Ubwoko / ovarian / umurwayi / ovarian-epithelial-kuvura-pdq

Ovarian Epithelial, Fallopian Tube, hamwe na Kanseri yibanze ya Peritoneyale

Amakuru Rusange Yerekeye Ovarian Epithelial, Fallopian Tube, na Kanseri yibanze ya Peritoneyale

INGINGO Z'INGENZI

• Ovarian epithelial kanseri, kanseri yigituba, na kanseri yibanze ya peritoneyale ni indwara aho ingirabuzimafatizo mbi (kanseri) ziba mu ngingo zifata intanga ngore cyangwa zikaba zifata umuyoboro wa fallopian cyangwa peritoneum.

• Ovarian epithelial kanseri, kanseri yigituba, na kanseri yibanze ya peritoneyale muburyo bumwe bwimitsi kandi bifatwa kimwe.

• Abagore bafite amateka yumuryango wa kanseri yintanga bafite ibyago byinshi byo kurwara kanseri yintanga.

• Indwara ya ovarian, fallopian tube, na kanseri yibanze ya peritoneyale biterwa na mutation ya gene yarazwe (impinduka).

• Abagore bafite ibyago byinshi byo kurwara kanseri yintanga barashobora gutekereza kubagwa kugirango bagabanye ibyago.

• Ibimenyetso nibimenyetso bya ovarian, fallopian tube, cyangwa kanseri ya peritoneal harimo kubabara cyangwa kubyimba munda.

• Ibizamini bisuzuma intanga ngore hamwe na pelvic bikoreshwa mugushakisha (gushakisha), gusuzuma, no gutera intanga ngore, umuyoboro wa fallopian, na kanseri ya peritoneal.

• Ibintu bimwe bigira ingaruka kumahitamo no kuvura (amahirwe yo gukira).

Ovarian epithelial kanseri, kanseri yigituba, na kanseri yibanze ya peritoneyale ni indwara aho ingirabuzimafatizo mbi (kanseri) ziba mu ngingo zifata intanga ngore cyangwa zikaba zifata umuyoboro wa fallopian cyangwa peritoneum.

Intanga ngore ni ingingo ebyiri muri sisitemu yimyororokere yumugore. Biri mu gitereko, kimwe kuri buri ruhande rwa nyababyeyi (urugingo rudakomeye, rumeze nk'isaro aho uruhinja rukurira). Buri ntanga ngore hafi yubunini n'imiterere ya almande. Intanga ngore zikora amagi na hormone zumugore (imiti igenzura uburyo selile cyangwa ingingo zimwe na zimwe zikora).

Imiyoboro ya fallopian ni jambo rirerire, ryoroshye, imwe kuruhande rwa nyababyeyi. Amagi anyura mu ntanga ngore, anyuze mu miyoboro ya fallopian, yerekeza muri nyababyeyi. Kanseri rimwe na rimwe itangirira ku musozo w'igitereko cya fallopian hafi yintanga ngore ikwirakwira.

Peritoneum ni tissue itondekanya urukuta rwinda kandi igapfundikira ingingo zo munda. Kanseri y'ibanze ya peritoneyale ni kanseri igaragara muri peritoneum kandi ntabwo yakwirakwiriye kuva mu kindi gice cy'umubiri. Kanseri rimwe na rimwe itangirira muri peritoneum ikwirakwira muri ovary.

Anatomy ya sisitemu yimyororokere yumugore. Ingingo ziri muri sisitemu yimyororokere yumugore zirimo nyababyeyi, intanga ngore, igituba, inkondo y'umura, nigituba. Inda ifite imitsi yo hanze yitwa myometrium n'umurongo w'imbere witwa endometrium.

Ovarian epithelial kanseri ni ubwoko bumwe bwa kanseri yibasira intanga ngore. Reba incamake yo kuvura ikurikira kugirango umenye amakuru yandi moko y'ibibyimba by'intanga ngore:

• Intanga ngore ya Ovarian

• Ovarian Ntoya Yangiza Ibibyimba

• Kanseri idasanzwe yo kuvura abana (kanseri yintanga ku bana)

Ovarian epithelial kanseri, kanseri yigituba, na kanseri yibanze ya peritoneyale muburyo bumwe bwimitsi kandi bifatwa kimwe.

Abagore bafite amateka yumuryango wa kanseri yintanga bafite ibyago byinshi byo kurwara kanseri yintanga.

Ikintu cyose cyongera amahirwe yo kwandura indwara cyitwa impanuka. Kugira ibintu bishobora guteza ibyago ntibisobanura ko uzarwara kanseri; kutagira ibyago bishobora gusobanura ko utazarwara kanseri. Vugana na muganga wawe niba utekereza ko ushobora guhura na kanseri yintanga.

Impamvu zishobora gutera kanseri yintanga zirimo ibi bikurikira:

• Amateka yumuryango wa kanseri yintanga mubyara wo mucyiciro cya mbere (nyina, umukobwa, cyangwa mushiki wawe).

• Impinduka zarazwe muri gen BRCA1 cyangwa BRCA2.

• Ibindi bihe byo kuragwa, nka kanseri yo mu bwoko bwa hereditaire nonpolypose kanseri (HNPCC; nanone yitwa Lynch syndrome).

• Endometriose.

• Ubuvuzi bwa hormone nyuma yo gucura.

• Umubyibuho ukabije.

• Uburebure burebure.

Ubusaza nimpamvu nyamukuru itera kanseri nyinshi. Amahirwe yo kurwara kanseri ariyongera uko ugenda ukura.

Indwara ya ovarian, fallopian tube, na kanseri yibanze ya peritoneyale biterwa na mutation ya gene yarazwe (impinduka).

