeswa nechando. Mushure mekunge murwere apedza chemotherapy, maseru akachengetwa anonyungudutswa uye ndokudzoserwa kumurwere kuburikidza nekumukiswa. Aya akadzikiswa maseru emadzinde anokura kuita (uye kudzoreredza) masero eropa emuviri.

Maona Zvinodhakwa Zvinotenderwa Zvechirwere Chisingaperi Chingangoitika neropa.

Stem cell kuisirwa. (Nhanho 1): Ropa rinotorwa kubva mutsinga iri muruoko rweanopa. Murwere kana mumwe munhu angave ari mupi. Ropa rinoyerera nemuchina unobvisa masero emadzinde. Ipapo iro ropa rinodzoserwa kune anenge apa kuburikidza netsinga iri mune rumwe ruoko. (Nhanho 2): Murwere anogamuchira chemotherapy kuuraya masero anogadzira ropa. Murwere anogona kupihwa radiation radiation (isina kuratidzwa). (Nhanho 3): Murwere anogamuchira masero emadzinde kuburikidza nekateti yakaiswa mumudziyo weropa muchipfuva.

Anopa lymphocyte infusion (DLI)

Donor lymphocyte infusion (DLI) kurapwa kwekenza kunogona kushandiswa mushure mekudzikiswa kwesero. MaLymphocyte (rudzi rweye chena yeropa) kubva kune iyo stem cell yekuisa mupi inobviswa muropa remupi uye inogona kuve yakaoma nechando yekuchengetedza. Ma lymphocyte emupi wemupi anonyungudutswa kana akaomeswa nechando obva apihwa kumurwere kubudikidza nekumwe infusions. Iwo maLymphocyte anoona maseru ekenza emurwere seasiri emuviri uye anovarwisa.

Kuvhiya

Splenectomy kuvhiyiwa kubvisa iyo spleen.

Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

Ruzivo nezve kiriniki miedzo inowanikwa kubva kuNCI webhusaiti.

Kurapa kwechirwere chisingaperi chingaita leukemia kunogona kukonzera mhedzisiro.

Kuti uwane ruzivo nezve mhedzisiro inokonzerwa nekurapwa kwegomarara, ona yedu Side Mhedzisiro peji.

Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

Kune vamwe varwere, kutora chikamu mumuedzo wekiriniki inogona kunge iri sarudzo yekurapa yakanyanya kunaka. Kliniki miedzo chikamu chekenza tsvagiridzo. Zvemakiriniki miedzo inoitwa kuti uone kana marapirwo matsva egomarara akachengeteka uye achishanda kana zvirinani pane akajairwa kurapwa.

Mazhinji emazuva ano marapirwo akajairwa ekenza akavakirwa pamavambo emakiriniki ekuedzwa. Varwere vanotora chikamu mukuyedzwa kwekiriniki vanogona kuwana kurapwa kwakaringana kana kuve pakati pevekutanga kurapwa kutsva.

Varwere vanotora chikamu mumiedzo yekiriniki zvakare vanobatsira kugadzirisa marapirwo achaitwa kenza mune ramangwana. Kunyangwe kana miedzo yemakiriniki isinga tangire kumarapirwo matsva anoshanda, anowanzo pindura mibvunzo yakakosha uye anobatsira kufambisira mberi kutsvagurudza.

Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kenza kurapwa.

Mimwe miedzo yekiriniki inosanganisira chete varwere vasati vagamuchira kurapwa. Mimwe miedzo yekuedza kurapwa kwevarwere vane kenza haina kuve nani. Kune mamwezve emakiriniki miedzo inoedza nzira nyowani dzekumisa cancer kubva kudzokororazve (kudzoka) kana kudzikisira mhedzisiro yemakenza kurapwa.

Kuedzwa kwemakiriniki kuri kuitika munzvimbo zhinji dzenyika. Ruzivo nezve kiriniki miedzo inotsigirwa neNCI inogona kuwanikwa paNCI yekiriniki miedzo yekutsvaga peji rewebhu. Kliniki miedzo inotsigirwa nemamwe masangano inogona kuwanikwa pane yeClinicalTrials.gov webhusaiti.

Yekutevera-bvunzo inogona kudikanwa.

Mimwe miedzo yakaitwa kuongorora gomarara kana kutsvaga danho rekenza inogona kudzokororwa. Dzimwe bvunzo dzinodzokororwa kuitira kuti vaone kuti kurapa kuri kushanda sei. Sarudzo nezvekuti uenderere mberi, shandura, kana kumisa kurapwa kunogona kunge kuchibva pamhedzisiro yeiyi bvunzo.

