Ubwoko / leukemia / umurwayi / umuntu mukuru-aml-kuvura-pdq

Abakuze Acute Myeloid Leukemia (?) - Version y'abarwayi

Amakuru Rusange Yerekeye Abakuze Acute Myeloid Leukemia

INGINGO Z'INGENZI

• Abakuze acute myeloid leukemia (AML) ni ubwoko bwa kanseri aho igufwa ryamagufa rikora myeloblasts idasanzwe (ubwoko bwamaraso yera), selile zitukura, cyangwa platine.

• Leukemia irashobora kwanduza selile zitukura, selile yera, na platine.

• Hariho ubwoko butandukanye bwa AML.

• Kunywa itabi, kuvura imiti ya chimiotherapie, hamwe no guhura nimirase bishobora kugira ingaruka kumuntu mukuru AML.

• Ibimenyetso nibimenyetso byabakuze AML harimo umuriro, kumva unaniwe, no gukomeretsa byoroshye cyangwa kuva amaraso.

• Ibizamini bisuzuma amaraso n'amagufa bikoreshwa mugushakisha (gushakisha) no gusuzuma AML ikuze.

• Ibintu bimwe bigira ingaruka kubitekerezo (amahirwe yo gukira) hamwe nuburyo bwo kuvura.

Abakuze acute myeloid leukemia (AML) ni ubwoko bwa kanseri aho igufwa ryamagufa rikora myeloblasts idasanzwe (ubwoko bwamaraso yera), selile zitukura, cyangwa platine.

Abakuze acute myeloid leukemia (AML) ni kanseri y'amaraso n'amagufa. Ubu bwoko bwa kanseri burakomera vuba iyo butavuwe. Nubwoko busanzwe bwa leukemia ikaze mubantu bakuru. AML nayo yitwa acute myelogenous leukemia, acute myeloblastic leukemia, acute granulocytic leukemia, na acute nonlymphocytic leukemia.

Anatomy yamagufwa. Igufwa rigizwe n'amagufwa magufi, amagufwa ya spongy, n'amagufwa. Amagufwa magufi agize igice cyinyuma cyamagufwa. Amagufwa ya spongy aboneka cyane kumpera yamagufa kandi arimo umusemburo utukura. Amagufwa yo mu magufa aboneka hagati yamagufwa menshi kandi afite imiyoboro myinshi yamaraso. Hariho ubwoko bubiri bwamagufwa: umutuku numuhondo. Umutuku utukura urimo ingirangingo z'amaraso zishobora guhinduka selile zitukura, selile yera, cyangwa platine. Umuhondo wumuhondo ugizwe ahanini namavuta.

Leukemia irashobora kwanduza selile zitukura, selile yera, na platine.

Mubisanzwe, igufwa ryamagufa ritera ingirangingo zamaraso (selile zidakuze) zihinduka selile yamaraso ikuze mugihe runaka. Ingirabuzimafatizo y'amaraso irashobora guhinduka myeloid stem selile cyangwa lymphoide stem selile. Lymphoide stem selile iba selile yera.

Ingirabuzimafatizo ya myeloid ihinduka bumwe mu bwoko butatu bw'amaraso akuze:

• Uturemangingo twamaraso dutukura dutwara ogisijeni nibindi bintu mubice byose byumubiri.

• Utugingo ngengabuzima twera turwanya indwara n'indwara.

• Amashanyarazi akora amaraso kugirango areke kuva amaraso.

Gukura kw'amaraso. Ingirabuzimafatizo y'amaraso inyura mu ntambwe nyinshi kugirango ihinduke selile itukura, platine, cyangwa selile yera.

