Ubwoko / lymphoma / umurwayi / ubufasha bujyanye-kuvura-pdq

Ubuvuzi bwa Lymphoma bujyanye na sida (®) - Indwara y'abarwayi

Amakuru Rusange Yerekeye Lymphoma

INGINGO Z'INGENZI

• Indwara ya lymphoma ifitanye isano na sida ni indwara ingirabuzimafatizo (kanseri) zikora muri sisitemu ya lymph y'abarwayi bafite syndrome de immunodeficiency (SIDA).

• Hariho ubwoko bwinshi bwa lymphoma.

• Ibimenyetso bya lymphoma ifitanye isano na sida harimo kugabanya ibiro, umuriro, no kubira ibyuya nijoro.

• Ibizamini bisuzuma sisitemu ya lymph nibindi bice byumubiri bikoreshwa mugufasha kumenya (gushakisha) no gusuzuma lymphoma iterwa na sida.

• Ibintu bimwe bigira ingaruka kubitekerezo (amahirwe yo gukira) hamwe nuburyo bwo kuvura.

Indwara ya lymphoma ifitanye isano na sida ni indwara ingirabuzimafatizo (kanseri) zikora muri sisitemu ya lymph y'abarwayi bafite syndrome de immunodeficiency (SIDA).

SIDA iterwa na virusi ya immunodeficiency ya muntu (VIH), yibasira kandi igabanya intege nke z'umubiri. Ubudahangarwa bw'umubiri ntibushobora kurwanya indwara n'indwara. Ababana na virusi itera sida bafite ibyago byinshi byo kwandura na lymphoma cyangwa ubundi bwoko bwa kanseri. Umuntu wanduye virusi itera sida nubwoko bumwe na bumwe bwanduye cyangwa kanseri, nka lymphoma, basuzumwa ko arwaye sida. Rimwe na rimwe, abantu basuzumwa na lymphoma na sida icyarimwe. Kumakuru yerekeye sida nubuvuzi bwayo, nyamuneka reba kurubuga rwa sida.

Lymphoma ifitanye isano na sida ni ubwoko bwa kanseri yibasira sisitemu ya lymph. Sisitemu ya lymph igizwe na sisitemu yumubiri. Ifasha kurinda umubiri kwandura n'indwara.

Sisitemu ya lymph igizwe nibi bikurikira:

• Lymph: Amazi adafite ibara, amazi atembera mumitsi ya lymph kandi atwara lymphocytes T na B. Lymphocytes ni ubwoko bwamaraso yera.

• Imiyoboro ya Lymph: Urusobe rw'imiyoboro yoroheje ikusanya lymph mu bice bitandukanye by'umubiri ikayisubiza mu maraso.

• Indimu ya Lymph: Inzira ntoya, imeze nk'ibishyimbo iyungurura lymph kandi ikabika selile yera ifasha kurwanya indwara n'indwara. Indimu ya Lymph iboneka murusobe rwimitsi ya lymph umubiri wose. Amatsinda ya lymph node aboneka mu ijosi, munsi yintoki, mediastinum, inda, pelvis, no mugituba.

• Ururenda: Urugingo rukora lymphocytes, rukabika uturemangingo tw'amaraso atukura na lymphocytes, muyungurura amaraso, no gusenya uturemangingo twa kera. Ururenda ruri ku ruhande rw'ibumoso rw'inda hafi y'igifu.

• Thymus: Urugingo T lymphocytes T ikura ikagwira. Tymus iri mu gituza inyuma yigituza.

• Tonsil: Imbaga ebyiri ntoya ya lymph tissue inyuma yumuhogo. Hano hari toni imwe kuri buri ruhande rw'umuhogo.

• Amagufa yo mu magufa: Uturemangingo tworoshye, twinshi hagati yamagufwa amwe, nk'amagufwa yo mu kibuno ndetse n'igituza. Uturemangingo twamaraso yera, selile zitukura, na platine bikozwe mumagufwa.

Lymph tissue iboneka no mubindi bice byumubiri nkubwonko, igifu, glande ya tiroyide, nuruhu.

Rimwe na rimwe, lymphoma ifitanye isano na sida ibera hanze ya lymph node mu magufa, umwijima, meninges (membrane yoroheje itwikira ubwonko) hamwe na gastrointestinal tract. Kenshi na kenshi, birashobora kugaragara muri anus, umutima, umuyoboro wa bile, gingiva, n'imitsi.

Anatomy ya sisitemu ya lymph, yerekana imiyoboro ya lymph ningingo zirimo lymph node, toni, tymus, spleen, hamwe namagufa. Lymph (fluid fluid) na lymphocytes zinyura mumitsi ya lymph no mumitsi ya lymphcytes aho lymphocytes zangiza ibintu byangiza. Lymph yinjira mumaraso binyuze mumitsi minini hafi yumutima.

Hariho ubwoko bwinshi bwa lymphoma.

