Types/myeloproliferative/patient/mds-mpd-treatment-pdq

Myelodysplastic / Umuti wa Myeloproliferative Neoplasms (®) –Umurwayi

Amakuru Rusange Yerekeye Myelodysplastic / Myeloproliferative Neoplasms

INGINGO Z'INGENZI

• Myelodysplastic / myeloproliferative neoplasms ni itsinda ryindwara aho igufwa ryamagufa rikora selile nyinshi zera.

• Myelodysplastic / myeloproliferative neoplasms ifite ibiranga syndromes ya myelodysplastic na myeloproliferative neoplasms.

• Hariho ubwoko butandukanye bwa myelodysplastic / myeloproliferative neoplasms.

• Ibizamini bisuzuma amaraso n'amagufa bikoreshwa mugushakisha (gushakisha) no gusuzuma myelodysplastic / myeloproliferative neoplasms.

Myelodysplastic / myeloproliferative neoplasms ni itsinda ryindwara aho igufwa ryamagufa rikora selile nyinshi zera.

Myelodysplastic / myeloproliferative neoplasms ni indwara zamaraso hamwe nigifu.

Anatomy yamagufwa. Igufwa rigizwe n'amagufwa magufi, amagufwa ya spongy, n'amagufwa. Amagufwa magufi agize igice cyinyuma cyamagufwa. Amagufwa ya spongy aboneka cyane kumpera yamagufa kandi arimo umusemburo utukura. Amagufwa yo mu magufa aboneka hagati yamagufwa menshi kandi afite imiyoboro myinshi yamaraso. Hariho ubwoko bubiri bwamagufwa: umutuku numuhondo. Umutuku utukura urimo ingirangingo z'amaraso zishobora guhinduka selile zitukura, selile yera, cyangwa platine. Umuhondo wumuhondo ugizwe ahanini namavuta.

Mubisanzwe, igufwa ryamagufa ritera ingirangingo zamaraso (selile zidakuze) zihinduka selile yamaraso ikuze mugihe runaka. Ingirabuzimafatizo y'amaraso irashobora guhinduka myeloid stem selile cyangwa lymphoide stem selile. Lymphoide stem selile iba selile yera. Ingirabuzimafatizo ya myeloid ihinduka bumwe mu bwoko butatu bw'amaraso akuze:

• Uturemangingo twamaraso dutukura dutwara ogisijeni nibindi bintu mubice byose byumubiri.

• Utugingo ngengabuzima twera turwanya indwara n'indwara.

• Amashanyarazi akora amaraso kugirango areke kuva amaraso.

Gukura kw'amaraso. Ingirabuzimafatizo y'amaraso inyura mu ntambwe nyinshi kugirango ihinduke selile itukura, platine, cyangwa selile yera.

Myelodysplastic / myeloproliferative neoplasms ifite ibiranga syndromes ya myelodysplastic na myeloproliferative neoplasms.

Mu ndwara za myelodysplastic, ingirangingo z'amaraso ntizikura mu maraso meza atukura, selile yera, cyangwa platine. Ingirabuzimafatizo zamaraso zidakuze, zitwa guturika, ntizikora uko bikwiye kandi zipfa mumagufwa cyangwa nyuma gato yo kwinjira mumaraso. Kubera iyo mpamvu, hari selile nkeya zitukura zifite ubuzima bwiza, selile yera, na platine.

Mu ndwara za myeloproliferative, umubare urenze umubare usanzwe w'uturemangingo tw'amaraso duhinduka ubwoko bumwe cyangwa bwinshi bw'uturemangingo tw'amaraso kandi umubare w'uturemangingo twamaraso twiyongera buhoro buhoro.

Iyi ncamake ivuga kuri neoplasme ifite ibimenyetso byindwara ya myelodysplastic na myeloproliferative. Reba incamake ya ikurikira kugirango umenye amakuru yerekeye indwara zifitanye isano:

• Indwara ya Myelodysplastic

• Umuti uhoraho wa Myeloproliferative Neoplasms

• Umuti wa karande Myelogenous Leukemia

Hariho ubwoko butandukanye bwa myelodysplastic / myeloproliferative neoplasms.