Ingirabuzimafatizo ziri mu ngirabuzimafatizo zitwara amakuru akomoka ku babyeyi b'umuntu. Kanseri yintanga ngore igizwe na 20% bya kanseri yintanga. Hariho uburyo butatu bwo kuragwa: kanseri yintanga yonyine, kanseri yintanga namabere, na kanseri yintanga ngore.

Kanseri yo mu bwoko bwa Fallopian na kanseri ya peritoneal nayo ishobora guterwa na mutation zimwe na zimwe yarazwe.

Hariho ibizamini bishobora kumenya ihinduka ryimiterere ya gene. Igeragezwa rya genetike rimwe na rimwe rikorwa kubagize imiryango ifite ibyago byinshi byo kurwara kanseri. Reba incamake ya ikurikira kubindi bisobanuro:

• Ovarian, Fallopian Tube, hamwe no Kurinda Kanseri Yibanze ya Peritoneyale

• Irondakoko rya Kanseri y'ibere na Ginecologic (kubashinzwe ubuzima)

Abagore bafite ibyago byinshi byo kurwara kanseri yintanga barashobora gutekereza kubagwa kugirango bagabanye ibyago.

Bamwe mu bagore bafite ibyago byinshi byo kurwara kanseri yintanga barashobora guhitamo kugira oophorectomy igabanya ibyago (kuvanaho intanga ngore kugirango kanseri idashobora gukura muri bo). Ku bagore bafite ibyago byinshi, ubu buryo bwerekanwe kugabanya cyane ibyago byo kurwara kanseri yintanga. (Reba incamake ya kuri Ovarian, Fallopian Tube, na Primary Peritoneal Kurinda Kanseri kubindi bisobanuro.)

Ibimenyetso nibimenyetso bya ovarian, fallopian tube, cyangwa kanseri ya peritoneal harimo kubabara cyangwa kubyimba munda.

Ovarian, fallopian tube, cyangwa kanseri ya peritoneal ntishobora gutera ibimenyetso cyangwa ibimenyetso hakiri kare. Iyo ibimenyetso cyangwa ibimenyetso bigaragara, kanseri iba itera imbere. Ibimenyetso nibimenyetso bishobora kubamo ibi bikurikira:

• Kubabara, kubyimba, cyangwa kumva igitutu munda cyangwa munda.

• Kuva amaraso mu gitsina biremereye cyangwa bidasanzwe, cyane cyane nyuma yo gucura.

• Gusohora mu gitsina bisobanutse, byera, cyangwa bifite amabara y'amaraso.

• Ikibyimba mu gice cya pelvic.

• Ibibazo byo munda, nka gaze, kubyimba, cyangwa kuribwa mu nda.

Ibi bimenyetso nibimenyetso birashobora kandi guterwa nibindi bihe ntabwo biterwa na ovarian, tube fallopian, cyangwa kanseri ya peritoneal. Niba ibimenyetso cyangwa ibimenyetso byarushijeho kuba bibi cyangwa bitagiyeho wenyine, baza muganga wawe kugirango ikibazo icyo ari cyo cyose gisuzumwe kandi kivurwe hakiri kare.

Ibizamini bisuzuma intanga ngore hamwe na pelvic bikoreshwa mugushakisha (gushakisha), gusuzuma, no gutera intanga ngore, umuyoboro wa fallopian, na kanseri ya peritoneal.

Ibizamini hamwe nuburyo bukurikira birashobora gukoreshwa mugushakisha, gusuzuma, no gutera intanga ngore, umuyoboro wa fallopian, na kanseri ya peritoneal:

• Ikizamini cyumubiri namateka: Ikizamini cyumubiri kugirango ugenzure ibimenyetso rusange byubuzima, harimo no gusuzuma ibimenyetso byindwara, nkibibyimba cyangwa ikindi kintu cyose gisa nkidasanzwe. Hazafatwa kandi amateka yubuzima bwumurwayi nindwara zashize hamwe nubuvuzi.

• Ikizamini cya pelvic: Ikizamini cyigituba, inkondo y'umura, nyababyeyi, igituba cya fallopian, ovaries, na rectum. Igitekerezo cyinjijwe mu gitsina kandi umuganga cyangwa umuforomo areba mu gitsina na nyababyeyi kugira ngo agaragaze ibimenyetso byindwara. Ikizamini cya Papi yinkondo y'umura gikunze gukorwa. Muganga cyangwa umuforomo kandi yinjiza intoki imwe cyangwa ebyiri zasizwe, zometse ku ntoki z'ukuboko kumwe mu gitsina hanyuma agashyira ikindi kiganza hejuru yinda yo hepfo kugirango yumve ubunini, imiterere, n'umwanya wa nyababyeyi na ovaire. Muganga cyangwa umuforomo nawe ashyiramo urutoki rwamavuta, rwuzuye urukiramende kugirango yumve ibibyimba cyangwa ahantu hadasanzwe.

Ikizamini cya pelvic. Umuganga cyangwa umuforomo ashyiramo intoki imwe cyangwa ebyiri zasizwe, zuzuye intoki z'ukuboko kumwe mu gitsina hanyuma agakanda ku nda yo hepfo n'ukundi kuboko. Ibi bikorwa kugirango wumve ubunini, imiterere, n'umwanya wa nyababyeyi na ovaries. Igituba, inkondo y'umura, imiyoboro ya fallopian, na rectum nabyo birasuzumwa.

• CA 125 isuzuma: Ikizamini gipima urwego rwa CA 125 mumaraso. CA 125 ni ikintu cyarekuwe na selile mumaraso. Urwego rwa CA 125 rwiyongereye rushobora kuba ikimenyetso cya kanseri cyangwa ikindi kibazo nka endometriose.

