Types/myeloproliferative/patient/myelodysplastic-treatment-pdq

Indwara ya Myelodysplastic Syndromes (®) - Indwara y'abarwayi

Amakuru Rusange Yerekeye Syndromes ya Myelodysplastic

INGINGO Z'INGENZI

• Syndromes ya Myelodysplastic ni itsinda rya kanseri aho uturemangingo twamaraso tudakuze mumitsi yamagufwa adakura cyangwa ngo ahinduke selile nziza.

• Ubwoko butandukanye bwa syndromes ya myelodysplastic isuzumwa hashingiwe ku mpinduka zimwe na zimwe ziba mu maraso no mu magufa.

• Imyaka hamwe nubuvuzi bwa kera hamwe na chimiotherapie cyangwa imiti ivura imirasire bigira ingaruka kumyanya myelodysplastic syndrome.

• Ibimenyetso nibimenyetso bya syndrome ya myelodysplastic harimo guhumeka neza no kumva unaniwe.

• Ibizamini bisuzuma amaraso n'amagufa bikoreshwa mugushakisha (gushakisha) no gusuzuma syndromes ya myelodysplastic.

• Ibintu bimwe bigira ingaruka kumahitamo no kuvura.

Syndromes ya Myelodysplastic ni itsinda rya kanseri aho uturemangingo twamaraso tudakuze mumitsi yamagufwa adakura cyangwa ngo ahinduke selile nziza.

Mu muntu muzima, igufwa ryamagufa ritera ingirangingo zamaraso (selile zidakuze) zihinduka ingirabuzimafatizo zikuze mugihe runaka.

Anatomy yamagufwa. Igufwa rigizwe n'amagufwa magufi, amagufwa ya spongy, n'amagufwa. Amagufwa magufi agize igice cyinyuma cyamagufwa. Amagufwa ya spongy aboneka cyane kumpera yamagufa kandi arimo umusemburo utukura. Amagufwa yo mu magufa aboneka hagati yamagufwa menshi kandi afite imiyoboro myinshi yamaraso. Hariho ubwoko bubiri bwamagufwa: umutuku numuhondo. Umutuku utukura urimo ingirangingo z'amaraso zishobora guhinduka selile zitukura, selile yera, cyangwa platine. Umuhondo wumuhondo ugizwe ahanini namavuta.

Ingirabuzimafatizo y'amaraso irashobora guhinduka lymphoide stem selile cyangwa myeloid stem selile. Lymphoide stem selile iba selile yera. Ingirabuzimafatizo ya myeloid ihinduka bumwe mu bwoko butatu bw'amaraso akuze:

• Uturemangingo twamaraso dutukura dutwara ogisijeni nibindi bintu mubice byose byumubiri.

• Amashanyarazi akora amaraso kugirango areke kuva amaraso.

• Utugingo ngengabuzima twera turwanya indwara n'indwara.

Gukura kw'amaraso. Ingirabuzimafatizo y'amaraso inyura mu ntambwe nyinshi kugirango ihinduke selile itukura, platine, cyangwa selile yera.

Ku murwayi urwaye syndrome ya myelodysplastic, ingirangingo z'amaraso (selile zidakuze) ntizihinduka ingirabuzimafatizo zitukura zikuze, selile yera, cyangwa platine mu magufa. Izi selile zidakuze, zitwa guturika, ntizikora nkuko bikwiye kandi zipfa mumagufwa cyangwa nyuma gato yo kujya mumaraso. Ibi bisiga umwanya muto uturemangingo twamaraso twiza, selile zitukura, hamwe na platine kugirango bibe mumagufwa. Iyo hari selile nkeya zamaraso, kwandura, kubura amaraso, cyangwa kuva amaraso byoroshye.

Ubwoko butandukanye bwa syndromes ya myelodysplastic isuzumwa hashingiwe ku mpinduka zimwe na zimwe ziba mu maraso no mu magufa.

• Amaraso makeya: Amaraso atukura cyane mumaraso kandi umurwayi afite amaraso make. Umubare w'uturemangingo tw'amaraso yera na platine ni ibisanzwe.

