Nā ʻano / myeloma / hoʻomanawanui / myeloma-lapaʻau-pdq
Nā ʻikepili i loko
- 1 ʻO nā Neoplasms Pūnaewele Plasma (Me My Multoma Multiple) Hoʻomaʻamaʻa (®) - Mana Mana Manaʻo
- 1.1 ʻO ka ʻike ākea e pili ana i nā Neoplasms Plasma Cell
- 1.2 Nā kahua o ka Plasma Cell Neoplasms
- 1.3 Laulā Manaʻo Option Oponopono
- 1.4 Hoʻomaʻamaʻa i ka Monoclonal Gammopathy o ka Undetermined Significance
- 1.5 Iapaau ana o kaʻawale Plasmacytoma o ka iwi
- 1.6 Ka mālama ʻana iā Extramedullary Plasmacytoma
- 1.7 Lapaʻau o Multiple Myeloma
- 1.8 Hoʻomaʻamaʻa i ka Releled or Refractory Multiple Myeloma
- 1.9 E aʻo hou aʻe e pili ana i nā Neoplasms Plasma Cell
ʻO nā Neoplasms Pūnaewele Plasma (Me My Multoma Multiple) Hoʻomaʻamaʻa (®) - Mana Mana Manaʻo
ʻO ka ʻike ākea e pili ana i nā Neoplasms Plasma Cell
NA MANA KUNI
- ʻO nā neoplasms Plasma cell he mau maʻi ia e hana ai ke kino i nā keena plasma he nui loa.
- Hiki ke lilo nā neoplasms Plasma cell i mea maikaʻi (ʻaʻole ka maʻi ʻaʻai) a i ʻole malignant (kanesa).
- Nui a hewahewa nā ʻano neoplasms o ka cell plasma.
- ʻO ka gammopathy Monoclonal o ke koʻikoʻi undetermined (MGUS)
- Plasmacytoma
- Myeloma lehulehu
- Hiki i ka myeloma maha a me nā neoplasms pūnaewele plasma ke kumu i kahi ʻano i kapa ʻia ʻo amyloidosis.
- Hiki i ka makahiki ke hoʻopili i ka makaʻu o ka neoplasms cell plasma.
- Hoʻohana ʻia nā hoʻokolohua e nānā i ke koko, ka iwi iwi, a me ka mimi e ʻike pono i nā myeloma he nui a me nā neoplasms pūnaewele plasma ʻē aʻe.
- Kū kekahi mau kumu i ka wānana (kahi o ke ola ʻana) a me nā koho lapaʻau.
ʻO nā neoplasms Plasma cell he mau maʻi ia e hana ai ke kino i nā keena plasma he nui loa.
Hoʻolālā nā hunaola Plasma mai nā lymphocytes B (B cells), kahi ʻano o ke keʻokeʻo keʻokeʻo e hana ʻia i ka iwi iwi. ʻO ka maʻamau, ke komo ka bacteria a me nā mea ʻino i loko o ke kino, e loli kekahi o nā hunaola B i mau hunaola plasma. Hana nā hunaola plasma i nā mea pale e hakakā i nā koʻohune a me nā mea hoʻomaʻi, e hoʻōki i ka maʻi a me nā maʻi.
ʻO nā neoplasms Plasma cell he maʻi ia e hana ai nā hunaola plasma ʻino a i ʻole nā hunaola myeloma i nā iwi i loko o nā iwi a i ʻole nā palupalu o ke kino. Hana pū nā hunaola plasma i kahi protein palahalaha, i kapa ʻia ʻo ka protein M, ʻaʻole pono ia e ke kino a ʻaʻole kōkua i ka hakakā ʻana i ka maʻi. Kūkulu kēia mau proteine antibody i loko o ka iwi iwi a hiki ke hoʻopulu i ke koko a i ʻole hiki ke hōʻino i nā puʻupaʻa.
Hiki ke lilo nā neoplasms Plasma cell i mea maikaʻi (ʻaʻole ka maʻi ʻaʻai) a i ʻole malignant (kanesa).
ʻO Monoclonal gammopathy o ke koʻikoʻi undetermined (MGUS) ʻaʻole ka maʻi ʻaʻai akā hiki ke lilo i maʻi ʻaʻai. ʻO nā ʻano like ʻole o neoplasms cell plasma he maʻi ʻaʻai.