Ubwoko 3 bwingenzi bwa myelodysplastic / myeloproliferative neoplasms harimo ibi bikurikira:

• Indwara ya myelomonocytic idakira (CMML).

• Umwana muto myelomonocytic leukemia (JMML).

• Indwara idasanzwe ya myelogenous leukemia (CML).

Iyo myelodysplastic / myeloproliferative neoplasm idahuye na bumwe muri ubwo bwoko, bwitwa myelodysplastic / myeloproliferative neoplasm, idasobanutse (MDS / MPN-UC).

Myelodysplastic / myeloproliferative neoplasms irashobora gutera imbere ikabije ya leukemia.

Ibizamini bisuzuma amaraso n'amagufa bikoreshwa mugushakisha (gushakisha) no gusuzuma myelodysplastic / myeloproliferative neoplasms.

Ibizamini hamwe nuburyo bukurikira birashobora gukoreshwa:

• Ikizamini cyumubiri namateka: Ikizamini cyumubiri kugirango hamenyekane ibimenyetso rusange byubuzima, harimo no gusuzuma ibimenyetso byindwara nkumugongo wagutse numwijima. Hazafatwa kandi amateka yubuzima bwumurwayi nindwara zashize hamwe nubuvuzi.

• Umubare wuzuye wamaraso (CBC) ufite itandukaniro: Uburyo bwo gukuramo urugero rwamaraso no gusuzuma ibi bikurikira:

• Umubare w'uturemangingo tw'amaraso atukura na platine.

• Umubare nubwoko bwingirangingo zamaraso yera.

• Ingano ya hemoglobine (proteyine itwara ogisijeni) mu ngirangingo z'amaraso atukura.

• Igice cy'icyitegererezo kigizwe na selile zitukura.

Kubara amaraso yuzuye (CBC). Amaraso akusanywa no kwinjiza inshinge mumitsi no kwemerera amaraso gutembera mumiyoboro. Icyitegererezo cyamaraso cyoherezwa muri laboratoire hanyuma selile zitukura, selile yera, na platine zirabaze. CBC ikoreshwa mugupima, gusuzuma, no gukurikirana ibintu byinshi bitandukanye.

• Amaraso ya periferique: Uburyo bwo gusuzuma urugero rwamaraso kugirango hamenyekane selile ziturika, umubare nubwoko bwingirangingo zamaraso yera, umubare wa platine, hamwe nimpinduka mumiterere ya selile.

• Ubushakashatsi bwa chimie yamaraso: Uburyo bwo gusuzuma urugero rwamaraso kugirango bapime urugero rwibintu bimwe na bimwe bisohoka mumaraso ningingo nuduce twumubiri. Umubare udasanzwe (uri hejuru cyangwa uri munsi yubusanzwe) ibintu bishobora kuba ikimenyetso cyindwara.

• Amagufa ya marrow aspiration na biopsy: Gukuraho agace gato k'amagufwa n'amagufwa winjiza urushinge mumatako cyangwa amabere. Inzobere mu bijyanye n’indwara ireba amagufwa n’amagufwa munsi ya microscope kugirango ishakishe selile zidasanzwe.

Amagufa ya marrow icyifuzo na biopsy. Nyuma yuko agace gato k'uruhu kamaze kunanirwa, urushinge rw'amagufwa rwinjizwa mu igufwa ry'umurwayi. Ingero z'amaraso, amagufwa, n'amagufwa byavanyweho kugirango bisuzumwe kuri microscope.

Ibizamini bikurikira birashobora gukorwa kurugero rwa tissue yakuweho:

• Isesengura rya Cytogenetike: Ikizamini cya laboratoire aho chromosomes yingirabuzimafatizo ziri mu cyitegererezo cy’amagufwa cyangwa amaraso zibarwa kandi zikagenzurwa niba hari impinduka, nko kuvunika, kubura, gutondekanya, cyangwa chromosomes ziyongera. Impinduka muri chromosomes zimwe zishobora kuba ikimenyetso cya kanseri. Isesengura rya Cytogenetike rikoreshwa mu gufasha gusuzuma kanseri, gutegura gahunda yo kuvura, cyangwa kumenya uburyo ubuvuzi bukora neza. Ingirabuzimafatizo za kanseri muri myelodysplastic / myeloproliferative neoplasms ntabwo irimo chromosome ya Philadelphia iboneka muri leukemia idakira.

