Types/myeloproliferative/patient/myelodysplastic-treatment-pdq
Nā ʻikepili i loko
Hoʻomaʻamaʻa Myelodysplastic Syndromes (®) - Mana Mana Manaʻo
ʻO ka ʻike pili e pili ana i ka Myelodysplastic Syndrome
NA MANA KUNI
- ʻO ka myelodysplastic syndrome kahi hui o nā maʻi ʻaʻai ma kahi o nā kō ʻole o ke kō ʻole i ka momona o ka iwi i oʻo a lilo i nā hunaola olakino maikaʻi.
- Kuhi ʻia nā ʻano like ʻole o ka myelodysplastic syndrome ma muli o kekahi mau loli i nā huna koko a me ka iwi iwi.
- ʻO ka makahiki a me ka mālama ʻana i hala me chemotherapy a i ʻole radiation therapy e hoʻopili i ka makaʻu o ka myelodysplastic syndrome.
- ʻO nā hōʻailona a me nā ʻōuli o ka myelodysplastic maʻi pū me ka liʻiliʻi o ka hanu a me ka luhi.
- Hoʻohana ʻia nā hoʻāʻo e nānā i ke koko a me ka iwi o ka iwi e ʻike (loaʻa) a hōʻoia i nā syndrome myelodysplastic.
- Pili kekahi mau mea i ka wānana a me nā koho lapaʻau.
ʻO ka myelodysplastic syndrome kahi hui o nā maʻi ʻaʻai ma kahi o nā kō ʻole o ke kō ʻole i ka momona o ka iwi i oʻo a lilo i nā hunaola olakino maikaʻi.
I loko o kahi kanaka olakino, hana ka iwi o ka iwi i nā hunaola koko (ʻaʻa ʻole) e lilo i mau puʻupuʻu mākua ma mua o ka manawa.
Hiki i ke kinipōpō koko ke lilo i cell cell lymphoid a i ʻole ka cell myeloid stem cell. Lilo ke kinipōpō limapiʻi i keʻena keokeo. E lilo i kahi cell myeloid stem i hoʻokahi o ʻekolu mau ʻano o nā hunaola makua oʻo:
- ʻO nā hunaola ʻulaʻula e lawe i ka oxygen a me nā mea ʻē aʻe i nā kinona āpau o ke kino.
- ʻO nā pāpale e hana ana i ke kahe o ke koko e hōʻoki i ke kahe ʻana o ke kahe.
- ʻO nā hunaola keʻokeʻo e hakakā i ka maʻi a me ka maʻi.
I ka mea hoʻomanawanui me ka myelodysplastic Syndrome, ʻaʻole e lilo nā hunaola koko (nā ʻikena makua ʻole) i mau hunaola ʻulaʻula makua, nā hunaola keʻokeʻo, a i ʻole nā platelet i ka iwi iwi. ʻAʻole hana kēia mau hunaola koko makua ʻole, i kapa ʻia he blasts, i ke ala e pono ai a make i ka iwi iwi a i ʻole ma hope koke iho o ka hele ʻana i loko o ke koko. Haʻalele kēia i ka lumi liʻiliʻi no nā hunaola keokeo olakino, nā hunaola ʻulaʻula, a me nā platelet e hana i ka iwi iwi. Ke liʻiliʻi nā kaola olakino olakino, maʻi, anemia, a maʻalahi paha ke kahe ʻana.
Kuhi ʻia nā ʻano like ʻole o ka myelodysplastic syndrome ma muli o kekahi mau loli i nā huna koko a me ka iwi iwi.
- Anemia Refractory: Nui a liʻiliʻi nā hunaola ʻulaʻula i ke koko a he anemia ka mea maʻi. ʻO ka helu o nā hunaola keʻokeʻo a me nā platelet ka mea maʻamau.
- ʻO ka anemia Refractory me nā sideroblast ring: Nui a liʻiliʻi nā ʻulaʻula i ke koko a he anemia ka mea maʻi. Nui ka hao o nā hunaola ʻulaʻula i loko o ka huna. ʻO ka helu o nā hunaola keʻokeʻo a me nā platelet ka mea maʻamau.
