Ubwoko / lymphoma / umurwayi / primaire-cns-lymphoma-kuvura-pdq

Ubuvuzi bwibanze bwa CNS Lymphoma (®) - Indwara yabarwayi

Amakuru Rusange Yerekeye Ibyingenzi CNS Lymphoma

INGINGO Z'INGENZI

• Lymphoma yibanze ya santrale yibanze (CNS) ni indwara aho ingirabuzimafatizo (kanseri) ziba mu ngingo ya lymph tissue y'ubwonko na / cyangwa uruti rw'umugongo.

• Kugira ubudahangarwa bw'umubiri birashobora kongera ibyago byo kurwara lymphoma y'ibanze ya CNS.

• Ibizamini bisuzuma amaso, ubwonko, nu mugongo bikoreshwa mugushakisha (gushakisha) no gusuzuma lymphoma yibanze.

• Ibintu bimwe bigira ingaruka kubitekerezo (amahirwe yo gukira) hamwe nuburyo bwo kuvura.

Lymphoma yibanze ya santrale yibanze (CNS) ni indwara aho ingirabuzimafatizo (kanseri) ziba mu ngingo ya lymph tissue y'ubwonko na / cyangwa uruti rw'umugongo.

Lymphoma n'indwara ingirabuzimafatizo (kanseri) zikora muri sisitemu ya lymph. Sisitemu ya lymph igizwe na sisitemu yubudahangarwa kandi igizwe na lymph, imiyoboro ya lymph, node ya lymph, spleen, thymus, toniilles, na magufa. Lymphocytes (itwarwa muri lymph) igenda no hanze ya sisitemu yo hagati (CNS). Bikekwa ko zimwe murizo lymphocytes ziba mbi kandi zigatera lymphoma gukora muri CNS. Lymphoma yibanze ya CNS irashobora gutangirira mubwonko, uruti rw'umugongo, cyangwa meninges (ibice bigize igifuniko cyo hanze cyubwonko). Kubera ko ijisho ryegereye ubwonko, lymphoma y'ibanze ya CNS nayo ishobora gutangirira mu jisho (bita ocular lymphoma).

Anatomy ya sisitemu ya lymph, yerekana imiyoboro ya lymph ningingo zirimo lymph node, toni, tymus, spleen, hamwe namagufa. Lymph (fluid fluid) na lymphocytes zinyura mumitsi ya lymph no mumitsi ya lymphcytes aho lymphocytes zangiza ibintu byangiza. Lymph yinjira mumaraso binyuze mumitsi minini hafi yumutima.

Kugira ubudahangarwa bw'umubiri birashobora kongera ibyago byo kurwara lymphoma y'ibanze ya CNS.

Ikintu cyose cyongera amahirwe yo kwandura indwara cyitwa impanuka. Kugira ibintu bishobora guteza ibyago ntibisobanura ko uzarwara kanseri; kutagira ibyago bishobora gusobanura ko utazarwara kanseri. Vugana na muganga wawe niba utekereza ko ushobora guhura n'akaga.

Lymphoma y'ibanze ya CNS irashobora kugaragara kubarwayi barwaye syndrome de immunodeficiency (sida) cyangwa izindi ndwara ziterwa na sisitemu yumubiri cyangwa batewe impyiko. Ukeneye ibisobanuro birambuye kuri lymphoma ku barwayi barwaye sida, reba incamake ya ku kuvura Lymphoma bijyanye na sida.

Ibizamini bisuzuma amaso, ubwonko, nu mugongo bikoreshwa mugushakisha (gushakisha) no gusuzuma lymphoma yibanze.

Ibizamini hamwe nuburyo bukurikira birashobora gukoreshwa:

• Ikizamini cyumubiri namateka: Ikizamini cyumubiri kugirango ugenzure ibimenyetso rusange byubuzima, harimo no gusuzuma ibimenyetso byindwara, nkibibyimba cyangwa ikindi kintu cyose gisa nkidasanzwe. Hazafatwa kandi amateka yubuzima bwumurwayi nindwara zashize hamwe nubuvuzi.

