Ubwoko / bworoshye-tissue-sarcoma / umurwayi / rhabdomyosarcoma-kuvura-pdq

Umwana Rhabdomyosarcoma Umwana (®) - Indwara y'abarwayi

Amakuru Rusange Yerekeye Ubwana Rhabdomyosarcoma

Rhabdomyosarcoma yo mu bwana ni indwara ingirabuzimafatizo (kanseri) ziba mu ngingo z'imitsi.

Rhabdomyosarcoma ni ubwoko bwa sarcoma. Sarcoma ni kanseri yumubiri woroshye (nkimitsi), ingirangingo zihuza (nka tendon cyangwa karitsiye), cyangwa amagufwa. Rhabdomyosarcoma mubisanzwe itangirira mumitsi ifatanye namagufwa kandi ifasha umubiri kugenda. Rhabdomyosarcoma nubwoko busanzwe bwa sarcoma yoroheje yoroheje mubana. Irashobora gutangirira ahantu henshi mumubiri.

Hariho ubwoko butatu bwingenzi bwa rhabdomyosarcoma:

• Embryonal: Ubu bwoko buboneka cyane mumutwe no mumajosi cyangwa mubice byimyanya ndangagitsina cyangwa inkari, ariko birashobora kugaragara ahantu hose mumubiri. Nubwoko busanzwe bwa rhabdomyosarcoma.

• Alveolar: Ubu bwoko buboneka cyane mumaboko cyangwa amaguru, igituza, inda, imyanya ndangagitsina, cyangwa agace ka anal.

• Anaplastique: Ubu ni ubwoko busanzwe bwa rhabdomyosarcoma mubana.

Reba incamake yo kuvura ikurikira kugirango ubone amakuru yerekeye ubundi bwoko bwa tissue tissue sarcoma:

• Ubwana bworoheje Tissue Sarcoma

• Abakuze Boroheje Tissue Sarcoma

Imiterere imwe n'imwe ya genetike yongera ibyago byo kurwara rhabdomyosarcoma.

Ikintu cyose cyongera ibyago byo kwandura indwara cyitwa impanuka. Kugira ibintu bishobora guteza ibyago ntibisobanura ko uzarwara kanseri; kutagira ibyago bishobora gusobanura ko utazarwara kanseri. Vugana na muganga wumwana wawe niba utekereza ko umwana wawe ashobora guhura nibibazo.

Impamvu zishobora gutera rhabdomyosarcoma zirimo kugira indwara zikurikira:

• Indwara ya Li-Fraumeni.

• Pleuropulmonary blastoma.

• Neurofibromatose ubwoko bwa 1 (NF1).

• Indwara ya Costello.

• Indwara ya Beckwith-Wiedemann.

• Indwara ya Noonan.

Abana bafite ibiro byinshi byo kuvuka cyangwa binini kuruta uko byari byateganijwe kuvuka barashobora kugira ibyago byinshi byo kurwara rhabdomyosarcoma.

Kenshi na kenshi, icyateye rhabdomyosarcoma ntikiramenyekana.

Ikimenyetso cyubwana rhabdomyosarcoma nikibyimba cyangwa kubyimba bikomeza kuba binini.

Ibimenyetso nibimenyetso bishobora guterwa na rhabdomyosarcoma yo mu bwana cyangwa nibindi bihe. Ibimenyetso nibimenyetso bibaho biterwa na kanseri. Menyesha umuganga wumwana wawe niba umwana wawe afite kimwe muri ibi bikurikira:

• Ikibyimba cyangwa kubyimba bikomeza kuba binini cyangwa bitagiye. Birashobora kubabaza.

• Amaso.

• Kubabara umutwe.

• Ikibazo cyo kwihagarika cyangwa kugira amara.

• Amaraso mu nkari.

• Kuva amaraso mu mazuru, mu muhogo, mu gitsina, cyangwa mu mura.

Ibizamini byo gusuzuma hamwe na biopsy bikoreshwa mugushakisha (gushakisha) no gusuzuma rhabdomyosarcoma yo mu bwana.

Ibizamini byo gusuzuma bikozwe biterwa nuko kanseri ikomoka. Ibizamini hamwe nuburyo bukurikira birashobora gukoreshwa:

• Ikizamini cyumubiri namateka: Ikizamini cyumubiri kugirango ugenzure ibimenyetso rusange byubuzima, harimo no gusuzuma ibimenyetso byindwara, nkibibyimba cyangwa ikindi kintu cyose gisa nkidasanzwe. Hazafatwa kandi amateka yubuzima bwumurwayi nindwara zashize hamwe nubuvuzi.

• X-ray: X-ray yingingo namagufa imbere mumubiri, nkigituza. X-ray ni ubwoko bwingufu zishobora kunyura mumubiri no kuri firime, bigakora ishusho yibice byumubiri.

• CT scan (CAT scan): Uburyo bukora urukurikirane rwamashusho arambuye yibice byimbere mumubiri, nkigituza, inda, pelvis, cyangwa lymph node, byafashwe muburyo butandukanye. Amashusho yakozwe na mudasobwa ihujwe na mashini ya x-ray. Irangi rishobora guterwa mumitsi cyangwa kumirwa kugirango bifashe ingingo cyangwa ingirangingo kugaragara neza. Ubu buryo nabwo bwitwa computing tomografiya, tomografiya ya mudasobwa, cyangwa mudasobwa ya axial tomografiya.

Kubara tomografiya (CT) scan yinda. Umwana aryamye kumeza anyerera muri CT scaneri, ifata amashusho ya x-ray imbere yinda.

• MRI . Ubu buryo bwitwa kandi magnetic magnetic resonance imaging (NMRI).

Magnetic resonance imaging (MRI) yinda. Umwana aryamye kumeza anyerera muri scaneri ya MRI, ifata amashusho imbere yumubiri. Urupapuro ku nda yumwana rufasha gukora amashusho neza.

• PET scan (positron emission tomografi scan): Uburyo bwo kubona selile mbi yibibyimba mumubiri. Umubare muto wa glucose ikora radio (isukari) yatewe mumitsi. PET scaneri izenguruka umubiri kandi ikora ishusho yerekana aho glucose ikoreshwa mumubiri. Utugingo ngengabuzima twibibyimba twerekana neza cyane ku ishusho kuko zikora cyane kandi zifata glucose nyinshi kuruta selile zisanzwe.

Positron yoherejwe na tomografiya (PET) scan. Umwana aryamye kumeza anyerera muri PET scaneri. Kuruhuka umutwe hamwe nigitambara cyera bifasha umwana kuryama. Umubare muto wa glucose ikora radio (isukari) yatewe mumitsi yumwana, hanyuma scaneri ikora ishusho yerekana aho glucose ikoreshwa mumubiri. Ingirabuzimafatizo za kanseri zigaragara neza ku ishusho kuko zifata glucose nyinshi kuruta selile zisanzwe.

• Gusikana amagufwa: Uburyo bwo kugenzura niba mu magufwa hari selile zigabanya vuba, nka selile kanseri. Umubare muto cyane wibikoresho bya radio bitera mumitsi kandi bikanyura mumaraso. Ibikoresho bya radiyoyakusanyiriza mu magufa hamwe na kanseri kandi bigaragazwa na scaneri.