Muri AML, selile stem myeloid mubisanzwe ihinduka ubwoko bwamaraso yera adakuze yitwa myeloblasts (cyangwa myeloid blasts). Myeloblasts muri AML ntisanzwe kandi ntabwo iba selile yera yera. Rimwe na rimwe muri AML, ingirabuzimafatizo nyinshi zihinduka selile zitukura zidasanzwe cyangwa platine. Utugingo ngengabuzima twera bidasanzwe, selile zitukura, cyangwa platine nazo bita selile leukemia cyangwa guturika. Ingirabuzimafatizo za Leukemia zirashobora kwiyubaka mu magufa no mu maraso bityo hakaba hataboneka umwanya muto w'uturemangingo tw'amaraso twera, selile zitukura, na platine. Iyo ibi bibaye, kwandura, kubura amaraso, cyangwa kuva amaraso byoroshye birashobora kubaho. Ingirabuzimafatizo ya leukemia irashobora gukwirakwira hanze yamaraso mu bindi bice byumubiri, harimo na sisitemu yo hagati (ubwonko nu mugongo), uruhu, nishinya.

Iyi ncamake ivuga kubyerekeye AML ikuze. Reba incamake ya ikurikira kumakuru yerekeye ubundi bwoko bwa leukemia:

• Ubwana Bukaze Myeloid Leukemia / Ubundi buryo bwo kuvura indwara ya Myeloid

• Umuti wa karande Myelogenous Leukemia

• Abakuze Bavura Lymphoblastique Kuvura Leukemia

• Ubwana bwo kuvura Lymphoblastique Leukemia

• Kuvura indwara ya Lymphocytike idakira

• Umuti wimitsi ya leukemia

Hariho ubwoko butandukanye bwa AML.

Ubwoko bwinshi bwa AML bushingiye kuburyo ingirabuzimafatizo za kanseri zikuze (zateye imbere) mugihe cyo kwisuzumisha nuburyo zitandukanye na selile zisanzwe.

Acute promyelocytic leukemia (APL) ni ubwoko bwa AML bubaho mugihe ibice bigize genes ebyiri bifatanye. Ubusanzwe APL iboneka mubantu bakuze. Ibimenyetso bya APL birashobora kuba birimo kuva amaraso no gukora amaraso.

Kunywa itabi, kuvura imiti ya chimiotherapie, hamwe no guhura nimirase bishobora kugira ingaruka kumuntu mukuru AML.

Ikintu cyose cyongera ibyago byo kwandura byitwa impanuka. Kugira ibintu bishobora guteza ibyago ntibisobanura ko uzarwara kanseri; kutagira ibyago bishobora gusobanura ko utazarwara kanseri. Vugana na muganga wawe niba utekereza ko ushobora guhura n'akaga. Impamvu zishobora gutera ingaruka kuri AML zirimo ibi bikurikira:

• Kuba umugabo.

• Kunywa itabi, cyane cyane nyuma yimyaka 60.

• Kugira ubuvuzi hamwe na chimiotherapie cyangwa imiti ivura imirasire kera.

• Kuba waravuwe mu bwana bukabije lymphoblastique leukemia (BYOSE) kera.

• Guhura nimirasire ituruka kuri bombe atomike cyangwa kuri benzene yimiti.

• Kugira amateka yuburwayi bwamaraso nka myelodysplastic syndrome.

Ibimenyetso nibimenyetso byabakuze AML harimo umuriro, kumva unaniwe, no gukomeretsa byoroshye cyangwa kuva amaraso.

Ibimenyetso hakiri kare nibimenyetso bya AML birashobora kumera nkibitera ibicurane cyangwa izindi ndwara zisanzwe. Menyesha umuganga wawe niba ufite kimwe muri ibi bikurikira:

• Umuriro.

• Kubura umwuka.

• Gukomeretsa byoroshye cyangwa kuva amaraso.

• Petechiae (ibibara binini, bitagaragara munsi yuruhu biterwa no kuva amaraso).

• Intege nke cyangwa kumva unaniwe.

• Kugabanuka ibiro cyangwa kubura ubushake bwo kurya.

Ibizamini bisuzuma amaraso n'amagufa bikoreshwa mugushakisha (gushakisha) no gusuzuma AML ikuze.

Ibizamini hamwe nuburyo bukurikira birashobora gukoreshwa:

• Ikizamini cyumubiri namateka: Ikizamini cyumubiri kugirango ugenzure ibimenyetso rusange byubuzima, harimo no gusuzuma ibimenyetso byindwara, nkibibyimba cyangwa ikindi kintu cyose gisa nkidasanzwe. Hazafatwa kandi amateka yubuzima bwumurwayi nindwara zashize hamwe nubuvuzi.

