Types/leukemia/patient/cll-treatment-pdq

Chisingaperi Lymphocytic Leukemia Kurapa (®) -Patient Shanduro

General Ruzivo nezve Chisingaperi Lymphocytic Leukemia

PFUNGWA DZINOKOSHA

• Chronic lymphocytic leukemia rudzi rwegomarara umo mwongo wemapfupa unogadzira ma lymphocyte akawandisa (rudzi rwechena reropa).

• Leukemia inogona kukanganisa masero matsvuku eropa, machena masero eropa, uye maplatelet.

• Kuchembera kunogona kukanganisa njodzi yekukura kwenguva refu lymphocytic leukemia.

• Zviratidzo uye zviratidzo zvechisingaperi lymphocytic leukemia zvinosanganisira kuzvimba lymph node uye kuneta.

• Kuyedza kunoongorora iro ropa, mwongo wemapfupa, uye lymph node zvinoshandiswa kuongorora chisingaperi cheLymphocytic leukemia.

• Zvimwe zvinhu zvinokanganisa sarudzo dzekurapa uye kufungidzira (mukana wekupora).

Chronic lymphocytic leukemia rudzi rwegomarara umo mwongo wemapfupa unogadzira ma lymphocyte akawandisa (rudzi rwechena reropa).

Chirwere cheLymphocytic leukemia (inonziwo CLL) chirwere cheropa uye chepfupa iro rinowanzo kukura zvishoma nezvishoma. CLL ndeimwe yemhando dzakajairika dzeleukemia muvanhu vakuru. Inowanzoitika mukati kana mushure mezera repakati; hazviwanzo kuitika muvana.

Anatomy yebhonzo. Bhonzo rinoumbwa necompact bone, spongy bone, uye mwongo wefupa. Compact bone rinoumba chikamu chekunze chepfupa. Spongy bone rinowanikwa zvakanyanya kumagumo emabhonzo uye rine mutsvuku. Bhonzo remapfupa rinowanikwa pakati pemapfupa mazhinji uye rine tsinga zhinji dzeropa. Kune mhando mbiri dzemongo wemapfupa: tsvuku uye yero. Mutsvuku mutsvuku une masero eropa anogona kuve masero matsvuku eropa, machena masero eropa, kana maplatelet. Yero mwongo inogadzirwa kazhinji yemafuta.

Leukemia inogona kukanganisa masero matsvuku eropa, machena masero eropa, uye maplatelet. Kazhinji, muviri unogadzira maseru masero eropa (maseru asina kukura) anova masero eropa akakura nekufamba kwenguva. Sero reropa rinogona kuva myeloid stem cell kana lymphoid stem cell.

Iyo myeloid stem sero inova imwe yemhando nhatu dzemasero eropa akura:

• Masero matsvuku eropa anotakura okisijeni nezvimwe zvinhu kumatishu ese emuviri.

• Masero machena eropa anorwisa hutachiona nezvirwere.

• Maplatelet ayo anogadzira ropa kuwacha kubuda ropa.

A lymphoid stem cell inova lymphoblast cell uyezve imwe yemhando nhatu dze lymphocyte (machena masero eropa):

• B ma lymphocyte anogadzira masoja ekudzivirira chirwere.

• T lymphocyte dzinobatsira B lymphocyte kugadzira masoja ekudzivirira hutachiona.

• Maseru anouraya chaiwo anorwisa cancer maseru uye hutachiona.

Ropa masero kukura. Sero reropa rinopinda nematanho akati wandei kuti riite tsvuku reropa, platelet, kana chena reropa.