• Immunocytochemie: Ikizamini cya laboratoire ikoresha antibodies kugirango igenzure antigene zimwe na zimwe (marikeri) mu cyitegererezo cy'amagufwa y'umurwayi. Antibodies zisanzwe zifitanye isano na enzyme cyangwa irangi rya fluorescent. Antibodies zimaze guhuza antigen murugero rwamagufwa yumurwayi, enzyme cyangwa irangi birakorwa, hanyuma antigen irashobora kuboneka munsi ya microscope. Ubu bwoko bwikizamini bukoreshwa mugufasha gusuzuma kanseri no kuvuga itandukaniro riri hagati ya myelodysplastic / myeloproliferative neoplasms, leukemia, nibindi bihe.

Indwara ya Myelomonocytic idakira

INGINGO Z'INGENZI

• Indwara ya myelomonocytic idakira ni indwara aho myelocytes na monocytes nyinshi (selile yera itarakura) ikorwa mumagufwa.

• Ubusaza no kuba umugabo byongera ibyago byo kurwara myelomonocytic leukemia idakira.

• Ibimenyetso nibimenyetso bya myelomonocytic leukemia idakira harimo umuriro, guta ibiro, no kumva unaniwe cyane.

• Ibintu bimwe bigira ingaruka kubitekerezo (amahirwe yo gukira) hamwe nuburyo bwo kuvura.

Indwara ya myelomonocytic idakira ni indwara aho myelocytes na monocytes nyinshi (selile yera itarakura) ikorwa mumagufwa.

Muri myelomonocytic leukemia idakira (CMML), umubiri ubwira uturemangingo twinshi twamaraso kugirango duhinduke ubwoko bubiri bwamaraso yera yitwa myelocytes na monocytes. Zimwe muri izo selile stem selile ntizigera ziba selile yera ikuze. Utugingo ngengabuzima twera tutarakura byitwa guturika. Nyuma yigihe, myelocytes, monocytes, hamwe nibisasu byuzuyemo uturemangingo twamaraso dutukura hamwe na platine mu magufa. Iyo ibi bibaye, kwandura, kubura amaraso, cyangwa kuva amaraso byoroshye birashobora kubaho.

Ubusaza no kuba umugabo byongera ibyago byo kurwara myelomonocytic leukemia idakira.

Ikintu cyose cyongera amahirwe yo kwandura indwara cyitwa impanuka. Impamvu zishobora gutera ingaruka kuri CMML zirimo ibi bikurikira:

• Ubusaza.
• Kuba umugabo.
• Guhura nibintu bimwe na bimwe kukazi cyangwa mubidukikije.
• Guhura n'imirase.
• Ubuvuzi bwashize hamwe nibiyobyabwenge bimwe na bimwe birwanya antikanseri.

Ibimenyetso nibimenyetso bya myelomonocytic leukemia idakira harimo umuriro, guta ibiro, no kumva unaniwe cyane.

Ibi nibindi bimenyetso nibimenyetso bishobora guterwa na CMML cyangwa nibindi bihe. Menyesha umuganga wawe niba ufite kimwe muri ibi bikurikira:

• Umuriro nta mpamvu izwi.
• Indwara.
• Kumva unaniwe cyane.
• Kugabanya ibiro nta mpamvu izwi.
• Gukomeretsa byoroshye cyangwa kuva amaraso.
• Kubabara cyangwa kumva wuzuye munsi y'urubavu.

Ibintu bimwe bigira ingaruka kubitekerezo (amahirwe yo gukira) hamwe nuburyo bwo kuvura.

Kumenyekanisha (amahirwe yo gukira) hamwe nuburyo bwo kuvura CMML biterwa nibi bikurikira:

• Umubare w'uturemangingo tw'amaraso yera cyangwa platine mu maraso cyangwa mu magufa.

• Niba umurwayi adafite amaraso.

• Ingano yo guturika mumaraso cyangwa igufwa.