• Kubara amaraso yuzuye (CBC): Uburyo bwo gukuramo urugero rwamaraso no gusuzuma ibi bikurikira:

• Umubare w'uturemangingo tw'amaraso atukura, selile yera, na platine.

• Ingano ya hemoglobine (proteyine itwara ogisijeni) mu ngirangingo z'amaraso atukura.

• Igice cy'icyitegererezo kigizwe na selile zitukura.

Kubara amaraso yuzuye (CBC). Amaraso akusanywa no kwinjiza inshinge mumitsi no kwemerera amaraso gutembera mumiyoboro. Icyitegererezo cyamaraso cyoherezwa muri laboratoire hanyuma selile zitukura, selile yera, na platine zirabaze. CBC ikoreshwa mugupima, gusuzuma, no gukurikirana ibintu byinshi bitandukanye.

• Amaraso ya periferique: Uburyo bwo gusuzuma urugero rwamaraso kugirango hamenyekane selile ziturika, umubare nubwoko bwingirangingo zamaraso yera, umubare wa platine, hamwe nimpinduka mumiterere ya selile.

• Amagufa ya marrow aspiration na biopsy: Gukuraho igufwa ryamagufa, amaraso, nigice gito cyamagufwa winjiza urushinge rudafite epfo na ruguru cyangwa amabere. Inzobere mu by'indwara ireba amagufwa, amaraso, n'amagufwa munsi ya microscope kugira ngo ishakishe ibimenyetso bya kanseri.

Amagufa ya marrow icyifuzo na biopsy. Nyuma yuko agace gato k'uruhu kamaze kunanirwa, urushinge rw'amagufwa rwinjizwa mu igufwa ry'umurwayi. Ingero z'amaraso, amagufwa, n'amagufwa byavanyweho kugirango bisuzumwe kuri microscope.

• Isesengura rya Cytogenetike: Ikizamini cya laboratoire aho chromosomes ya selile iri mu cyitegererezo cyamaraso cyangwa igufwa ryamagufwa ikabarwa kandi ikagenzurwa niba hari impinduka, nko kuvunika, kubura, gutondekanya, cyangwa chromosomes ziyongera. Impinduka muri chromosomes zimwe zishobora kuba ikimenyetso cya kanseri. Isesengura rya Cytogenetike rikoreshwa mu gufasha gusuzuma kanseri, gutegura gahunda yo kuvura, cyangwa kumenya uburyo ubuvuzi bukora neza. Ibindi bizamini, nka fluorescence muburyo bwa Hybridisation (FISH), birashobora kandi gukorwa kugirango harebwe impinduka zimwe na zimwe muri chromosomes.

• Immunophenotyping: Ikizamini cya laboratoire ikoresha antibodies kugirango hamenyekane kanseri ya kanseri ukurikije ubwoko bwa antigene cyangwa ibimenyetso hejuru ya selile. Iki kizamini gikoreshwa mugufasha gusuzuma ubwoko bwihariye bwa leukemia. Kurugero, ubushakashatsi bwa cytochemie bushobora gupima selile murugero rwa tissue ukoresheje imiti (amarangi) kugirango ushakishe impinduka zimwe murugero. Imiti irashobora gutera ibara muburyo bumwe bwa selile ya leukemia ariko ntabwo mubundi bwoko bwa selile leukemia.

• Isubiramo ryinyandiko - polymerase urunigi rwibisubizo (RT - PCR): Ikizamini cya laboratoire gipimwa ingano yibintu bikomoka ku ngirabuzima fatizo byitwa mRNA bikozwe na gen runaka. Enzyme yitwa reverse transcriptase ikoreshwa muguhindura igice runaka cya RNA mukigice cya ADN gihuye, gishobora kongerwa (cyakozwe mubwinshi) nindi misemburo yitwa ADN polymerase. Kopi ya ADN yongerewe ifasha kumenya niba mRNA yihariye ikorwa na gene. RT-PCR irashobora gukoreshwa mugusuzuma imikorere ya genes zimwe na zimwe zishobora kwerekana ko hari kanseri ya kanseri. Iki kizamini gishobora gukoreshwa mugushakisha impinduka zimwe na zimwe muri gen cyangwa chromosome, zishobora gufasha gusuzuma kanseri. Iki kizamini gikoreshwa mugupima ubwoko bumwe na bumwe bwa AML harimo na leyemia ikaze ya promyelocytic (APL).

