Mitundu / midline / wodwala-mwana-midline-tract-carcinoma-treatment-pdq

Childhood Midline Tract Carcinoma yokhala ndi NUT Gene Changes Treatment (®) -Patient Version

Zambiri Zokhudza Ubwana Midline Tract Carcinoma

MFUNDO ZOFUNIKA

• Childhood midline tract carcinoma ndi matenda omwe ma cell oyipa (khansa) amapangika munjira yopumira kapena malo ena pakati pa thupi.

• Midline tract carcinoma nthawi zina imayamba chifukwa cha kusintha kwa mtundu wa NUT.

• Zizindikiro za matenda apakati a carcinoma sizofanana mwana aliyense.

• Kuyesa komwe kumayesa thupi kumagwiritsidwa ntchito kuthandizira (kupeza) ndikuzindikira midline tract carcinoma.

• Midline tract carcinoma imakula ndikufalikira mwachangu.

Childhood midline tract carcinoma ndi matenda omwe ma cell oyipa (khansa) amapangika munjira yopumira kapena malo ena pakati pa thupi.

Thirakiti limapangidwa ndi mphuno, khosi, kholingo, trachea, bronchi, ndi mapapo. Midline tract carcinoma amathanso kupanga m'malo ena pakati pa thupi, monga thymus, dera pakati pa mapapo, kapamba, chiwindi, ndi chikhodzodzo.

Midline tract carcinoma nthawi zina imayamba chifukwa cha kusintha kwa mtundu wa NUT.

Midline tract carcinoma imayamba chifukwa cha kusintha kwa chromosome. Selo lililonse m'thupi limakhala ndi DNA (majini omwe amasungidwa mkati mwa ma chromosomes) omwe amayang'anira momwe khungu limawonekera komanso momwe limagwirira ntchito. Midline tract carcinoma imatha kupangidwa pomwe gawo la DNA yochokera ku chromosome 15 (yotchedwa NUT gene) imalumikizana ndi DNA kuchokera ku chromosome ina.

Zizindikiro za matenda apakati a carcinoma sizofanana mwana aliyense.

Zizindikiro za midline tract carcinoma zimadalira komwe khansa idapangika mthupi.

Kuyesa komwe kumayesa thupi kumagwiritsidwa ntchito kuthandizira (kupeza) ndikuzindikira midline tract carcinoma.

Mayeso omwe amagwiritsidwa ntchito kuti azindikire komanso kupeza matenda apakati a carcinoma amadalira komwe khansara idapangidwa mthupi ndipo imatha kukhala ndi izi:

• Kuyezetsa thupi komanso mbiri yaumoyo: Kuyesedwa kwa thupi kuti muwone zizindikiritso zaumoyo, kuphatikizapo kuyang'ana ngati pali matenda, monga zotupa kapena china chilichonse chomwe chikuwoneka chachilendo. Mbiri yokhudzana ndi thanzi la wodwalayo komanso matenda am'mbuyomu komanso chithandizo chamankhwala adzachitidwanso.

• X-ray pachifuwa : X-ray pachifuwa. X-ray ndi mtundu wa mphamvu yamphamvu yomwe imatha kupyola thupi ndikupita mufilimu, ndikupanga chithunzi cha madera omwe ali mthupi.

• MRI (magnetic resonance imaging): Njira yomwe imagwiritsa ntchito maginito, mafunde a wailesi, komanso kompyuta kuti ipange zithunzi zingapo za malo amthupi, monga mutu ndi khosi. Njirayi imatchedwanso nuclear magnetic resonance imaging (NMRI).

• CT scan (CAT scan): Njira yomwe imapanga zithunzi zingapo zamatupi amthupi zomwe zidatengedwa mbali zosiyanasiyana. Zithunzizo zimapangidwa ndi kompyuta yolumikizidwa ndi makina a x-ray. Utoto ukhoza kulowetsedwa mumtsempha kapena kumeza kuti ziwalo kapena ziwalo ziwoneke bwino. Njirayi imatchedwanso computed tomography, kompyuta tomography, kapena kompyuta axial tomography.