- Lymphoplasmacytic lymphoma. (E ʻike i ka hoʻomaʻamaʻa Lymphoma makua non-Hodgkin no ka ʻike hou aku.)
- Plasmacytoma.
- Myeloma lehulehu.
Nui a hewahewa nā ʻano neoplasms o ka cell plasma.
Hoʻopili nā neoplasms cell plasma i kēia:
ʻO ka gammopathy Monoclonal o ke koʻikoʻi undetermined (MGUS)
I kēia ʻano neoplasm cell cell, ma lalo o 10% o ka momona o ka iwi i hana ʻia i nā hunaola plasma maʻamau a ʻaʻohe maʻi ʻaʻai. Hana nā hunaola plasma ʻokoʻa i ka protein M, kahi i loaʻa i kekahi manawa i ke kahe maʻamau a i ʻole ka mimi. I ka hapa nui o nā mea maʻi, noho like ka nui o ka protein M a ʻaʻohe hōʻailona, hōʻailona, a me nā pilikia olakino.
I kekahi mau mea maʻi, hiki i ka MGUS ke lilo i kūlana ʻoi aku ke koʻikoʻi, e like me ka amyloidosis, a i ʻole ke kumu o nā pilikia me nā puʻupaʻa, ka puʻuwai, a me nā aʻa. Hiki i ka MGUS ke lilo i maʻi ʻaʻai, e like me myeloma maha, lymphoplasmacytic lymphoma, a i ʻole leukemia lymphocytic mau.
Plasmacytoma
I kēia ʻano neoplasm cell cell plasma, aia nā hunaola plasma maʻamau (myeloma cells) ma kahi hoʻokahi a hana i hoʻokahi tumo, i kapa ʻia he plasmacytoma. I kekahi manawa hiki ke hoʻōla ʻia ka plasmacytoma. ʻElua ʻano plasmacytoma.
- I ka plasmacytoma kaʻawale o ka iwi, loaʻa kahi tumo hunaola plasma i ka iwi, ma lalo o 10% o ka iwi iwi i hana ʻia me nā hunaola plasma, a ʻaʻohe hōʻailona ʻē aʻe o ke kanesa. Lilo pinepine ka Plasmacytoma o ka iwi i mau myeloma.
- I ka plasmacytoma extramedullary, loaʻa kahi tumo hunaola plasma i loko o nā mea palupalu akā ʻaʻole ma ka iwi a me ka iwi o ka iwi. Hoʻokumu pinepine ʻia nā plasmacytomas extramedullary i nāʻaʻa o ka ʻāʻī, tonsil, a me nā sinus paranasal.
Pili nā hōʻailona a me nā ʻōuli i kahi o ka tumo.
- I ka iwi, hiki i ka plasmacytoma ke hana i ka ʻeha a i ʻole nā iwi haʻihaʻi.
- I nā mea palupalu, hiki i ka tumo ke kaomi ma nā wahi kokoke a hōʻeha i ka ʻeha a i ʻole nā pilikia ʻē aʻe. ʻO kahi laʻana, hiki i kahi plasmacytoma i ka puʻu ke paʻakikī e ale.
Myeloma lehulehu
I nā myeloma he nui, kūkulu ʻia nā hunaola plasma ʻino (myeloma cells) i loko o ka iwi iwi a hana i nā tumors i nā iwi he nui o ke kino. Mālama paha kēia mau tumors i ka momona o ka iwi mai ka hana ʻana i nā hunaola keu olakino maikaʻi. ʻO ka maʻamau, hana ka iwi iwi i nā hunaola (ʻole o nā hunaola) i lilo i ʻekolu ʻano o nā hunaola makua oʻo:
- ʻO nā hunaola ʻulaʻula e lawe i ka oxygen a me nā mea ʻē aʻe i nā kinona āpau o ke kino.
- ʻO nā hunaola keʻokeʻo e hakakā i ka maʻi a me ka maʻi.
- ʻO nā pāpale e hana ana i nā kīʻaha koko e kōkua i ka pale ʻana i ke kahe ʻana.
Ke piʻi nei ka nui o nā hunaola myeloma, ʻoi aku ka liʻiliʻi o nā hunaola ʻulaʻula, nā ʻula koko keʻokeʻo, a me nā platelet i hana ʻia. Hoʻopilikia a hoʻonāwaliwali hoʻi nā iwi myeloma i ka iwi.