- ʻO ka anemia Refractory me nā blasts he nui : Nui a liʻiliʻi nā ʻulaʻula i ke koko a he anemia ka mea maʻi. ʻElima pākēneka a 19% o nā hunaola i loko o ka iwi iwi ka hā. Aia kekahi mau hoʻololi paha i nā hunaola keʻokeʻo a me nā platelet. Hiki ke holomua i ka anemia repractory me nā pahū nui i ka leukemia myeloid koʻikoʻi (AML). E ʻike i ka hōʻuluʻulu makua Acute Myeloid Leukemia hōʻuluʻulu manaʻo no ka ʻike hou aku.
- ʻO ka cytopenia Refractory me ka displasia multilineage: Aia kekahi o nā ʻano ʻelua o ke kahe o ke koko (nā hunaola ʻulaʻula, nā platelets, a i ʻole nā aʻa koko keʻokeʻo). Ma lalo o 5% o nā hunaola i loko o ka iwi iwi ka puhi a ʻoi aku ka liʻiliʻi ma mua o 1% o nā hunaola i ke koko. Inā hoʻopili ʻia nā hunaola koko ʻula, loaʻa paha iā lākou ka hao keu. E holomua paha ka cytopenia refractory i ka leukemia myeloid nui (AML).
- ʻO ka cytopenia Refractory me ka displasia unilineage: Aia kekahi o kekahi ʻano o ke kele koko (nā hunaola ʻulaʻula, nā platelets, a i ʻole nā aʻa koko keʻokeʻo). Aia nā hoʻololi i 10% a ʻoi aku paha o ʻelua ʻano ʻē aʻe o nā hunaola koko. Ma lalo o 5% o nā hunaola i loko o ka iwi iwi ka puhi a ʻoi aku ka liʻiliʻi ma mua o 1% o nā hunaola i ke koko.
- Unclassifiable myelodysplastic Syndrome: ʻO ka helu o nā puhi i ka iwi iwi a me ke koko he maʻamau ia, a ʻo ka maʻi ʻaʻole kekahi o nā syndrome myelodysplastic ʻē aʻe.
- Myelodysplastic Syndrome pili i kahi kaʻawale del (5q) chromosome abnormalities: Nui a liʻiliʻi nā ʻulaʻula i ke koko a he anemia ka mea maʻi. Ma lalo o 5% o nā hunaola i loko o ka iwi iwi a me ke koko he pahū. Aia kekahi hoʻololi kikoʻī i ka chromosome.
- ʻO ka leukemia myelomonosittic mau loa (CMML): E ʻike i ka hōʻuluʻulu ma Myelodysplastic / Myeloproliferative Neoplasms i hoʻoponopono ʻia no ka ʻike hou aku.
ʻO ka makahiki a me ka mālama ʻana i hala me chemotherapy a i ʻole radiation therapy e hoʻopili i ka makaʻu o ka myelodysplastic syndrome.
ʻO nā mea āpau e hoʻonui i kou makaʻu i ka loaʻa ʻana i kahi maʻi i kapa ʻia he kumu weliweli. ʻO ka loaʻa ʻana o kahi mea pilikia ʻaʻole ia he kumu e loaʻa ai ʻoe i ka maʻi. ʻaʻohe o nā kumu pilikia ʻaʻole ia he kumu ʻaʻole ʻoe e loaʻa i kahi maʻi. E kamaʻilio me kāu kauka inā manaʻo ʻoe ua makaʻu paha ʻoe. ʻO nā kumu pilikia no ka myelodysplastic syndromes e hoʻopili ʻia i kēia mau mea:
- ʻO ka mālama i hala me chemotherapy a i ʻole radiation therapy no ka maʻi ʻaʻai.
- Ke hōʻike ʻia nei i kekahi mau kemika, e laʻa me ka uahi paka, nā pesticides, nā mea momona, a me nā mea hoʻoheheʻe e like me benzene.
- Ke hōʻike ʻia nei i nā metala kaumaha, e like me ka mercury a kēpau paha.
ʻO ke kumu o ka myelodysplastic syndrome i ka hapanui o nā mea maʻi i ʻike ʻole ʻia.
ʻO nā hōʻailona a me nā ʻōuli o ka myelodysplastic maʻi pū me ka liʻiliʻi o ka hanu a me ka luhi.
ʻAʻole pinepine nā syndrome Myelodysplastic i nā hōʻailona a i ʻole nā hōʻailona mua. ʻIke ʻia paha lākou i kahi hoʻokolohua koko maʻamau. Hoʻokumu ʻia nā hōʻailona a me nā ʻōuli e myelodysplastic syndromes a i ʻole nā ʻano ʻē aʻe. E hōʻoia me kāu kauka inā loaʻa iā ʻoe kekahi o kēia mau mea:
- Pokole o ka hanu.
