Ubwoko / langerhans / umurwayi / langerhans-kuvura-pdq

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Langerhans Cell Histiocytose Yivura (®) - Indwara yabarwayi

Amakuru Rusange Yerekeye Langerhans Cell Histiocytose (LCH)

INGINGO Z'INGENZI

  • Langerhans selile histiocytose ni ubwoko bwa kanseri ishobora kwangiza ingirangingo cyangwa igatera ibikomere ahantu hamwe cyangwa henshi mumubiri.
  • Amateka yumuryango wa kanseri cyangwa kugira umubyeyi wahuye nimiti imwe n'imwe bishobora kongera ibyago bya LCH.
  • Ibimenyetso nibimenyetso bya LCH biterwa nigihe biri mumubiri.
  • Uruhu n'imisumari
  • Umunwa
  • Amagufwa
  • Indirimbo ya Lymph na thymus
  • Sisitemu ya Endocrine
  • Ijisho
  • Sisitemu yo hagati (CNS)
  • Umwijima n'impyiko
  • Ibihaha
  • Amagufwa
  • Ibizamini bisuzuma ingingo na sisitemu yumubiri aho LCH ishobora kugaragara ikoreshwa mugupima LCH.
  • Ibintu bimwe bigira ingaruka kubitekerezo (amahirwe yo gukira) hamwe nuburyo bwo kuvura.

Langerhans selile histiocytose ni ubwoko bwa kanseri ishobora kwangiza ingirangingo cyangwa igatera ibikomere ahantu hamwe cyangwa henshi mumubiri.

Langerhans selile histiocytose (LCH) ni kanseri idasanzwe itangirira muri selile LCH. LCH selile ni ubwoko bwa selile dendritic irwanya kwandura. Rimwe na rimwe hariho ihinduka (impinduka) muri selile LCH uko zikora. Harimo ihinduka ryimiterere ya BRAF, MAP2K1, RAS na ARAF. Izi mpinduka zirashobora gutuma LCH selile ikura kandi ikagwira vuba. Ibi bitera selile LCH kwiyubaka mubice bimwe byumubiri, aho bishobora kwangiza ingirangingo cyangwa gukora ibikomere.

LCH ntabwo ari indwara ya selile ya Langerhans isanzwe iboneka muruhu.

LCH irashobora kubaho mumyaka iyo ari yo yose, ariko ikunze kugaragara mubana bato. Kuvura LCH mubana bitandukanye no kuvura LCH kubantu bakuru. Ubuvuzi bwa LCH mubana no kuvura LCH mubantu bakuru bisobanurwa mubice bitandukanye byiyi ncamake.

Amateka yumuryango wa kanseri cyangwa kugira umubyeyi wahuye nimiti imwe n'imwe bishobora kongera ibyago bya LCH.

Ikintu cyose cyongera ibyago byo kwandura byitwa impanuka. Kugira ibintu bishobora guteza ibyago ntibisobanura ko uzarwara kanseri; kutagira ibyago bishobora gusobanura ko utazarwara kanseri. Vugana na muganga wawe niba utekereza ko ushobora guhura n'akaga.

Impamvu zishobora gutera LCH zirimo ibi bikurikira:

  • Kugira umubyeyi wasangaga imiti imwe n'imwe.
  • Kugira umubyeyi wahuye nicyuma, granite, cyangwa umukungugu wibiti kumurimo.
  • Amateka yumuryango wa kanseri, harimo na LCH.
  • Kugira amateka yihariye cyangwa amateka yumuryango yindwara ya tiroyide.
  • Kugira kwandura nkumwana ukivuka.
  • Kunywa itabi, cyane cyane mu rubyiruko rukuze.
  • Kuba Hispanic.
  • Kudakingirwa nkumwana.

Ibimenyetso nibimenyetso bya LCH biterwa nigihe biri mumubiri.

Ibi nibindi bimenyetso nibimenyetso bishobora guterwa na LCH cyangwa nibindi bihe. Menyesha umuganga wawe niba wowe cyangwa umwana wawe ufite kimwe muri ibi bikurikira:

Uruhu n'imisumari

LCH mu mpinja zishobora kugira ingaruka ku ruhu gusa. Rimwe na rimwe, LCH yonyine y'uruhu irashobora kuba mibi mugihe cyibyumweru cyangwa ukwezi hanyuma igahinduka uburyo bwitwa ibyago byinshi-byinshi LCH.

Mu mpinja, ibimenyetso cyangwa ibimenyetso bya LCH bigira ingaruka ku ruhu bishobora kuba birimo:

  • Kumenagura igihanga gishobora kumera nk "ingofero yumutwe".
  • Kuzunguruka mu bice by'umubiri, nk'inkokora y'imbere cyangwa perineum.
  • Kuzamura uruhu, umukara cyangwa umutuku wijimye ahantu hose kumubiri.

Mu bana no mu bantu bakuru, ibimenyetso cyangwa ibimenyetso bya LCH bigira ingaruka ku ruhu no ku nzara bishobora kubamo:

  • Kumenagura igihanga gishobora kumera nka dandruff.
  • Kuzamurwa, umutuku cyangwa umutuku, guhubuka mu gice cyigituba, inda, umugongo, cyangwa igituza, bishobora kuba bikabije cyangwa bibabaza.
  • Ibibyimba cyangwa ibisebe kumutwe.
  • Ibisebe inyuma y'amatwi, munsi y'amabere, cyangwa mu kibero.
  • Urutoki rugwa cyangwa rufite ibara risize ibara ryambukiranya umusumari.

Umunwa

Ibimenyetso cyangwa ibimenyetso bya LCH bigira ingaruka kumunwa bishobora kubamo:

  • Amenyo yabyimbye.
  • Ibisebe hejuru yinzu, imbere mumatama, cyangwa kururimi cyangwa iminwa.

Amenyo ahinduka cyangwa ataguye.

Amagufwa

Ibimenyetso cyangwa ibimenyetso bya LCH bigira ingaruka kumagufa bishobora kuba birimo:

  • Kubyimba cyangwa ibibyimba hejuru yamagufa, nka gihanga, urwasaya, imbavu, pelvis, umugongo, igufwa ryibibero, igufwa ryamaboko yo hejuru, inkokora, ijisho, cyangwa amagufwa azenguruka ugutwi.
  • Kubabara ahari kubyimba cyangwa kubyimba hejuru yamagufa.

Abana bafite ibikomere bya LCH mumagufwa akikije amatwi cyangwa amaso bafite ibyago byinshi byo kurwara diyabete insipidus nizindi ndwara zifata imitsi yo hagati.

Indirimbo ya Lymph na thymus

Ibimenyetso cyangwa ibimenyetso bya LCH bigira ingaruka kuri lymph node cyangwa thymus bishobora kubamo:

  • Indwara ya lymph node.
  • Guhumeka.
  • Indwara ya vena cava syndrome. Ibi birashobora gutera inkorora, guhumeka neza, no kubyimba mumaso, ijosi, namaboko yo hejuru.