Gusikana amagufwa. Umubare muto wibikoresho bya radio bitera mumitsi yumwana kandi bikanyura mumaraso. Ibikoresho bya radiyo bikusanya mumagufwa. Mugihe umwana aryamye kumeza anyerera munsi ya scaneri, hamenyekana ibikoresho bya radio bikora amashusho bigakorerwa kuri ecran ya mudasobwa.

• Amagufa ya marrow aspiration na biopsy: Gukuraho igufwa ryamagufa, amaraso, nigice gito cyamagufwa winjiza urushinge rufunitse muri hipbone. Ingero zivanwa muri hipbone zombi. Inzobere mu by'indwara ireba amagufwa, amaraso, n'amagufwa munsi ya microscope kugira ngo ishakishe ibimenyetso bya kanseri.

Amagufa ya marrow icyifuzo na biopsy. Nyuma yuko agace gato k'uruhu kamaze kunanirwa, urushinge rw'amagufwa rwinjizwa mu igufwa ry'umwana. Ingero z'amaraso, amagufwa, n'amagufwa byavanyweho kugirango bisuzumwe kuri microscope.

• Gutobora Lumbar: Uburyo bukoreshwa mu gukusanya amazi ya cerebrospinal fluid (CSF) kuva kumugongo. Ibi bikorwa mugushira urushinge hagati yamagufa abiri murugongo no muri CSF ikikije uruti rwumugongo no gukuramo icyitegererezo cyamazi. Icyitegererezo cya CSF gisuzumwa munsi ya microscope kugirango ibimenyetso bya selile. Ubu buryo bwitwa LP cyangwa igikanda.

Niba ibi bizamini byerekana ko hashobora kubaho rhabdomyosarcoma, biopsy irakorwa. Biopsy ni ugukuraho selile cyangwa tissue kugirango zishobore kurebwa munsi ya microscope na patologue kugirango barebe ibimenyetso bya kanseri. Kubera ko kuvura biterwa n'ubwoko bwa rhabdomyosarcoma, ingero za biopsy zigomba kugenzurwa na psychologue ufite uburambe mu gusuzuma rhabdomyosarcoma.

Bumwe mu bwoko bukurikira bwa biopsies burashobora gukoreshwa:

• Ibyifuzo bya inshinge nziza (FNA) biopsy: Gukuraho tissue cyangwa fluid ukoresheje urushinge ruto.

• Biopsy yibanze: Gukuraho tissue ukoresheje urushinge runini. Ubu buryo bushobora kuyoborwa hakoreshejwe ultrasound, CT scan, cyangwa MRI.

• Fungura biopsy: Gukuraho tissue ukoresheje incike (gukata) bikozwe muruhu.

• Sentinel lymph node biopsy: Gukuraho lymph node ya sentinel mugihe cyo kubagwa. Sentinel lymph node niyambere ya lymph node mumatsinda ya lymph node yakira amazi ya lymphatique ava mubyimba byambere. Nibwo bwa mbere lymph node kanseri ishobora gukwirakwira kuva ikibyimba kibanza. Ikintu gikoresha radiyo na / cyangwa irangi ry'ubururu batewe inshinge hafi yikibyimba. Ibintu cyangwa irangi bitembera mumiyoboro ya lymph node. Lymph ya mbere yakira ibintu cyangwa irangi bivanwaho. Inzobere mu bijyanye n’indwara ireba ingirangingo ziri munsi ya microscope kugira ngo ishakishe kanseri. Niba kanseri ya kanseri itabonetse, ntibishobora kuba ngombwa gukuraho izindi lymph node. Rimwe na rimwe, lymph node ya sentinel iboneka mumatsinda arenze imwe.

Ibizamini bikurikira birashobora gukorwa kurugero rwa tissue yakuweho:

• Mikorosikopi yoroheje: Ikizamini cya laboratoire aho ingirabuzimafatizo zigaragara munsi ya microscopes isanzwe kandi ifite imbaraga nyinshi kugirango ishakishe impinduka zimwe na zimwe.

• Immunohistochemie: Ikizamini gikoresha antibodies kugirango ugenzure antigene zimwe murugero rwimitsi. Antibody isanzwe ihujwe nibintu bikoresha radio cyangwa irangi ritera ingirabuzimafatizo kumurika munsi ya microscope. Ubu bwoko bwikizamini bushobora gukoreshwa kugirango umenye itandukaniro riri hagati yubwoko butandukanye bwa kanseri.

• AMAFI (fluorescence in situ hybridisation): Ikizamini cya laboratoire ikoreshwa mu kureba gen cyangwa chromosomes mu ngirabuzimafatizo no mu ngingo. Ibice bya ADN birimo irangi rya fluorescent bikozwe muri laboratoire hanyuma byongerwamo selile cyangwa tissue kumurongo wikirahure. Iyo ibyo bice bya ADN bifatanye na gen cyangwa uduce twa chromosomes kumurongo, biramurika iyo urebye munsi ya microscope ifite urumuri rwihariye. Ubu bwoko bwikizamini bukoreshwa mugushakisha gene zimwe na zimwe.

• Guhindura transcription - polymerase urunigi rwerekana (RT - PCR) ikizamini: Ikizamini cya laboratoire aho ingirabuzimafatizo zicyitegererezo cyiga hakoreshejwe imiti kugirango harebwe impinduka zimwe mumiterere cyangwa imikorere ya gen.

• Isesengura rya Cytogenetike: Ikizamini cya laboratoire aho ingirabuzimafatizo zigaragara munsi ya microscope kugirango harebwe impinduka zimwe na zimwe muri chromosomes.

Ibintu bimwe bigira ingaruka kubitekerezo (amahirwe yo gukira) hamwe nuburyo bwo kuvura.

Kumenyekanisha (amahirwe yo gukira) hamwe nuburyo bwo kuvura biterwa nibi bikurikira:

• Imyaka yumurwayi.

• Aho mumubiri ikibyimba cyatangiriye.

• Ingano yikibyimba mugihe cyo gusuzuma.

• Niba ikibyimba cyavanyweho burundu kubagwa.

• Ubwoko bwa rhabdomyosarcoma (urusoro, alveolar, cyangwa anaplastique).

• Niba hari impinduka zimwe na zimwe muri gen.

• Niba ikibyimba cyarakwirakwiriye mu bindi bice by'umubiri mugihe cyo gusuzuma.

• Niba ikibyimba cyari muri lymph node mugihe cyo gusuzuma.

• Niba ikibyimba gisubiza chimiotherapie na / cyangwa imiti ivura imirasire.

Ku barwayi barwaye kanseri isubirwamo, guhanura no kuvura nabyo biterwa n'ibi bikurikira:

• Aho mumubiri ikibyimba cyongeye kugaruka (cyagarutse).

• Nigihe kingana iki hagati yo kurangiza kuvura kanseri nigihe kanseri yongeye.

• Niba ikibyimba cyavuwe hakoreshejwe imiti.

Icyiciro cyubwana Rhabdomyosarcoma

INGINGO Z'INGENZI

• Nyuma yo gupimwa rhabdomyosarcoma yo mu bwana, kuvura bishingiye ku gice cya kanseri kandi rimwe na rimwe bishingiye ku kumenya niba kanseri zose zarakuweho no kubagwa.

• Hariho uburyo butatu kanseri ikwirakwira mu mubiri.