MuCLL, akawanda maseru eropa masero anova asina kujairika maLymphocyte uye haaite machena machena masero eropa. Izvo zvisina kujairika lymphocyte zvinogona zvakare kunzi leukemia maseru. Iwo maLymphocyte haakwanise kurwisa hutachiona zvakanyanya. Zvakare, sezvo huwandu hwema lymphocyte huchiwedzera muropa nemongo wemapfupa, pane nzvimbo shoma yemasero eropa ane hutano, masero matsvuku eropa, uye maplatelet. Izvi zvinogona kukonzera hutachiona, kupererwa neropa, uye nyore kubuda ropa.

Ichi chidimbu chiri pamusoro pechirwere cheLymphocytic leukemia. Ona zvinotevera pfupiso dze kuti uwane rumwe ruzivo nezve leukemia:

• Vakuru Acute Lymphoblastic Leukemia Kurapa.

• Zvepwere Acute Lymphoblastic Leukemia Kurapa.

• Vakuru Acute Myeloid Leukemia Kurapa.

• Zvepwere Acute Myeloid Leukemia / Imwe Myeloid Malignancies Kurapa.

• Chisingaperi Myelogenous Leukemia Kurapa.

• Bvudzi Cell Leukemia Kurapa.

Kuchembera kunogona kukanganisa njodzi yekukura kwenguva refu lymphocytic leukemia.

Chero chipi zvacho chinowedzera njodzi yako yekuwana chirwere chinonzi njodzi chinhu. Kuva nenjodzi hazvireve kuti uchawana gomarara; kusava nenjodzi hazvireve kuti hauzobatwe negomarara. Taura nachiremba wako kana iwe uchifunga kuti ungave uri panjodzi. Njodzi zvinhu zveCLL zvinosanganisira zvinotevera:

• Kuve wepakati-zera kana mukuru, murume, kana chena.

• Nhoroondo yemhuri yeCLL kana kenza yeiyo lymph system.

• Kuva nehama dziri maRussia maRussia kana maEastern Europe maJuda.

Zviratidzo uye zviratidzo zvechisingaperi lymphocytic leukemia zvinosanganisira kuzvimba lymph node uye kuneta.

Kazhinji CLL haina kukonzera chero zviratidzo kana zviratidzo uye inowanikwa panguva yekujairirwa kweropa. Zviratidzo nezviratidzo zvinogona kukonzerwa neCLL kana nemamwe mamiriro. Tarisa nachiremba wako kana iwe uine chero chinotevera:

• Kuzvimba kusingarwadzi kwema lymph node mumutsipa, underarm, mudumbu kana kugomera.

• Kunzwa kuneta chaizvo.

• Marwadzo kana kuzara pazasi pembabvu.

• Fivha uye hutachiona.

• Kurera huremu pasina chikonzero chinozivikanwa.

Kuyedza kunoongorora iro ropa, mwongo wemapfupa, uye lymph node zvinoshandiswa kuongorora chisingaperi cheLymphocytic leukemia.

Iyi inotevera bvunzo uye maitiro anogona kushandiswa:

• Kuongorora kwemuviri uye nhoroondo yehutano: Kuongororwa kwemuviri kutarisa zviratidzo zvehutano, kusanganisira kuongorora zviratidzo zvehosha, zvakadai semapundu kana chero chinhu chinoratidzika sechisina kujairika. Nhoroondo yemaitiro ehutano hwemurwere uye kurwara kwakapfuura uye kurapwa kuchatorwawo.

• Yakazara huwandu hweropa (CBC) nemusiyano: Maitiro umo muyenzaniso weropa unodhonzwa nekuongororwa zvinotevera:

• Huwandu hwemasero matsvuku eropa nemaplatelet.

• Nhamba uye mhando yemasero machena eropa.

• Huwandu hwehemoglobin (protein inotakura oxygen) mumasero matsvuku eropa.

• Chikamu chemuenzaniso weropa chakaumbwa nemasero matsvuku eropa.