Sisitemu ya Endocrine

Ibimenyetso cyangwa ibimenyetso bya LCH yibasira glande ya pitoito irashobora kubamo:

  • Indwara ya Diyabete. Ibi birashobora gutera inyota ikomeye no kwihagarika kenshi.
  • Gukura buhoro.
  • Ubugimbi cyangwa kare.
  • Kuba ufite umubyibuho ukabije.

Ibimenyetso cyangwa ibimenyetso bya LCH yibasira tiroyide irashobora kubamo:

  • Indwara ya tiroyide yabyimbye.
  • Indwara ya Hypothyroidism. Ibi birashobora gutera umunaniro, kubura imbaraga, kumva ubukonje, impatwe, uruhu rwumye, umusatsi unanutse, ibibazo byo kwibuka, ibibazo byo gutumbira, no kwiheba. Ku mpinja, ibi birashobora kandi gutera kubura ubushake bwo kurya no kuniga ibiryo. Mu bana n'ingimbi, ibi birashobora kandi gutera ibibazo byimyitwarire, kwiyongera ibiro, gukura gahoro, no gutinda.
  • Guhumeka.

Ijisho

Ibimenyetso cyangwa ibimenyetso bya LCH bigira ingaruka kumaso bishobora kubamo:

  • Ibibazo by'icyerekezo.

Sisitemu yo hagati (CNS)

Ibimenyetso cyangwa ibimenyetso bya LCH bigira ingaruka kuri CNS (ubwonko nu mugongo) bishobora kubamo:

  • Gutakaza uburimbane, kugenda umubiri udahujwe, hamwe ningorane zo kugenda.
  • Kuvuga nabi.
  • Kubona ikibazo.
  • Kubabara umutwe.
  • Guhindura imyitwarire cyangwa imiterere.
  • Ibibazo byo kwibuka.

Ibi bimenyetso nibimenyetso bishobora guterwa no gukomeretsa muri CNS cyangwa na syndrome ya CNS neurodegenerative.

Umwijima n'impyiko

Ibimenyetso cyangwa ibimenyetso bya LCH yibasira umwijima cyangwa ururenda bishobora kuba birimo:

  • Kubyimba munda biterwa no kwiyongera k'amazi adasanzwe.
  • Guhumeka.
  • Umuhondo w'uruhu n'umweru w'amaso.
  • Gucura.
  • Gukomeretsa byoroshye cyangwa kuva amaraso.
  • Kumva unaniwe cyane.

Ibihaha

Ibimenyetso cyangwa ibimenyetso bya LCH yibasira ibihaha bishobora kubamo:

  • Ibihaha byaguye. Iyi miterere irashobora gutera ububabare bwo mu gatuza cyangwa gukomera, guhumeka neza, kumva unaniwe, hamwe nubururu bwijimye kuruhu.
  • Guhumeka neza, cyane cyane mubantu bakuru banywa itabi.
  • Inkorora yumye.
  • Kubabara mu gatuza.

Amagufwa

Ibimenyetso cyangwa ibimenyetso bya LCH bigira ingaruka kumitsi yamagufa bishobora kubamo:

  • Gukomeretsa byoroshye cyangwa kuva amaraso.
  • Umuriro.
  • Indwara kenshi.

Ibizamini bisuzuma ingingo na sisitemu yumubiri aho LCH ishobora kugaragara ikoreshwa mugupima LCH.

Ibizamini nuburyo bukurikira birashobora gukoreshwa mugushakisha (gushakisha) no gusuzuma LCH cyangwa ibihe byatewe na LCH:

  • Ikizamini cyumubiri namateka yubuzima: Ikizamini cyumubiri kugirango ugenzure ibimenyetso rusange byubuzima, harimo no gusuzuma ibimenyetso byindwara, nkibibyimba cyangwa ikindi kintu cyose gisa nkidasanzwe. Hazafatwa kandi amateka yubuzima bwumurwayi nindwara zashize hamwe nubuvuzi.
  • Ikizamini cya Neurologiya: Urukurikirane rwibibazo n'ibizamini byo gusuzuma ubwonko, uruti rw'umugongo, n'imikorere y'imitsi. Ikizamini kigenzura imiterere yumuntu, guhuza, nubushobozi bwo kugenda bisanzwe, nuburyo imitsi, ibyumviro, na refleks ikora. Ibi birashobora kandi kwitwa ikizamini cya neuro cyangwa ikizamini cya neurologic.
  • Umubare wuzuye wamaraso (CBC) ufite itandukaniro: Uburyo bwo gukuramo urugero rwamaraso no gusuzuma ibi bikurikira:
  • Ingano ya hemoglobine (proteyine itwara ogisijeni) mu ngirangingo z'amaraso atukura.
  • Igice cyicyitegererezo cyamaraso kigizwe ningirabuzimafatizo zitukura.
  • Umubare nubwoko bwingirangingo zamaraso yera.
  • Umubare w'uturemangingo tw'amaraso atukura na platine.
  • Ubushakashatsi bwa chimie yamaraso: Uburyo bwo gusuzuma urugero rwamaraso kugirango bapime ingano yibintu bimwe na bimwe bisohoka mumubiri ningingo hamwe nuduce twumubiri. Umubare udasanzwe (uri hejuru cyangwa uri munsi yubusanzwe) ibintu bishobora kuba ikimenyetso cyindwara.
  • Ikizamini cyimikorere yumwijima : Ikizamini cyamaraso yo gupima urugero rwamaraso yibintu bimwe na bimwe birekurwa numwijima. Urwego rwo hejuru cyangwa ruto rw'ibi bintu rushobora kuba ikimenyetso cyindwara mu mwijima.
  • Kwipimisha gene ya BRAF: Ikizamini cya laboratoire isuzumwa icyitegererezo cyamaraso cyangwa tissue kugirango habeho impinduka zimwe na zimwe muri gen BRAF.
  • Urinalysis: Ikizamini cyo gusuzuma ibara ry'inkari n'ibiyirimo, nk'isukari, proteyine, selile zitukura, na selile yera.
  • Ikizamini cyo kubura amazi: Ikizamini cyo gusuzuma umubare winkari zakozwe nimba ziba zegeranijwe mugihe hatanzwe amazi make cyangwa ntayo. Iki kizamini gikoreshwa mugupima diyabete insipidus, ishobora guterwa na LCH.
  • Amagufa ya marrow aspiration na biopsy: Gukuraho igufwa ryamagufwa nigice gito cyamagufwa winjiza urushinge rufunitse muri hipbone. Inzobere mu by'indwara ireba igufwa n'amagufwa munsi ya microscope kugirango ishakishe ibimenyetso bya LCH.
Amagufa ya marrow icyifuzo na biopsy. Nyuma yuko agace gato k'uruhu kamaze kunanirwa, urushinge rw'amagufwa rwinjizwa mu igufwa ry'umurwayi. Ingero z'amaraso, amagufwa, n'amagufwa byavanyweho kugirango bisuzumwe kuri microscope.

