Types/kidney/patient/kidney-treatment-pdq

Kuvura Kanseri Yimpyiko (®) - Indwara yabarwayi

Amakuru Rusange Yerekeye Kanseri Yimpyiko

INGINGO Z'INGENZI

• Kanseri y'impyiko ni indwara ingirabuzimafatizo (kanseri) ziba mu tubari twimpyiko.

• Kunywa itabi no gukoresha nabi imiti imwe n'imwe y'ububabare birashobora kugira ingaruka kuri kanseri y'impyiko.

• Ibimenyetso bya kanseri y'impyiko zirimo amaraso mu nkari hamwe n'ikibyimba mu nda.

• Ibizamini bisuzuma inda nimpyiko bikoreshwa mugupima kanseri yimpyiko.

• Ibintu bimwe bigira ingaruka kubitekerezo (amahirwe yo gukira) hamwe nuburyo bwo kuvura.

Kanseri y'impyiko ni indwara ingirabuzimafatizo (kanseri) ziba mu tubari twimpyiko.

Kanseri y'impyiko (nanone yitwa kanseri y'impyiko cyangwa adenocarcinoma y'impyiko) ni indwara aho ingirabuzimafatizo (kanseri) ziboneka mu murongo w'igituba (utubuto duto cyane) mu mpyiko. Hariho impyiko 2, imwe kuruhande rwumugongo, hejuru yumukondo. Utubuto duto mu mpyiko zungurura kandi usukure amaraso. Bakuramo imyanda bakora inkari. Inkari zinyura muri buri mpyiko zinyuze mu muyoboro muremure witwa ureter mu ruhago. Uruhago rufata inkari kugeza zinyuze muri urethra zikava mu mubiri.

Anatomy ya sisitemu yinkari zabagabo (panne ibumoso) na sisitemu yinkari zumugore (panne iburyo) yerekana impyiko, ureteri, uruhago, na urethra. Inkari zakozwe mu tubari twimpyiko kandi zegeranya mu mpyiko za buri mpyiko. Inkari zitemba ziva mu mpyiko zinyuze mu nkari zigana mu ruhago. Inkari zibikwa mu ruhago kugeza ziva mu mubiri zinyuze muri urethra.

Kanseri itangirira muri ureter cyangwa impyiko (igice cyimpyiko ikusanya inkari ikayijugunya kuri ureter) itandukanye na kanseri yimpyiko. .

Kunywa itabi no gukoresha nabi imiti imwe n'imwe y'ububabare birashobora kugira ingaruka kuri kanseri y'impyiko.

Ikintu cyose cyongera ibyago byo kwandura byitwa impanuka. Kugira ibintu bishobora guteza ibyago ntibisobanura ko uzarwara kanseri; kutagira ibyago bishobora gusobanura ko utazarwara kanseri. Vugana na muganga wawe niba utekereza ko ushobora guhura n'akaga.

Impamvu zishobora gutera kanseri yimpyiko zirimo ibi bikurikira:

• Kunywa itabi.

• Gukoresha nabi imiti imwe yububabare, harimo imiti irenga ububabare, igihe kirekire.

• Kugira umubyibuho ukabije.

• Kugira umuvuduko ukabije w'amaraso.

• Kugira amateka yumuryango wa kanseri yimpyiko.

• Kugira imiterere imwe n'imwe, nk'indwara ya von Hippel-Lindau cyangwa kanseri y'impyiko ya kanseri.

Ibimenyetso bya kanseri y'impyiko zirimo amaraso mu nkari ndetse n'ikibyimba mu nda. '

Ibi bimenyetso nibindi bimenyetso bishobora guterwa na kanseri yimpyiko cyangwa nibindi bihe. Ntabwo hashobora kubaho ibimenyetso cyangwa ibimenyetso mubyiciro byambere. Ibimenyetso nibimenyetso bishobora kugaragara uko ikibyimba gikura. Menyesha umuganga wawe niba ufite kimwe muri ibi bikurikira:

• Amaraso mu nkari.

• Ikibyimba mu nda.

• Ububabare kuruhande butagiye.

• Kubura ubushake bwo kurya.

• Kugabanya ibiro nta mpamvu izwi.

• Anemia.

Ibizamini bisuzuma inda nimpyiko bikoreshwa mugupima kanseri yimpyiko.