Lymphoma igabanijwemo ubwoko bubiri rusange:

• Lymphoma ya Hodgkin.

• Lymphoma itari Hodgkin.

Lymphoma itari Hodgkin na Lymphoma ya Hodgkin irashobora kugaragara ku barwayi ba sida, ariko lymphoma itari Hodgkin ikunze kugaragara. Iyo umuntu urwaye sida afite lymphoma itari Hodgkin, yitwa lymphoma ifitanye isano na sida. Iyo lymphoma ifitanye isano na sida iboneka muri sisitemu yo hagati (CNS), yitwa lymphoma yibanze ya sida.

Lymphoma itari Hodgkin yashyizwe hamwe nuburyo selile zabo zisa munsi ya microscope. Bashobora kuba badashaka (gukura-buhoro) cyangwa gutera (gukura-vuba). Lymphoma ifitanye isano na sida irakaze. Hariho ubwoko bubiri bwingenzi bwa sida iterwa na lymphoma itari Hodgkin:

• Gutandukanya lymphoma nini ya B-selile (harimo na B-selile immunoblastique lymphoma).

• Burkitt cyangwa Burkitt isa na lymphoma.

Ukeneye ibisobanuro birambuye kuri kanseri ya lymphoma cyangwa sida, reba incamake ya ikurikira:

• Abakuze Kuvura Lymphoma Ntabwo Hodgkin

• Umwana Kuvura Lymphoma Ntabwo Hodgkin

• Ubuvuzi bwibanze bwa CNS Lymphoma

• Umuti wa Kaposi Sarcoma

Ibimenyetso bya lymphoma ifitanye isano na sida harimo kugabanya ibiro, umuriro, no kubira ibyuya nijoro.

Ibi bimenyetso nibindi bimenyetso bishobora guterwa na lymphoma iterwa na sida cyangwa nibindi bihe. Menyesha umuganga wawe niba ufite kimwe muri ibi bikurikira:

• Kugabanya ibiro cyangwa umuriro nta mpamvu izwi.

• Ibyuya bya nijoro.

• Kubabara, kubyimba lymph node mu ijosi, mu gituza, munsi yintoki, cyangwa mugituba.

• Ibyiyumvo byuzuye munsi yimbavu.

Ibizamini bisuzuma sisitemu ya lymph nibindi bice byumubiri bikoreshwa mugufasha kumenya (gushakisha) no gusuzuma lymphoma iterwa na sida.

Ibizamini hamwe nuburyo bukurikira birashobora gukoreshwa:

• Ikizamini cyumubiri namateka: Ikizamini cyumubiri kugirango ugenzure ibimenyetso rusange byubuzima, harimo no gusuzuma ibimenyetso byindwara, nkibibyimba cyangwa ikindi kintu cyose gisa nkidasanzwe. Hazafatwa kandi amateka yubuzima bwumurwayi, harimo umuriro, ibyuya nijoro, no kugabanya ibiro, ingeso zubuzima, nindwara zashize hamwe nubuvuzi.

• Kubara amaraso yuzuye (CBC): Uburyo bwo gukuramo urugero rwamaraso no gusuzuma ibi bikurikira:

• Umubare w'uturemangingo tw'amaraso atukura, selile yera, na platine.

• Ingano ya hemoglobine (proteyine itwara ogisijeni) mu ngirangingo z'amaraso atukura.

• Igice cy'icyitegererezo kigizwe na selile zitukura.

Kubara amaraso yuzuye (CBC). Amaraso akusanywa no kwinjiza inshinge mumitsi no kwemerera amaraso gutembera mumiyoboro. Icyitegererezo cyamaraso cyoherezwa muri laboratoire hanyuma selile zitukura, selile yera, na platine zirabaze. CBC ikoreshwa mugupima, gusuzuma, no gukurikirana ibintu byinshi bitandukanye.

• Ubushakashatsi bwa chimie yamaraso: Uburyo bwo gusuzuma urugero rwamaraso kugirango bapime urugero rwibintu bimwe na bimwe bisohoka mumaraso ningingo nuduce twumubiri. Umubare udasanzwe (uri hejuru cyangwa uri munsi yubusanzwe) ibintu bishobora kuba ikimenyetso cyindwara.

• Ikizamini cya LDH: Uburyo bwo gusuzuma urugero rwamaraso kugirango bapime urugero rwa dehydrogenase ya lactique. Ubwiyongere bwa LDH mumaraso bushobora kuba ikimenyetso cyangirika kwinyama, lymphoma, cyangwa izindi ndwara.

• Ikizamini cya Hepatite B na hepatite C: Uburyo bwo gusuzuma urugero rwamaraso kugirango bapime ingano ya virusi yihariye ya virusi ya hepatite B na / cyangwa antibodi hamwe nubunini bwa virusi ya hepatite C. Izi antigene cyangwa antibodies bita marikeri. Ibimenyetso bitandukanye cyangwa guhuza ibimenyetso bikoreshwa kugirango hamenyekane niba umurwayi afite indwara ya hepatite B cyangwa C, yaba yaranduye mbere cyangwa inkingo, cyangwa ashobora kwandura.