Yakazara kuverenga ropa (CBC). Ropa rinounganidzwa nekupinza tsono mutsinga uye richiita kuti ropa riyerere muhubhu. Muenzaniso weropa unotumirwa murabhoritari uye masero matsvuku eropa, masero machena eropa, uye maplatelet anoverengwa. Iyo CBC inoshandiswa kuyedza, kuongorora, uye kuongorora akawanda mamiriro akasiyana.

• Immunophenotyping: Kuongororwa kwerabhoritari inoshandisa masoja ekudzivirira kenza maseru zvichibva pamhando dzemaantigen kana mamaki ari pamusoro pemasero. Iyi bvunzo inoshandiswa kubatsira kuongorora chaiwo marudzi eleukemia.

• FISH (fluorescence in situ hybridization): Kuedzwa kwerabhoritari kunoshandiswa kutarisa uye kuverenga majeni kana ma chromosomes mumasero nematukisi. Zvidimbu zveDNA zvine dhayi ye fluorescent zvinogadzirwa murabhoritari uye zvinowedzerwa kune imwe sampuli yemasero emurwere kana zvinyama. Kana zvidimbu izvi zvakavezwa zveDNA zvonamatira kune mamwe mageneti kana nzvimbo dzekromosomes mumuenzaniso, dzinovhenekera kana dzatariswa pasi pefluorescent microscope. Chiyero cheFISH chinoshandiswa kubatsira kuongorora gomarara uye kubatsira kuronga kurapwa.

• Kuyerera cytometry: Kuedzwa kwerabhoritari kunoyera huwandu hwamasero mune imwe sampuro, muzana yemasero mhenyu mune imwe sampuro, uye mamwe maitiro emaseru, senge saizi, chimiro, uye kuvepo kwethumba (kana zvimwe) mamaki pane sero pamusoro. Masero kubva pamuenzaniso weropa remurwere, mwongo wemapfupa, kana zvimwe zvinyama zvakasvibiswa nedhayi re fluorescent, rakaiswa mune mvura, uye ndokuzopfuura rimwe panguva kuburikidza nemwenje wechiedza. Mhedzisiro yekubvunzurudza inoenderana nekuti maseru aive akasvibiswa neiyo fluorescent dhayi anoita sei padanda rechiedza. Uyu muedzo unoshandiswa kubatsira kuongorora uye kubata mamwe marudzi ekenza, senge leukemia uye lymphoma.

• IgVH gene mutation testing: Kuongororwa kwerabhoritari umo muyedzo weropa kana munyama unoedzwa kune dzimwe shanduko muiyo IgVH geni. Varwere vane IgVH geni mutation vane fungidziro iri nani.

• Bone marrow aspiration uye biopsy: Kubviswa kwemongo wefupa, ropa, uye chidimbu chefupa nekuisa tsono isina mhango muhudyu kana pfupa rechipfuva. Nyanzvi yezvirwere anoona pfupa, ropa, uye pfupa pasi pe microscope kutsvaga masero asina kujairika.

Bone marora chishuwo uye biopsy. Mushure mekunge nzvimbo diki yeganda yave nechiveve, tsono yemongo wemapfupa inoiswa mupfupa rehudyu remurwere. Samples reropa, bhonzo, uye mwongo wemapfupa zvinobviswa kuti zviongororwe pasi pe microscope.

Zvimwe zvinhu zvinokanganisa sarudzo dzekurapa uye kufungidzira (mukana wekupora).

Kurapa sarudzo kunoenderana ne:

• Chikamu chehosha.

• Sero reropa dzvuku, chena ropa maseru, uye platelet reropa kuverenga.

vKunyangwe paine zviratidzo kana zviratidzo, zvakadai sefivhiri, kutonhora, kana kuonda.

• Kunyangwe chiropa, spleen, kana lymph node zvakakura kupfuura zvakajairwa.

• Mhinduro kurapa kwekutanga.

• Kunyangwe iyo CLL yadzokazve (dzoka).

Kufungidzira kunoenderana ne:

• Kunyangwe paine shanduko muDNA uye mhando yeshanduko, kana paine imwe.

