Types/brain/patient/child-glioma-treatment-pdq

Yevacheche Brain Stem Glioma Kurapa (®) -Patient Shanduro

Zveruzhinji Ruzivo Nezve Hwana hweBongo Stem Glioma

PFUNGWA DZINOKOSHA

• Hwecheche huropi hunodzika glioma chirwere umo benign (noncancer) kana yakaipa (gomarara) maseru anoumba mumatumbu ehuropi.

• Kune maviri marudzi ehuropi stem gliomas muvana.

• Chikonzero chemazhinji mamota ehuropi hachizivikanwe.

• Zviratidzo nezviratidzo zvehuropi zvinomira glioma hazvina kufanana mumwana wese.

• Kuyedza kunoongorora huropi kunoshandiswa kuona (tsvaga) hudiki huropi hunodzika glioma.

• Biopsy inogona kuitwa kuti uongorore mamwe marudzi ehuropi stem glioma.

• Zvimwe zvinhu zvinokanganisa kufungidzira (mukana wekupora).

Hwecheche huropi hunodzika glioma chirwere umo benign (noncancer) kana yakaipa (gomarara) maseru anoumba mumatumbu ehuropi.

Gliomas mamota akaumbwa kubva kune glial maseru. Glial masero ari muuropi anobata maseru etsinga munzvimbo, anounza chikafu neoksijeni kumasero etsinga, uye anobatsira kuchengetedza maseru etsinga kubva kuzvirwere, senge hutachiona. Muuropi dzinodzika glioma, iwo maseru e glial ari mudonhe rehuropi anokanganiswa.

Iyo uropi hunde inoumbwa neiyo midbrain, pons, uye medulla. Icho chikamu chepasi chehuropi uye chinobatana netambo yemusana, pamusoro pekuseri kwemutsipa chete. Uropi hunodzora mabasa akakosha senge kufema, kurova kwemoyo, uye BP, uye tsinga nemhasuru zvinoshandiswa mukuona, kunzwa, kufamba, kutaura, uye kudya.

Mazhinji huropi hwehuropi hunodzora magliomas akapararira mukati mepo pontine gliomas (DIPG), ayo anoumba mumaponi. Focal gliomas fomu mune zvimwe zvikamu zvehuropi stem.

Anatomy yehuropi. Iyo supratentorial nzvimbo (iyo yekumusoro chikamu cheuropi) ine iyo cerebrum, lateral ventricle uye yechitatu ventricle (ine cerebrospinal fluid inoratidzwa mublue), choroid plexus, pineal gland, hypothalamus, pituitary gland, uye optic nerve. Iyo posterior fossa / infratentorial nzvimbo (yepazasi kumashure chikamu cheuropi) ine cerebellum, tectum, yechina ventricle, uye brain stem (midbrain, pons, uye medulla). Iyo tendeoriamu inoparadzanisa supratentorium kubva kune infratentorium (kurudyi pani). Dehenya uye meninges zvinodzivirira uropi uye musana (kuruboshwe pani).

Mamota ehuropi ndiwo wechipiri unowanzozivikanwa kenza muvana.

Iyi pfupiso iri pamusoro pekurapwa kwemamota ekutanga ehuropi (mamota anotanga muuropi). Kurapa kwemastastatic brain tumors, ayo ari mamota akaumbwa nekenza maseru ayo anotanga mune mamwe mativi emuviri uye achipararira kuuropi, haina kukurukurwa muchidimbu ichi.

Mamota ehuropi anogona kuitika mune vese vana nevakuru; zvisinei, kurapwa kwevana kunogona kuve kwakasiyana pane kurapwa kwevakuru. Kuti uwane ruzivo nezve kurapwa kwehuropi tumota muvakuru, ona iyo pfupiso Adult Central Nervous System Tumors Treatment.

Kune maviri marudzi ehuropi stem gliomas muvana.