Ibizamini bikurikira birashobora gukorwa kuri tissue yakuweho:

  • Immunohistochemie: Ikizamini cya laboratoire ikoresha antibodies kugirango igenzure antigene zimwe na zimwe (marikeri) mu cyitegererezo cyumubiri wumurwayi. Antibodies zisanzwe zifitanye isano na enzyme cyangwa irangi rya fluorescent. Antibodies zimaze guhuza antigen yihariye murugero rwa tissue, enzyme cyangwa irangi irakora, hanyuma antigen irashobora kuboneka munsi ya microscope. Ubu bwoko bwikizamini bukoreshwa mugufasha gusuzuma kanseri no gufasha kubwira ubwoko bumwe bwa kanseri buva mubundi bwoko bwa kanseri.
  • Flow cytometry: Ikizamini cya laboratoire gipima umubare w'utugingo ngengabuzima, ijanisha ry'utugingo ngengabuzima turi mu cyitegererezo, hamwe n'ibiranga ingirabuzimafatizo, nk'ubunini, imiterere, hamwe n'ibimenyetso by'ibibyimba (cyangwa ibindi) kuri Ubuso. Ingirabuzimafatizo ziva mu cyitegererezo cy'amaraso y'umurwayi, igufwa ry'amagufa, cyangwa izindi ngingo zandujwe irangi rya fluorescent, zishyirwa mu mazi, hanyuma zikanyura rimwe na rimwe binyuze mu rumuri. Ibisubizo by'ibizamini bishingiye ku kuntu ingirabuzimafatizo zandujwe irangi rya fluorescent zifata urumuri.
  • Gusikana amagufa: Uburyo bwo kugenzura niba hari amagufwa agabanya vuba mumagufwa. Umubare muto cyane wibikoresho bya radio bitera mumitsi kandi bikanyura mumaraso. Ibikoresho bya radiyoyakusanyiriza mu magufa hamwe na kanseri kandi bigaragazwa na scaneri.
Gusikana amagufwa. Umubare muto wibikoresho bya radio bitera mumitsi yumwana kandi bikanyura mumaraso. Ibikoresho bya radiyo bikusanya mumagufwa. Mugihe umwana aryamye kumeza anyerera munsi ya scaneri, hamenyekana ibikoresho bya radio bikora amashusho bigakorerwa kuri ecran ya mudasobwa.
  • X-ray: X-ray yingingo namagufa imbere mumubiri. X-ray ni ubwoko bwingufu zishobora kunyura mumubiri no kuri firime, bigakora ishusho yibice byumubiri. Rimwe na rimwe, ubushakashatsi bwakozwe. Ubu ni uburyo bwo x-ray amagufwa yose yo mumubiri.
  • CT scan (CAT scan): Uburyo bukora urukurikirane rwamashusho arambuye yibice byimbere mumubiri, byafashwe muburyo butandukanye. Amashusho yakozwe na mudasobwa ihujwe na mashini ya x-ray. Irangi rishobora guterwa mumitsi cyangwa kumirwa kugirango bifashe ingingo cyangwa ingirangingo kugaragara neza. Ubu buryo nabwo bwitwa computing tomografiya, tomografiya ya mudasobwa, cyangwa mudasobwa ya axial tomografiya.
Kubara tomografiya (CT) scan yinda. Umurwayi aryamye kumeza anyerera mumashini ya CT, ifata amashusho ya x-ray yimbere yumubiri.
  • MRI . Ikintu cyitwa gadolinium gishobora guterwa mumitsi. Gadolinium ikusanyiriza hafi ya selile LCH kugirango igaragare neza ku ishusho. Ubu buryo bwitwa kandi magnetic magnetic resonance imaging (NMRI).
Magnetic resonance imaging (MRI) yinda. Umwana aryamye kumeza anyerera muri scaneri ya MRI, ifata amashusho imbere yumubiri. Urupapuro ku nda yumwana rufasha gukora amashusho neza.
  • PET scan (positron emission tomografi scan): Uburyo bwo kubona selile yibibyimba mumubiri. Umubare muto wa glucose ikora radio (isukari) yatewe mumitsi. PET scaneri izenguruka umubiri kandi ikora ishusho yerekana aho glucose ikoreshwa mumubiri. Tumor selile yerekana neza mwishusho kuko irakora cyane kandi igafata glucose nyinshi kuruta selile zisanzwe.
Positron yoherejwe na tomografiya (PET) scan. Umwana aryamye kumeza anyerera muri PET scaneri. Kuruhuka umutwe hamwe nigitambara cyera bifasha umwana kuryama. Umubare muto wa glucose ikora radio (isukari) yatewe mumitsi yumwana, hanyuma scaneri ikora ishusho yerekana aho glucose ikoreshwa mumubiri. Ingirabuzimafatizo za kanseri zigaragara neza ku ishusho kuko zifata glucose nyinshi kuruta selile zisanzwe.
  • Ikizamini cya Ultrasound: Uburyo bukoreshwa mu majwi menshi y’amajwi (ultrasound) asohoka mu ngingo cyangwa mu ngingo imbere hanyuma agasubiramo. Ijwi ryerekana ishusho yumubiri wumubiri witwa sonogram. Ishusho irashobora gucapurwa kugirango irebe nyuma.
Ultrasound yo munda. Transducer ya ultrasound ihujwe na mudasobwa inyuzwa hejuru yinda. Ultrasound transducer isubiza amajwi hejuru yingingo zimbere ninyuma kugirango ikore echo ikora sonogramu (ishusho ya mudasobwa).
  • Ikizamini cyimikorere yibihaha (PFT): Ikizamini cyo kureba uko ibihaha bikora neza. Ipima umwuka uhagije ibihaha bishobora gufata nuburyo umwuka wihuta winjira no mu bihaha. Ipima kandi urugero rwa ogisijeni ikoreshwa hamwe na dioxyde de carbone itangwa mugihe cyo guhumeka. Ibi byitwa kandi ibizamini byo gukora ibihaha.
  • Bronchoscopy: Uburyo bwo kureba imbere muri trachea n'inzira nini zo mu bihaha ahantu hadasanzwe. Bronchoscope yinjizwa mumazuru cyangwa umunwa muri trachea no mubihaha. Bronchoscope nigikoresho cyoroshye, gisa nigituba gifite urumuri ninzira yo kureba. Irashobora kandi kuba ifite igikoresho cyo gukuraho ingero za tissue, zisuzumwa munsi ya microscope kugirango ibimenyetso bya kanseri.
  • Endoscopi: Uburyo bwo kureba ingingo nuduce twimbere mumubiri kugirango tumenye ahantu hadasanzwe mumyanya yigifu cyangwa ibihaha. Endoscope yinjizwa mu gutemagura (gukata) mu ruhu cyangwa gufungura mu mubiri, nk'akanwa. Endoscope nigikoresho cyoroshye, kimeze nkigikoresho gifite urumuri na lens yo kureba. Irashobora kandi kuba ifite igikoresho cyo gukuraho ingirangingo cyangwa lymph node ntangarugero, zisuzumwa munsi ya microscope kugirango ibimenyetso byindwara.
  • Biopsy: Gukuraho ingirabuzimafatizo cyangwa ingirabuzimafatizo kugirango zishobore kurebwa munsi ya microscope na patologue kugirango barebe selile LCH. Kugirango umenye LCH, hashobora gukorwa biopsy yamagufa, uruhu, lymph node, umwijima, cyangwa ahandi hantu h’indwara.

