Txog-mob cancer / kho mob / kuaj mob-sim / mob / uterine-sarcoma / kev kho mob
Kev Kho Mob Tshuaj Kuaj Rau Kev Kho Mob Uterine Sarcoma
Cov chaw kuaj mob yog cov kev tshawb fawb tshawb fawb uas cuam tshuam nrog tib neeg. Kev kuaj mob hauv cov npe no yog rau kev kho tus mob sarcoma. Txhua qhov kev sim ntawm daim npe tau txhawb los ntawm NCI.
NCI cov ncauj lus tseem ceeb txog kev sim kho mob piav qhia txog ntau hom thiab ncua sij hawm ntawm kev sim thiab seb lawv raug coj los ua li cas. Cov chaw soj ntsuam kuaj xyuas txoj hauv kev tshiab los tiv thaiv, kuaj pom, lossis kho kab mob. Tej zaum koj yuav xav xav txog kev koom tes hauv kev sim tshuaj kuaj mob. Tham nrog koj tus kws kho mob kom pab txiav txim siab yog tias ib qho zoo rau koj.
Kev Hais Plaub 1-5 ntawm 5
Nivolumab hauv Kev Kho Cov Neeg Mob Nrog Metastatic lossis Mob Khees Xaws Uterine Cancer
Kev sim qib II no kawm txog seb nivolumab ua haujlwm zoo npaum li cas rau kev kho cov neeg mob qog nqaij hlav hauv tsev menyuam uas tau kis mus rau lwm qhov chaw hauv lub cev (metastatic) lossis rov qab los tom qab lub sijhawm txhim kho (rov muaj dua). Kev txhaj tshuaj tiv thaiv kab mob nrog monoclonal tiv thaiv kab mob, xws li nivolumab, tuaj yeem pab lub cev tiv thaiv kab mob hauv lub cev tua cov kabmob, thiab yuav cuam tshuam lub peev xwm ntawm cov qog ntshav kom loj hlob thiab kis tau.
Qhov chaw: 7 thaj chaw
Luv Ntsej Muag Vaginal Cuff Brachytherapy Hauv Kev Kho Tus Neeg Mob Mob Qog I-II Qog Kab Mob Qog Pob Qog
No randomized theem III kev sim kawm luv luv mob chaw mos cuff brachytherapy pom zoo npaum li cas nws ua haujlwm piv nrog cov txheej txheem kev saib xyuas chaw mos cuff brachytherapy hauv kev kho cov neeg mob theem I-II endometrial cancer. Luv luv ntawm qhov paum brachytherapy, kuj hu ua kev kho hluav taws xob sab hauv, siv (dhau sijhawm luv luv) cov khoom siv xov tooj cua tso ncaj qha mus rau lossis ze ze ntawm cov qog ntawm qhov chaw mos ua kom tua cov qog.
Qhov chaw: 7 thaj chaw
Kev Tshawb Xyuas sai thiab Kev Ntsuam Xyuas Cov Lus Teb ntawm Cov Txheej Txheem Tiv Thaiv Neoplastic hauv Pob Qog Tsis Txhaum (RARE CANCER) Kev Sim: RARE 1 Nilotinib thiab Paclitaxel
Keeb kwm yav dhau los: Cov neeg muaj mob qog nqaij hlav feem ntau muaj kev xaiv kho tsawg. Lub biology ntawm cov qog nqaij hlav tsis tshua muaj kev nkag siab zoo. Cov kws tshawb nrhiav xav nrhiav txoj kev kho zoo dua rau cov qog nqaij hlav no. Lawv xav kuaj 2 cov tshuaj uas, noj ib qho, tau pab cov neeg uas tsis mob qog nqaij hlav tsis tshua muaj mob. Lawv xav pom tias cov tshuaj ua ke no tuaj yeem ua rau mob qog nqaij hlav tsawg lossis tso tseg tsis txhob loj hlob. Lub Hom Phiaj: Xav paub yog nilotinib thiab paclitaxel yuav muaj txiaj ntsig zoo rau cov neeg muaj mob qog nqaij hlav tsawg. Kev Muaj Cai Tau Txais: Cov neeg muaj hnub nyoog 18 xyoo thiab laus dua uas muaj mob tsawg, mob cancer uas tau nce siab tom qab tau txais kev kho mob tus qauv, lossis qhov uas tsis muaj kev kho kom zoo. Tsim: Cov neeg koom yuav raug tshuaj ntsuam xyuas keeb kwm kev mob thiab kuaj lub cev. Lawv yuav muaj kev kuaj ntshav thiab kuaj zis. Lawv yuav muaj kev kuaj cev xeeb tub yog tias xav tau. Lawv yuav muaj cov electrocardiogram los kuaj xyuas lawv lub plawv. Lawv yuav muaj duab ntxaij mus ntsuas lawv cov qog. Cov neeg koom yuav rov ua cov ntawv ntsuam xyuas thaum qhov kev kawm. Cov neeg tuaj koom yuav tau txais nilotinib thiab paclitaxel. Cov