Kunyangwe hazvo DIPG uye yakatarisana nehuropi inokonzeresa glioma fomu mune imwecheteyo sero, vanoita zvakasiyana:

• DIPG . DIPG ibundu rinokurumidza kukura iro rinowanikwa mumaponi. DIPG yakaoma kurapa uye ine fungidziro yakaipa (mukana wekupora) nekuda kweinotevera:

• Haisi bundu rakanyatso tsanangurwa uye rinopararira pakati pemasero ane hutano muhunde hwehuropi.

• Mabasa akakosha, akadai sekufema uye kurova kwemoyo, anogona kukanganiswa.

• Focal uropi hunomira glioma. A focal glioma ibundu rinokura zvishoma-shoma rinoita kunze kwemaponi uye munzvimbo imwechete yehuropi. Zviri nyore kurapa uye zvine fungidziro iri nani pane DIPG.

Chikonzero chemazhinji mamota ehuropi hachizivikanwe.

Chero chipi zvacho chinowedzera njodzi yako yekuwana chirwere chinonzi njodzi chinhu. Kuva nenjodzi hazvireve kuti uchawana gomarara; kusava nenjodzi hazvireve kuti hauzobatwe negomarara. Taura nachiremba wemwana wako kana iwe uchifunga kuti mwana wako angave ari panjodzi. Zvimwe zvinogona kuisa njodzi kuhuropi stem glioma zvinosanganisira:

• Kuve nehumwe hutachiona kusagadzikana, senge neurofibromatosis mhando 1 (NF1).

Zviratidzo nezviratidzo zvehuropi zvinomira glioma hazvina kufanana mumwana wese.

Zviratidzo nezviratidzo zvinoenderana nezvinotevera:

• Ikoko bundu rinoumba muuropi.

• Hukuru hwebundu uye kana rapararira munzvimbo dzese dzehuropi.

• Kurumidza sei bundu kukura.

• Zera remwana uye nhanho yekukura.

Zviratidzo nezviratidzo zvinogona kukonzerwa nehucheche hwehuropi hunomira gliomas kana nemamwe mamiriro. Tarisa nechiremba wemwana wako kana mwana wako ane chero chinotevera:

• Dambudziko nekufamba kwemaziso (ziso rakatenderedzwa mukati).

• Matambudziko ekuona.

• Morning headache kana headache inoenda mushure mekurutsa.

• Kusvotwa uye kurutsa.

• Kurara zvisina kujairika.

• Kurasikirwa kwekukwanisa kufamba rimwe divi rechiso kana muviri.

• Kurasikirwa kwekuyera uye kunetseka kufamba.

• Simba rakawanda kana shoma pane zvakajairwa.

• Shanduko mumaitiro.

• Dambudziko kudzidza muchikoro.

Kuyedza kunoongorora huropi kunoshandiswa kuona (tsvaga) hudiki huropi hunodzika glioma.

Iyi inotevera bvunzo uye maitiro anogona kushandiswa:

• Kuongorora kwemuviri uye nhoroondo yehutano: Kuongororwa kwemuviri kutarisa zviratidzo zvehutano, kusanganisira kuongorora zviratidzo zvehosha, zvakadai semapundu kana chero chinhu chinoratidzika sechisina kujairika. Nhoroondo yemaitiro ehutano hwemurwere uye kurwara kwakapfuura uye kurapwa kuchatorwawo.

• Neurological bvunzo: akateedzana emibvunzo uye bvunzo kutarisa huropi, musana, uye tsinga basa. Bvunzo dzinoongorora chimiro chemunhu chepfungwa, kubatana, uye kugona kufamba zvakajairika, uye mashandiro, pfungwa, uye pfungwa zvinoshanda zvakadii. Izvi zvinogona zvakare kunzi bvunzo yeurouro kana bvunzo yetsinga.

• MRI (magnetic resonance imaging) ine gadolinium: Maitiro anoshandisa magineti, masaisai eredhiyo, uye komputa kugadzira akateedzana emifananidzo yakajeka yenzvimbo dziri mukati meuropi. Chinhu chinonzi gadolinium chinopinzwa mutsinga. Iyo gadolinium inounganidza yakatenderedza maseru ekenza kuitira kuti varatidze kupenya mumufananidzo. Iyi nzira inonziwo nyukireya magnetic resonance imaging (NMRI).