• Anemia yubusa hamwe nimpeta ya sideroblasts: Hano mumaraso harimo selile nkeya zitukura mumaraso kandi umurwayi afite anemia. Uturemangingo twamaraso dutukura dufite fer nyinshi imbere muri selile. Umubare w'uturemangingo tw'amaraso yera na platine ni ibisanzwe.

• Amaraso make yangiritse hamwe no guturika birenze: Hariho amaraso make atukura mumaraso kandi umurwayi afite amaraso make. Ibice bitanu kw'ijana gushika kuri 19% by'utugingo ngengabuzima two mu magufa ni uguturika. Hashobora kandi guhinduka kumaraso yera na platine. Anemia yoroheje hamwe nibisasu birenze bishobora gutera imbere kuri acute myeloid leukemia (AML). Reba Abakuze Acute Myeloid Leukemia yo kuvura kubindi bisobanuro.

• Cytopenia yangiritse hamwe na dysplasia ya multilineage: Hariho bike cyane mubwoko bubiri bw'uturemangingo tw'amaraso (selile itukura, platine, cyangwa selile yera). Hafi ya 5% ya selile zo mumagufa ni uguturika naho munsi ya 1% ya selile mumaraso ni uguturika. Niba uturemangingo twamaraso dutukura twibasiwe, barashobora kugira fer yinyongera. Cytopenia yangiritse irashobora gutera imbere ikaze myeloid leukemia (AML).

• Cytopenia yangiritse hamwe na dysplasia unilineage: Hariho bike cyane mubwoko bumwe bwamaraso (selile yamaraso itukura, platine, cyangwa selile yera). Hariho impinduka muri 10% cyangwa zirenga mubwoko bubiri bwamaraso. Hafi ya 5% ya selile zo mumagufwa ni uguturika kandi munsi ya 1% ya selile mumaraso ni uguturika.

• Indwara ya myelodysplastic idasobanutse: Umubare wibisasu mumitsi yamagufa namaraso nibisanzwe, kandi indwara ntabwo ari imwe mubindi syndromes ya myelodysplastic.

• Indwara ya Myelodysplastic ifitanye isano na delos (5q) ya chromosome idasanzwe: Hano mu maraso harimo selile nkeya zitukura kandi umurwayi afite amaraso make. Hafi ya 5% ya selile zo mumagufwa namaraso ni uguturika. Hariho impinduka zihariye muri chromosome.

• Indwara ya myelomonocytic idakira (CMML): Reba incamake ya kuri Myelodysplastic / Myeloproliferative Neoplasms Kuvura amakuru menshi.

Imyaka hamwe nubuvuzi bwa kera hamwe na chimiotherapie cyangwa imiti ivura imirasire bigira ingaruka kumyanya myelodysplastic syndrome.

Ikintu cyose cyongera ibyago byo kwandura byitwa impanuka. Kugira ibintu bishobora guteza ingaruka ntabwo bivuze ko uzarwara; kutagira ibyago bishobora gusobanura ko utazarwara. Vugana na muganga wawe niba utekereza ko ushobora guhura n'akaga. Impamvu zishobora gutera syndromes ya myelodysplastic zirimo ibi bikurikira:

• Ubuvuzi bwa kera hamwe na chimiotherapie cyangwa imiti ivura kanseri.

• Guhura n’imiti imwe n'imwe, harimo umwotsi w'itabi, imiti yica udukoko, ifumbire, hamwe n'umuti nka benzene.

• Guhura nibyuma biremereye, nka mercure cyangwa gurş.

Impamvu ya syndromes ya myelodysplastic mubarwayi benshi ntabwo izwi.

Ibimenyetso nibimenyetso bya syndrome ya myelodysplastic harimo guhumeka neza no kumva unaniwe.

Syndromes ya Myelodysplastic akenshi ntabwo itera ibimenyetso cyangwa ibimenyetso hakiri kare. Bashobora kuboneka mugihe cyo kwisuzumisha bisanzwe. Ibimenyetso nibimenyetso bishobora guterwa na syndromes ya myelodysplastic cyangwa nibindi bihe. Menyesha umuganga wawe niba ufite kimwe muri ibi bikurikira:

• Kubura umwuka.

• Intege nke cyangwa kumva unaniwe.