Ibintu bimwe bigira ingaruka kubitekerezo (amahirwe yo gukira) hamwe nuburyo bwo kuvura.

Kumenyekanisha (amahirwe yo gukira) hamwe nuburyo bwo kuvura biterwa na:

• Imyaka yumurwayi.

• Ubwoko bwa AML.

• Niba umurwayi yarahawe chimiotherapie kera kugirango avure kanseri itandukanye.

• Niba hari amateka yuburwayi bwamaraso nka syndrome ya myelodysplastic.

• Niba kanseri yarakwirakwiriye muri sisitemu yo hagati.

• Niba kanseri yaravuwe mbere cyangwa yagarutse (garuka).

Ni ngombwa ko leukemia ikaze ivurwa ako kanya.

Ibyiciro by'abakuze Acute Myeloid Leukemia

INGINGO Z'INGENZI

• Bimaze gupimwa abantu bakuru acute myeloid leukemia (AML), hakorwa ibizamini kugirango hamenyekane niba kanseri yarakwirakwiriye mu bindi bice by'umubiri.

• Nta sisitemu isanzwe yo kubika AML ikuze.

Bimaze gupimwa abantu bakuru acute myeloid leukemia (AML), hakorwa ibizamini kugirango hamenyekane niba kanseri yarakwirakwiriye mu bindi bice by'umubiri.

Ingano cyangwa ikwirakwizwa rya kanseri mubisanzwe bisobanurwa nkibyiciro. Mubantu bakuze acute myeloid leukemia (AML), subtype ya AML no kumenya niba leukemia yarakwirakwiriye hanze yamaraso hamwe namagufwa yamagufa bikoreshwa aho gukoresha stade kugirango bategure kuvura. Ibizamini hamwe nuburyo bukurikira birashobora gukoreshwa kugirango hamenyekane niba leukemia yarakwirakwiriye:

• Gutobora Lumbar: Uburyo bukoreshwa mugukusanya icyitegererezo cyamazi yo mu bwonko (CSF) kuva kumugongo. Ibi bikorwa mugushira urushinge hagati yamagufa abiri murugongo no muri CSF ikikije uruti rwumugongo no gukuramo icyitegererezo cyamazi. Icyitegererezo cya CSF gisuzumwa munsi ya microscope kugirango ibimenyetso byerekana ko selile ya leukemia yakwirakwiriye mu bwonko no mu ruti rw'umugongo. Ubu buryo bwitwa LP cyangwa igikanda.

Gutobora. Umurwayi aryamye mumwanya uhetamye kumeza. Nyuma yumwanya muto kumugongo wo hasi ucecetse, urushinge rwumugongo (urushinge rurerure, ruto) rwinjizwa mubice byo hepfo yinkingi yumugongo kugirango rukureho ubwonko bwubwonko (CSF, bwerekanwe mubururu). Amazi arashobora koherezwa muri laboratoire kugirango isuzumwe.

• CT scan (CAT scan): Uburyo bukora urukurikirane rwamashusho arambuye yinda, yakuwe muburyo butandukanye. Amashusho yakozwe na mudasobwa ihujwe na mashini ya x-ray. Irangi rishobora guterwa mumitsi cyangwa kumirwa kugirango bifashe ingingo cyangwa ingirangingo kugaragara neza. Ubu buryo nabwo bwitwa computing tomografiya, tomografiya ya mudasobwa, cyangwa mudasobwa ya axial tomografiya.

Nta sisitemu isanzwe yo kubika AML ikuze.

Indwara isobanurwa ko itavuwe, mu gukira, cyangwa kugaruka.

AML ikuze itavuwe

Muri AML ikuze itavuwe, indwara irasuzumwa vuba. Ntabwo yigeze ivurwa usibye kugabanya ibimenyetso nibimenyetso nkumuriro, kuva amaraso, cyangwa ububabare, kandi ibi bikurikira nukuri:

• Umubare wuzuye wamaraso ntusanzwe.