• Ingano ya hemoglobine mu ngirabuzimafatizo zitukura.

• Niba hari impinduka zimwe muri chromosomes.

Umwana muto Myelomonocytic Leukemia

INGINGO Z'INGENZI

• Leukemia yumwana muto ni indwara yo mu bwana aho myelocytes na monocytes nyinshi (selile yera idakuze) ikorwa mumagufwa.

• Ibimenyetso nibimenyetso bya leukemia yumwana muto harimo umuriro, guta ibiro, no kumva unaniwe cyane.

• Ibintu bimwe bigira ingaruka kubitekerezo (amahirwe yo gukira) hamwe nuburyo bwo kuvura.

Leukemia yumwana muto ni indwara yo mu bwana aho myelocytes na monocytes nyinshi (selile yera idakuze) ikorwa mumagufwa.

Juukile myelomonocytic leukemia (JMML) ni kanseri idasanzwe yo mu bwana igaragara cyane ku bana bari munsi yimyaka 2. Abana bafite neurofibromatose ubwoko bwa 1 nabagabo bafite ibyago byinshi byo kurwara myelomonocytic leukemia.

Muri JMML, umubiri ubwira uturemangingo twinshi twamaraso kugirango duhinduke ubwoko bubiri bwamaraso yera yitwa myelocytes na monocytes. Zimwe muri izo selile stem selile ntizigera ziba selile yera ikuze. Utugingo ngengabuzima twera tutarakura byitwa guturika. Nyuma yigihe, myelocytes, monocytes, hamwe nibisasu byuzuyemo uturemangingo twamaraso dutukura hamwe na platine mu magufa. Iyo ibi bibaye, kwandura, kubura amaraso, cyangwa kuva amaraso byoroshye birashobora kubaho.

Ibimenyetso nibimenyetso bya leukemia yumwana muto harimo umuriro, guta ibiro, no kumva unaniwe cyane.

Ibi nibindi bimenyetso nibimenyetso bishobora guterwa na JMML cyangwa nibindi bihe. Menyesha umuganga wawe niba ufite kimwe muri ibi bikurikira:

• Umuriro nta mpamvu izwi.

• Kugira indwara, nka bronchite cyangwa tonzillite.

• Kumva unaniwe cyane.

• Gukomeretsa byoroshye cyangwa kuva amaraso.

• Uruhu.

• Kubabara kutagira ububabare bwa lymph node mu ijosi, munsi yintoki, igifu, cyangwa igituba.

• Kubabara cyangwa kumva wuzuye munsi y'urubavu.

Ibintu bimwe bigira ingaruka kubitekerezo (amahirwe yo gukira) hamwe nuburyo bwo kuvura.

Kumenyekanisha (amahirwe yo gukira) hamwe nubuvuzi bwa JMML biterwa nibi bikurikira:

• Imyaka yumwana mugupima.

• Umubare wa platine mumaraso.

• Ingano yubwoko runaka bwa hemoglobine muri selile zitukura.

Indwara idasanzwe ya Myelogenous Leukemia

INGINGO Z'INGENZI

• Indwara idasanzwe ya myelogenous leukemia ni indwara ikorwa na granulocytes nyinshi (selile yera idakuze) ikorwa mumagufwa.

• Ibimenyetso nibimenyetso bya karande idasanzwe ya myelogenous leukemia harimo gukomeretsa byoroshye cyangwa kuva amaraso no kumva unaniwe kandi ufite intege nke.

• Ibintu bimwe bigira ingaruka kubimenyekanisha (amahirwe yo gukira).

Indwara idasanzwe ya myelogenous leukemia ni indwara ikorwa na granulocytes nyinshi (selile yera idakuze) ikorwa mumagufwa.

Muri kanseri idasanzwe ya myelogenous leukemia (CML), umubiri ubwira uturemangingo twinshi twamaraso kugirango duhinduke ubwoko bwamaraso yera yitwa granulocytes. Zimwe muri izo selile stem selile ntizigera ziba selile yera ikuze. Utugingo ngengabuzima twera tutarakura byitwa guturika. Igihe kirenze, granulocytes no guturika byuzuyemo uturemangingo twamaraso dutukura hamwe na platine mumitsi.

