About-cancer / kurapwa / kiriniki-miedzo / chirwere / uterine-sarcoma / kurapwa
Kurapa Kliniki Miedzo yeUterine Sarcoma
Kliniki miedzo ndeyekutsvagisa zvidzidzo zvinosanganisira vanhu. Iwo makiriniki ekuedzwa pane ino rondedzero ndeyekurapa saroma sarcoma Yese miedzo pane irondedzero inotsigirwa neNCI.
Ruzivo rweNCI rwekutanga nezve zviedzo zvemakiriniki zvinotsanangura mhando nezvikamu zvemiyedzo uye maitirwo azvo. Kliniki miedzo inotarisa nzira nyowani dzekudzivirira, kuona, kana kubata chirwere. Iwe ungangoda kufunga nezve kutora chikamu mukutora kiriniki. Taura nachiremba wako kuti akubatsire kusarudza kana imwe yakakunakira iwe.
Miedzo 1-5 ye5
Nivolumab Mukurapa Varwere vane Metastatic kana Dzokororo Uterine Cancer
Ichi chikamu chechipiri cheyedzo yekuongorora kuti zvakanaka sei nivolumab inoshanda mukurapa varwere vane kenza yeutine yakapararira kune dzimwe nzvimbo mumuviri (metastatic) kana kudzoka mushure menguva yekuvandudza (inodzokororwa). Immunotherapy ine monoclonal antibodies, senge nivolumab, inogona kubatsira immune system kurwisa gomarara, uye inogona kukanganisa kugona kwesimba remarara kukura nekupararira.
Nzvimbo: 7 nzvimbo
Ipfupi Kosi Vaginal Cuff Brachytherapy Mukurapa Varwere vane Stage I-II Endometrial Kenza
Ichi chisinganzwisisike chikamu chechitatu cheyedzo yekuongorora kosi pfupi yemukadzi cuff brachytherapy kuti uone kuti inoshanda zvakadii kana ichienzaniswa neyakajairwa hanya vaginal cuff brachytherapy pakurapa varwere vane danho I-II gomarara remapetometri. Ipfupi kosi yemukadzi cuff brachytherapy, inozivikanwawo senge remukati kurapa kurapwa, inoshandisa (pamusoro penguva pfupi) radioactive zvinhu zvakaiswa mukati kana padyo nebundu muchikamu chepamusoro chemukadzi kuuraya tumarara maseru.
Nzvimbo: 7 nzvimbo
Kukurumidza Kuongorora uye Kupindura Kuongorora kweMubatanidzwa Anti-Neoplastic Agents muRare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib naPaclitaxel
Mhemberero: Vanhu vane kenza isingawanzo kuwanikwa kazhinji vane nzira shoma dzekurapa. Iyo biology yeasingawanzo kenza haina kunyatsonzwisiswa. Vanotsvaga vanoda kutsvaga zvirinani kurapwa kweizvi cancer. Ivo vanoda kuyedza 2 mishonga iyo, yakatorwa zvakasiyana, yakabatsira vanhu vane isina kujairika cancer. Vanoda kuona kana mishonga iyi pamwe chete ichigona kuita kuti kanzuru dzisingawanzo dzike kana kumira kukura. Chinangwa: Kudzidza kana nilotinib uye paclitaxel zvichabatsira vanhu vane kenza isingawanzo. Kukodzera: Vanhu vane makore gumi nemasere zvichikwira vane kenza isingawanzo, yepamusoro iyo yakafambira mberi mushure mekugamuchira kurapwa kwakaringana, kana iko kusina kurapwa kunoshanda. Dhizaini: Vatori vechikamu vanozoongororwa neyakaitika nhoroondo yezvokurapa uye bvunzo dzepanyama. Vanozoongororwa ropa uye weti. Vachave nemuedzo wepamuviri kana zvichidikanwa. Vachave neiyo electrocardiogram yekutarisa moyo yavo. Vachave nemifananidzo yekufungidzira kuyera mamota avo. Vatori vechikamu vanodzokorora bvunzo dzekuongorora panguva yechidzidzo. Vatori vechikamu vanogamuchira nilotinib uye paclitaxel. Iyo mishonga inopihwa mumazuva makumi maviri nemasere. Nilotinib kapisi inotorwa nemuromo kaviri pazuva. Paclitaxel ichapihwa mukati mehutachiona netambo yekumusoro kana wepakati mutsetse kamwe pavhiki kwemavhiki matatu ekutanga eimwe kutenderera. Vatori vechikamu vanochengeta diary yemishonga. Vanozoteedzera pavanotora mishonga yekudzidza uye chero mhedzisiro yavanogona kuve nayo. Vatori vechikamu vanogona kunge vaine sarudzo bundu biopsies. Vatori vechikamu vanogona kuramba vari pachidzidzo kudzamara chirwere chavo chanyanyisa kukura kana kuti vaine zvinokanganisika zvisingabvumike. Vatori vechikamu vanozoita yekutevera-kufona ingangoita mazuva makumi matatu mushure mekutora muyero wekupedzisira wemishonga yekudzidza. Vatori vechikamu vanogamuchira nilotinib uye paclitaxel. Iyo mishonga inopihwa mumazuva makumi maviri nemasere. Nilotinib kapisi inotorwa nemuromo kaviri pazuva. Paclitaxel ichapihwa mukati mehutachiona netambo yekumusoro kana wepakati mutsetse kamwe pavhiki kwemavhiki matatu ekutanga eimwe kutenderera. Vatori vechikamu vanochengeta diary yemishonga. Vanozoteedzera pavanotora mishonga yekudzidza uye chero mhedzisiro yavanogona kuve nayo. Vatori vechikamu vanogona kunge vaine sarudzo bundu biopsies. Vatori vechikamu