Nā ʻano / pahee -ʻaʻaʻa-sarcoma / hoʻomanawanui / rhabdomyosarcoma-lapaʻau-pdq
Nā ʻikepili i loko
Hoʻomaʻamaʻa Rhabdomyosarcoma Childhood (®) - Mana Mana Manaʻo
ʻO ka ʻike ākea e pili ana i ke kamaliʻi Rhabdomyosarcoma
ʻO ka rhabdomyosarcoma kamaliʻi kahi maʻi kahi i kū ai nā pūnaewele malignant (maʻi ʻaʻai) i nāʻiʻo iʻa.
ʻO Rhabdomyosarcoma kahi ʻano sarcoma. ʻO Sarcoma ka maʻi ʻaʻai o nā mea palupalu (e like me ka mākala), nā mea hoʻopili (e like me ka tendon a i ʻole ka cartilage), a i ʻole ka iwi. Hoʻomaka maʻamau ʻo Rhabdomyosarcoma i nā mākala e pili ana i nā iwi a kōkua i ke kino e neʻe. ʻO Rhabdomyosarcoma ka ʻano maʻamau o ka sarcoma palupalu i nā keiki. Hiki iā ia ke hoʻomaka ma nā wahi he nui i ke kino.
ʻEkolu ʻano nui o ka rhabdomyosarcoma:
- Embryonal: Kū pinepine kēia ʻano ma ke poʻo a me ka ʻāʻī ā i ʻole i nā genital a i ʻole nā mimi, akā hiki ke hana ma nā wahi āpau o ke kino. ʻO ia ka ʻano maʻamau o ka rhabdomyosarcoma.
- Alveolar: Hana pinepine kēia ʻano i nā lima a i ʻole nā wāwae, ka umauma, ʻōpū, nā genital, a me nā wahi anal.
- Anaplastic: ʻO kēia ka liʻiliʻi o nā ʻano maʻamau o ka rhabdomyosarcoma i nā keiki.
E ʻike i nā hōʻuluʻulu lapaʻau e hiki mai ana no ka ʻike e pili ana i nā ʻano ʻano ʻē aʻe o ka sarcomaʻiʻo palupalu.
- ʻO ke kamaliʻi palupalu ʻo Sarcoma
- ʻO Sarcoma Pōlū Palekana mākua
Hoʻonui nā kūlana kūlohelohe i ka makaʻu o ka rhabdomyosarcoma kamaliʻi.
ʻO nā mea āpau e hoʻonui i ka makaʻu o ka loaʻa ʻana o ka maʻi i kapa ʻia he kumu weliweli. ʻO ka loaʻa ʻana o kahi mea pilikia ʻaʻole ia he kumu e loaʻa ʻoe i ka maʻi ʻaʻai. ʻaʻohe o nā kumu pilikia ʻaʻole ia he kumu ʻaʻole ʻoe e loaʻa i ka maʻi ʻaʻai. E kamaʻilio me kāu kauka inā makemake ʻoe e pilikia paha kāu keiki.
ʻO nā kumu pilikia no ka rhabdomyosarcoma me ka loaʻa ʻana o nā maʻi hoʻoilina i lalo:
- Li-Fraumeni maʻi.
- Pleuropulmonary blastoma.
- ʻO Neurofibromatosis ʻano 1 (NF1).
- ʻO Costello Syndrome.
- Beckwith-Wiedemann maʻi.
- Noonan syndrome.
ʻO nā keiki i loaʻa i kahi kaumaha hānau nui a i ʻoi aku ka nui ma mua o ka mea i manaʻo ʻia i ka wā hānau hiki ke hoʻonui i ka makaʻu o ka embryonal rhabdomyosarcoma.
I ka hapanui o nā hihia, ʻike ʻole ʻia ke kumu o ka rhabdomyosarcoma.
ʻO kahi hōʻailona o ka rhabdomyosarcoma kamaliʻi he puʻupuʻu a ʻōhū paha ia e hoʻonui nui ana.
Hoʻokumu ʻia nā hōʻailona a me nā ʻōuli e ka rhabdomyosarcoma kamaliʻi a i ʻole nā ʻano ʻē aʻe. ʻO nā hōʻailona a me nā ʻōuli e kū ana ma muli o ka maʻi ʻaʻai. E nīnau me ke kauka o kāu keiki inā loaʻa i kāu keiki kekahi o kēia mau mea:
- ʻO kahi puʻupuʻu a ʻōhū paha e hele a nui a hele ʻole paha. He ʻeha paha.
- ʻŌpuʻu o ka maka.
- ʻEha poʻo.
- Ka pilikia i ka mimiki ʻana a i ʻole ka neʻe ʻana o ka ʻōpū.
- Koko i ka mimi.
- Kahe i ka ihu, ka ʻāʻī, ka ʻōpū, a i ʻole ka pololei.
Hoʻohana ʻia nā hoʻokolohua diagnostics a me kahi biopsy e ʻike ai (loaʻa) a ʻike ʻia ka rhabdomyosarcoma kamaliʻi.
ʻO nā hoʻokolohua diagnostical e hana ʻia e pili ana i kahi o nā maʻi ʻaʻai. Hiki ke hoʻohana ʻia nā hoʻāʻo a me nā kaʻina hana aʻe:
- ʻO ka hoʻāʻo kino a me ka mōʻaukala: kahi hōʻike o ke kino e nānā i nā hōʻailona laulā o ke olakino, e like me ka nānā ʻana i nā hōʻailona o ka maʻi, e like me nā puʻupuʻu a i ʻole nā mea ʻē aʻe e ʻano ʻē. E lawe ʻia kahi moʻolelo o nā ʻano olakino o ka mea maʻi a me nā maʻi i hala a me nā mālama ʻana.
- X-ray: ʻO kahi lā x o nā mea a me nā iwi i loko o ke kino, e like me ka umauma. ʻO ka x-ray kahi ʻano kukuna ikehu e hiki ke hele ma waena o ke kino a ma ke kiʻi ʻoniʻoni, e hana ana i kiʻi o nā wahi i loko o ke kino.
- CT scan (CAT scan): Kahi hana e hana ai i kahi o nā kiʻi kikoʻī o nā wahi i loko o ke kino, e like me ka umauma, ʻōpū, pelvis, a i ʻole nā lymph node, i lawe ʻia mai nā kihi ʻokoʻa. Hana ʻia nā kiʻi e kahi kamepiula i hoʻopili ʻia i kahi mīkini x-ray. Hoʻokomo ʻia paha ke kala i loko o ke aa a i ʻole ale ʻia e kōkua i nā ʻōpū a i ʻole nā kino i hōʻike hou aku me ka maopopo. Kāhea ʻia kēia kaʻina hana he tomography i helu ʻia, kamepiula tomography, a i ʻole he tomography axial computerized.
- MRI (kiʻi resonance ʻume mākenēki): kahi hana e hoʻohana ai i ka magnet, nā nalu lekiō, a me kahi kamepiula e hana i nā kiʻi kikoʻī o nā wahi o ke kino, e like me ka iwi poʻo, lolo, a me nā lymph node. Kāhea ʻia kēia kaʻina hana he kiʻi nukelea kiʻi resonance (NMRI).
- PET scan (positron emission tomography scan): kahi hana e loaʻa ai nā puʻupuʻu tumo malignant i loko o ke kino. Hoʻokomo ʻia kahi liʻiliʻi o ka glucose radioactive (kō) i loko o kahi aa koko. Hoʻopili ka scanner PET a puni ke kino a hana i kahi kiʻi o kahi e hoʻohana ʻia ai ka glucose i ke kino. ʻOi aku ka mālamalama o nā hunaola tumo ma ke kiʻi no ka mea ʻoi aku ka hana a lawe i ka glucose ma mua o ka hana ʻana o nā hunaola maʻamau.
- ʻImi iwi: kahi hana e nānā ai inā aia he wikiwiki e hoʻokaʻawale i nā hunaola, e like me nā hunaola maʻi ʻaʻai, i ka iwi. Hoʻokomo ʻia kahi mea liʻiliʻi loa o nā mea radioactive i loko o ke aa a hele i waena o ke kahe o ke koko. Hōʻiliʻili ka mea lekiō i nā iwi me ka maʻi ʻaʻai a ʻike ʻia e kahi scanner.
- ʻO ka ʻiʻo o ka iwi iwi a me ka biopsy: Ka hemo ʻana o ka iwi iwi, ke koko, a me kahi ʻāpana o ka iwi me ka hoʻokomo ʻana i kahi kui kolo i loko o ka iwi ākea Lawe ʻia nā laʻana mai nā hipbones ʻelua. ʻIke kahi pathologist i ka momona o ka iwi, ke koko, a me ka iwi ma lalo o kahi microscope e nānā i nā hōʻailona o ka maʻi ʻaʻai.