• Ikizamini cya Neurologiya: Urukurikirane rwibibazo n'ibizamini byo gusuzuma ubwonko, uruti rw'umugongo, n'imikorere y'imitsi. Ikizamini kigenzura imiterere yumuntu, guhuza, ubushobozi bwo kugenda bisanzwe, nuburyo imitsi, ibyumviro, na refleks bikora. Ibi birashobora kandi kwitwa ikizamini cya neuro cyangwa ikizamini cya neurologic.

• Ikizamini cy'amaso ya slit -lamp: Ikizamini gikoresha microscope idasanzwe ifite urumuri rwinshi, rugufi rw'urumuri kugirango urebe hanze n'imbere y'ijisho.

• MRI . Ikintu cyitwa gadolinium cyatewe mumurwayi binyuze mumitsi. Gadolinium ikusanyiriza hafi ya kanseri ya kanseri kugirango igaragare neza ku ishusho. Ubu buryo bwitwa kandi magnetic magnetic resonance imaging (NMRI).

• PET scan (positron emission tomografi scan): Uburyo bwo kubona selile mbi yibibyimba mumubiri. Umubare muto wa glucose ikora radio (isukari) yatewe mumitsi. PET scaneri izenguruka umubiri kandi ikora ishusho yerekana aho glucose ikoreshwa mumubiri. Utugingo ngengabuzima twibibyimba twerekana neza cyane ku ishusho kuko zikora cyane kandi zifata glucose nyinshi kuruta selile zisanzwe.

• Gutobora Lumbar: Uburyo bukoreshwa mu gukusanya amazi ya cerebrospinal fluid (CSF) kuva kumugongo. Ibi bikorwa mugushira urushinge hagati yamagufa abiri murugongo no muri CSF ikikije uruti rwumugongo no gukuramo icyitegererezo cyamazi. Icyitegererezo cya CSF gisuzumwa munsi ya microscope kugirango ibimenyetso bya selile yibibyimba. Icyitegererezo gishobora kandi kugenzurwa ingano ya poroteyine na glucose. Umubare munini wa poroteyine cyangwa munsi ya glucose isanzwe irashobora kuba ikimenyetso cyikibyimba. Ubu buryo bwitwa LP cyangwa igikanda.

Gutobora. Umurwayi aryamye mumwanya uhetamye kumeza. Nyuma yumwanya muto kumugongo wo hasi ucecetse, urushinge rwumugongo (urushinge rurerure, ruto) rwinjizwa mubice byo hepfo yinkingi yumugongo kugirango rukureho ubwonko bwubwonko (CSF, bwerekanwe mubururu). Amazi arashobora koherezwa muri laboratoire kugirango isuzumwe.

• Stereotactique biopsy: Uburyo bwa biopsy bukoresha mudasobwa hamwe nicyuma cya 3-D (3-D) cyo gusikana kugirango kibone ikibyimba kandi kiyobore ikurwaho ryimyenda kugirango gishobore kurebwa munsi ya microscope kugirango hamenyekane ibimenyetso bya kanseri.

Ibizamini bikurikira birashobora gukorwa ku ngero za tissue zavanyweho:

• Flow cytometry: Ikizamini cya laboratoire gipima umubare w'utugingo ngengabuzima, ijanisha ry'utugingo ngengabuzima turi mu cyitegererezo, hamwe n'ibiranga ingirabuzimafatizo, nk'ubunini, imiterere, hamwe n'ibimenyetso by'ibibyimba (cyangwa ibindi) kuri Ubuso. Ingirabuzimafatizo ziva mu cyitegererezo cy'amaraso y'umurwayi, igufwa ry'amagufa, cyangwa izindi ngingo zandujwe irangi rya fluorescent, zishyirwa mu mazi, hanyuma zikanyura rimwe na rimwe binyuze mu rumuri. Ibisubizo by'ibizamini bishingiye ku kuntu ingirabuzimafatizo zandujwe irangi rya fluorescent zifata urumuri. Iki kizamini gikoreshwa mugufasha gusuzuma no gucunga ubwoko bumwe na bumwe bwa kanseri, nka leukemia na lymphoma.