- Nawaliwali a ʻano luhi paha.
- Loaʻa ka ʻili i ʻoi aku ka pale ma mua o ka maʻamau.
- Pākuʻi maʻalahi a hoʻokahe paha.
- Petechiae (pālahalaha, kiko kiko ma lalo o ka ʻili i hoʻokumu ʻia e ke kahe ʻana o ke kahe).
Hoʻohana ʻia nā hoʻāʻo e nānā i ke koko a me ka iwi o ka iwi e ʻike (loaʻa) a hōʻoia i nā syndrome myelodysplastic.
Hiki ke hoʻohana ʻia nā hoʻāʻo a me nā kaʻina hana aʻe:
- ʻO ka hoʻāʻo kino a me ka mōʻaukala: kahi hōʻike o ke kino e nānā i nā hōʻailona laulā o ke olakino, e like me ka nānā ʻana i nā hōʻailona o ka maʻi, e like me nā puʻupuʻu a i ʻole nā mea ʻē aʻe e ʻano ʻē. E lawe ʻia kahi moʻolelo o nā ʻano olakino o ka mea maʻi a me nā maʻi i hala a me nā mālama ʻana.
- Helu piha ke koko (CBC) me ka ʻokoʻa: kahi kaʻina hana e huki ʻia ai kahi hāpana o ke koko a nānā ʻia no kēia mau mea:
ʻO ka helu o nā hunaola ʻulaʻula a me nā platelet.
- ʻO ka helu a me ke ʻano o nā hunaola keokeo.
- ʻO ka nui o ka hemoglobin (ka protein i hāpai i ka oxygen) i loko o nā hunaola ʻulaʻula.
- ʻO ka ʻāpana o ka hāpana koko i hana ʻia i nā hunaola ʻulaʻula.
- Hoʻopili ke koko peripheral: kahi hana e nānā ai kahi hāpana o ke koko no nā loli i ka helu, ʻano, kinona, a me ka nui o nā hunaola a no ka nui o ka hao i nā hunaola ʻulaʻula.
- Nānā Cytogenetic: kahi hoʻokolohua hoʻokolohua kahi e helu ai nā chromosome o nā hunaola i kahi hāpana o ka iwi iwi a i ʻole ke koko no nā loli, e like me ka haki, nalowale, hoʻoponopono hou ʻia, a i ʻole nā chromosome keu. ʻO nā loli i kekahi mau chromosome he hōʻailona ia o ka maʻi ʻaʻai. Hoʻohana ʻia ka hoʻoponopono Cytogenetic e kōkua i ke kuhi ʻana i ka maʻi ʻaʻai, e hoʻolālā i ka lāʻau ʻana, a i ʻole e ʻike i ke ʻano o ka maikaʻi o ka mālama ʻana.
- Nā aʻo kemika koko: kahi hana e nānā ʻia ai kahi laʻana koko e ana i ka nui o kekahi mau mea, e like me ka wikamina B12 a me folate, i hoʻokuʻu ʻia i loko o ke koko e nā mea a me nā mea i loko o ke kino. ʻO kahi mea maʻamau (ʻoi aʻe a i ʻole haʻahaʻa ma mua o ka maʻamau) o kahi mea hiki ke lilo i hōʻailona o ka maʻi.
- ʻO ka ʻiʻo o ka iwi iwi a me ka biopsy: Ka hemo ʻana o ka iwi iwi, ke koko, a me kahi ʻāpana o ka iwi ma ka hoʻokomo ʻana i kahi kui kolo i loko o ka hipbone a i ʻole ka umauma. ʻIke kahi pathologist i ka momona o ka iwi, ke koko, a me ka iwi ma lalo o kahi microscope e nānā no nā hunaola ʻokoʻa.
E hana ʻia paha nā hoʻokolohua aʻe ma ka laʻana o nā kiko i lawe ʻia.