• Kwipimisha virusi itera sida: Ikizamini cyo gupima urugero rwa antibodi ya virusi itera sida. Antibodies zikorwa numubiri iyo zatewe nibintu byamahanga. Urwego rwo hejuru rwa antibodiyite ya sida rushobora gusobanura ko umubiri wanduye virusi itera sida.

• CT scan (CAT scan): Uburyo bukora urukurikirane rwamashusho arambuye yibice byimbere mumubiri, nk'ijosi, igituza, inda, pelvis, na lymph node, byafashwe muburyo butandukanye. Amashusho yakozwe na mudasobwa ihujwe na mashini ya x-ray. Irangi rishobora guterwa mumitsi cyangwa kumirwa kugirango bifashe ingingo cyangwa ingirangingo kugaragara neza. Ubu buryo nabwo bwitwa computing tomografiya, tomografiya ya mudasobwa, cyangwa mudasobwa ya axial tomografiya.

• PET scan (positron emission tomografi scan): Uburyo bwo kubona selile mbi yibibyimba mumubiri. Umubare muto wa glucose ikora radio (isukari) yatewe mumitsi. PET scaneri izenguruka umubiri kandi ikora ishusho yerekana aho glucose ikoreshwa mumubiri. Utugingo ngengabuzima twibibyimba twerekana neza cyane ku ishusho kuko zikora cyane kandi zifata glucose nyinshi kuruta selile zisanzwe.

• Amagufa ya marrow aspiration na biopsy: Gukuraho igufwa ryamagufwa nigice gito cyamagufwa winjiza urushinge rufunitse mumatako cyangwa amabere. Inzobere mu by'indwara ireba igufwa n'amagufwa munsi ya microscope kugira ngo ishakishe ibimenyetso bya kanseri.

Amagufa ya marrow icyifuzo na biopsy. Nyuma yuko agace gato k'uruhu kamaze kunanirwa, urushinge rw'amagufwa rwinjizwa mu igufwa ry'umurwayi. Ingero z'amaraso, amagufwa, n'amagufwa byavanyweho kugirango bisuzumwe kuri microscope.

• Lymph node biopsy: Gukuraho ibintu byose cyangwa igice cya lymph node. Inzobere mu bijyanye n’indwara ireba ingirangingo ziri munsi ya microscope kugira ngo ishakishe kanseri. Bumwe mu bwoko bukurikira bwa biopsies burashobora gukorwa:

• Biopsy idasanzwe: Gukuraho lymph node yose.

• Biopsy incisional: Gukuraho igice cya lymph node.

• Core biopsy: Gukuraho tissue muri lymph node ukoresheje urushinge runini.

Ibindi bice byumubiri, nkumwijima, ibihaha, amagufwa, igufwa ryubwonko, nubwonko, birashobora kandi gukuramo urugero rwimitsi kandi bigasuzumwa numuhanga mubya patologue ibimenyetso bya kanseri.

Niba kanseri ibonetse, ibizamini bikurikira birashobora gukorwa kugirango bige kanseri ya kanseri:

• Immunohistochemie: Ikizamini cya laboratoire ikoresha antibodies kugirango igenzure antigene zimwe na zimwe (marikeri) mu cyitegererezo cyumubiri wumurwayi. Antibodies zisanzwe zifitanye isano na enzyme cyangwa irangi rya fluorescent. Antibodies zimaze guhuza antigen yihariye murugero rwa tissue, enzyme cyangwa irangi irakora, hanyuma antigen irashobora kuboneka munsi ya microscope. Ubu bwoko bw'ikizamini bukoreshwa mu gufasha gusuzuma kanseri no gufasha kubwira ubwoko bumwe bwa kanseri buva mu bundi bwoko bwa kanseri.

• Isesengura rya Cytogenetike: Ikizamini cya laboratoire aho chromosomes ya selile iri mu cyitegererezo cyamaraso cyangwa igufwa ryamagufwa ikabarwa kandi ikagenzurwa niba hari impinduka, nko kuvunika, kubura, gutondekanya, cyangwa chromosomes ziyongera. Impinduka muri chromosomes zimwe zishobora kuba ikimenyetso cya kanseri. Isesengura rya Cytogenetike rikoreshwa mu gufasha gusuzuma kanseri, gutegura gahunda yo kuvura, cyangwa kumenya uburyo ubuvuzi bukora neza.

