Mhando / hudiki-kanzira / hp / isina kujairika-kanzira-yehucheche-pdq
Kazhinji Kanzera Yekurapa Kwevacheche
Ruzivo Ruzhinji Nezve Rare Cancers yeUdiki
Muchikamu chino
- Nhanganyaya
Nhanganyaya
Kenza muvana nevechiri kuyaruka isingawanzoitika, kunyange hazvo chiitiko chekenza yehucheche ichive ichiwedzera zvishoma nezvishoma kubvira 1975. [1] Kuendeswa kunzvimbo dzekurapa dzine zvikwata zvakasiyana-siyana zvevacancer vane ruzivo rwekurapa kanzira dzinoitika muhucheche nekuyaruka dzinofanirwa kutariswa kuvana nevechiri kuyaruka vane gomarara. Iyi nzira yechikwata chakasiyana siyana inosanganisira hunyanzvi hwechiremba wekutanga wekuvhiya, vana chiremba vanovhiya, radiation oncologists, vana vechiremba oncologists / hematologists, nyanzvi dzekuvandudza, vanamukoti vanachiremba, vashandi vezvemagariro, nevamwe kuona kuti vana vanowana kurapwa, kutsigirwa, uye kugadziridzwa izvo ichawana hupenyu hwakakwana uye hupenyu hwehupenyu.
Nongedzo yenzvimbo dzekenza dzevana uye nebasa ravo pakurapa kwevarwere vegomarara dzakatsanangurwa neAmerican Academy yePediatrics. [2] Panzvimbo idzi dzegomarara rezvevana, zviedzo zvemakiriniki zvinowanikwa kune akawanda marudzi ekenza anowanikwa muvana nevechiri kuyaruka, uye mukana wekupinda mumiedzo iyi unopihwa kune vazhinji varwere nemhuri dzavo. Zvemakiriniki miedzo yevana nevechiri kuyaruka vanoonekwa vaine gomarara inowanzo gadzirirwa kuenzanisa inogona kuve nani kurapa nechirapa icho parizvino chinogamuchirwa seyakajairwa. Mazhinji ebudiriro akaitwa mukutsvaga kurapwa kwekurapa kenza dzevacheche kwakawanikwa kuburikidza nemakiriniki ekuedzwa. Ruzivo nezve inoenderera kiriniki miedzo inowanikwa kubva kuNCI webhusaiti.
Kunatsiridzwa kunatsurudzwa mukupona kwakawanikwa kune vana nevechiri kuyaruka vane gomarara. Pakati pa1975 na2010, kufa kwekenza pahucheche kwakaderera nezvikamu zvinodarika makumi mashanu muzana. [3] Vanopona nekenza yehucheche nevechiri kuyaruka vanoda kuongororwa padyo nekuti kenza yekurapa mhedzisiro inogona kuramba kana kukura mwedzi kana makore mushure mekurapwa. (Tarisa pfupiso yePDPQ nezveMagumo Ekurapa kweKenza Yevacheche kune rumwe ruzivo nezve chiitiko, mhando, uye kuongorora kweanononoka mhedzisiro muhucheche nevechiri kuyaruka vapona nekenza.)
Gomarara rehucheche chirwere chisingawanzoitika, iine dzinosvika zviuru gumi nezvishanu zvinoonekwa gore rega rega muUnited States muvanhu vari pasi pemakore makumi maviri. [4] Iyo US Rare Zvirwere Mutemo wa2002 inotsanangura chisingawanzo chirwere seicho chinobata vanhu vadiki pane vanhu zviuru mazana maviri. Naizvozvo, kenza dzese dzevana dzinoonekwa sedzisiri nyore.
