Mhando / leukemia / murwere / mukuru-aml-kurapwa-pdq

Vakuru Acute Myeloid Leukemia Kurapa (?) - Patient Shanduro

General Ruzivo nezveVakuru Acute Myeloid Leukemia

PFUNGWA DZINOKOSHA

• Adult acute myeloid leukemia (AML) rudzi rwekenza umo mwongo wemapfupa unogadzira zvisina kujairika myeloblasts (rudzi rwechena ropa masero), masero matsvuku eropa, kana maplatelet.

• Leukemia inogona kukanganisa masero matsvuku eropa, machena masero eropa, uye maplatelet.

• Kune akasiyana madiki madiki e AML.

• Kusvuta, yapfuura chemotherapy kurapwa, uye kuratidzwa kune radiation kunogona kukanganisa njodzi yevakuru AML.

• Zviratidzo nezviratidzo zvevakuru AML zvinosanganisira kupisa muviri, kunzwa kuneta, uye kupwanya kuri nyore kana kubuda ropa.

• Kuyedza kunoongorora ropa nemongo wemapfupa kunoshandiswa kutsvaga (kuwana) uye kuongorora vakuru AML.

• Zvimwe zvinhu zvinokanganisa kufungidzira (mukana wekupora) uye sarudzo dzekurapa.

Adult acute myeloid leukemia (AML) rudzi rwekenza umo mwongo wemapfupa unogadzira zvisina kujairika myeloblasts (rudzi rwechena ropa masero), masero matsvuku eropa, kana maplatelet.

Adult acute myeloid leukemia (AML) igomarara reropa nemapfupa. Rudzi urwu rwegomarara kazhinji runokurumidza kukura kana rukasarapwa. Iyo ndiyo yakajairika mhando yeacute leukemia muvakuru. AML inonziwo acute myelogenous leukemia, acute myeloblastic leukemia, acute granulocytic leukemia, uye acute nonlymphocytic leukemia.

Anatomy yebhonzo. Bhonzo rinoumbwa necompact bone, spongy bone, uye mwongo wefupa. Compact bone rinoumba chikamu chekunze chepfupa. Spongy bone rinowanikwa zvakanyanya kumagumo emabhonzo uye rine mutsvuku. Bhonzo remapfupa rinowanikwa pakati pemapfupa mazhinji uye rine tsinga zhinji dzeropa. Kune mhando mbiri dzemongo wemapfupa: tsvuku uye yero. Mutsvuku mutsvuku une masero eropa anogona kuve masero matsvuku eropa, machena masero eropa, kana maplatelet. Yero mwongo inogadzirwa kazhinji yemafuta.

Leukemia inogona kukanganisa masero matsvuku eropa, machena masero eropa, uye maplatelet.

Kazhinji, mwongo wemapfupa unoita maseru eropa (maseru asina kukura) anova masero eropa akakura nekufamba kwenguva. Sero reropa rinogona kuva myeloid stem cell kana lymphoid stem cell. Lymhoid stem cell rinova jena reropa jena.

Iyo myeloid stem sero inova imwe yemhando nhatu dzemasero eropa akura:

• Masero matsvuku eropa anotakura okisijeni nezvimwe zvinhu kumatishu ese emuviri.

• Masero machena eropa anorwisa hutachiona nezvirwere.

• Maplatelet ayo anogadzira ropa kuwacha kubuda ropa.

Ropa masero kukura. Sero reropa rinopinda nematanho akati wandei kuti riite tsvuku reropa, platelet, kana chena reropa.

MuAML, iyo maseroid masero masero anowanzo kuve mhando yembeu chena yeropa inonzi myeloblasts (kana myeloid blast). Iyo myeloblasts muAML haina kujairika uye haigone kuita machena maseru eropa. Dzimwe nguva muAML, akawandisa masero emadzinde anova masero matsvuku eropa kana maplatelet. Aya maseru eropa asina kujairika, masero matsvuku eropa, kana maplatelet anonziwo maseru eukemia kana kuputika. Masero eLeukemia anogona kuvaka mumongo nemuropa saka pane nzvimbo shoma yemasero machena eropa, masero matsvuku eropa, uye maplatelet. Kana izvi zvikaitika, hutachiona, kupererwa neropa, kana kubuda ropa nyore zvinogona kuitika. Masero eleukemia anogona kupararira kunze kweropa kuenda kune zvimwe zvikamu zvemuviri, kusanganisira iyo yepakati tsinga system (huropi uye musana), ganda, uye matadza.