• AMAFI (fluorescence in situ hybridisation): Ikizamini cya laboratoire ikoreshwa mu kureba no kubara gen cyangwa chromosomes mu ngirabuzimafatizo no mu ngingo. Ibice bya ADN birimo amarangi ya fluorescent bikozwe muri laboratoire hanyuma bikongerwaho icyitegererezo cy'uturemangingo cyangwa ingirangingo z'umurwayi. Iyo ibyo bice bisize irangi bya ADN bifatanye na genes cyangwa uduce twa chromosomes murugero, biramurika iyo urebye munsi ya microscope ya fluorescent. Ikizamini cya FISH gikoreshwa mugufasha gusuzuma kanseri no gufasha kuvura.

• Immunophenotyping: Ikizamini cya laboratoire ikoresha antibodies kugirango hamenyekane kanseri ya kanseri ukurikije ubwoko bwa antigene cyangwa ibimenyetso hejuru ya selile. Iki kizamini gikoreshwa mugufasha gusuzuma ubwoko bwihariye bwa lymphoma.

Ibintu bimwe bigira ingaruka kubitekerezo (amahirwe yo gukira) hamwe nuburyo bwo kuvura.

Kumenyekanisha (amahirwe yo gukira) hamwe nuburyo bwo kuvura biterwa nibi bikurikira:

• Intambwe ya kanseri.

• Imyaka yumurwayi.

• Umubare wa lymphocytes CD4 (ubwoko bwamaraso yera) mumaraso.

• Umubare wibibanza mumubiri lymphoma uboneka hanze ya lymph sisitemu.

• Niba umurwayi afite amateka yo gukoresha ibiyobyabwenge (IV).

• Ubushobozi bwumurwayi bwo gukora ibikorwa bisanzwe bya buri munsi.

Icyiciro cya Lymphoma ifitanye isano na sida

INGINGO Z'INGENZI

• Indwara ya lymphoma ifitanye isano na sida imaze gupimwa, hakorwa ibizamini kugira ngo hamenyekane niba kanseri ya kanseri yakwirakwiriye muri sisitemu ya lymph cyangwa mu bindi bice by'umubiri.

• Hariho uburyo butatu kanseri ikwirakwira mu mubiri.

• Ibyiciro bikurikira bikoreshwa kuri lymphoma iterwa na sida:

• Icyiciro I.

• Icyiciro cya II

• Icyiciro cya III

• Icyiciro cya IV

• Mu kuvura, lymphoma ziterwa na sida zishyizwe hamwe ukurikije aho zatangiriye mu mubiri, ku buryo bukurikira:

• Lymphoma ya periferique

• Lymphoma yibanze

Indwara ya lymphoma ifitanye isano na sida imaze gupimwa, hakorwa ibizamini kugira ngo hamenyekane niba kanseri ya kanseri yakwirakwiriye muri sisitemu ya lymph cyangwa mu bindi bice by'umubiri.

Inzira ikoreshwa mu kumenya niba selile ya kanseri yakwirakwiriye muri sisitemu ya lymph cyangwa mu bindi bice byumubiri byitwa guterana. Amakuru yakusanyirijwe mubikorwa byateguwe agena icyiciro cyindwara. Ni ngombwa kumenya icyiciro kugirango utegure ubuvuzi, ariko lymphoma iterwa na sida ikunze gutera imbere iyo isuzumwe.

Ibizamini hamwe nuburyo bukurikira birashobora gukoreshwa mugutegura:

• MRI . Ikintu cyitwa gadolinium cyatewe mumurwayi binyuze mumitsi. Gadolinium ikusanyiriza hafi ya kanseri ya kanseri kugirango igaragare neza ku ishusho. Ubu buryo bwitwa kandi magnetic magnetic resonance imaging (NMRI).

• Gutobora Lumbar: Uburyo bukoreshwa mu gukusanya amazi ya cerebrospinal fluid (CSF) kuva kumugongo. Ibi bikorwa mugushira urushinge hagati yamagufa abiri murugongo no muri CSF ikikije uruti rwumugongo no gukuramo icyitegererezo cyamazi. Icyitegererezo cya CSF gisuzumwa munsi ya microscope kugirango ibimenyetso byerekana ko kanseri yakwirakwiriye mu bwonko no mu ruti rw'umugongo. Icyitegererezo gishobora kandi gusuzumwa virusi ya Epstein-Barr. Ubu buryo bwitwa LP cyangwa igikanda.

Gutobora. Umurwayi aryamye mumwanya uhetamye kumeza. Nyuma yumwanya muto kumugongo wo hasi ucecetse, urushinge rwumugongo (urushinge rurerure, ruto) rwinjizwa mubice byo hepfo yinkingi yumugongo kugirango rukureho ubwonko bwubwonko (CSF, bwerekanwe mubururu). Amazi arashobora koherezwa muri laboratoire kugirango isuzumwe.

Hariho uburyo butatu kanseri ikwirakwira mu mubiri.

Kanseri irashobora gukwirakwira binyuze mu ngingo, sisitemu ya lymph, n'amaraso:

• Tissue. Kanseri ikwirakwira aho yatangiriye ikurira mu turere twegereye.