• Kanseri irashobora gukwirakwira aho yatangiriye no mu bindi bice byumubiri.

• Gutegura ubwana rhabdomyosarcoma bikorwa mubice bitatu.

• Sisitemu yo kubika ishingiye ku bunini bw'ikibyimba, aho kiri mu mubiri, ndetse no kuba yarakwirakwiriye mu bindi bice by'umubiri:

• Icyiciro cya 1

• Icyiciro cya 2

• Icyiciro cya 3

• Icyiciro cya 4

• Sisitemu yo guteranya ishingiye ku kumenya niba kanseri yarakwirakwiriye kandi niba kanseri yose yarakuweho no kubagwa:

• Itsinda I.

• Itsinda rya II

• Itsinda III

• Itsinda rya IV

• Itsinda ryibyago rishingiye kuri sisitemu yo kubika hamwe na sisitemu yo guteranya.

• Rhabdomyosarcoma ifite ibyago bike

• Hagati-ibyago byabana rhabdomyosarcoma

• Rhabdomyosarcoma ifite ibyago byinshi

Nyuma yo gupimwa rhabdomyosarcoma yo mu bwana, kuvura bishingiye ku gice cya kanseri kandi rimwe na rimwe bishingiye ku kumenya niba kanseri zose zarakuweho no kubagwa.

Inzira ikoreshwa mu kumenya niba kanseri yarakwirakwiriye mu ngingo cyangwa mu bindi bice by'umubiri byitwa kubika. Ni ngombwa kumenya icyiciro kugirango utegure kuvura. Muganga azakoresha ibisubizo byibizamini byo gusuzuma kugirango afashe kumenya icyiciro cyindwara.

Umuti wo kuvura rhabdomyosarcoma ukiri muto ushingiye kubice bimwe na bimwe kuri stade ndetse rimwe na rimwe bikagereranywa na kanseri isigara nyuma yo kubagwa kugirango ikureho ikibyimba. Inzobere mu bijyanye n’indwara zizakoresha microscope kugira ngo isuzume ingirangingo zavanyweho mu gihe cyo kubagwa, harimo ingero za tissue ziva ku mpande z’aho kanseri yakuweho na lymph node. Ibi bikorwa kugirango harebwe niba selile zose za kanseri zasohotse mugihe cyo kubagwa.

Hariho uburyo butatu kanseri ikwirakwira mu mubiri.

Kanseri irashobora gukwirakwira binyuze mu ngingo, sisitemu ya lymph, n'amaraso:

• Tissue. Kanseri ikwirakwira aho yatangiriye ikurira mu turere twegereye.

• Sisitemu ya Lymph. Kanseri ikwirakwira aho yatangiriye yinjira muri sisitemu ya lymph. Kanseri inyura mu mitsi ya lymph igana mu bindi bice by'umubiri.

• Amaraso. Kanseri ikwirakwira aho yatangiriye yinjira mu maraso. Kanseri inyura mu mitsi y'amaraso igana mu bindi bice by'umubiri.

Kanseri irashobora gukwirakwira aho yatangiriye no mu bindi bice byumubiri.

Iyo kanseri ikwirakwira mu kindi gice cy'umubiri, yitwa metastasis. Ingirabuzimafatizo za kanseri zitandukana aho zatangiriye (ikibyimba kibanza) zikanyura muri sisitemu ya lymph cyangwa maraso.

Sisitemu ya Lymph. Kanseri yinjira muri sisitemu ya lymph, ikanyura mu mitsi ya lymph, igakora ikibyimba (ikibyimba metastatike) mu kindi gice cy'umubiri. Amaraso. Kanseri yinjira mu maraso, ikanyura mu mitsi y'amaraso, igakora ikibyimba (ikibyimba metastatike) mu kindi gice cy'umubiri. Ikibyimba metastatike nubwoko bumwe bwa kanseri nkibibyimba byibanze. Kurugero, niba rhabdomyosarcoma ikwirakwira mu bihaha, selile ya kanseri mu bihaha ni selile ya rhabdomyosarcoma. Indwara ni metastatike rhabdomyosarcoma, ntabwo ari kanseri y'ibihaha.

Gutegura ubwana rhabdomyosarcoma bikorwa mubice bitatu.

Rhabdomyosarcoma yo mu bwana ikorwa hakoreshejwe uburyo butatu bwo gusobanura kanseri:

• Sisitemu yo kubika.
• Sisitemu yo guteranya.
• Itsinda rishobora guteza akaga.

Sisitemu yo kubika ishingiye ku bunini bw'ikibyimba, aho kiri mu mubiri, ndetse no kuba yarakwirakwiriye mu bindi bice by'umubiri:

Icyiciro cya 1

Mu cyiciro cya 1, ikibyimba nubunini bwose, gishobora kuba cyarakwirakwiriye kuri lymph node, kandi kiboneka murimwe gusa murubuga rukurikira "rwiza":

• Ijisho cyangwa agace gakikije ijisho.

• Umutwe nijosi (ariko ntabwo biri mubice biri hafi yubwonko nu mugongo).

• Umuyoboro wa Gallbladder hamwe nuyoboro.

• Ureters cyangwa urethra.

• Ibizamini, intanga ngore, ibyara, cyangwa nyababyeyi.

Rhabdomyosarcoma ikora kurubuga "rwiza" ifite prognoz nziza. Niba urubuga kanseri ibera atari rumwe mu mbuga nziza zavuzwe haruguru, bivugwa ko ari urubuga "rutari rwiza".

Ingano ya Tumor ikunze gupimwa muri santimetero (cm) cyangwa santimetero. Ibiribwa bisanzwe bishobora gukoreshwa mu kwerekana ubunini bwikibyimba muri cm harimo: amashaza (cm 1), ibishyimbo (cm 2), umuzabibu (cm 3), walnut (cm 4), lime (cm 5 cyangwa 2 santimetero), igi (cm 6), amashaza (cm 7), n'imbuto (cm 10 cyangwa santimetero 4).

Icyiciro cya 2

Mu cyiciro cya 2, kanseri iboneka ku rubuga "rutameze neza" (ahantu hose hasobanuwe ko ari "byiza" mu cyiciro cya 1). Ikibyimba ntikirenza santimetero 5 kandi nticyigeze gikwirakwira.

Icyiciro cya 3

Mu cyiciro cya 3, kanseri iboneka ku rubuga "rutameze neza" (agace kamwe katavuzwe ko ari "keza" mu cyiciro cya 1) kandi kimwe muri ibi ni ukuri:

• Ikibyimba ntikirenza santimetero 5 kandi kanseri yakwirakwiriye hafi ya lymph node.

• Ikibyimba kirenze santimetero 5 kandi kanseri irashobora gukwirakwira hafi ya lymph node.

Icyiciro cya 4

Mu cyiciro cya 4, ikibyimba gishobora kuba kinini kandi kanseri ishobora gukwirakwira hafi ya lymph node. Kanseri yakwirakwiriye mu bice bya kure by'umubiri, nk'ibihaha, igufwa, cyangwa amagufwa.

Sisitemu yo guteranya ishingiye ku kumenya niba kanseri yarakwirakwiriye kandi niba kanseri yose yarakuweho no kubagwa:

Itsinda I.