Ibizamini hamwe nuburyo bukurikira birashobora gukoreshwa:

• Ikizamini cyumubiri namateka yubuzima: Ikizamini cyumubiri kugirango ugenzure ibimenyetso rusange byubuzima, harimo no gusuzuma ibimenyetso byindwara, nkibibyimba cyangwa ikindi kintu cyose gisa nkidasanzwe. Hazafatwa kandi amateka yubuzima bwumurwayi nindwara zashize hamwe nubuvuzi.

• Ikizamini cya Ultrasound: Uburyo bukoreshwa mu majwi menshi y’amajwi (ultrasound) asohoka mu ngingo cyangwa mu ngingo imbere hanyuma agasubiramo. Ijwi ryerekana ishusho yumubiri wumubiri witwa sonogram.

• Ubushakashatsi bwa chimie yamaraso: Uburyo bwo gusuzuma urugero rwamaraso kugirango bapime urugero rwibintu bimwe na bimwe bisohoka mumaraso ningingo nuduce twumubiri. Umubare udasanzwe (uri hejuru cyangwa uri munsi yubusanzwe) ibintu bishobora kuba ikimenyetso cyindwara.

• Urinalysis: Ikizamini cyo gusuzuma ibara ry'inkari n'ibiyirimo, nk'isukari, proteyine, selile zitukura, na selile yera.

• CT scan (CAT scan): Uburyo bukora urukurikirane rwamashusho arambuye yibice byimbere mumubiri, nkinda ninda, byafashwe muburyo butandukanye. Amashusho yakozwe na mudasobwa ihujwe na mashini ya x-ray. Irangi rishobora guterwa mumitsi cyangwa kumirwa kugirango bifashe ingingo cyangwa ingirangingo kugaragara neza. Ubu buryo nabwo bwitwa computing tomografiya, tomografiya ya mudasobwa, cyangwa mudasobwa ya axial tomografiya.

• MRI . Ubu buryo bwitwa kandi magnetic magnetic resonance imaging (NMRI).

• Biopsy: Gukuraho ingirabuzimafatizo cyangwa ingirangingo kugirango zishobore kurebwa munsi ya microscope na patologue kugirango barebe ibimenyetso bya kanseri. Kugirango ukore biopsy ya kanseri yimpyiko, urushinge ruto rwinjizwa mu kibyimba hanyuma hakurwamo icyitegererezo cya tissue.

Ibintu bimwe bigira ingaruka kubitekerezo (amahirwe yo gukira) hamwe nuburyo bwo kuvura.

Amahitamo yo kuvura no kuvura biterwa nibi bikurikira:

• Intambwe yindwara.

• Imyaka yumurwayi nubuzima rusange.

Icyiciro cya Kanseri Yimpyiko

INGINGO Z'INGENZI

• Nyuma yo gupimwa kanseri y'impyiko, hakozwe ibizamini kugirango hamenyekane niba kanseri yakwirakwiriye mu mpyiko cyangwa mu bindi bice by'umubiri.

• Hariho uburyo butatu kanseri ikwirakwira mu mubiri.

• Kanseri irashobora gukwirakwira aho yatangiriye no mu bindi bice byumubiri.

• Ibyiciro bikurikira bikoreshwa muri kanseri yimpyiko:

• Icyiciro I.

• Icyiciro cya II

• Icyiciro cya III

• Icyiciro cya IV

• Kanseri y'impyiko irashobora kugaruka (kugaruka) nyuma yimyaka myinshi nyuma yo kuvurwa bwa mbere.

Nyuma yo gupimwa kanseri y'impyiko, hakozwe ibizamini kugirango hamenyekane niba kanseri yakwirakwiriye mu mpyiko cyangwa mu bindi bice by'umubiri.

Inzira ikoreshwa mu kumenya niba kanseri yarakwirakwiriye mu mpyiko cyangwa mu bindi bice by'umubiri byitwa guterana. Amakuru yakusanyirijwe mubikorwa byateguwe agena icyiciro cyindwara. Ni ngombwa kumenya icyiciro kugirango utegure kuvura. Ibizamini hamwe nuburyo bukurikira birashobora gukoreshwa mugutegura:

• CT scan (CAT scan): Uburyo bukora urukurikirane rwamashusho arambuye yibice byimbere mumubiri, nkigituza cyangwa ubwonko, byafashwe muburyo butandukanye. Amashusho yakozwe na mudasobwa ihujwe na mashini ya x-ray. Irangi rishobora guterwa mumitsi cyangwa kumirwa kugirango bifashe ingingo cyangwa ingirangingo kugaragara neza. Ubu buryo nabwo bwitwa computing tomografiya, tomografiya ya mudasobwa, cyangwa mudasobwa ya axial tomografiya.