• Sisitemu ya Lymph. Kanseri ikwirakwira aho yatangiriye yinjira muri sisitemu ya lymph. Kanseri inyura mu mitsi ya lymph igana mu bindi bice by'umubiri.

• Amaraso. Kanseri ikwirakwira aho yatangiriye yinjira mu maraso. Kanseri inyura mu mitsi y'amaraso igana mu bindi bice by'umubiri.

Ibyiciro bikurikira bikoreshwa kuri lymphoma iterwa na sida:

Icyiciro I.

Icyiciro cya I lymphoma ikuze. Kanseri iboneka muri lymph node imwe cyangwa nyinshi mumatsinda ya lymph node, cyangwa, gake, kanseri iboneka mumpeta ya Waldeyer, thymus, cyangwa spleen. Mu cyiciro cya IE (kiterekanwa), kanseri yakwirakwiriye mu gace kamwe ka sisitemu ya lymph.

Icyiciro cya I lymphoma ifitanye isano na sida igabanyijemo ibyiciro I na IE.

• Mu cyiciro cya I, kanseri iboneka muri hamwe mu buryo bukurikira muri sisitemu ya lymph:

• Imwe cyangwa nyinshi ya lymph node mumatsinda ya lymph node.

• Impeta ya Waldeyer.

• Tymus.

• Intanga.

• Mu cyiciro cya IE, kanseri iboneka ahantu hamwe hanze ya sisitemu ya lymph.

• Icyiciro cya II

• Icyiciro cya II Lymphoma ifitanye isano na sida igabanyijemo ibyiciro II na IIE.

• Mu cyiciro cya II, kanseri iboneka mu matsinda abiri cyangwa menshi ya lymph node iri hejuru ya diafragma cyangwa munsi ya diafragma.

Icyiciro cya II lymphoma ikuze. Kanseri iboneka mu matsinda abiri cyangwa menshi ya lymph node iri hejuru ya diafragma cyangwa munsi ya diafragma.

• Mu cyiciro cya IIE, kanseri yakwirakwiriye mu itsinda rya lymph node kugera mu gace kegereye kari hanze ya sisitemu ya lymph. Kanseri irashobora gukwirakwira mu yandi matsinda ya lymph node kuruhande rumwe rwa diafragma.

Icyiciro cya IIE lymphoma ikuze. Kanseri yakwirakwiriye mu itsinda rya lymph node kugera ahantu hegereye hanze ya sisitemu ya lymph. Kanseri irashobora gukwirakwira mu yandi matsinda ya lymph node kuruhande rumwe rwa diafragma.

Mu cyiciro cya II, ijambo indwara nini ryerekeza ku mubyimba munini. Ingano yibibyimba byitwa indwara nini iratandukanye bitewe n'ubwoko bwa lymphoma.

Icyiciro cya III

Icyiciro cya III lymphoma ikuze. Kanseri iboneka mu matsinda ya lymph node haba hejuru no munsi ya diafragma; cyangwa mumatsinda ya lymph node hejuru ya diaphragm no mumutwe.

Mu cyiciro cya III lymphoma ifitanye isano na sida, kanseri iboneka:

• mu matsinda ya lymph node haba hejuru no munsi ya diafragma; cyangwa

• muri lymph node hejuru ya diaphragm no mumutwe.

Icyiciro cya IV

Icyiciro cya IV lymphoma ikuze. Kanseri (a) yakwirakwiriye mu ngingo imwe cyangwa nyinshi hanze ya sisitemu ya lymph; cyangwa (b) iboneka mu matsinda abiri cyangwa menshi ya lymph node iri hejuru ya diafragma cyangwa munsi ya diafragma no mu rugingo rumwe ruri hanze ya lymph kandi rutari hafi ya lymph node; cyangwa (c) iboneka mumatsinda ya lymph node hejuru ya diafragma no munsi ya diafragma no mubice byose biri hanze ya sisitemu ya lymph; cyangwa (d) iboneka mu mwijima, mu magufa, ahantu henshi mu bihaha, cyangwa mu bwonko bwa cerebrospinal (CSF). Kanseri ntiyakwirakwiriye mu mwijima, mu magufa, mu bihaha, cyangwa CSF kuva hafi ya lymph node.

Mu cyiciro cya IV lymphoma ifitanye isano na sida, kanseri:

• yakwirakwiriye mu ngingo imwe cyangwa nyinshi hanze ya lymph sisitemu; cyangwa

• iboneka mu matsinda abiri cyangwa menshi ya lymph node iri hejuru ya diafragma cyangwa munsi ya diafragma no mu rugingo rumwe ruri hanze ya lymph kandi rutari hafi ya lymph node; cyangwa

• iboneka mumatsinda ya lymph node haba hejuru no munsi ya diafragma no mubice byose biri hanze ya sisitemu ya lymph; cyangwa

• iboneka mu mwijima, mu magufa, ahantu henshi mu bihaha, cyangwa mu bwonko bwa cerebrospinal (CSF). Kanseri ntiyakwirakwiriye mu mwijima, mu magufa, mu bihaha, cyangwa CSF kuva hafi ya lymph node.