• Kugira uruhu rwera kuruta uko byari bisanzwe.

• Gukomeretsa byoroshye cyangwa kuva amaraso.

• Petechiae (ibibara binini, bitagaragara munsi yuruhu biterwa no kuva amaraso).

Ibizamini bisuzuma amaraso n'amagufa bikoreshwa mugushakisha (gushakisha) no gusuzuma syndromes ya myelodysplastic.

Ibizamini hamwe nuburyo bukurikira birashobora gukoreshwa:

• Ikizamini cyumubiri namateka: Ikizamini cyumubiri kugirango ugenzure ibimenyetso rusange byubuzima, harimo no gusuzuma ibimenyetso byindwara, nkibibyimba cyangwa ikindi kintu cyose gisa nkidasanzwe. Hazafatwa kandi amateka yubuzima bwumurwayi nindwara zashize hamwe nubuvuzi.

• Umubare wuzuye wamaraso (CBC) ufite itandukaniro: Uburyo bwo gukuramo urugero rwamaraso no gusuzuma ibi bikurikira:

Umubare w'uturemangingo tw'amaraso atukura na platine.

• Umubare nubwoko bwingirangingo zamaraso yera.

• Ingano ya hemoglobine (proteyine itwara ogisijeni) mu ngirangingo z'amaraso atukura.

• Igice cyicyitegererezo cyamaraso kigizwe ningirabuzimafatizo zitukura.

Kubara amaraso yuzuye (CBC). Amaraso akusanywa no kwinjiza inshinge mumitsi no kwemerera amaraso gutembera mumiyoboro. Icyitegererezo cyamaraso cyoherezwa muri laboratoire hanyuma selile zitukura, selile yera, na platine zirabaze. CBC ikoreshwa mugupima, gusuzuma, no gukurikirana ibintu byinshi bitandukanye.

• Amaraso ya periferique: Uburyo bwo gusuzuma urugero rwamaraso kugirango hamenyekane impinduka mumibare, ubwoko, imiterere, nubunini bwingirangingo zamaraso hamwe nicyuma kinini mumasemburo atukura.

• Isesengura rya Cytogenetike: Ikizamini cya laboratoire aho chromosomes yingirabuzimafatizo ziri mu cyitegererezo cy’amagufwa cyangwa amaraso zibarwa kandi zikagenzurwa niba hari impinduka, nko kuvunika, kubura, gutondekanya, cyangwa chromosomes ziyongera. Impinduka muri chromosomes zimwe zishobora kuba ikimenyetso cya kanseri. Isesengura rya Cytogenetike rikoreshwa mu gufasha gusuzuma kanseri, gutegura gahunda yo kuvura, cyangwa kumenya uburyo ubuvuzi bukora neza.

• Ubushakashatsi bwa chimie yamaraso: Uburyo bwo gusuzuma urugero rwamaraso kugirango bapime urugero rwibintu bimwe na bimwe, nka vitamine B12 na folate, bisohoka mu maraso ningingo hamwe nuduce twumubiri. Umubare udasanzwe (uri hejuru cyangwa uri munsi yubusanzwe) ibintu bishobora kuba ikimenyetso cyindwara.

• Amagufa ya marrow aspiration na biopsy: Gukuraho igufwa ryamagufa, amaraso, nigice gito cyamagufwa winjiza urushinge rudafite epfo na ruguru cyangwa amabere. Inzobere mu by'indwara ireba amagufwa, amaraso, n'amagufwa munsi ya microscope kugirango ishakishe ingirabuzimafatizo zidasanzwe.

Amagufa ya marrow icyifuzo na biopsy. Nyuma yuko agace gato k'uruhu kamaze kunanirwa, urushinge rw'amagufwa rwinjizwa mu igufwa ry'umurwayi. Ingero z'amaraso, amagufwa, n'amagufwa byavanyweho kugirango bisuzumwe kuri microscope.