- Lumbar puncture: kahi hana i hōʻiliʻili ʻia e hōʻiliʻili ai i ka wai cerebrospinal (CSF) mai ke kolamu iwi kuamoʻo. Hana ʻia kēia ma ke kau ʻana i kahi nila i waena o ʻelua iwi i ka iwi kuamoʻo a i loko o ka CSF a puni ka iwi kuamoʻo a hemo i kahi hāpana o ka wai. Nānā ʻia ka laʻana o CSF ma lalo o kahi microscope no nā ʻōuli o nā hunaola maʻi ʻaʻai. Kāhea ʻia kēia kaʻina hana he LP a i ʻole ka piulawi.
Inā hōʻike kēia mau hoʻokolohua aia paha kahi rhabdomyosarcoma, hana ʻia kahi biopsy. ʻO kahi biopsy ka hemo ʻana o nā hunaola a i ʻole nāʻaʻaʻa i hiki iā lākou ke nānā ma lalo o kahi microscope e kahi pathologist e nānā i nā hōʻailona o ka maʻi ʻaʻai. Ma muli o ka mālama ʻana i ke ʻano o ka rhabdomyosarcoma, pono e nānā ʻia nā laʻana biopsy e kahi pathologist i loaʻa ka ʻike i ke kuhi ʻana i ka rhabdomyosarcoma.
Hiki ke hoʻohana ʻia kekahi o nā ʻano biopsies:
- ʻO ka biopsy aspiration maikaʻi-nila (FNA): Ka hemo ʻana o nā aʻa a i ʻole ka wai e hoʻohana ana i ka nila kuina.
- ʻO ka biopsy o ka nila nui: ʻO ka hemo ʻana o nā kiko me ka hoʻohana ʻana i ka nila nui. Hiki ke alakaʻi ʻia kēia kaʻina hana me ka hoʻohana ʻana i ka ultrasound, CT scan, a i ʻole MRI.
- Wehe i ka biopsy: Ka lawe ʻia ʻana o nā mea ma o ka ʻokiʻoki (ʻoki) i hana ʻia i ka ʻili.
- ʻO ka biopsy lymph node Sentinel: ʻO ka lawe ʻana i ka lymph node sentinel i ke kau ʻana. ʻO ka lymph node sentinel ka lua o nā lymph node ma kahi hui o nā lymph node e loaʻa ai ka hoʻoheheʻe lymphatic mai ka tumo mua. ʻO ia ka pūnana lymph mua e laha aku ai ka maʻi ʻaʻai mai a ka tumo mua. Hoʻokomo ʻia kahi mea lekiō a me / a i ʻole ke kala polū ma kahi kokoke i ka tumo. Kahe ka mea a kala paha ma o nā kahena lymph i nā lymph node. Lawe ʻia ka pona lymph mua e loaʻa ai ka waiwai a kala paha. ʻIke kahi pathologist i ke kiko ma lalo o kahi microscope e nānā no nā hunaola maʻi ʻaʻai. Inā ʻaʻole i loaʻa nā hunaola maʻi ʻaʻai, ʻaʻole pono paha e hemo i nā pūnana lymph. I kekahi manawa, loaʻa kahi lymph node sentinel i kahi ʻoi aku o hoʻokahi hui o nā aka.
E hana ʻia paha nā hoʻokolohua aʻe ma ka laʻana o nā kiko i lawe ʻia.
- ʻO ka microscopy māmā: kahi hōʻike keʻena hoʻokolohua kahi e ʻike ʻia ai nā pūnaewele i kahi mahele o nā mea i ʻike ʻia ma lalo o nā microscope mana a me ka mana kiʻekiʻe e nānā no kekahi mau loli i nā hunaola.
- Immunohistochemistry: kahi hōʻike e hoʻohana ai i nā mea pale e nānā i kekahi mau antigens i kahi laʻana o nā mea kiko. Hoʻohui pinepine ʻia ka antibody i kahi mea radioactive a i ʻole ke kala e hoʻomālamalama ai ka iʻa ma lalo o kahi microscope. Hiki ke hoʻohana ʻia kēia ʻano hoʻokolohua e haʻi i ka ʻokoʻa ma waena o nā ʻano maʻi ʻaʻai.
- FISH (fluorescence in situ hybridization): kahi hoʻokolohua hoʻokolohua i hoʻohana ʻia e nānā i nā genes a i ʻole nā chromosome i nā pūnaewele a me nā aʻa. Hana ʻia nā ʻāpana o ka DNA i loaʻa ka pena fluorescent i loko o ke keʻena hoʻokolohua a hoʻohui ʻia i nā hunaola a i ʻole nāʻaʻaʻa ma kahi kiʻi aniani. Ke hoʻopili aku kēia mau ʻāpana o DNA i kekahi mau ʻāpana a i ʻole nā wahi o nā chromosome ma ka paheʻe, hoʻomālamalama lākou ke nānā ʻia ma lalo o kahi microscope me kahi kukui kūikawā. Hoʻohana ʻia kēia ʻano hoʻokolohua e loaʻa ai kekahi mau loli.
- Hoʻohālikelike hoʻohuli - polymerase chain reaction (RT – PCR) hōʻike: kahi hoʻokolohua hoʻokolohua kahi e aʻo ʻia ai nā pūnaewele i ka hoʻohana ʻana i nā kemika e nānā no kekahi mau loli i ke ʻano a i ʻole ka hana o nā genes.
- Nānā Cytogenetic: kahi hōʻike keʻena hoʻokolohua kahi e ʻike ʻia ai nā hunaola i kahi hāpana o ke kiko ma lalo o kahi microscope e nānā ai i kekahi mau hoʻololi i nā chromosome.
Kū kekahi mau kumu i ka wānana (kahi o ke ola ʻana) a me nā koho lapaʻau.
ʻO ka wānana (loaʻa o ke ola) a me nā koho lapaʻau e pili i kēia:
- ʻO ka makahiki o ka mea hoʻomanawanui.
- Ma kahi o ke kino i hoʻomaka ai ka tumo.
- Ka nui o ka tumo i ka manawa o ke kuhi.
- Inā ua hemo loa ka tumo e ke ʻoki.
- Ke ʻano o ka rhabdomyosarcoma (embryonal, alveolar, a i ʻole anaplastic).
- Inā paha aia kekahi mau hoʻololi i nā gen.
- Inā ua pālahalaha ka tumo i nā ʻāpana ʻē aʻe o ke kino i ka manawa o ke kuhi.
- Inā ʻo ka tumo i loko o nā lymph node i ka manawa o ke kuhi.
- Ke pane paha ka tumo i ka chemotherapy a me / a i ʻole radiation radiation.
No nā mea maʻi me ka maʻi ʻaʻai kūpikipiki, ka wānana a me ka hoʻomaʻamaʻa pili pū kekahi i kēia:
- Kahi i loko o ke kino i hoʻi hou ka ʻōpala (hoʻi hou).
- Ehia mau manawa i hala ma waena o ka hopena o ka mālama ʻana i ka maʻi ʻaʻai a i ka manawa i hoʻi hou ai ka maʻi ʻaʻai.
- Inā mālama ʻia ka tumo me ka radiation therapy.
Nā papa o ke kamaliʻi Rhabdomyosarcoma
NA MANA KUNI
- Ma hope o ka ʻike ʻia ʻana o ka rhabdomyosarcoma kamaliʻi, hoʻokumu ʻia ka lapaʻau ma kekahi ʻāpana ma ke kahua o ka maʻi ʻaʻai a i kekahi manawa hoʻokumu ʻia ia inā ua lawe ʻia nā maʻi maʻi āpau e ka ʻoki kino.
- ʻEkolu ala e hoʻolaha ai ka maʻi ʻaʻai i loko o ke kino.
- E laha paha ka maʻi ʻaʻai mai kahi i hoʻomaka ai i nā ʻāpana ʻē aʻe o ke kino.
- Hana ʻia ka hoʻonohonoho ʻana o ka rhabdomyosarcoma kamaliʻi i ʻekolu mau ʻāpana.
- Hoʻokumu ʻia ka ʻōnaehana hoʻonohonoho i ka nui o ka tumo, kahi i loko o ke kino, a inā ua pālahalaha ʻia i nā ʻāpana ʻē aʻe o ke kino.
- Kahua 1
- Kahua 2
- Kahua 3
- Kahua 4
- Hoʻokumu ʻia ka ʻōnaehana hoʻonohonoho inā ua laha ka maʻi ʻaʻai a inā ua lawe ʻia nā maʻi maʻi āpau e ka ʻoki kino:
- Pūʻulu I
- Pūʻulu II
- Pūʻulu III
- Pūʻulu IV
- Hoʻokumu ʻia ka pūʻulu makaʻu i ka ʻōnaehana hoʻonohonoho a me ka ʻōnaehana hoʻonohonoho.