• Ikizamini cya Ultrasound: Uburyo bukoreshwa mu majwi y’amajwi menshi (ultrasound) asohoka mu ngingo zo mu nda cyangwa mu nda, hanyuma agasubiramo. Ijwi ryerekana ishusho yumubiri wumubiri witwa sonogram. Ishusho irashobora gucapurwa kugirango irebe nyuma.

Ultrasound yo munda. Transducer ya ultrasound ihujwe na mudasobwa inyuzwa hejuru yinda. Ultrasound transducer isubiza amajwi hejuru yingingo zimbere ninyuma kugirango ikore echo ikora sonogramu (ishusho ya mudasobwa).

Bamwe mu barwayi barashobora kugira ultrasound transvaginal.

Ultrasound ya Transvaginal. Ultrasound probe ihujwe na mudasobwa yinjizwa mu gitsina kandi yimurwa yitonze kugirango yerekane ingingo zitandukanye. Iperereza ryerekana amajwi yumubiri imbere ninyuma kugirango bikore echo ikora sonogramu (ishusho ya mudasobwa).

• CT scan (CAT scan): Uburyo bukora urukurikirane rwamashusho arambuye yibice byimbere mumubiri, byafashwe muburyo butandukanye. Amashusho yakozwe na mudasobwa ihujwe na mashini ya x-ray. Irangi rishobora guterwa mumitsi cyangwa kumirwa kugirango bifashe ingingo cyangwa ingirangingo kugaragara neza. Ubu buryo nabwo bwitwa computing tomografiya, tomografiya ya mudasobwa, cyangwa mudasobwa ya axial tomografiya.

• PET scan (positron emission tomografi scan): Uburyo bwo kubona selile mbi yibibyimba mumubiri. Umubare muto cyane wa glucose ikora radio (isukari) yatewe mumitsi. PET scaneri izenguruka umubiri kandi ikora ishusho yerekana aho glucose ikoreshwa mumubiri. Utugingo ngengabuzima twibibyimba twerekana neza cyane ku ishusho kuko zikora cyane kandi zifata glucose nyinshi kuruta selile zisanzwe.

• MRI . Ubu buryo bwitwa kandi magnetic magnetic resonance imaging (NMRI).

• Isanduku x-ray: X-ray yingingo namagufwa imbere yigituza. X-ray ni ubwoko bwingufu zishobora kunyura mumubiri no kuri firime, bigakora ishusho yibice byumubiri.

• Biopsy: Gukuraho ingirabuzimafatizo cyangwa ingirangingo kugirango zishobore kurebwa munsi ya microscope na patologue kugirango barebe ibimenyetso bya kanseri. Ubusanzwe tissue ikurwaho mugihe cyo kubagwa kugirango ikureho ikibyimba.

• Ibintu bimwe bigira ingaruka kumahitamo no kuvura (amahirwe yo gukira).

Kumenyekanisha (amahirwe yo gukira) hamwe nuburyo bwo kuvura biterwa nibi bikurikira:

• Ubwoko bwa kanseri yintanga nuburyo kanseri ihari.

• Icyiciro n'icyiciro cya kanseri.

• Niba umurwayi afite amazi yinyongera munda atera kubyimba.

• Niba ibibyimba byose bishobora gukurwaho no kubagwa.

• Niba hari impinduka muri gen BRCA1 cyangwa BRCA2.

• Imyaka yumurwayi nubuzima rusange.

• Niba kanseri imaze gupimwa cyangwa yagarutse (garuka).

Icyiciro cya Ovarian Epithelial, Tube ya Fallopiya, na Kanseri yibanze ya Peritoneyale

INGINGO Z'INGENZI

• Nyuma yo gupimwa intanga ngore, fallopian, cyangwa kanseri ya peritoneyale, hakorwa ibizamini kugirango hamenyekane niba kanseri ya kanseri yakwirakwiriye mu ntanga ngore cyangwa mu bindi bice by'umubiri.

• Hariho uburyo butatu kanseri ikwirakwira mu mubiri.

• Kanseri irashobora gukwirakwira aho yatangiriye no mu bindi bice byumubiri.

• Ibyiciro bikurikira bikoreshwa kuri ovarian epithelial, tube fallopian, na kanseri yibanze ya peritoneal:

• Icyiciro I.

• Icyiciro cya II

• Icyiciro cya III

• Icyiciro cya IV

• Ovarian epithelial, tube fallopian, na kanseri yibanze ya peritoneyale bishyizwe hamwe kugirango bivurwe nka kanseri hakiri kare cyangwa yateye imbere.

Nyuma yo gupimwa intanga ngore, fallopian, cyangwa kanseri ya peritoneyale, hakorwa ibizamini kugirango hamenyekane niba kanseri ya kanseri yakwirakwiriye mu ntanga ngore cyangwa mu bindi bice by'umubiri.

Inzira ikoreshwa mu kumenya niba kanseri yarakwirakwiriye mu ngingo cyangwa mu bindi bice by'umubiri byitwa guterana. Amakuru yakusanyirijwe mubikorwa byateguwe agena icyiciro cyindwara. Ni ngombwa kumenya icyiciro kugirango utegure kuvura. Ibisubizo by'ibizamini bikoreshwa mu gusuzuma kanseri akenshi bikoreshwa no gutera indwara. (Reba igice rusange cyamakuru kubizamini nuburyo bukoreshwa mugupima no gutera intanga ngore, umuyoboro wa fallopian, na kanseri ya peritoneal.)

Hariho uburyo butatu kanseri ikwirakwira mu mubiri.

Kanseri irashobora gukwirakwira binyuze mu ngingo, sisitemu ya lymph, n'amaraso:

• Tissue. Kanseri ikwirakwira aho yatangiriye ikurira mu turere twegereye.