Ibizamini bikurikira birashobora gukorwa kurugero rwa tissue yakuweho:

• Immunocytochemie: Ikizamini cya laboratoire ikoresha antibodies kugirango igenzure antigene zimwe na zimwe (marikeri) mu cyitegererezo cy'amagufwa y'umurwayi. Antibodies zisanzwe zifitanye isano na enzyme cyangwa irangi rya fluorescent. Antibodies zimaze guhuza na antigen murugero rwingirabuzimafatizo z'umurwayi, enzyme cyangwa irangi birakorwa, hanyuma antigen irashobora kuboneka munsi ya microscope. Ubu bwoko bwikizamini bukoreshwa mugufasha gusuzuma kanseri no kuvuga itandukaniro riri hagati ya syndromes ya myelodysplastic, leukemia, nibindi bihe.

• Immunophenotyping: Ikizamini cya laboratoire ikoresha antibodies kugirango hamenyekane kanseri ya kanseri ukurikije ubwoko bwa antigene cyangwa ibimenyetso hejuru ya selile. Iki kizamini gikoreshwa mugufasha gusuzuma ubwoko bwihariye bwa leukemia nizindi ndwara zamaraso.

• Flow cytometry: Ikizamini cya laboratoire gipima umubare w'utugingo ngengabuzima, ijanisha ry'utugingo ngengabuzima turi mu cyitegererezo, hamwe n'ibiranga ingirabuzimafatizo, nk'ubunini, imiterere, hamwe n'ibimenyetso by'ibibyimba (cyangwa ibindi) kuri Ubuso. Ingirabuzimafatizo ziva mu cyitegererezo cy'amaraso y'umurwayi, igufwa ry'amagufa, cyangwa izindi ngingo zandujwe irangi rya fluorescent, zishyirwa mu mazi, hanyuma zikanyura rimwe na rimwe binyuze mu rumuri. Ibisubizo by'ibizamini bishingiye ku kuntu ingirabuzimafatizo zandujwe irangi rya fluorescent zifata urumuri. Iki kizamini gikoreshwa mugufasha gusuzuma no gucunga ubwoko bumwe na bumwe bwa kanseri, nka leukemia na lymphoma.

• AMAFI (fluorescence in situ hybridisation): Ikizamini cya laboratoire ikoreshwa mu kureba no kubara gen cyangwa chromosomes mu ngirabuzimafatizo no mu ngingo. Ibice bya ADN birimo amarangi ya fluorescent bikozwe muri laboratoire hanyuma bikongerwaho icyitegererezo cy'uturemangingo cyangwa ingirangingo z'umurwayi. Iyo ibyo bice bisize irangi bya ADN bifatanye na genes cyangwa uduce twa chromosomes murugero, biramurika iyo urebye munsi ya microscope ya fluorescent. Ikizamini cya FISH gikoreshwa mugufasha gusuzuma kanseri no gufasha kuvura.

Ibintu bimwe bigira ingaruka kumahitamo no kuvura.

Kumenyekanisha (amahirwe yo gukira) hamwe nuburyo bwo kuvura biterwa nibi bikurikira:

• Umubare w'utugingo ngengabuzima two mu magufa.

• Niba ubwoko bumwe cyangwa bwinshi bwingirangingo zamaraso bigira ingaruka.

• Niba umurwayi afite ibimenyetso cyangwa ibimenyetso byo kubura amaraso, kuva amaraso, cyangwa kwandura.

• Niba umurwayi afite ibyago bike cyangwa byinshi byo kurwara leukemia.

• Impinduka zimwe muri chromosomes.

• Indwara ya myelodysplastic yabayeho nyuma ya chimiotherapie cyangwa imiti ivura kanseri.

• Imyaka nubuzima rusange bwumurwayi.

Incamake yo kuvura

INGINGO Z'INGENZI

• Hariho uburyo butandukanye bwo kuvura abarwayi bafite syndromes ya myelodysplastic.

• Kuvura syndromes ya myelodysplastic harimo ubuvuzi bufasha, kuvura imiti, hamwe no guhinduranya ingirabuzimafatizo.

• Ubwoko butatu bwo kuvura busanzwe bukoreshwa:

• Kwitaho ubufasha

• Kuvura ibiyobyabwenge

• Chimoterapi hamwe no guhinduranya ingirangingo

• Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.

• Umuti wa syndromes ya myelodysplastic urashobora gutera ingaruka mbi.

• Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.