Ibintu bimwe bigira ingaruka kubitekerezo (amahirwe yo gukira) hamwe nuburyo bwo kuvura.

LCH mu ngingo nkuruhu, amagufa, node ya lymph, cyangwa glande ya pitoito mubisanzwe bigenda neza hamwe no kuvurwa kandi byitwa "ibyago bike". LCH mu gihimba, umwijima, cyangwa igufwa ryamagufa biragoye kuvura kandi byitwa "ibyago byinshi".

Amahitamo yo kuvura no kuvura biterwa nibi bikurikira:

  • Umurwayi afite imyaka ingahe iyo asuzumwe na LCH.
  • Nibihe bice cyangwa sisitemu yumubiri bigira ingaruka kuri LCH.
  • Ni kangahe ingingo cyangwa sisitemu z'umubiri kanseri ifata.
  • Niba kanseri iboneka mu mwijima, mu gihimba, mu magufa, cyangwa mu magufwa amwe mu gihanga.
  • Nigute kanseri yitabira kwivuza bwambere.
  • Niba hari impinduka zimwe na zimwe muri BRAF.
  • Niba kanseri imaze gupimwa cyangwa yagarutse (byongeye).

Ku mpinja zigera ku mwaka umwe, LCH irashobora kugenda itavuwe.

Icyiciro cya LCH

INGINGO Z'INGENZI

  • Nta sisitemu yo kubika Langerhans selile histiocytose (LCH).
  • Kuvura LCH bishingiye aho selile ya LCH iboneka mumubiri kandi niba LCH ifite ibyago bike cyangwa ibyago byinshi.
  • LCH

Nta sisitemu yo kubika Langerhans selile histiocytose (LCH).

Ingano cyangwa ikwirakwizwa rya kanseri mubisanzwe bisobanurwa nkibyiciro. Nta sisitemu yo kubika LCH.

Kuvura LCH bishingiye aho selile ya LCH iboneka mumubiri kandi niba LCH ifite ibyago bike cyangwa ibyago byinshi.

LCH isobanurwa nk'indwara ya sisitemu imwe cyangwa indwara nyinshi, bitewe na sisitemu z'umubiri zigira ingaruka:

  • Sisitemu imwe LCH: LCH iboneka mugice kimwe cyumubiri cyangwa sisitemu yumubiri cyangwa mugice kirenze kimwe cyurwo rugingo cyangwa sisitemu yumubiri. Amagufwa ni ahantu hasanzwe cyane kugirango LCH iboneke.
  • Multisystem LCH: LCH iboneka mubice bibiri cyangwa byinshi cyangwa sisitemu yumubiri cyangwa irashobora gukwirakwira mumubiri. Sisitemu nyinshi LCH ntisanzwe kuruta sisitemu imwe ya LCH.

LCH irashobora kugira ingaruka kumubiri cyangwa ibyago byinshi:

  • Ibice bifite ibyago bike birimo uruhu, amagufa, ibihaha, lymph node, gastrointestinal tract, glande pitoito, glande ya tiroyide, thymus, na sisitemu yo hagati (CNS).
  • Ibice byugarijwe cyane harimo umwijima, ururenda, n'amagufwa.

LCH

LCH isubiramo ni kanseri yagarutse (garuka) imaze kuvurwa. Kanseri irashobora kugaruka ahantu hamwe cyangwa mu bindi bice byumubiri. Bikunze kwisubiramo mumagufa, ugutwi, uruhu, cyangwa glande ya pitoito. LCH ikunze gusubiramo umwaka nyuma yo guhagarika kwivuza. Iyo LCH isubiramo, irashobora kandi kwitwa reactivation.

Amahitamo yo kuvura Incamake ya LCH

INGINGO Z'INGENZI

  • Hariho uburyo butandukanye bwo kuvura abarwayi bafite Langerhans selile histiocytose (LCH).
  • Abana bafite LCH bagomba gutegurwa nubuvuzi bwitsinda ryabatanga ubuvuzi ninzobere mu kuvura kanseri yo mu bwana.
  • Ubwoko icyenda bwo kuvura busanzwe bukoreshwa:
  • Chimoterapi
  • Kubaga
  • Imiti ivura imirasire
  • Ubuvuzi bwa Photodynamic
  • Immunotherapy
  • Ubuvuzi bugamije
  • Ubundi buryo bwo kuvura ibiyobyabwenge
  • Gutera ingirabuzimafatizo
  • Indorerezi
  • Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.
  • Umuti wa Langerhans selile histiocytose irashobora gutera ingaruka.
  • Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.
  • Abarwayi barashobora kwinjira mu mavuriro mbere, mugihe, cyangwa nyuma yo gutangira kwivuza.
  • Iyo kuvura LCH bihagaze, ibisebe bishya birashobora kugaragara cyangwa ibikomere bishaje birashobora kugaruka.
  • Ibizamini byo gukurikirana birashobora gukenerwa.

Hariho uburyo butandukanye bwo kuvura abarwayi bafite Langerhans selile histiocytose (LCH).

Ubwoko butandukanye bwo kuvura burahari kubarwayi bafite LCH. Bumwe mu buryo busanzwe (ubuvuzi bukoreshwa ubu), kandi bumwe burimo kugeragezwa mubigeragezo byamavuriro. Ikigeragezo kivura ni ubushakashatsi bwakozwe bugamije gufasha kunoza imiti igezweho cyangwa kubona amakuru ku buvuzi bushya ku barwayi ba kanseri. Iyo ibizamini byo kwa muganga byerekana ko ubuvuzi bushya buruta ubuvuzi busanzwe, ubuvuzi bushya bushobora kuba ubuvuzi busanzwe. Igihe cyose bishoboka, abarwayi bagomba kwitabira kwipimisha kwa muganga kugirango bahabwe ubundi buryo bwo kuvura LCH. Ibigeragezo bimwe na bimwe bivura abarwayi batatangiye kuvurwa.