• MRI . Ubu buryo bwitwa kandi magnetic magnetic resonance imaging (NMRI).

• Isanduku x-ray: X-ray yingingo namagufwa imbere yigituza. X-ray ni ubwoko bwingufu zishobora kunyura mumubiri no kuri firime, bigakora ishusho yibice byumubiri.

• Gusikana amagufwa: Uburyo bwo kugenzura niba mu magufwa hari selile zigabanya vuba, nka selile kanseri. Umubare muto cyane wibikoresho bya radio bitera mumitsi kandi bikanyura mumaraso. Ibikoresho bya radiyoyakusanyiriza mu magufa hamwe na kanseri kandi bigaragazwa na scaneri.

Hariho uburyo butatu kanseri ikwirakwira mu mubiri.

Kanseri irashobora gukwirakwira binyuze mu ngingo, sisitemu ya lymph, n'amaraso:

• Tissue. Kanseri ikwirakwira aho yatangiriye ikurira mu turere twegereye.

• Sisitemu ya Lymph. Kanseri ikwirakwira aho yatangiriye yinjira muri sisitemu ya lymph. Kanseri inyura mu mitsi ya lymph igana mu bindi bice by'umubiri.

• Amaraso. Kanseri ikwirakwira aho yatangiriye yinjira mu maraso. Kanseri inyura mu mitsi y'amaraso igana mu bindi bice by'umubiri.

Kanseri irashobora gukwirakwira aho yatangiriye no mu bindi bice byumubiri.

Iyo kanseri ikwirakwira mu kindi gice cy'umubiri, yitwa metastasis. Ingirabuzimafatizo za kanseri zitandukana aho zatangiriye (ikibyimba kibanza) zikanyura muri sisitemu ya lymph cyangwa maraso.

• Sisitemu ya Lymph. Kanseri yinjira muri sisitemu ya lymph, ikanyura mu mitsi ya lymph, igakora ikibyimba (ikibyimba metastatike) mu kindi gice cy'umubiri.

• Amaraso. Kanseri yinjira mu maraso, ikanyura mu mitsi y'amaraso, igakora ikibyimba (ikibyimba metastatike) mu kindi gice cy'umubiri.

Ikibyimba metastatike nubwoko bumwe bwa kanseri nkibibyimba byibanze. Kurugero, niba kanseri yimpyiko ikwirakwira kumagufwa, kanseri yo mumagufwa mubyukuri ni kanseri yimpyiko. Indwara ni kanseri y'impyiko metastatike, ntabwo ari kanseri y'amagufwa.

Ibyiciro bikurikira bikoreshwa muri kanseri yimpyiko:

Icyiciro I.

Icyiciro cya I Kanseri y'impyiko. Ikibyimba gifite santimetero 7 cyangwa ntoya kandi kiboneka mu mpyiko gusa.

Mu cyiciro cya I, ikibyimba gifite santimetero 7 cyangwa ntoya kandi kiboneka mu mpyiko gusa.

Icyiciro cya II

Icyiciro cya II kanseri y'impyiko. Ikibyimba kirenze santimetero 7 kandi kiboneka mu mpyiko gusa.

Mu cyiciro cya II, ikibyimba kirenze santimetero 7 kandi kiboneka mu mpyiko gusa.

Icyiciro cya III

Icyiciro cya III kanseri y'impyiko. Kanseri yo mu mpyiko ni nini kandi kanseri yakwirakwiriye a) hafi ya lymph node, b) imiyoboro y'amaraso iri mu mpyiko cyangwa hafi yayo (impyiko z'impyiko cyangwa vena cava), c) imiterere y'impyiko ikusanya inkari, cyangwa d ) urwego rwamavuta yuzuye impyiko.

Mu cyiciro cya III, kimwe muri ibi bikurikira kiboneka:

• kanseri mu mpyiko nubunini bwose kandi kanseri yakwirakwiriye hafi ya lymph node; cyangwa

• kanseri yakwirakwiriye mu miyoboro y'amaraso mu mpyiko cyangwa hafi yayo (impyiko z'impyiko cyangwa vena cava), ku binure bikikije imiterere y'impyiko ikusanya inkari, cyangwa ku gipimo cy'amavuta akikije impyiko. Kanseri irashobora gukwirakwira hafi ya lymph node.

