Types/myeloproliferative/patient/mds-mpd-treatment-pdq

Myelodysplastic / Myeloproliferative Neoplasms iapaau ana (®) –Patient Version

ʻIkepili Nui e pili ana i Myelodysplastic / Myeloproliferative Neoplasms

NA MANA KUNI

• ʻO Myelodysplastic / myeloproliferative neoplasms kahi hui o nā maʻi kahi e nui ai nā iwi keʻokeʻo o ka iwi iwi keʻokeʻo.

• Loaʻa nā hiʻohiʻona o Myelodysplastic / myeloproliferative neoplasms o nā syndrome myelodysplastic a me nā neoplasms myeloproliferative.

• Aia kekahi mau ʻano neoplasms myelodysplastic / myeloproliferative.

• Hoʻohana ʻia nā hoʻāʻo e nānā i ke koko a me ka iwi o ka iwi e ʻike (loaʻa) a hōʻoia i nā neoplasms myelodysplastic / myeloproliferative.

ʻO Myelodysplastic / myeloproliferative neoplasms kahi hui o nā maʻi kahi e nui ai nā iwi keʻokeʻo o ka iwi iwi keʻokeʻo.

ʻO Myelodysplastic / myeloproliferative neoplasms nā maʻi o ke koko a me ka iwi iwi.

Anatomi o ka iwi. Hana ʻia ka iwi i ka iwi kuʻupuʻu, ka iwi iwi, a me ka iwi iwi. Hana ka iwi kuikahi i ka papa waho o ka iwi. ʻIke ʻia ka iwi Spongy ma ka wēlau o nā iwi a loaʻa ka ʻula ʻula. Loaʻa ka iwi iwi ma waenakonu o ka hapa nui o nā iwi a nui nā kīʻaha koko. ʻElua ʻano o ka iwi iwi: ʻulaʻula a melemele. Aia i loko o ka momona ʻulaʻula ke aʻa koko i hiki ke lilo i mau ʻulaʻula koko, nā hunaola keokeo, a i ʻole nā ​​platelet Hana ʻia ka momona o ka melemele ka momona.

ʻO ka maʻamau, hana ka iwi o ka iwi i nā huna koko (ʻaʻa ʻole) e lilo i mau puʻuwai koko makua ma mua o ka manawa. Hiki i ke kinipōpō kūpoko ke lilo i cell cell myeloid a i ʻole ka cell stem lymphoid. Lilo ke kinipōpō limapiʻi i keʻena keokeo. E lilo i kahi cell myeloid stem i hoʻokahi o ʻekolu mau ʻano o nā hunaola makua oʻo:

• ʻO nā hunaola ʻulaʻula e lawe i ka oxygen a me nā mea ʻē aʻe i nā kinona āpau o ke kino.

• ʻO nā hunaola keʻokeʻo e hakakā i ka maʻi a me ka maʻi.

• ʻO nā pāpale e hana ana i ke kahe o ke koko e hōʻoki i ke kahe ʻana o ke kahe.

Hoʻonui ulu kino. Hele ke aʻa koʻokoʻo koko i nā ʻanuʻu he nui e lilo i ʻulaʻula koko, platelet, a i ʻole ke koko keʻokeʻo.

Loaʻa nā hiʻohiʻona o Myelodysplastic / myeloproliferative neoplasms o nā syndrome myelodysplastic a me nā neoplasms myeloproliferative.

I nā maʻi myelodysplastic, ʻaʻole oʻo ke aʻa koko i nā koloko koko ʻulaʻula olakino, nā hunaola keʻokeʻo, a i ʻole nā ​​platelet. ʻO nā hunaola kō ʻole, i kapa ʻia he blasts, hana ʻole i ke ala e pono ai a make i ka iwi iwi a i ʻole ma hope koke iho o ko lākou komo ʻana i loko o ke koko. A ʻo ka hopena, he mea liʻiliʻi nā kaola koko ʻulaʻula olakino, nā hunaola keʻokeʻo, a me nā platelet.

I nā maʻi myeloproliferative, ʻoi aku ka nui ma mua o ka helu maʻamau o nā hunaola koko i lilo i hoʻokahi a ʻoi paha ʻano o nā hunaola koko a hoʻonui pinepine ka helu o nā hunaola koko.

ʻO kēia hōʻuluʻulu manaʻo e pili ana i nā neoplasms i loaʻa nā hiʻohiʻona o nā maʻi myelodysplastic a me myeloproliferative. E ʻike i nā hōʻuluʻulu aʻe no ka ʻike hou aku e pili ana i nā maʻi pili.

• Lapaʻau Myelodysplastic Syndromes

• Mālama Myeloproliferative Neoplasms iapaau ana

• Mālama Myelogenous Leukemia Hana

Aia kekahi mau ʻano neoplasms myelodysplastic / myeloproliferative.

ʻO nā ʻano nui ʻekolu o ka myelodysplastic / myeloproliferative neoplasms me kēia mau mea:

• ʻO ka leukemia myelomonosittic maʻi (CMML).

• ʻO ka leukemia myelomonosittic juvenile (JMML).

• ʻO ka leukemia myelogenous maʻi atypical (CML).

Ke kūlike ʻole kahi neoplasm myelodysplastic / myeloproliferative i kekahi o kēia ʻano, kapa ʻia ia ʻo myelodysplastic / myeloproliferative neoplasm, unclassifiable (MDS / MPN-UC).

Myelodysplastic / myeloproliferative neoplasms hiki ke holomua i ka leukemia koʻikoʻi.