vanogona kuramba vari pachidzidzo kudzamara chirwere chavo chanyanyisa kukura kana kuti vaine zvinokanganisika zvisingabvumike. Vatori vechikamu vanozoita yekutevera-kufona ingangoita mazuva makumi matatu mushure mekutora muyero wekupedzisira wemishonga yekudzidza. Vatori vechikamu vanogamuchira nilotinib uye paclitaxel. Iyo mishonga inopihwa mumazuva makumi maviri nemasere. Nilotinib kapisi inotorwa nemuromo kaviri pazuva. Paclitaxel ichapihwa mukati mehutachiona netambo yekumusoro kana wepakati mutsetse kamwe pavhiki kwemavhiki matatu ekutanga eimwe kutenderera. Vatori vechikamu vanochengeta diary yemishonga. Vanozoteedzera pavanotora mishonga yekudzidza uye chero mhedzisiro yavanogona kuve nayo. Vatori vechikamu vanogona kunge vaine sarudzo bundu biopsies. Vatori vechikamu vanogona kuramba vari pachidzidzo kudzamara chirwere chavo chanyanyisa kukura kana kuti vaine zvinokanganisika zvisingabvumike. Vatori vechikamu vanozoita yekutevera-kufona ingangoita mazuva makumi matatu mushure mekutora muyero wekupedzisira wemishonga yekudzidza. Paclitaxel ichapihwa mukati mehutachiona netambo yekumusoro kana wepakati mutsetse kamwe pavhiki kwemavhiki matatu ekutanga eimwe kutenderera. Vatori vechikamu vanochengeta diary yemishonga. Vanozoteedzera pavanotora mishonga yekudzidza uye chero mhedzisiro yavanogona kuve nayo. Vatori vechikamu vanogona kunge vaine sarudzo bundu biopsies. Vatori vechikamu vanogona kuramba vari pachidzidzo kudzamara chirwere chavo chanyanyisa kukura kana kuti vaine zvinokanganisika zvisingabvumike. Vatori vechikamu vanozoita yekutevera-kufona ingangoita mazuva makumi matatu mushure mekutora muyero wekupedzisira wemishonga yekudzidza. Paclitaxel ichapihwa mukati mehutachiona netambo yekumusoro kana wepakati mutsetse kamwe pavhiki kwemavhiki matatu ekutanga eimwe kutenderera. Vatori vechikamu vanochengeta diary yemishonga. Vanozoteedzera pavanotora mishonga yekudzidza uye chero mhedzisiro yavanogona kuve nayo. Vatori vechikamu vanogona kunge vaine sarudzo bundu biopsies. Vatori vechikamu vanogona kuramba vari pachidzidzo kudzamara chirwere chavo chanyanyisa kukura kana kuti vaine zvinokanganisika zvisingabvumike. Vatori vechikamu vanozoita yekutevera-kufona ingangoita mazuva makumi matatu mushure mekutora muyero wekupedzisira wemishonga yekudzidza.
Nzvimbo: National Institutes of Health Clinical Center, Bethesda, Maryland
Cabozantinib uye Temozolomide yeKurapa Kweusingagadzirisike kana Metastatic Leiomyosarcoma kana Zvimwe Zvakapfava Tissue Sarcoma
Ichi chikamu chechipiri cheyedzo yekuongorora mashandiro anoita cabozantinib uye temozolomide pakurapa varwere vane leiomyosarcoma kana imwe yakapfava tishu sarcoma iyo isingakwanise kubviswa nekuvhiya (kusinga gadzirisike) kana kupararira kune dzimwe nzvimbo mumuviri (metastatic). Cabozantinib inogona kumisa kukura kwemarara maseru nekuvhara mamwe ma enzymes anodiwa kuti sero kukura. Zvinodhaka zvinoshandiswa mukemotherapy, senge temozolomide, zvinoshanda munzira dzakasiyana kumisa kukura kwemarara maseru, kungave nekuuraya maseru, nekuamisa iwo kubva pakupatsanuka, kana nekuamisa iwo pakupararira. Kupa cabozantinib uye temozolomide kunogona kushanda zvirinani pane mumwe chete mukurapa varwere vane leiomyosarcoma kana imwe yakapfava tososoma sarcoma. Cabozantinib mushonga wekuferefeta,
Nzvimbo: 7 nzvimbo
Doxorubicin, AGEN1884, uye AGEN2034 yekurapwa kwePamberi kana Metastatic Soft Tissue Sarcoma
Ichi chikamu chechipiri cheyedzo yekuongorora mashandiro anoita doxorubicin pamwe neAGEN1884 uye AGEN2034 inoshanda mukurapa varwere vane zvinyoro zvinyama sarcoma yakapararira kune dzimwe nzvimbo mumuviri (advanced kana metastatic). Zvinodhaka zvinoshandiswa mu chemotherapy, senge doxorubicin, zvinoshanda munzira dzakasiyana kumisa kukura kwemarara maseru, kungave nekuuraya maseru, nekuamisa kuti asaparadzane, kana nekuamisa iwo kuti asapararire. Immunotherapy ine monoclonal antibodies, senge AGEN1884 uye AGEN2034, inogona kubatsira immune system kurwisa gomarara, uye inogona kukanganisa kugona kwesimba remarara kukura nekupararira. Kupa doxorubicin, AGEN1884, uye AGEN2034 kunogona kushanda zvirinani pakurapa varwere vane zvinyoro zvinyama sarcoma zvichienzaniswa ne doxorubicin chete.
Nzvimbo: ' Yunivhesiti yeColorado, Denver, Colorado
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