• Immunohistochemie: Ikizamini cya laboratoire ikoresha antibodies kugirango igenzure antigene zimwe na zimwe (marikeri) mu cyitegererezo cyumubiri wumurwayi. Antibodies zisanzwe zifitanye isano na enzyme cyangwa irangi rya fluorescent. Antibodies zimaze guhuza antigen yihariye murugero rwa tissue, enzyme cyangwa irangi irakora, hanyuma antigen irashobora kuboneka munsi ya microscope. Ubu bwoko bwikizamini bukoreshwa mugufasha gusuzuma kanseri no gufasha kubwira ubwoko bumwe bwa kanseri buva mubundi bwoko bwa kanseri.

• Isesengura rya Cytogenetike: Ikizamini cya laboratoire aho chromosomes ya selile iri mu cyitegererezo cyamaraso cyangwa igufwa ryamagufwa ikabarwa kandi ikagenzurwa niba hari impinduka, nko kuvunika, kubura, gutondekanya, cyangwa chromosomes ziyongera. Impinduka muri chromosomes zimwe zishobora kuba ikimenyetso cya kanseri. Isesengura rya Cytogenetike rikoreshwa mu gufasha gusuzuma kanseri, gutegura gahunda yo kuvura, cyangwa kumenya uburyo ubuvuzi bukora neza.

• AMAFI (fluorescence in situ hybridisation): Ikizamini cya laboratoire ikoreshwa mu kureba no kubara gen cyangwa chromosomes mu ngirabuzimafatizo no mu ngingo. Ibice bya ADN birimo amarangi ya fluorescent bikozwe muri laboratoire hanyuma bikongerwaho icyitegererezo cy'uturemangingo cyangwa ingirangingo z'umurwayi. Iyo ibyo bice bisize irangi bya ADN bifatanye na genes cyangwa uduce twa chromosomes murugero, biramurika iyo urebye munsi ya microscope ya fluorescent. Ikizamini cya FISH gikoreshwa mugufasha gusuzuma kanseri no gufasha kuvura.

• Umubare wuzuye wamaraso (CBC) ufite itandukaniro: Uburyo bwo gukuramo urugero rwamaraso no gusuzuma ibi bikurikira:

• Umubare w'uturemangingo tw'amaraso atukura na platine.

• Umubare nubwoko bwingirangingo zamaraso yera.

• Ingano ya hemoglobine (proteyine itwara ogisijeni) mu ngirangingo z'amaraso atukura.

• Igice cyicyitegererezo cyamaraso kigizwe ningirabuzimafatizo zitukura.

Kubara amaraso yuzuye (CBC). Amaraso akusanywa no kwinjiza inshinge mumitsi no kwemerera amaraso gutembera mumiyoboro. Icyitegererezo cyamaraso cyoherezwa muri laboratoire hanyuma selile zitukura, selile yera, na platine zirabaze. CBC ikoreshwa mugupima, gusuzuma, no gukurikirana ibintu byinshi bitandukanye.

• Ubushakashatsi bwa chimie yamaraso: Uburyo bwo gusuzuma urugero rwamaraso kugirango bapime urugero rwibintu bimwe na bimwe bisohoka mumaraso ningingo nuduce twumubiri. Umubare udasanzwe (uri hejuru cyangwa uri munsi yubusanzwe) ibintu bishobora kuba ikimenyetso cyindwara.

Ibintu bimwe bigira ingaruka kubitekerezo (amahirwe yo gukira) hamwe nuburyo bwo kuvura.

Kumenyekanisha (amahirwe yo gukira) biterwa nibi bikurikira:

• Imyaka yumurwayi nubuzima rusange.

• Urwego rwibintu bimwe na bimwe mumaraso hamwe nubwonko bwubwonko (CSF).

• Aho ikibyimba kiri muri sisitemu yo hagati, ijisho, cyangwa byombi.

• Niba umurwayi afite sida.

Uburyo bwo kuvura buterwa nibi bikurikira:

• Intambwe ya kanseri.

• Aho ikibyimba kiri muri sisitemu yo hagati.

• Imyaka yumurwayi nubuzima rusange.

• Niba kanseri imaze gupimwa cyangwa yagarutse (garuka).