Hoʻohana ʻia nā hoʻāʻo e nānā i ke koko a me ka iwi o ka iwi e ʻike (loaʻa) a hōʻoia i nā neoplasms myelodysplastic / myeloproliferative.

Hiki ke hoʻohana ʻia nā hoʻāʻo a me nā kaʻina hana aʻe:

• ʻO ka hoʻāʻo kino a me ka mōʻaukala: kahi hōʻike o ke kino e nānā i nā hōʻailona laulā o ke olakino, e like me ka nānā ʻana i nā hōʻailona o ka maʻi e like me ka spleen hoʻonui a me ke ake. E lawe ʻia kahi moʻolelo o nā ʻano olakino o ka mea maʻi a me nā maʻi i hala a me nā mālama ʻana.

• Helu piha ke koko (CBC) me ka ʻokoʻa: kahi kaʻina hana e huki ʻia ai kahi hāpana o ke koko a nānā ʻia no kēia mau mea:

• ʻO ka helu o nā hunaola ʻulaʻula a me nā platelet.

• ʻO ka helu a me ke ʻano o nā hunaola keokeo.

• ʻO ka nui o ka hemoglobin (ka protein i hāpai i ka oxygen) i loko o nā hunaola ʻulaʻula.

• ʻO ka ʻāpana o ka laʻana i hana ʻia i nā hunaola ʻulaʻula.

Helu piha ke koko (CBC). Hōʻiliʻili ʻia ke koko ma ka hoʻokomo ʻana i kahi nila i loko o kahi aa a ʻae i ke kahe o ke koko i loko o kahi paipu. Hoʻouna ʻia ka laʻana koko i ke keʻena hoʻokolohua a helu ʻia nā ʻulaʻula o ke koko, nā hunaola keokeo, a me nā platelet. Hoʻohana ʻia ka CBC e hoʻāʻo ai, e hōʻoia ai, a nānā i nā ʻano like ʻole.

• Hoʻopili ke koko peripheral: kahi hana e nānā ʻia ai kahi hāpana o ke koko no nā hunaola puhi, ka helu a me nā ʻano o nā hunaola keokeo, ka helu o nā platelet, a me nā hoʻololi i ke kinona o nā hunaola koko.

• Nā aʻo kemika koko: kahi hana e nānā ʻia ai kahi hāpana koko e ana i ka nui o kekahi mau mea i hoʻokuʻu ʻia i loko o ke koko e nā mea a me nā mea i loko o ke kino. ʻO kahi mea maʻamau (ʻoi aʻe a i ʻole haʻahaʻa ma mua o ka maʻamau) o kahi mea hiki ke lilo i hōʻailona o ka maʻi.

• ʻO ka ʻiʻo o ka iwi iwi a me ka biopsy: Ka lawe ʻana i kahi ʻāpana o ka iwi a me ka iwi iwi ma ka hoʻokomo ʻana i kahi nila i loko o ka hipbone a i ʻole ka umauma. ʻIke kahi pathologist i nā laʻana o ka iwi a me ka iwi iwi ma lalo o kahi microscope e nānā no nā hunaola ʻokoʻa.

ʻIʻini iwi a me ka biopsy. Ma hope o ka helu ʻia ʻana o kahi ʻili o ka ʻili, hoʻokomo ʻia kahi nila o ka iwi iwi i ka iwi ʻūhā o ka mea maʻi. Lawe ʻia nā laʻana o ke koko, ka iwi, a me ka iwi o ka iwi no ka ninaninau ʻana ma lalo o kahi microscope.

E hana ʻia paha nā hoʻokolohua aʻe ma ka laʻana o nā kiko i lawe ʻia.

• Nānā Cytogenetic: kahi hoʻokolohua hoʻokolohua kahi e helu ai nā chromosome o nā hunaola i kahi hāpana o ka iwi iwi a i ʻole ke koko no nā loli, e like me ka haki, nalowale, hoʻoponopono hou ʻia, a i ʻole nā ​​chromosome keu. ʻO nā loli i kekahi mau chromosome he hōʻailona ia o ka maʻi ʻaʻai. Hoʻohana ʻia ka hoʻoponopono Cytogenetic e kōkua i ke kuhi ʻana i ka maʻi ʻaʻai, e hoʻolālā i ka lāʻau ʻana, a i ʻole e ʻike i ke ʻano o ka maikaʻi o ka mālama ʻana. ʻAʻohe i loko o nā hunaola maʻi ʻaʻai i loko o ka myelodysplastic / myeloproliferative neoplasms ka chromosome Philadelphia i loaʻa i ka leukemia myelogenous mau.

• Immunocytochemistry: kahi hoʻokolohua hoʻokolohua e hoʻohana ai i nā anti -antibodies e nānā ai no kekahi antigens (markers) i kahi laʻana o ka iwi iwi o ka mea maʻi. Hoʻopili pinepine ʻia nā mea ʻino i kekahi enzyme a i ʻole ka waihoʻoluʻu fluorescent. Ma hope o ka hoʻopili ʻana o nā mea ʻume i ka antigen i ka laʻana o ka iwi iwi o ka mea hoʻomanawanui, e hoʻoulu ʻia ka ʻimene a me ka kala, a laila ʻike ʻia ka antigen ma lalo o kahi microscope. Hoʻohana ʻia kēia ʻano hoʻokolohua e kōkua i ke kuhi ʻana i ka maʻi ʻaʻai a me ka haʻi ʻana i ka ʻokoʻa ma waena o myopodysplastic / myeloproliferative neoplasms, leukemia, a me nā kūlana ʻē aʻe.