Abarwayi banduye virusi ya Epstein-Barr cyangwa lymphoma ifitanye isano na sida ifata igufwa ry'amagufwa bafite ibyago byinshi byo kwandura kanseri ikwirakwira muri sisitemu yo hagati (CNS).

Mu kuvura, lymphoma ziterwa na sida zishyizwe hamwe ukurikije aho zatangiriye mu mubiri, ku buryo bukurikira:

Lymphoma ya periferique

Lymphoma itangirira muri sisitemu ya lymph cyangwa ahandi mu mubiri, uretse ubwonko, yitwa lymphoma peripheral / sisitemu. Irashobora gukwirakwira mu mubiri, harimo no mu bwonko cyangwa mu magufa. Bikunze gusuzumwa murwego rwo hejuru.

Lymphoma yibanze

Lymphoma yibanze ya CNS itangirira muri sisitemu yo hagati (ubwonko nu mugongo). Ifitanye isano na virusi ya Epstein-Barr. Lymphoma itangirira ahandi mu mubiri ikwirakwira muri sisitemu yo hagati ntabwo ari lymphoma y'ibanze ya CNS.

Incamake yo kuvura

INGINGO Z'INGENZI

• Hariho uburyo butandukanye bwo kuvura abarwayi bafite lymphoma iterwa na sida.

• Kuvura lymphoma iterwa na sida bihuza kuvura lymphoma no kuvura sida.

• Ubwoko bune bwo kuvura busanzwe bukoreshwa:

• Chimoterapi

• Imiti ivura imirasire

• Imiti myinshi ya chimiotherapie hamwe no guterwa ingirabuzimafatizo

• Ubuvuzi bugamije

• Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.

• Umuti wa lymphoma ujyanye na sida urashobora gutera ingaruka.

• Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.

• Abarwayi barashobora kwipimisha kwa muganga mbere, mugihe, cyangwa nyuma yo gutangira kuvura kanseri.

• Ibizamini byo gukurikirana birashobora gukenerwa.

Hariho uburyo butandukanye bwo kuvura abarwayi bafite lymphoma iterwa na sida.

Ubwoko butandukanye bwo kuvura burahari kubarwayi barwaye lymphoma. Bumwe mu buryo busanzwe (ubuvuzi bukoreshwa ubu), kandi bumwe burimo kugeragezwa mubigeragezo byamavuriro. Ikigeragezo kivura ni ubushakashatsi bwakozwe bugamije gufasha kunoza imiti igezweho cyangwa kubona amakuru ku buvuzi bushya ku barwayi ba kanseri. Iyo ibizamini byo kwa muganga byerekana ko ubuvuzi bushya buruta ubuvuzi busanzwe, ubuvuzi bushya bushobora kuba ubuvuzi busanzwe. Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga. Ibigeragezo bimwe na bimwe bivura abarwayi batatangiye kwivuza.

Kuvura lymphoma iterwa na sida bihuza kuvura lymphoma no kuvura sida.

Abarwayi ba sida bagabanije ubudahangarwa bw'umubiri kandi kuvura birashobora gutuma ubudahangarwa bw'umubiri bugabanuka. Kubera iyo mpamvu, kuvura abarwayi bafite lymphoma iterwa na sida biragoye kandi abarwayi bamwe bashobora kuvurwa bafite imiti mike ugereranije n’abarwayi ba lymphoma badafite sida.

Ubuvuzi bukomeye bwa virusi itera SIDA (HAART) bukoreshwa mukugabanya kwangirika kwumubiri watewe na virusi itera sida. Umuti hamwe na HAART urashobora kwemerera abarwayi bamwe na bamwe bafite lymphoma iterwa na sida kwakira neza imiti igabanya ubukana bwa dosiye isanzwe cyangwa irenga. Muri aba barwayi, kuvura birashobora gukora neza nkuko bikora ku barwayi ba lymphoma badafite sida. Ubuvuzi bwo gukumira no kuvura indwara, zishobora kuba zikomeye, nabwo burakoreshwa.

Kubindi bisobanuro bijyanye na sida nubuvuzi bwayo, nyamuneka reba kurubuga rwa sida.

Ubwoko bune bwo kuvura busanzwe bukoreshwa:

Chimoterapi

Chimoterapi ni umuti wa kanseri ukoresha ibiyobyabwenge kugirango uhagarike imikurire ya kanseri, haba mu kwica selile cyangwa kubabuza gutandukana. Iyo chimiotherapie ifashwe numunwa cyangwa igaterwa mumitsi cyangwa imitsi, imiti yinjira mumaraso kandi irashobora kugera kanseri ya kanseri mumubiri (chimiotherapie sisitemu). Iyo chimiotherapie ishyizwe mumazi ya cerebrospinal fluid (intrathecal chimiotherapie), urugingo, cyangwa umwobo wumubiri nkinda, imiti yibasira cyane kanseri muri utwo turere (chimiotherapie yo mukarere). Imiti ya chimiotherapie ni imiti ikoresheje imiti irenze imwe ya anticancer.