- ʻO rhabdomyosarcoma kamaliʻi kūlana haʻahaʻa haʻahaʻa
- ʻO rhabdomyosarcoma kamaliʻi pōpilikia waena
- ʻO rhabdomyosarcoma kamaliʻi kūlana kiʻekiʻe
Ma hope o ka ʻike ʻia ʻana o ka rhabdomyosarcoma kamaliʻi, hoʻokumu ʻia ka lapaʻau ma kekahi ʻāpana ma ke kahua o ka maʻi ʻaʻai a i kekahi manawa hoʻokumu ʻia ia inā ua lawe ʻia nā maʻi maʻi āpau e ka ʻoki kino.
ʻO ke kaʻina hana e ʻike ai inā ua pālahalaha ka maʻi ʻaʻai i loko o ka aʻa a i ʻole nā ʻāpana ʻē aʻe o ke kino i kapa ʻia he staging. He mea nui ia e ʻike i ke kahua i mea e hoʻolālā ai i ka lāʻau. E hoʻohana ke kauka i nā hopena o nā hōʻike hōʻoia e kōkua ai e ʻike i ke kahua o ka maʻi.
Hoʻokumu ʻia ka mālama ʻana no ka rhabdomyosarcoma kamaliʻi ma kahi ʻāpana o ke kahua a i kekahi manawa i ka nui o ka maʻi ʻaʻai e waiho ana ma hope o ke kaha ʻana e wehe i ka tumo. E hoʻohana ka pathologist i kahi microscope e nānā i nā mea i lawe ʻia i ka wā o ke ʻoki ʻana, e laʻa me nā kiko kiko mai nā kihi o nā wahi kahi i lawe ʻia ai ka maʻi ʻaʻai a me nā lymph node. Hana ʻia kēia e ʻike inā lawe ʻia aku nā hunaola maʻi āpau i ka wā o ke ʻoki.
ʻEkolu ala e hoʻolaha ai ka maʻi ʻaʻai i loko o ke kino.
Hiki ke pālahalaha ʻia ka maʻi ʻaʻai ma o nā meaola, ka ʻōnaehana lymph, a me ke koko.
- Kāpena. Hoʻolahalaha ka maʻi ʻaʻai mai kahi i hoʻomaka ai i ka ulu ʻana i nā wahi kokoke.
- ʻŌnaehana Lymph. Hoʻolahalaha ka maʻi ʻaʻai mai kahi i hoʻomaka ai i ke komo ʻana i ka ʻōnaehana lymph. Hele ka maʻi ʻaʻai ma o nā kīʻaha lymph i nā ʻāpana ʻē aʻe o ke kino.
- Koko. Hoʻolahalaha ka maʻi ʻaʻai mai kahi i hoʻomaka ai i ke komo ʻana i ke koko. Hele ka maʻi ʻaʻai ma o nā kīʻaha koko i nā ʻāpana ʻē aʻe o ke kino.
E laha paha ka maʻi ʻaʻai mai kahi i hoʻomaka ai i nā ʻāpana ʻē aʻe o ke kino.
Ke pālahalaha ʻia ka maʻi ʻaʻai i kekahi ʻāpana o ke kino, ua kapa ʻia ia ʻo metastasis. E haki nā hunaola maʻi 'aʻai mai kahi a lākou i hoʻomaka ai (ka tumo mua) a hele i loko o ka ʻōnaehana lymph a i ʻole ke koko.
ʻŌnaehana Lymph. Komo ka maʻi ʻaʻai i loko o ka ʻōnaehana lymph, hele ma waena o nā kīʻaha lymph, a hana i kahi tumo (tumo metastatic) i kekahi ʻāpana o ke kino. Koko. Komo ke kanesa i loko o ke koko, hele ma waena o nā kīʻaha koko, a hana i kahi tumo (tumo metastatic) i kekahi ʻāpana o ke kino. ʻO ka tumo metastatic ka ʻano like o ke kanesa me ka tumo mua. ʻO kahi laʻana, inā pālahalaha ka rhabdomyosarcoma i ka akemā, ʻo nā pūnaeho maʻi ʻaʻai i loko o ka akemā he mau puʻupaʻa rhabdomyosarcoma maoli ia. ʻO ka rhabdomyosarcoma metastatic ka maʻi, ʻaʻole ka maʻi ʻaʻa maʻi.
Hana ʻia ka hoʻonohonoho ʻana o ka rhabdomyosarcoma kamaliʻi i ʻekolu mau ʻāpana.
Hoʻonohonoho ʻia ka rhabdomyosarcoma kamaliʻi ma o ka hoʻohana ʻana i ʻekolu ala ʻokoʻa e wehewehe ai i ka maʻi ʻaʻai.
- ʻO kahi ʻōnaehana hoʻonohonoho.
- ʻŌnaehana hoʻohuihui.
- ʻO kahi hui pilikia.
Hoʻokumu ʻia ka ʻōnaehana hoʻonohonoho i ka nui o ka tumo, kahi i loko o ke kino, a inā ua pālahalaha ʻia i nā ʻāpana ʻē aʻe o ke kino.
Kahua 1
I ka pae 1, he nui ka tumo, ua pāhola paha i nā lymph node, a loaʻa ma hoʻokahi wale nō o nā pūnaewele "maikaʻi" e hiki mai ana:
- Maka a wahi paha a puni ka maka.
- ʻO ke poʻo a me ka ʻāʻī (akā ʻaʻole i loko o ke kiko kokoke i ka lolo a me ka iwi kuamoʻo).
- ʻO Gallbladder a me nā kaha bile.
- Ureter a urethra paha.
- Nā hoʻāʻo, ka ovary, ka ʻōpū, a me ka uterus.
Rhabdomyosarcoma e hana i kahi pūnaewele "ʻoluʻolu" he prognosis ʻoi aku ka maikaʻi. Inā ʻo ka pūnaewele kahi e kū ai ka maʻi ʻaʻai ʻaʻole kekahi o nā pūnaewele maikaʻi i helu ʻia ma luna, ua ʻōlelo ʻia he pūnaewele "maikaʻi ʻole" ia.
Kahua 2
I ka pae 2, loaʻa ka maʻi ʻaʻai i loko o kahi pūnaewele "maikaʻi ʻole" (kahi ʻāpana i wehewehe ʻole ʻia ma ke ʻano he "ʻoluʻolu" i ka pae 1). ʻAʻole i ʻoi aku ka nui o ka tumo ma mua o 5 mau kenimika a ʻaʻole i pālahalaha ʻia i nā nū lymph.
Kahua 3
I ka pae 3, loaʻa ka maʻi ʻaʻai i loko o kahi pūnaewele "maikaʻi ʻole" (kahi ʻāpana i wehewehe ʻole ʻia ma ke ʻano he "ʻoluʻolu" i ka pae 1) a ʻo kekahi o kēia mau mea ʻoiaʻiʻo.
- ʻAʻole i ʻoi aku ka nui o ka tumo ma mua o 5 mau kenimika a ua pālahalaha ʻia ka maʻi ʻaʻai i nā pūnana lymph kokoke.
- ʻOi aku ka nui o ka tumo ma mua o 5 mau kenimika a ua pāhola paha ka maʻi ʻaʻai i nā pūnana lymph kokoke.
Kahua 4
I ka pae 4, he nui paha ka tumo a ua pāhola paha ka maʻi ʻaʻai i nā pūnana lymph kokoke. Ua pālahalaha ka maʻi ʻaʻai i nā ʻāpana mamao o ke kino, e like me ka hū, ka iwi iwi, a me ka iwi.
Hoʻokumu ʻia ka ʻōnaehana hoʻonohonoho inā ua laha ka maʻi ʻaʻai a inā ua lawe ʻia nā maʻi maʻi āpau e ka ʻoki kino:
Pūʻulu I
ʻIke ʻia ka maʻi ʻaʻai ma kahi wale nō i hoʻomaka ai a hemo loa ia e ke kaha. Lawe ʻia ka kele mai nā lihi o kahi i wehe ʻia ai ka tumo. Nānā ʻia ke kiko ma lalo o ka microscope e kahi pathologist a ʻaʻohe pūnana maʻi ʻaʻai i loaʻa.
Pūʻulu II
Māhele ʻia ka hui II i nā hui IIA, IIB, a me IIC.
- IIA: Ua kāʻili ʻia ke kanesa e ka ʻoki kino akā ua ʻike ʻia nā hunaola maʻi ʻaʻai ke lawe ʻia ke kiko, mai nā lihi o kahi i hemo aku ai ka ʻōpala, i ʻike ʻia ma lalo o kahi microscope e kahi pathologist.
- IIB: Ua pālahalaha ka maʻi ʻaʻai i nā lymph node kokoke a ua lawe ʻia ka maʻi ʻaʻai a me nā lymph e ke ʻoki.
- IIC: Ua pālahalaha ka maʻi ʻaʻai i nā lymph node kokoke, ua lawe ʻia ka maʻi ʻaʻai a me nā lymph e ke ʻoki ʻana, a ma ka liʻiliʻi he hoʻokahi o kēia mau mea:
- Līkū i lawe ʻia mai nā kaʻe o kahi i lawe ʻia ka tumo i nānā ʻia ma lalo o kahi microscope e kahi pathologist a ʻike ʻia nā hunaola maʻi ʻaʻai.