Icyiciro cya IV

Icyiciro cya IV kanseri y'impyiko. Kanseri yakwirakwiriye a) irenze igipimo cy'amavuta akikije impyiko kandi ishobora kuba yarakwirakwiriye muri glande ya adrenal hejuru y'impyiko na kanseri, cyangwa b) mu bindi bice by'umubiri, nk'ubwonko, ibihaha, umwijima, glande ya adrenal, amagufwa, cyangwa lymph node ya kure.

Mu cyiciro cya IV, kimwe muri ibi bikurikira kiboneka:

• kanseri yakwirakwiriye hejuru y'uruhu rw'amavuta akikije impyiko kandi ishobora kuba yarakwirakwiriye muri glande ya adrenal iri hejuru y'impyiko hamwe na kanseri cyangwa hafi ya lymph node; cyangwa

• kanseri yakwirakwiriye mu bindi bice by'umubiri, nk'amagufwa, umwijima, ibihaha, ubwonko, glande ya adrenal, cyangwa lymph node ya kure.

Kanseri y'impyiko irashobora kugaruka (kugaruka) nyuma yimyaka myinshi nyuma yo kuvurwa bwa mbere.

Kanseri irashobora kugaruka mu mpyiko cyangwa mu bindi bice by'umubiri.

Incamake yo kuvura

INGINGO Z'INGENZI

• Hariho uburyo butandukanye bwo kuvura abarwayi ba kanseri yimpyiko.

• Ubwoko butanu bwo kuvura busanzwe bukoreshwa:

• Kubaga

• Imiti ivura imirasire

• Chimoterapi

• Immunotherapy

• Ubuvuzi bugamije

• Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.

• Umuti wa kanseri yimpyiko urashobora gutera ingaruka.

• Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.

• Abarwayi barashobora kwipimisha kwa muganga mbere, mugihe, cyangwa nyuma yo gutangira kuvura kanseri.

• Ibizamini byo gukurikirana birashobora gukenerwa.

Hariho uburyo butandukanye bwo kuvura abarwayi ba kanseri yimpyiko.

Ubwoko butandukanye bwo kuvura burahari kubarwayi barwaye kanseri yimpyiko. Bumwe mu buryo busanzwe (ubuvuzi bukoreshwa ubu), kandi bumwe burimo kugeragezwa mubigeragezo byamavuriro. Ikigeragezo kivura ni ubushakashatsi bwakozwe bugamije gufasha kunoza imiti igezweho cyangwa kubona amakuru ku buvuzi bushya ku barwayi ba kanseri. Iyo ibizamini byo kwa muganga byerekana ko ubuvuzi bushya buruta ubuvuzi busanzwe, ubuvuzi bushya bushobora kuba ubuvuzi busanzwe. Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga. Ibigeragezo bimwe na bimwe bivura abarwayi batatangiye kwivuza.

Ubwoko butanu bwo kuvura busanzwe bukoreshwa:

Kubaga

Kubaga kugirango ukure igice cyangwa impyiko zose zikoreshwa mugukiza kanseri yimpyiko. Ubwoko bukurikira bwo kubaga bushobora gukoreshwa:

• Nephrectomy igice: Uburyo bwo kubaga kugirango ukureho kanseri iri mu mpyiko na zimwe mu ngingo ziyikikije. Nephrectomy igice irashobora gukorwa kugirango wirinde gutakaza imikorere yimpyiko mugihe izindi mpyiko zangiritse cyangwa zimaze gukurwaho.

• Nephrectomy yoroshye: Uburyo bwo kubaga gukuramo impyiko gusa.

• Nephrectomy ikabije: Uburyo bwo kubaga gukuramo impyiko, glande ya adrenal, ingirangingo zikikije, kandi, mubisanzwe, hafi ya lymph node.

Umuntu arashobora kubana nigice cyimpyiko 1 ikora, ariko niba impyiko zombi zavanyweho cyangwa zidakora, umuntu azakenera dialyse (inzira yo koza amaraso akoresheje imashini hanze yumubiri) cyangwa guhinduranya impyiko (gusimburwa nubuzima bwiza impyiko). Guhindura impyiko birashobora gukorwa mugihe indwara iri mumpyiko gusa kandi impyiko yatanzwe irashobora kuboneka. Niba umurwayi agomba gutegereza impyiko yatanzwe, ubundi buvuzi butangwa nkuko bikenewe.