Igeragezwa rya Clinical ririmo kubera mu bice byinshi by'igihugu. Amakuru ajyanye nigeragezwa ryamavuriro arahari kurubuga rwa NCI. Guhitamo ubuvuzi bukwiye nicyemezo kirimo cyane umurwayi, umuryango, hamwe nitsinda ryita kubuzima.

Abana bafite LCH bagomba gutegurwa nubuvuzi bwitsinda ryabatanga ubuvuzi ninzobere mu kuvura kanseri yo mu bwana.

Umuti uzakurikiranwa n’umuganga w’abana oncologue, umuganga winzobere mu kuvura abana barwaye kanseri. Oncologue wabana akorana nabandi batanga ubuvuzi bwabana bato ninzobere mu kuvura abana bafite LCH kandi bazobereye mubice bimwe byubuvuzi. Aba bashobora kuba barimo inzobere zikurikira:

  • Umuganga w'abana.
  • Umuganga ubaga abana.
  • Inzobere mu kuvura indwara z'abana.
  • Imirasire ya oncologue.
  • Neurologue.
  • Endocrinologue.
  • Inzobere mu baforomo b'abana.
  • Inzobere mu gusubiza mu buzima busanzwe.
  • Umuhanga mu by'imitekerereze ya muntu.
  • Ushinzwe imibereho myiza.

Ubwoko icyenda bwo kuvura busanzwe bukoreshwa:

Chimoterapi

Chimoterapi ni umuti wa kanseri ukoresha ibiyobyabwenge kugirango uhagarike imikurire ya kanseri, haba mu kwica selile cyangwa kubabuza gutandukana. Iyo chimiotherapie ifashwe numunwa cyangwa igaterwa mumitsi cyangwa imitsi, imiti yinjira mumaraso kandi irashobora kugera kanseri ya kanseri mumubiri (chimiotherapie sisitemu). Iyo chimiotherapie ishyizwe neza kuruhu cyangwa mumazi ya cerebrospinal, urugingo, cyangwa umwobo wumubiri nkinda, imiti yibasira kanseri ya kanseri muri utwo turere (chimiotherapie yo mukarere).

Chimoterapi irashobora gutangwa mugutera inshinge cyangwa kumunwa cyangwa gukoreshwa kuruhu kugirango bavure LCH.

Kubaga

Kubaga birashobora gukoreshwa mugukuraho ibikomere bya LCH hamwe nuduce duto duto twiza hafi. Curettage ni ubwoko bwo kubaga bukoresha curette (igikoresho gityaye, kimeze nk'ikiyiko) kugirango ukureho selile LCH mu magufa.

Iyo hari umwijima cyangwa ibihaha byangiritse, urugingo rwose rushobora gukurwaho rugasimbuzwa umwijima cyangwa ibihaha bizima kumuterankunga.

Imiti ivura imirasire

Imishwarara ivura ni imiti ikoresha kanseri ikoresha ingufu nyinshi za x-imirasire cyangwa ubundi bwoko bwimirasire yica kanseri cyangwa ikabuza gukura. Imiti ivura hanze ikoresha imashini hanze yumubiri kugirango yohereze imirasire yerekeza kumubiri hamwe na kanseri. Ultraviolet B (UVB) ivura imirasire irashobora gutangwa hifashishijwe itara ridasanzwe riyobora imirasire yanduye uruhu rwa LCH.

Ubuvuzi bwa Photodynamic

Ubuvuzi bwa Photodynamic nubuvuzi bwa kanseri bukoresha ibiyobyabwenge nubwoko runaka bwurumuri rwa laser kugirango bice selile. Umuti udakora kugeza uhuye numucyo utera mumitsi. Umuti ukusanya byinshi muri selile ya kanseri kuruta muri selile zisanzwe. Kuri LCH, urumuri rwa lazeri rugamije uruhu kandi imiti igakora kandi ikica kanseri. Ubuvuzi bwa Photodynamic butera kwangirika kwinyama nzima. Abarwayi bafite imiti ya fotodinamike ntibagomba kumara igihe kinini ku zuba.

Mu bwoko bumwe bwo kuvura Photodynamic, bwitwa psoralen na ultraviolet A (PUVA), umurwayi yakira imiti yitwa psoralen hanyuma ultraviolet Imirasire yerekeza kuruhu.

Immunotherapy

Immunotherapy nubuvuzi bukoresha sisitemu yumubiri yumurwayi kurwanya kanseri. Ibintu bikozwe numubiri cyangwa bikozwe muri laboratoire bikoreshwa mukuzamura, kuyobora, cyangwa kugarura umubiri kamere irinda kanseri. Ubu bwoko bwo kuvura kanseri nabwo bwitwa biotherapy cyangwa biologique therapy. Hariho ubwoko butandukanye bwikingira:

  • Interferon ikoreshwa mu kuvura LCH y'uruhu.
  • Thalidomide ikoreshwa mukuvura LCH.
  • Immunoglobuline yimitsi (IVIG) ikoreshwa mukuvura syndrome ya CNS neurodegenerative.

Ubuvuzi bugamije

Ubuvuzi bugamije ni uburyo bwo kuvura bukoresha ibiyobyabwenge cyangwa ibindi bintu byibasira kanseri. Ubuvuzi bugamije bushobora guteza ingaruka nke kuri selile zisanzwe kuruta chimiotherapie cyangwa imiti ivura imirasire. Hariho ubwoko butandukanye bwo kuvura:

  • Tyrosine kinase inhibitor ibuza ibimenyetso bikenewe kugirango ibibyimba bikure. Tyrosine kinase inhibitor ikoreshwa mu kuvura LCH harimo ibi bikurikira:
  • Imatinib mesylate ihagarika ingirangingo z'amaraso guhinduka ingirabuzimafatizo zishobora guhinduka kanseri.
  • BRAF ibuza poroteyine zikenewe mu mikurire kandi zishobora kwica kanseri. Gene ya BRAF iboneka muburyo bwahinduwe (bwahinduwe) muburyo bumwe na bumwe bwa LCH kandi kuyifunga bishobora gufasha kurinda kanseri gukura.
  • Vemurafenib na dabrafenib ni BRAF inhibitor zikoreshwa mukuvura LCH.
  • Ubuvuzi bwa antibody ya Monoclonal ikoresha antibodies zakozwe muri laboratoire ziva mubwoko bumwe bwimikorere yumubiri. Iyi antibodies irashobora kumenya ibintu biri muri kanseri ya kanseri cyangwa ibintu bisanzwe bishobora gufasha kanseri gukura. Antibodiyite ifata ibintu kandi ikica selile ya kanseri, ikabuza gukura kwayo, cyangwa ikabuza gukwirakwira. Bashobora gukoreshwa bonyine cyangwa gutwara ibiyobyabwenge, uburozi, cyangwa ibikoresho bya radio bikoresha kanseri ya kanseri. Antibodiyite za Monoclonal zitangwa no gushiramo.
  • Rituximab ni antibody ya monoclonal ikoreshwa mu kuvura LCH.