Biopsy inogona kuitwa kuti uongorore mamwe marudzi ehuropi stem glioma.

Kana iyo MRI scan ichitaridzika kunge bundu iri DIPG, biopsy haiwanzo kuitwa uye bundu haribviswe. Kana iyo MRI scan zvabuda zvisina chokwadi, biopsy inogona kuitwa.

Kana iyo MRI scan ichitaridzika senge yakakosha huropi stem glioma, biopsy inogona kuitwa. Chikamu chedehenya chinobviswa uye tsono inoshandiswa kubvisa sampuli yetishu dzehuropi. Dzimwe nguva, tsono inotungamirwa nekombuta. Nyanzvi yezvirwere anoona tishu pasi pe microscope kutsvaga maseru ekenza. Kana masero emukenza akawanikwa, chiremba achabvisa bundu rakawanda sezvinobvira panguva yekuvhiya kumwe chete.

Craniotomy: Kuvhura kunoitwa mu dehenya uye chidimbu chedehenya chinobviswa kuratidza chikamu chehuropi.

Chiyero chinotevera chingaitwe pane yemhando yemhando iyo yakabviswa panguva yebiopsy kana kuvhiyiwa:

• Immunohistochemistry: Kuongororwa kwerabhoritari inoshandisa masoja ekudzivirira mamwe maantigen (mamaki) mune imwe sampuro yetishu yemurwere. Masoja ekudzivirira chirwere anowanzo sunganidzwa ne enzyme kana dhayi ye fluorescent. Mushure mekunge maantibodies akasunga kune yakasarudzika antigen mune yeiyo sampuli, iyo enzyme kana dhayi inogoneswa, uye iyo antigen inogona kuzoonekwa pasi pe microscope. Rudzi urwu rweyedzo runoshandiswa kubatsira kuongorora gomarara uye kubatsira kutaurira imwe mhando yekenza kubva kune imwe mhando yegomarara.

Zvimwe zvinhu zvinokanganisa kufungidzira (mukana wekupora).

Kufungidzira kwemwana kunoenderana nezvinotevera:

• Rudzi rwehuropi stem glioma (DIPG kana focal glioma).

• Iko iko kuti bundu rinowanikwa muuropi uye kana rapararira mukati mehuropi.

• Zera remwana pakuongororwa.

• Inguva yakareba sei mwana ane zviratidzo asati aongororwa.

• Kunyangwe kana kwete mwana ane mamiriro anonzi neurofibromatosis mhando 1.

• Kunyangwe paine imwe shanduko mune H3 K27m geni.

• Kunyangwe bundu racho richangobva kuongororwa kana kuti radzokazve (dzoka).

Vazhinji vana vane DIPG vanorarama isingasviki mwedzi gumi nemasere mushure mekuongororwa. Vana vane focal glioma vanowanzo rarama makore anopfuura mashanu.

Matanho eUdiki Brain Stem Glioma

PFUNGWA DZINOKOSHA

• Chirongwa chekurapwa nekenza chinoenderana nekuti bundu iri mune imwe nzvimbo yehuropi here kana kuti rapararira mukati mehuropi.

Chirongwa chekurapwa nekenza chinoenderana nekuti bundu iri mune imwe nzvimbo yehuropi here kana kuti rapararira mukati mehuropi.

Staging ndiyo nzira inoshandiswa kuziva kuti gomarara rakawanda zvakadii uye kana gomarara rapararira. Izvo zvakakosha kuti uzive nhanho kuitira kuronga kurapwa.

Iko hakuna yakajairwa sisitimu sisitimu yehudiki huropi stem glioma. Kurapa kunoenderana nezvinotevera:

• Kunyangwe bundu iri richangobva kuongororwa kana kudzokororwa (rakadzoka mushure mekurapwa).