ʻO Leukemia Myelomonocytic mau loa

NA MANA KUNI

• ʻO ka leukemia myelomonosittic maʻi mau kahi maʻi kahi i hana ʻia ai nā myelosit a me nā monositita (nā keʻokeʻo o ke koko keʻokeʻo ʻole) i ka momona o ka iwi.

• ʻO ka ʻelemakule makahiki a me ke kāne e hoʻonui i ka makaʻu o ka leukemia myelomonosittic mau.

• ʻO nā hōʻailona a me nā ʻōuli o ka leukemia myelomonocytic mau loa e pili ana i ke kuni, ka pohō kaumaha, a me ka luhi loa.

• Kū kekahi mau kumu i ka wānana (kahi o ke ola ʻana) a me nā koho lapaʻau.

ʻO ka leukemia myelomonosittic maʻi mau kahi maʻi kahi i hana ʻia ai nā myelosit a me nā monositita (nā keʻokeʻo o ke koko keʻokeʻo ʻole) i ka momona o ka iwi.

I ka leukemia myelomonosittic mau loa (CMML), haʻi ke kino i ka nui o nā hunaola koko e lilo i ʻelua mau ʻano kikoʻī keokeo i kapa ʻia he myelocytes a me nā monocytes. ʻAʻole lilo kekahi o kēia mau koʻokoʻo koko i oʻo i nā hunaola keokeo makua. Kapa ʻia kēia mau hunaola keʻokeʻo oʻo ʻole I ka hala ʻana o ka manawa, nā myelosit, monositita, a me nā pahū e hoʻopuka i nā hunaola ʻulaʻula a me nā pā i loko o ka iwi iwi. Ke hiki mai kēia, maʻi, anemia, a i ʻole ke kahe maʻalahi.

ʻO ka ʻelemakule makahiki a me ke kāne e hoʻonui i ka makaʻu o ka leukemia myelomonosittic mau.

ʻO nā mea āpau e hoʻonui i kou manawa e loaʻa ai kahi maʻi i kapa ʻia he kumu weliweli. ʻO nā kumuhana kūpono no ka CMML me kēia mau mea:

• Makahiki.
• Ke kāne.
• Ke hōʻike ʻia nei i kekahi mau mea i ka hana a i ʻole ke kaiapuni.
• Ke hōʻike ʻia nei i ka radiation.
• Ka hana i hala me kekahi mau lāʻau anticancer.

ʻO nā hōʻailona a me nā ʻōuli o ka leukemia myelomonocytic mau loa e pili ana i ke kuni, ka pohō kaumaha, a me ka luhi loa.

ʻO CMML a i ʻole nā ​​ʻano ʻē aʻe nā kumu ʻē aʻe a me nā ʻōuli ʻē aʻe. E hōʻoia me kāu kauka inā loaʻa iā ʻoe kekahi o kēia mau mea:

• Fiva no ke kumu ʻole i ʻike ʻia.
• Maʻi kīnā.
• Luhi nui loa.
• ʻO ka hōʻemi kaumaha no ke kumu ʻole.
• Pākuʻi maʻalahi a hoʻokahe paha.
• ʻO ka ʻeha a i ʻole ka manaʻo o ka piha ma lalo o nā iwi ʻaoʻao.

Kū kekahi mau kumu i ka wānana (kahi o ke ola ʻana) a me nā koho lapaʻau.

ʻO ka wānana (loaʻa o ke ola) a me nā koho lapaʻau no CMML kaukaʻi ʻia i ka mea aʻe:

• ʻO ka helu o nā hunaola keʻokeʻo a i ʻole nā ​​platelet i ke koko a i ʻole ka iwi iwi.

• Inā he maʻi anemia ka mea maʻi.

• Ka nui o nā pahū i ke koko a i ʻole ka iwi iwi.

• Ka nui o ka hemoglobin i nā hunaola ʻulaʻula.

• Inā loaʻa kekahi mau hoʻololi i nā chromosome.

ʻO Juvenile Myelomonosittic Leukemia

NA MANA KUNI

• ʻO ka leukemia myelomonosittic ʻo Juvenile kahi maʻi maʻi ʻōpio kahi i nui ai nā myelosit a me nā monositita (nā keʻokeʻo o ke koko keʻokeʻo ʻole) i hana ʻia i ka iwi o ka iwi.

• ʻO nā ʻōuli a me nā ʻōuli o ka leelemia myelomonosittic ʻōpio me ka fiva, ka pohō o ke kaumaha, a me ka luhi loa.

• Kū kekahi mau kumu i ka wānana (kahi o ke ola ʻana) a me nā koho lapaʻau.

ʻO ka leukemia myelomonosittic ʻo Juvenile kahi maʻi maʻi ʻōpio kahi i nui ai nā myelosit a me nā monositita (nā keʻokeʻo o ke koko keʻokeʻo ʻole) i hana ʻia i ka iwi o ka iwi.

ʻO ka leukemia myelomonosittic juvenile (JMML) kahi maʻi ʻaʻa kamaliʻi liʻiliʻi i ʻike pinepine ʻia i nā keiki ma mua o 2 mau makahiki. ʻO nā keiki i loaʻa i ka neurofibromatosis type 1 a me nā kāne he nui ka nui o ka leukemia myelomonosittic juvenile.