• Abarwayi barashobora kwinjira mu mavuriro mbere, mugihe, cyangwa nyuma yo gutangira kwivuza.

• Ibizamini byo gukurikirana birashobora gukenerwa.

Hariho uburyo butandukanye bwo kuvura abarwayi bafite syndromes ya myelodysplastic.

Ubwoko butandukanye bwo kuvura burahari kubarwayi bafite syndromes ya myelodysplastic. Bumwe mu buryo busanzwe (ubuvuzi bukoreshwa ubu), kandi bumwe burimo kugeragezwa mubigeragezo byamavuriro. Ikigeragezo kivura ni ubushakashatsi bwakozwe bugamije gufasha kunoza imiti igezweho cyangwa kubona amakuru ku buvuzi bushya ku barwayi ba kanseri. Iyo ibizamini byo kwa muganga byerekana ko ubuvuzi bushya buruta ubuvuzi busanzwe, ubuvuzi bushya bushobora kuba ubuvuzi busanzwe. Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga. Ibigeragezo bimwe na bimwe bivura abarwayi batatangiye kwivuza.

Kuvura syndromes ya myelodysplastic harimo ubuvuzi bufasha, kuvura imiti, hamwe no guhinduranya ingirabuzimafatizo.

Abarwayi bafite syndrome ya myelodysplastic bafite ibimenyetso biterwa no kubara amaraso make bahabwa ubufasha bufasha kugabanya ibimenyetso no kuzamura imibereho. Ubuvuzi bwibiyobyabwenge burashobora gukoreshwa mugutinda gutera imbere kwindwara. Bamwe mu barwayi barashobora gukira hakoreshejwe imiti ikaze hamwe na chimiotherapie ikurikirwa no guterwa ingirangingo fatizo bakoresheje ingirabuzimafatizo ziva mu baterankunga.

Ubwoko butatu bwo kuvura busanzwe bukoreshwa:

Kwitaho ubufasha

Hitaweho ubufasha bugamije kugabanya ibibazo biterwa n'indwara cyangwa kuyivura. Ubuvuzi bufasha bushobora kubamo ibi bikurikira:

• Ubuvuzi bwo guterwa

Ubuvuzi bwa Transfusion (transfusion blood) nuburyo bwo gutanga selile zitukura, selile yera, cyangwa platine kugirango bisimbuze selile yamaraso yangijwe nindwara cyangwa kwivuza. Gutanga amaraso atukura atangwa mugihe umubare wamaraso utukura uba muke kandi ibimenyetso cyangwa ibimenyetso bya anemia, nko guhumeka neza cyangwa kumva unaniwe cyane, bibaho. Guterwa kwa platine mubisanzwe bitangwa mugihe umurwayi ava amaraso, afite uburyo bushobora gutera kuva amaraso, cyangwa mugihe umubare wa platel ari muke cyane.

Abarwayi bahabwa amaraso menshi ya selile barashobora kugira ingirangingo no kwangirika kwingingo ziterwa no kwiyongera kwicyuma. Aba barwayi barashobora kuvurwa hakoreshejwe imiti ya chelation kugirango bakure fer yongeyeho mumaraso.

• Erythropoiesis-itera imbaraga

Erythropoiesis-itera imbaraga (ESAs) irashobora gutangwa kugirango yongere umubare wamaraso atukura akuze yakozwe numubiri no kugabanya ingaruka ziterwa no kubura amaraso. Rimwe na rimwe, granulocyte colony-itera imbaraga (G-CSF) itangwa hamwe na ESA kugirango ifashe kuvura neza.

• Ubuvuzi bwa antibiyotike

Antibiyotike irashobora gutangwa kugirango irwanye kwandura.

Kuvura ibiyobyabwenge

• Lenalidomide

Abarwayi bafite syndrome ya myelodysplastic ifitanye isano na chromosome idasanzwe ya del (5q) idasanzwe ikenera guterwa kenshi mumaraso atukura barashobora kuvurwa na lenalidomide. Lenalidomide ikoreshwa mu kugabanya ibikenerwa guterwa amaraso atukura.