Ingirabuzimafatizo ya leukemia muri CML idasanzwe na CML isa kimwe na microscope. Ariko, muburyo budasanzwe bwa CML impinduka zimwe za chromosome, yitwa "Philadelphia chromosome" ntabwo ihari.

Ibimenyetso nibimenyetso bya karande idasanzwe ya myelogenous leukemia harimo gukomeretsa byoroshye cyangwa kuva amaraso no kumva unaniwe kandi ufite intege nke.

Ibi nibindi bimenyetso nibimenyetso bishobora guterwa na CML idasanzwe cyangwa nibindi bihe. Menyesha umuganga wawe niba ufite kimwe muri ibi bikurikira:

• Kubura umwuka.

• Uruhu rwera.

• Kumva unaniwe cyane kandi ufite intege nke.

• Gukomeretsa byoroshye cyangwa kuva amaraso.

• Petechiae (ibibara binini, bitagaragara munsi yuruhu biterwa no kuva amaraso).

• Kubabara cyangwa kumva wuzuye munsi yimbavu kuruhande rwibumoso.

Ibintu bimwe bigira ingaruka kubimenyekanisha (amahirwe yo gukira).

Kumenyekanisha (amahirwe yo gukira) kuri CML idasanzwe biterwa numubare w'uturemangingo twamaraso dutukura na platine mumaraso.

Myelodysplastic / Myeloproliferative Neoplasm, Ntibishobora

INGINGO Z'INGENZI

• Myelodysplastic / myeloproliferative neoplasm, idasobanutse, ni indwara ifite ibimenyetso byindwara za myelodysplastic na myeloproliferative ariko ntabwo ari myelomonocytic leukemia idakira, leukemia yumwana myelomonocytic, cyangwa leukemia idasanzwe.

• Ibimenyetso nibimenyetso bya myelodysplastic / myeloproliferative neoplasm, idasobanutse, harimo umuriro, guta ibiro, no kumva unaniwe cyane.

Myelodysplastic / myeloproliferative neoplasm, idasobanutse, ni indwara ifite ibimenyetso byindwara za myelodysplastic na myeloproliferative ariko ntabwo ari myelomonocytic leukemia idakira, leukemia yumwana myelomonocytic, cyangwa leukemia idasanzwe.

Muri myelodysplastic / myeloproliferative neoplasm, idashobora kwemerwa (MDS / MPD-UC), umubiri ubwira uturemangingo twinshi twamaraso kugirango duhinduke selile yamaraso itukura, selile yera, cyangwa platine. Zimwe muri izo ngirabuzimafatizo zamaraso ntizigera ziba selile zikuze. Izi selile zidakuze zitwa guturika. Igihe kirenze, uturemangingo twamaraso adasanzwe no guturika mumagufwa yamagufa asohora uturemangingo twamaraso dutukura, selile yera, na platine.

MDS / MPN-UC ni indwara idasanzwe. Kuberako ari gake cyane, ibintu bigira ingaruka no guhanura ntabwo bizwi.

Ibimenyetso nibimenyetso bya myelodysplastic / myeloproliferative neoplasm, idasobanutse, harimo umuriro, guta ibiro, no kumva unaniwe cyane.

Ibi nibindi bimenyetso nibimenyetso bishobora guterwa na MDS / MPN-UC cyangwa nibindi bihe. Menyesha umuganga wawe niba ufite kimwe muri ibi bikurikira:

• Indwara cyangwa kwandura kenshi.

• Kubura umwuka.

• Kumva unaniwe cyane kandi ufite intege nke.

• Uruhu rwera.

• Gukomeretsa byoroshye cyangwa kuva amaraso.

• Petechiae (ibibara binini, bitagaragara munsi yuruhu biterwa no kuva amaraso).

• Kubabara cyangwa kumva wuzuye munsi y'urubavu.

Icyiciro cya Myelodysplastic / Myeloproliferative Neoplasms

INGINGO Z'INGENZI

• Nta sisitemu isanzwe yo kubika myelodysplastic / myeloproliferative neoplasms.