• Kunyangwe ma lymphocyte akapararira mukati memafupa.

• Chikamu chehosha.

• Kunyangwe iyo CLL ichiita zvirinani nemushonga kana yadzokazve (dzoka).

• Kunyangwe iyo CLL ichifambira mberi kune lymphoma kana prolymphocytic leukemia.

• Zera remurwere uye hutano hwese.

Matanho eChronic Lymphocytic Leukemia

PFUNGWA DZINOKOSHA

• Mushure mokunge lymphocytic leukemia yaonekwa, kuongororwa kunoitwa kuti uone kuti kenza yapararira zvakadii muropa nemongo wemapfupa.

• Aya anotevera matanho anoshandiswa kune chisingaperi lymphocytic leukemia:

• Chikamu 0

• Chikamu I

• Chikamu II

• Chikamu chechitatu

• Chikamu IV

Mushure mokunge lymphocytic leukemia yaonekwa, kuongororwa kunoitwa kuti uone kuti kenza yapararira zvakadii muropa nemongo wemapfupa.

Staging ndiyo nzira inoshandiswa kuziva kuti kenza yapararira zvakadii. Izvo zvakakosha kuti uzive nhanho yechirwere kuitira kuronga kurapa kwakanyanya. Iyi miedzo inotevera inogona kushandiswa mukutora matanho:

• Chest x-ray: X-ray yenhengo nemapfupa mukati mechipfuva. X-ray rudzi rwechiyero chesimba chinogona kupfuura nemuviri uye kupinda mufirimu, ichigadzira mufananidzo wenzvimbo dziri mukati memuviri, senge ma lymph node.

• MRI (magnetic resonance imaging): Maitiro anoshandisa magineti, masaisai eredhiyo, uye komputa kugadzira yakateedzana mifananidzo yakajeka yenzvimbo dziri mukati memuviri, senge huropi uye musana. Iyi nzira inonziwo nyukireya magnetic resonance imaging (NMRI).

• CT scan (CAT scan): Maitiro anoita akateedzana emifananidzo yakajeka yenzvimbo dziri mukati memuviri, inotorwa kubva kumakona akasiyana. Mifananidzo yacho inogadzirwa nekombuta yakabatana neiyo x-ray muchina. Dhayi inogona kuiswa jekiseni kana kumedzwa kubatsira nhengo kana zvinyama kuratidza zvakajeka. Iyi nzira inonziwo computed tomography, computerized tomography, kana komputa axial tomography.

• PET-CT scan: Maitiro anosanganisa iyo mifananidzo kubva kune positron emission tomography (PET) scan uye computed tomography (CT) scan. Iyo PET neCT scan inoitwa panguva imwechete nemuchina mumwe chete. Izvo zviyero zvakasanganiswa zvinopa yakadzama mifananidzo yenzvimbo dziri mukati memuviri kupfuura chero scan inopihwa yega. PET scan ndiyo nzira yekuwana yakaipa malone maseru mumuviri. Chishoma che radioactive glucose (shuga) inoiswa mutsinga. Iyo PET scanner inotenderera yakatenderedza muviri uye inogadzira mufananidzo wepo glucose iri kushandiswa mumuviri. Malignant tumarara maseru anoratidza kupenya mumufananidzo nekuti anoshanda uye anotora glucose yakawanda kupfuura zvinoita maseru akajairwa.

• Ropa kemesitiri zvidzidzo: Maitiro umo muyedzo weropa unoongororwa kuyera huwandu hwezvimwe zvinhu zvakaburitswa muropa nenhengo uye nyama munyama. Chinhu chisina kujairika (chakakwirira kana chakaderera pane zvakajairwa) chiyero chechinhu chinogona kunge chiri chiratidzo chechirwere.