• Rudzi rwebundu (ingave inopararira yemukati pontine glioma kana focal glioma).

Iyo yakakosha huropi stem glioma inogona kudzoka makore mazhinji mushure mekutanga kurapwa. Bundu rinogona kudzoka muuropi kana mune mamwe matunhu epakati etsinga system. Musati wapiwa kurapwa kwekenza, kuongororwa kwekufungidzira, bhiopsy, kana kuvhiyiwa kunogona kuitwa kuti uve nechokwadi chekuti pane gomarara uye nekuziva kuti yakawanda sei gomarara.

Kurapa Sarudzo Kuongorora

PFUNGWA DZINOKOSHA

• Kune mhando dzakasiyana dzekurapa kwevana vane hutsi hwe stem glioma.

• Vana vane brain stem glioma vanofanirwa kurapwa kwavo kuchirongwa nechikwata chevanoona nezvehutano vari nyanzvi mukurapa

hura hwehuropi tumota.

• Mhando shanu dzekurapwa kwakajairika dzinoshandiswa:

• Kuvhiya

• Radiation kurapa

• Chemotherapy

• Cerebrospinal fluid kusiyanisa

• Kucherechedza

• Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

• Targeted kurapwa

• Kurapa kwehucheche huropi stem glioma kunogona kukonzera mhedzisiro.

• Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

• Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kenza kurapwa.

• Yekutevera-bvunzo inogona kudikanwa.

Kune mhando dzakasiyana dzekurapa kwevana vane hutsi hwe stem glioma.

Mhando dzakasiyana dzekurapa dzinowanikwa kune vana vane brain stem glioma. Mamwe marapirwo akajairwa (iko kurapwa kwazvino kwashandiswa), uye kumwe kuedzwa mumakiriniki ekuedzwa A kurapwa kiriniki kuyedzwa chidzidzo chekutsvaga chakaitirwa kubatsira kuvandudza marapirwo azvino kana kuwana ruzivo marapirwo matsva evarwere vane gomarara. Kana kiriniki miedzo ikaratidza kuti kurapwa kutsva kuri nani pane kwese kurapwa, kurapwa kutsva kunogona kuve kwakajairwa kurapwa.

Nekuti kenza muvana isingawanzo, kutora chikamu mukutongwa kwekiriniki kunofanirwa kutariswa. Mimwe miedzo yekiriniki yakavhurwa chete kune varwere vasina kutanga kurapwa.

Vana vane brain stem glioma vanofanirwa kurapwa kwavo kuchirongwa nechikwata chevanoona nezvehutano vari nyanzvi pakurapa hura hwehuropi.

Kurapa kunozoonekwa nachiremba wevana oncologist, chiremba ane hunyanzvi hwekurapa vana vane gomarara. Vanachiremba oncologist vanoshanda nevamwe vatapi vezvehutano vevana vanove nyanzvi dzekurapa vana vane mamota europi uye vanoziva mune dzimwe nzvimbo dzemishonga. Izvi zvinogona kusanganisira vanachiremba vanotevera:

• Chiremba wevana.

• Neurosurgeon.

• Neuropathologist.

• Chiremba radiation radiation.

• Neuro-oncologist.

• Neurologist.

• Neuroradiologist.

• Endocrinologist.

• Nyanzvi yezvepfungwa.

• Rehabilitation nyanzvi.

• Wezvemagariro.

• Mwana-hupenyu nyanzvi.

Mhando shanu dzekurapwa kwakajairika dzinoshandiswa:

Kuvhiya

Biopsy kana kuvhiya kubvisa DIPG hakuwanzo kuitwa nekuda kweinotevera:

• DIPG haisi imwechete misa. Inopararira pakati pemasero ane hutano muhuropi.

• Mabasa akakosha, senge kufema uye kurova kwemoyo kunogona kukanganiswa.

Bhiopsy yekuongorora kana kuvhiya kubvisa bundu ingangoshandiswa kwehucheche hwakatarisana nehuropi hunomira glioma.