I kekahi manawa ʻaʻole kumu myeloma maha i nā hōʻailona a i ʻole nā ʻōuli. Kapa ʻia kēia e puhi ana i nā myeloma he nui. ʻIke ʻia paha ke hana ʻia kahi hōʻoia koko a mimi paha no kekahi ʻano ʻē aʻe. Hoʻokumu ʻia nā hōʻailona a me nā ʻōuli e ka myeloma he nui a i ʻole nā kūlana ʻē aʻe. E hōʻoia me kāu kauka inā loaʻa iā ʻoe kekahi o kēia mau mea:
- ʻEha iwi, ʻo ka hoʻi ma ka hope a i ʻole nā iwi ʻaoʻao.
- Iwi nahae wale.
- ʻO ke kuni no ke kumu a me nā maʻi pinepine ʻole.
- Pākuʻi maʻalahi a hoʻokahe paha.
- Hī pilikia.
- Nāwaliwali o nā lima a me nā wāwae.
- Luhi nui loa.
Hiki i kahi tumo ke hoʻopōʻino i ka iwi a hana i ka hypercalcemia (ʻo ka nui o ka puna i loko o ke koko). Hiki i kēia ke hoʻololi i nā ʻōpū he nui i ke kino, e like me nā puʻupaʻa, nā ʻalolo, ka puʻuwai, nā mākala, a me nā wahi digestive, a hana i nā pilikia olakino koʻikoʻi.
Hiki i ka Hypercalcemia ke hana i kēia mau hōʻailona a me nā hōʻailona:
- Loaʻa ka ʻai ʻole.
- Nausea a i ʻole ka luaʻi.
- Manaʻo make wai.
- Urination pinepine.
- Konipōpō.
- Luhi nui loa.
- Nāwaliwali ka ʻiʻo.
- Hoʻomaha ʻole.
- Huikau a pilikia manaʻo paha.
Hiki i ka myeloma maha a me nā neoplasms pūnaewele plasma ke kumu i kahi ʻano i kapa ʻia ʻo amyloidosis.
I nā hihia maʻamau, hiki i ka myeloma maha ke kumu i nā ʻalolo ākea (nā ʻalolo ʻaʻole i ka lolo a i ʻole nā iwi kuamoo) a hāʻule nā lālā. Hiki ke kumu ʻia kēia e kahi ʻano i kapa ʻia ʻo amyloidosis. Kūkulu a hoʻopaʻa pū nā protein Antibody i nā aʻalolo ākea a me nā meaola, e like me ka puʻupaʻa a me ka puʻuwai. Hiki i kēia ke hana i nā aʻalolo a me nā mea ʻoʻoleʻa e paʻakikī a hiki ʻole ke hana i ke ala e pono ai.
Hoʻokumu paha ʻo Amyloidosis i nā ʻōuli a me nā hōʻailona penei:
- Luhi nui loa.
- Nā kiko poni ma ka ʻili.
- Alelo hoʻonui ʻia.
- Pohā.
- ʻO ka pehu ʻana ma muli o ka wai i nāʻaʻaʻa o kou kino.
- ʻO ke kani a i ʻole ka helu ʻana i kou mau wāwae a me kou mau wāwae.
Hiki i ka makahiki ke hoʻopili i ka makaʻu o ka neoplasms cell plasma.
ʻO nā mea āpau e hoʻonui i kou makaʻu i ka loaʻa ʻana i kahi maʻi i kapa ʻia he kumu weliweli. ʻO ka loaʻa ʻana o kahi mea pilikia ʻaʻole ia he kumu e loaʻa ʻoe i ka maʻi ʻaʻai. ʻaʻohe o nā kumu pilikia ʻaʻole ia he kumu ʻaʻole ʻoe e loaʻa i ka maʻi ʻaʻai. E kamaʻilio me kāu kauka inā manaʻo ʻoe ua makaʻu paha ʻoe.
ʻO nā neoplasma Plasma cell he maʻa mau i ka poʻe i waena a ʻelemakule paha. No ka myeloma maha a me ka plasmacytoma, ʻo nā kumu pilikia ʻē aʻe e pili pū me kēia:
- ʻEleʻele.
- Ke kāne.
- Loaʻa i kahi moʻolelo pilikino o MGUS a i ʻole plasmacytoma.