I ka JMML, haʻi ke kino i ka nui o nā hunaola koko e lilo i ʻelua ʻano keokeo keokeo i kapa ʻia ʻo myelocytes a me nā monocytes. ʻAʻole lilo kekahi o kēia mau koʻokoʻo koko i oʻo i nā hunaola keokeo makua. Kapa ʻia kēia mau hunaola keʻokeʻo oʻo ʻole I ka hala ʻana o ka manawa, nā myelosit, monositita, a me nā pahū e hoʻopuka i nā hunaola ʻulaʻula a me nā pā i loko o ka iwi iwi. Ke hiki mai kēia, maʻi, anemia, a i ʻole ke kahe maʻalahi.

ʻO nā ʻōuli a me nā ʻōuli o ka leelemia myelomonosittic ʻōpio me ka fiva, ka pohō o ke kaumaha, a me ka luhi loa.

ʻO JMML a i ʻole nā ​​kumu ʻē aʻe e pili ana i kēia mau hōʻailona a me nā ʻōuli ʻē aʻe. E hōʻoia me kāu kauka inā loaʻa iā ʻoe kekahi o kēia mau mea:

• Fiva no ke kumu ʻole i ʻike ʻia.

• Loaʻa nā maʻi, e like me ka bronchitis a i ʻole ka tonsillitis.

• Luhi nui loa.

• Pākuʻi maʻalahi a hoʻokahe paha.

• ʻ Skinhū ʻili.

• ʻO ka pehu ʻole o nā lymph node i ka ʻāʻī, underarm, ʻōpū, a me nā ʻūhū.

• ʻO ka ʻeha a i ʻole ka manaʻo o ka piha ma lalo o nā iwi ʻaoʻao.

Kū kekahi mau kumu i ka wānana (kahi o ke ola ʻana) a me nā koho lapaʻau.

ʻO ka wānana (loaʻa o ke ola) a me nā koho lapaʻau no JMML kaukaʻi ʻia i ka mea aʻe:

• ʻO ka makahiki o ke keiki i ka hōʻoia ʻana.

• ʻO ka helu o nā platelet i ke koko.

• Ka nui o kekahi ʻano hemoglobin i nā hunaola ʻulaʻula.

Atypical Chronic Myelogenous Leukemia

NA MANA KUNI

• ʻO ka leukemia myelogenous maʻi atypical mau loa kahi maʻi kahi i hana ʻia ai nā granulocytes he nui loa (nā keʻokeʻo o ke koko keʻokeʻo ʻole) i ka momona o ka iwi.

• ʻO nā hōʻailona a me nā ʻōuli o ka leukemia myelogenous maʻi atypical e pili ana i ka palu maʻalahi a i ke kahe ʻana a me ka luhi a nāwaliwali hoʻi.

• Kū kekahi mau kumu i ka wānana (kahi o ke ola ʻana).

ʻO ka leukemia myelogenous maʻi atypical mau loa kahi maʻi kahi i hana ʻia ai nā granulocytes he nui loa (nā keʻokeʻo o ke koko keʻokeʻo ʻole) i ka momona o ka iwi.

I ka leypemia myelogenous mau maʻi atypical (CML), haʻi ke kino i ka nui o nā hunaola koko e lilo i ʻano keokeo keokeo i kapa ʻia he granulocytes. ʻAʻole lilo kekahi o kēia mau koʻokoʻo koko i oʻo i nā hunaola keokeo makua. Kapa ʻia kēia mau hunaola keʻokeʻo oʻo ʻole I ka hala ʻana o ka manawa, hoʻolaha nā granulocytes a me nā pupuhi i nā hunaola ʻulaʻula a me nā platelet i ka iwi iwi.

ʻO nā leukemia i loko o CM atypical a CML ke ʻano like ma lalo o kahi microscope. Eia nō naʻe, i ka CML hui ʻino ʻole, hoʻololi ʻia kekahi chromosome, i kapa ʻia ʻo "Philadelphia chromosome" ʻaʻole ma laila.

ʻO nā hōʻailona a me nā ʻōuli o ka leukemia myelogenous maʻi atypical e pili ana i ka palu maʻalahi a i ke kahe ʻana a me ka luhi a nāwaliwali hoʻi.

ʻO kēia a me nā ʻōuli a me nā ʻōuli ʻē aʻe i kumu ʻia e ka atypical CML a i ʻole nā ​​kūlana ʻē aʻe. E hōʻoia me kāu kauka inā loaʻa iā ʻoe kekahi o kēia mau mea:

• Pokole o ka hanu.

• ʻIli pale.

• Luhi loa a nawaliwali hoʻi.

• Pākuʻi maʻalahi a hoʻokahe paha.

• Petechiae (pālahalaha, kiko kiko ma lalo o ka ʻili i hoʻokumu ʻia e ke kahe ʻana o ke kahe).

• ʻO ka ʻeha a i ʻole ke ʻano o ka piha ma lalo o nā iwi ʻaoʻao ma ka ʻaoʻao hema.

Kū kekahi mau kumu i ka wānana (kahi o ke ola ʻana).

ʻO ka wānana (loaʻa o ke ola) no CML atypical kaukaʻi ʻia i ka nui o nā hunaola ʻulaʻula a me nā platelet i loko o ke koko.

Myelodysplastic / Myeloproliferative Neoplasm, Unclassifiable

NA MANA KUNI

• ʻO Myelodysplastic / myeloproliferative neoplasm, unclassifiable, kahi maʻi i loaʻa nā hiʻohiʻona o nā maʻi myelodysplastic a me myeloproliferative akā ʻaʻole ia he leukemia myelomonosittic mau, leukemia myelomonosittic ʻōpio, a me leukemia myelogenous mau.