• Immunosuppressive therapy

Antithymocyte globuline (ATG) ikora kugirango ihagarike cyangwa igabanye ubudahangarwa bw'umubiri. Ikoreshwa mukugabanya gukenera guterwa amaraso atukura.

• Azacitidine na decitabine

Azacitidine na decitabine bikoreshwa mukuvura syndromes ya myelodysplastic mukwica selile zigabanuka vuba. Bafasha kandi ingirabuzimafatizo zigira uruhare mu mikurire ya selile gukora uko bikwiye. Umuti hamwe na azacitidine na decitabine urashobora kudindiza iterambere rya syndromes ya myelodysplastic kuri acute myeloid leukemia.

• Chimoterapi ikoreshwa muri acute myeloid leukemia (AML)

Abarwayi bafite syndrome ya myelodysplastic hamwe numubare munini wibisasu mumagufwa yabo bafite ibyago byinshi byo kurwara leukemia ikaze. Bashobora kuvurwa hamwe na chimiotherapie imwe ikoreshwa kubarwayi barwaye leukemia ikaze.

Chimoterapi hamwe no guhinduranya ingirangingo

Chimiotherapie itangwa kugirango yice kanseri. Ingirabuzimafatizo nzima, harimo na selile zikora amaraso, nazo zirasenywa no kuvura kanseri. Gutera ingirabuzimafatizo ni uburyo bwo gusimbuza ingirabuzimafatizo. Ingirabuzimafatizo (selile zidakuze) zivanwa mumaraso cyangwa igufwa ryumurwayi cyangwa umuterankunga hanyuma bikonjeshwa bikabikwa. Nyuma yuko umurwayi arangije chimiotherapie, ingirangingo zibitswe zabitswe kandi zisubizwa umurwayi binyuze mu gushiramo. Izi ngirabuzimafatizo zongeye gukoreshwa zikura (kandi zigarura) ingirangingo z'amaraso z'umubiri.

Ubu buvuzi ntibushobora gukora neza kubarwayi bafite syndrome ya myelodysplastic yatewe no kuvura kanseri.

Gutera ingirabuzimafatizo. (Intambwe ya 1): Amaraso yakuwe mumitsi mumaboko yumuterankunga. Umurwayi cyangwa undi muntu ashobora kuba umuterankunga. Amaraso atembera mumashini ikuraho ingirabuzimafatizo. Noneho amaraso asubizwa abaterankunga binyuze mumitsi mumaboko yandi. (Intambwe ya 2): Umurwayi yakira chimiotherapie kugirango yice selile zikora amaraso. Umurwayi arashobora guhabwa imiti ivura imirasire (iterekanwa). (Intambwe ya 3): Umurwayi yakira ingirabuzimafatizo binyuze muri catheter yashyizwe mu maraso mu gituza.

Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.

Amakuru yerekeye ibizamini byamavuriro araboneka kurubuga rwa NCI.

Umuti wa syndromes ya myelodysplastic urashobora gutera ingaruka mbi.

Kumakuru yingaruka ziterwa no kuvura kanseri, reba urupapuro rwuruhande rwacu.

Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.

Ku barwayi bamwe, kwitabira ikizamini cyamavuriro birashobora kuba uburyo bwiza bwo kuvura. Ibigeragezo bivura biri mubikorwa byubushakashatsi bwa kanseri. Igeragezwa rya Clinical rikorwa kugirango hamenyekane niba imiti mishya ya kanseri itekanye kandi ifite akamaro cyangwa nziza kuruta ubuvuzi busanzwe.

Benshi mubuvuzi busanzwe bwa kanseri bushingiye kubigeragezo byambere byubuvuzi. Abarwayi bitabiriye kwipimisha barashobora kuvurwa bisanzwe cyangwa kuba mubambere bahawe imiti mishya.

Abarwayi bitabira ibizamini byo kwa muganga nabo bafasha kunoza uburyo kanseri izavurwa mugihe kizaza. Nubwo ibigeragezo bivura bitaganisha ku buvuzi bushya, akenshi basubiza ibibazo byingenzi kandi bigafasha gutera imbere ubushakashatsi.

Abarwayi barashobora kwinjira mu mavuriro mbere, mugihe, cyangwa nyuma yo gutangira kwivuza.