• Nibura 20% by'utugingo ngengabuzima two mu magufa ni uguturika (selile leukemia).

• Hano hari ibimenyetso cyangwa ibimenyetso bya leukemia.

Abakuze AML mubisubizo

Mu bantu bakuze AML mu gukira, indwara yaravuwe kandi ibikurikira ni ukuri:

• Kubara amaraso byuzuye nibisanzwe.

• Hafi ya 5% yingirabuzimafatizo ziri mu magufa ni uguturika (selile leukemia).

• Nta bimenyetso cyangwa ibimenyetso bya leukemia mu bwonko no mu ruti rw'umugongo cyangwa ahandi mu mubiri.

Isubiramo Abakuze AML

AML isubiramo ni kanseri yagarutse (garuka) imaze kuvurwa. AML irashobora kugaruka mumaraso cyangwa mumagufa.

Incamake yo kuvura

INGINGO Z'INGENZI

• Hariho uburyo butandukanye bwo kuvura abarwayi bafite acute myeloid leukemia.
• Ubuvuzi bwa AML bukuze busanzwe bufite ibyiciro 2.
• Ubwoko bune bwo kuvura busanzwe bukoreshwa:

• Chimoterapi

• Imiti ivura imirasire

• Chimoterapi hamwe no guhinduranya ingirangingo

• Ubundi buryo bwo kuvura ibiyobyabwenge

• Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.

• Ubuvuzi bugamije

• Umuti kubantu bakuze acute myeloid leukemia irashobora gutera ingaruka.

• Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.

• Abarwayi barashobora kwipimisha kwa muganga mbere, mugihe, cyangwa nyuma yo gutangira kuvura kanseri.

• Ibizamini byo gukurikirana birashobora gukenerwa.

Hariho uburyo butandukanye bwo kuvura abarwayi bafite acute myeloid leukemia.

Ubwoko butandukanye bwo kuvura burahari kubarwayi barwaye acute myeloid leukemia (AML). Bumwe mu buryo busanzwe (ubuvuzi bukoreshwa ubu), kandi bumwe burimo kugeragezwa mubigeragezo byamavuriro. Ikigeragezo kivura ni ubushakashatsi bwakozwe bugamije gufasha kunoza imiti igezweho cyangwa kubona amakuru ku buvuzi bushya ku barwayi ba kanseri. Iyo ibizamini byo kwa muganga byerekana ko ubuvuzi bushya buruta ubuvuzi busanzwe, ubuvuzi bushya bushobora kuba ubuvuzi busanzwe. Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga. Ibigeragezo bimwe na bimwe bivura abarwayi batatangiye kwivuza.

Ubuvuzi bwa AML bukuze busanzwe bufite ibyiciro 2.

Ibyiciro 2 byo kuvura byabakuze AML ni:

• Ubuvuzi bwa Remuction induction: Iki nicyiciro cyambere cyo kuvura. Intego nukwica selile ya leukemia mumaraso no mumagufa. Ibi bishyira leukemia mubisubizo.

• Ubuvuzi bwa post-remission: Iki nicyiciro cya kabiri cyo kuvura. Iratangira nyuma ya leukemia iri mubisubizo. Intego yo kuvura nyuma yo kuvura ni ukwica selile zose zisigaye zishobora kuba zidakora ariko zishobora gutangira kwiyongera no gutera kwisubiraho. Iki cyiciro nanone cyitwa remission gukomeza kuvura.

Ubwoko bune bwo kuvura busanzwe bukoreshwa:

Chimoterapi

Chimiotherapie ni umuti wa kanseri ukoresha ibiyobyabwenge kugirango uhagarike imikurire ya kanseri, haba mu kwica selile cyangwa kubabuza gutandukana. Iyo chimiotherapie ifashwe numunwa cyangwa igaterwa mumitsi cyangwa imitsi, imiti yinjira mumaraso kandi irashobora kugera kanseri ya kanseri mumubiri (chimiotherapie sisitemu). Iyo chimiotherapie ishyizwe mumazi ya cerebrospinal fluid (intrathecal chimiotherapie), urugingo, cyangwa umwobo wumubiri nkinda, imiti yibasira kanseri ya kanseri muri utwo turere (chimiotherapie yo mukarere). Imiti ya chimiotherapie irashobora gukoreshwa mu kuvura AML ikuze yakwirakwiriye mu bwonko no mu ruti rw'umugongo. Imiti ya chimiotherapie ni imiti ikoresheje imiti irenze imwe ya anticancer.