Iyi pfupiso ndeyevakuru AML. Ona inotevera pfupiso yePDPQ yeruzivo nezve mamwe marudzi eleukemia:

• Zvepwere Acute Myeloid Leukemia / Imwe Myeloid Malignancies Kurapa

• Chisingaperi Myelogenous Leukemia Kurapa

• Vakuru Acute Lymphoblastic Leukemia Kurapa

• Zvepwere Acute Lymphoblastic Leukemia Kurapa

• Chisingaperi Lymphocytic Leukemia Kurapa

• Bvudzi Cell Leukemia Kurapa

Kune akasiyana madiki madiki e AML.

Mazhinji AML subtypes anoenderana nekukura (kuvandudza) masero ekenza panguva yekuongororwa uye kuti akasiyana sei nemasero akajairwa.

Acute promyelocytic leukemia (APL) chidimbu cheAML chinoitika kana zvikamu zvemageneti maviri zvinonamira pamwechete. APL inowanzoitika muvakuru vane zera repakati. Zviratidzo zveAPPL zvinogona kusanganisira zvese kubuda ropa uye kugadzira ropa.

Kusvuta, yapfuura chemotherapy kurapwa, uye kuratidzwa kune radiation kunogona kukanganisa njodzi yevakuru AML.

Chero chipi zvacho chinowedzera njodzi yako yekuwana chirwere chinonzi njodzi chinhu. Kuva nenjodzi hazvireve kuti uchawana gomarara; kusava nenjodzi hazvireve kuti hauzobatwe negomarara. Taura nachiremba wako kana iwe uchifunga kuti ungave uri panjodzi. Zvimwe zvinogona kuisa njodzi kune AML zvinosanganisira zvinotevera:

• Kuva murume.

• Kusvuta, kunyanya mushure memakore makumi matanhatu.

• Kuve nekurapwa ne chemotherapy kana radiation radiation munguva yakapfuura.

• Kuve nekurapwa kwehudiki acute lymphoblastic leukemia (ZVA) munguva yakapfuura.

• Kuburitswa nemwaranzi kubva kubhomba reatomiki kana kune kemikari benzene.

• Kuve nenhoroondo yechirwere cheropa senge myelodysplastic syndrome.

Zviratidzo nezviratidzo zvevakuru AML zvinosanganisira kupisa muviri, kunzwa kuneta, uye kupwanya kuri nyore kana kubuda ropa.

Zviratidzo zvekutanga zve AML zvinogona kunge zvakaita izvo zvinokonzerwa nefuruwenza kana zvimwe zvirwere zvakajairika. Tarisa nachiremba wako kana iwe uine chero chinotevera:

• Kupindwa nechando.

• Kufema kwekufema.

• Kupwanya kuri nyore kana kubuda ropa.

• Petechiae (yakati sandara, inongedzera mavara pasi peganda rinokonzerwa nekubuda ropa).

• Kuneta kana kunzwa kuneta.

• Kurera huremu kana kurasikirwa nechido.

Kuyedza kunoongorora ropa nemongo wemapfupa kunoshandiswa kutsvaga (kuwana) uye kuongorora vakuru AML.

Iyi inotevera bvunzo uye maitiro anogona kushandiswa:

• Kuongorora kwepanyama uye nhoroondo: Kuongororwa kwemuviri kutarisa zviratidzo zvehutano, kusanganisira kuongorora zviratidzo zvehosha, zvakadai semapundu kana chero chinhu chinoratidzika sechisina kujairika. Nhoroondo yemaitiro ehutano hwemurwere uye kurwara kwakapfuura uye kurapwa kuchatorwawo.