- Immunocytochemistry: kahi hoʻokolohua hoʻokolohua e hoʻohana ai i nā anti -antibodies e nānā ai no kekahi antigens (markers) i kahi laʻana o ka iwi iwi o ka mea maʻi. Hoʻopili pinepine ʻia nā mea ʻino i kekahi enzyme a i ʻole ka waihoʻoluʻu fluorescent. Ma hope o ka hoʻopili ʻana o nā mea ʻume i ka antigen i ka laʻana o nā hunaola o ka hoʻomanawanui, e hoʻoulu ʻia ka enzyme a i ʻole ke kala, a laila ʻike ʻia ka antigen ma lalo o kahi microscope. Hoʻohana ʻia kēia ʻano hoʻāʻo e kōkua i ke kuhi ʻana i ka maʻi ʻaʻai a me ka haʻi ʻana i ka ʻokoʻa ma waena o nā syndrome myelodysplastic, leukemia, a me nā kūlana ʻē aʻe.
- Immunophenotyping: kahi hoʻokolohua hoʻokolohua e hoʻohana ai i nā mea ʻino e ʻike ai i nā hunaola maʻi ʻaʻai e pili ana i nā ʻano antigens a i ʻole nā māka ma ka ʻili o nā hunaola. Hoʻohana ʻia kēia hōʻike e kōkua i ke kuhi ʻana i nā ʻano maʻi leukemia a me nā maʻi koko ʻē aʻe.
- Kahe uila ʻili pūnaewele. Hoʻopili ʻia nā hunaola mai kahi hāpana o ke koko o ka mea maʻi, ka iwi o ka iwi, a i ʻole nā mea ʻē aʻe me ka pena wai fluorescent, waiho ʻia i loko o kahi wai, a laila hele kekahi i hoʻokahi manawa i ke kaola o ke kukui. Hoʻokumu ʻia nā hopena o ka hoʻāʻo e pili ana i ka hopena o nā hunaola i hoʻohuehue ʻia me ka pena fluorescent i ke kaola o ke kukui. Hoʻohana ʻia kēia hoʻokolohua e kōkua i ke kuhi a mālama ʻana i kekahi ʻano o nā maʻi ʻaʻai, e like me leukemia a me lymphoma.
- FISH (fluorescence in situ hybridization): kahi hoʻokolohua hoʻokolohua i hoʻohana ʻia e nānā a helu i nā gen a i ʻole nā chromosome i nā pūnaewele a me nā aʻa. Hana ʻia nā ʻāpana o ka DNA i loaʻa nā waihoʻoluʻu fluorescent i loko o ke keʻena hoʻokolohua a hoʻohui ʻia i kahi laʻana o nā hunaola a me nā aʻa o ka mea maʻi. Ke hoʻopili aku kēia mau ʻāpana DNA i kala ʻia i kekahi mau ʻāpana a i ʻole nā wahi o chromosome i loko o ka hāpana, hoʻomālamalama lākou ke nānā ʻia ma lalo o kahi microscope fluorescent. Hoʻohana ʻia ka hōʻike FISH e kōkua i ke kuhi ʻana i ka maʻi ʻaʻai a kōkua i ka hoʻolālā ʻana i ka lāʻau.
Pili kekahi mau mea i ka wānana a me nā koho lapaʻau.
ʻO ka wānana (loaʻa o ke ola) a me nā koho lapaʻau e pili i kēia:
- ʻO ka helu o nā huna huna i loko o ka iwi iwi.
- Inā hopena a hoʻokahi a ʻoi paha o nā ʻano koko.
- Inā he mau hōʻailona a hōʻailona paha ka mea maʻi o ka anemia, ke kahe ʻana o ke koko, a i ʻole ka maʻi.
- Inā loaʻa i ka mea maʻi kahi haʻahaʻa a kiʻekiʻe paha o ka leukemia.
- Hoʻololi kekahi i nā chromosome.
- ʻO ka myelodysplastic maʻi i hana ma hope o chemotherapy a i ʻole radiation therapy no ka maʻi ʻaʻai.
- ʻO ka makahiki a me ke olakino olakino o ka mea maʻi.
Laulā Manaʻo Option Oponopono
NA MANA KUNI
- Aia nā ʻano lapaʻau like ʻole no nā mea maʻi me nā syndrome myelodysplastic.
- ʻO ka mālama ʻana no ka myelodysplastic syndrome e komo pū me ka mālama kōkua, ka lāʻau lapaʻau, a me ka transplantation cell stem.
- Hoʻohana ʻia ʻekolu ʻano o ka mālama maʻamau.