Kanseri yabonetse gusa aho yatangiriye kandi yakuweho burundu no kubagwa. Tissue yakuwe kumpande zaho yakuye ikibyimba. Tissue yasuzumwe na microscope na patologue kandi nta kanseri ya kanseri yabonetse.

Itsinda rya II

Itsinda rya II rigabanyijemo amatsinda IIA, IIB, na IIC.

• IIA: Kanseri yakuweho no kubagwa ariko ingirangingo za kanseri zagaragaye igihe ingirangingo, zavanywe ku nkombe z'aho ikibyimba zavanywe, zarebwaga munsi ya microscope na patologue.

• IIB: Kanseri yari yarakwirakwiriye hafi ya lymph node kandi kanseri na lymph node byavanyweho kubagwa.

• IIC: Kanseri yari yarakwirakwiriye hafi ya lymph node, kanseri na lymph node byavanyweho no kubagwa, kandi byibura kimwe muri ibi bikurikira ni ukuri:

• Tissue yakuwe kumpande zaho yakuye ikibyimba yasuzumwe munsi ya microscope na patologue kandi kanseri ya kanseri iragaragara.

• Lymph node ya kure cyane yikibyimba yakuweho yasuzumwe munsi ya microscope na patologue kandi kanseri ya kanseri iragaragara.

Itsinda III

Kanseri yakuweho igice na biopsy cyangwa kubagwa ariko hasigaye ikibyimba gishobora kugaragara nijisho.

Itsinda rya IV

• Kanseri yari yarakwirakwiriye mu bice bya kure by'umubiri igihe basuzumaga kanseri.

• Ingirabuzimafatizo za kanseri ziboneka mu kizamini cyo gufata amashusho; cyangwa

Hano hari kanseri ya kanseri mumazi akikije ubwonko, uruti rw'umugongo, cyangwa ibihaha, cyangwa mumazi munda; cyangwa ibibyimba biboneka muri utwo turere.

Itsinda ryibyago rishingiye kuri sisitemu yo kubika hamwe na sisitemu yo guteranya.

Itsinda ryibyago risobanura amahirwe yuko rhabdomyosarcoma izagaruka (garuka). Umwana wese wavuwe na rhabdomyosarcoma agomba guhabwa chimiotherapie kugirango agabanye amahirwe ya kanseri. Ubwoko bw'imiti igabanya ubukana, ikinini, n'umubare w'imiti yatanzwe biterwa n’uko umwana afite ibyago bike, ibyago byo hagati, cyangwa rhabdomyosarcoma ifite ibyago byinshi.

Amatsinda akurikira akoreshwa:

Rhabdomyosarcoma ifite ibyago bike

• Rhabdomyosarcoma ifite ibyago bike byo mu bwana ni kimwe muri ibi bikurikira:

Ikibyimba cyo gusama kingana ubunini kiboneka kurubuga "rwiza". Hashobora kubaho ikibyimba gisigaye nyuma yo kubagwa gishobora kugaragara hamwe na microscope cyangwa idafite. Kanseri irashobora gukwirakwira hafi ya lymph node. Ibice bikurikira ni urubuga "rwiza":

• Ijisho cyangwa agace gakikije ijisho.

• Umutwe cyangwa ijosi (ariko ntabwo biri mubice hafi yugutwi, izuru, sinus, cyangwa umusingi wa gihanga).

• Umuyoboro wa Gallbladder hamwe nuyoboro.

• Ureter cyangwa urethra.

• Ibizamini, intanga ngore, ibyara, cyangwa nyababyeyi.

Ikibyimba cyo mu nda gifite ubunini butaboneka kurubuga "rwiza". Hashobora kubaho ikibyimba gisigaye nyuma yo kubagwa gishobora kugaragara gusa na microscope. Kanseri irashobora gukwirakwira hafi ya lymph node.

Hagati-ibyago byabana rhabdomyosarcoma

Hagati-ibyago-byana byana rhabdomyosarcoma nimwe muribi bikurikira:

• Ikibyimba cyo gusama gifite ubunini bwose butaboneka murimwe murubuga "rwiza" rwavuzwe haruguru. Hasigaye ikibyimba nyuma yo kubagwa, gishobora kugaragara hamwe na microscope cyangwa idafite. Kanseri irashobora gukwirakwira hafi ya lymph node.

• Ikibyimba cya alveolar gifite ubunini ubwo aribwo bwose "kurubuga" cyangwa "rubi". Hashobora kubaho ikibyimba gisigaye nyuma yo kubagwa gishobora kugaragara hamwe na microscope cyangwa idafite. Kanseri irashobora gukwirakwira hafi ya lymph node.

Rhabdomyosarcoma ifite ibyago byinshi

Rhabdomyosarcoma ifite ibyago byinshi byo mu bwana irashobora kuba ubwoko bw'inda cyangwa ubwoko bwa alveolar. Irashobora gukwirakwira hafi ya lymph node kandi ikwirakwira kuri kimwe cyangwa byinshi muribi bikurikira:

• Ibindi bice byumubiri bitari hafi yikibyimba cyatangiye.

• Amazi azenguruka ubwonko cyangwa uruti rw'umugongo.

• Amazi mu bihaha cyangwa munda.

Isubiramo Ryabana Rhabdomyosarcoma

Rhabdomyosarcoma isubira mu bwana ni kanseri yagarutse (garuka) imaze kuvurwa. Kanseri irashobora kugaruka ahantu hamwe cyangwa mu bindi bice byumubiri, nkibihaha, amagufwa, cyangwa igufwa. Kenshi na kenshi, rhabdomyosarcoma irashobora kugaruka mu ibere ku bagore b'ingimbi cyangwa mu mwijima.

Incamake yo kuvura

INGINGO Z'INGENZI

• Hariho uburyo butandukanye bwo kuvura abarwayi bafite rhabdomyosarcoma yo mu bwana.

• Abana barwaye rhabdomyosarcoma bagomba kwivuza bategurwa nitsinda ryabatanga ubuvuzi ninzobere mu kuvura kanseri mu bana.

• Umuti wa rhabdomyosarcoma ukiri muto urashobora gutera ingaruka.

• Ubwoko butatu bwo kuvura busanzwe bukoreshwa:

• Kubaga

• Imiti ivura imirasire

• Chimoterapi

• Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.

• Immunotherapy

• Ubuvuzi bugamije

• Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.

• Abarwayi barashobora kwipimisha kwa muganga mbere, mugihe, cyangwa nyuma yo gutangira kuvura kanseri.

• Ibizamini byo gukurikirana birashobora gukenerwa.

Hariho uburyo butandukanye bwo kuvura abarwayi bafite rhabdomyosarcoma yo mu bwana.

Bumwe mu buryo busanzwe (ubuvuzi bukoreshwa ubu), kandi bumwe burimo kugeragezwa mubigeragezo byamavuriro. Ikigeragezo kivura ni ubushakashatsi bwakozwe bugamije gufasha kunoza imiti igezweho cyangwa kubona amakuru ku buvuzi bushya ku barwayi ba kanseri. Iyo ibizamini byo kwa muganga byerekana ko ubuvuzi bushya buruta ubuvuzi busanzwe, ubuvuzi bushya bushobora kuba ubuvuzi busanzwe.