Iyo kubagwa gukuraho kanseri bidashoboka, imiti yitwa arterial embolisation irashobora gukoreshwa kugirango igabanye ikibyimba. Hakozwe agace gato hanyuma catheter (tube tube) yinjizwa mumitsi nyamukuru yamaraso ijya mumpyiko. Uduce duto twa gelatine idasanzwe yatewe muri catheter mumitsi yamaraso. Sponges ibuza amaraso gutembera mumpyiko kandi ikabuza kanseri ya kanseri kubona ogisijeni nibindi bintu bakeneye gukura.

Muganga amaze gukuraho kanseri zose zishobora kugaragara mugihe cyo kubagwa, abarwayi bamwe bashobora guhabwa chimiotherapie cyangwa imiti ivura imirasire nyuma yo kubagwa kugirango bice selile zose zisigaye. Umuti watanzwe nyuma yo kubagwa, kugirango ugabanye ibyago ko kanseri izagaruka, byitwa kuvura indwara.

Imiti ivura imirasire

Imishwarara ivura ni imiti ikoresha kanseri ikoresha ingufu nyinshi za x-imirasire cyangwa ubundi bwoko bwimirasire yica kanseri cyangwa ikabuza gukura. Imiti ivura hanze ikoresha imashini hanze yumubiri kugirango yohereze imirasire yerekeza kumubiri hamwe na kanseri. Imiti ivura imirasire yo hanze ikoreshwa mu kuvura kanseri yimpyiko, kandi irashobora no gukoreshwa nkubuvuzi bwa palliative kugirango igabanye ibimenyetso kandi imibereho myiza.

Chimoterapi

Chimoterapi ni umuti wa kanseri ukoresha ibiyobyabwenge kugirango uhagarike imikurire ya kanseri, haba mu kwica selile cyangwa kubabuza gutandukana. Iyo chimiotherapie ifashwe numunwa cyangwa igaterwa mumitsi cyangwa imitsi, imiti yinjira mumaraso kandi irashobora kugera kanseri ya kanseri mumubiri (chimiotherapie sisitemu).

Reba Ibiyobyabwenge Byemewe Kanseri Yimpyiko (Akagari ka Renal) kubindi bisobanuro.

Immunotherapy

Immunotherapy nubuvuzi bukoresha sisitemu yumubiri yumurwayi kurwanya kanseri. Ibintu bikozwe numubiri cyangwa bikozwe muri laboratoire bikoreshwa mukuzamura, kuyobora, cyangwa kugarura umubiri kamere irinda kanseri. Ubu bwoko bwo kuvura kanseri nabwo bwitwa biotherapy cyangwa biologique therapy.

Ubwoko bukurikira bwa immunotherapie burimo gukoreshwa mu kuvura kanseri yimpyiko:

• Immune checkpoint inhibitor therapy: Ubwoko bumwebumwe bwingirangingo, nka selile T, hamwe na kanseri zimwe na zimwe zifite poroteyine zimwe na zimwe, bita proteine ​​proteyine, hejuru yabyo bikomeza kugenzura ubudahangarwa bw'umubiri. Iyo kanseri ya kanseri ifite proteine ​​nyinshi, ntabwo zizaterwa no kwicwa na selile T. Immune igenzura ibuza izo poroteyine kandi ubushobozi bwa selile T bwo kwica kanseri bwiyongera. Bakoreshwa mu kuvura abarwayi bamwe na bamwe bafite kanseri yimpyiko yateye imbere idashobora gukurwaho no kubagwa.

Hariho ubwoko bubiri bwubudahangarwa bwo kugenzura indwara:

• CTLA-4 inhibitor: CTLA-4 ni poroteyine hejuru ya selile T ifasha kugenzura ubudahangarwa bw'umubiri. Iyo CTLA-4 ifashe indi poroteyine yitwa B7 kuri selile ya kanseri, ibuza selile T kwica kanseri. Inzitizi za CTLA-4 zifatanije na CTLA-4 kandi zemerera selile T kwica kanseri. Ipilimumab ni ubwoko bwa CTLA-4 inhibitor.

Immune igenzura. Intungamubiri za poroteyine, nka B7-1 / B7-2 kuri selile zerekana antigen (APC) na CTLA-4 kuri selile T, zifasha kugenzura ubudahangarwa bw'umubiri. Iyo reseptor ya T-selile (TCR) ihuza na poroteyine za antigen hamwe ningenzi zikomeye za histocompatibilité (MHC) kuri APC na CD28 zihuza B7-1 / B7-2 kuri APC, selile T irashobora gukora. Ariko, guhuza B7-1 / B7-2 na CTLA-4 bituma selile T zidakora kuburyo zidashobora kwica selile yibibyimba mumubiri (panne ibumoso). Guhagarika guhuza B7-1 / B7-2 na CTLA-4 hamwe na inhibitor igenzura (antibody anti-CTLA-4) ituma selile T ikora kandi ikica selile yibibyimba (panel iburyo).