• Antiglobulin bvunzo: Chiyero umo muyenzaniso weropa unotariswa pasi pe microscope kuti uone kana paine chero maantibioti pamusoro pemasero matsvuku eropa kana maplatelet. Aya ma antibodies anogona kuita pamwe nekuparadza masero matsvuku eropa nemaplatelet. Uyu muedzo unonziwo muedzo weCombombs.

Aya anotevera matanho anoshandiswa kune chisingaperi lymphocytic leukemia:

Chikamu 0

Muchikamu che0 chisingagumi lymphocytic leukemia, kune ma lymphocyte akawandisa muropa, asi hapana zvimwe zviratidzo kana zviratidzo zve leukemia. Stage 0 chisingaperi lymphocytic leukemia haina indolent (inononoka-kukura).

Chikamu I

Muchikamu ini chisingaperi lymphocytic leukemia, kune ma lymphocyte akawandisa muropa uye ma "lymph node" akakura kupfuura zvakajairwa.

Chikamu II

Muchikamu chechipiri chisingagumi lymphocytic leukemia, kune ma lymphocyte akawandisa muropa, chiropa kana spleen yakakura kudarika zvakajairwa, uye ma "lymph node" anogona kuve akakura kupfuura akajairwa.

Chikamu chechitatu

Muchikamu chechitatu chisingagumi lymphocytic leukemia, kune ma lymphocyte akawandisa muropa uye kune mashoma masero matsvuku eropa. Iyo lymph node, chiropa, kana spleen inogona kunge yakakura kudarika zvakajairwa.

Chikamu IV

Muchikamu IV chisingagumi lymphocytic leukemia, kune ma lymphocyte akawandisa muropa uye maplatelet mashoma. Iyo lymph node, chiropa, kana spleen inogona kunge yakakura kudarika zvakajairwa uye panogona kunge paine mashoma masero matsvuku eropa.

Dzokororo kana Refractory Chirwere cheLymphocytic Leukemia

Yazvino isingagumi lymphocytic leukemia igomarara rakadzokazve (kudzoka), kazhinji mushure menguva yakati rebei panguva iyo cancer yaisaonekwa. Refractory chronic lymphocytic leukemia igomarara risinganatsirike pakurapwa.

Kurapa Sarudzo Kuongorora

PFUNGWA DZINOKOSHA

• Kune akasiyana marudzi ekurapa kwevarwere vane chisingaperi lymphocytic leukemia.

• Mhando shanu dzekurapwa kwakajairika dzinoshandiswa:

• Kurinda kumirira

• Radiation kurapa
• Chemotherapy

• Kuvhiya

• Targeted kurapwa

• Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

• Chemotherapy ne stem cell yekuisa

• Immunotherapy

• Kurapa kwechirwere cheLymphocytic leukemia kunogona kukonzera mhedzisiro.

• Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

• Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kenza kurapwa.

• Yekutevera-bvunzo inogona kudikanwa.

Kune akasiyana marudzi ekurapa kwevarwere vane chisingaperi lymphocytic leukemia.

Mhando dzakasiyana dzekurapa dzinowanikwa kune varwere vane chisingaperi lymphocytic leukemia. Mamwe marapirwo akajairwa (iko kurapwa kwazvino kwashandiswa), uye kumwe kuedzwa mumakiriniki ekuedzwa A kurapwa kiriniki kuyedzwa chidzidzo chekutsvaga chakaitirwa kubatsira kuvandudza marapirwo azvino kana kuwana ruzivo marapirwo matsva evarwere vane gomarara. Kana kiriniki miedzo ikaratidza kuti kurapwa kutsva kuri nani pane kwese kurapwa, kurapwa kutsva kunogona kuve kwakajairwa kurapwa. Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki. Mimwe miedzo yekiriniki yakavhurwa chete kune varwere vasina kutanga kurapwa.