Kubera ko kanseri mu bana idasanzwe, kugira uruhare mu igeragezwa ry’amavuriro bigomba kwitabwaho. Ibigeragezo bimwe na bimwe bivura abarwayi batatangiye kwivuza.

Abana barwaye rhabdomyosarcoma bagomba kwivuza bategurwa nitsinda ryabatanga ubuvuzi ninzobere mu kuvura kanseri mu bana.

Kuberako rhabdomyosarcoma ishobora gukora mubice byinshi bitandukanye byumubiri, hakoreshwa uburyo bwinshi bwo kuvura. Umuti uzakurikiranwa n’umuganga w’abana oncologue, umuganga winzobere mu kuvura abana barwaye kanseri. Oncologue wabana akorana nabandi bashinzwe ubuvuzi bafite ubuhanga bwo kuvura abana barwaye rhabdomyosarcoma kandi bazobereye mubice bimwe na bimwe byubuvuzi. Aba bashobora kuba barimo inzobere zikurikira:

• Umuganga w'abana.

• Umuganga ubaga abana.

• Imirasire ya oncologue.

• Inzobere mu kuvura indwara z'abana.

• Radiologue y'abana.

• Inzobere mu baforomo b'abana.

• Umujyanama wa geneti cyangwa kanseri genetics umujyanama wibyago.

• Ushinzwe imibereho myiza.

• Inzobere mu gusubiza mu buzima busanzwe.

Umuti wa rhabdomyosarcoma ukiri muto urashobora gutera ingaruka.

Kumakuru yingaruka zitangira mugihe cyo kuvura kanseri, reba urupapuro rwuruhande rwacu.

Ingaruka ziterwa no kuvura kanseri zitangira nyuma yo kuvurwa zikomeza amezi cyangwa imyaka byitwa ingaruka zitinze. Ingaruka zitinze zo kuvura kanseri kuri rhabdomyosarcoma zishobora kubamo:

• Ibibazo byumubiri.

• Impinduka mumyumvire, ibyiyumvo, gutekereza, kwiga, cyangwa kwibuka.

• Kanseri ya kabiri (ubwoko bushya bwa kanseri).

Ingaruka zimwe zitinze zishobora kuvurwa cyangwa kugenzurwa. Ni ngombwa kuganira n'abaganga b'umwana wawe ku ngaruka kuvura kanseri bishobora kugira ku mwana wawe. (Reba incamake ya ku ngaruka zitinze zo kuvura kanseri y'abana kugira ngo umenye amakuru.)

Ubwoko butatu bwo kuvura busanzwe bukoreshwa:

Kubaga

Kubaga (gukuraho kanseri mu gikorwa) bikoreshwa mu kuvura rhabdomyosarcoma yo mu bwana. Ubwoko bwo kubaga bwitwa kwaguka bwaho bukunze gukorwa. Igice kinini cyaho ni ugukuraho ikibyimba hamwe na tissue zimwe na zimwe ziyikikije, harimo na lymph node. Kubaga ubwa kabiri birashobora gukenerwa kugirango ukureho kanseri yose. Niba kubaga bikozwe n'ubwoko bwo kubaga bwakozwe biterwa n'ibi bikurikira:

• Aho mumubiri ikibyimba cyatangiriye.

• Ingaruka zo kubagwa zizagira muburyo umwana azaba asa.

• Ingaruka kubaga bizagira ku mikorere y'ingenzi y'umwana.

• Uburyo ikibyimba cyakiriye chimiotherapie cyangwa imiti ivura imirasire ishobora kuba yatanzwe mbere.

Mu bana benshi barwaye rhabdomyosarcoma, ntibishoboka gukuramo ibibyimba byose kubagwa.

Rhabdomyosarcoma irashobora gushingwa ahantu henshi hatandukanye mumubiri kandi kubaga bizaba bitandukanye kuri buri rubuga. Kubaga kuvura rhabdomyosarcoma yijisho cyangwa imyanya ndangagitsina ni biopsy. Chimiotherapie, ndetse rimwe na rimwe ivura imirasire, irashobora gutangwa mbere yo kubagwa kugirango igabanye ibibyimba binini.

Muganga amaze gukuraho kanseri yose ishobora kugaragara mugihe cyo kubagwa, abarwayi bazahabwa chimiotherapie nyuma yo kubagwa kugirango bice selile zose zisigaye. Imiti ivura imirasire irashobora kandi gutangwa. Umuti watanzwe nyuma yo kubagwa, kugirango ugabanye ibyago ko kanseri izagaruka, byitwa kuvura indwara.

Imiti ivura imirasire

Imishwarara ivura ni imiti ikoresha kanseri ikoresha ingufu za x-imirasire cyangwa ubundi bwoko bwimirasire yica kanseri cyangwa ikabuza gukura. Hariho ubwoko bubiri bwo kuvura imirasire:

• Imiti ivura hanze ikoresha imashini hanze yumubiri kugirango yohereze imirasire kuri kanseri. Uburyo bumwe na bumwe bwo gutanga imishwarara irashobora gufasha kurinda imirasire kwangiza ingirabuzimafatizo nziza. Ubu bwoko bwo kuvura imirasire yo hanze burimo ibi bikurikira:

• Ubuvuzi bwa radiyoyose: Ubuvuzi bwa radiyoyumu ni ubwoko bwimiti ivura imishwarara yo hanze ikoresha mudasobwa mugukora ishusho ya 3-D (D-D) ishusho yikibyimba kandi igakora imirasire yimirasire kugirango ihuze ikibyimba. Ibi bituma urugero rwinshi rwimirasire rugera kumibyimba kandi bigatera kwangirika kwinyama nzima hafi.

• Imiti ivura imishwarara ikabije (IMRT): IMRT ni ubwoko bwimiti 3 (3-D) ivura imirasire ikoresha mudasobwa mugukora amashusho yubunini nuburyo imiterere yikibyimba. Imirasire yoroheje yimirasire yububasha butandukanye (imbaraga) igamije kubyimba uhereye kumpande nyinshi.

• Volumetrical modulated arc therapy (VMAT): VMAT ni ubwoko bwa 3-D ivura imirasire ikoresha mudasobwa mugukora amashusho yubunini n'imiterere yibibyimba. Imashini yimirasire igenda muruziga ruzengurutse umurwayi rimwe mugihe cyo kuvura kandi ikohereza imirasire yoroheje yimirasire yububasha butandukanye (imbaraga) kumubyimba. Umuti hamwe na VMAT utangwa byihuse kuruta kuvura hamwe na IMRT.

• Ubuvuzi bwa stereotactique yumubiri: Ubuvuzi bwimirasire yumubiri ni ubwoko bwimiti ivura hanze. Ibikoresho bidasanzwe bikoreshwa mugushira umurwayi mumwanya umwe kuri buri kuvura imirasire. Rimwe kumunsi muminsi myinshi, imashini imirasire igamije kurenza urugero rusanzwe rwimirasire yibibyimba. Mugihe umurwayi afite umwanya umwe kuri buri kuvura, nta byangiritse cyane kumubiri muzima uri hafi. Ubu buryo bwitwa kandi stereotactique yo hanze-beam ivura imishwarara hamwe nubuvuzi bwa stereotaxic.