- Mālama kākoʻo
- Laʻau lāʻau
- ʻO Chemotherapy me ka transplant cell stem
- Ke hoʻāʻo ʻia nei nā ʻano lapaʻau hou i nā hoʻokolohua hoʻokolohua.
- ʻO ka mālama ʻana no ka myelodysplastic syndrome ke kumu i nā hopena ʻaoʻao.
- Makemake paha nā mea maʻi e noʻonoʻo e pili ana i ka hoʻokolokolo ʻana.
- Hiki i nā mea maʻi ke komo i nā hoʻokolohua hoʻokolohua ma mua, i ka wā, a ma hope paha o ka hoʻomaka ʻana i kā lākou lapaʻau.
- Pono paha nā hoʻokolohua ukali.
Aia nā ʻano lapaʻau like ʻole no nā mea maʻi me nā syndrome myelodysplastic.
Loaʻa nā ʻano lapaʻau like ʻole no nā mea maʻi me ka myelodysplastic syndrome. Kūlana maʻamau kekahi mau hōʻailona (ʻo ka lāʻau i hoʻohana ʻia i kēia manawa), a ʻo kekahi e hoʻāʻo ʻia nei i nā hoʻokolohua hoʻokolohua. ʻO kahi hoʻokolohua hoʻokolohua lapaʻau kahi noiʻi noiʻi i manaʻo ʻia e kōkua i ka hoʻomaikaʻi ʻana i nā mālama ʻana i kēia manawa a i ʻole loaʻa ka ʻike e pili ana i nā mālama hou no nā maʻi me ka maʻi ʻaʻai. Ke hōʻike nā hoʻokolohua hoʻokolohua ʻoi aku ka maikaʻi o kahi lapaʻau hou ma mua o ka maʻamau maʻamau, lilo paha ka lāʻau hou i ka lapaʻau maʻamau. Makemake paha nā mea maʻi e noʻonoʻo e pili ana i ka hoʻokolokolo ʻana. ʻO kekahi mau hoʻokolohua hoʻokolohua e hāmama wale i nā mea maʻi i hoʻomaka ʻole i ka lāʻau.
ʻO ka mālama ʻana no ka myelodysplastic syndrome e komo pū me ka mālama kōkua, ka lāʻau lapaʻau, a me ka transplantation cell stem.
ʻO nā mea maʻi me ka myelodysplastic maʻi i loaʻa nā ʻōuli i hoʻokumu ʻia e nā helu haʻahaʻa o ke koko e hāʻawi ʻia i ke kōkua kōkua e hōʻoluʻolu i nā hōʻailona a hoʻomaikaʻi i ka maikaʻi o ke ola. Hoʻohana ʻia ka lāʻau lapaʻau e hōʻohi i ka holomua o ka maʻi. Hiki ke hoʻōla ʻia kekahi mau mea maʻi me ka hana hoʻomāinoino me chemotherapy a ukali ʻia e ka transplant cell stem e hoʻohana ana i nā cell stem mai kahi mea hāʻawi.
Hoʻohana ʻia ʻekolu ʻano o ka mālama maʻamau.
Mālama kākoʻo
Hāʻawi ʻia ke kākoʻo kākoʻo e hōʻemi i nā pilikia i hoʻokumu ʻia e ka maʻi a i ʻole kāna mālama ʻana. Hoʻokomo ʻia ka mālama i kākoʻo i kēia mau mea:
- Hoʻoiho transfusion
ʻO ke Transfusion therapy (ke hoʻololi koko) kahi hana o ka hāʻawi ʻana i nā hunaola ʻulaʻula, nā ʻula koko keʻokeʻo, a i ʻole nā platelet e pani i nā hunaola koko i luku ʻia e ka maʻi a i ʻole ka lāʻau. Hāʻawi ʻia kahi transfusion o ke koko ʻulaʻula ke haʻahaʻa ka helu o ke koko ʻulaʻula a ʻike ʻia nā hōʻailona a i ʻole nā ʻōuli o ka anemia, e like me ka hanu ʻana a me ka luhi loa. Hāʻawi ʻia kahi transfusion platelet i ka wā e kahe ana ka mea maʻi, ke loaʻa nei kahi kaʻina hana e kumu ai ke kahe ʻana, a i ka wā e haʻahaʻa loa ai ka helu platelet.