Mhando shanu dzekurapwa kwakajairika dzinoshandiswa:

Kurinda kumirira

Kurindira kumirira kuri kunyatsoongorora mamiriro emurwere pasina kupa chero kurapwa kusvikira zviratidzo kana zviratidzo zvaonekwa kana kuchinja. Izvi zvinonziwo kucherechedza. Munguva ino, matambudziko anokonzerwa nechirwere, senge hutachiona, anorapwa.

Radiation Therapy Radiation kurapa chirwere chegomarara chinoshandisa simba rakawanda x-ray kana mamwe marudzi emwaranzi kuuraya maseru ekenza kana kuachengetedza kuti asakure. External radiation therapy inoshandisa muchina uri kunze kwemuviri kutumira radiation kune iyo nzvimbo yemuviri nekenza.

External radiation therapy inoshandiswa kurapa chirwere cheLymphocytic leukemia.

Chemotherapy

Chemotherapy mushonga wekenza unoshandisa mishonga kumisa kukura kwemasero ekenza, kungave nekuuraya maseru kana nekuamisa iwo kubva pakupatsanuka. Kana chemotherapy ikatorwa nemuromo kana kujowa mutsinga kana mhasuru, mishonga inopinda muropa uye inogona kusvika masero emukenza mumuviri wese (systemic chemotherapy). Kana chemotherapy ikaiswa yakanangana necerebrospinal fluid, nhengo, kana muviri mhasuru senge dumbu, kana iwo madhiragi anonyanya kukanganisa cancer maseru munzvimbo idzodzo (remunharaunda chemotherapy). Nzira iyo chemotherapy inopihwa inoenderana nerudzi uye nhanho yekenza iri kurapwa.

Ona Zvinodhaka Zvinotenderwa Zvechirwere cheLymphocytic Leukemia kuti uwane rumwe ruzivo.

Kuvhiya

Splenectomy kuvhiyiwa kubvisa iyo spleen.

Targeted kurapwa

Targeted therapy mhando yekurapa inoshandisa zvinodhaka kana zvimwe zvinhu kuti zvione uye kurwisa chaiwo maseru ekenza pasina kukuvadza zvakajairika maseru. Monoclonal antibody therapy, tyrosine kinase inhibitor therapy, uye BCL2 inhibitor kurapa ndiwo marudzi eanotarisirwa kurapwa anoshandiswa pakurapa kwechirwere cheLymphocytic leukemia.

Tyrosine kinase inhibitor kurapa chirwere chegomarara chinovharira zviratidzo zvinodikanwa kuti mamota akure.

BCL2 inhibitor kurapa mushonga wekenza unovhara protein inonzi BCL2. BCL2 inhibitor kurapa kunogona kuuraya maseru ekenza uye kunogona kuita kuti vawedzere kunetseka kune mimwe mishonga inorwisa cancer.

Ona Zvinodhaka Zvinotenderwa Zvechirwere cheLymphocytic Leukemia kuti uwane rumwe ruzivo.

Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

Ichi chidimbu chikamu chinotsanangura kurapwa kuri kuongororwa mumakiriniki ekuedzwa. Zvinogona kusataura nezveese marapirwo matsva ari kuongororwa. Ruzivo nezve kiriniki miedzo inowanikwa kubva kuNCI webhusaiti.

Chemotherapy ne stem cell yekuisa

Chemotherapy ne stem cell transplant inzira yekupa chemotherapy uye kutsiva masero anogadzira ropa akaparadzwa nekenza kurapwa. Masero emashizha (masero eropa asina kusimba) anobviswa muropa kana mwongo wemapfupa emurwere kana mupi uye anoomeswa nechando. Mushure mokunge chemotherapy yapera, masero akachengetwa anonyungudutswa uye ndokudzoserwa kumurwere kuburikidza nekumukiswa. Aya akadzikiswa maseru emadzinde anokura kuita (uye kudzoreredza) masero eropa emuviri.