Uburyo chimiotherapie itangwa biterwa na subtype ya AML ivurwa kandi niba selile leukemia yakwirakwiriye mubwonko no mugongo.

Imiti ya chimiotherapie. Imiti igabanya ubukana yatewe mu mwanya wa intrathecal, niwo mwanya ufite amazi yo mu bwonko (CSF, yerekanwe mu bururu). Hariho inzira ebyiri zitandukanye zo gukora ibi. Bumwe mu buryo, bwerekanwa mu gice cyo hejuru cy’ishusho, ni ugutera imiti mu kigega cya Ommaya (ikintu kimeze nk'ikibumbano gishyirwa munsi y’umutwe mu gihe cyo kubagwa; gifata imiti uko inyura mu muyoboro muto mu bwonko ). Ubundi buryo, bwerekanwe mugice cyo hasi cyigishushanyo, ni ugutera inshinge muri CSF mugice cyo hepfo yinkingi yumugongo, nyuma yumwanya muto kumugongo wo hasi ubuze.

Reba ibiyobyabwenge byemewe kuri Acute Myeloid Leukemia kubindi bisobanuro.

Imiti ivura imirasire

Imishwarara ivura ni imiti ikoresha kanseri ikoresha ingufu nyinshi za x-imirasire cyangwa ubundi bwoko bwimirasire yica kanseri cyangwa ikabuza gukura. Hariho ubwoko bubiri bwo kuvura imirasire:

• Imiti ivura hanze ikoresha imashini hanze yumubiri kugirango yohereze imirasire kuri kanseri.

• Imiti ivura imbere ikoresha ibintu bifata radiyo bifunze inshinge, imbuto, insinga, cyangwa catheteri bishyirwa muri kanseri cyangwa hafi yayo.

Uburyo imiti ivura imirasire itangwa biterwa n'ubwoko bwa kanseri ivurwa no kumenya niba selile ya leukemia yakwirakwiriye mu bwonko no mu ruti rw'umugongo. Imiti yo hanze ivura ikoreshwa mu kuvura AML ikuze.

Chimoterapi hamwe no guhinduranya ingirangingo

Chimiotherapie itangwa kugirango yice selile. Ingirabuzimafatizo nzima, harimo na selile zikora amaraso, nazo zirasenywa no kuvura kanseri. Gutera ingirabuzimafatizo ni uburyo bwo gusimbuza ingirabuzimafatizo. Ingirabuzimafatizo (selile zidakuze) zivanwa mumaraso cyangwa igufwa ryumurwayi cyangwa umuterankunga hanyuma bikonjeshwa bikabikwa. Nyuma yuko umurwayi arangije chimiotherapie, selile stem yabitswe irashonga hanyuma igasubizwa umurwayi binyuze muri infusion. Izi ngirabuzimafatizo zongeye gukoreshwa zikura (kandi zigarura) ingirangingo z'amaraso z'umubiri.

Gutera ingirabuzimafatizo. (Intambwe ya 1): Amaraso yakuwe mumitsi mumaboko yumuterankunga. Umurwayi cyangwa undi muntu ashobora kuba umuterankunga. Amaraso atembera mumashini ikuraho ingirabuzimafatizo. Noneho amaraso asubizwa abaterankunga binyuze mumitsi mumaboko yandi. (Intambwe ya 2): Umurwayi yakira chimiotherapie kugirango yice selile zikora amaraso. Umurwayi arashobora guhabwa imiti ivura imirasire (iterekanwa). (Intambwe ya 3): Umurwayi yakira ingirabuzimafatizo binyuze muri catheter yashyizwe mu maraso mu gituza.