Kuvura lymphoma y'ibanze ya CNS ikora neza mugihe ikibyimba kitakwirakwiriye hanze yubwonko (igice kinini cyubwonko) kandi umurwayi akaba arengeje imyaka 60, ashobora gukora ibikorwa byinshi bya buri munsi, kandi akaba adafite sida cyangwa izindi ndwara ko guca intege umubiri.

Gutegura Ibanze CNS Lymphoma

INGINGO Z'INGENZI

• Nyuma yo gusuzuma indwara ya lymphoma yibanze yo hagati (CNS), hakozwe ibizamini kugirango hamenyekane niba selile kanseri yakwirakwiriye mu bwonko no mu ruti rw'umugongo cyangwa mu bindi bice by'umubiri.

• Hariho uburyo butatu kanseri ikwirakwira mu mubiri.

• Kanseri irashobora gukwirakwira aho yatangiriye no mu bindi bice byumubiri.

• Nta sisitemu isanzwe yo kubika lymphoma y'ibanze ya CNS.

Nyuma yo gusuzuma indwara ya lymphoma yibanze yo hagati (CNS), hakozwe ibizamini kugirango hamenyekane niba selile kanseri yakwirakwiriye mu bwonko no mu ruti rw'umugongo cyangwa mu bindi bice by'umubiri.

Iyo lymphoma yibanze ya CNS ikomeje gukura, mubisanzwe ntabwo ikwirakwira hejuru yimitsi yo hagati cyangwa ijisho. Inzira ikoreshwa mukumenya niba kanseri yarakwirakwijwe yitwa stage. Ni ngombwa kumenya niba kanseri yarakwirakwiriye mu bindi bice by'umubiri hagamijwe gutegura imiti. Ibizamini hamwe nuburyo bukurikira birashobora gukoreshwa mugutegura:

• CT scan (CAT scan): Uburyo bukora urukurikirane rwamashusho arambuye yibice byimbere mumubiri, byafashwe muburyo butandukanye. Amashusho yakozwe na mudasobwa ihujwe na mashini ya x-ray. Irangi rishobora guterwa mumitsi cyangwa kumirwa kugirango bifashe ingingo cyangwa ingirangingo kugaragara neza. Ubu buryo kandi bwitwa computing tomografiya, tomografiya ya mudasobwa, cyangwa mudasobwa ya axial tomografiya. Kuri lymphoma yibanze ya CNS, CT scan ikorwa mugituza, inda, na pelvis (igice cyumubiri hagati yibibuno).

• PET scan (positron emission tomografi scan): Uburyo bwo kubona selile mbi yibibyimba mumubiri. Umubare muto wa glucose ikora radio (isukari) yatewe mumitsi. PET scaneri izenguruka umubiri kandi ikora ishusho yerekana aho glucose ikoreshwa mumubiri. Utugingo ngengabuzima twibibyimba twerekana neza cyane ku ishusho kuko zikora cyane kandi zifata glucose nyinshi kuruta selile zisanzwe. PET scan na CT scan irashobora gukorwa mugihe kimwe. Ibi byitwa PET-CT.

• MRI . Ubu buryo bwitwa kandi magnetic magnetic resonance imaging (NMRI).

• Amagufa ya marrow aspiration na biopsy: Gukuraho igufwa ryamagufa, amaraso, nigice gito cyamagufwa winjiza urushinge rudafite epfo na ruguru cyangwa amabere. Inzobere mu by'indwara ireba amagufwa, amaraso, n'amagufwa munsi ya microscope kugira ngo ishakishe ibimenyetso bya kanseri.

Amagufa ya marrow icyifuzo na biopsy. Nyuma yuko agace gato k'uruhu kamaze kunanirwa, urushinge rw'amagufwa rwinjizwa mu igufwa ry'umurwayi. Ingero z'amaraso, amagufwa, n'amagufwa byavanyweho kugirango bisuzumwe kuri microscope.

Hariho uburyo butatu kanseri ikwirakwira mu mubiri.

Kanseri irashobora gukwirakwira binyuze mu ngingo, sisitemu ya lymph, n'amaraso:

• Tissue. Kanseri ikwirakwira aho yatangiriye ikurira mu turere twegereye.

• Sisitemu ya Lymph. Kanseri ikwirakwira aho yatangiriye yinjira muri sisitemu ya lymph. Kanseri inyura mu mitsi ya lymph igana mu bindi bice by'umubiri.