- ʻO ka lymph node mamao loa mai ka tumo i lawe ʻia i nānā ʻia ma lalo o kahi microscope e kahi pathologist a ʻike ʻia nā hunaola maʻi ʻaʻai.
Pūʻulu III
Ua kāpae hapa ʻia ka maʻi ʻaʻai e ka biopsy a i ʻole ke ʻoki ʻana akā koe kekahi koena i koe i hiki ke ʻike ʻia e ka maka.
Pūʻulu IV
- Ua pālahalaha ʻia ka maʻi ʻaʻai i nā ʻāpana mamao o ke kino ke ʻike ʻia ka maʻi ʻaʻai.
- ʻIke ʻia nā hunaola maʻi ʻaʻai e kahi hōʻike kiʻi; a i ʻole
Aia nā hunaola maʻi ʻaʻai i loko o ka wai a puni ka lolo, ka pupu o ka iwi, a i ʻole nā akemāmā, a i ʻole ka wai i loko o ka ʻōpū aiʻole nā tumors i loaʻa i kēlā mau wahi.
Hoʻokumu ʻia ka pūʻulu makaʻu i ka ʻōnaehana hoʻonohonoho a me ka ʻōnaehana hoʻonohonoho.
Hōʻike ka hui makaʻu i ka manawa kūpono e hoʻi hou ai ka rhabdomyosarcoma (hoʻi hou). Pono e loaʻa i kēlā me kēia keiki i mālama ʻia no ka rhabdomyosarcoma i ka chemotherapy e hoʻemi i ka manawa e hoʻi hou ai ka maʻi ʻaʻai. ʻO ke ʻano o ka lāʻau anticancer, ka mahele lāʻau, a me ka helu o nā hana i hāʻawi ʻia e pili ana i ka loaʻa o ke kamepiula i kahi kūlana haʻahaʻa, waena waena, a i ʻole rhabdomyosarcoma kiʻekiʻe.
Hoʻohana ʻia nā pūʻulu pilikia aʻe:
ʻO rhabdomyosarcoma kamaliʻi kūlana haʻahaʻa haʻahaʻa
- ʻO ka rhabdomyosarcoma kamaliʻi haʻahaʻa haʻahaʻa haʻahaʻa kekahi o kēia:
Kahi tumo embryonal o kēlā me kēia nui i loaʻa ma kahi pūnaewele "ʻoluʻolu". Aia paha he tumo i koe ma hope o ke kahakaha ʻana e hiki ke ʻike ʻia me ka ʻole o kahi microscope. Ua pālahalaha paha ka maʻi ʻaʻai i nā pūnana lymph kokoke. ʻO nā ʻāpana aʻe nā pūnaewele "ʻoluʻolu":
- Maka a wahi paha a puni ka maka.
- ʻO ke poʻo a me ka ʻāʻī (akā ʻaʻole ma ka mea kiko kokoke i ka pepeiao, ihu, sinus, a i ʻole kumu o ka iwi poʻo).
- ʻO Gallbladder a me nā kaha bile.
- Ureter a i ʻole urethra.
- Nā hoʻāʻo, ka ovary, ka ʻōpū, a me ka uterus.
Kahi tumo embryonal o kēlā me kēia nui i ʻike ʻole ʻia ma kahi pūnaewele "ʻoluʻolu". Aia paha he tumo i koe ma hope o ke kahakaha ʻana e hiki ke ʻike wale ʻia me kahi microscope. Ua pālahalaha paha ka maʻi ʻaʻai i nā pūnana lymph kokoke.
ʻO rhabdomyosarcoma kamaliʻi pōpilikia waena
ʻO rhabdomyosarcoma kamaliʻi pōpilikia waena kekahi o kēia mau mea:
- Kahi tumo embryonal o kēlā me kēia nui i ʻike ʻole ʻia ma kekahi o nā pūnaewele "ʻoluʻolu" i helu ʻia ma luna. Aia kekahi tumo i koe ma hope o ke kahakaha ʻana, i hiki ke ʻike ʻia me ka ʻole o kahi microscope. Ua pālahalaha paha ka maʻi ʻaʻai i nā pūnana lymph kokoke.
- ʻO kahi tumo alveolar o kēlā me kēia nui ma kahi pūnaewele "ʻoluʻolu" a i ʻole "maikaʻi ʻole". Aia paha he tumo i koe ma hope o ke kahakaha ʻana e hiki ke ʻike ʻia me ka ʻole o kahi microscope. Ua pālahalaha paha ka maʻi ʻaʻai i nā pūnana lymph kokoke.
ʻO rhabdomyosarcoma kamaliʻi kūlana kiʻekiʻe
ʻO ka rhabdomyosarcoma kamaliʻi kūlana kiʻekiʻe paha ka ʻano embryonal a i ʻole ke ʻano alveolar. Ua pālahalaha paha ia i nā nū lymph kokoke a ua pāhola ʻia i hoʻokahi a ʻoi paha o kēia mau mea:
- ʻO nā ʻāpana ʻē aʻe o ke kino ʻaʻole kokoke i kahi o ka tumo i hana mua ai.
- ʻO ka wai a puni ka lolo a i ʻole ke kaula iwi.
- Fluid i loko o ka hāhā a i ʻole ka ʻōpū.
ʻO Rhabdomyosarcoma Kamaliʻi hou
ʻO ka rhabdomyosarcoma kamaliʻi hou ka maʻi ʻaʻai i hoʻi hou (hoʻi mai) ma hope o ka mālama ʻia ʻana. E hoʻi paha ka maʻi ʻaʻai ma ka wahi like a i ʻole nā ʻāpana ʻē aʻe o ke kino, e like me ka hū, ka iwi, a me ka iwi o ka iwi. ʻO ka liʻiliʻi, hoʻi mai paha ka rhabdomyosarcoma i ka umauma i nā wahine ʻōpio a i ke ake.
Laulā Manaʻo Option Oponopono
NA MANA KUNI
- Aia nā ʻano lapaʻau like ʻole no nā mea maʻi me ka rhabdomyosarcoma kamaliʻi.
- Pono nā kamaliʻi me ka rhabdomyosarcoma e mālama i kā lākou lapaʻau ʻana e kahi hui o nā lawelawe mālama ola he loea i ka mālama ʻana i ka maʻi ʻaʻai i nā keiki.
- ʻO ka mālama ʻana i ka rhabdomyosarcoma kamaliʻi e kumu i nā hopena ʻaoʻao.
- Hoʻohana ʻia ʻekolu ʻano o ka mālama maʻamau.
- ʻOki kino
- Lapaʻau hoʻomākala
- ʻO Chemotherapy
- Ke hoʻāʻo ʻia nei nā ʻano lapaʻau hou i nā hoʻokolohua hoʻokolohua.
- Immunotherapy
- Pahuhopu kau ʻia
- Makemake paha nā mea maʻi e noʻonoʻo e pili ana i ka hoʻokolokolo ʻana.
- Hiki i nā mea maʻi ke komo i nā hoʻokolohua hoʻokolohua ma mua, i ka wā, a ma hope paha o ka hoʻomaka ʻana i kā lākou mālama maʻi ʻaʻai.
- Pono paha nā hoʻokolohua ukali.
Aia nā ʻano lapaʻau like ʻole no nā mea maʻi me ka rhabdomyosarcoma kamaliʻi.
Kūlana maʻamau kekahi mau hōʻailona (ʻo ka lāʻau i hoʻohana ʻia i kēia manawa), a ʻo kekahi e hoʻāʻo ʻia nei i nā hoʻokolohua hoʻokolohua. ʻO kahi hoʻokolohua hoʻokolohua lapaʻau kahi noiʻi noiʻi i manaʻo ʻia e kōkua i ka hoʻomaikaʻi ʻana i nā mālama ʻana i kēia manawa a i ʻole loaʻa ka ʻike e pili ana i nā mālama hou no nā maʻi me ka maʻi ʻaʻai. Ke hōʻike nā hoʻokolohua hoʻokolohua ʻoi aku ka maikaʻi o kahi lapaʻau hou ma mua o ka maʻamau maʻamau, lilo paha ka lāʻau hou i ka lapaʻau maʻamau.
Ma muli o ka loaʻa ʻole o ka maʻi ʻaʻai i nā keiki, pono e noʻonoʻo ʻia i ka hoʻokolokolo ʻana. ʻO kekahi mau hoʻokolohua hoʻokolohua e hāmama wale i nā mea maʻi i hoʻomaka ʻole i ka lāʻau.
Pono nā kamaliʻi me ka rhabdomyosarcoma e mālama i kā lākou lapaʻau ʻana e kahi hui o nā lawelawe mālama ola he loea i ka mālama ʻana i ka maʻi ʻaʻai i nā keiki.