Kujambula kwa tomography (CT) pamutu ndi khosi. Mwanayo wagona patebulo lomwe limadutsa pa CT scanner, lomwe limatenga zithunzi za x-ray zamkati mwa mutu ndi khosi.

• Biopsy: Kuchotsa kwa ma cell kuti athe kuwonedwa ndi microscope ndi wodwala kuti adziwe ngati ali ndi khansa.

Mayeso otsatirawa atha kuchitidwa pamitundu yama cell yomwe idachotsedwa:

• Immunohistochemistry: Kuyesa kwa labotale komwe kumagwiritsa ntchito ma antibodies kuti aone ngati ali ndi ma antigen (zolembera) muzitsanzo za minofu ya wodwala. Ma antibodies nthawi zambiri amalumikizidwa ndi enzyme kapena utoto wa fulorosenti. Ma antibodies atagwirizana ndi antigen inayake munthawi ya minofu, enzyme kapena utoto umayambitsidwa, ndipo antigen imatha kuwonedwa ndi microscope. Mayeso amtunduwu amagwiritsidwa ntchito pothandiza kuzindikira khansa ndikuthandizira kudziwa khansa yamtundu wina wa khansa.

• Kusanthula kwa cytogenetic: Kuyesa kwa labotale komwe ma chromosomes am'magazi am'mafupa, magazi, chotupa, kapena minofu ina amawerengedwa ndikuwunika ngati pali kusintha kulikonse, monga kusweka, kusowa, kukonzedwanso, kapena ma chromosomes owonjezera. Kusintha kwa ma chromosomes ena kungakhale chizindikiro cha khansa. Kusanthula kwa cytogenetic kumagwiritsidwa ntchito kuthandizira kuzindikira khansa, kukonzekera chithandizo, kapena kudziwa momwe chithandizo chikuyendera. Mayesero ena, monga fluorescence in situ hybridization (FISH), amathanso kuchitidwa kuti asinthe kusintha kwina kwama chromosomes.

Midline tract carcinoma imakula ndikufalikira mwachangu.

Khansara yapakatikati yamagulu osinthika amtundu wa NUT ndi khansa yaukali yomwe singachiritsidwe.

Magawo a Ubwana Midline Tract Carcinoma

Njira yomwe amagwiritsidwa ntchito pofufuza ngati khansa yafalikira kuchokera pomwe idayambira kumadera oyandikira kapena mbali zina za thupi imatchedwa staging. Palibe njira yokhazikika yokhazikitsira carcinoma yapakati paubwana wapakati. Zotsatira za mayeso ndi njira zomwe zachitika kuti azindikire midline tract carcinoma amagwiritsidwa ntchito kuthandizira kupanga zisankho zamankhwala.

Matenda aang'ono pakati pa ana a carcinoma amatha kufalikira kumatenda am'mimba, olumikizana mozungulira mapapo, mafupa, kapena mafupa.

Chithandizo Chosankha Mwachidule

MFUNDO ZOFUNIKA

• Pali mitundu yosiyanasiyana ya chithandizo cha ana omwe ali ndi midline tract carcinoma.

• Ana omwe ali ndi midline tract carcinoma ayenera kukonzekera kukonzekera ndi gulu la madokotala omwe ndi akatswiri othandiza khansa yaubwana.

• Mitundu itatu yamankhwala imagwiritsidwa ntchito:

• Opaleshoni

• Thandizo la radiation

• Chemotherapy

• Mitundu yatsopano yamankhwala ikuyesedwa m'mayesero azachipatala.

• Chithandizo chofuna

• Chithandizo cha ubwana wapakati pa carcinoma chitha kuyambitsa mavuto.

• Odwala angaganize zopita nawo kukayezetsa.