• Amaraso. Kanseri ikwirakwira aho yatangiriye yinjira mu maraso. Kanseri inyura mu mitsi y'amaraso igana mu bindi bice by'umubiri.

Kanseri irashobora gukwirakwira aho yatangiriye no mu bindi bice byumubiri.

Iyo kanseri ikwirakwira mu kindi gice cy'umubiri, yitwa metastasis. Ingirabuzimafatizo za kanseri zitandukana aho zatangiriye (ikibyimba kibanza) zikanyura muri sisitemu ya lymph cyangwa maraso.

• Sisitemu ya Lymph. Kanseri yinjira muri sisitemu ya lymph, ikanyura mu mitsi ya lymph, igakora ikibyimba (ikibyimba metastatike) mu kindi gice cy'umubiri.

• Amaraso. Kanseri yinjira mu maraso, ikanyura mu mitsi y'amaraso, igakora ikibyimba (ikibyimba metastatike) mu kindi gice cy'umubiri.

Ikibyimba metastatike nubwoko bumwe bwa kanseri nkibibyimba byibanze. Kurugero, niba lymphoma yibanze ya CNS ikwirakwira mu mwijima, kanseri ya kanseri mu mwijima ni selile lymphoma. Indwara ni lymphoma ya CNS metastatike, ntabwo ari kanseri y'umwijima.

Nta sisitemu isanzwe yo kubika lymphoma y'ibanze ya CNS.

Gusubiramo Ibanze CNS Lymphoma

Lymphoma yibanze ya santrale yibanze (CNS) ni kanseri yagarutse (garuka) nyuma yo kuvurwa. Lymphoma yibanze ya CNS ikunze kugaruka mubwonko cyangwa ijisho.

Incamake yo kuvura

INGINGO Z'INGENZI

• Hariho uburyo butandukanye bwo kuvura abarwayi bafite lymphoma yibanze.

• Uburyo butatu bwo kuvura bukoreshwa:

• Imiti ivura imirasire

• Chimoterapi

• Ubuvuzi bwa Steroid

• Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.

• Imiti myinshi ya chimiotherapie hamwe no guterwa ingirabuzimafatizo

• Ubuvuzi bugamije

• Umuti wa lymphoma yibanze ya CNS urashobora gutera ingaruka mbi.

• Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.

• Abarwayi barashobora kwipimisha kwa muganga mbere, mugihe, cyangwa nyuma yo gutangira kuvura kanseri.

• Ibizamini byo gukurikirana birashobora gukenerwa.

Hariho uburyo butandukanye bwo kuvura abarwayi bafite lymphoma yibanze.

Ubwoko butandukanye bwo kuvura buraboneka kubarwayi bafite lymphoma yibanze ya sisitemu yo hagati (CNS). Bumwe mu buryo busanzwe (ubuvuzi bukoreshwa ubu), kandi bumwe burimo kugeragezwa mubigeragezo byamavuriro. Ikigeragezo kivura ni ubushakashatsi bwakozwe bugamije gufasha kunoza imiti igezweho cyangwa kubona amakuru ku buvuzi bushya ku barwayi ba kanseri. Iyo ibizamini byo kwa muganga byerekana ko ubuvuzi bushya buruta ubuvuzi busanzwe, ubuvuzi bushya bushobora kuba ubuvuzi busanzwe. Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga. Ibigeragezo bimwe na bimwe bivura abarwayi batatangiye kwivuza.

Kubaga ntibikoreshwa mu kuvura lymphoma y'ibanze ya CNS.

Uburyo butatu bwo kuvura bukoreshwa:

Imiti ivura imirasire

Imishwarara ivura ni imiti ikoresha kanseri ikoresha ingufu nyinshi za x-imirasire cyangwa ubundi bwoko bwimirasire yica kanseri cyangwa ikabuza gukura. Hariho ubwoko bubiri bwo kuvura imirasire:

• Imiti ivura hanze ikoresha imashini hanze yumubiri kugirango yohereze imirasire kuri kanseri. Kubera ko lymphoma yibanze ikwirakwira mu bwonko, imiti ivura imirasire yo hanze ihabwa ubwonko bwose. Ibi byitwa kuvura ubwonko bwose.