• Yakazara kuverenga kweropa (CBC): Maitiro umo muyenzaniso weropa unodhonzwa nekuongororwa zvinotevera:

• Huwandu hwemasero matsvuku eropa, machena masero eropa, uye maplatelet.

• Huwandu hwehemoglobin (protein inotakura oxygen) mumasero matsvuku eropa.

• Chikamu chemuenzaniso chakaumbwa nemasero matsvuku eropa.

Yakazara kuverenga ropa (CBC). Ropa rinounganidzwa nekupinza tsono mutsinga uye richiita kuti ropa riyerere muhubhu. Muenzaniso weropa unotumirwa murabhoritari uye masero matsvuku eropa, masero machena eropa, uye maplatelet anoverengwa. Iyo CBC inoshandiswa kuyedza, kuongorora, uye kuongorora akawanda mamiriro akasiyana.

• Peripheral ropa smear: Maitiro umo muyenzaniso weropa unotariswa nekufema masero, nhamba uye mhando dzemasero machena eropa, huwandu hwemaplatelet, uye shanduko muchimiro chemasero eropa.

• Bone marrow aspiration uye biopsy: Kubviswa kwemongo wefupa, ropa, uye chidimbu chefupa nekuisa tsono isina mhango muhudyu kana pfupa rechipfuva. Nyanzvi yezvirwere anoona pfupa, ropa, uye pfupa pasi pe microscope kutsvaga zviratidzo zvegomarara.

Bone marora chishuwo uye biopsy. Mushure mekunge nzvimbo diki yeganda yave nechiveve, tsono yemongo wemapfupa inoiswa mupfupa rehudyu remurwere. Samples reropa, bhonzo, uye mwongo wemapfupa zvinobviswa kuti zviongororwe pasi pe microscope.

• Kuongorora kweCytogenetic: Kuongororwa kwerabhoritari umo ma chromosomes emaseru mune muyenzaniso weropa kana mongo wemapfupa anoverengwa uye kuongororwa chero shanduko, sekutyorwa, kushaikwa, kurongedzwa patsva, kana mamwe ma chromosomes. Shanduko mune mamwe ma chromosomes inogona kunge iri chiratidzo checancer. Kuongorora kweCytogenetic kunoshandiswa kubatsira kuongorora cancer, kuronga kurapwa, kana kuona kuti kurapa kuri kushanda sei. Mimwe bvunzo, senge fluorescence in situ kusanganiswa (FISH), inogona zvakare kuitwa kutsvaga kumwe kuchinjika mumakromosomes.

• Immunophenotyping: Kuongororwa kwerabhoritari inoshandisa masoja ekudzivirira kenza maseru zvichibva pamhando dzemaantigen kana mamaki ari pamusoro pemasero. Iyi bvunzo inoshandiswa kubatsira kuongorora chaiwo marudzi eleukemia. Semuenzaniso, cytochemistry yekudzidza inogona kuyedza masero mune imwe sosi yetishu uchishandisa makemikari (madhayi) kutsvaga dzimwe shanduko mune iyi sampuro. Kemikari inogona kukonzera shanduko yemuvara mune imwe mhando yeeleukemia cell asi kwete mune imwe mhando yeleukemia cell.

• Reverse transcript- polymerase chain reaction test (RT – PCR): Kuongororwa kwerabhoritari umo huwandu hwechibereko chinonzi mRNA chakagadzirwa neimwe geni chinoyerwa. Enzyme inonzi reverse transcriptase inoshandiswa kushandura chidimbu cheRNA kuita chidimbu cheDNA, icho chinogona kukwidziridzwa (chakaitwa muzvizhinji) neimwe enzyme inonzi DNA polymerase. Akawedzeredzwa maDNA makopi anobatsira kutaurira kana chaiyo mRNA iri kugadzirwa negene. RT-PCR inogona kushandiswa kuongorora kumisikidza kwemamwe majeni anogona kuratidza kuvapo kwemasero ekenza. Iyi bvunzo inogona kushandiswa kutsvaga kumwe kuchinjika mugene kana chromosome, iyo inogona kubatsira kuongorora kenza. Iyi bvunzo inoshandiswa kuongorora mamwe marudzi eAML anosanganisira acute promyelocytic leukemia (APL).