• PD-1 inhibitor: PD-1 ni poroteyine hejuru ya selile T ifasha kugenzura ubudahangarwa bw'umubiri. Iyo PD-1 ifatanye nindi poroteyine yitwa PDL-1 kuri selile ya kanseri, ihagarika selile T kwica kanseri. Inzitizi za PD-1 zifatanije na PDL-1 kandi zemerera selile T kwica selile. Nivolumab, pembrolizumab, na avelumab ni ubwoko bwa PD-1 inhibitor.

Immune igenzura. Intungamubiri za poroteyine, nka PD-L1 ku ngirabuzimafatizo na PD-1 kuri selile T, zifasha kugenzura ibisubizo by’ubudahangarwa. Guhambira PD-L1 na PD-1 bituma selile T itica selile yibibyimba mumubiri (panne ibumoso). Guhagarika guhuza PD-L1 na PD-1 hamwe na inhibitor igenzura (anti-PD-L1 cyangwa anti-PD-1) ituma selile T yica selile yibibyimba (panne iburyo).

• Interferon: Interferon igira uruhare mu igabana ry'uturemangingo twa kanseri kandi irashobora gutinda gukura kw'ibibyimba.

• Interleukin-2 (IL-2): IL-2 ituma imikurire n'ibikorwa bya selile nyinshi z'umubiri, cyane cyane lymphocytes (ubwoko bw'amaraso yera). Lymphocytes irashobora gutera no kwica selile.

Reba Ibiyobyabwenge Byemewe Kanseri Yimpyiko (Akagari ka Renal) kubindi bisobanuro.

Ubuvuzi bugamije

Ubuvuzi bugamije gukoresha imiti cyangwa ibindi bintu kugirango umenye kandi utere kanseri yihariye utiriwe wangiza selile zisanzwe. Ubuvuzi bugenewe hamwe na antiangiogenic ikoreshwa mu kuvura kanseri yimpyiko yateye imbere. Imiti igabanya ubukana ituma imiyoboro y'amaraso idakora mu kibyimba, bigatuma ikibyimba cyicwa n'inzara kandi kigahagarika gukura cyangwa kugabanuka.

Antibodiyite za monoclonal hamwe na kinase inhibitor ni ubwoko bubiri bwimiti igabanya ubukana bwa kanseri yimpyiko.

• Ubuvuzi bwa antibody ya Monoclonal bukoresha antibodies zakozwe muri laboratoire, uhereye mubwoko bumwe bwimikorere yumubiri. Iyi antibodies irashobora kumenya ibintu biri muri kanseri ya kanseri cyangwa ibintu bisanzwe bishobora gufasha kanseri gukura. Antibodiyite ifata ibintu kandi ikica selile ya kanseri, ikabuza gukura kwayo, cyangwa ikabuza gukwirakwira. Antibodiyite za Monoclonal zitangwa no gushiramo. Bashobora gukoreshwa bonyine cyangwa gutwara ibiyobyabwenge, uburozi, cyangwa ibikoresho bya radio bikoresha kanseri ya kanseri. Antibodiyite za monoclonal zikoreshwa mu kuvura kanseri yimpyiko zifata no guhagarika ibintu bitera imiyoboro mishya y'amaraso kwibibyimba. Bevacizumab ni antibody ya monoclonal.

• Inzitizi ya Kinase ihagarika ingirabuzimafatizo kandi zishobora kubuza gukura kw'imiyoboro mishya y'amaraso ibibyimba bigomba gukura.

Imikurire ya endoteliyale ikura (VEGF) inhibitor hamwe na mTOR inhibitor ni kinase inhibitor ikoreshwa mu kuvura kanseri yimpyiko.

• Inzitizi za VEGF: Utugingo ngengabuzima twa kanseri dukora ibintu bita VEGF, itera imiyoboro mishya y'amaraso gukora (angiogenez) kandi ifasha kanseri gukura. Inzitizi za VEGF zibuza VEGF no guhagarika imiyoboro mishya y'amaraso gukora. Ibi birashobora kwica selile kuko zikeneye imiyoboro mishya yamaraso kugirango ikure. Sunitinib, pazopanib, cabozantinib, axitinib, sorafenib, na lenvatinib ni inzitizi za VEGF.