ʻO nā mea maʻi i loaʻa i ka nui o nā transfusions o ke koko e loaʻa paha i ka ʻino a me nā ʻino o ke kino i hoʻokumu ʻia e ke kūkulu ʻia o ka hao nui. Hiki ke mālama ʻia kēia mau mea maʻi me ka lāʻau chelization iron e hoʻoneʻe ai i ka hao keu mai ke koko.
- Nā ʻākena hoʻonāukiuki ʻo Erythropoiesis
Hiki ke hāʻawi ʻia i nā ʻākena hoʻonāukiuki Erythropoiesis (ESAs) e hoʻonui i ka nui o nā hunaola ʻulaʻula makua i hana ʻia e ke kino a hoʻemi i nā hopena o anemia. I kekahi manawa hāʻawi ʻia ka granulositte colony-stimulate factor (G-CSF) me nā ESA e kōkua i ka hana ʻoi aku ka maikaʻi.
- Laʻau lāʻau Antibiotic
Hāʻawi ʻia nā antibiotic e hakakā i ka maʻi.
Laʻau lāʻau
- Lenalidomide
- ʻO nā mea maʻi me ka myelodysplastic syndrome e pili pū ana me kahi del (5q) chromosome abnormal abnormalities e pono ai ke mālama pinepine ʻia i ke koko ʻulaʻula e mālama ʻia me lenalidomide. Hoʻohana ʻia ʻo Lenalidomide e hoʻemi i ka pono no ka hoʻoliʻiliʻi o ke koko ʻulaʻula.
- Hoʻoikaika Immunosuppressive
- Hana ʻo Antithymocyte globulin (ATG) e kāohi a hoʻonāwaliwali paha i ka ʻōnaehana pale. Hoʻohana ʻia ia e hoʻoliʻiliʻi i ka pono no ka hoʻoliʻiliʻi o ke koko ʻulaʻula.
- ʻO Azacitidine a me decitabine
- Hoʻohana ʻia ʻo Azacitidine a me decitabine e mālama i nā syndrome myelodysplastic e ka luku ʻana i nā hunaola e māhele wikiwiki nei. Kōkua pū lākou i nā gen i pili i ka ulu ʻana o ka cell e hana e like me kā lākou e pono ai. ʻO ka mālama ʻana me azacitidine a me decitabine e hoʻolohi i ka holomua o ka myelodysplastic syndromes i ka leukemia myeloid koʻikoʻi.
- Hoʻohana ʻia ʻo Chemotherapy i ka leukemia myeloid koʻikoʻi (AML)
- ʻO nā mea maʻi me ka myelodysplastic syndrome a me ka nui o nā blasts i kā lākou iwi iwi ka nui o ka maʻi leukemia. Hiki ke mālama ʻia lākou me ka regima chemotherapy like i hoʻohana ʻia i nā mea maʻi me ka leukemia myeloid koʻikoʻi.
ʻO Chemotherapy me ka transplant cell stem
Hāʻawi ʻia ʻo Chemotherapy e pepehi i nā hunaola maʻi ʻaʻai. Hoʻopau pū ʻia nā hunaola olakino, e like me nā hunaola koko, e ka lāʻau maʻi ʻaʻai. ʻO ka transplant cell Stem kahi lapaʻau e pani i nā hunaola koko. Lawe ʻia nā hunaola ʻōpala (ʻaʻaʻa ʻole o ke koko) mai ke koko a i ʻole ka iwi o ka mea maʻi a i ʻole he mea hāʻawi a hoʻopaʻa ʻia a mālama ʻia. Ma hope o ka pau ʻana o ka chemotherapy i ka mea hoʻomanawanui, hoʻoheheʻe ʻia nā pūnaewele i mālama ʻia a hoʻihoʻi ʻia i ka mea maʻi ma o ka infusion. E ulu kēia mau hunaola i (a hoʻihoʻi) i nā huna koko o ke kino.
ʻAʻole hiki ke hana maikaʻi kēia lāʻau i nā mea maʻi i loaʻa i ka myelodysplastic syndrome e ka lāʻau i hala no ka maʻi ʻaʻai.
Ke hoʻāʻo ʻia nei nā ʻano lapaʻau hou i nā hoʻokolohua hoʻokolohua.
Loaʻa nā ʻike e pili ana i nā hoʻokolohua hoʻokolohua mai ka pūnaewele NCI.
ʻO ka mālama ʻana no ka myelodysplastic syndrome ke kumu i nā hopena ʻaoʻao.