• Nā ʻōuli a me nā ʻōuli o ka myelodysplastic / myeloproliferative neoplasm, unclassifiable, me ka fiva, ke kaupaona, a me ka luhi loa.

ʻO Myelodysplastic / myeloproliferative neoplasm, unclassifiable, kahi maʻi i loaʻa nā hiʻohiʻona o nā maʻi myelodysplastic a me myeloproliferative akā ʻaʻole ia he leukemia myelomonosittic mau, leukemia myelomonosittic ʻōpio, a me leukemia myelogenous mau.

I ka myelodysplastic / myeloproliferative neoplasm, unclassifiable (MDS / MPD-UC), haʻi ke kino i nā hunaola koko he nui e lilo i mau ʻula koko ʻulaʻula, nā hunaola keʻokeʻo, a i ʻole nā ​​platelet. ʻAʻole lilo kekahi o kēia mau puʻupuʻu koko i mau hunaola makua. Kapa ʻia kēia mau hunaola koko makua ʻole he blasts. I ka hala ʻana o ka manawa, hoʻolauna nā huna koko ʻokoʻa a poha i ka iwi o ka iwi i nā hunaola ʻulaʻula olakino, nā hunaola keʻokeʻo, a me nā platelet.

He maʻi maʻi laha ʻole ʻo MDS / MPN-UC. Ma muli o ka mea liʻiliʻi loa, ʻike ʻole ʻia nā kumu e hoʻopili i ka makaʻu a me ka wānana.

Nā ʻōuli a me nā ʻōuli o ka myelodysplastic / myeloproliferative neoplasm, unclassifiable, me ka fiva, ke kaupaona, a me ka luhi loa.

Nā MDS / MPN-UC a i ʻole nā ​​kūlana ʻē aʻe i hoʻokumu ʻia ai kēia mau hōʻailona a me nā ʻōuli ʻē aʻe. E hōʻoia me kāu kauka inā loaʻa iā ʻoe kekahi o kēia mau mea:

• ʻO ka maʻi fiva a i ʻole pinepine paha.

• Pokole o ka hanu.

• Luhi loa a nawaliwali hoʻi.

• ʻIli pale.

• Pākuʻi maʻalahi a hoʻokahe paha.

• Petechiae (pālahalaha, kiko kiko ma lalo o ka ʻili i hoʻokumu ʻia e ke kahe ʻana o ke kahe).

• ʻO ka ʻeha a i ʻole ka manaʻo o ka piha ma lalo o nā iwi ʻaoʻao.

Nā pae o Myelodysplastic / Myeloproliferative Neoplasms

NA MANA KUNI

• ʻAʻohe ʻōnaehana hoʻonohonoho maʻamau no nā neoplasms myelodysplastic / myeloproliferative.

ʻAʻohe ʻōnaehana hoʻonohonoho maʻamau no nā neoplasms myelodysplastic / myeloproliferative.

ʻO ke kau ʻana ke hana e ʻike ai i ka lōʻihi o ka laha ʻana o ka maʻi ʻaʻai. ʻAʻohe ʻōnaehana hoʻonohonoho maʻamau no nā neoplasms myelodysplastic / myeloproliferative. Hoʻokumu ʻia ka lapaʻau ʻana ma ke ʻano o ka myelodysplastic / myeloproliferative neoplasm a ka mea maʻi. He mea nui e ʻike i ke ʻano i mea e hoʻolālā ai i ka lāʻau.

Laulā Manaʻo Option Oponopono

NA MANA KUNI

• Aia nā ʻano lapaʻau like ʻole no nā mea maʻi me nā neoplasma myelodysplastic / myeloproliferative.

• Hoʻohana ʻia nā ʻano ʻelima o ka mālama maʻamau.

• ʻO Chemotherapy

• Laau lāʻau ʻē aʻe

• Ke kuʻi ʻōnaʻi ʻōnaeho

• Mālama kākoʻo

• Pahuhopu kau ʻia

• Ke hoʻāʻo ʻia nei nā ʻano lapaʻau hou i nā hoʻokolohua hoʻokolohua.

• ʻO ka mālama ʻana no ka myelodysplastic / myeloproliferative neoplasms ke kumu o ka hopena.

• Makemake paha nā mea maʻi e noʻonoʻo e pili ana i ka hoʻokolokolo ʻana.

• Hiki i nā mea maʻi ke komo i nā hoʻokolohua hoʻokolohua ma mua, i ka wā, a ma hope paha o ka hoʻomaka ʻana i kā lākou mālama maʻi ʻaʻai.

• Pono paha nā hoʻokolohua ukali.

Aia nā ʻano lapaʻau like ʻole no nā mea maʻi me nā neoplasma myelodysplastic / myeloproliferative.

Loaʻa nā ʻano lapaʻau like ʻole no nā mea maʻi me nā neoplasma myelodysplastic / myeloproliferative. Kūlana maʻamau kekahi mau hōʻailona (ʻo ka lāʻau i hoʻohana ʻia i kēia manawa), a ʻo kekahi e hoʻāʻo ʻia nei i nā hoʻokolohua hoʻokolohua. ʻO kahi hoʻokolohua hoʻokolohua lapaʻau kahi noiʻi noiʻi i manaʻo ʻia e kōkua i ka hoʻomaikaʻi ʻana i nā mālama ʻana i kēia manawa a i ʻole loaʻa ka ʻike e pili ana i nā mālama hou no nā maʻi me ka maʻi ʻaʻai. Ke hōʻike nā hoʻokolohua hoʻokolohua ʻoi aku ka maikaʻi o kahi lapaʻau hou ma mua o ka maʻamau maʻamau, lilo paha ka lāʻau hou i ka lapaʻau maʻamau. Makemake paha nā mea maʻi e noʻonoʻo e pili ana i ka hoʻokolokolo ʻana. ʻO kekahi mau hoʻokolohua hoʻokolohua e hāmama wale i nā mea maʻi i hoʻomaka ʻole i ka lāʻau.