Immunotherapy

Immunotherapy kurapwa kunoshandisa immune system yemurwere kurwisa gomarara. Zvinhu zvinogadzirwa nemuviri kana kugadzirwa murabhoritari zvinoshandiswa kusimudzira, kunongedza, kana kudzorera kudzivirira kwemuviri kurwisa kenza. Rudzi rwekurapa kenza urwu rwunonziwo biotherapy kana biologic therapy.

CAR T-cell kurapa rudzi rwe immunotherapy iyo inoshandura yemurwere T masero (rudzi rwe immune immune cell) saka ivo vanozorwisa mamwe mapuroteni ari pamusoro pecancer maseru. T maseru anotorwa kubva kumurwere uye akakosha maakagamuchirwa anowedzerwa kumusoro kwawo murabhoritari. Masero akachinjwa anonzi chimeric antigen receptor (CAR) T masero. Masero eCAR T anokurirwa murabhoritari uye anopiwa murwere nekumukisa. Masero eCAR T anowanda muropa remurwere uye anorwisa maseru egomarara. CAR T-cell kurapa kuri kuongororwa mukurapa kwechirwere cheLymphocytic leukemia.

MOTO T-cell kurapa. Rudzi rwekurapa umo masero eT emurwere (rudzi rwemuviri wemasero emuviri) anochinjwa murabhoritari kuitira kuti vasunge masero egomarara vovauraya. Ropa kubva mutsinga iri muruoko rwemurwere inoyerera nepombi kusvika kumuchina weapheresis (usina kuratidzwa), unobvisa masero eropa machena, kusanganisira maT seli, uye wotumira iro rasara rose ropa kumurwere. Zvino, iyo geni yeakagamuchirwa yakakosha inonzi chimeric antigen receptor (CAR) inoiswa mukati meT maseru murabhoritari. Mamirioni emaCAR T maseru anokurirwa murabhoritari uye ndokuzopihwa kumurwere nekumukisa. Masero eCAR T anokwanisa kusunga kune antigen pane masero ekenza uye nekuvauraya.

Kurapa kwechirwere cheLymphocytic leukemia kunogona kukonzera mhedzisiro.

Kuti uwane ruzivo nezve mhedzisiro inokonzerwa nekurapwa kwegomarara, ona yedu Side Mhedzisiro peji.

Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

Kune vamwe varwere, kutora chikamu mumuedzo wekiriniki inogona kunge iri sarudzo yekurapa yakanyanya kunaka. Kliniki miedzo chikamu chekenza tsvagiridzo. Zvemakiriniki miedzo inoitwa kuti uone kana marapirwo matsva egomarara akachengeteka uye achishanda kana zvirinani pane akajairwa kurapwa.

Mazhinji emazuva ano marapirwo akajairwa ekenza akavakirwa pamavambo emakiriniki ekuedzwa. Varwere vanotora chikamu mukuyedzwa kwekiriniki vanogona kuwana kurapwa kwakaringana kana kuve pakati pevekutanga kurapwa kutsva.

Varwere vanotora chikamu mumiedzo yekiriniki zvakare vanobatsira kugadzirisa marapirwo achaitwa kenza mune ramangwana. Kunyangwe kana miedzo yemakiriniki isinga tangire kumarapirwo matsva anoshanda, anowanzo pindura mibvunzo yakakosha uye anobatsira kufambisira mberi kutsvagurudza.

Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kenza kurapwa.

Mimwe miedzo yekiriniki inosanganisira chete varwere vasati vagamuchira kurapwa. Mimwe miedzo yekuedza kurapwa kwevarwere vane kenza haina kuve nani. Kune mamwezve emakiriniki miedzo inoedza nzira nyowani dzekumisa cancer kubva kudzokororazve (kudzoka) kana kudzikisira mhedzisiro yemakenza kurapwa.