No ka ʻike e pili ana i nā hopena i hopena ʻia e ka lapaʻau ʻana no ka maʻi ʻaʻai, e ʻike i kā mākou ʻaoʻao ʻaoʻao ʻaoʻao.
Makemake paha nā mea maʻi e noʻonoʻo e pili ana i ka hoʻokolokolo ʻana.
No kekahi mau mea maʻi, ke komo nei i ka hoʻokolohua hoʻokolohua ke koho lapaʻau maikaʻi loa paha. ʻO nā hoʻokolohua hoʻokolohua kahi ʻāpana o ka noiʻi ʻana o ka maʻi ʻaʻai. Hana ʻia nā hoʻokolohua hoʻokolohua e ʻike inā palekana a maikaʻi a maikaʻi paha nā hoʻomaʻamaʻa maʻi ʻaʻai ma mua o ka maʻamau maʻamau.
ʻO ka hapa nui o nā hana maʻamau no ka maʻi ʻaʻai i kau ʻia ma nā hoʻokolohua hoʻokolohua mua. ʻO nā mea maʻi i komo i ka hoʻokolokolo hoʻokolohua hiki ke loaʻa i ka lāʻau maʻamau a i ʻole i waena o nā mea mua i loaʻa kahi lāʻau hou.
ʻO nā mea maʻi i komo i nā hoʻokolohua hoʻokolohua kōkua pū kekahi i ka hoʻomaikaʻi ʻana i ke ʻano o ka mālama ʻana i ka maʻi ʻaʻai i ka wā e hiki mai ana. ʻOiai ʻaʻole nā alakaʻi hoʻokolohua e alakaʻi i nā hoʻoponopono hou maikaʻi, pane pinepine lākou i nā nīnau nui a kōkua i ka neʻe i mua o ka noiʻi.
Hiki i nā mea maʻi ke komo i nā hoʻokolohua hoʻokolohua ma mua, i ka wā, a ma hope paha o ka hoʻomaka ʻana i kā lākou lapaʻau.
Hoʻopili wale kekahi mau hoʻokolohua hoʻokolohua i nā mea maʻi i loaʻa ʻole ka lapaʻau. ʻO nā hoʻokolohua ʻē aʻe e hōʻoia i nā mālama ʻana no ka poʻe maʻi i loaʻa ʻole ka maikaʻi o ka maʻi ʻaʻai. Aia kekahi mau hoʻokolohua hoʻokolohua e hoʻāʻo i nā ala hou e hōʻoki i ka maʻi ʻaʻai mai ka hoʻi hou ʻana (hoʻi ʻana) a hōʻemi paha i nā hopena o ka mālama ʻana i ka maʻi ʻaʻai.
Ke mālama ʻia nei nā hoʻokolohua hoʻokolohua ma nā wahi he nui o ka ʻāina. Hiki ke ʻike ʻia ka ʻike e pili ana i nā hoʻokolohua hoʻokolohua e kākoʻo ʻia e NCI ma ka pūnaewele ʻimi noiʻi hoʻokolohua a NCI. Hiki ke loaʻa nā hoʻokolohua hoʻokolohua i kākoʻo ʻia e nā hui ʻē aʻe ma ka pūnaewele ClinicalTrials.gov.
Pono paha nā hoʻokolohua ukali.
ʻO kekahi o nā hoʻokolohua i hana ʻia e hōʻoia i ka maʻi ʻaʻai a i ʻole e ʻike i ke kahua o ka maʻi ʻaʻaʻa e hana hou ʻia paha. E hana hou ʻia kekahi mau hōʻike i mea e ʻike ai i ka maikaʻi o ka mālama ʻana. Hoʻoholo ʻia nā hoʻoholo e pili ana inā e hoʻomau, hoʻololi, a kū paha i ka lāʻau ʻana ma nā hopena o kēia mau hoʻāʻo.
E hoʻomau ʻia kekahi o nā hoʻokolohua mai kēlā me kēia manawa ma hope o ka pau ʻana o ka lāʻau. Hiki i nā hopena o kēia mau hoʻāʻo ke hōʻike inā ua loli kou ʻano a i ʻole inā ua hoʻi hou ke kanesa. Kapa ʻia kēia mau hoʻāʻo i kekahi manawa nā hoʻokolohua ukali a i ʻole nā loiloi.