Igeragezwa rimwe na rimwe ririmo abarwayi bataravurwa. Ibindi bigeragezo bipima abarwayi bafite kanseri itameze neza. Hariho kandi ibizamini byo kwa muganga bipima uburyo bushya bwo guhagarika kanseri kongera kugaruka (kugaruka) cyangwa kugabanya ingaruka zo kuvura kanseri.

Igeragezwa rya Clinical ririmo kubera mu bice byinshi by'igihugu. Amakuru yerekeye ibizamini byamavuriro ashyigikiwe na NCI urashobora kubisanga kurubuga rwa NCI. Ibizamini bya Clinical bishyigikiwe nandi mashyirahamwe murashobora kubisanga kurubuga rwa ClinicalTrials.gov.

Ibizamini byo gukurikirana birashobora gukenerwa.

Bimwe mubizamini byakozwe mugupima kanseri cyangwa kumenya icyiciro cya kanseri birashobora gusubirwamo. Ibizamini bimwe bizasubirwamo kugirango harebwe uburyo ubuvuzi bukora neza. Ibyemezo bijyanye no gukomeza, guhindura, cyangwa guhagarika ubuvuzi birashobora gushingira kubisubizo byibi bizamini.

Bimwe mubizamini bizakomeza gukorwa buri gihe nyuma yubuvuzi burangiye. Ibisubizo by'ibi bizamini birashobora kwerekana niba ubuzima bwawe bwarahindutse cyangwa niba kanseri yarongeye (garuka). Ibi bizamini rimwe na rimwe byitwa gukurikirana-ibizamini cyangwa kugenzura.

Amahitamo yo kuvura Syndromes ya Myelodysplastic

Kumakuru yerekeye imiti yavuzwe hepfo, reba igice cyo kuvura.

Amahitamo asanzwe yo kuvura Syndromes ya Myelodysplastic

Uburyo busanzwe bwo kuvura syndromes ya myelodysplastic harimo:

• Kwitaho ubufasha hamwe numwe cyangwa benshi muribi bikurikira:

• Ubuvuzi bwo guterwa.

• Erythropoiesis-itera imbaraga.

• Ubuvuzi bwa antibiyotike.

• Umuti wo gutinda gutera imbere kuri acute myeloid leukemia (AML):

• Lenalidomide.

• Immunosuppressive therapy.

• Azacitidine na decitabine.

• Chimoterapi ikoreshwa muri acute myeloid leukemia.

• Chimoterapi hamwe no guhinduranya ingirangingo.

Ubuvuzi bwa Myeloid Neoplasms

Abarwayi bavuwe kera hamwe na chimiotherapie cyangwa imiti ivura imirasire barashobora kurwara myeloid neoplasme ijyanye nubuvuzi. Amahitamo yo kuvura ni kimwe nizindi syndromes ya myelodysplastic.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Amahitamo yo kuvura Syndromes ya Myelodysplastic Yasubiwemo cyangwa Yanze

Kumakuru yerekeye imiti yavuzwe hepfo, reba igice cyo kuvura.

Nta buryo busanzwe bwo kuvura syndromes ya myelodysplastic yongeye kugaruka. Abarwayi bafite kanseri ititabira kwivuza cyangwa bagarutse nyuma yo kuvurwa barashobora kwitabira kwisuzumisha kwa muganga.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Kumenya byinshi kuri Syndromes ya Myelodysplastic

Ushaka amakuru menshi yikigo cyigihugu cya kanseri kubyerekeye syndromes ya myelodysplastic, reba ibi bikurikira:

• Gutera Amaraso Yimitsi Yimitsi

Kumakuru rusange ya kanseri nibindi bikoresho biva mu kigo cyigihugu cya kanseri, reba ibi bikurikira:

• Ibyerekeye Kanseri

• Gutegura

• Chimiotherapie nawe: Inkunga kubantu barwaye Kanseri

• Ubuvuzi bwimirasire nawe: Inkunga kubantu barwaye Kanseri

• Guhangana na Kanseri

• Ibibazo byo Kubaza Muganga wawe kuri Kanseri

• Abacitse ku icumu n'abarezi

• Ibyerekeye Iyi ncamake ya