• Imiti ivura imirasire ya proton: Ubuvuzi bwa proton-beam ni ubwoko bwingufu nyinshi, imiti ivura hanze. Imashini ivura imirasire igamije imigezi ya proton (utuntu duto, tutagaragara, twuzuye neza) kuri selile ya kanseri kugirango tubice. Ubu bwoko bwo kuvura butera kwangirika kwinyama nzima hafi.

• Imiti ivura imbere ikoresha ibintu bifata radiyo bifunze inshinge, imbuto, insinga, cyangwa catheteri bishyirwa muri kanseri cyangwa hafi yayo. Ikoreshwa mu kuvura kanseri ahantu nko mu gitsina, igituba, nyababyeyi, uruhago, prostate, umutwe, cyangwa ijosi. Imiti ivura imbere nayo yitwa brachytherapy, imirasire yimbere, imirasire yatewe, cyangwa imiti ivura imirasire.

Ubwoko nubunini bwimiti ivura imirasire nigihe itanzwe biterwa nimyaka yumwana, ubwoko bwa rhabdomyosarcoma, aho mumubiri ikibyimba cyatangiriye, uko ikibyimba cyagumye nyuma yo kubagwa, kandi niba hari ikibyimba mumitsi ya lymph hafi. .

Ubuvuzi bwo hanze bushobora gukoreshwa mu kuvura rhabdomyosarcoma yo mu bwana ariko rimwe na rimwe hakoreshwa imiti ivura imirasire y'imbere.

Chimoterapi

Chimoterapi ni umuti wa kanseri ukoresha ibiyobyabwenge kugirango uhagarike imikurire ya kanseri, haba mu kwica selile cyangwa kubabuza gutandukana. Iyo chimiotherapie ifashwe numunwa cyangwa igaterwa mumitsi cyangwa imitsi, imiti yinjira mumaraso kandi irashobora kugera kanseri ya kanseri mumubiri (chimiotherapie sisitemu). Iyo chimiotherapie ishyizwe mumazi yubwonko, urugingo, cyangwa umwobo wumubiri nkinda, imiti yibasira kanseri ya kanseri muri utwo turere (chimiotherapie yo mukarere).

Chimiotherapie irashobora kandi gutangwa kugirango igabanye ikibyimba mbere yo kubagwa kugirango ibike ingirabuzimafatizo nziza zishoboka. Ibi bita chimiotherapie neoadjuvant.

Umwana wese wavuwe na rhabdomyosarcoma agomba guhabwa imiti ya chimiotherapie kugirango agabanye amahirwe kanseri yongera. Ubwoko bw'imiti igabanya ubukana, ikinini, n'umubare w'imiti yatanzwe biterwa n’uko umwana afite ibyago bike, ibyago byo hagati, cyangwa rhabdomyosarcoma ifite ibyago byinshi.

Reba Ibiyobyabwenge Byemewe kuri Rhabdomyosarcoma kubindi bisobanuro.

Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.

Iki gice cyincamake gisobanura imiti irimo kwigwa mubigeragezo byamavuriro. Ntishobora kuvuga ubuvuzi bushya burimo kwigwa. Amakuru yerekeye ibizamini byamavuriro araboneka kurubuga rwa NCI.

Immunotherapy

Immunotherapy nubuvuzi bukoresha sisitemu yumubiri yumurwayi kurwanya kanseri. Ibintu bikozwe numubiri cyangwa bikozwe muri laboratoire bikoreshwa mukuzamura, kuyobora, cyangwa kugarura umubiri kamere irinda kanseri. Ubu bwoko bwo kuvura kanseri nabwo bwitwa biologic therapy cyangwa biotherapy.

Hariho ubwoko butandukanye bwikingira:

• Ubuvuzi bwinkingo nubuvuzi bwa kanseri bukoresha ibintu cyangwa itsinda ryibintu kugirango bikangure sisitemu yumubiri kugirango ibone ikibyimba ikice. Ubuvuzi bwinkingo burimo kwigwa kuvura metastatike rhabdomyosarcoma.

• Immune checkpoint inhibitor therapy ikoresha sisitemu yumubiri yumubiri kugirango yice kanseri. Ubwoko bubiri bwikingira ryikingira burimo kwigwa mukuvura rhabdomyosarcoma yo mu bwana yagarutse nyuma yo kuvurwa:

• CTLA-4 ni poroteyine hejuru ya selile T ifasha kugenzura ubudahangarwa bw'umubiri. Iyo CTLA-4 ifashe indi poroteyine yitwa B7 kuri selile ya kanseri, ibuza selile T kwica kanseri. Inzitizi za CTLA-4 zifatanije na CTLA-4 kandi zemerera selile T kwica kanseri. Ipilimumab ni ubwoko bwa CTLA-4 inhibitor.

Immune igenzura. Intungamubiri za poroteyine, nka B7-1 / B7-2 kuri selile zerekana antigen (APC) na CTLA-4 kuri selile T, zifasha kugenzura ubudahangarwa bw'umubiri. Iyo reseptor ya T-selile (TCR) ihuza na poroteyine za antigen hamwe ningenzi zikomeye za histocompatibilité (MHC) kuri APC na CD28 zihuza B7-1 / B7-2 kuri APC, selile T irashobora gukora. Ariko, guhuza B7-1 / B7-2 na CTLA-4 bituma selile T zidakora kuburyo zidashobora kwica selile yibibyimba mumubiri (panne ibumoso). Guhagarika guhuza B7-1 / B7-2 na CTLA-4 hamwe na inhibitor igenzura (antibody anti-CTLA-4) ituma selile T ikora kandi ikica selile yibibyimba (panel iburyo).

• PD-1 ni poroteyine hejuru ya selile T ifasha kugenzura ubudahangarwa bw'umubiri. Iyo PD-1 ifatanye nindi poroteyine yitwa PDL-1 kuri selile ya kanseri, ihagarika selile T kwica kanseri. Inzitizi za PD-1 zifatanije na PDL-1 kandi zemerera selile T kwica selile. Nivolumab na pembrolizumab ni PD-1 inhibitor.

Immune igenzura. Intungamubiri za poroteyine, nka PD-L1 ku ngirabuzimafatizo na PD-1 kuri selile T, zifasha kugenzura ibisubizo by’ubudahangarwa. Guhambira PD-L1 na PD-1 bituma selile T itica selile yibibyimba mumubiri (panne ibumoso). Guhagarika guhuza PD-L1 na PD-1 hamwe na inhibitor igenzura (anti-PD-L1 cyangwa anti-PD-1) ituma selile T yica selile yibibyimba (panne iburyo).

Ubuvuzi bugamije

Ubuvuzi bugamije ni uburyo bwo kuvura bukoresha ibiyobyabwenge cyangwa ibindi bintu byibasira kanseri. Ubuvuzi bugamije ubusanzwe butera kwangirika kwingirabuzimafatizo zisanzwe kuruta chimiotherapie cyangwa imirasire. Hariho ubwoko butandukanye bwo kuvura:

• MTOR inhibitor ihagarika poroteyine ifasha selile kugabana no kubaho. Sirolimus ni ubwoko bwa mTOR inhibitor therapy yizwe mukuvura rhabdomyosarcoma isubirwamo.

• Inzitizi ya Tyrosine kinase ni imiti mito-ya molekile inyura mu ngirabuzimafatizo kandi ikorera mu ngirabuzimafatizo za kanseri kugira ngo ibuze ibimenyetso byerekana ko kanseri ikeneye gukura no kugabana. MK-1775 na cabozantinib-s-malate ni tyrosine kinase inhibitor yiga mukuvura rhabdomyosarcoma.

Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.

Ku barwayi bamwe, kwitabira ikizamini cyamavuriro birashobora kuba uburyo bwiza bwo kuvura. Ibigeragezo bivura biri mubikorwa byubushakashatsi bwa kanseri. Igeragezwa rya Clinical rikorwa kugirango hamenyekane niba imiti mishya ya kanseri itekanye kandi ifite akamaro cyangwa nziza kuruta ubuvuzi busanzwe.

Benshi mubuvuzi busanzwe bwa kanseri bushingiye kubigeragezo byambere byubuvuzi. Abarwayi bitabiriye kwipimisha barashobora kuvurwa bisanzwe cyangwa kuba mubambere bahawe imiti mishya.

Abarwayi bitabira ibizamini byo kwa muganga nabo bafasha kunoza uburyo kanseri izavurwa mugihe kizaza. Nubwo ibigeragezo bivura bitaganisha ku buvuzi bushya, akenshi basubiza ibibazo byingenzi kandi bigafasha gutera imbere ubushakashatsi.

Abarwayi barashobora kwipimisha kwa muganga mbere, mugihe, cyangwa nyuma yo gutangira kuvura kanseri.

Igeragezwa rimwe na rimwe ririmo abarwayi bataravurwa. Ibindi bigeragezo bipima abarwayi bafite kanseri itameze neza. Hariho kandi ibizamini byo kwa muganga bipima uburyo bushya bwo guhagarika kanseri kongera kugaruka (kugaruka) cyangwa kugabanya ingaruka zo kuvura kanseri.

Igeragezwa rya Clinical ririmo kubera mu bice byinshi by'igihugu. Amakuru yerekeye ibizamini byamavuriro ashyigikiwe na NCI urashobora kubisanga kurubuga rwa NCI. Ibizamini bya Clinical bishyigikiwe nandi mashyirahamwe murashobora kubisanga kurubuga rwa ClinicalTrials.gov.

Ibizamini byo gukurikirana birashobora gukenerwa.

Bimwe mubizamini byakozwe mugupima kanseri cyangwa kumenya icyiciro cya kanseri birashobora gusubirwamo. Ibizamini bimwe bizasubirwamo kugirango harebwe uburyo ubuvuzi bukora neza. Ibyemezo bijyanye no gukomeza, guhindura, cyangwa guhagarika ubuvuzi birashobora gushingira kubisubizo byibi bizamini.

Bimwe mubizamini bizakomeza gukorwa buri gihe nyuma yubuvuzi burangiye. Ibisubizo by'ibi bizamini birashobora kwerekana niba imiterere y'umwana wawe yarahindutse cyangwa niba kanseri yarongeye (garuka). Ibi bizamini rimwe na rimwe byitwa gukurikirana-ibizamini cyangwa kugenzura.

Amahitamo yo kuvura Rhabdomyosarcoma

Muri iki gice

• Mbere Ubuzima butavuwe Rhabdomyosarcoma

• Kwanga cyangwa Gusubiramo Ubwana Rhabdomyosarcoma

Kumakuru yerekeye imiti yavuzwe hepfo, reba igice cyo kuvura.

Mbere Ubuzima butavuwe Rhabdomyosarcoma

Kuvura rhabdomyosarcoma yo mu bwana akenshi birimo kubaga, kuvura imirasire, hamwe na chimiotherapie. Uburyo ubwo buvuzi butangwa buterwa n’aho mu mubiri ikibyimba cyatangiriye, ingano yikibyimba, ubwoko bwikibyimba, ndetse n’uko ikibyimba cyakwirakwiriye mu mitsi cyangwa mu bindi bice byumubiri. Reba uburyo bwo kuvura uburyo bwo kuvura igice cyincamake kugirango umenye amakuru yerekeye kubaga, kuvura imirasire, hamwe na chimiotherapie ikoreshwa mu kuvura abana barwaye rhabdomyosarcoma.

Rhabdomyosarcoma y'ubwonko n'umutwe nijosi

• Ku bibyimba byo mu bwonko: Ubuvuzi bushobora kubamo kubaga ikibyimba, kuvura imirasire, hamwe na chimiotherapie.

• Kubibyimba byo mumutwe no mumajosi biri mumaso cyangwa hafi yijisho: Ubuvuzi bushobora kubamo chimiotherapie hamwe nubuvuzi bwimirasire. Niba ikibyimba kigumye cyangwa kigarutse nyuma yo kuvurwa hakoreshejwe imiti ya chimiotherapie hamwe nubuvuzi bwimirasire, kubagwa kugirango ukureho ijisho hamwe nuduce tumwe na tumwe dukikije ijisho.

• Kubibyimba byo mumutwe nijosi biri hafi yugutwi, izuru, sinus, cyangwa umusingi wigihanga ariko bitari mumaso cyangwa hafi yijisho: Ubuvuzi bushobora kubamo kuvura imirasire hamwe na chimiotherapie.

• Kubibyimba byo mumutwe no mumajosi bitari mumaso cyangwa hafi yijisho kandi bitari hafi yugutwi, izuru, sinus, cyangwa umusingi wigihanga: Ubuvuzi bushobora kuba bukubiyemo chimiotherapie, imiti ivura imirasire, hamwe no kubagwa kugirango ikureho ikibyimba.

• Ku bibyimba byo mu mutwe no mu ijosi bidashobora gukurwaho no kubagwa: Ubuvuzi bushobora kuba bukubiyemo imiti ya chimiotherapie hamwe n’imiti ivura imirasire harimo no kuvura imirasire ya stereotactique.

• Kubibyimba byo mu kanwa (agasanduku k'ijwi): Ubuvuzi bushobora kuba bukubiyemo imiti ya chimiotherapie hamwe n'imiti ivura imirasire. Kubagwa kugirango bakureho umunwa mubisanzwe ntibikorwa, kugirango ijwi ritangirika.

Rhabdomyosarcoma y'amaboko cyangwa amaguru

• Chimiotherapie ikurikirwa no kubagwa kugirango ikureho ikibyimba. Niba ikibyimba kitakuweho burundu, hashobora gukorwa kubagwa kabiri. Imiti ivura imirasire irashobora kandi gutangwa.

• Kubibyimba byintoki cyangwa ikirenge, imiti ivura imirasire hamwe na chimiotherapie irashobora gutangwa. Ikibyimba ntigishobora kuvaho kuko cyagira ingaruka kumikorere yukuboko cyangwa ikirenge.

• Indwara ya Lymph node (imwe cyangwa nyinshi ya lymph node ikurwaho hanyuma hagasuzumwa urugero rwa tissue munsi ya microscope kugirango ibimenyetso bya kanseri).

• Kubibyimba biri mumaboko, lymph node hafi yikibyimba no mumaboko yakuweho.

• Kubibyimba mumaguru, lymph node hafi yikibyimba no mugice cya ruhago.

Rhabdomyosarcoma yigituza, inda, cyangwa igituba

• Kubibyimba mu gituza cyangwa munda (harimo urukuta rw'igituza cyangwa urukuta rw'inda): Kubaga (kwaguka kwagutse). Niba ikibyimba ari kinini, chimiotherapie hamwe nubuvuzi bwimirasire bihabwa kugabanya ikibyimba mbere yo kubagwa.