Ma muli o ka hiki i ka rhabdomyosarcoma ke hana i nā ʻāpana like ʻole o ke kino, hoʻohana ʻia nā ʻano ʻano like ʻole. E mālama ʻia ka lapaʻau ʻana e kahi oncologist pediatric, he kauka i loea i ka mālama ʻana i nā keiki me ka maʻi ʻaʻai. Hana ka oncologist pediatric me nā mea lawelawe olakino ʻē aʻe i loea i ka mālama ʻana i nā keiki me ka rhabdomyosarcoma a i loea i kekahi mau wahi o ka lāʻau. Pākuʻi ʻia kēia mau mea i lalo:
- Kahuna Pediatrician.
- Kauka ʻōpio.
- Oncologist uila.
- Hematologist Pediatric.
- ʻO radiologist Pediatric.
- ʻO ka loea kahu maʻi Pediatric.
- ʻO Geneticist a i ʻole genetics cancer aʻoaʻo aʻoaʻo.
- Limahana limahana.
- Lapaʻau hoʻōla.
ʻO ka mālama ʻana i ka rhabdomyosarcoma kamaliʻi e kumu i nā hopena ʻaoʻao.
No ka ʻike e pili ana i nā hopena i hoʻomaka i ka wā o ka mālama ʻana no ka maʻi ʻaʻai, ʻike i kā mākou ʻaoʻao ʻaoʻao ʻaoʻao.
ʻO nā hopena ʻē aʻe mai ka mālama ʻana i ka maʻi ʻaʻai e hoʻomaka ma hope o ka mālama ʻana a hoʻomau no nā mahina a i ʻole mau makahiki e kapa ʻia nā hopena hopena. ʻO nā hopena hope loa o ka mālama ʻana i ka maʻi ʻaʻai no rhabdomyosarcoma e hoʻopili pū paha:
- Nā pilikia o ke kino.
- Nā loli i ke ʻano, nā manaʻo, ka noʻonoʻo, ke aʻo ʻana, a me ka hoʻomanaʻo paha.
- Nā maʻi ʻelua (nā ʻano maʻi ʻaʻai hou).
E mālama a kāohi ʻia paha kekahi mau hopena hopena. He mea nui e kamaʻilio pū me nā kauka o kāu keiki e pili ana i nā hopena o ka mālama ʻana i ka maʻi ʻaʻai i kāu keiki. (E ʻike i ka hōʻuluʻulu e pili ana i nā hopena hope o ka mālama ʻana no ka maʻi ʻaʻai kamaliʻi no ka ʻike hou aku.)
Hoʻohana ʻia ʻekolu ʻano o ka mālama maʻamau.
ʻOki kino
Ke ʻoki (wehe i ka maʻi ʻaʻai i kahi hana) hoʻohana ʻia e mālama i ka rhabdomyosarcoma kamaliʻi. Hana pinepine ʻia kahi ʻano ʻoki lāʻau i kapa ʻia he ākea kūloko. ʻO ka excision ākea ākea ka wehe ʻana o ka tumo a me kekahi o nā mea a puni iā ia, me nā lymph node. Pono paha kahi ʻoki ʻelua e wehe i nā maʻi ʻaʻai āpau. Inā hana ʻia ke ʻoki a me ke ʻano o ke kaha ʻana e pili ana i kēia:
- Ma kahi o ke kino i hoʻomaka ai ka tumo.
- Ka hopena o ke ʻoki ʻana ma ke ala e nānā ai ke keiki.
- Ka hopena o ke kaha ʻana ma nā hana nui a ke keiki.
- Pehea i pane ai ka tumo i ka chemotherapy a i ʻole ka radiation therapy i hāʻawi ʻia ai ma mua.
I ka hapanui o nā keiki me ka rhabdomyosarcoma, ʻaʻole hiki ke hemo i nā tumo āpau e ke ʻoki kino.
Hiki i ka Rhabdomyosarcoma ke hana i nā wahi like ʻole o ke kino a ʻokoʻa ka ʻoki ʻana no kēlā me kēia pūnaewele. ʻO ke ʻoki kino e mālama ai i ka rhabdomyosarcoma o ka maka a i ʻole nā ʻāpana genital he biopsy. Chemotherapy, a i kekahi manawa radiation radiation, hiki ke hāʻawi ʻia ma mua o ke kaha ʻana e hōʻemi i nā tumors nui.
Ma hope o ka hemo ʻana o ke kauka i nā maʻi ʻaʻai āpau i hiki ke ʻike ʻia i ka manawa o ke ʻoki ʻana, e hāʻawi ʻia nā mea maʻi i ka chemotherapy ma hope o ke kaha ʻana e pepehi i nā hunaola maʻi ʻea i koe. Hiki ke hāʻawi ʻia i ka radiation radiation. ʻO ka lāʻau i hāʻawi ʻia ma hope o ke kaha ʻana, e hoʻohaʻahaʻa i ka makaʻu e hoʻi mai ka maʻi ʻaʻai, i kapa ʻia ʻo adjuvant therapy.
Lapaʻau hoʻomākala
ʻO ka radiation radiation kahi lāʻau lapaʻau maʻi maʻi e hoʻohana i nā kukuna x nui ikaika a i ʻole nā ʻano radiation e hoʻomake i nā hunaola maʻi ʻaʻai a i ʻole hoʻokū iā lākou mai ka ulu ʻana. ʻElua ʻano o radiation radiation:
- Hoʻohana ka radiation radiation kūwaho i kahi mīkini ma waho o ke kino e hoʻouna i ka radiation i ka maʻi ʻaʻai. Hiki i kekahi mau ala o ka hāʻawi ʻana i ka radiation therapy ke pale i ka radiation mai ka hōʻino ʻana i nā mea olakino kokoke. ʻO kēia ʻano o ka radiation radiation kū i waho e like me kēia:
- ʻO ka radiation radiation Conformal: he ʻano radiation radiation kūwaho kahi hoʻohana i kahi kamepiula e hana i kahi kiʻi 3-dimensional (3-D) o ke tumo a hoʻohālikelike i nā kaola kukuna e kū pono i ka tumo. ʻAe kēia i kahi lāʻau kiʻekiʻe o ka pāhawewe e hiki i ka tumo a hoʻemi iki i ka hōʻino ʻana i nā mea olakino kokoke.
- Hoʻoikaika radiation-modulated radiation therapy (IMRT): ʻO IMRT kahi ʻano o 3-dimensional (3-D) radiation radiation e hoʻohana nei i kahi kamepiula e hana i nā kiʻi o ka nui a me ke ʻano o ka tumo. ʻO nā kaola lahilahi o ka pāhawewe o nā ʻokoʻa ʻokoʻa (ikaika) e kuhikuhi ʻia i ka tumo mai nā kihi he nui.
- Volumetrical modulated arc therapy (VMAT): ʻo VMAT ke ʻano o ka radiation radiation 3-D e hoʻohana nei i kahi kamepiula e hana i nā kiʻi o ka nui a me ke ʻano o ka tumo. Holo ka mīkini radiation i kahi pōʻai a puni ka mea hoʻomanawanui i ka manawa o ka mālama ʻana a hoʻouna i nā kaola lahilahi o ka radiation o nā ʻano ʻokoʻa (ikaika) ma ka tumo. Lawe ʻia ka mālama ʻana me VMAT ma mua o ka mālama ʻana me IMRT.
- Hoʻoikaika kino kino Stereotactic: He ʻano radiation radiation kino ʻo Stereotactic. Hoʻohana ʻia nā pono kūikawā e hoʻonoho i ka mea maʻi ma ke kūlana like no kēlā me kēia hoʻomaʻamaʻa radiation. Hoʻokahi manawa i ka lā no kekahi mau lā, kuhi ka mīkini radiation i kahi ʻoi aku ka nui ma mua o ka maʻamau maʻamau o ka radiation ma ka tumo. Ma ka loaʻa ʻana o ka mea maʻi ma ke kūlana like no kēlā me kēia lapaʻau, ʻoi aku ka liʻiliʻi o ka hōʻino ʻana i nā mea olakino kokoke. Kapa ʻia kēia kaʻina hana ʻo stereotactic waho-kukuna radiation radiation a me stereotaxic radiation therapy.
- Hoʻomaʻo radiation radiation Proton: ʻo ka Proton-beam therapy kahi ʻano o ka ikehu kiʻekiʻe, ʻo radiation radiation waho. Hoʻopaʻa kahi mīkini radiation radiation i nā kahawai o nā protons (nā liʻiliʻi, ʻike ʻole ʻia, nā ʻikikikaʻi i hoʻopiʻi ʻia) i nā hunaola maʻi ʻino e pepehi iā lākou. ʻO kēia ʻano lapaʻau e hōʻemi i ka pohō o nā mea olakino kokoke.