Radiation kurapa

Radiation kurapa kurapwa kenza iyo inoshandisa yakakwira-simba x-rays kana mamwe marudzi e radiation kuuraya cancer maseru kana kuachengeta iwo kuti asakure. Kune mhando mbiri dze radiation radiation:

• External radiation therapy inoshandisa muchina uri kunze kwemuviri kutumira radiation kune kenza.

• Yemukati radiation kurapwa kunoshandisa radioactive chinhu chakavharirwa mune tsono, mhodzi, waya, kana makateti anoiswa akananga mukati kana padyo nekenza.

Maitiro ekurapwa nemwaranzi anoenderana nerudzi rwegomarara riri kurapwa. External radiation therapy inoshandiswa kurapa DIPG. Kunze uye / kana kwemukati radiation kurapwa kunogona kushandiswa kurapa kwakatarisana nehuropi stem gliomas.

Mwedzi yakati wandei mushure mekurapwa nemwaranzi kuuropi, bvunzo dzekufungidzira dzinogona kuratidza shanduko kumatishu ehuropi. Shanduko idzi dzinogona kukonzerwa ne radiation radiation kana zvinogona kureva kuti bundu riri kukura. Izvo zvakakosha kuti uve nechokwadi chekuti bundu riri kukura pasati paine imwezve kurapwa kunopihwa.

Chemotherapy

Chemotherapy mushonga wekenza unoshandisa mishonga kumisa kukura kwemasero ekenza, kungave nekuuraya maseru kana nekuamisa iwo kubva pakupatsanuka. Kana chemotherapy ikatorwa nemuromo kana kujowa mutsinga kana mhasuru, mishonga inopinda muropa uye inogona kusvika masero emukenza mumuviri wese (systemic chemotherapy). Kana chemotherapy ikaiswa yakanangana mucerebrospinal fluid, nhengo, kana dumbu remuviri senge dumbu, mishonga inokanganisa maseru egomarara munzvimbo idzodzo (chemotherapy yedunhu). Nzira iyo chemotherapy inopihwa inoenderana nemhando yekenza iri kurapwa.

Nekuti kurapa kwemwaranzi kuuropi kunogona kukanganisa kukura uye kukura kwehuropi muvana vadiki, chemotherapy inogona kupihwa kunonoka kana kudzikisa kudiwa kwe radiation radiation.

Cerebrospinal fluid kusiyanisa

Cerebrospinal fluid diversion inzira inoshandiswa kubvisa mvura yakavaka muuropi. Iyo shunt (yakareba, yakatetepa chubhu) inoiswa mune ventricle (nzvimbo inozadzwa nemvura) yehuropi uye yakasungirirwa pasi peganda kune chimwe chikamu chemuviri, kazhinji dumbu. Iyo shunt inotakura yakawedzera mvura kubva muuropi kuti igone kupinzwa kumwe kunhu mumuviri.

Cerebrospinal fluid (CSF) kusiyanisa. Yakawedzera CSF inobviswa kubva mu ventricle muuropi kuburikidza ne shunt (chubhu) uye inodururwa mudumbu. Avhavha inodzora kuyerera kweCSF.

Kucherechedza

Kucherechedza kuri kunyatsoongorora mamiriro emurwere pasina kupa chero kurapwa kusvikira zviratidzo kana zviratidzo zvaonekwa kana kuchinja.

Mhando nyowani dzekurapa dziri kuyedzwa mumakiriniki ekuedzwa.

Ichi chidimbu chikamu chinotsanangura kurapwa kuri kuongororwa mumakiriniki ekuedzwa. Zvinogona kusataura nezveese marapirwo matsva ari kuongororwa. Ruzivo nezve kiriniki miedzo inowanikwa kubva kuNCI webhusaiti.

Targeted kurapwa

Targeted therapy mhando yekurapa inoshandisa zvinodhaka kana zvimwe zvinhu kuti zvione uye kurwisa chaiwo maseru ekenza pasina kukuvadza zvakajairika maseru.