Hoʻohana ʻia nā ʻano ʻelima o ka mālama maʻamau.

ʻO Chemotherapy

ʻO Chemotherapy kahi lāʻau lapaʻau maʻi maʻi e hoʻohana i nā lāʻau e hōʻoki i ka ulu ʻana o nā hunaola maʻi ʻaʻai, ma ka luku ʻana i nā hunaola a i ʻole ke kāpae ʻana iā lākou mai ka hoʻokaʻawale. Ke lawe ʻia ka chemotherapy e ka waha a i ʻole injected i loko o kahi aa koko a i ʻole nā ​​mākala, komo nā lāʻau i ke kahe o ke koko a hiki ke kiʻi i nā hunaola maʻi ʻōpio i loko o ke kino (chemotherapy ʻōnaehana). Ke waiho pololei ʻia ka chemotherapy i loko o ka wai cerebrospinal, kahi hui, a i ʻole ke kino o ke kino e like me ka ʻōpū, ʻo nā lāʻau lapaʻau ka mea nui e hoʻopili i nā hunaola maʻi ʻaʻai i kēlā mau wahi (chemotherapy āpau). Hāʻawi ʻia ke ala o ka chemotherapy i ka ʻano a me ke kahua o ka maʻi ʻaʻai e mālama ʻia. Hoʻohui ka chemotherapy hui me ka hoʻohana ʻana ma mua o hoʻokahi lāʻau anticancer.

E ʻike i nā lāʻau i ʻae ʻia no Myeloproliferative Neoplasms no ka ʻike hou aku.

Laau lāʻau ʻē aʻe

ʻO ka 13-cis retinoic acid kahi lāʻau like me ka wikamina e lohi ai i ka hiki ʻana o ka maʻi ʻaʻai e hana i nā hunaola maʻi ʻē aʻe a hoʻololi i ke ʻano a me ka hana a kēia mau hunaola.

Ke kuʻi ʻōnaʻi ʻōnaeho

Hāʻawi ʻia ʻo Chemotherapy e pepehi i nā hunaola ʻino a i ʻole nā ​​pūnaʻi maʻi ʻaʻai. Hoʻopau pū ʻia nā hunaola olakino, e like me nā hunaola koko, e ka lāʻau maʻi ʻaʻai. ʻO ka transplant cell Stem kahi lapaʻau e pani i nā hunaola koko. Lawe ʻia nā hunaola ʻōpala (ʻaʻaʻa ʻole o ke koko) mai ke koko a i ʻole ka iwi o ka mea maʻi a i ʻole he mea hāʻawi a hoʻopaʻa ʻia a mālama ʻia. Ma hope o ka pau ʻana o ka chemotherapy i ka mea hoʻomanawanui, hoʻoheheʻe ʻia nā pūnaewele i mālama ʻia a hoʻihoʻi ʻia i ka mea maʻi ma o ka infusion. E ulu kēia mau hunaola i (a hoʻihoʻi) i nā huna koko o ke kino.

Ke kuʻi ʻōnaʻi ʻōnaeho. (ʻAnuʻu 1): Lawe ʻia ke koko mai kahi aa i ka lima o ka mea hāʻawi. ʻO ka mea hoʻomanawanui a kanaka ʻē aʻe paha ka mea hāʻawi. Kahe ke koko i loko o kahi mīkini e hemo i nā hunaola kūmole. A laila hoʻihoʻi ʻia ke koko i ka mea hāʻawi ma o kahi aa i loko o ka lima ʻē aʻe. (ʻAnuʻu 2): Loaʻa i ka mea maʻi ka chemotherapy e pepehi i nā hunaola koko. Loaʻa i ka mea maʻi ka radiation radiation (ʻaʻole i hōʻike ʻia). (ʻAnuʻu 3): Loaʻa i ka mea maʻi ka maʻi ma o ka catheter i hoʻokomo ʻia i loko o kahi kīʻaha koko i ka umauma.

Mālama kākoʻo

Hāʻawi ʻia ke kākoʻo kākoʻo e hōʻemi i nā pilikia i hoʻokumu ʻia e ka maʻi a i ʻole kāna mālama ʻana. Hiki i ke kōkua kākoʻo ke hoʻopili i ka transfusion therapy a i ʻole ka lāʻau hoʻomohala lāʻau, e like me nā antibiotic e hakakā i ka maʻi.

Pahuhopu kau ʻia

ʻO ka hoʻomālama ʻia kahi lāʻau lapaʻau e hoʻohana i nā lāʻau a i ʻole nā ​​mea ʻē aʻe e hoʻouka aku i nā hunaola maʻi ʻaʻai me ka ʻole e hōʻeha i nā hunaola maʻamau. Hoʻohana ʻia nā lāʻau lapaʻau i māka ʻia i kapa ʻia ʻo nā tyrosine kinase inhibitors (TKI) e mālama i ka neoplasm myelodysplastic / myeloproliferative, unclassifiable. Pākuʻu ʻo TKI i ka enzyme, tyrosine kinase, i kumu e lilo nā hunaola i nā hunaʻi koko (blasts) ma mua o ke kino e pono ai. ʻO Imatinib mesylate (Gleevec) kahi TKI hiki ke hoʻohana ʻia. Ke aʻo ʻia nei nā lāʻau lapaʻau hoʻomōhala ʻē aʻe i ka mālama ʻia ʻana o JMML.