Zvimwe zvinhu zvinokanganisa kufungidzira (mukana wekupora) uye sarudzo dzekurapa.

Kufungidzira (mukana wekupora) uye sarudzo dzekurapa dzinoenderana ne:

• Zera remurwere.

• Chidimbu cheAML.

• Kunyangwe murwere akagamuchira chemotherapy munguva yakapfuura yekurapa imwe cancer.

• Kunyangwe paine nhoroondo yehuropa kusagadzikana senge myelodysplastic syndrome.

• Kunyangwe iyo cancer yakapararira kune yepakati tsinga system.

• Kunyangwe kenza yakamborapwa kare kana kudzokazve (dzoka).

Izvo zvakakosha kuti acute leukemia inorapwa ipapo.

Matanho eVakuru Acute Myeloid Leukemia

PFUNGWA DZINOKOSHA

• Pane imwe nguva munhu akura kwazvo myeloid leukemia (AML) yaonekwa, kuongororwa kunoitwa kuti uone kana gomarara rapararira kune dzimwe nhengo dzemuviri.

• Iko hakuna standard standard staging system yevakuru AML.

Pane imwe nguva munhu akura kwazvo myeloid leukemia (AML) yaonekwa, kuongororwa kunoitwa kuti uone kana gomarara rapararira kune dzimwe nhengo dzemuviri.

Iko kukura kana kupararira kwegomarara kunowanzo rondedzerwa sematanho. Mune munhu mukuru acute myeloid leukemia (AML), iyo subtype yeAML uye kana iyo leukemia yapararira kunze kweropa nemongo wemapfupa zvinoshandiswa pachinhanho chekuronga kurapwa. Iyi inotevera bvunzo uye maitiro anogona kushandiswa kuona kana leukemia yapararira:

• Lumbar puncture: Maitiro anoshandiswa kuunganidza sampu yecebrospinal fluid (CSF) kubva pamutsipa wepelinha. Izvi zvinoitwa nekuisa tsono pakati pemabhonzo maviri mumuzongoza nekupinda muCSF yakakomberedza musana uye kubvisa sampu yemvura. Muenzaniso weCSF unotariswa pasi pe microscope yezviratidzo zvekuti masero erukemia apararira kuuropi uye musana. Maitiro aya anonzi zvakare LP kana musana tap.

Lumbar kubaya. Murwere akarara panzvimbo yakamonana patafura. Mushure mekunge diki nzvimbo kumucheto kumashure yave chiveve, tsono yemusana (tsono refu, nhete) inoiswa muchikamu chezasi chepamuviri mbichana kubvisa cerebrospinal fluid (CSF, inoratidzwa mublue). Mvura yacho inogona kutumirwa kurabhoritari kunoongororwa.

• CT scan (CAT scan): Maitiro anoita akateedzana emifananidzo yakajeka yedumbu, inotorwa kubva kumakona akasiyana. Mifananidzo yacho inogadzirwa nekombuta yakabatana neiyo x-ray muchina. Dhayi inogona kuiswa jekiseni kana kumedzwa kubatsira nhengo kana zvinyama kuratidza zvakajeka. Iyi nzira inonziwo computed tomography, computerized tomography, kana komputa axial tomography.

Iko hakuna standard standard staging system yevakuru AML.

Chirwere chinotsanangurwa sechisina kurapwa, mukuregererwa, kana kudzoka.

Asina kurapwa murume mukuru AML

Mumunhu mukuru asina kurapwa, AML, chirwere ichi chichangobva kuongororwa. Haina kurapwa kunze kwekubvisa zviratidzo nezviratidzo zvakaita sefivha, kubuda ropa, kana kurwadziwa, uye zvinotevera ndezvechokwadi:

• Iyo yakazara yakazara kuverenga haina kujairika.

• Angangoita makumi maviri muzana emasero ari mumongo wemabhonzo anoputika (masero eleukemia).

• Pane zviratidzo kana zviratidzo zveleukemia.