- Hoʻohana ka radiation radiation i loko i kahi lāʻau radioactive i hoʻopaʻa ʻia i nā nila, nā hua, nā uea, a i ʻole nā catheters i kau pololei ʻia i loko a kokoke paha i ka maʻi ʻaʻai. Hoʻohana ʻia ia e mālama i ka maʻi ʻaʻai ma nā wahi e like me ka ʻōpua, ka puʻupuʻu, ka pūpū, ka maʻi huki, ka hānai, ka poʻo, a me ka ʻāʻī. Kāhea ʻia ʻo radiation radiation i loko o brachytherapy, radiation i loko, implant radiation, a i ʻole interstitial radiation therapy.
ʻO ke ʻano a me ka nui o ka radiation radiation a ke hāʻawi ʻia ia mea i ka makahiki o ke keiki, ke ʻano o ka rhabdomyosarcoma, kahi i hoʻomaka ai ke tumo, ehia mau tumo i koe ma hope o ke kaha ʻana, a inā he tumo i nā lymph node kokoke .
Hoʻohana pinepine ʻia ka radiation radiation e mālama i ka rhabdomyosarcoma kamaliʻi akā i kekahi mau ʻano hoʻohana ʻia ka radiation radiation i loko.
ʻO Chemotherapy
ʻO Chemotherapy kahi lāʻau lapaʻau maʻi maʻi e hoʻohana i nā lāʻau e hōʻoki i ka ulu ʻana o nā hunaola maʻi ʻaʻai, ma ka luku ʻana i nā hunaola a i ʻole ke kāpae ʻana iā lākou mai ka hoʻokaʻawale. Ke lawe ʻia ka chemotherapy e ka waha a i ʻole injected i loko o kahi aa koko a i ʻole nā mākala, komo nā lāʻau i ke kahe o ke koko a hiki ke kiʻi i nā hunaola maʻi ʻōpio i loko o ke kino (chemotherapy ʻōnaehana). Ke waiho pololei ʻia ka chemotherapy i loko o ka wai cerebrospinal, kahi hui, a i ʻole ke kino o ke kino e like me ka ʻōpū, ʻo nā lāʻau lapaʻau ka mea nui e hoʻopili i nā hunaola maʻi ʻaʻai i kēlā mau wahi (chemotherapy āpau).
Hāʻawi ʻia nō hoʻi ʻo Chemotherapy e hoʻoliʻiliʻi i ka tumo ma mua o ke kahakaha ʻana i mea e mālama ai i nā mea olakino hiki ke hiki. Kapa ʻia kēia ʻo neoadjuvant chemotherapy.
Pono kēlā me kēia keiki e mālama ʻia no ka rhabdomyosarcoma i ka chemotherapy ʻōnaehana e hoʻoliʻiliʻi i ka manawa e hoʻi hou ai ka maʻi ʻaʻa. ʻO ke ʻano o ka lāʻau anticancer, ka mahele lāʻau, a me ka helu o nā hana i hāʻawi ʻia e pili ana i ka loaʻa o ke kamepiula i kahi kūlana haʻahaʻa, waena waena, a i ʻole rhabdomyosarcoma kiʻekiʻe.
E ʻike i nā lāʻau i ʻae ʻia no Rhabdomyosarcoma no ka ʻike hou aku.
Ke hoʻāʻo ʻia nei nā ʻano lapaʻau hou i nā hoʻokolohua hoʻokolohua.
Hōʻike kēia ʻāpana hōʻuluʻulu manaʻo i nā mālama e hoʻopaʻa ʻia nei i nā hoʻokolohua hoʻokolohua. ʻAʻole paha ia e ʻōlelo i kēlā me kēia lapaʻau hou e hoʻopaʻa ʻia ana. Loaʻa nā ʻike e pili ana i nā hoʻokolohua hoʻokolohua mai ka pūnaewele NCI.
Immunotherapy
ʻO ka Immunotherapy kahi lapaʻau e hoʻohana i ka ʻōnaehana pale maʻi o ka mea maʻi e hakakā i ka maʻi ʻaʻai. Hoʻohana ʻia nā mea i hana ʻia e ke kino a i hana ʻia paha i kahi keʻena hoʻokolohua e hoʻonui, kuhikuhi, a hoʻihoʻi hou i nā pale kūlohelohe o ke kino i ka maʻi ʻaʻai. Kāhea ʻia kēia ʻano lapaʻau maʻi ʻaʻai a biologic therapy a i ʻole biotherapy.
Aia kekahi ʻano o ka immunotherapy:
- ʻO ka lāʻau lapaʻau lāʻau lapaʻau kahi lāʻau lapaʻau maʻi maʻi e hoʻohana i kahi mea a i ʻole hui o nā mea e hoʻonāukiuki ai i ka ʻōnaehana pale e ʻike ai i ka tumo a make loa Ke aʻo ʻia nei ka lāʻau hoʻomaʻamaʻa lāʻau e mālama i ka rhabdomyosarcoma metastatic.
- Hoʻohana ka lāʻau hoʻopalekana pale maʻi palekana i ka ʻōnaehana pale o ke kino e pepehi i nā hunaola maʻi ʻaʻai. Ke aʻo ʻia ʻelua ʻano o nā mea pale pale pale pale pale pale i ka mālama ʻana i ka rhabdomyosarcoma kamaliʻi i hoʻi mai ma hope o ka lapaʻau ʻana.
- ʻO CTLA-4 kahi protein i ka ʻili o nā hunaola T e kōkua ai e mālama i nā pane pale o ke kino i ka nānā ʻana. Ke hoʻopili aku ʻo CTLA-4 i kahi protein ʻē aʻe i kapa ʻia ʻo B7 ma ke kolamu maʻi ʻaʻai, kū ia i ka hunaola T mai ka luku ʻana i ka pūnaeho maʻi maʻi. Hoʻopili ka mea pāpālina CTLA-4 i CTLA-4 a ʻae i nā hunaola T e pepehi i nā hunaola maʻi ʻaʻai. ʻO Ipilimumab kahi ʻano o ka mea kāohi iā CTLA-4.
- ʻO PD-1 kahi protein i ka ʻili o nā hunaola T e kōkua ai i ka mālama ʻana i nā pane pale o ke kino. Ke hoʻopili aku ʻo PD-1 i kahi protein ʻē aʻe i kapa ʻia ʻo PDL-1 ma kahi hunaola maʻi ʻoki, paʻa ia i ke kele T mai ka luku ʻana i ka pūnaeho maʻi maʻi. Hoʻopili nā mea pale PD-1 i PDL-1 a ʻae i nā hunaola T e pepehi i nā hunaola maʻi ʻaʻai. ʻO Nivolumab a me pembrolizumab nā mea kāohi iā PD-1.
Pahuhopu kau ʻia
ʻO ka therapy target kahi ʻano lapaʻau e hoʻohana i nā lāʻau a i ʻole nā mea ʻē aʻe e hoʻouka aku i nā hunaola maʻi ʻaʻai. Hoʻohui pinepine nā therapies i hoʻomākaukau ʻia e hōʻemi i ka pōʻino i nā hunaola maʻamau ma mua o ka chemotherapy a i ʻole ka radiation. Aia kekahi mau ʻano o ka hoʻomōhala hoʻomāka ʻia.
- Hoʻopau nā mea kāohi mTOR i ka protein i kōkua i nā hunaola e māhele a ola. ʻO Sirolimus kahi ʻano mTOR mea kāohi lāʻau lapaʻau e hoʻopaʻa ʻia ana i ka mālama ʻana i ka rhabdomyosarcoma hou.
- ʻO nā mea kāohi ʻo Tyrosine kinase nā lāʻau liʻiliʻi liʻiliʻi e hele ma waena o ka membrane pūnaewele a hana i loko o nā hunaola maʻi ʻaukā e ālai i nā hōʻailona e pono e ulu a hoʻokaʻawale nā hunaola maʻi ʻino. ʻO ka MK-1775 a me ka cabozantinib-s-malate he mau mea hoʻopale tyrosine kinase ke aʻo ʻia i ka mālama ʻana i ka rhabdomyosarcoma hou.
Makemake paha nā mea maʻi e noʻonoʻo e pili ana i ka hoʻokolokolo ʻana.
No kekahi mau mea maʻi, ke komo nei i ka hoʻokolohua hoʻokolohua ke koho lapaʻau maikaʻi loa paha. ʻO nā hoʻokolohua hoʻokolohua kahi ʻāpana o ka noiʻi ʻana o ka maʻi ʻaʻai. Hana ʻia nā hoʻokolohua hoʻokolohua e ʻike inā palekana a maikaʻi a maikaʻi paha nā hoʻomaʻamaʻa maʻi ʻaʻai ma mua o ka maʻamau maʻamau.
ʻO ka hapa nui o nā hana maʻamau no ka maʻi ʻaʻai i kau ʻia ma nā hoʻokolohua hoʻokolohua mua. ʻO nā mea maʻi i komo i ka hoʻokolokolo hoʻokolohua hiki ke loaʻa i ka lāʻau maʻamau a i ʻole i waena o nā mea mua i loaʻa kahi lāʻau hou.