• Sisitemu ya Lymph. Kanseri ikwirakwira aho yatangiriye yinjira muri sisitemu ya lymph. Kanseri inyura mu mitsi ya lymph igana mu bindi bice by'umubiri.

• Amaraso. Kanseri ikwirakwira aho yatangiriye yinjira mu maraso. Kanseri inyura mu mitsi y'amaraso igana mu bindi bice by'umubiri.

Kanseri irashobora gukwirakwira aho yatangiriye no mu bindi bice byumubiri.

Iyo kanseri ikwirakwira mu kindi gice cy'umubiri, yitwa metastasis. Ingirabuzimafatizo za kanseri zitandukana aho zatangiriye (ikibyimba kibanza) zikanyura muri sisitemu ya lymph cyangwa maraso.

• Sisitemu ya Lymph. Kanseri yinjira muri sisitemu ya lymph, ikanyura mu mitsi ya lymph, igakora ikibyimba (ikibyimba metastatike) mu kindi gice cy'umubiri.

• Amaraso. Kanseri yinjira mu maraso, ikanyura mu mitsi y'amaraso, igakora ikibyimba (ikibyimba metastatike) mu kindi gice cy'umubiri.

Ikibyimba metastatike nubwoko bumwe bwa kanseri nkibibyimba byibanze. Kurugero, niba kanseri yintanga ngore ikwirakwira mu bihaha, kanseri ya kanseri mu bihaha ni selile ovarian epithelial kanseri. Indwara ni kanseri yintanga ngore, ntabwo ari kanseri y'ibihaha.

Ibyiciro bikurikira bikoreshwa kuri ovarian epithelial, tube fallopian, na kanseri yibanze ya peritoneal:

Icyiciro I.

Mu cyiciro cya IA, kanseri iboneka imbere mu muyoboro umwe w'intanga ngore. Mu cyiciro cya IB, kanseri iboneka imbere yintanga zombi cyangwa igituba. Mu cyiciro cya IC, kanseri iboneka imbere yintanga imwe cyangwa zombi cyangwa igituba cya fallopian kandi kimwe muribi bikurikira ni ukuri: (a) capsule (igipfundikizo cyo hanze) yintanga yaracitse, (b) kanseri nayo iboneka hejuru yinyuma intanga imwe cyangwa zombi cyangwa igituba cya fallopian, cyangwa (c) kanseri ya kanseri iboneka muri pelvic peritoneum.

Mu cyiciro cya I, kanseri iboneka muri ovaire imwe cyangwa zombi cyangwa igituba cya fallopian. Icyiciro cya I kigabanijwe mu cyiciro cya IA, icyiciro cya IB, na IC.

• Icyiciro cya IA: Kanseri iboneka imbere yintanga imwe cyangwa igituba.

• Icyiciro cya IB: Kanseri iboneka imbere yintanga ngore cyangwa igituba.

• Icyiciro IC: Kanseri iboneka imbere yintanga imwe cyangwa zombi cyangwa igituba cya fallopian kandi kimwe muribi gikurikira nukuri:

• kanseri iboneka no hejuru yinyuma imwe cyangwa intanga ngore cyangwa igituba; cyangwa

• capsule (igipfundikizo cyo hanze) cy'intanga ngore yacitse (yamenetse) mbere cyangwa mugihe cyo kubagwa; cyangwa

• selile ya kanseri iboneka mumazi ya cavit peritoneal (cavit yumubiri irimo ingingo nyinshi ziri munda) cyangwa mukwoza peritoneum (tissue iri mumyanya ya peritoneal).

Icyiciro cya II

Mu cyiciro cya IIA, kanseri iboneka muri imwe cyangwa zombi cyangwa intanga ngore kandi ikwirakwira muri nyababyeyi na / cyangwa igituba na / cyangwa intanga ngore. Mu cyiciro cya IIB, kanseri iboneka muri ovaire imwe cyangwa zombi cyangwa mu miyoboro ya fallopian kandi ikwirakwira mu mara. Muri kanseri y'ibanze ya kanseri, kanseri iboneka muri pelvic peritoneum kandi ntabwo yakwirakwiriye kuva mu kindi gice cy'umubiri.

Mu cyiciro cya II, kanseri iboneka muri ovaire imwe cyangwa zombi cyangwa mu miyoboro ya fallopian kandi ikwirakwira mu tundi turere twa pelvis, cyangwa kanseri y'ibanze ya peritoneal iboneka mu gitereko. Icyiciro cya II ovarian epithelial na fallopian kanseri ya kanseri igabanijwemo icyiciro cya IIA nicyiciro cya IIB.

• Icyiciro cya IIA: Kanseri yakwirakwiriye kuva aho yatangiriye bwa mbere muri nyababyeyi na / cyangwa imiyoboro ya fallopian na / cyangwa intanga ngore.

• Icyiciro cya IIB: Kanseri yakwirakwiriye mu muyoboro w'intanga ngore cyangwa mu mitsi kugeza mu ngingo ziri mu cyuho cya peritoneyale (umwanya urimo ingingo zo mu nda).

Ingano ya Tumor ikunze gupimwa muri santimetero (cm) cyangwa santimetero. Ibiribwa bisanzwe bishobora gukoreshwa mu kwerekana ubunini bwikibyimba muri cm harimo: amashaza (cm 1), ibishyimbo (cm 2), umuzabibu (cm 3), walnut (cm 4), lime (cm 5 cyangwa 2 santimetero), igi (cm 6), amashaza (cm 7), n'imbuto (cm 10 cyangwa santimetero 4).