• Imiti ivura imbere ikoresha ibintu bifata radiyo bifunze inshinge, imbuto, insinga, cyangwa catheteri bishyirwa muri kanseri cyangwa hafi yayo.

Uburyo imiti ivura imirasire itangwa biterwa nuko umurwayi afite lymphoma yibanze ya CNS na sida. Imiti ivura hanze ikoreshwa mu kuvura lymphoma y'ibanze.

Ubuvuzi bukabije bwimirasire yubwonko burashobora kwangiza ingirangingo nzima kandi bigatera imvururu zishobora kugira ingaruka kubitekerezo, kwiga, gukemura ibibazo, kuvuga, gusoma, kwandika, no kwibuka. Igeragezwa rya Clinical ryagerageje gukoresha imiti ya chimiotherapie yonyine cyangwa mbere yo kuvura imirasire kugirango igabanye kwangirika kwingirangingo zubwonko nzima zibaho hakoreshejwe imiti ivura imirasire.

Chimoterapi

Chimiotherapie ni umuti wa kanseri ukoresha ibiyobyabwenge kugirango uhagarike imikurire ya kanseri, haba mu kwica selile cyangwa kubabuza gutandukana. Iyo chimiotherapie ifashwe numunwa cyangwa igaterwa mumitsi cyangwa imitsi, imiti yinjira mumaraso kandi irashobora kugera kanseri ya kanseri mumubiri (chimiotherapie sisitemu). Iyo chimiotherapie ishyizwe mumazi ya cerebrospinal fluid (intrathecal chimiotherapie), urugingo, cyangwa umwobo wumubiri nkinda, imiti yibasira kanseri ya kanseri muri utwo turere (chimiotherapie yo mukarere).

Uburyo chimiotherapie itangwa bivana nigihe ikibyimba kiri muri CNS cyangwa ijisho. Lymphoma yibanze ya CNS irashobora kuvurwa hakoreshejwe chimiotherapie sisitemu, chimiotherapie intrathecal na / cyangwa chimiotherapie intraventricular, aho imiti igabanya ubukana ishyirwa mumashanyarazi (cavites yuzuye amazi) yubwonko. Niba lymphoma y'ibanze ya CNS iboneka mu jisho, imiti igabanya ubukana yatewe mu buryo busekeje (ibintu bimeze nka jelly) imbere y'ijisho.

Imiti ya chimiotherapie. Imiti igabanya ubukana yatewe mu mwanya wa intrathecal, niwo mwanya ufite amazi yo mu bwonko (CSF, yerekanwe mu bururu). Hariho inzira ebyiri zitandukanye zo gukora ibi. Bumwe mu buryo, bwerekanwa mu gice cyo hejuru cy’ishusho, ni ugutera imiti mu kigega cya Ommaya (ikintu kimeze nk'ikizenga gishyirwa munsi y’umutwe mu gihe cyo kubagwa; gifata imiti uko inyura mu muyoboro muto mu bwonko ). Ubundi buryo, bwerekanwe mugice cyo hasi cyigishushanyo, ni ugutera inshinge muri CSF mugice cyo hepfo yinkingi yumugongo, nyuma yumwanya muto kumugongo wo hasi ubuze.

Urusobe rw'imiyoboro y'amaraso hamwe na tissue, byitwa inzitizi y'amaraso-ubwonko, birinda ubwonko ibintu byangiza. Iyi bariyeri irashobora kandi gutuma imiti igabanya ubukana itagera mu bwonko. Mu rwego rwo kuvura lymphoma ya CNS, imiti imwe n'imwe irashobora gukoreshwa mu gufungura ingirabuzimafatizo ziri mu nzitizi y'amaraso n'ubwonko. Ibi byitwa guhagarika ubwonko bwamaraso. Imiti igabanya ubukana yinjiye mu maraso irashobora kugera mu bwonko.

Ubuvuzi bwa Steroid

Steroide ni imisemburo ikorwa bisanzwe mumubiri. Birashobora kandi gukorwa muri laboratoire bigakoreshwa nkibiyobyabwenge. Glucocorticoide ni imiti ya steroid igira anticancer muri lymphoma.

Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.

Iki gice cyincamake gisobanura imiti irimo kwigwa mubigeragezo byamavuriro. Ntishobora kuvuga ubuvuzi bushya burimo kwigwa. Amakuru yerekeye ibizamini byamavuriro araboneka kurubuga rwa NCI.

Imiti myinshi ya chimiotherapie hamwe no guterwa ingirabuzimafatizo

Umubare munini wa chimiotherapie utangwa kugirango wice selile. Ingirabuzimafatizo nzima, harimo na selile zikora amaraso, nazo zirasenywa no kuvura kanseri. Gutera ingirabuzimafatizo ni uburyo bwo gusimbuza ingirabuzimafatizo. Ingirabuzimafatizo (selile zidakuze) zivanwa mumaraso cyangwa igufwa ryumurwayi cyangwa umuterankunga hanyuma bikonjeshwa bikabikwa. Nyuma yuko umurwayi arangije chimiotherapie, ingirangingo zibitswe zabitswe kandi zisubizwa umurwayi binyuze mu gushiramo. Izi ngirabuzimafatizo zongeye gukoreshwa zikura (kandi zigarura) ingirangingo z'amaraso z'umubiri.

Ubuvuzi bugamije

Ubuvuzi bugamije ni uburyo bwo kuvura bukoresha ibiyobyabwenge cyangwa ibindi bintu byibasira kanseri. Ubuvuzi bugamije ubusanzwe butera kwangirika kwingirabuzimafatizo zisanzwe kuruta chimiotherapie cyangwa imiti ivura imirasire. Ubuvuzi bwa antibody ya Monoclonal ni bumwe mu buryo bwo kuvura bugamije kwigwa mu kuvura lymphoma y'ibanze ya CNS.

Ubuvuzi bwa Monoclonal antibody nubuvuzi bwa kanseri bukoresha antibodies zakozwe muri laboratoire ziva mubwoko bumwe bwimikorere yumubiri. Iyi antibodies irashobora kumenya ibintu biri muri kanseri ya kanseri cyangwa ibintu bisanzwe bishobora gufasha kanseri gukura. Antibodiyite ifata ibintu kandi ikica selile ya kanseri, ikabuza gukura kwayo, cyangwa ikabuza gukwirakwira. Antibodiyite za Monoclonal zitangwa no gushiramo. Bashobora gukoreshwa bonyine cyangwa gutwara ibiyobyabwenge, uburozi, cyangwa ibikoresho bya radio bikoresha kanseri ya kanseri. Rituximab ni ubwoko bwa antibody ya monoclonal ikoreshwa mu kuvura lymphoma y'ibanze ya CNS imaze kuvurwa ku barwayi badafite sida.

Umuti wa lymphoma yibanze ya CNS urashobora gutera ingaruka mbi.

Kumakuru yingaruka ziterwa no kuvura kanseri, reba urupapuro rwuruhande rwacu.

Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.

Ku barwayi bamwe, kwitabira ikizamini cyamavuriro birashobora kuba uburyo bwiza bwo kuvura. Ibigeragezo bivura biri mubikorwa byubushakashatsi bwa kanseri. Igeragezwa rya Clinical rikorwa kugirango hamenyekane niba imiti mishya ya kanseri itekanye kandi ifite akamaro cyangwa nziza kuruta ubuvuzi busanzwe.

Benshi mubuvuzi busanzwe bwa kanseri bushingiye kubigeragezo byambere byubuvuzi. Abarwayi bitabiriye kwipimisha barashobora kuvurwa bisanzwe cyangwa kuba mubambere bahawe imiti mishya.

Abarwayi bitabira ibizamini byo kwa muganga nabo bafasha kunoza uburyo kanseri izavurwa mugihe kizaza. Nubwo ibigeragezo bivura bitaganisha ku buvuzi bushya, akenshi basubiza ibibazo byingenzi kandi bigafasha gutera imbere ubushakashatsi.

Abarwayi barashobora kwipimisha kwa muganga mbere, mugihe, cyangwa nyuma yo gutangira kuvura kanseri.