ʻO nā mea maʻi i komo i nā hoʻokolohua hoʻokolohua kōkua pū kekahi i ka hoʻomaikaʻi ʻana i ke ʻano o ka mālama ʻana i ka maʻi ʻaʻai i ka wā e hiki mai ana. ʻOiai ʻaʻole nā alakaʻi hoʻokolohua e alakaʻi i nā hoʻoponopono hou maikaʻi, pane pinepine lākou i nā nīnau nui a kōkua i ka neʻe i mua o ka noiʻi.
Hiki i nā mea maʻi ke komo i nā hoʻokolohua hoʻokolohua ma mua, i ka wā, a ma hope paha o ka hoʻomaka ʻana i kā lākou mālama maʻi ʻaʻai.
Hoʻopili wale kekahi mau hoʻokolohua hoʻokolohua i nā mea maʻi i loaʻa ʻole ka lapaʻau. ʻO nā hoʻokolohua ʻē aʻe e hōʻoia i nā mālama ʻana no ka poʻe maʻi i loaʻa ʻole ka maikaʻi o ka maʻi ʻaʻai. Aia kekahi mau hoʻokolohua hoʻokolohua e hoʻāʻo i nā ala hou e hōʻoki i ka maʻi ʻaʻai mai ka hoʻi hou ʻana (hoʻi ʻana) a hōʻemi paha i nā hopena o ka mālama ʻana i ka maʻi ʻaʻai.
Ke mālama ʻia nei nā hoʻokolohua hoʻokolohua ma nā wahi he nui o ka ʻāina. Hiki ke ʻike ʻia ka ʻike e pili ana i nā hoʻokolohua hoʻokolohua e kākoʻo ʻia e NCI ma ka pūnaewele ʻimi noiʻi hoʻokolohua a NCI. Hiki ke loaʻa nā hoʻokolohua hoʻokolohua i kākoʻo ʻia e nā hui ʻē aʻe ma ka pūnaewele ClinicalTrials.gov.
Pono paha nā hoʻokolohua ukali.
ʻO kekahi o nā hoʻokolohua i hana ʻia e hōʻoia i ka maʻi ʻaʻai a i ʻole e ʻike i ke kahua o ka maʻi ʻaʻaʻa e hana hou ʻia paha. E hana hou ʻia kekahi mau hōʻike i mea e ʻike ai i ka maikaʻi o ka mālama ʻana. Hoʻoholo ʻia nā hoʻoholo e pili ana inā e hoʻomau, hoʻololi, a kū paha i ka lāʻau ʻana ma nā hopena o kēia mau hoʻāʻo.
E hoʻomau ʻia kekahi o nā hoʻokolohua mai kēlā me kēia manawa ma hope o ka pau ʻana o ka lāʻau. Hiki i nā hopena o kēia mau hoʻāʻo ke hōʻike inā ua loli ke ʻano o kāu keiki a i ʻole ua hoʻi hou ke kanesa. Kapa ʻia kēia mau hoʻāʻo i kekahi manawa nā hoʻokolohua ukali a i ʻole nā loiloi.
Nā koho lapaʻau no Rhabdomyosarcoma kamaliʻi
Ma keia Pauku
- ʻO Rhabdomyosarcoma kamaliʻi i hoʻomaʻamaʻa ʻole ʻia ma mua
- ʻO Refractory a i ʻole Recurrent Childhood Rhabdomyosarcoma
No ka ʻike e pili ana i nā lāʻau i helu ʻia ma lalo, e ʻike i ka ʻaoʻao Overtion Option Overview.
ʻO Rhabdomyosarcoma kamaliʻi i hoʻomaʻamaʻa ʻole ʻia ma mua
ʻO ka mālama ʻana i ka rhabdomyosarcoma kamaliʻi pinepine me ka ʻoki ʻana, ka radiation radiation, a me ka chemotherapy. Hāʻawi ʻia ke kauoha e hāʻawi ʻia i kēia mau ʻano hana e pili ana i kahi i hoʻomaka ai ke tumo, ka nui o ka tumo, ke ʻano o ka puʻukū, a inā paha ua palahalaha ka tumo i nā pūnana lymph a i ʻole nā ʻāpana ʻē aʻe o ke kino E ʻike i ka ʻāpana Overtion Option Overview o kēia hōʻuluʻulu manaʻo no ka ʻike hou aku e pili ana i ke kahakaha, radiation radiation, a me ka chemotherapy i hoʻohana ʻia e mālama ai i nā keiki me ka rhabdomyosarcoma.
Rhabdomyosarcoma o ka lolo a me ke poʻo a me ka ʻāʻī
- No nā tumors o ka lolo: Hoʻokomo ʻia ka mālama ʻana i kahi ʻoki e wehe i ka tumo, radiation radiation, a me chemotherapy.
- No nā tumors o ke poʻo a me ka ʻāʻī i loko a i ʻole ka maka o ka maka: Hoʻokomo ʻia ka hoʻomaʻamaʻa me chemotherapy a me radiation therapy. Inā kū ka tumo a hoʻi mai paha ma hope o ka mālama ʻana me chemotherapy a me radiation therapy, ʻoki ʻia e wehe i ka maka a me kekahi mau ʻū a puni ka maka e pono ai.
- No nā tumors o ke poʻo a me ka ʻāʻī e kokoke ana i ka pepeiao, ihu, sinus, a i ʻole ke kumu o ka iwi poʻo akā ʻaʻole i loko a i ʻole ka maka o ka maka: Hiki i ka mālama ʻana ke hoʻopili i ka radiation radiation a me ka chemotherapy.
- No nā tumors o ke poʻo a me ka ʻāʻī ʻaʻole i loko a kokoke paha i ka maka a ʻaʻole kokoke i ka pepeiao, ihu, sinus, a i ʻole kumu o ka iwi poʻo: Hoʻokomo ʻia ka hoʻomaʻamaʻa me chemotherapy, radiation therapy, a me ke kaha ʻana e hemo ai ka tumo.
- No nā tumors o ke poʻo a me ka ʻāʻī ʻaʻole hiki ke hoʻoneʻe ʻia e ke ʻokiʻoki: Hiki i ka hoʻomaʻamaʻa ke komo pū me ka chemotherapy a me ka radiation therapy me ka stereotactic body radiation therapy.
- No nā tumors o ka larynx (pahu leo): Hoʻokomo ʻia ka hoʻomaʻamaʻa me chemotherapy a me radiation therapy. ʻAʻole hana pinepine ʻia ke ʻoki ʻana e wehe i ka larynx, i hōʻeha ʻole ʻia ka leo.
Rhabdomyosarcoma o nā lima a me nā wāwae
- Chemotherapy ukali ʻia me ke ʻoki e wehe i ka tumo. Inā ʻaʻole i hemo loa ka tumo, hana ʻoki ʻia ka ʻoki ʻelua e wehe i ka tumo. Hiki ke hāʻawi ʻia i ka radiation radiation.
- No nā tumors o ka lima a me ka wāwae paha, hāʻawi ʻia ka radiation therapy a me ka chemotherapy. ʻAʻole hiki ke hemo ʻia ka tumo no ka mea e hoʻopili ana i ka hana o ka lima a me ka wāwae.
- Lymph node dissection (wehe ʻia hoʻokahi a ʻoi aku mau lymph node a nānā ʻia kahi laʻana o nā kiko ma lalo o kahi microscope no nā ʻōuli o ke kanesa).
- No nā tumors i nā lima, lawe ʻia nā lymph node kokoke i ka tumo a ma kahi o ka ʻāpana lima.
- No nā puʻupuʻu i nā wāwae, hoʻoneʻe ʻia nā lymph node kokoke i ka tumo a ma ka ʻeha.
Rhabdomyosarcoma o ka umauma, ʻōpū, a i ʻole pelvis
- No nā tumors i ka umauma a i ʻole ka ʻōpū (me ka paia o ka umauma a i ʻole ka paia ʻōpū): ʻO ke ʻoki kino (ākea kahi kūloko). Inā nui ka tumo, hāʻawi ʻia ka chemotherapy a me ka radiation therapy e hoʻoliʻiliʻi i ka tumo ma mua o ke kahakaha ʻana.
- No nā tumors o ka pelvis: hiki ke hana ʻia i kahi ʻoki kino (excision ākea ākea). Inā nui ka tumo, hāʻawi ʻia ka chemotherapy e hoʻoliʻiliʻi i ka tumo ma mua o ke kahakaha ʻana. Hāʻawi ʻia ka radiation radiation ma hope o ke kaha ʻana.
- No nā tumors o ka diaphragm: ukali ʻia kahi biopsy o ka tumo e ka chemotherapy a me ka radiation therapy e hoʻoliʻiliʻi ai i ka tumo. Hana ʻia ke kaha ma hope e wehe i nā hunaola maʻi ʻea i koe.