Mukuru AML mukuregererwa

Mune munhu mukuru AML mukuregererwa, chirwere chakarapwa uye zvinotevera ndezvechokwadi:

• Kuwanda kweropa kwakazara kunoitika.

• Asingasviki mashanu muzana emasero ari mumongo wemabhonzo anoputika (masero eleukemia).

• Iko hakuna zviratidzo kana zviratidzo zveleukemia muuropi uye musana wechipfuva kana kumwe kunhu mumuviri.

Kudzokorora Munhu Mukuru AML

Yakazara AML kenza yakadzokazve (kudzoka) mushure mekurapwa. AML inogona kudzoka muropa kana pfupa remongo.

Kurapa Sarudzo Kuongorora

PFUNGWA DZINOKOSHA

• Kune akasiyana marudzi ekurapa kwevarwere vane vakuru acute myeloid leukemia.
• Kurapa kwevakuru AML kazhinji kune zvikamu zviviri.
• Mhando ina dzekurapa kwakajairika dzinoshandiswa:

• Chemotherapy

• Radiation kurapa

• Chemotherapy ne stem cell yekuisa

• Imwe mishonga yekurapa

• Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

• Targeted kurapwa

• Kurapa kwevanhu vakuru myeloid leukemia kunogona kukonzera mhedzisiro.

• Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

• Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kenza kurapwa.

• Yekutevera-bvunzo inogona kudikanwa.

Kune akasiyana marudzi ekurapa kwevarwere vane vakuru acute myeloid leukemia.

Mhando dzakasiyana dzekurapa dzinowanikwa kune varwere vane vakuru acute myeloid leukemia (AML). Mamwe marapirwo akajairwa (iko kurapwa kwazvino kwashandiswa), uye kumwe kuedzwa mumakiriniki ekuedzwa A kurapwa kiriniki kuyedzwa chidzidzo chekutsvaga chakaitirwa kubatsira kuvandudza marapirwo azvino kana kuwana ruzivo marapirwo matsva evarwere vane gomarara. Kana kiriniki miedzo ikaratidza kuti kurapwa kutsva kuri nani pane kwese kurapwa, kurapwa kutsva kunogona kuve kwakajairwa kurapwa. Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki. Mimwe miedzo yekiriniki yakavhurwa chete kune varwere vasina kutanga kurapwa.

Kurapa kwevakuru AML kazhinji kune zvikamu zviviri.

Iwo maviri ekurapa zvikamu zvevakuru AML ndeaya:

• Kuregererwa induction Therapy: Ichi chikamu chekutanga chekurapa. Chinangwa ndechekuuraya masero eleukemia muropa nemongo wemapfupa. Izvi zvinoisa leukemia mukuregererwa.

• Post-remission therapy: Ichi chikamu chechipiri chekurapa. Inotanga mushure mekunge leukemia iri mukuregererwa. Chinangwa chekurapa-kuregererwa kurapa kuuraya chero maseru eleukemia akasara anogona kunge asiri kushanda asi anogona kutanga kudzoka uye kukonzera kudzokazve. Ichi chikamu chinonzi zvakare kuregererwa kuenderera mberi kurapwa.

Mhando ina dzekurapa kwakajairika dzinoshandiswa:

Chemotherapy

Chemotherapy mushonga wekenza unoshandisa mishonga kumisa kukura kwemasero ekenza, kungave nekuuraya maseru kana nekuamisa iwo kubva pakupatsanuka. Kana chemotherapy ikatorwa nemuromo kana kujowa mutsinga kana mhasuru, mishonga inopinda muropa uye inogona kusvika masero emukenza mumuviri wese (systemic chemotherapy). Kana chemotherapy ikaiswa yakanangana necerebrospinal fluid (intrathecal chemotherapy), nhengo, kana dumbu remuviri senge dumbu, mishonga inonyanya kukanganisa maseru ekenza munzvimbo idzodzo (chemotherapy yedunhu). Intrathecal chemotherapy inogona kushandiswa kurapa vanhu vakuru AML yakapararira kuuropi uye musana. Kusanganiswa chemotherapy kurapwa kunoshandisa anopfuura imwe anticancer mushonga.