Ubundi buryo bwo kuvura ibiyobyabwenge

Ibindi biyobyabwenge bikoreshwa mu kuvura LCH birimo ibi bikurikira:

  • Ubuvuzi bwa Steroide, nka prednisone, bukoreshwa mu kuvura ibikomere bya LCH.
  • Ubuvuzi bwa Bisphosifone (nka pamidronate, zoledronate, cyangwa alendronate) bukoreshwa mu kuvura ibikomere bya LCH byo mu magufa no kugabanya ububabare bw'amagufwa.
  • Imiti igabanya ubukana ni ibiyobyabwenge (nka pioglitazone na rofecoxib) bikunze gukoreshwa mu kugabanya umuriro, kubyimba, kubabara, no gutukura. Imiti igabanya ubukana hamwe na chimiotherapie irashobora gutangwa hamwe kugirango bavure abantu bakuru bafite amagufwa LCH.
  • Retinoide, nka isotretinoin, ni imiti ijyanye na vitamine A ishobora kugabanya umuvuduko w'ingirabuzimafatizo za LCH mu ruhu. Retinoide ifatwa kumunwa.

Gutera ingirabuzimafatizo

Gutera ingirabuzimafatizo ni uburyo bwo gutanga chimiotherapie no gusimbuza uturemangingo dukora amaraso twangijwe no kuvura LCH. Ingirabuzimafatizo (selile zidakuze) zivanwa mumaraso cyangwa igufwa ryumurwayi cyangwa umuterankunga hanyuma bikonjeshwa bikabikwa. Nyuma ya chimiotherapie irangiye, ingirangingo zibitswe zabitswe hanyuma zisubizwa umurwayi binyuze mu gushiramo. Izi ngirabuzimafatizo zongeye gukoreshwa zikura (kandi zigarura) ingirangingo z'amaraso z'umubiri.

Indorerezi

Indorerezi ikurikiranira hafi imiterere yumurwayi idatanga imiti kugeza ibimenyetso cyangwa ibimenyetso bigaragara cyangwa bihindutse.

Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.

Amakuru yerekeye ibizamini byamavuriro araboneka kurubuga rwa NCI.

Umuti wa Langerhans selile histiocytose irashobora gutera ingaruka.

Kumakuru yingaruka zitangira mugihe cyo kuvura kanseri, reba urupapuro rwuruhande rwacu.

Ingaruka ziterwa no kuvura kanseri zitangira nyuma yo kuvurwa zikomeza amezi cyangwa imyaka byitwa ingaruka zitinze. Ingaruka zo kuvura kanseri zishobora kuba zikubiyemo ibi bikurikira:

  • Gutinda gukura niterambere.
  • Kubura kumva.
  • Amagufa, iryinyo, umwijima, nibihaha.
  • Guhinduka mumyumvire, kumva, kwiga, gutekereza, cyangwa kwibuka.
  • Kanseri ya kabiri, nka leukemia, retinoblastoma, Ewing sarcoma, ubwonko cyangwa kanseri y'umwijima.

Ingaruka zimwe zitinze zishobora kuvurwa cyangwa kugenzurwa. Ni ngombwa kuganira n'abaganga b'umwana wawe ku ngaruka kuvura kanseri bishobora kugira ku mwana wawe. (Reba incamake ya ku ngaruka zitinze zo kuvura kanseri y'abana kugira ngo umenye amakuru.)

Abarwayi benshi bafite sisitemu nyinshi LCH bafite ingaruka zitinze ziterwa no kuvurwa cyangwa nindwara ubwayo. Aba barwayi bakunze kugira ibibazo byubuzima bwigihe kirekire bigira ingaruka kumibereho yabo.

Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.

Ku barwayi bamwe, kwitabira ikizamini cyamavuriro birashobora kuba uburyo bwiza bwo kuvura. Ibigeragezo bivura biri mubikorwa byubushakashatsi bwa kanseri. Igeragezwa rya Clinical rikorwa kugirango hamenyekane niba imiti mishya ya kanseri itekanye kandi ifite akamaro cyangwa nziza kuruta ubuvuzi busanzwe.

Benshi mubuvuzi busanzwe bwa kanseri bushingiye kubigeragezo byambere byubuvuzi. Abarwayi bitabiriye kwipimisha barashobora kuvurwa bisanzwe cyangwa kuba mubambere bahawe imiti mishya.

Abarwayi bitabira ibizamini byo kwa muganga nabo bafasha kunoza uburyo kanseri izavurwa mugihe kizaza. Nubwo ibigeragezo bivura bitaganisha ku buvuzi bushya, akenshi basubiza ibibazo byingenzi kandi bigafasha gutera imbere ubushakashatsi.

Abarwayi barashobora kwinjira mu mavuriro mbere, mugihe, cyangwa nyuma yo gutangira kwivuza.

Igeragezwa rimwe na rimwe ririmo abarwayi bataravurwa. Ibindi bigeragezo bipima abarwayi bafite kanseri itameze neza. Hariho kandi ibizamini byo kwa muganga bipima uburyo bushya bwo guhagarika kanseri kongera kugaruka (kugaruka) cyangwa kugabanya ingaruka zo kuvura kanseri.

Igeragezwa rya Clinical ririmo kubera mu bice byinshi by'igihugu. Amakuru yerekeye ibizamini byamavuriro ashyigikiwe na NCI urashobora kubisanga kurubuga rwa NCI. Ibizamini bya Clinical bishyigikiwe nandi mashyirahamwe murashobora kubisanga kurubuga rwa ClinicalTrials.gov.

Iyo kuvura LCH bihagaze, ibisebe bishya birashobora kugaragara cyangwa ibikomere bishaje birashobora kugaruka.

Abarwayi benshi bafite LCH bakira neza hamwe no kuvurwa. Ariko, mugihe ubuvuzi buhagaze, ibisebe bishya birashobora kugaragara cyangwa ibikomere bishaje birashobora kugaruka. Ibi byitwa reactivation (repetrence) kandi birashobora kubaho mugihe cyumwaka umwe nyuma yo guhagarika kwivuza. Abarwayi barwaye sisitemu nyinshi barashobora kugira reaction. Imbuga zisanzwe zo kongera gukora ni amagufwa, ugutwi, cyangwa uruhu. Indwara ya diyabete nayo irashobora gukura. Imbuga nke zisanzwe zo gukora reaction zirimo lymph node, marrow, amagufa, umwijima, cyangwa ibihaha. Bamwe mu barwayi barashobora kugira reaction zirenze imwe mumyaka itari mike.

Ibizamini byo gukurikirana birashobora gukenerwa.