Kudomwa kwebundu risingawanzo hakusi yunifomu pakati pemapoka evana uye evakuru. Makura akura asingawanzo anotsanangurwa seaya ane chiitiko chegore negore cheashoma pamatanhatu emakesi pavanhu zviuru zana, uye vanofungidzirwa kuverengera kusvika makumi maviri nezvina muzana emakenza ese akawanikwa muEuropean Union uye nezve 20% yekenza dzese dzinowanikwa muUnited States. . [5,6] Zvakare, kudomwa kwechirwere chisina kujairika kwevana hachina kufanana pakati pemapoka epasi rese, seinotevera:
- Chirongwa chekudyidzana kweItaly pamamota asina kujairika evana (Tumori Rari muEta Pediatrica [TREP]) inotsanangura chirwere chisina kujairika chevana sechimwe chine zviitiko zvisingasviki zviviri pamamiriyoni emamiriyoni evagari pagore uye hachisanganiswi mune mamwe makiriniki ekuedzwa. [7 ]
- Bhuku revana reOncology (COG) rakasarudza kutsanangura kenza dzevana dzisina kujairika seidzo dzakanyorwa muInternational Classification yeChidiki Cancer subgroup XI, inosanganisira cancer yegomarara, melanoma uye nonmelanoma kanzira yeganda, uye marudzi mazhinji ecarcinoma (semuenzaniso, adrenocortical carcinoma, nasopharyngeal carcinoma, uye yakawanda-yerudzi rwema carcinomas senge kenza yemazamu, gomarara rekenza, nezvimwewo.] [8] Aya madhisheni anoverengera angangoita 4% yekenza yakawanikwa muvana vane makore 0 kusvika pamakore gumi nemana, zvichienzaniswa ne20% yekenza yakawanikwa muvachiri kuyaruka vane makore gumi nemashanu kusvika pamakore gumi nemapfumbamwe (tarisa paMifananidzo 1 ne2). [9]
Makenza mazhinji mukati meboka reXI anogona kunge ari maranoma kana gomarara rekenza, nechikamu chinosara chegomarara remhando yekenza XI inongoita 1.3% chete yegomarara muvana vane makore 0 kusvika 14 makore uye 5.3% yekenza mune vechidiki vane makore gumi nemashanu kusvika 19 makore.
Aya macancer asina kujairika ari kunetsa kudzidza nekuti nekuda kwehuwandu hwevarwere vane chero hutachiona, hukuru hwekenza dzisingawanzo muhuwandu hwevechiri kuyaruka, uye kushomeka kwemakiriniki miedzo kune vachiri kuyaruka vane kenza dzisingawanzo senge melanoma.
Vamwe vaongorori vakashandisa dhatabhesi hombe, senge Surveillance, Epidemiology, uye End Mhedzisiro (SEER) uye National Cancer Database, kuwana ruzivo rwakawanda mune aya asinganzwisisike cancer. Nekudaro, izvi zvidzidzo zve database zvine mashoma. Zvirongwa zvakati kuti zviongorore kenza zvevana zvisingawanzoitika zvakagadzirwa neCOG uye mamwe mapoka epasirese, kusanganisira iyo International Society yePediatric Oncology (Société Internationale D'Oncologie Pédiatrique [SIOP]). Iyo Gesellschaft für Pädiatrische Onkologie und Hämatologie (GPOH) isingawanzo bundu chirongwa yakatangwa kuGerman muna 2006. [10] Iyo TREP yakatangwa muna 2000, [7] uye chiPolish Pediatric Rare Tumor Study Group chakatangwa muna 2002. [11] MuEurope, iro risinganzwisisike bundu rinodzidza mapoka kubva kuFrance, Germany, Italy, Poland uye United Kingdom yakabatana muEuropean Cooperative Study Group paPediatric Rare Tumors (EXPeRT), ichitarisa kubatana kwepasi rose uye kuongororwa kweasingawanzo mamota masosi. [12] Mukati meCOG, kuyedza kwakanangana nekuwedzera kuwedzerwa kweCOG kunyoresa (Project Yese Mwana) uye zvimisikidzo zvemabhengi emota, kuvandudza ruoko-rwemakiriniki miedzo, uye kuwedzera kubatana pamwe nemiedzo yeboka revakuru. [13] Zvinoitwa pamwe nematambudziko echirongwa ichi zvakatsanangurwa zvizere. [8,14] uye kuwedzera kubatana pamwe nemiedzo yeboka revakuru. [13] Zvinoitwa pamwe nematambudziko echirongwa ichi zvakatsanangurwa zvizere. [8,14] uye kuwedzera kubatana pamwe nemiedzo yeboka revakuru. [13] Zvinoitwa pamwe nematambudziko echirongwa ichi zvakatsanangurwa zvizere. [8,14]
Mamota akanyorwa muchidimbu ichi akasiyana kwazvo; iwo akarongedzwa mukuburuka kwemaatomic odhi, kubva kune zvisingawanzo mamota emusoro nemutsipa kusvika kushoma matumhu eurrogenital turakiti uye ganda. Ese aya cancer anoshomeka zvakakwana zvekuti zvipatara zvevana zvakawanda zvinogona kuona zvishoma pane mashoma ehumwe histologies mumakore akati wandei. Iyo yakawanda yeiyo histologies yakanyorwa pano inoitika kazhinji muvanhu vakuru. Ruzivo nezve aya mamota runogona kuwanikwawo mumanyuko akakodzera kune vanhu vakuru vane gomarara.
Bvumira mhinduro auto-Refresher