Nzira iyo chemotherapy inopihwa inoenderana ne subtype ye AML iri kurapwa uye kana masero eleukemia apararira kuuropi uye musana.

Intrathecal chemotherapy. Anticancer zvinodhaka zvinopinda mukati meiyo intrathecal nzvimbo, inova iyo nzvimbo inobata iyo cerebrospinal fluid (CSF, inoratidzwa mublue). Pane nzira mbiri dzakasiyana dzekuita izvi. Imwe nzira, inoratidzwa muchikamu chepamusoro chemufananidzo, kuisa majekiseni mumugodhi weOmaya (mudziyo wakaita sedome wakaiswa pasi peganda panguva yekuvhiyiwa; inobata mishonga painenge ichiyerera nepombi diki ichienda muuropi ). Imwe nzira, inoratidzwa muchikamu chepazasi chemufananidzo, kupinza mishonga yakananga muCSF muchikamu chepazasi chechipenga chemusana, mushure mekunge nzvimbo diki kumusana wezasi yave nechiveve.

Ona Zvinodhaka Zvinotenderwa kune Acute Myeloid Leukemia kune rumwe ruzivo.

Radiation kurapa

Radiation kurapa kurapwa kenza iyo inoshandisa yakakwira-simba x-rays kana mamwe marudzi e radiation kuuraya cancer maseru kana kuachengeta iwo kuti asakure. Kune mhando mbiri dze radiation radiation:

• External radiation therapy inoshandisa muchina uri kunze kwemuviri kutumira radiation kune kenza.

• Yemukati radiation kurapwa kunoshandisa radioactive chinhu chakavharirwa mune tsono, mhodzi, waya, kana makateti anoiswa akananga mukati kana padyo nekenza.

Maitiro ekurapwa nemwaranzi anopiwa zvinoenderana nerudzi rwegomarara riri kurapwa uye kuti maseru erukemia apararira kuuropi nemuzongoza. External radiation therapy inoshandiswa kurapa vakuru AML.

Chemotherapy ne stem cell yekuisa

Chemotherapy inopihwa kuuraya cancer maseru. Masero ane hutano, kusanganisira masero anogadzira ropa, anoparadzwa nekenza kurapwa. Stem cell transplant kurapwa kwekutsiva maseru anogadzira ropa. Masero emashizha (masero eropa asina kusimba) anobviswa muropa kana mwongo wemapfupa emurwere kana mupi uye anoomeswa nechando. Mushure mekunge murwere apedza chemotherapy, maseru akachengetwa anonyungudutswa uye ndokudzoserwa kumurwere kuburikidza nekumukiswa. Aya akadzikiswa maseru emadzinde anokura kuita (uye kudzorera) masero eropa emuviri.

Stem cell kuisirwa. (Nhanho 1): Ropa rinotorwa kubva mutsinga iri muruoko rweanopa. Murwere kana mumwe munhu angave ari mupi. Ropa rinoyerera nemuchina unobvisa masero emadzinde. Ipapo iro ropa rinodzoserwa kune anenge apa kuburikidza netsinga iri mune rumwe ruoko. (Nhanho 2): Murwere anogamuchira chemotherapy kuuraya masero anogadzira ropa. Murwere anogona kupihwa radiation radiation (isina kuratidzwa). (Nhanho 3): Murwere anogamuchira masero emadzinde kuburikidza nekateti yakaiswa mumudziyo weropa muchipfuva.

Imwe mishonga yekurapa

Arsenic trioxide uye yese-trans retinoic acid (ATRA) mishonga inorwisa kenza iyo inouraya maseru eecemia, inomisa maseru eukemia kubva pakupatsanuka, kana kubatsira masero eleukemia akure kuita machena masero eropa. Iyi mishonga inoshandiswa pakurapa chikamu cheAML chinonzi acute promyelocytic leukemia.

Ona Zvinodhaka Zvinotenderwa kune Acute Myeloid Leukemia kune rumwe ruzivo.

Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

Ichi chidimbu chikamu chinotsanangura kurapwa kuri kuongororwa mumakiriniki ekuedzwa. Zvinogona kusataura nezveese marapirwo matsva ari kuongororwa. Ruzivo nezve kiriniki miedzo inowanikwa kubva kuNCI webhusaiti.

Targeted kurapwa

Targeted therapy mhando yekurapa inoshandisa zvinodhaka kana zvimwe zvinhu kuti zvione uye kurwisa chaiwo maseru ekenza pasina kukuvadza zvakajairika maseru. Monoclonal antibody therapy ndeimwe yemhando yekurapa kwakanangidzirwa kuri kudzidziswa mukurapa kwevakuru AML.

Monoclonal antibody therapy ndeye kenza kurapa iyo inoshandisa antibodies inogadzirwa murabhoritari kubva kune imwechete mhando ye immune immune cell. Aya ma antibodies anokwanisa kuona zvinhu pane cancer cancer kana zvakajairika zvinhu zvinogona kubatsira gomarara maseru kukura. Masoja ekudzivirira chirwere anonamira pazvinhu uye anouraya maseru egomarara, anovharira kukura kwawo, kana kuti aachengetedze kubva pakupararira. Monoclonal antibodies inopihwa nekumisirwa. Inogona kushandiswa yoga kana kutakura zvinodhaka, chepfu, kana zvinhu zvine radioactive zvakanangana nemasero ekenza.

Kurapa kwevanhu vakuru myeloid leukemia kunogona kukonzera mhedzisiro.

Kuti uwane ruzivo nezve mhedzisiro inokonzerwa nekurapwa kwegomarara, ona yedu Side Mhedzisiro peji.

Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

Kune vamwe varwere, kutora chikamu mumuedzo wekiriniki inogona kunge iri sarudzo yekurapa yakanyanya kunaka. Kliniki miedzo chikamu chekenza tsvagiridzo. Zvemakiriniki miedzo inoitwa kuti uone kana marapirwo matsva egomarara akachengeteka uye achishanda kana zvirinani pane akajairwa kurapwa.

Mazhinji emazuva ano marapirwo akajairwa ekenza akavakirwa pamavambo emakiriniki ekuedzwa. Varwere vanotora chikamu mukuyedzwa kwekiriniki vanogona kuwana kurapwa kwakaringana kana kuve pakati pevekutanga kurapwa kutsva.

Varwere vanotora chikamu mumiedzo yekiriniki zvakare vanobatsira kugadzirisa marapirwo achaitwa kenza mune ramangwana. Kunyangwe kana miedzo yemakiriniki isinga tangire kumarapirwo matsva anoshanda, anowanzo pindura mibvunzo yakakosha uye anobatsira kufambisira mberi kutsvagurudza.

Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kenza kurapwa.

Mimwe miedzo yekiriniki inosanganisira chete varwere vasati vagamuchira kurapwa. Mimwe miedzo yekuedza kurapwa kwevarwere vane kenza haina kuve nani. Kune mamwezve emakiriniki miedzo inoedza nzira nyowani dzekumisa cancer kubva kudzokororazve (kudzoka) kana kudzikisira mhedzisiro yemakenza kurapwa.

Kuedzwa kwemakiriniki kuri kuitika munzvimbo zhinji dzenyika. Ruzivo nezve kiriniki miedzo inotsigirwa neNCI inogona kuwanikwa paNCI yekiriniki miedzo yekutsvaga peji rewebhu. Kliniki miedzo inotsigirwa nemamwe masangano inogona kuwanikwa pane yeClinicalTrials.gov webhusaiti.

Yekutevera-bvunzo inogona kudikanwa.

Mimwe miedzo yakaitwa kuongorora gomarara kana kutsvaga danho rekenza inogona kudzokororwa. Dzimwe bvunzo dzinodzokororwa kuitira kuti vaone kuti kurapa kuri kushanda sei. Sarudzo nezvekuti uenderere mberi, shandura, kana kumisa kurapwa kunogona kunge kuchibva pamhedzisiro yeiyi bvunzo.