Nta sisitemu isanzwe yo kubika myelodysplastic / myeloproliferative neoplasms.

Gutegura ni inzira ikoreshwa mu kumenya intera kanseri imaze gukwirakwira. Nta sisitemu isanzwe yo kubika myelodysplastic / myeloproliferative neoplasms. Umuti ushingiye ku bwoko bwa myelodysplastic / myeloproliferative neoplasm umurwayi afite. Ni ngombwa kumenya ubwoko kugirango utegure kuvura.

Incamake yo kuvura

INGINGO Z'INGENZI

• Hariho uburyo butandukanye bwo kuvura abarwayi bafite myelodysplastic / myeloproliferative neoplasms.

• Ubwoko butanu bwo kuvura busanzwe bukoreshwa:

• Chimoterapi

• Ubundi buryo bwo kuvura ibiyobyabwenge

• Gutera ingirabuzimafatizo

• Kwitaho ubufasha

• Ubuvuzi bugamije

• Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.

• Umuti wa myelodysplastic / myeloproliferative neoplasms irashobora gutera ingaruka.

• Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.

• Abarwayi barashobora kwipimisha kwa muganga mbere, mugihe, cyangwa nyuma yo gutangira kuvura kanseri.

• Ibizamini byo gukurikirana birashobora gukenerwa.

Hariho uburyo butandukanye bwo kuvura abarwayi bafite myelodysplastic / myeloproliferative neoplasms.

Ubwoko butandukanye bwo kuvura burahari kubarwayi bafite myelodysplastic / myeloproliferative neoplasms. Bumwe mu buryo busanzwe (ubuvuzi bukoreshwa ubu), kandi bumwe burimo kugeragezwa mubigeragezo byamavuriro. Ikigeragezo kivura ni ubushakashatsi bwakozwe bugamije gufasha kunoza imiti igezweho cyangwa kubona amakuru ku buvuzi bushya ku barwayi ba kanseri. Iyo ibizamini byo kwa muganga byerekana ko ubuvuzi bushya buruta ubuvuzi busanzwe, ubuvuzi bushya bushobora kuba ubuvuzi busanzwe. Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga. Ibigeragezo bimwe na bimwe bivura abarwayi batatangiye kwivuza.

Ubwoko butanu bwo kuvura busanzwe bukoreshwa:

Chimoterapi

Chimoterapi ni umuti wa kanseri ukoresha ibiyobyabwenge kugirango uhagarike imikurire ya kanseri, haba mu kwica selile cyangwa kubabuza gutandukana. Iyo chimiotherapie ifashwe numunwa cyangwa igaterwa mumitsi cyangwa imitsi, imiti yinjira mumaraso kandi irashobora kugera kanseri ya kanseri mumubiri (chimiotherapie sisitemu). Iyo chimiotherapie ishyizwe mumazi yubwonko, urugingo, cyangwa umwobo wumubiri nkinda, imiti yibasira kanseri ya kanseri muri utwo turere (chimiotherapie yo mukarere). Uburyo chimiotherapie itangwa biterwa nubwoko nicyiciro cya kanseri ivurwa. Imiti ya chimiotherapie ni imiti ikoresheje imiti irenze imwe ya anticancer.

Reba Ibiyobyabwenge Byemewe kuri Myeloproliferative Neoplasms kubindi bisobanuro.

Ubundi buryo bwo kuvura ibiyobyabwenge

13-cis retinoic aside ni imiti isa na vitamine itinda ubushobozi bwa kanseri yo gukora kanseri nyinshi kandi igahindura uburyo izo selile zisa kandi zikora.

Gutera ingirabuzimafatizo

Chimiotherapie itangwa kugirango yice selile zidasanzwe cyangwa selile kanseri. Ingirabuzimafatizo nzima, harimo na selile zikora amaraso, nazo zirasenywa no kuvura kanseri. Gutera ingirabuzimafatizo ni uburyo bwo gusimbuza ingirabuzimafatizo. Ingirabuzimafatizo (selile zidakuze) zivanwa mumaraso cyangwa igufwa ryumurwayi cyangwa umuterankunga hanyuma bikonjeshwa bikabikwa. Nyuma yuko umurwayi arangije chimiotherapie, ingirangingo zibitswe zabitswe kandi zisubizwa umurwayi binyuze mu gushiramo. Izi ngirabuzimafatizo zongeye gukoreshwa zikura (kandi zigarura) ingirangingo z'amaraso z'umubiri.