Kune mhando dzakasiyana dzeakanangwa kurapa kuri kudzidziswa mukurapa kwehuropi stem gliomas:

• Kinase inhibitor therapy inovhara mamwe mapuroteni, akadai seBRAF kana MEK, ayo anogona kubatsira kuchengetedza maseru emukenza kubva mukukura kana kupatsanuka. Dabrafenib (BRAF kinase inhibitor) uye trametinib (MEK kinase inhibitor) iri kuongororwa kuti irape ichangobva kuongororwa focal glioma uye inodzokororodza brain stem glioma.

• Histone deacetylase inhibitor (HDI) kurapa kunogona kumisa kukura kwemarara maseru nekuvharira mamwe ma enzymes anodiwa kuti sero kukura. Ichowo mhando yeangiogenesis mumiriri. Panobinostat iri kuongororwa mukurapa kweDIPG iyo isina kupindura kurapwa kana kudzokazve.

• Monoclonal antibody therapy inoshandisa masoja akagadzirwa murabhoritari kubva kune imwechete mhando yemasoja emuviri masero. Aya ma antibodies anokwanisa kuona zvinhu pane cancer cancer kana zvakajairika zvinhu zvinogona kubatsira gomarara maseru kukura. Masoja ekudzivirira chirwere anonamira pazvinhu uye anouraya maseru egomarara, anovharira kukura kwawo, kana kuti aachengetedze kubva pakupararira.

A monoclonal antibody, APX005M, inosunga CD40, cell cell receptor inowanikwa pane mamwe maseru ekudzivirira uye mamwe maseru ekenza. Inogona kurwisa cancer nekuwedzera immune system uye nekudzora cancer cancer kukura. Iri kudzidziswa mukurapa kwevana matumbo ehuropi ayo ari kukura, kupararira, kana kuwedzera (kufambira mberi), kana muDIPG ichangobva kuongororwa.

Kurapa kwehucheche huropi stem glioma kunogona kukonzera mhedzisiro.

Kuti uwane ruzivo nezve mhedzisiro inotanga panguva yekurapa kenza, ona yedu Side Mhedzisiro peji.

Zvimwe zvinokonzeresa kubva pakurapwa nekenza zvinotanga mushure mekurapwa uye kuenderera kwemwedzi kana makore zvinonzi kunonoka kuitika Mhedzisiro mhedzisiro inogona kusanganisira zvinotevera:

• Zvinetso zvepanyama.

• Shanduko mumanzwiro, manzwiro, kufunga, kudzidza, kana ndangariro.

• Gomarara repiri (mhando nyowani dzekenza).

Mimwe mhedzisiro mhedzisiro inogona kurapwa kana kudzorwa. Izvo zvakakosha kuti utaure navanachiremba vemwana wako nezve mhedzisiro yekurapwa nekenza kunogona kuve pamwana wako. (Ona pfupiso ye pamusoro peMagumo Ekurapa kweKenza Yevacheche kuti uwane rumwe ruzivo).

Varwere vangangoda kufunga nezve kutora chikamu mukutora kiriniki.

Ruzivo nezve kiriniki miedzo inowanikwa kubva kuNCI webhusaiti.

Kune vamwe varwere, kutora chikamu mumuedzo wekiriniki inogona kunge iri sarudzo yekurapa yakanyanya kunaka. Kliniki miedzo chikamu chekenza tsvagiridzo. Zvemakiriniki miedzo inoitwa kuti uone kana marapirwo matsva egomarara akachengeteka uye achishanda kana zvirinani pane akajairwa kurapwa.

Mazhinji emazuva ano marapirwo akajairwa ekenza akavakirwa pamavambo emakiriniki ekuedzwa. Varwere vanotora chikamu mukuyedzwa kwekiriniki vanogona kuwana kurapwa kwakaringana kana kuve pakati pevekutanga kurapwa kutsva.