Uburyo chimiotherapie itangwa biterwa na kanseri. Imiti ya chimiotherapie irashobora gukoreshwa mubarwayi bakunze kugira lymphoma muri sisitemu yo hagati (CNS).

Imiti ya chimiotherapie. Imiti igabanya ubukana yatewe mu mwanya wa intrathecal, niwo mwanya ufite amazi yo mu bwonko (CSF, yerekanwe mu bururu). Hariho inzira ebyiri zitandukanye zo gukora ibi. Bumwe mu buryo, bwerekanwa mu gice cyo hejuru cy’ishusho, ni ugutera imiti mu kigega cya Ommaya (ikintu kimeze nk'ikibumbano gishyirwa munsi y’umutwe mu gihe cyo kubagwa; gifata imiti uko inyura mu muyoboro muto mu bwonko ). Ubundi buryo, bwerekanwe mugice cyo hasi cyigishushanyo, ni ugutera inshinge muri CSF mugice cyo hepfo yinkingi yumugongo, nyuma yumwanya muto kumugongo wo hasi ubuze.

Chimoterapi ikoreshwa mukuvura sida ifitanye isano na sima ya lymphoma. Kugeza ubu ntiharamenyekana niba ari byiza guha HAART icyarimwe na chimiotherapie cyangwa nyuma ya chimiotherapie irangiye.

Ibintu bitera ubukoroni rimwe na rimwe bitangwa hamwe na chimiotherapie. Ibi bifasha kugabanya ingaruka mbi chimiotherapie ishobora kugira kumitsi.

Imiti ivura imirasire

Imishwarara ivura ni imiti ikoresha kanseri ikoresha ingufu nyinshi za x-imirasire cyangwa ubundi bwoko bwimirasire yica kanseri cyangwa ikabuza gukura. Hariho ubwoko bubiri bwo kuvura imirasire:

• Imiti ivura hanze ikoresha imashini hanze yumubiri kugirango yohereze imirasire kuri kanseri.

• Imiti ivura imbere ikoresha ibintu bifata radiyo bifunze inshinge, imbuto, insinga, cyangwa catheteri bishyirwa muri kanseri cyangwa hafi yayo.

Uburyo imiti ivura imirasire itangwa bivana na kanseri. Imiti ivura hanze ikoreshwa mu kuvura lymphoma yibanze ya sida.

Imiti myinshi ya chimiotherapie hamwe no guterwa ingirabuzimafatizo

Umubare munini wa chimiotherapie utangwa kugirango wice selile. Ingirabuzimafatizo nzima, harimo na selile zikora amaraso, nazo zirasenywa no kuvura kanseri. Gutera ingirabuzimafatizo ni uburyo bwo gusimbuza ingirabuzimafatizo. Ingirabuzimafatizo (selile yamaraso idakuze) ikurwa mumaraso cyangwa igufwa ryumurwayi kandi irakonja ikabikwa. Nyuma yuko umurwayi arangije chimiotherapie, ingirangingo zibitswe zabitswe kandi zisubizwa umurwayi binyuze mu gushiramo. Izi ngirabuzimafatizo zongeye gukoreshwa zikura (kandi zigarura) ingirangingo z'amaraso z'umubiri.

Ubuvuzi bugamije

Ubuvuzi bugamije ni uburyo bwo kuvura bukoresha ibiyobyabwenge cyangwa ibindi bintu kugirango umenye kandi utere kanseri yihariye ya kanseri utangiza ingirabuzimafatizo zisanzwe. Ubuvuzi bwa antibody ya Monoclonal ni ubwoko bwo kuvura bugamije.

Ubuvuzi bwa Monoclonal antibody nubuvuzi bwa kanseri bukoresha antibodies zakozwe muri laboratoire ziva mubwoko bumwe bwimikorere yumubiri. Iyi antibodies irashobora kumenya ibintu biri muri kanseri ya kanseri cyangwa ibintu bisanzwe bishobora gufasha kanseri gukura. Antibodiyite ifata ibintu kandi ikica selile ya kanseri, ikabuza gukura kwayo, cyangwa ikabuza gukwirakwira. Antibodiyite za Monoclonal zitangwa no gushiramo. Ibi birashobora gukoreshwa byonyine cyangwa gutwara ibiyobyabwenge, uburozi, cyangwa ibikoresho bya radio bikora kanseri ya kanseri. Rituximab ikoreshwa mukuvura sida ifitanye isano na sima ya lymphoma.

Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.

Amakuru yerekeye ibizamini byamavuriro araboneka kurubuga rwa NCI.

Umuti wa lymphoma ujyanye na sida urashobora gutera ingaruka.