• Odwala amatha kulowa m'mayesero azachipatala asanayambe, asanayambe, kapena atayamba kulandira chithandizo cha khansa.

• Mayeso otsatirawa angafunike.

Pali mitundu yosiyanasiyana ya chithandizo cha ana omwe ali ndi midline tract carcinoma.

Mankhwala ena ndi ofanana (mankhwala omwe akugwiritsidwa ntchito pano), ndipo ena akuyesedwa m'mayesero azachipatala. Kuyesedwa kwachipatala ndi kafukufuku wofufuza wothandizira kusintha chithandizo chamakono kapena kupeza zidziwitso zamankhwala atsopano kwa odwala khansa. Pamene mayesero azachipatala awonetsa kuti chithandizo chatsopano ndichabwino kuposa chithandizo chamankhwala, chithandizocho chitha kukhala chamankhwala wamba.

Chifukwa khansa mwa ana ndiyosowa, kutenga nawo mbali pakuyesa kwachipatala kuyenera kuganiziridwa. Mayesero ena azachipatala ndi otseguka kwa odwala omwe sanayambe kulandira chithandizo.

Ana omwe ali ndi midline tract carcinoma ayenera kukonzekera kukonzekera ndi gulu la madokotala omwe ndi akatswiri othandiza khansa yaubwana.

Chithandizo chidzayang'aniridwa ndi oncologist wa ana, dokotala yemwe amadziwika bwino pochiza ana omwe ali ndi khansa. Katswiri wa oncologist amagwira ana ndi akatswiri ena azaumoyo a ana omwe ndi akatswiri pochiza ana omwe ali ndi khansa komanso omwe amadziwika bwino pamankhwala ena. Izi zingaphatikizepo akatswiri awa ndi ena:

• Dokotala wa ana.

• Dokotala wa ana.

• Wofufuza oncologist.

• Wodwala.

• Katswiri wa namwino wa ana.

• Wogwira ntchito.

• Katswiri wokonzanso.

• Katswiri wa zamaganizo.

• Katswiri wa moyo wa ana.

Mitundu itatu yamankhwala imagwiritsidwa ntchito:

Opaleshoni

Kuchita opaleshoni kuchotsa chotupacho ndi imodzi mwazithandizo zazikulu zomwe zimagwiritsidwa ntchito paubwana wapakatikati wa carcinoma.

Thandizo la radiation

Thandizo la radiation ndi chithandizo cha khansa chomwe chimagwiritsa ntchito ma x-ray amphamvu kapena mitundu ina ya radiation kuti iphe ma cell a khansa kapena kuti asakule. Mankhwala ochiritsira akunja amagwiritsa ntchito makina kunja kwa thupi kuti atumize cheza chaku khansa.

Chemotherapy

Chemotherapy ndi mankhwala a khansa omwe amagwiritsa ntchito mankhwala oletsa kukula kwa maselo a khansa, mwina popha ma cell kapena kuwaletsa kuti asagawane. Chemotherapy ikamamwa pakamwa kapena kulowetsedwa mumtsempha kapena minofu, mankhwalawa amalowa m'magazi ndipo amatha kufikira ma cell a khansa mthupi lonse (systemic chemotherapy).

Mitundu yatsopano yamankhwala ikuyesedwa m'mayesero azachipatala.

Gawo lachiduleli likufotokoza zamankhwala omwe akuwerengedwa m'mayesero azachipatala. Sizingatchule chithandizo chilichonse chatsopano chomwe akuphunzira. Zambiri zamayeso azachipatala zimapezeka patsamba la NCI.

Chithandizo chofuna

Chithandizo choyenera ndi chithandizo chomwe chimagwiritsa ntchito mankhwala osokoneza bongo kapena zinthu zina kuzindikira ndi kuwononga maselo ena a khansa pomwe sizivulaza maselo abwinobwino. Mankhwala atsopano omwe amaletsa ma cell a khansa kukula akuwerengedwa kuti athetse midline tract carcinoma.