Varwere vanotora chikamu mumiedzo yekiriniki zvakare vanobatsira kugadzirisa marapirwo achaitwa kenza mune ramangwana. Kunyangwe kana miedzo yemakiriniki isinga tangire kumarapirwo matsva anoshanda, anowanzo pindura mibvunzo yakakosha uye anobatsira kufambisira mberi kutsvagurudza.

Varwere vanogona kupinda mumakiriniki miedzo vasati, panguva, kana mushure mekutanga kwavo kenza kurapwa.

Mimwe miedzo yekiriniki inosanganisira chete varwere vasati vagamuchira kurapwa. Mimwe miedzo yekuedza kurapwa kwevarwere vane kenza haina kuve nani. Kune mamwezve emakiriniki miedzo inoedza nzira nyowani dzekumisa cancer kubva kudzokororazve (kudzoka) kana kudzikisira mhedzisiro yemakenza kurapwa.

Kuedzwa kwemakiriniki kuri kuitika munzvimbo zhinji dzenyika. Ruzivo nezve kiriniki miedzo inotsigirwa neNCI inogona kuwanikwa paNCI yekiriniki miedzo yekutsvaga peji rewebhu. Kliniki miedzo inotsigirwa nemamwe masangano inogona kuwanikwa pane yeClinicalTrials.gov webhusaiti.

Yekutevera-bvunzo inogona kudikanwa.

Mimwe miedzo yakaitwa kuongorora gomarara kana kutsvaga danho rekenza inogona kudzokororwa. Dzimwe bvunzo dzinodzokororwa kuitira kuti vaone kuti kurapa kuri kushanda sei. Sarudzo nezvekuti uenderere mberi, shandura, kana kumisa kurapwa kunogona kunge kuchibva pamhedzisiro yeiyi bvunzo.

Mimwe bvunzo ichaenderera ichiitwa nguva nenguva mushure mekunge kurapwa kwapera. Mhedzisiro yeiyi bvunzo inogona kuratidza kana mamiriro emwana wako achinja kana kana gomarara radzoka (dzoka). Iyi bvunzo dzimwe nguva inonzi yekuteedzera-bvunzo kana kuongorora-kumusoro.

Kana mhedzisiro yekufungidzira bvunzo yaitwa mushure mekurapwa kweDIPG ichiratidza huwandu muuropi, biopsy inogona kuitwa kuti uone kana yakaumbwa nematumbu akafa maseru kana kana masero emukenza matsva ari kukura. Muvana vanotarisirwa kurarama kwenguva yakareba, zvakajairika MRIs zvinogona kuitwa kuti vaone kana gomarara radzoka.

Kurapa kweDIPG

Kuti uwane ruzivo nezve marapirwo akanyorwa pazasi, ona iyo Chikamu Sarudzo Yekutarisa Chikamu.

Ichangoburwa kuongororwa kwehucheche inopararira mukati mehuropi stem glioma (DIPG) ibundu risina kurapwa kupihwa. Mwana anogona kunge akagamuchira mishonga kana kurapwa kubvisa zviratidzo kana zviratidzo zvinokonzerwa nebundu.

Kurapa kwakazara kweDIPG kunogona kusanganisira zvinotevera:

• External radiation kurapwa.

• Chemotherapy (mune vacheche).

• Kuongororwa kwekiriniki kwekurapwa kutsva.

Kurapa kweFocal Brain Stem Glioma

Achangobva kuongororwa hudiki focal glioma ibundu risina kurapwa kwakapihwa. Mwana anogona kunge akagamuchira mishonga kana kurapwa kubvisa zviratidzo kana zviratidzo zvinokonzerwa nebundu.

Kurapa kweiyo focal glioma kunogona kusanganisira zvinotevera:

• Kuvhiya kubvisa bundu kunogona kuteverwa nekemotherapy uye / kana yekunze radiation kurapwa.

• Kucherechedza kwemamota madiki anokura zvishoma nezvishoma. Cerebrospinal fluid diversion inogona kuitwa kana paine mamwe emvura muuropi.