- No nā tumors o ka gallbladder a i ʻole nā dile bile: ukali ʻia kahi biopsy o ka tumo e chemotherapy a me radiation therapy.
- No nā tumors o nā mākala a i ʻole nāʻaʻa puni ka anus a ma waena o ka puʻupuʻu a me ka anus a i ʻole ka scrotum a me ka anus.
Rhabdomyosarcoma o ka puʻupaʻa
- No nā tumors o ka puʻupaʻa: Ke ʻoki ʻana e wehe i ka nui o ka tumo i hiki. Hāʻawi ʻia kahi Chemotherapy a me radiation therapy.
Rhabdomyosarcoma o ka maʻi ʻaʻai a prostate paha
- No nā tumors aia wale nō ma ka piko o ka bladder: ua hana ʻia ke ʻoki (ākoki kūloko ākea).
- No nā tumors o ka prostate a i ʻole bladder (ʻē aʻe ma mua o ka piko o ka maʻi ʻaʻai):
- Hāʻawi mua ʻia ʻo Chemotherapy a me radiation therapy e hoʻoliʻiliʻi i ka tumo. Inā hoʻomau nā hunaola maʻi ʻaʻai ma hope o ka chemotherapy a me ka radiation therapy, hemo aku ka tumo ma ke ʻoki ʻana. Hiki i ke kīʻaha ke kāpae aku i ka prostate, kahi ʻāpana o ka puhā, a i ʻole pelvic exenteration me ka hemo ʻole o ka pololei. (Pili paha kēia i ka hemo ʻana o ke kolona lalo a me ka ʻai. I loko o nā kaikamahine, hoʻoneʻe ʻia ka cervix, nā ʻōpū, nā ovaries, a me nā lymph kokoke.
- Hāʻawi mua ʻia ʻo Chemotherapy e hoʻoliʻiliʻi i ka tumo. ʻO ke kīʻaha e hemo ai i ka tumo, akā ʻaʻole ka bladder a i ʻole ka prostate. Hiki ke hāʻawi ʻia i loko a i waho paha ka radiation radiation ma hope o ke kaha ʻana.
- ʻO ke ʻoki kino e hemo ai i ka tumo, ʻaʻole naʻe ka maʻi ʻaʻai a prostate paha. Hāʻawi ʻia ka radiation radiation ma hope o ke kaha ʻana.
Rhabdomyosarcoma o ka wahi kokoke i nā testicle
- ʻO ke keʻoki e wehe i ka testicle a me ke kaula spermatic. Hiki ke nānā ʻia nā lymph nodes ma ka hope o ka ʻōpū no ka maʻi ʻaʻai, keu hoʻi inā he nui nā lymph a i ʻole he 10 mau makahiki a ʻoi paha ke keiki.
- Hāʻawi ʻia ka radiation radiation inā ʻaʻole hiki ke hoʻopau loa ʻia ka tumo e ke ʻoki.
Rhabdomyosarcoma o ka puʻupuʻu, pūpū, uterus, cervix, a i ʻole ovary
- No nā tumors o ka puʻupuʻu a me ka maʻi puʻupaʻa: hiki i ka hoʻomaʻamaʻa ke komo pū me ka chemotherapy a ukali ʻia e ke ʻoki e wehe i ka tumo. Hiki ke hāʻawi ʻia i loko a i waho paha ka radiation radiation ma hope o ke kaha ʻana.
- No nā tumors o ka kōpū: Hiki i ke olakino ke komo pū me ka chemotherapy me a i ʻole me ka ʻole o radiation radiation. I kekahi manawa pono paha ke ʻoki e wehe i nā hunaola maʻi ʻē i koe.
- No nā tumors o ka cervix: hiki i ka mālama ʻana ke komo pū me ka chemotherapy a ukali ʻia e ke ʻoki ʻana e wehe i nā tumo i koe.
- No nā tumors o ka ovary: Hiki i ka hoʻomaʻamaʻa ke komo pū me ka chemotherapy a ukali ʻia e ke ʻoki e wehe i nā tumo i koe.
Rhabdomyosarcoma Metastatic
ʻO ka mālama ʻana, e like me chemotherapy, radiation radiation, a i ʻole ke ʻoki ʻana e hemo ai ka tumo, hāʻawi ʻia i ka pūnaewele kahi i hoʻokumu mua ʻia ai ka tumo. Inā ua pālahalaha ka maʻi ʻaʻai i ka lolo, ka iwi kuamoo, a i ʻole nā akemāmā, hiki ke hāʻawi ʻia ka radiation therapy i nā pūnaewele kahi i laha ai ka maʻi ʻaʻai.
Ke aʻo ʻia nei ka mālama ʻana no ka rhabdomyosarcoma metastatic:
- ʻO kahi hoʻokolohua hoʻokolohua o ka immunotherapy (vaccine therapy).
E hoʻohana i kā mākou ʻimi hoʻokolohua hoʻokolohua e ʻike i nā hoʻokolohua hoʻokolohua maʻi maʻi i kākoʻo ʻia e NCI e ʻae nei i nā mea maʻi. Hiki iā ʻoe ke ʻimi i nā hoʻāʻo e pili ana i ke ʻano o ka maʻi ʻaʻai, ka makahiki o ka mea hoʻomanawanui, a kahi e hana ʻia ai nā hoʻokolokolo. Loaʻa nā ʻike laulā e pili ana i nā hoʻokolohua hoʻokolohua.
ʻO Refractory a i ʻole Recurrent Childhood Rhabdomyosarcoma
ʻO nā koho lapaʻau no ka refactory a i ʻole hoʻi hou o ka rhabdomyosarcoma kamaliʻi e pili ana i nā kumu he nui, e like me kahi i hoʻi i ke kino o ka maʻi ʻaʻai, he aha ke ʻano o ka mālama ʻana a ke keiki ma mua, a me nā pono o ke keiki.
Hoʻomaʻamaʻa paha i ka rhabdomyosarcoma refactory a i ʻole hoʻi i hoʻokahi o nā mea hou aʻe:
- ʻOki kino.
- Lapaʻau hoʻomākala.
- ʻO Chemotherapy.
- ʻO kahi hoʻokolohua hoʻokolohua o ka therapy i hoʻomāka ʻia a i ʻole immunotherapy (sirolimus, ipilimumab, nivolumab, a i ʻole pembrolizumab).
- ʻO kahi hoʻokolohua hoʻokolohua o ka lāʻau hoʻomoʻa ʻia me kahi mea kāohi inhibitor tyrosine (MK-1775 a i ʻole cabozantinib-s-malate) a me ka chemotherapy.
- ʻO kahi hoʻokolohua hoʻokolohua e nānā i kahi laʻana o ka tumo o ka mea maʻi no kekahi ʻano loli. ʻO ke ʻano o ka hoʻomālama ʻia e hāʻawi ʻia i ka mea maʻi e pili ana i ka ʻano o ka loli.
E hoʻohana i kā mākou ʻimi hoʻokolohua hoʻokolohua e ʻike i nā hoʻokolohua hoʻokolohua maʻi maʻi i kākoʻo ʻia e NCI e ʻae nei i nā mea maʻi. Hiki iā ʻoe ke ʻimi i nā hoʻāʻo e pili ana i ke ʻano o ka maʻi ʻaʻai, ka makahiki o ka mea hoʻomanawanui, a kahi e hana ʻia ai nā hoʻokolokolo. Loaʻa nā ʻike laulā e pili ana i nā hoʻokolohua hoʻokolohua.
E aʻo hou e pili ana i ke kamaliʻi Rhabdomyosarcoma
No ka ʻike hou aku mai ka National Cancer Institute e pili ana i ka rhabdomyosarcoma kamaliʻi, e ʻike i ka mea aʻe:
- ʻAoʻao Home Tissue Sarcoma Palapala
- Computers Tomography (CT) Scans a me ka maʻi ʻaʻai
- Ua ʻae ʻia nā lāʻau no Rhabdomyosarcoma
- ʻO nā Therapy Cancer i kau ʻia
No ka ʻike hou aku i ka maʻi ʻaʻai kamaliʻi a me nā kumuwaiwai maʻi ʻaʻai ʻē aʻe, e ʻike i ka mea aʻe:
- E pili ana i ka maʻi ʻaʻai
- Nā maʻi ʻōpio
- Huli ʻo Cure no ka hōʻole ʻana i nā maʻi ʻaʻai keiki
- Nā hopena hope loa o ka mālama ʻana no ka maʻi ʻaʻai kamaliʻi
- ʻO nā ʻōpio a me nā ʻōpio me ka maʻi ʻaʻai
- Nā keiki me ka maʻi ʻaʻai: He alakaʻi no nā mākua
- Ka maʻi ʻaʻai ma nā keiki a me nā ʻōpio
- Ke hoʻokū nei
- Ke kāohi nei i ka maʻi ʻaʻai
- Nā nīnau e nīnau ai i kāu kauka e pili ana i ka maʻi ʻaʻai
- No nā mea ola a me nā mea mālama