Kumakuru yingaruka ziterwa no kuvura kanseri, reba urupapuro rwuruhande rwacu.

Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.

Ku barwayi bamwe, kwitabira ikizamini cyamavuriro birashobora kuba uburyo bwiza bwo kuvura. Ibigeragezo bivura biri mubikorwa byubushakashatsi bwa kanseri. Igeragezwa rya Clinical rikorwa kugirango hamenyekane niba imiti mishya ya kanseri itekanye kandi ifite akamaro cyangwa nziza kuruta ubuvuzi busanzwe.

Benshi mubuvuzi busanzwe bwa kanseri bushingiye kubigeragezo byambere byubuvuzi. Abarwayi bitabiriye kwipimisha barashobora kuvurwa bisanzwe cyangwa kuba mubambere bahawe imiti mishya.

Abarwayi bitabira ibizamini byo kwa muganga nabo bafasha kunoza uburyo kanseri izavurwa mugihe kizaza. Nubwo ibigeragezo bivura bitaganisha ku buvuzi bushya, akenshi basubiza ibibazo byingenzi kandi bigafasha gutera imbere ubushakashatsi.

Abarwayi barashobora kwipimisha kwa muganga mbere, mugihe, cyangwa nyuma yo gutangira kuvura kanseri.

Igeragezwa rimwe na rimwe ririmo abarwayi bataravurwa. Ibindi bigeragezo bipima abarwayi bafite kanseri itameze neza. Hariho kandi ibizamini byo kwa muganga bipima uburyo bushya bwo guhagarika kanseri kongera kugaruka (kugaruka) cyangwa kugabanya ingaruka zo kuvura kanseri.

Igeragezwa rya Clinical ririmo kubera mu bice byinshi by'igihugu. Amakuru yerekeye ibizamini byamavuriro ashyigikiwe na NCI urashobora kubisanga kurubuga rwa NCI. Ibizamini bya Clinical bishyigikiwe nandi mashyirahamwe murashobora kubisanga kurubuga rwa ClinicalTrials.gov.

Ibizamini byo gukurikirana birashobora gukenerwa.

Bimwe mubizamini byakozwe mugupima kanseri cyangwa kumenya icyiciro cya kanseri birashobora gusubirwamo. Ibizamini bimwe bizasubirwamo kugirango harebwe uburyo ubuvuzi bukora neza. Ibyemezo bijyanye no gukomeza, guhindura, cyangwa guhagarika ubuvuzi birashobora gushingira kubisubizo byibi bizamini.

Bimwe mubizamini bizakomeza gukorwa buri gihe nyuma yubuvuzi burangiye. Ibisubizo by'ibi bizamini birashobora kwerekana niba ubuzima bwawe bwarahindutse cyangwa niba kanseri yarongeye (garuka). Ibi bizamini rimwe na rimwe byitwa gukurikirana-ibizamini cyangwa kugenzura.

Uburyo bwo kuvura Lymphoma ifitanye isano na sida

Muri iki gice

• Indwara ya sida ifitanye isano na Lymphoma ya sisitemu

• Indwara ya sida yibanze ya sisitemu yo hagati ya Lymphoma

Kumakuru yerekeye imiti yavuzwe hepfo, reba igice cyo kuvura.

Indwara ya sida ifitanye isano na Lymphoma ya sisitemu

Kuvura sida ifitanye isano na sida / lymphoma sisitemu irashobora kuba ikubiyemo ibi bikurikira:

• Gukomatanya chimiotherapie hamwe nubuvuzi butagenewe.

• Imiti myinshi ya chimiotherapie hamwe na stem selile transplant, kuri lymphoma itigeze yitabira kuvurwa cyangwa yagarutse.

• Imiti ya chimiotherapie ya lymphoma ishobora gukwirakwira muri sisitemu yo hagati (CNS).

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Indwara ya sida yibanze ya sisitemu yo hagati ya Lymphoma

Umuti wa sima yibanze ya lymphoma yibanze ya sida irashobora kuba ikubiyemo ibi bikurikira:

• Ubuvuzi bwo hanze.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Kumenya byinshi kuri Lymphoma ifitanye isano na sida

Ushaka amakuru menshi yikigo cyigihugu cya kanseri kubyerekeye lymphoma iterwa na sida, reba ibi bikurikira:

• Gutera Amaraso Yimitsi Yimitsi

• Intego zo kuvura Kanseri

Kumakuru rusange ya kanseri nibindi bikoresho biva mu kigo cyigihugu cya kanseri, reba ibi bikurikira:

• Ibyerekeye Kanseri

• Gutegura

• Chimiotherapie nawe: Inkunga kubantu barwaye Kanseri

• Ubuvuzi bwimirasire nawe: Inkunga kubantu barwaye Kanseri

• Guhangana na Kanseri

• Ibibazo byo Kubaza Muganga wawe kuri Kanseri

• Abacitse ku icumu n'abarezi