• Yemukati radiation kurapwa neine radioactive mbeu, iine kana isina chemotherapy, apo bundu risingakwanise kubviswa nekuvhiyiwa.

• Kuongororwa kwekiriniki yekurapa kwakanangwa neBRAF kinase inhibitor (dabrafenib) inosanganiswa neMEK inhibitor (trametinib), kune mamwe mamota asingakwanise kubviswa nekuvhiya.

Kurapa kwehuropi stem glioma muvana vane neurofibromatosis mhando 1 inogona kunge iri yekutarisa. Mamota ari kunonoka-kukura muvana ava uye anogona kunge asingade kurapwa kwakaringana kwemakore.

Kurapa kwekufambira mberi kana kudzokorodza kwehudiki Brain Stem Glioma

Kana gomarara rikasava nani nekurapwa kana kudzoka, kurapwa kwekurapa chikamu chakakosha chehurongwa hwekurapa kwemwana. Inosanganisira kutsigira kwepanyama, kwepfungwa, kwemagariro, uye pamweya kwemwana nemhuri. Chinangwa chekuchengetedzwa kwekubatsira ndechekubatsira kudzora zviratidzo uye kupa mwana hwakanakisa hwehupenyu hunogoneka. Vabereki vangave vasina chokwadi nezvekuti varambe vachirapwa here kana kuti nderupi rudzi rwekurapa rwakanakira mwana wavo. Chikwata chezvehutano chinogona kupa vabereki ruzivo kuvabatsira kuita idzi sarudzo.

Mamwe maradhi ekurapa anogona kupihwa kune vana vane fambiro mberi kana inodzokororwa inopararira yemukati pontine glioma (DIPG) iyo yakapindura payakatanga kurapwa ne radiation radiation. Kurapa kweDIPG inofambira mberi kana inowanzoitika inogona zvakare kusanganisira zvinotevera:

• Kuongororwa kwekiriniki kunoongorora muyenzaniso wemota yemurwere kune mamwe magene ekuchinja. Rudzi rwekurapa kwakanangwa kuchapihwa kumurwere kunoenderana nerudzi rwechinjo yemajini.

• Kuongororwa kwekiriniki yekurapa kwakanangwa ne histone deacetylase inhibitor (panobinostat) kana monoclonal antibody (APX005M).

Kurapa kwekudzokorora kwakatarisana kwehucheche huropi stem glioma inogona kusanganisira zvinotevera:

• Kuvhiya kwechipiri kubvisa bundu.

• External radiation kurapwa.

• Chemotherapy.

• Kuongororwa kwekiriniki kunoongorora muyenzaniso wemota yemurwere kune mamwe magene ekuchinja. Rudzi rwekurapa kwakanangwa kuchapihwa kumurwere kunoenderana nerudzi rwechinjo yemajini.

Kuti Udzidze Zvakawanda Pamusoro Pehucheche Brain Tumors

Kuti uwane rumwe ruzivo nezve dumbu rehuropi tumota, ona zvinotevera:

• Chiremba Brain Tumor Consortium (PBTC) Buda Disclaimer

• Kutaurirana muCancer Care

• Kuronga Shanduko Kuguma-kwe-Hupenyu Kuchengeta mune Yakawedzera Kenza

• Chiremba Chekutsigira Kuchengeta (Kupera kweHupenyu Kuchengeta)

Kuti uwane rumwe ruzivo rwegomarara rehucheche uye zvimwe zvecancer zviwanikwa, ona zvinotevera:

• Nezve Kenza

• Cancers Yevacheche

• Kurapa Kutsvaga Kwevana Cancer Buda Disclaimer

• Mahedhi Ekupedzisira Ekurapwa kweKenza Yevacheche

• Vechidiki uye Vechidiki Vakuru vane Cancer

• Vana vane Cancer: Nhungamiro Yevabereki

• Kenza muVana neVachiri kuyaruka

• Stage

• Kurarama neCancer

• Mibvunzo Yekubvunza Wako Chiremba nezveCancer

• Kune Vakapona uye Vanotarisira