Icyiciro cya III

Mu cyiciro cya III, kanseri iboneka muri ovaire imwe cyangwa zombi cyangwa mu miyoboro ya fallopian, cyangwa ni kanseri y'ibanze ya peritoneyale, kandi ikwirakwira hanze yigitereko kugera mu bindi bice byinda ndetse na / cyangwa hafi ya lymph node. Icyiciro cya III kigabanijwe mu cyiciro cya IIIA, icyiciro cya IIIB, n'icyiciro cya IIIC.

• Mu cyiciro cya IIIA, kimwe muri ibi bikurikira ni ukuri:

• Kanseri yakwirakwiriye kuri lymph node mu gice cyo hanze cyangwa inyuma ya peritoneum gusa; cyangwa

• Ingirabuzimafatizo za kanseri zishobora kugaragara gusa hamwe na microscope zimaze gukwirakwira hejuru ya peritoneum hanze yigitereko. Kanseri irashobora gukwirakwira hafi ya lymph node.

Mu cyiciro cya IIIA, kanseri iboneka muri ovaire imwe cyangwa zombi cyangwa mu miyoboro ya fallopian kandi (a) kanseri yakwirakwiriye mu mitsi ya lymph mu gice cyo hanze cyangwa inyuma ya peritoneum gusa, cyangwa (b) kanseri ya kanseri ishobora kugaragara gusa na microscope ifite gukwirakwira kuri omentum. Kanseri irashobora gukwirakwira hafi ya lymph node.

• Icyiciro cya IIIB: Kanseri yakwirakwiriye kuri peritoneum hanze yigitereko kandi kanseri yo muri peritoneum ni santimetero 2 cyangwa nto. Kanseri irashobora gukwirakwira kuri lymph node inyuma ya peritoneum.

Mu cyiciro cya IIIB, kanseri iboneka muri ovaire imwe cyangwa zombi cyangwa mu miyoboro ya fallopian kandi ikwirakwira kuri omentum, kandi kanseri yo muri omentum ni santimetero 2 cyangwa nto. Kanseri irashobora gukwirakwira kuri lymph node inyuma ya peritoneum.

• Icyiciro cya IIIC: Kanseri yakwirakwiriye kuri peritoneum hanze yigitereko kandi kanseri yo muri peritone iri hejuru ya santimetero 2. Kanseri irashobora gukwirakwira kuri lymph node inyuma ya peritoneum cyangwa hejuru yumwijima cyangwa ururenda.

Mu cyiciro cya IIIC, kanseri iboneka muri ovaire imwe cyangwa zombi cyangwa mu miyoboro ya fallopian kandi ikwirakwira kuri omentum, kandi kanseri yo muri omentum irenze santimetero 2. Kanseri irashobora gukwirakwira kuri lymph node inyuma ya peritoneum cyangwa hejuru yumwijima cyangwa ururenda.

Icyiciro cya IV

Mu cyiciro cya IV, kanseri yakwirakwiriye mu nda kugera mu bindi bice by'umubiri. Mu cyiciro cya IVA, selile ya kanseri iboneka mumazi yinyongera yubaka ibihaha. Mu cyiciro cya IVB, kanseri yakwirakwiriye mu ngingo no mu ngingo hanze y’inda, harimo ibihaha, umwijima, amagufwa, na lymph node mu kibero.

Mu cyiciro cya IV, kanseri yakwirakwiriye mu nda kugera mu bindi bice by'umubiri. Icyiciro cya IV kigabanijwe mu cyiciro cya IVA n'icyiciro cya IVB.

• Icyiciro cya IVA: Ingirabuzimafatizo za kanseri ziboneka mumazi yinyongera yubaka ibihaha.

• Icyiciro cya IVB: Kanseri yakwirakwiriye mu ngingo no mu ngingo hanze yinda, harimo na lymph node mu kibero.

Ovarian epithelial, tube fallopian, na kanseri yibanze ya peritoneyale bishyizwe hamwe kugirango bivurwe nka kanseri hakiri kare cyangwa yateye imbere.

Icyiciro cya I ovarian epithelial na fallopian tube kanseri ifatwa nka kanseri hakiri kare.

Icyiciro cya II, III, na IV ovarian epithelial, tube fallopian, na kanseri yibanze ya peritoneal ifatwa nka kanseri yateye imbere.

Epitheliyale Yisubiramo cyangwa Ihoraho, Tube ya Fallopiya, na Kanseri yibanze ya Peritoneyale

Indwara ya ovarian epithelial kanseri, kanseri yigituba ya kanseri, cyangwa kanseri yibanze ya peritoneal ni kanseri yagarutse (garuka) imaze kuvurwa. Kanseri idahoraho ni kanseri itajyana no kuvurwa.

Incamake yo kuvura

INGINGO Z'INGENZI

• Hariho uburyo butandukanye bwo kuvura abarwayi bafite kanseri yintanga ngore.

• Ubwoko butatu bwo kuvura bukoreshwa.

• Kubaga

• Chimoterapi

• Ubuvuzi bugamije

• Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.

• Imiti ivura imirasire

• Immunotherapy

• Kuvura intanga ngore, umuyoboro wa fallopian, na kanseri y'ibanze ya peritoneyale bishobora gutera ingaruka.

• Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.

• Abarwayi barashobora kwipimisha kwa muganga mbere, mugihe, cyangwa nyuma yo gutangira kuvura kanseri.

• Ibizamini byo gukurikirana birashobora gukenerwa.

Hariho uburyo butandukanye bwo kuvura abarwayi bafite kanseri yintanga ngore.