Mimwe bvunzo ichaenderera ichiitwa nguva nenguva mushure mekunge kurapwa kwapera. Mhedzisiro yeiyi bvunzo inogona kuratidza kana mamiriro ako achinja kana kana gomarara radzoka (dzoka). Iyi bvunzo dzimwe nguva inonzi yekuteedzera-bvunzo kana kuongorora-kumusoro.

Kurapa Sarudzo dzeKusingaperi Myelogenous Leukemia

Muchikamu chino

• Chisingaperi Chikamu Chisingaperi Chinoonekwa neMeukemia

• Yakawedzera Phase Chisingaperi Myelogenous Leukemia

• Blastic Phase Chisingaperi Myelogenous Leukemia

• Kudzokazve Kusingaperi kweMyelogenous Leukemia

Kuti uwane ruzivo nezve marapirwo akanyorwa pazasi, ona iyo Chikamu Sarudzo Yekutarisa Chikamu.

Chisingaperi Chikamu Chisingaperi Chinoonekwa neMeukemia

Kurapa kwechirwere chisingaperi chisingaperi myelogenous leukemia kunogona kusanganisira zvinotevera:

• Targeted Therapy ine tyrosine kinase inhibitor.

• Yakakwira-dose chemotherapy neyeanopa stem cell yekuisa.

• Chemotherapy.

• Splenectomy.

• Kuongororwa kwekiriniki kwepazasi-chemotherapy chemotherapy neanopa stem cell yekuisa.

• Kuongororwa kwekiriniki kwekurapwa kutsva.

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Yakawedzera Phase Chisingaperi Myelogenous Leukemia

Kurapa kwechimbichimbi chikamu chisingaperi myelogenous leukemia kunogona kusanganisira zvinotevera:

• Donor stem cell yekuisa.

• Targeted Therapy ine tyrosine kinase inhibitor.

• Tyrosine kinase inhibitor therapy inoteverwa neanopa stem cell yekuisa.

• Biologic therapy (interferon) ine kana isina chemotherapy.

• Yakakwira-dose chemotherapy.

• Chemotherapy.

• Kurapa kwekuisira kutsiva masero matsvuku eropa, maplatelet, uye dzimwe nguva masero machena eropa, kubvisa zviratidzo uye nekuvandudza hupenyu.

• Kuongororwa kwekiriniki kwekurapwa kutsva.

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Blastic Phase Chisingaperi Myelogenous Leukemia

Kurapa kweblastic phase chisingaperi myelogenous leukemia kunogona kusanganisira zvinotevera:

• Targeted Therapy ine tyrosine kinase inhibitor.

• Chemotherapy kushandisa imwe kana akawanda madhiragi.

• Yakakwira-dose chemotherapy.

• Donor stem cell yekuisa.

• Chemotherapy senzira yekurapa yekurapa kubvisa zviratidzo uye nekuvandudza hupenyu.

• Kuongororwa kwekiriniki kwekurapwa kutsva.

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Kudzokazve Kusingaperi kweMyelogenous Leukemia

Kurapa kwekudzokazve kusingaperi kwemoyeloousous leukemia kunogona kusanganisira zvinotevera:

• Targeted Therapy ine tyrosine kinase inhibitor.

• Donor stem cell yekuisa.

• Chemotherapy.

• Anopa lymphocyte infusion.

• Biologic kurapa (interferon).

• Kuongororwa kwekiriniki yemhando nyowani kana mizinga yepamusoro yekurapa kwakanangwa kana wevanopa stem cell yekuisa.

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Kuti Udzidze Zvakawanda Nezve Chisingaperi Myelogenous Leukemia

Kuti uwane rumwe ruzivo kubva kuNational Cancer Institute nezve chisingaperi myelogenous leukemia, ona zvinotevera:

• Leukemia Peji Peji

• Targeted Cancer Therapies

• Mishonga Inogamuchirwa Yechisingaperi Meelogenous Leukemia

• Zvinodhaka Zvinotenderwa zveMyeloproliferative Neoplasms

• Immunotherapy Kurapa Cancer

• Ropa-Richigadzira Stem Cell Inoshandura

Kuti uwane ruzivo rwekenza uye zvimwe zviwanikwa kubva kuNational Cancer Institute, ona zvinotevera:

• Nezve Kenza

• Stage

• Chemotherapy uye Iwe: Tsigiro Yevanhu Vane Kenza

• Radiation Therapy uye Iwe: Rutsigiro rweVanhu Vane Kenza

• Kurarama neCancer

• Mibvunzo Yekubvunza Wako Chiremba nezveCancer

• Kune Vakapona uye Vanotarisira