Gutera ingirabuzimafatizo. (Intambwe ya 1): Amaraso yakuwe mumitsi mumaboko yumuterankunga. Umurwayi cyangwa undi muntu ashobora kuba umuterankunga. Amaraso atembera mumashini ikuraho ingirabuzimafatizo. Noneho amaraso asubizwa abaterankunga binyuze mumitsi mumaboko yandi. (Intambwe ya 2): Umurwayi yakira chimiotherapie kugirango yice selile zikora amaraso. Umurwayi arashobora guhabwa imiti ivura imirasire (iterekanwa). (Intambwe ya 3): Umurwayi yakira ingirabuzimafatizo binyuze muri catheter yashyizwe mu maraso mu gituza.

Kwitaho ubufasha

Hitaweho ubufasha bugamije kugabanya ibibazo biterwa n'indwara cyangwa kuyivura. Ubuvuzi bufasha bushobora kuba bukubiyemo guterwa amaraso cyangwa kuvura imiti, nka antibiotike yo kurwanya indwara.

Ubuvuzi bugamije

Ubuvuzi bugamije ni ubuvuzi bwa kanseri bukoresha ibiyobyabwenge cyangwa ibindi bintu byibasira kanseri ya kanseri bitangiza ingirabuzimafatizo zisanzwe. Imiti igamije kuvura yitwa tyrosine kinase inhibitor (TKIs) ikoreshwa mu kuvura myelodysplastic / myeloproliferative neoplasm, idasobanutse. TKIs ihagarika enzyme, tyrosine kinase, itera ingirabuzimafatizo kuba selile nyinshi (guturika) kuruta umubiri ukeneye. Imatinib mesylate (Gleevec) ni TKI ishobora gukoreshwa. Indi miti igamije kuvura irimo kwigwa mu kuvura JMML.

Reba Ibiyobyabwenge Byemewe kuri Myeloproliferative Neoplasms kubindi bisobanuro.

Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.

Amakuru yerekeye ibizamini byamavuriro araboneka kurubuga rwa NCI.

Umuti wa myelodysplastic / myeloproliferative neoplasms irashobora gutera ingaruka.

Kumakuru yingaruka ziterwa no kuvura kanseri, reba urupapuro rwuruhande rwacu.

Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.

Ku barwayi bamwe, kwitabira ikizamini cyamavuriro birashobora kuba uburyo bwiza bwo kuvura. Ibigeragezo bivura biri mubikorwa byubushakashatsi bwa kanseri. Igeragezwa rya Clinical rikorwa kugirango hamenyekane niba imiti mishya ya kanseri itekanye kandi ifite akamaro cyangwa nziza kuruta ubuvuzi busanzwe.

Benshi mubuvuzi busanzwe bwa kanseri bushingiye kubigeragezo byambere byubuvuzi. Abarwayi bitabiriye kwipimisha barashobora kuvurwa bisanzwe cyangwa kuba mubambere bahawe imiti mishya.

Abarwayi bitabira ibizamini byo kwa muganga nabo bafasha kunoza uburyo kanseri izavurwa mugihe kizaza. Nubwo ibigeragezo bivura bitaganisha ku buvuzi bushya, akenshi basubiza ibibazo byingenzi kandi bigafasha gutera imbere ubushakashatsi.

Abarwayi barashobora kwipimisha kwa muganga mbere, mugihe, cyangwa nyuma yo gutangira kuvura kanseri.

Igeragezwa rimwe na rimwe ririmo abarwayi bataravurwa. Ibindi bigeragezo bipima abarwayi bafite kanseri itameze neza. Hariho kandi ibizamini byo kwa muganga bipima uburyo bushya bwo guhagarika kanseri kongera kugaruka (kugaruka) cyangwa kugabanya ingaruka zo kuvura kanseri.