Ubwoko butandukanye bwo kuvura burahari kubarwayi barwaye kanseri yintanga. Bumwe mu buvuzi busanzwe, kandi bumwe burimo kugeragezwa mubigeragezo byamavuriro. Ikigeragezo kivura ni ubushakashatsi bwakozwe bugamije gufasha kunoza imiti igezweho cyangwa kubona amakuru ku buvuzi bushya ku barwayi ba kanseri. Iyo ibizamini byamavuriro byerekana ko ubuvuzi bushya buruta ubuvuzi bukoreshwa nkubuvuzi busanzwe, ubuvuzi bushya bushobora kuba ubuvuzi busanzwe. Abarwayi bafite kanseri iyo ari yo yose ya kanseri yintanga barashobora gushaka gutekereza kubijyanye no kwipimisha kwa muganga. Ibigeragezo bimwe na bimwe bivura abarwayi batatangiye kwivuza.

Ubwoko butatu bwo kuvura bukoreshwa.

Kubaga

Abarwayi benshi barabazwe kugirango bakureho ikibyimba kinini gishoboka. Ubwoko butandukanye bwo kubaga bushobora kubamo:

• Hysterectomy: Kubaga gukuramo nyababyeyi, rimwe na rimwe, inkondo y'umura. Iyo nyababyeyi ikuweho gusa, yitwa hysterectomy igice. Iyo nyababyeyi na nyababyeyi byombi bivanyweho, byitwa hysterectomy. Niba nyababyeyi na nyababyeyi bikuwe mu gitsina, kubaga byitwa hysterectomy. Niba nyababyeyi na nyababyeyi bisohotse binyuze mu nda nini (gukata) mu nda, kubaga byitwa hysterectomy yo munda yuzuye. Niba nyababyeyi na nyababyeyi bisohotse hifashishijwe agace gato (gukata) mu nda ukoresheje laparoskopi, kubaga bita laparoscopique hysterectomy.

Hysterectomy. Inda ikurwaho kubagwa cyangwa idafite izindi ngingo cyangwa ingirangingo. Muri hysterectomy yuzuye, nyababyeyi na nyababyeyi bikurwaho. Muri hysterectomy yuzuye hamwe na salpingo-oophorectomy, (a) nyababyeyi hiyongereyeho intanga ngore imwe (unilateral) ovary na fallopian; cyangwa (b) nyababyeyi hiyongereyeho intanga zombi (zombi) hamwe na tebes zo mu bwoko bwa fallopian. Muri hysterectomy ikabije, nyababyeyi, inkondo y'umura, intanga zombi, imiyoboro yombi, hamwe na tissue hafi. Ubu buryo bukorwa hifashishijwe uburyo buke bwo guhinduranya cyangwa guhagarikwa.

• Salpingo-oophorectomy itabogamye: Uburyo bwo kubaga kugirango ukureho intanga imwe n'umuyoboro umwe.

• Impande zombi salpingo-oophorectomy: Uburyo bwo kubaga kugirango ukuremo intanga ngore zombi.

• Omentectomy: Uburyo bwo kubaga kugirango ukureho omentum (tissue muri peritoneum irimo imiyoboro y'amaraso, imitsi, imiyoboro ya lymph, na lymph node).

• Lymph node biopsy: Gukuraho ibintu byose cyangwa igice cya lymph node. Inzobere mu bijyanye n’indwara ireba lymph node tissue munsi ya microscope kugirango isuzume selile.

Chimoterapi

Chimoterapi ni umuti wa kanseri ukoresha ibiyobyabwenge kugirango uhagarike imikurire ya kanseri, haba mu kwica selile cyangwa kubabuza gutandukana. Iyo chimiotherapie ifashwe numunwa cyangwa igaterwa mumitsi cyangwa imitsi, imiti yinjira mumaraso kandi irashobora kugera kanseri ya kanseri mumubiri (chimiotherapie sisitemu). Iyo chimiotherapie ishyizwe mumazi yubwonko, urugingo, cyangwa umwobo wumubiri nkinda, imiti yibasira kanseri ya kanseri muri utwo turere (chimiotherapie yo mukarere).

Ubwoko bwa chimiotherapie yo mukarere ikoreshwa mukuvura kanseri yintanga ni intraperitoneal (IP) chimiotherapie. Muri IP chimiotherapie, imiti igabanya ubukana ijyanwa mu cyuho cya peritoneyale (umwanya urimo ingingo zo mu nda) binyuze mu muyoboro muto.

Hyperthermic intraperitoneal chimiotherapie (HIPEC) nubuvuzi bukoreshwa mugihe cyo kubagwa burimo kwigwa kuri kanseri yintanga. Nyuma yo kubaga amaze gukuramo ibibyimba byinshi bishoboka, imiti ivura imiti yoherejwe mu cyuho cya peritoneyale.

Umuti hamwe numuti urenze umwe anticancer witwa chimiotherapie.

Uburyo chimiotherapie itangwa biterwa nubwoko nicyiciro cya kanseri ivurwa.

Reba Ibiyobyabwenge Byemewe kuri Ovarian, Fallopian Tube, cyangwa Kanseri Yibanze ya Peritoneyale kubindi bisobanuro.

Ubuvuzi bugamije

Ubuvuzi bugamije ni uburyo bwo kuvura bukoresha ibiyobyabwenge cyangwa ibindi bintu kugirango umenye kandi utere kanseri yihariye ya kanseri utangiza ingirabuzimafatizo zisanzwe.

Ubuvuzi bwa antibody ya Monoclonal ni ubwoko bwubuvuzi bugamije gukoresha antibodies zakozwe muri laboratoire, uhereye mubwoko bumwe bwimikorere ya selile. Iyi antibodies irashobora kumenya ibintu biri muri kanseri ya kanseri cyangwa ibintu bisanzwe bishobora gufasha kanseri gukura. Antibodiyite ifata ibintu kandi ikica selile ya kanseri, ikabuza gukura kwayo, cyangwa ikabuza gukwirakwira. Antibodiyite za Monoclonal zitangwa no gushiramo. Bashobora gukoreshwa bonyine cyangwa gutwara ibiyobyabwenge, uburozi, cyangwa ibikoresho bya radio bikoresha kanseri ya kanseri.