Ubundi buryo bwo kuvura ibiyobyabwenge

Arsenic trioxide na aside-retinoic aside yose (ATRA) ni imiti igabanya ubukana yica selile ya leukemia, ikabuza selile leukemia kugabana, cyangwa ifasha selile ya leukemia gukura mumasemburo yera. Iyi miti ikoreshwa mukuvura ubwoko bwa AML bwitwa acute promyelocytic leukemia.

Reba ibiyobyabwenge byemewe kuri Acute Myeloid Leukemia kubindi bisobanuro.

Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.

Iki gice cyincamake gisobanura imiti irimo kwigwa mubigeragezo byamavuriro. Ntishobora kuvuga ubuvuzi bushya burimo kwigwa. Amakuru yerekeye ibizamini byamavuriro araboneka kurubuga rwa NCI.

Ubuvuzi bugamije

Ubuvuzi bugamije ni uburyo bwo kuvura bukoresha ibiyobyabwenge cyangwa ibindi bintu kugirango umenye kandi utere kanseri yihariye ya kanseri utangiza ingirabuzimafatizo zisanzwe. Ubuvuzi bwa antibody ya Monoclonal ni bumwe mu buryo bwo kuvura bugamije kwigwa mu kuvura AML ikuze.

Ubuvuzi bwa Monoclonal antibody nubuvuzi bwa kanseri bukoresha antibodies zakozwe muri laboratoire ziva mubwoko bumwe bwimikorere yumubiri. Iyi antibodies irashobora kumenya ibintu biri muri kanseri ya kanseri cyangwa ibintu bisanzwe bishobora gufasha kanseri gukura. Antibodiyite ifata ibintu kandi ikica selile ya kanseri, ikabuza gukura kwayo, cyangwa ikabuza gukwirakwira. Antibodiyite za Monoclonal zitangwa no gushiramo. Bashobora gukoreshwa bonyine cyangwa gutwara ibiyobyabwenge, uburozi, cyangwa ibikoresho bya radio bikoresha kanseri ya kanseri.

Umuti kubantu bakuze acute myeloid leukemia irashobora gutera ingaruka.

Kumakuru yingaruka ziterwa no kuvura kanseri, reba urupapuro rwuruhande rwacu.

Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.

Ku barwayi bamwe, kwitabira ikizamini cyamavuriro birashobora kuba uburyo bwiza bwo kuvura. Ibigeragezo bivura biri mubikorwa byubushakashatsi bwa kanseri. Igeragezwa rya Clinical rikorwa kugirango hamenyekane niba imiti mishya ya kanseri itekanye kandi ifite akamaro cyangwa nziza kuruta ubuvuzi busanzwe.

Benshi mubuvuzi busanzwe bwa kanseri bushingiye kubigeragezo byambere byubuvuzi. Abarwayi bitabiriye kwipimisha barashobora kuvurwa bisanzwe cyangwa kuba mubambere bahawe imiti mishya.

Abarwayi bitabira ibizamini byo kwa muganga nabo bafasha kunoza uburyo kanseri izavurwa mugihe kizaza. Nubwo ibigeragezo bivura bitaganisha ku buvuzi bushya, akenshi basubiza ibibazo byingenzi kandi bigafasha gutera imbere ubushakashatsi.

Abarwayi barashobora kwipimisha kwa muganga mbere, mugihe, cyangwa nyuma yo gutangira kuvura kanseri.

Igeragezwa rimwe na rimwe ririmo abarwayi bataravurwa. Ibindi bigeragezo bipima abarwayi bafite kanseri itameze neza. Hariho kandi ibizamini byo kwa muganga bipima uburyo bushya bwo guhagarika kanseri kongera kugaruka (kugaruka) cyangwa kugabanya ingaruka zo kuvura kanseri.

Igeragezwa rya Clinical ririmo kubera mu bice byinshi by'igihugu. Amakuru yerekeye ibizamini byamavuriro ashyigikiwe na NCI urashobora kubisanga kurubuga rwa NCI. Ibizamini bya Clinical bishyigikiwe nandi mashyirahamwe murashobora kubisanga kurubuga rwa ClinicalTrials.gov.

Ibizamini byo gukurikirana birashobora gukenerwa.