Igeragezwa rimwe na rimwe ririmo abarwayi bataravurwa. Ibindi bigeragezo bipima abarwayi bafite kanseri itameze neza. Hariho kandi ibizamini byo kwa muganga bipima uburyo bushya bwo guhagarika kanseri kongera kugaruka (kugaruka) cyangwa kugabanya ingaruka zo kuvura kanseri.

Igeragezwa rya Clinical ririmo kubera mu bice byinshi by'igihugu. Amakuru yerekeye ibizamini byamavuriro ashyigikiwe na NCI urashobora kubisanga kurubuga rwa NCI. Ibizamini bya Clinical bishyigikiwe nandi mashyirahamwe murashobora kubisanga kurubuga rwa ClinicalTrials.gov.

Ibizamini byo gukurikirana birashobora gukenerwa.

Bimwe mubizamini byakozwe mugupima kanseri cyangwa kumenya icyiciro cya kanseri birashobora gusubirwamo. Ibizamini bimwe bizasubirwamo kugirango harebwe uburyo ubuvuzi bukora neza. Ibyemezo bijyanye no gukomeza, guhindura, cyangwa guhagarika ubuvuzi birashobora gushingira kubisubizo byibi bizamini.

Bimwe mubizamini bizakomeza gukorwa buri gihe nyuma yubuvuzi burangiye. Ibisubizo by'ibi bizamini birashobora kwerekana niba ubuzima bwawe bwarahindutse cyangwa niba kanseri yarongeye (garuka). Ibi bizamini rimwe na rimwe byitwa gukurikirana-ibizamini cyangwa kugenzura.

Amahitamo yo kuvura Lymphoma yibanze

Muri iki gice

• Intangiriro ya CNS Lymphoma

• Lymphoma Yibanze

• Gusubiramo Ibanze CNS Lymphoma

Kumakuru yerekeye imiti yavuzwe hepfo, reba igice cyo kuvura.

Intangiriro ya CNS Lymphoma

Kuvura lymphoma yibanze ya sisitemu yo hagati (CNS) irashobora kuba ikubiyemo ibi bikurikira:

• Ubuvuzi bwimirasire yubwonko bwose.

• Chimoterapi.

• Chimiotherapie ikurikirwa no kuvura imirasire.

• Chimiotherapie hamwe nubuvuzi bugamije (rituximab) hakurikiraho imiti myinshi ya chimiotherapie hamwe no guterwa ingirangingo.

• Ikigeragezo cya clinique ya chimiotherapie ikabije hamwe na transplant stem selile.

• Igeragezwa rya clinique ya chimiotherapie ikabije hamwe nubuvuzi bugamije (rituximab), hamwe cyangwa bidafite insimburangingo ngengabuzima cyangwa imiti ivura ubwonko bwose.

Lymphoma Yibanze

Kuvura lymphoma y'ibanze irashobora kuba ikubiyemo ibi bikurikira:

• Chimiotherapie (intraocular cyangwa sisitemu).

• Ubuvuzi bwimirasire yubwonko bwose.

Gusubiramo Ibanze CNS Lymphoma

Kuvura lymphoma yibanze ya santrale yibanze (CNS) bishobora kuba bikubiyemo ibi bikurikira:

• Chimoterapi.

• Ubuvuzi bwimirasire (niba butakiriwe mubuvuzi bwambere).

• Ikigeragezo kivura imiti mishya cyangwa gahunda yo kuvura.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Kugira ngo Wige Byinshi Kubanza CNS Lymphoma

Ushaka amakuru menshi yikigo cyigihugu cya kanseri kubyerekeye lymphoma yibanze ya CNS, reba ibi bikurikira:

• Urupapuro rwa Lymphoma

Kumakuru rusange ya kanseri nibindi bikoresho biva mu kigo cyigihugu cya kanseri, reba ibi bikurikira:

• Ibyerekeye Kanseri

• Gutegura

• Chimiotherapie nawe: Inkunga kubantu barwaye Kanseri

• Ubuvuzi bwimirasire nawe: Inkunga kubantu barwaye Kanseri

• Guhangana na Kanseri

• Ibibazo byo Kubaza Muganga wawe kuri Kanseri

• Abacitse ku icumu n'abarezi