Bevacizumab ni antibody ya monoclonal ishobora gukoreshwa hamwe na chimiotherapie mu kuvura kanseri y'intanga ngore, kanseri yo mu mitsi, cyangwa kanseri y'ibanze ya peritoneyale yagarutse (garuka).

Polyitori (ADP-ribose) polymerase inhibitori (PARP inhibitor) ni imiti ivura imiti ibuza gusana ADN kandi ishobora gutera kanseri ya kanseri. Olaparib, rucaparib, na niraparib ni inzitizi za PARP zishobora gukoreshwa mu kuvura kanseri yintanga ngore. Rucaparib irashobora kandi gukoreshwa nkubuvuzi bwo kuvura kanseri yintanga ngore, kanseri yigituba, cyangwa kanseri yibanze ya peritoneyale yagarutse. Veliparib ni inhibitori ya PARP irimo kwigwa kuvura kanseri yintanga.

Indwara ya Angiogenez ni imiti igabanya ubukana ishobora gukumira imikurire mishya y'amaraso ibibyimba bigomba gukura kandi bishobora kwica selile. Cediranib ni inhibitori ya angiogenez yiga mu kuvura kanseri yintanga ngore.

Reba Ibiyobyabwenge Byemewe kuri Ovarian, Fallopian Tube, cyangwa Kanseri Yibanze ya Peritoneyale kubindi bisobanuro.

Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.

Iki gice cyincamake gisobanura imiti irimo kwigwa mubigeragezo byamavuriro. Ntishobora kuvuga ubuvuzi bushya burimo kwigwa. Amakuru yerekeye ibizamini byamavuriro araboneka kurubuga rwa NCI.

Imiti ivura imirasire

Imishwarara ivura ni imiti ikoresha kanseri ikoresha ingufu nyinshi za x-imirasire cyangwa ubundi bwoko bwimirasire yica kanseri cyangwa ikabuza gukura. Bamwe mu bagore bahabwa ubuvuzi bwitwa intraperitoneal radiation therapy, aho amazi ya radiyo ashyirwa mu nda binyuze muri catheter. Ubuvuzi bwa Intraperitoneal burimo kwigwa kuvura kanseri yintanga.

Immunotherapy

Immunotherapy nubuvuzi bukoresha sisitemu yumubiri yumurwayi kurwanya kanseri. Ibintu bikozwe numubiri cyangwa bikozwe muri laboratoire bikoreshwa mukuzamura, kuyobora, cyangwa kugarura umubiri kamere irinda kanseri. Ubu bwoko bwo kuvura kanseri nabwo bwitwa biotherapy cyangwa immunotherapy.

Ubuvuzi bwinkingo nubuvuzi bwa kanseri bukoresha ibintu cyangwa itsinda ryibintu kugirango bikangure sisitemu yumubiri kugirango ibone ikibyimba ikice. Ubuvuzi bwinkingo burimo kwigwa kugirango bivure kanseri yintanga yateye imbere.

Kuvura intanga ngore, umuyoboro wa fallopian, na kanseri y'ibanze ya peritoneyale bishobora gutera ingaruka.

Kumakuru yingaruka ziterwa no kuvura kanseri, reba urupapuro rwuruhande rwacu.

Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.

Ku barwayi bamwe, kwitabira ikizamini cyamavuriro birashobora kuba uburyo bwiza bwo kuvura. Ibigeragezo bivura biri mubikorwa byubushakashatsi bwa kanseri. Igeragezwa rya Clinical rikorwa kugirango hamenyekane niba imiti mishya ya kanseri itekanye kandi ifite akamaro cyangwa nziza kuruta ubuvuzi busanzwe.

Benshi mubuvuzi busanzwe bwa kanseri bushingiye kubigeragezo byambere byubuvuzi. Abarwayi bitabiriye kwipimisha barashobora kuvurwa bisanzwe cyangwa kuba mubambere bahawe imiti mishya.

Abarwayi bitabira ibizamini byo kwa muganga nabo bafasha kunoza uburyo kanseri izavurwa mugihe kizaza. Nubwo ibigeragezo bivura bitaganisha ku buvuzi bushya, akenshi basubiza ibibazo byingenzi kandi bigafasha gutera imbere ubushakashatsi.

Abarwayi barashobora kwipimisha kwa muganga mbere, mugihe, cyangwa nyuma yo gutangira kuvura kanseri.

Igeragezwa rimwe na rimwe ririmo abarwayi bataravurwa. Ibindi bigeragezo bipima abarwayi bafite kanseri itameze neza. Hariho kandi ibizamini byo kwa muganga bipima uburyo bushya bwo guhagarika kanseri kongera kugaruka (kugaruka) cyangwa kugabanya ingaruka zo kuvura kanseri.

Igeragezwa rya Clinical ririmo kubera mu bice byinshi by'igihugu. Amakuru yerekeye ibizamini byamavuriro ashyigikiwe na NCI urashobora kubisanga kurubuga rwa NCI. Ibizamini bya Clinical bishyigikiwe nandi mashyirahamwe murashobora kubisanga kurubuga rwa ClinicalTrials.gov.

Ibizamini byo gukurikirana birashobora gukenerwa.

Bimwe mubizamini byakozwe mugupima kanseri cyangwa kumenya icyiciro cya kanseri birashobora gusubirwamo. Ibizamini bimwe bizasubirwamo kugirango harebwe uburyo ubuvuzi bukora neza. Ibyemezo bijyanye no gukomeza, guhindura, cyangwa guhagarika ubuvuzi birashobora gushingira kubisubizo byibi bizamini.