Kuedzwa kwemakiriniki kuri kuitika munzvimbo zhinji dzenyika. Ruzivo nezve kiriniki miedzo inotsigirwa neNCI inogona kuwanikwa paNCI yekiriniki miedzo yekutsvaga peji rewebhu. Kliniki miedzo inotsigirwa nemamwe masangano inogona kuwanikwa pane yeClinicalTrials.gov webhusaiti.

Yekutevera-bvunzo inogona kudikanwa.

Mimwe miedzo yakaitwa kuongorora gomarara kana kutsvaga danho rekenza inogona kudzokororwa. Dzimwe bvunzo dzinodzokororwa kuitira kuti vaone kuti kurapa kuri kushanda sei. Sarudzo nezvekuti uenderere mberi, shandura, kana kumisa kurapwa kunogona kunge kuchibva pamhedzisiro yeiyi bvunzo.

Mimwe bvunzo ichaenderera ichiitwa nguva nenguva mushure mekunge kurapwa kwapera. Mhedzisiro yeiyi bvunzo inogona kuratidza kana mamiriro ako achinja kana kana gomarara radzoka (dzoka). Iyi bvunzo dzimwe nguva inonzi yekuteedzera-bvunzo kana kuongorora-kumusoro.

Kurapa Sarudzo nedanho

Muchikamu chino

• Stage 0 Chisingaperi Lymphocytic Leukemia

• Chikamu I, Chikamu II, Chikamu chechitatu, uye Chikamu IV Chisingaperi Lymphocytic Leukemia

Kuti uwane ruzivo nezve marapirwo akanyorwa pazasi, ona iyo Chikamu Sarudzo Yekutarisa Chikamu.

Stage 0 Chisingaperi Lymphocytic Leukemia

Kurapa kwechitsauko 0 chisingagumi lymphocytic leukemia inowanzo tarisa kumirira.

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Chikamu I, Chikamu II, Chikamu chechitatu, uye Chikamu IV Chisingaperi Lymphocytic Leukemia

Kurapa kwedanho I, danho II, danho III, uye nhanho IV chisingaperi lymphocytic leukemia inogona kusanganisira zvinotevera:

• Kutarisa kumirira kana paine mashoma kana pasina zviratidzo kana zviratidzo.

• Targeted Therapy ine monoclonal antibody, tyrosine kinase inhibitor, kana BCL2 inhibitor.

• Chemotherapy ne1 kana zvimwe zvinodhaka, zvine kana pasina steroids kana monoclonal antibody therapy.

• Low-dose ekunze radiation kurapwa kune nzvimbo dzemuviri uko kenza inowanikwa, senge spleen kana lymph node.

• Kuongororwa kwekiriniki kwechemotherapy uye biologic therapy ine stem cell transplant

• Kuongororwa kwekiriniki kwekurapwa kutsva.

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Kurapa Sarudzo dzeRecurrent kana Refractory Chisingaperi Lymphocytic

Leukemia

Treatment of recurrent or refractory chronic lymphocytic leukemia may include one of the treatment options described above or enrollment in a clinical trial of a new treatment. See the Stage I, Stage II, Stage III, and Stage IV Chronic Lymphocytic Leukemia section for more information.

Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.

To Learn More About Chronic Lymphocytic Leukemia

For more information from the National Cancer Institute about chronic lymphocytic leukemia, see the following:

• Leukemia Home Page

• Drugs Approved for Chronic Lymphocytic Leukemia

• Targeted Cancer Therapies

• Immunotherapy to Treat Cancer

Kuti uwane ruzivo rwekenza uye zvimwe zviwanikwa kubva kuNational Cancer Institute, ona zvinotevera:

• Nezve Kenza

• Stage

• Chemotherapy uye Iwe: Tsigiro Yevanhu Vane Kenza

• Radiation Therapy uye Iwe: Rutsigiro rweVanhu Vane Kenza

• Kurarama neCancer

• Mibvunzo Yekubvunza Wako Chiremba nezveCancer

• Kune Vakapona uye Vanotarisira