Igeragezwa rya Clinical ririmo kubera mu bice byinshi by'igihugu. Amakuru yerekeye ibizamini byamavuriro ashyigikiwe na NCI urashobora kubisanga kurubuga rwa NCI. Ibizamini bya Clinical bishyigikiwe nandi mashyirahamwe murashobora kubisanga kurubuga rwa ClinicalTrials.gov.

Ibizamini byo gukurikirana birashobora gukenerwa.

Bimwe mubizamini byakozwe mugupima kanseri cyangwa kumenya icyiciro cya kanseri birashobora gusubirwamo. Ibizamini bimwe bizasubirwamo kugirango harebwe uburyo ubuvuzi bukora neza. Ibyemezo bijyanye no gukomeza, guhindura, cyangwa guhagarika ubuvuzi birashobora gushingira kubisubizo byibi bizamini.

Bimwe mubizamini bizakomeza gukorwa buri gihe nyuma yubuvuzi burangiye. Ibisubizo by'ibi bizamini birashobora kwerekana niba ubuzima bwawe bwarahindutse cyangwa niba kanseri yarongeye (garuka). Ibi bizamini rimwe na rimwe byitwa gukurikirana-ibizamini cyangwa kugenzura.

Amahitamo yo kuvura Myelodysplastic / Myeloproliferative Neoplasms

Muri iki gice

• Indwara ya Myelomonocytic idakira

• Umwana muto Myelomonocytic Leukemia

• Indwara idasanzwe ya Myelogenous Leukemia

• Myelodysplastic / Myeloproliferative Neoplasm, Ntibishobora

Kumakuru yerekeye imiti yavuzwe hepfo, reba igice cyo kuvura.

Indwara ya Myelomonocytic idakira

Kuvura indwara ya myelomonocytic idakira (CMML) irashobora kuba ikubiyemo ibi bikurikira:

• Chimiotherapie hamwe numukozi umwe cyangwa benshi.

• Gutera ingirabuzimafatizo.

• Ikigeragezo cyamavuriro yubuvuzi bushya.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Umwana muto Myelomonocytic Leukemia

Kuvura indwara ya myelomonocytic leukemia (JMML) irashobora kuba ikubiyemo ibi bikurikira:

• Ubuvuzi bwa chimiotherapie.

• Gutera ingirabuzimafatizo.

• 13-cis-retinoic aside ivura.

• Ikigeragezo cyamavuriro yubuvuzi bushya, nkubuvuzi bugamije.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Indwara idasanzwe ya Myelogenous Leukemia

Umuti udasanzwe udasanzwe wa myelogenous leukemia (CML) urashobora kubamo chimiotherapie.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Myelodysplastic / Myeloproliferative Neoplasm, Ntibishobora

Kuberako myelodysplastic / myeloproliferative neoplasm, idashobora kwemerwa (MDS / MPN-UC) nindwara idasanzwe, bike bizwi kubijyanye no kuyivura. Ubuvuzi bushobora kubamo ibi bikurikira:

• Ubuvuzi bufasha bwo gukemura ibibazo biterwa n'indwara nko kwandura, kuva amaraso, no kubura amaraso.

• Ubuvuzi bugamije (imatinib mesylate).

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Kumenya byinshi kuri Myelodysplastic / Myeloproliferative Neoplasms

Ushaka amakuru menshi yikigo cyigihugu cya kanseri kubyerekeye myelodysplastic / myeloproliferative neoplasms, reba ibi bikurikira:

• Myeloproliferative Neoplasms Urupapuro rwurugo

• Gutera Amaraso Yimitsi Yimitsi

• Ibiyobyabwenge Byemewe kuri Myeloproliferative Neoplasms

• Intego zo kuvura Kanseri

Kumakuru rusange ya kanseri nibindi bikoresho biva mu kigo cyigihugu cya kanseri, reba ibi bikurikira:

• Ibyerekeye Kanseri

• Gutegura

• Chimiotherapie nawe: Inkunga kubantu barwaye Kanseri

• Ubuvuzi bwimirasire nawe: Inkunga kubantu barwaye Kanseri

• Guhangana na Kanseri

• Ibibazo byo Kubaza Muganga wawe kuri Kanseri

• Abacitse ku icumu n'abarezi