Bimwe mubizamini bizakomeza gukorwa buri gihe nyuma yubuvuzi burangiye. Ibisubizo by'ibi bizamini birashobora kwerekana niba ubuzima bwawe bwarahindutse cyangwa niba kanseri yarongeye (garuka). Ibi bizamini rimwe na rimwe byitwa gukurikirana-ibizamini cyangwa kugenzura.

Amahitamo yo Kuvura Icyiciro

Muri iki gice

• Indwara ya Ovarian Epithelial na Fallopian Tube Kanseri

• Indwara ya Ovarian Epithelial, Tube Fallopian, na Kanseri yibanze ya Peritoneyale

Kumakuru yerekeye imiti yavuzwe hepfo, reba igice cyo kuvura.

Indwara ya Ovarian Epithelial na Fallopian Tube Kanseri

Kuvura kanseri yintanga ngore ya kanseri cyangwa kanseri yigituba ishobora kuba ikubiyemo ibi bikurikira:

• Hysterectomy, salpingo-oophorectomy, na omentectomy. Lymph node hamwe nizindi ngingo zo munda no munda zivanwaho kandi zigasuzumwa munsi ya microscope ya selile kanseri. Chimiotherapie irashobora gutangwa nyuma yo kubagwa.

• Salpingo-oophorectomy imwe irashobora gukorwa mubagore bamwe bifuza kubyara. Chimoterapi irashobora gutangwa nyuma yo kubagwa.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Indwara ya Ovarian Epithelial, Tube Fallopian, na Kanseri yibanze ya Peritoneyale

Kuvura kanseri yintanga yintanga ya kanseri, kanseri yigituba, cyangwa kanseri yibanze ya peritoneal irashobora kuba ikubiyemo ibi bikurikira:

• Hysterectomy, salpingo-oophorectomy, na omentectomy. Indimu ya Lymph hamwe nizindi ngingo zo munda no munda zivanwaho kandi zigasuzumwa munsi ya microscope kugirango zishakire kanseri. Kubaga bikurikirwa na kimwe muri ibi bikurikira:

• Imiti ivura imiti.

• Imiti ya chimiotherapie.

• Chimiotherapie hamwe nubuvuzi bugamije (bevacizumab).

• Chimoterapi hamwe nubuvuzi bugamije hamwe na poly (ADP-ribose) polymerase (PARP) inhibitor.

• Chimiotherapie ikurikirwa no kubagwa (birashoboka ko ikurikirwa na chimiotherapie intraperitoneal).

• Chimiotherapie yonyine kubarwayi badashobora kubagwa.

• Igeragezwa rya clinique yubuvuzi bugamije hamwe na PARP inhibitor (olaparib, rucaparib, niraparib, cyangwa veliparib).

• Igeragezwa rya clinique ya hyperthermic intraperitoneal chimiotherapie (HIPEC) mugihe cyo kubagwa.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Amahitamo yo Kuvura Epithelia Yisubiramo cyangwa Ihoraho, Tube Fallopian, na Kanseri Yibanze ya Peritoneyale

Kumakuru yerekeye imiti yavuzwe hepfo, reba igice cyo kuvura.

Kuvura kanseri yintanga ngore, kanseri yigituba, cyangwa kanseri yibanze ya peritoneal irashobora kuba ikubiyemo ibi bikurikira:

• Chimiotherapie ukoresheje imiti imwe cyangwa myinshi ya anticancer.

• Ubuvuzi bugamije hamwe na polymerase (ADP-ribose) polymerase (PARP) inhibitor (olaparib, rucaparib, niraparib, cyangwa cediranib) hamwe na chimiotherapie cyangwa idafite.

• Chimoterapi na / cyangwa igamije kuvura (bevacizumab).

• Igeragezwa rya clinique ya hyperthermic intraperitoneal chimiotherapie (HIPEC) mugihe cyo kubagwa.

• Ikigeragezo cyamavuriro yubuvuzi bushya.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Kugira ngo umenye byinshi kuri Ovarian Epithelial, Tube ya Fallopiya, na Kanseri yibanze ya Peritoneyale

Ushaka amakuru menshi yikigo cyigihugu cya kanseri kubyerekeye ovarian epithelial, tube fallopian, na kanseri yibanze ya peritoneal, reba ibi bikurikira:

• Ovarian, Fallopian Tube, na Primaire ya Kanseri Yibanze Urupapuro

• Ovarian, Fallopian Tube, hamwe no Kurinda Kanseri Yibanze ya Peritoneyale

• Ovarian, Fallopian Tube, hamwe na Kanseri Yibanze ya Peritoneyale

• Kanseri idasanzwe yo kuvura abana

• Ibiyobyabwenge Byemewe kuri Ovarian, Fallopian Tube, cyangwa Kanseri yibanze ya Peritoneyale

• Intego zo kuvura Kanseri

• Guhinduka kwa BRCA: Ibyago bya Kanseri no Kwipimisha

• Kwipimisha genetike ya Syndromes Yarazwe Kanseri

Kumakuru rusange ya kanseri nibindi bikoresho biva mu kigo cyigihugu cya kanseri, reba ibi bikurikira:

• Ibyerekeye Kanseri

• Gutegura

• Chimiotherapie nawe: Inkunga kubantu barwaye Kanseri

• Ubuvuzi bwimirasire nawe: Inkunga kubantu barwaye Kanseri

• Guhangana na Kanseri

• Ibibazo byo Kubaza Muganga wawe kuri Kanseri

• Abacitse ku icumu n'abarezi