Kubera ibyago byo kongera gukora, abarwayi ba LCH bagomba gukurikiranwa imyaka myinshi. Bimwe mubizamini byakozwe mugupima LCH birashobora gusubirwamo. Nukureba uburyo ubuvuzi bukora neza kandi niba hari ibikomere bishya. Ibi bizamini birashobora kubamo:

  • Ikizamini cyumubiri.
  • Ikizamini cya Neurologiya.
  • Ikizamini cya Ultrasound.
  • MRI.
  • CT scan.
  • PET scan.

Ibindi bizamini bishobora gukenerwa harimo:

  • Ubwonko bwubwonko bwabyukije igisubizo (BAER) ikizamini: Ikizamini gipima igisubizo cyubwonko bwo gukanda amajwi cyangwa amajwi amwe.
  • Ikizamini cyimikorere yibihaha (PFT): Ikizamini cyo kureba uko ibihaha bikora neza. Ipima umwuka uhagije ibihaha bishobora gufata nuburyo umwuka wihuta winjira mu bihaha. Ipima kandi urugero rwa ogisijeni ikoreshwa hamwe na dioxyde de carbone itangwa mugihe cyo guhumeka. Ibi byitwa kandi ibizamini byo gukora ibihaha.
  • Isanduku x-ray: X-ray yingingo namagufwa imbere yigituza. X-ray ni ubwoko bwingufu zishobora kunyura mumubiri no kuri firime, bigakora ishusho yibice byumubiri.

Ibisubizo by'ibi bizamini birashobora kwerekana niba ubuzima bwawe bwarahindutse cyangwa niba kanseri yarongeye (garuka). Ibi bizamini rimwe na rimwe byitwa gukurikirana-ibizamini cyangwa kugenzura. Ibyemezo bijyanye no gukomeza, guhindura, cyangwa guhagarika ubuvuzi birashobora gushingira kubisubizo byibi bizamini.

Kuvura ibyago bike LCH mubana

Muri iki gice

  • Uruhu
  • Ibibyimba mu magufa cyangwa izindi nzego zifite ibyago bike
  • CNS

Kumakuru yerekeye imiti yavuzwe hepfo, reba igice cyo kuvura.

Uruhu

Kuvura ibibyimba bishya bya Langerhans selile histiocytose (LCH) ibikomere byuruhu bishobora kubamo:

  • Indorerezi.

Iyo habaye uburibwe bukabije, ububabare, ibisebe, cyangwa kuva amaraso, kuvura bishobora kuba bikubiyemo ibi bikurikira:

  • Ubuvuzi bwa Steroid.
  • Chimoterapi itangwa kumunwa cyangwa imitsi.
  • Chimiotherapie ikoreshwa kuruhu.
  • Ubuvuzi bwa Photodynamic hamwe na psoralen na ultraviolet A (PUVA).
  • UVB ivura imirasire.

Ibibyimba mu magufa cyangwa izindi nzego zifite ibyago bike

Kuvura ibibyimba bishya byavutse mu bwana LCH amagufwa imbere, impande, cyangwa inyuma ya gihanga, cyangwa mumagufwa yose ashobora kuba arimo:

  • Kubaga (curettage) hamwe nubuvuzi bwa steroid.
  • Imiti ikabije yo kuvura imishwarara yibasira ingingo zegeranye.

Kuvura ibisebe bishya byabana bato LCH mumagufwa akikije amatwi cyangwa amaso bikorwa kugirango bigabanye ibyago byo kurwara diyabete insipidus nibindi bibazo byigihe kirekire. Umuti urashobora kubamo:

  • Chimiotherapie hamwe nubuvuzi bwa steroid.
  • Kubaga (curettage).

Kuvura ibisebe bishya byabana LCH ibikomere byumugongo cyangwa amagufwa yibibero bishobora kubamo:

  • Indorerezi.
  • Kuvura imishwarara mike.
  • Chimoterapi, kubisebe bikwirakwira mu ruti rw'umugongo.
  • Kubaga kugirango ukomeze igufwa ryacitse intege mugukata cyangwa guhuza amagufwa hamwe.

Kuvura ibikomere bibiri cyangwa byinshi birashobora kuba birimo:

  • Chimiotherapie hamwe nubuvuzi bwa steroid.

Kuvura ibikomere bibiri cyangwa byinshi byamagufwa hamwe nindwara zuruhu, lymph node ibikomere, cyangwa insipidus ya diabete irashobora kubamo:

  • Chimoterapi hamwe nubuvuzi bwa steroid.
  • Ubuvuzi bwa Bisphosifone.

CNS

Kuvura ibibyimba bishya byavutse mu bwana LCH central nervous system (CNS) ibikomere bishobora kubamo:

  • Chimoterapi hamwe nubuvuzi bwa steroid.

Kuvura syndrome ya LCH CNS ya neurodegenerative syndrome irashobora kubamo:

  • Ubuvuzi bugamije hamwe na BRAF inhibitor (vemurafenib cyangwa dabrafenib).
  • Chimoterapi.
  • Ubuvuzi bugamije hamwe na antibody ya monoclonal (rituximab).
  • Ubuvuzi bwa Retinoid.
  • Immunotherapy (IVIG) hamwe na chimiotherapie cyangwa idafite.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Kuvura ibyago byinshi LCH mubana

Kumakuru yerekeye imiti yavuzwe hepfo, reba igice cyo kuvura.

Kuvura indwara zimaze kuvuka mu bwana LCH multisystem indwara zanduye mu gihimba, umwijima, cyangwa igufwa ryamagufa nurundi rugingo cyangwa urubuga rushobora kubamo:

  • Chimiotherapie hamwe nubuvuzi bwa steroid. Umubare munini wimiti irenze imwe ya chimiotherapie hamwe nubuvuzi bwa steroid birashobora guhabwa abarwayi bafite ibibyimba bititabira chimiotherapie yambere.
  • Ubuvuzi bugamije (vemurafenib).
  • Guhindura umwijima kubarwayi bafite umwijima ukabije.
  • Ikigeragezo kivura kijyanye no kuvura umurwayi hashingiwe ku biranga kanseri n'uburyo yitabira kwivuza.
  • Ikigeragezo cyamavuriro ya chimiotherapie hamwe nubuvuzi bwa steroid.

Umuti wo Gusubiramo, Kwanga, no Gutera Imbere Ubwana LCH mubana

Kumakuru yerekeye imiti yavuzwe hepfo, reba igice cyo kuvura.

LCH isubiramo ni kanseri idashobora kumenyekana mugihe runaka nyuma yo kuvurwa hanyuma ikagaruka. Refractory LCH ni kanseri idakira neza hamwe no kuvura. Iterambere LCH ni kanseri ikomeza kwiyongera mugihe cyo kuvura.

Umuti wisubiramo, wanze, cyangwa ugenda utera ibyago bike LCH irashobora kubamo:

  • Chimoterapi hamwe nubuvuzi bwa steroid.
  • Ubuvuzi bwa Bisphosifone.