• Kubibyimba byo munda: Kubaga (kwaguka kwagutse) birashobora gukorwa. Niba ikibyimba ari kinini, chimiotherapie itangwa kugirango igabanye ikibyimba mbere yo kubagwa. Imiti ivura imirasire irashobora gutangwa nyuma yo kubagwa.

• Kubibyimba bya diaphragm: Biopsy yikibyimba ikurikirwa na chimiotherapie hamwe nubuvuzi bwimirasire kugirango igabanye ikibyimba. Kubaga birashobora gukorwa nyuma kugirango bikureho selile zose zisigaye.

• Kubibyimba bya gallbladder cyangwa umuyoboro wa bile: Biopsy yikibyimba ikurikirwa na chimiotherapie hamwe nubuvuzi bwimirasire.

• Kubibyimba by'imitsi cyangwa ingirangingo zikikije anus cyangwa hagati yigituba na anus cyangwa scrotum na anus: Kubagwa bikorwa kugirango ukureho ibibyimba byinshi bishoboka hamwe na lymph node hafi, bikurikirwa na chimiotherapie hamwe nubuvuzi bwimirasire.

Rhabdomyosarcoma y'impyiko

• Kubibyimba byimpyiko: Kubaga kugirango ukureho ibibyimba byinshi bishoboka. Imiti ya chimiotherapie hamwe nimirasire irashobora kandi gutangwa.

Rhabdomyosarcoma y'uruhago cyangwa prostate

• Kubibyimba biri hejuru yuruhago gusa: Kubaga (kwaguka kwagutse).

• Kubibyimba bya prostate cyangwa uruhago (usibye hejuru yuruhago):

• Imiti ya chimiotherapie hamwe nimirasire itangwa mbere yo kugabanya ikibyimba. Niba kanseri ya kanseri igumye nyuma ya chimiotherapie no kuvura imirasire, ikibyimba gikurwaho no kubagwa. Kubaga bishobora gukuramo gukuramo prostate, igice cyuruhago, cyangwa pelvic exenteration utiriwe ukuraho urukiramende. .

• Chimiotherapie itangwa mbere kugirango igabanye ikibyimba. Kubaga kugirango bakureho ikibyimba, ariko ntabwo ari uruhago cyangwa prostate, birakorwa. Imiti yo hanze cyangwa hanze irashobora gutangwa nyuma yo kubagwa.

• Kubaga kugirango ukureho ikibyimba, ariko ntabwo ari uruhago cyangwa prostate. Imiti ivura imbere itangwa nyuma yo kubagwa.

Rhabdomyosarcoma yakarere hafi yintangangore

• Kubaga kugirango ukureho intangangabo n'umugongo. Indimu ya lymph inyuma yinda irashobora gusuzumwa kanseri, cyane cyane iyo lymph node nini cyangwa umwana afite imyaka 10 cyangwa irenga.

• Imiti ivura imirasire irashobora gutangwa mugihe ikibyimba kidashobora kuvaho burundu kubagwa.

Rhabdomyosarcoma yigituba, igituba, nyababyeyi, inkondo y'umura, cyangwa intanga ngore

• Kubibyimba byigituba nigituba: Mu kuvura hashobora kuba harimo chimiotherapie ikurikirwa no kubagwa kugirango ikureho ikibyimba. Imiti yo hanze cyangwa hanze irashobora gutangwa nyuma yo kubagwa.

• Kubibyimba byo muri nyababyeyi: Ubuvuzi bushobora kuba bukubiyemo imiti ya chimiotherapie cyangwa idafite imiti ivura imirasire. Rimwe na rimwe, hashobora gukenerwa kubagwa kugira ngo ukureho kanseri zose zisigaye.

• Ku bibyimba by'inkondo y'umura: Mu kuvura hashobora kuba harimo chimiotherapie ikurikirwa no kubagwa kugirango ikureho ikibyimba gisigaye.

• Ku bibyimba by'intanga ngore: Ubuvuzi bushobora kuba bukubiyemo imiti ya chimiotherapie ikurikirwa no kubagwa kugirango ikureho ikibyimba gisigaye.

Metastatike rhabdomyosarcoma

Umuti, nka chimiotherapie, imiti ivura imirasire, cyangwa kubagwa kugirango ukureho ikibyimba, uhabwa aho ikibyimba cyatangiriye. Niba kanseri yarakwirakwiriye mu bwonko, uruti rw'umugongo, cyangwa ibihaha, imiti ivura imirasire ishobora no guhabwa aho kanseri yakwirakwiriye.

Ubuvuzi bukurikira burimo kwigwa kuri rhabdomyosarcoma metastatike:

• Igeragezwa rya clinique yubudahangarwa (kuvura urukingo).

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Kwanga cyangwa Gusubiramo Ubwana Rhabdomyosarcoma

Uburyo bwo kuvura indwara ya rhabdomyosarcoma yo mu bwana cyangwa igaruka kenshi ishingiye ku bintu byinshi, harimo n'aho mu mubiri kanseri yagarukiye, ni ubuhe buryo bwo kuvura umwana yari afite mbere, ndetse n'ibyo umwana akeneye.

Kuvura rhabdomyosarcoma yanga cyangwa igaruka kenshi irashobora kubamo kimwe cyangwa byinshi muribi bikurikira:

• Kubaga.

• Imiti ivura imirasire.

• Chimoterapi.

• Igeragezwa rya clinique yubuvuzi bugenewe cyangwa immunotherapy (sirolimus, ipilimumab, nivolumab, cyangwa pembrolizumab).

• Igeragezwa rya clinique yubuvuzi bugenewe hamwe na tyrosine kinase inhibitor (MK-1775 cyangwa cabozantinib-s-malate) hamwe na chimiotherapie.

• Igeragezwa rya clinique risuzuma icyitegererezo cyibibyimba byumurwayi kugirango hahindurwe gene. Ubwoko bwo kuvura bugenewe umurwayi biterwa n'ubwoko bw'imihindagurikire ya gene.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Kumenya Byinshi Kubana Rhabdomyosarcoma

Ushaka amakuru menshi yikigo cyigihugu cya kanseri kubyerekeye rhabdomyosarcoma yo mu bwana, reba ibi bikurikira:

• Urupapuro rworoshye Sarcoma Urupapuro rwurugo

• Kubara Tomografiya (CT) Gusikana na Kanseri

• Ibiyobyabwenge Byemewe kuri Rhabdomyosarcoma

• Intego zo kuvura Kanseri

Kubindi bisobanuro bya kanseri yo mu bwana hamwe nubundi buryo rusange bwa kanseri, reba ibi bikurikira:

• Ibyerekeye Kanseri

• Kanseri yo mu bwana

• Umuti wo Gushakisha Kanseri Yabana Kureka

• Ingaruka Zitinze Kuvura Kanseri Yabana

• Ingimbi n'abangavu bafite kanseri

• Abana barwaye Kanseri: Imfashanyigisho ku babyeyi

• Kanseri mu bana n'ingimbi

• Gutegura

• Guhangana na Kanseri

• Ibibazo byo Kubaza Muganga wawe kuri Kanseri

• Abacitse ku icumu n'abarezi