tshuaj tau muab rau hauv 28-hnub mus ncig. Nilotinib yog tshuaj ntsiav uas noj qhov ncauj ob zaug ib hnub. Paclitaxel yuav muab rau cov leeg nruab nrog kab lossis nruab nrab kab ib zaug ib lub lim tiam rau thawj 3 lub lim tiam ntawm txhua lub voj voog. Cov neeg koom yuav khaws cov ntawv sau cia tshuaj. Lawv yuav taug qab thaum lawv noj tshuaj kawm thiab kev phiv uas lawv muaj. Cov neeg koom yuav tuaj yeem kuaj pob qog noj tawm los tau. Cov neeg tuaj koom tuaj yeem koom nrog txoj kev tshawb no kom txog thaum lawv cov kab mob phem dua lossis lawv muaj kev phiv tshuaj tsis zoo. Cov neeg tuaj koom yuav tau hu xov tooj rov qab txog 30 hnub tom qab noj cov tshuaj kawg ntawm cov tshuaj kawm. Cov neeg tuaj koom yuav tau txais nilotinib thiab paclitaxel. Cov tshuaj tau muab rau hauv 28-hnub mus ncig. Nilotinib yog tshuaj ntsiav uas noj qhov ncauj ob zaug ib hnub. Paclitaxel yuav muab rau cov leeg nruab nrog kab lossis nruab nrab kab ib zaug ib lub lim tiam rau thawj 3 lub lim tiam ntawm txhua lub voj voog. Cov neeg koom yuav khaws cov ntawv sau cia tshuaj. Lawv yuav taug qab thaum lawv noj tshuaj kawm thiab kev phiv uas lawv muaj. Cov neeg koom yuav tuaj yeem kuaj pob qog noj tawm los tau. Cov neeg tuaj koom tuaj yeem koom nrog txoj kev tshawb no kom txog thaum lawv cov kab mob phem dua lossis lawv muaj kev phiv tshuaj tsis zoo. Cov neeg tuaj koom yuav tau hu xov tooj rov qab txog 30 hnub tom qab noj cov tshuaj kawg ntawm cov tshuaj kawm. Cov neeg tuaj koom yuav tau txais nilotinib thiab paclitaxel. Cov tshuaj tau muab rau hauv 28-hnub mus ncig. Nilotinib yog tshuaj ntsiav uas noj qhov ncauj ob zaug ib hnub. Paclitaxel yuav muab rau cov leeg nruab nrog kab lossis nruab nrab kab ib zaug ib lub lim tiam rau thawj 3 lub lim tiam ntawm txhua lub voj voog. Cov neeg koom yuav khaws cov ntawv sau cia tshuaj. Lawv yuav taug qab thaum lawv noj tshuaj kawm thiab kev phiv uas lawv muaj. Cov neeg koom yuav tuaj yeem kuaj pob qog noj tawm los tau. Cov neeg tuaj koom tuaj yeem koom nrog txoj kev tshawb no kom txog thaum lawv cov kab mob phem dua lossis lawv muaj kev phiv tshuaj tsis zoo. Cov neeg tuaj koom yuav tau hu xov tooj rov qab txog 30 hnub tom qab noj cov tshuaj kawg ntawm cov tshuaj kawm. Paclitaxel yuav muab rau cov leeg nruab nrog kab lossis nruab nrab kab ib zaug ib lub lim tiam rau thawj 3 lub lim tiam ntawm txhua lub voj voog. Cov neeg koom yuav khaws cov ntawv sau cia tshuaj. Lawv yuav taug qab thaum lawv noj tshuaj kawm thiab kev phiv uas lawv muaj. Cov neeg koom yuav tuaj yeem kuaj pob qog noj tawm los tau. Cov neeg tuaj koom tuaj yeem koom nrog txoj kev tshawb no kom txog thaum lawv cov kab mob phem dua lossis lawv muaj kev phiv tshuaj tsis zoo. Cov neeg tuaj koom yuav tau hu xov tooj rov qab txog 30 hnub tom qab noj cov tshuaj kawg ntawm cov tshuaj kawm. Paclitaxel yuav muab rau cov leeg nruab nrog kab lossis nruab nrab kab ib zaug ib lub lim tiam rau thawj 3 lub lim tiam ntawm txhua lub voj voog. Cov neeg koom yuav khaws cov ntawv sau cia tshuaj. Lawv yuav taug qab thaum lawv noj tshuaj kawm thiab kev phiv uas lawv muaj. Cov neeg koom yuav tuaj yeem kuaj pob qog noj tawm los tau. Cov neeg tuaj koom tuaj yeem koom nrog txoj kev tshawb no kom txog thaum lawv cov kab mob phem dua lossis lawv muaj kev phiv tshuaj tsis zoo. Cov neeg tuaj koom yuav tau hu xov tooj rov qab txog 30 hnub tom qab noj cov tshuaj kawg ntawm cov tshuaj kawm.