Bimwe mubizamini byakozwe mugupima kanseri cyangwa kumenya icyiciro cya kanseri birashobora gusubirwamo. Ibizamini bimwe bizasubirwamo kugirango harebwe uburyo ubuvuzi bukora neza. Ibyemezo bijyanye no gukomeza, guhindura, cyangwa guhagarika ubuvuzi birashobora gushingira kubisubizo byibi bizamini.

Bimwe mubizamini bizakomeza gukorwa buri gihe nyuma yubuvuzi burangiye. Ibisubizo by'ibi bizamini birashobora kwerekana niba ubuzima bwawe bwarahindutse cyangwa niba kanseri yarongeye (garuka). Ibi bizamini rimwe na rimwe byitwa gukurikirana-ibizamini cyangwa kugenzura.

Amahitamo yo kuvura kubantu bakuze Myeloid Leukemia

Muri iki gice

• Abakuze batavuwe Acute Myeloid Leukemia

• Abakuze Acute Myeloid Leukemia muri Remission

• Isubiramo Abakuze Acute Myeloid Leukemia

Kumakuru yerekeye imiti yavuzwe hepfo, reba igice cyo kuvura.

Abakuze batavuwe Acute Myeloid Leukemia

Ubuvuzi busanzwe bwabantu bakuru batavuwe acute myeloid leukemia (AML) mugihe cyicyiciro cyo kwinjiza imiti biterwa nubwoko bwa AML kandi bushobora kubamo ibi bikurikira:

• Ubuvuzi bwa chimiotherapie.

• Imiti ikabije ya chimiotherapie.

• Imiti mike ya chimiotherapie.

• Imiti ya chimiotherapie.

• All-trans retinoic aside (ATRA) hiyongereyeho arsenic trioxide yo kuvura indwara ya leukemia ikaze (APL).

• ATRA hiyongereyeho chimiotherapie ikurikirwa na arsenic trioxide yo kuvura APL.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Abakuze Acute Myeloid Leukemia muri Remission

Kuvura AML akuze mugihe cyo gukuraho biterwa na subtype ya AML kandi irashobora kubamo ibi bikurikira:

• Ubuvuzi bwa chimiotherapie.

• Imiti myinshi ya chimiotherapie, hamwe cyangwa idafite imiti ivura imirasire, hamwe no guhinduranya ingirabuzimafatizo ukoresheje ingirangingo z'umurwayi.

• Imiti myinshi ya chimiotherapie hamwe no guhinduranya ingirabuzimafatizo ukoresheje ingirabuzimafatizo.

• Ikigeragezo cyamavuriro ya arsenic trioxide.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Isubiramo Abakuze Acute Myeloid Leukemia

Nta buryo busanzwe bwo kuvura AML ikuze. Ubuvuzi buterwa n'ubwoko bwa AML kandi bushobora kubamo ibi bikurikira:

• Ubuvuzi bwa chimiotherapie.

• Ubuvuzi bugamije hamwe na antibodiyite za monoclonal.

• Gutera ingirabuzimafatizo ukoresheje ingirangingo z'umurwayi cyangwa ingirabuzimafatizo.

• Arsenic trioxide ivura.

• Igeragezwa rya clinique yubuvuzi bwa arsenic trioxide ikurikirwa no guterwa ingirangingo.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Kumenya Byinshi Kubantu Bakuze Myeloid Kanseri ya Leukemia

Ushaka amakuru menshi yikigo cyigihugu cya kanseri kubyerekeye abakuze acute myeloid leukemia, reba ibi bikurikira:

• Urupapuro rwa Leukemia

• Ibiyobyabwenge Byemewe Kurwara Myeloid Leukemia

• Gutera Amaraso Yimitsi Yimitsi

• Intego zo kuvura Kanseri

Kumakuru rusange ya kanseri nibindi bikoresho biva mu kigo cyigihugu cya kanseri, reba ibi bikurikira:

• Ibyerekeye Kanseri

• Gutegura

• Chimiotherapie nawe: Inkunga kubantu barwaye Kanseri

• Ubuvuzi bwimirasire nawe: Inkunga kubantu barwaye Kanseri

• Guhangana na Kanseri

• Ibibazo byo Kubaza Muganga wawe kuri Kanseri

• Abacitse ku icumu n'abarezi