Chithandizo cha ubwana wapakati pa carcinoma chitha kuyambitsa mavuto.

Kuti mumve zambiri zamankhwala oyambilira omwe amayamba mukalandira chithandizo cha khansa, onani tsamba lathu la Zotsatira Zotsatira.

Odwala angaganize zopita nawo kukayezetsa.

Kwa odwala ena, kutenga nawo mbali pakuyesa chithandizo chachipatala kungakhale njira yabwino kwambiri yothandizira. Mayesero azachipatala ndi gawo limodzi la kafukufuku wa khansa. Mayesero azachipatala amachitika kuti apeze ngati mankhwala atsopano a khansa ndi otetezeka komanso ogwira ntchito kapena abwinoko kuposa mankhwala wamba.

Njira zambiri zamankhwala zochiritsira khansa zimachokera kumayeso am'mbuyomu azachipatala. Odwala omwe amatenga nawo mbali pachipatala atha kulandira chithandizo chofananira kapena kukhala oyamba kulandira chithandizo chatsopano.

Odwala omwe amatenga nawo mbali pazoyeserera zamankhwala amathandizanso kukonza momwe khansa idzathandizire mtsogolo. Ngakhale mayesero azachipatala satsogolera kuchipatala chatsopano, nthawi zambiri amayankha mafunso ofunikira ndikuthandizira kupititsa patsogolo kafukufuku.

Odwala amatha kulowa m'mayesero azachipatala asanayambe, asanayambe, kapena atayamba kulandira chithandizo cha khansa.

Mayesero ena azachipatala amangophatikizapo odwala omwe sanalandire chithandizo. Mayesero ena amayesa chithandizo kwa odwala omwe khansa yawo sinakhale bwino. Palinso mayesero azachipatala omwe amayesa njira zatsopano zothetsera khansa kuti isabwererenso (kubwerera) kapena kuchepetsa zovuta zoyambitsidwa ndi khansa.

Mayesero azachipatala akuchitika m'malo ambiri mdziko muno. Zambiri zamayeso azachipatala othandizidwa ndi NCI zitha kupezeka patsamba lofufuza zamankhwala la NCI. Mayesero azachipatala othandizidwa ndi mabungwe ena amapezeka patsamba la ClinicalTrials.gov.

Mayeso otsatirawa angafunike.

Ena mwa mayesero omwe adachitika kuti apeze khansa kapena kuti adziwe momwe khansa iliri angabwerezedwenso. Mayesero ena adzabwerezedwa kuti awone momwe mankhwalawa akugwirira ntchito. Zisankho zakuti mupitilize, kusintha, kapena kusiya kulandira chithandizo zitha kutengera zotsatira za mayeso awa.

Kuyesaku kumangopitilira kuchitika nthawi ndi nthawi mankhwala atatha. Zotsatira zamayesowa zitha kuwonetsa ngati matenda a mwana wanu asintha kapena ngati khansa yabwereranso (kubwerera). Mayesowa nthawi zina amatchedwa kuyesa kutsata kapena kukayezetsa.

Kuchiza kwa Midline Tract Carcinoma Yatsopano Yodziwika Kwambiri ya Ana

Kuti mumve zambiri zamankhwala omwe atchulidwa pansipa, onani gawo la Chisankho Chachidule.

Palibe chithandizo chamankhwala cha khansa yaposachedwa ya midline yomwe imapezeka ndi kusintha kwa majini a NUT. Chithandizo chingaphatikizepo izi:

• Opaleshoni kuchotsa chotupacho.

• Thandizo la radiation lakunja.

• Chemotherapy.

• Kuyesedwa kwachipatala kwa mankhwala osokoneza bongo atsopano.

Gwiritsani ntchito kusaka kwathu kwamankhwala kuti mupeze mayesero azachipatala omwe amathandizidwa ndi NCI omwe akulandira odwala. Mutha kusaka mayesero kutengera mtundu wa khansa, zaka za wodwalayo, komanso komwe mayeserowo akuchitika. Zambiri pazokhudza mayesero azachipatala zimapezekanso.