• MTOR inhibitor: mTOR ni poroteyine ifasha selile kugabana no kubaho. mTOR ibuza guhagarika mTOR kandi irashobora gutuma selile ya kanseri idakura kandi ikarinda imikurire yimitsi mishya ikibyimba gikeneye gukura. Everolimus na temsirolimus ni mTOR inhibitor.

Reba Ibiyobyabwenge Byemewe Kanseri Yimpyiko (Akagari ka Renal) kubindi bisobanuro.

Ubwoko bushya bwo kuvura burimo kugeragezwa mubigeragezo byamavuriro.

Amakuru yerekeye ibizamini byamavuriro araboneka kurubuga rwa NCI.

Umuti wa kanseri yimpyiko urashobora gutera ingaruka.

Kumakuru yingaruka ziterwa no kuvura kanseri, reba urupapuro rwuruhande rwacu.

Abarwayi barashobora kwifuza gutekereza kubijyanye no kwipimisha kwa muganga.

Ku barwayi bamwe, kwitabira ikizamini cyamavuriro birashobora kuba uburyo bwiza bwo kuvura. Ibigeragezo bivura biri mubikorwa byubushakashatsi bwa kanseri. Igeragezwa rya Clinical rikorwa kugirango hamenyekane niba imiti mishya ya kanseri itekanye kandi ifite akamaro cyangwa nziza kuruta ubuvuzi busanzwe.

Benshi mubuvuzi busanzwe bwa kanseri bushingiye kubigeragezo byambere byubuvuzi. Abarwayi bitabiriye kwipimisha barashobora kuvurwa bisanzwe cyangwa kuba mubambere bahawe imiti mishya.

Abarwayi bitabira ibizamini byo kwa muganga nabo bafasha kunoza uburyo kanseri izavurwa mugihe kizaza. Nubwo ibigeragezo bivura bitaganisha ku buvuzi bushya, akenshi basubiza ibibazo byingenzi kandi bigafasha gutera imbere ubushakashatsi.

Abarwayi barashobora kwipimisha kwa muganga mbere, mugihe, cyangwa nyuma yo gutangira kuvura kanseri.

Igeragezwa rimwe na rimwe ririmo abarwayi bataravurwa. Ibindi bigeragezo bipima abarwayi bafite kanseri itameze neza. Hariho kandi ibizamini byo kwa muganga bipima uburyo bushya bwo guhagarika kanseri kongera kugaruka (kugaruka) cyangwa kugabanya ingaruka zo kuvura kanseri.

Igeragezwa rya Clinical ririmo kubera mu bice byinshi by'igihugu. Amakuru yerekeye ibizamini byamavuriro ashyigikiwe na NCI urashobora kubisanga kurubuga rwa NCI. Ibizamini bya Clinical bishyigikiwe nandi mashyirahamwe murashobora kubisanga kurubuga rwa ClinicalTrials.gov.

Ibizamini byo gukurikirana birashobora gukenerwa.

Bimwe mubizamini byakozwe mugupima kanseri cyangwa kumenya icyiciro cya kanseri birashobora gusubirwamo. Ibizamini bimwe bizasubirwamo kugirango harebwe uburyo ubuvuzi bukora neza. Ibyemezo bijyanye no gukomeza, guhindura, cyangwa guhagarika ubuvuzi birashobora gushingira kubisubizo byibi bizamini.

Bimwe mubizamini bizakomeza gukorwa buri gihe nyuma yubuvuzi burangiye. Ibisubizo by'ibi bizamini birashobora kwerekana niba ubuzima bwawe bwarahindutse cyangwa niba kanseri yarongeye (garuka). Ibi bizamini rimwe na rimwe byitwa gukurikirana-ibizamini cyangwa kugenzura.

Kuvura Icyiciro cya I Kanseri Yimpyiko

Kumakuru yerekeye imiti yavuzwe hepfo, reba igice cyo kuvura.

Kuvura icyiciro cya mbere kanseri yimpyiko zishobora kubamo ibi bikurikira:

• Kubaga (nephrectomy radical, nephrectomy yoroshye, cyangwa nephrectomy igice).

• Imishwarara yimiti nkubuvuzi bwa palliative kugirango igabanye ibimenyetso kubarwayi badashobora kubagwa.