Nā koho lapaʻau no Myelodysplastic Syndromes
No ka ʻike e pili ana i nā lāʻau i helu ʻia ma lalo, e ʻike i ka ʻaoʻao Overtion Option Overview.
Nā koho maʻamau maʻamau no Myelodysplastic Syndromes
ʻO nā koho maʻamau maʻamau no ka myelodysplastic syndromes e komo pū ana:
- Mālama kākoʻo me hoʻokahi a ʻoi paha o kēia mau mea:
- Hoʻoiho transfusion.
- Nā ʻākena hoʻonāukiuki ʻo Erythropoiesis.
- Laʻau lāʻau Antibiotic.
- Nā hana e lohi i ka holomua i ka myeloid leukemia (AML).
- Lenalidomide.
- Hoʻoikaika Immunosuppressive.
- ʻO Azacitidine a me decitabine.
- Hoʻohana ʻia ʻo Chemotherapy i ka leukemia myeloid koʻikoʻi.
- ʻO Chemotherapy me ka transplant cell stem.
Hoʻomaʻamaʻa i nā Therapy-pili Myeloid Neoplasms
ʻO nā mea maʻi i mālama ʻia i ka wā i hala me chemotherapy a i ʻole radiation therapy hiki ke hoʻomohala i nā neoplasms myeloid e pili ana i kēlā therapy. ʻO nā koho lapaʻau e like me nā syndrome myelodysplastic ʻē aʻe.
E hoʻohana i kā mākou ʻimi hoʻokolohua hoʻokolohua e ʻike i nā hoʻokolohua hoʻokolohua maʻi maʻi i kākoʻo ʻia e NCI e ʻae nei i nā mea maʻi. Hiki iā ʻoe ke ʻimi i nā hoʻāʻo e pili ana i ke ʻano o ka maʻi ʻaʻai, ka makahiki o ka mea hoʻomanawanui, a kahi e hana ʻia ai nā hoʻokolokolo. Loaʻa nā ʻike laulā e pili ana i nā hoʻokolohua hoʻokolohua.
Nā koho lapaʻau no ka hoʻi hou ʻana a i ʻole Refractory Myelodysplastic Syndromes
No ka ʻike e pili ana i nā lāʻau i helu ʻia ma lalo, e ʻike i ka ʻaoʻao Overtion Option Overview.
ʻAʻohe mālama maʻamau no nā syndrome myelodysplastic i hoʻi hou ʻia. ʻO nā mea maʻi i pane ʻole ka maʻi ʻaʻai i ka lāʻau lapaʻau a i hoʻi mai paha ma hope o ka mālama ʻana e makemake paha lākou e komo i kahi hoʻokolokolo.
E hoʻohana i kā mākou ʻimi hoʻokolohua hoʻokolohua e ʻike i nā hoʻokolohua hoʻokolohua maʻi maʻi i kākoʻo ʻia e NCI e ʻae nei i nā mea maʻi. Hiki iā ʻoe ke ʻimi i nā hoʻāʻo e pili ana i ke ʻano o ka maʻi ʻaʻai, ka makahiki o ka mea hoʻomanawanui, a kahi e hana ʻia ai nā hoʻokolokolo. Loaʻa nā ʻike laulā e pili ana i nā hoʻokolohua hoʻokolohua.
E aʻo hou e pili ana i ka Myelodysplastic Syndromes
No ka ʻike hou aku mai ka National Cancer Institute e pili ana i ka myelodysplastic syndromes, e ʻike i ka mea aʻe:
- ʻO nā Transplant Cell-Blood Stem
No ka ʻike ākea maʻi ʻaʻai a me nā kumuwaiwai ʻē aʻe mai ka National Cancer Institute, e ʻike i ka mea aʻe:
- E pili ana i ka maʻi ʻaʻai
- Ke hoʻokū nei
- ʻO Chemotherapy a ʻo ʻoe: Kākoʻo no ka poʻe me ka maʻi ʻaʻai
- Radiation Therapy a ʻo ʻoe: Kākoʻo no ka poʻe me ka maʻi ʻaʻai
- Ke kāohi nei i ka maʻi ʻaʻai
- Nā nīnau e nīnau ai i kāu kauka e pili ana i ka maʻi ʻaʻai
- No nā mea ola a me nā mea mālama
- E pili ana i kēia Hōʻuluʻulu Manaʻo