Mimwe bvunzo ichaenderera ichiitwa nguva nenguva mushure mekunge kurapwa kwapera. Mhedzisiro yeiyi bvunzo inogona kuratidza kana mamiriro ako achinja kana kana gomarara radzoka (dzoka). Iyi bvunzo dzimwe nguva inonzi yekuteedzera-bvunzo kana kuongorora-kumusoro.

Kurapa Sarudzo dzeVakuru Acute Myeloid Leukemia

Muchikamu chino

• Asina kurapwa Munhu Mukuru Acute Myeloid Leukemia

• Vakuru Acute Myeloid Leukemia Mukuregererwa

• Kudzokororwa Kwevakuru Kwakanyanya Myeloid Leukemia

Kuti uwane ruzivo nezve marapirwo akanyorwa pazasi, ona iyo Chikamu Sarudzo Yekutarisa Chikamu.

Asina kurapwa Munhu Mukuru Acute Myeloid Leukemia

Kurapa kwakasarudzika kweasina kurapwa munhu akanyanya myeloid leukemia (AML) panguva yekuregererwa induction chikamu kunoenderana ne subtype ye AML uye inogona kusanganisira zvinotevera:

• Kusanganiswa chemotherapy.

• Yepamusoro-dose mubatanidzwa chemotherapy.

• Yakadzika-dose chemotherapy.

• Intrathecal chemotherapy.

• Yese-trans retinoic acid (ATRA) pamwe ne arsenic trioxide yekurapa kweacute promyelocytic leukemia (APL).

• ATRA inosanganisa chemotherapy inoteverwa ne arsenic trioxide yekurapa kweAPP.

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Vakuru Acute Myeloid Leukemia Mukuregererwa

Kurapa kwevakuru AML panguva yekuregererwa chikamu kunoenderana nekamhando ke AML uye kunogona kusanganisira zvinotevera:

• Kusanganiswa chemotherapy.

• Yakakwira-dose chemotherapy, iine kana isina radiation radiation, uye stem masero ekuisa uchishandisa iwo maseru emurwere.

• Yakakwira-dose chemotherapy uye stem cell yekuisa uchishandisa vanopa masero masero.

• Kuongororwa kwekiriniki kwe arsenic trioxide.

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Kudzokororwa Kwevakuru Kwakanyanya Myeloid Leukemia

Iko hakuna kwakajairika kurapwa kweanodzokororwa munhu mukuru AML. Kurapa kunoenderana ne subtype ye AML uye inogona kusanganisira zvinotevera:

• Kusanganiswa chemotherapy.

• Targeted Therapy ine monoclonal antibodies.

• Stem cell transplant uchishandisa masero emurwere.

• Arsenic trioxide kurapa.

• Kuongororwa kwekiriniki kwe arsenic trioxide therapy inoteverwa ne stem cell transplant.

Shandisa yedu kiriniki yekuyedza kutsvaga kutsvaga NCI-yakatsigirwa kenza kiriniki miedzo iri kugamuchira varwere. Unogona kutsvaga miedzo zvichibva parudzi rwecancer, zera remurwere, uye iko kunoitwa miyedzo. Ruzhinji ruzivo nezve zvekuedzwa zvekiriniki zvakare zviripo.

Kuti Udzidze Zvakawanda Pamusoro peVakuru Acute Myeloid Leukemia Cancer

Kuti uwane rumwe ruzivo kubva kuNational Cancer Institute nezve munhu mukuru acry myeloid leukemia, ona zvinotevera:

• Leukemia Peji Peji

• Zvinodhaka Zvinotenderwa kune Acute Myeloid Leukemia

• Ropa-Richigadzira Stem Cell Inoshandura

• Targeted Cancer Therapies

Kuti uwane ruzivo rwekenza uye zvimwe zviwanikwa kubva kuNational Cancer Institute, ona zvinotevera:

• Nezve Kenza

• Stage

• Chemotherapy uye Iwe: Tsigiro Yevanhu Vane Kenza

• Radiation Therapy uye Iwe: Rutsigiro rweVanhu Vane Kenza

• Kurarama neCancer

• Mibvunzo Yekubvunza Wako Chiremba nezveCancer

• Kune Vakapona uye Vanotarisira