Kuvura inshuro nyinshi, kwanga, cyangwa gutera imbere cyane ibyago byinshi sisitemu LCH irashobora kubamo:

  • Chimiotherapie ikabije.
  • Ubuvuzi bugamije (vemurafenib).
  • Gutera ingirabuzimafatizo.

Ubuvuzi burimo kwigwa kubisubiramo, byanze bikunze, cyangwa iterambere ryabana bato LCH harimo ibi bikurikira:

  • Ikigeragezo kivura kijyanye no kuvura umurwayi hashingiwe ku biranga kanseri n'uburyo yitabira kwivuza.
  • Igeragezwa rya clinique risuzuma icyitegererezo cyibibyimba byumurwayi kugirango hahindurwe gene. Ubwoko bwo kuvura bugenewe umurwayi biterwa n'ubwoko bw'imihindagurikire ya gene.

Kuvura LCH mubantu bakuru

Muri iki gice

  • Kuvura LCH y'ibihaha mubantu bakuru
  • Kuvura LCH yamagufa mubantu bakuru
  • Kuvura LCH y'uruhu mubantu bakuru
  • Ubuvuzi bwa Sisitemu imwe na sisitemu nyinshi LCH mubantu bakuru

Kumakuru yerekeye imiti yavuzwe hepfo, reba igice cyo kuvura

Langerhans selile histiocytose (LCH) mubantu bakuze ni nka LCH mubana kandi irashobora gukora mubice bimwe na sisitemu nkuko bikorwa mubana. Harimo sisitemu ya endocrine na nervice yo hagati, umwijima, impyiko, igufwa ryamagufa, hamwe na gastrointestinal tract. Ku bantu bakuru, LCH ikunze kuboneka mu bihaha nk'indwara ya sisitemu imwe. LCH mu bihaha ibaho kenshi mubakuze bakuze banywa itabi. Abakuze LCH nayo ikunze kuboneka mumagufa cyangwa uruhu.

Kimwe no mu bana, ibimenyetso n'ibimenyetso bya LCH biterwa n'aho iboneka mu mubiri. Reba Ibisobanuro Rusange kubimenyetso nibimenyetso bya LCH.

Ibizamini bisuzuma ingingo na sisitemu yumubiri aho LCH ishobora kugaragara bikoreshwa mugushakisha (gushakisha) no gusuzuma LCH. Reba Ibisobanuro Rusange Igice cyibizamini nuburyo bukoreshwa mugupima LCH.

Ku bantu bakuru, nta makuru menshi yerekeye icyo kuvura bikora neza. Rimwe na rimwe, amakuru aturuka gusa kuri raporo zo gusuzuma, kuvura, no gukurikirana umuntu mukuru cyangwa itsinda rito ry'abantu bakuru bahawe ubuvuzi bumwe.

Kuvura LCH y'ibihaha mubantu bakuru

Umuti wa LCH y'ibihaha mubantu bakuru urashobora kubamo:

  • Kureka itabi kubarwayi bose banywa itabi. Kwangirika kw'ibihaha bizagenda byiyongera uko igihe kigenda gihita mu barwayi batareka itabi. Ku barwayi baretse kunywa itabi, kwangirika kw'ibihaha birashobora kuba byiza cyangwa birashobora kuba bibi mu gihe runaka.
  • Chimoterapi.
  • Guhindura ibihaha ku barwayi bafite ibihaha bikabije.

Rimwe na rimwe, LCH y'ibihaha izashira cyangwa ntizabe mibi nubwo itavuwe.

Kuvura LCH yamagufa mubantu bakuru

Ubuvuzi bwa LCH bugira ingaruka kumagufa gusa mubantu bakuru bushobora kubamo:

  • Kubaga hamwe no kuvura steroid.
  • Chimiotherapie hamwe cyangwa idafite imiti mike yo kuvura imishwarara.
  • Imiti ivura imirasire.
  • Ubuvuzi bwa Bisphosphonate, kubabara amagufwa akomeye.
  • Imiti igabanya ubukana hamwe na chimiotherapie.

Kuvura LCH y'uruhu mubantu bakuru

Umuti wa LCH wibasira uruhu gusa mubantu bakuru urashobora kubamo:

  • Kubaga.
  • Steroid cyangwa ubundi buryo bwo kuvura imiti ikoreshwa cyangwa yatewe mu ruhu.
  • Ubuvuzi bwa Photodynamic hamwe nimirasire ya psoralen na ultraviolet A (PUVA).
  • UVB ivura imirasire.
  • Chimiotherapie cyangwa immunotherapy itangwa numunwa, nka methotrexate, thalidomide, hydroxyurea, cyangwa interferon.
  • Ubuvuzi bwa Retinoid burashobora gukoreshwa mugihe ibikomere byuruhu bitameze neza hamwe nubundi buvuzi.

Umuti wa LCH ugira ingaruka kuruhu nubundi buryo bwumubiri mubantu bakuru ushobora kubamo:

  • Chimoterapi.

Ubuvuzi bwa Sisitemu imwe na sisitemu nyinshi LCH mubantu bakuru

Kuvura indwara ya sisitemu imwe na sisitemu nyinshi kubantu bakuze bitagira ingaruka ku bihaha, amagufwa, cyangwa uruhu bishobora kubamo:

  • Chimoterapi.
  • Ubuvuzi bugamije (imatinib, cyangwa vemurafenib).

Kubindi bisobanuro kubyerekeye ibigeragezo bya LCH kubantu bakuru, reba urubuga rwa HistiocyteExit Disclaimer urubuga.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Kugira ngo umenye byinshi kuri Langerhans Cell Histiocytose

Ushaka amakuru menshi yikigo cyigihugu gishinzwe kanseri kubyerekeye Langerhans selile histiocytose, reba ibi bikurikira:

  • Kubara Tomografiya (CT) Gusikana na Kanseri
  • Ubuvuzi bwa Photodynamic kuri Kanseri
  • Immunotherapy yo kuvura Kanseri
  • Intego zo kuvura Kanseri
  • Gutera Amaraso Yimitsi Yimitsi

Kubindi bisobanuro bya kanseri yo mu bwana hamwe nubundi buryo rusange bwa kanseri, reba ibi bikurikira:

  • Ibyerekeye Kanseri
  • Kanseri yo mu bwana
  • Umuti wo Gushakisha Kanseri Yabana Kureka
  • Ingaruka Zitinze Kuvura Kanseri Yabana
  • Ingimbi n'abangavu bafite kanseri
  • Abana barwaye Kanseri: Imfashanyigisho ku babyeyi
  • Kanseri mu bana n'ingimbi
  • Gutegura
  • Guhangana na Kanseri
  • Ibibazo byo Kubaza Muganga wawe kuri Kanseri
  • Abacitse ku icumu n'abarezi


Ongeraho igitekerezo cyawe
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