Qhov Chaw: Cov Tsev Kawm Ntawv Hauv Tebchaws ntawm Chaw Kuaj Mob Noj Qab Haus Huv, Bethesda, Maryland
Cabozantinib thiab Temozolomide rau Kev Kho Mob ntawm Kev Tawm Tsam Tsis Zoo lossis Metastatic Leiomyosarcoma lossis Lwm Daim Ntaub Muag Sarcoma
Kev sim qib II no kawm paub tias cabozantinib thiab temozolomide ua haujlwm zoo npaum li cas rau kev kho cov neeg mob leiomyosarcoma lossis lwm cov nqaij mos ua kom tsis tuaj yeem tshem tawm los ntawm kev phais mob (tsis tuaj yeem tiv thaiv) lossis tau kis mus rau lwm qhov chaw hauv lub cev (metastatic). Cabozantinib tuaj yeem nres kev loj hlob ntawm cov qog ntshav los ntawm kev thaiv qee cov enzymes xav tau rau kev loj hlob ntawm tes. Cov tshuaj siv hauv kev siv tshuaj kho mob, xws li temozolomide ua haujlwm nyob rau ntau txoj hauv kev los tiv thaiv kev loj hlob ntawm cov qog hlwb, los ntawm tua cov hlwb, los ntawm kev txwv lawv kom faib, lossis txwv tsis pub kis mus rau lwm qhov. Kev muab cabozantinib thiab temozolomide tuaj yeem ua haujlwm zoo dua li ib leeg hauv kev kho mob rau cov neeg mob leiomyosarcoma lossis lwm cov nqaij mos sarcoma. Cabozantinib yog ib qho tshuaj tshawb xyuas,
Qhov chaw: 7 thaj chaw
Doxorubicin, AGEN1884, thiab AGEN2034 rau Kev Kho Mob ntawm Kev Tshawb Fawb Qib Siab lossis Nruab Nrab Qhov Mob Sarcoma
Kev sim qib II no kawm paub zoo npaum li cas doxorubicin ua ke nrog AGEN1884 thiab AGEN2034 ua haujlwm hauv kev kho mob rau cov neeg mob cov nqaij mos sarcoma uas tau kis mus rau lwm qhov chaw hauv lub cev (ua ntej lossis metastatic). Cov tshuaj siv hauv kev siv tshuaj kho mob, xws li doxorubicin ua haujlwm nyob rau ntau txoj hauv kev los tiv thaiv kev loj hlob ntawm cov qog nqaij hlav, los ntawm tua cov qog, los ntawm kev txwv lawv kom faib, lossis txwv tsis pub kis mus rau lwm qhov. Kev txhaj tshuaj tiv thaiv kab mob nrog monoclonal tiv thaiv kab mob, xws li AGEN1884 thiab AGEN2034, tuaj yeem pab lub cev tiv thaiv lub cev tua cov kabmob, thiab yuav cuam tshuam lub peev xwm ntawm cov qog ntshav kom loj hlob thiab kis tau. Muab cov doxorubicin, AGEN1884, thiab AGEN2034 tuaj yeem ua haujlwm zoo dua hauv kev kho mob rau cov neeg mob mos mos sarcoma piv rau doxorubicin ib leeg.
Qhov chaw nyob: ' Tsev Kawm Qib Siab ntawm Colorado, Denver, Colorado
Pab saib xyuas nws pib-rov ua dua tshiab