• Embolisation ya Arterial nkubuvuzi bwa palliative.

• Ikigeragezo cyamavuriro yubuvuzi bushya.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Kuvura Icyiciro cya II Kanseri Yimpyiko

Kumakuru yerekeye imiti yavuzwe hepfo, reba igice cyo kuvura.

Kuvura kanseri yo mu cyiciro cya II bishobora kuba bikubiyemo ibi bikurikira:

• Kubaga (nephrectomy radical cyangwa nephrectomy igice).

• Kubaga (nephrectomy), mbere cyangwa nyuma yo kuvura imirasire.

• Imishwarara yimiti nkubuvuzi bwa palliative kugirango igabanye ibimenyetso kubarwayi badashobora kubagwa.

• Embolisation ya Arterial nkubuvuzi bwa palliative.

• Ikigeragezo cyamavuriro yubuvuzi bushya.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Kuvura Icyiciro cya III Kanseri Yimpyiko

Kumakuru yerekeye imiti yavuzwe hepfo, reba igice cyo kuvura.

Kuvura kanseri yo mu cyiciro cya III bishobora kuba bikubiyemo ibi bikurikira:

• Kubaga (nephrectomy radical). Imiyoboro y'amaraso y'impyiko hamwe na lymph node nayo irashobora gukurwaho.

• Embolisation ya Arterial ikurikirwa no kubagwa (nephrectomy radical).

• Imiti ivura imishwarara nka palliative therapy kugirango igabanye ibimenyetso kandi izamure ubuzima.

• Embolisation ya Arterial nkubuvuzi bwa palliative.

• Kubaga (nephrectomy) nk'ubuvuzi bwa palliative.

• Ubuvuzi bwimirasire mbere cyangwa nyuma yo kubagwa (nephrectomy radical).

• Igeragezwa rya clinique yubuvuzi bwa biologiya nyuma yo kubagwa.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Kuvura Icyiciro cya IV na Kanseri Yimpyiko Yisubiramo

Kumakuru yerekeye imiti yavuzwe hepfo, reba igice cyo kuvura.

Kuvura icyiciro cya IV na kanseri yimpyiko zisubiramo bishobora kuba bikubiyemo ibi bikurikira:

• Kubaga (nephrectomy radical).

• Kubaga (nephrectomy) kugirango ugabanye ubunini bwikibyimba.

• Ubuvuzi bugamije hamwe numwe cyangwa benshi muribi bikurikira: sorafenib, sunitinib, temsirolimus, pazopanib, everolimus, bevacizumab, axitinib, cabozantinib, cyangwa lenvatinib.

• Immunotherapy hamwe numwe cyangwa benshi muribi bikurikira: interferon, interleukin-2, nivolumab, ipilimumab, pembrolizumab, cyangwa avelumab.

• Imiti ivura imishwarara nka palliative therapy kugirango igabanye ibimenyetso kandi izamure ubuzima.

Koresha ubushakashatsi bwamavuriro kugirango ushakishe NCI ifashwa na kanseri ivura abarwayi. Urashobora gushakisha ibigeragezo ukurikije ubwoko bwa kanseri, imyaka yumurwayi, n’aho ibizamini bikorerwa. Amakuru rusange yerekeye ibizamini byamavuriro nayo arahari.

Kumenya Byinshi Kanseri Yimpyiko

Ushaka amakuru menshi yikigo cyigihugu cya kanseri kubyerekeye kanseri yimpyiko, reba ibi bikurikira:

• Kanseri y'impyiko Urupapuro

• Ibiyobyabwenge Byemewe Kanseri y'impyiko

• Immunotherapy yo kuvura Kanseri

• Intego zo kuvura Kanseri

• Angiogenezi Inhibitor

• Kwipimisha genetike ya Syndromes Yarazwe Kanseri

• Itabi (rikubiyemo ubufasha mu kureka)

Kumakuru rusange ya kanseri nibindi bikoresho biva mu kigo cyigihugu cya kanseri, reba ibi bikurikira:

• Ibyerekeye Kanseri

• Gutegura

• Chimiotherapie nawe: Inkunga kubantu barwaye Kanseri

• Ubuvuzi bwimirasire nawe: Inkunga kubantu barwaye Kanseri

• Guhangana na Kanseri

• Ibibazo byo Kubaza Muganga wawe kuri Kanseri

• Abacitse ku icumu n'abarezi

Gutondekanya itariki Gutondekanya amanota

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