E ʻike i nā lāʻau i ʻae ʻia no Myeloproliferative Neoplasms no ka ʻike hou aku.

Ke hoʻāʻo ʻia nei nā ʻano lapaʻau hou i nā hoʻokolohua hoʻokolohua.

Loaʻa nā ʻike e pili ana i nā hoʻokolohua hoʻokolohua mai ka pūnaewele NCI.

ʻO ka mālama ʻana no ka myelodysplastic / myeloproliferative neoplasms ke kumu o ka hopena.

No ka ʻike e pili ana i nā hopena i hopena ʻia e ka lapaʻau ʻana no ka maʻi ʻaʻai, e ʻike i kā mākou ʻaoʻao ʻaoʻao ʻaoʻao.

Makemake paha nā mea maʻi e noʻonoʻo e pili ana i ka hoʻokolokolo ʻana.

No kekahi mau mea maʻi, ke komo nei i ka hoʻokolohua hoʻokolohua ke koho lapaʻau maikaʻi loa paha. ʻO nā hoʻokolohua hoʻokolohua kahi ʻāpana o ka noiʻi ʻana o ka maʻi ʻaʻai. Hana ʻia nā hoʻokolohua hoʻokolohua e ʻike inā palekana a maikaʻi a maikaʻi paha nā hoʻomaʻamaʻa maʻi ʻaʻai ma mua o ka maʻamau maʻamau.

ʻO ka hapa nui o nā hana maʻamau no ka maʻi ʻaʻai i kau ʻia ma nā hoʻokolohua hoʻokolohua mua. ʻO nā mea maʻi i komo i ka hoʻokolokolo hoʻokolohua hiki ke loaʻa i ka lāʻau maʻamau a i ʻole i waena o nā mea mua i loaʻa kahi lāʻau hou.

ʻO nā mea maʻi i komo i nā hoʻokolohua hoʻokolohua kōkua pū kekahi i ka hoʻomaikaʻi ʻana i ke ʻano o ka mālama ʻana i ka maʻi ʻaʻai i ka wā e hiki mai ana. ʻOiai ʻaʻole nā ​​alakaʻi hoʻokolohua e alakaʻi i nā hoʻoponopono hou maikaʻi, pane pinepine lākou i nā nīnau nui a kōkua i ka neʻe i mua o ka noiʻi.

Hiki i nā mea maʻi ke komo i nā hoʻokolohua hoʻokolohua ma mua, i ka wā, a ma hope paha o ka hoʻomaka ʻana i kā lākou mālama maʻi ʻaʻai.

Hoʻopili wale kekahi mau hoʻokolohua hoʻokolohua i nā mea maʻi i loaʻa ʻole ka lapaʻau. ʻO nā hoʻokolohua ʻē aʻe e hōʻoia i nā mālama ʻana no ka poʻe maʻi i loaʻa ʻole ka maikaʻi o ka maʻi ʻaʻai. Aia kekahi mau hoʻokolohua hoʻokolohua e hoʻāʻo i nā ala hou e hōʻoki i ka maʻi ʻaʻai mai ka hoʻi hou ʻana (hoʻi ʻana) a hōʻemi paha i nā hopena o ka mālama ʻana i ka maʻi ʻaʻai.

Ke mālama ʻia nei nā hoʻokolohua hoʻokolohua ma nā wahi he nui o ka ʻāina. Hiki ke ʻike ʻia ka ʻike e pili ana i nā hoʻokolohua hoʻokolohua e kākoʻo ʻia e NCI ma ka pūnaewele ʻimi noiʻi hoʻokolohua a NCI. Hiki ke loaʻa nā hoʻokolohua hoʻokolohua i kākoʻo ʻia e nā hui ʻē aʻe ma ka pūnaewele ClinicalTrials.gov.

Pono paha nā hoʻokolohua ukali.

ʻO kekahi o nā hoʻokolohua i hana ʻia e hōʻoia i ka maʻi ʻaʻai a i ʻole e ʻike i ke kahua o ka maʻi ʻaʻaʻa e hana hou ʻia paha. E hana hou ʻia kekahi mau hōʻike i mea e ʻike ai i ka maikaʻi o ka mālama ʻana. Hoʻoholo ʻia nā hoʻoholo e pili ana inā e hoʻomau, hoʻololi, a kū paha i ka lāʻau ʻana ma nā hopena o kēia mau hoʻāʻo.

E hoʻomau ʻia kekahi o nā hoʻokolohua mai kēlā me kēia manawa ma hope o ka pau ʻana o ka lāʻau. Hiki i nā hopena o kēia mau hoʻāʻo ke hōʻike inā ua loli kou ʻano a i ʻole inā ua hoʻi hou ke kanesa. Kapa ʻia kēia mau hoʻāʻo i kekahi manawa nā hoʻokolohua ukali a i ʻole nā ​​loiloi.

Nā koho lapaʻau no Myelodysplastic / Myeloproliferative Neoplasms

Ma keia Pauku

• ʻO Leukemia Myelomonocytic mau loa

• ʻO Juvenile Myelomonosittic Leukemia

• Atypical Chronic Myelogenous Leukemia

• Myelodysplastic / Myeloproliferative Neoplasm, Unclassifiable

No ka ʻike e pili ana i nā lāʻau i helu ʻia ma lalo, e ʻike i ka ʻaoʻao Overtion Option Overview.