Chithandizo cha Recurrent Childhood Midline Tract Carcinoma

Kuti mumve zambiri zamankhwala omwe atchulidwa pansipa, onani gawo la Chisankho Chachidule.

Chithandizo cha khansa yapakatikati yapakatikati yapakatikati ndi kusintha kwa majini a NUT kungaphatikizepo izi:

• Kuyesedwa kwachipatala komwe kumayang'ana chotupa cha wodwalayo ngati majini ena asintha. Mtundu wa mankhwala omwe akulimbikitsidwa omwe adzapatsidwe kwa wodwala umadalira mtundu wa kusintha kwa majini.

Gwiritsani ntchito kusaka kwathu kwamankhwala kuti mupeze mayesero azachipatala omwe amathandizidwa ndi NCI omwe akulandira odwala. Mutha kusaka mayesero kutengera mtundu wa khansa, zaka za wodwalayo, komanso komwe mayeserowo akuchitika. Zambiri pazokhudza mayesero azachipatala zimapezekanso.

Kuti mudziwe Zambiri Zokhudza Ubwana Midline Tract Carcinoma

Kuti mumve zambiri kuchokera ku National Cancer Institute yokhudza midline tract carcinoma, onani izi:

• Tsamba Loyambira Khansa Yam'mutu Ndi Khosi

• Computed Tomography (CT) Zithunzi ndi Khansa

Kuti mumve zambiri za khansa yaubwana ndi zina zothandiza za khansa, onani izi:

• Za Khansa

• Khansa Za Ana

• Cure Search for Cancer ya Ana Tulukani Chodzikanira

• Zotsatira Zochedwetsa Khansa Yaana

• Achinyamata ndi Achinyamata Achikulire ndi Khansa

• Ana omwe ali ndi khansa: Upangiri wa Makolo

• Khansa mwa Ana ndi Achinyamata

• Kusinthana

• Kulimbana ndi khansa

• Mafunso oti mufunse dokotala wanu za khansa

• Kwa Opulumuka ndi Owasamalira

Za Chidule cha

Za

Physician Data Query () ndi nkhokwe ya National Cancer Institute's (NCI's) yokhudza zambiri za khansa. Database ya ili ndi chidule cha zomwe zatulutsidwa posachedwa popewa khansa, kuzindikira, ma genetics, chithandizo, chisamaliro chothandizira, komanso mankhwala othandizira komanso othandizira. Zambiri mwachidule zimabwera m'mitundu iwiri. Omasulira akatswiriwa ali ndi zambiri zolembedwa mchilankhulo chaukadaulo. Mitundu ya odwala imalembedwa m'njira yosavuta kumva, yopanda ukadaulo. Mabaibulo onsewa ali ndi chidziwitso cha khansa chomwe ndicholondola komanso chaposachedwa ndipo matembenuzidwe ambiri amapezekanso m'Chisipanishi.

ndi ntchito ya NCI. NCI ndi gawo la National Institutes of Health (NIH). NIH ndiye likulu la kafukufuku waboma. Zidule za zimakhazikitsidwa pakuwunika kodziyimira pawokha zolemba zamankhwala. Sindiwo malingaliro a NCI kapena NIH.

Cholinga cha Chidule ichi

Chidule cha chidziwitso cha khansa ya chili ndi zambiri pakadali pano zamankhwala am'mimba apakati pa carcinoma. Zimatanthauza kudziwitsa ndi kuthandiza odwala, mabanja, ndi osamalira. Sichipereka malangizo kapena malingaliro apadera popanga zisankho pazokhudzaumoyo.

Owunikanso ndi Zosintha

Mamembala Olemba amalemba zidule za khansa ya ndikuziwongolera. Ma board awa amapangidwa ndi akatswiri azithandizo zamatenda a khansa ndi zina zapadera zokhudzana ndi khansa. Zowombazi zimawunikiridwa pafupipafupi ndipo amasintha pakakhala zatsopano. Deti pachidule chilichonse ("Kusinthidwa") ndi tsiku losintha posachedwa kwambiri.

Zomwe zili pachidule ichi zidatengedwa kuchokera ku mtundu wa akatswiri azaumoyo, womwe umawunikidwa pafupipafupi ndikusinthidwa momwe ungafunikire, ndi Pediatric Treatment Editorial Board.

Zambiri Zoyesa Zachipatala

Kuyesedwa kwachipatala ndi kafukufuku woti ayankhe funso lasayansi, monga ngati mankhwala amodzi aposa ena. Mayesero amatengera maphunziro am'mbuyomu ndi zomwe taphunzira mu labotale. Chiyeso chilichonse chimayankha mafunso ena asayansi kuti apeze njira zatsopano komanso zabwino zothandiza odwala khansa. Mukamayesedwa azachipatala, zambiri zimasonkhanitsidwa pazokhudza chithandizo chatsopano ndi momwe chimagwirira ntchito. Ngati kuyesa kwachipatala kukuwonetsa kuti chithandizo chatsopano ndichabwino kuposa chomwe chikugwiritsidwa ntchito pano, chithandizo chatsopano chitha kukhala "chovomerezeka". Odwala angaganize zopita nawo kukayezetsa. Mayesero ena azachipatala ndi otseguka kwa odwala omwe sanayambe kulandira chithandizo.

Mayesero azachipatala amapezeka pa intaneti patsamba la NCI. Kuti mumve zambiri, imbani Cancer Information Service (CIS), malo olumikizirana ndi NCI, ku 1-800-4-CANCER (1-800-422-6237).

Chilolezo Chogwiritsa Ntchito Chidule Ichi

ndi dzina lolembedwa. Zomwe zili mu zikalata za zitha kugwiritsidwa ntchito momasuka ngati zolemba. Sizingadziwike kuti ndi chidule cha khansa ya NCI pokhapokha chidule chonse chikuwonetsedwa ndikusinthidwa pafupipafupi. Komabe, wogwiritsa akhoza kuloledwa kulemba chiganizo monga "Chidule cha chidziwitso cha khansa ya PDI ya NCI chokhudza kupewa khansa ya m'mawere chimanena zoopsa zake motere: [onaninso mwachidule mwachidule]."

Njira yabwino yolongosola chidule cha ndi:

Zithunzi pazidulezi zimagwiritsidwa ntchito ndi chilolezo cha wolemba, wojambula, ndi / kapena wofalitsa kuti azigwiritsidwa ntchito pazidule za zokha. Ngati mukufuna kugwiritsa ntchito chithunzi kuchokera pachidule cha ndipo simukugwiritsa ntchito chidule chonse, muyenera kupeza chilolezo kuchokera kwa mwininyumba. Sizingaperekedwe ndi National Cancer Institute. Zambiri zogwiritsa ntchito zithunzizi mwachidule, komanso zithunzi zina zambiri zokhudzana ndi khansa zitha kupezeka mu Visuals Online. Zowoneka paintaneti ndi zithunzi zoposa 3,000 zasayansi.

Chodzikanira

Zomwe zidafotokozedwazi siziyenera kugwiritsidwa ntchito popanga chisankho chobwezera inshuwaransi. Zambiri pazokhudza inshuwaransi zikupezeka ku Cancer.gov patsamba la Managing Care Care.

Lumikizanani nafe

Zambiri zokhudzana ndi kulumikizana nafe kapena kulandira thandizo patsamba la Cancer.gov zitha kupezeka patsamba Lumikizanani nafe kuti tithandizidwe. Mafunso amathanso kuperekedwa ku Cancer.gov kudzera pa Tsamba Lakutumiza la Imelo.

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