ʻO Leukemia Myelomonocytic mau loa

ʻO ka mālama ʻana i ka leukemia myelomonosittic mau (CMML) hiki ke hoʻopili ʻia i kēia mau mea:

• Chemotherapy me hoʻokahi a ʻoi paha nā ʻākena.

• Ke kuʻi ʻōnaʻi ʻōnaeho.

• ʻO kahi hoʻokolohua hoʻokolohua o kahi lapaʻau hou.

E hoʻohana i kā mākou ʻimi hoʻokolohua hoʻokolohua e ʻike i nā hoʻokolohua hoʻokolohua maʻi maʻi i kākoʻo ʻia e NCI e ʻae nei i nā mea maʻi. Hiki iā ʻoe ke ʻimi i nā hoʻāʻo e pili ana i ke ʻano o ka maʻi ʻaʻai, ka makahiki o ka mea hoʻomanawanui, a kahi e hana ʻia ai nā hoʻokolokolo. Loaʻa nā ʻike laulā e pili ana i nā hoʻokolohua hoʻokolohua.

ʻO Juvenile Myelomonosittic Leukemia

ʻO ka mālama ʻana i ka leukemia myelomonosittic ʻōpio (JMML) hiki ke hoʻopili ʻia i kēia mau mea:

• Hoʻohui chemotherapy.

• Ke kuʻi ʻōnaʻi ʻōnaeho.

• 13-cis-retinoic acid kūkaʻi.

• ʻO kahi hoʻokolohua hoʻokolohua o kahi lapaʻau hou, e like me ka therapist target.

E hoʻohana i kā mākou ʻimi hoʻokolohua hoʻokolohua e ʻike i nā hoʻokolohua hoʻokolohua maʻi maʻi i kākoʻo ʻia e NCI e ʻae nei i nā mea maʻi. Hiki iā ʻoe ke ʻimi i nā hoʻāʻo e pili ana i ke ʻano o ka maʻi ʻaʻai, ka makahiki o ka mea hoʻomanawanui, a kahi e hana ʻia ai nā hoʻokolokolo. Loaʻa nā ʻike laulā e pili ana i nā hoʻokolohua hoʻokolohua.

Atypical Chronic Myelogenous Leukemia

ʻO ka mālama ʻana i ka leukemia myelogenous maʻi atypical (CML) hiki ke hoʻopili ʻia me chemotherapy.

E hoʻohana i kā mākou ʻimi hoʻokolohua hoʻokolohua e ʻike i nā hoʻokolohua hoʻokolohua maʻi maʻi i kākoʻo ʻia e NCI e ʻae nei i nā mea maʻi. Hiki iā ʻoe ke ʻimi i nā hoʻāʻo e pili ana i ke ʻano o ka maʻi ʻaʻai, ka makahiki o ka mea hoʻomanawanui, a kahi e hana ʻia ai nā hoʻokolokolo. Loaʻa nā ʻike laulā e pili ana i nā hoʻokolohua hoʻokolohua.

Myelodysplastic / Myeloproliferative Neoplasm, Unclassifiable

Ma muli o ka neoplasm myelodysplastic / myeloproliferative, unclassifiable (MDS / MPN-UC) kahi maʻi laha ʻole, ʻike iki ʻia e pili ana i kāna mālama ʻana. Hoʻomaopopo ʻia ka hana penei:

• Nā mālama mālama mālama e mālama i nā pilikia i hoʻokumu ʻia e ka maʻi e like me ka maʻi, ke kahe ʻana o ke koko, a me ka anemia.

• Hoʻolālā pahuhopu (imatinib mesylate).

E hoʻohana i kā mākou ʻimi hoʻokolohua hoʻokolohua e ʻike i nā hoʻokolohua hoʻokolohua maʻi maʻi i kākoʻo ʻia e NCI e ʻae nei i nā mea maʻi. Hiki iā ʻoe ke ʻimi i nā hoʻāʻo e pili ana i ke ʻano o ka maʻi ʻaʻai, ka makahiki o ka mea hoʻomanawanui, a kahi e hana ʻia ai nā hoʻokolokolo. Loaʻa nā ʻike laulā e pili ana i nā hoʻokolohua hoʻokolohua.

E aʻo hou e pili ana i nā Myelodysplastic / Myeloproliferative Neoplasms

No ka ʻike hou aku mai ka National Cancer Institute e pili ana i ka myelodysplastic / myeloproliferative neoplasms, e nānā i kēia:

• ʻAoʻao Myopoproliferative Neoplasms

• ʻO nā Transplant Cell-Blood Stem

• Ua ʻae ʻia nā lāʻau no Myeloproliferative Neoplasms

• ʻO nā Therapy Cancer i kau ʻia

No ka ʻike ākea maʻi ʻaʻai a me nā kumuwaiwai ʻē aʻe mai ka National Cancer Institute, e ʻike i ka mea aʻe:

• E pili ana i ka maʻi ʻaʻai

• Ke hoʻokū nei

• ʻO Chemotherapy a ʻo ʻoe: Kākoʻo no ka poʻe me ka maʻi ʻaʻai

• Radiation Therapy a ʻo ʻoe: Kākoʻo no ka poʻe me ka maʻi ʻaʻai

• Ke kāohi nei i ka maʻi ʻaʻai

• Nā nīnau e nīnau ai i kāu kauka e pili ana i ka maʻi ʻaʻai

• No nā mea ola a me nā mea mālama