- Ke hōʻike ʻia nei i ka radiation a i ʻole kekahi mau kemika.
Hoʻohana ʻia nā hoʻokolohua e nānā i ke koko, ka iwi iwi, a me ka mimi e ʻike pono i nā myeloma he nui a me nā neoplasms pūnaewele plasma ʻē aʻe.
Hiki ke hoʻohana ʻia nā hoʻāʻo a me nā kaʻina hana aʻe:
- ʻO ka hoʻāʻo kino a me ka mōʻaukala olakino: kahi hōʻike o ke kino e nānā i nā hōʻailona laulā o ke olakino, e like me ka nānā ʻana i nā hōʻailona o ka maʻi, e like me nā puʻupuʻu a i ʻole nā mea ʻē aʻe e ʻano ʻē. E lawe ʻia kahi moʻolelo o nā ʻano olakino o ka mea maʻi a me nā maʻi i hala a me nā mālama ʻana.
- Ke koko a me ka mimi immunoglobulin haʻawina: A ina hana i loko i ke koko a me ka mimi hāpana, kulana kupono e ana i na dala o kekahi nā mea'aʻaʻa (immunoglobulins). No nā myeloma he nui, beta-2-microglobulin, protein M, nā kaulahao kukui manuahi, a me nā protein ʻē aʻe i hana ʻia e nā hunaʻi myeloma. ʻO kahi kiʻekiʻe ma mua o ka maʻamau o kēia mau mea i hiki ke lilo i hōʻailona o ka maʻi.
- ʻO ka ʻiʻo o ka iwi iwi a me ka biopsy: Ka hemo ʻana o ka iwi iwi, ke koko, a me kahi ʻāpana o ka iwi ma ka hoʻokomo ʻana i kahi kui kolo i loko o ka hipbone a i ʻole ka umauma. ʻIke kahi pathologist i ka momona o ka iwi, ke koko, a me ka iwi ma lalo o kahi microscope e nānā no nā hunaola ʻokoʻa.
E hana ʻia paha kēia mau hoʻāʻo e pili ana i ka hāpana o nā mea i lawe ʻia i ka wā o ka ʻiʻini o ka iwi iwi a me ka biopsy.
- Nānā Cytogenetic: kahi hoʻokolohua hoʻokolohua kahi e helu ai nā chromosome o nā hunaola i kahi hāpana o ka iwi iwi a nānā ʻia no nā loli, e like me ka haki, nalowale, hoʻoponopono hou ʻia, a i ʻole nā chromosome keu. ʻO nā loli i kekahi mau chromosome he hōʻailona ia o ka maʻi ʻaʻai. Hoʻohana ʻia ka hoʻoponopono Cytogenetic e kōkua i ke kuhi ʻana i ka maʻi ʻaʻai, e hoʻolālā i ka lāʻau ʻana, a i ʻole e ʻike i ke ʻano o ka maikaʻi o ka mālama ʻana.
- FISH (fluorescence in situ hybridization): kahi hoʻokolohua hoʻokolohua i hoʻohana ʻia e nānā a helu i nā gen a i ʻole nā chromosome i nā pūnaewele a me nā aʻa. Hana ʻia nā ʻāpana o ka DNA i loaʻa nā waihoʻoluʻu fluorescent i loko o ke keʻena hoʻokolohua a hoʻohui ʻia i kahi laʻana o nā hunaola a me nā aʻa o ka mea maʻi. Ke hoʻopili aku kēia mau ʻāpana DNA i kala ʻia i kekahi mau ʻāpana a i ʻole nā wahi o chromosome i loko o ka hāpana, hoʻomālamalama lākou ke nānā ʻia ma lalo o kahi microscope fluorescent. Hoʻohana ʻia ka hōʻike FISH e kōkua i ke kuhi ʻana i ka maʻi ʻaʻai a kōkua i ka hoʻolālā ʻana i ka lāʻau.
- Kahe uila ʻili pūnaewele. Hoʻopili ʻia nā hunaola mai kahi hāpana o ka iwi iwi o ka mea maʻi me ka pena wai fluorescent, waiho ʻia i loko o kahi wai, a laila hele kekahi i kēlā me kēia manawa ma ke kaola o ke kukui. Hoʻokumu ʻia nā hopena o ka hoʻāʻo e pili ana i ka hopena o nā hunaola i hoʻohuehue ʻia me ka pena fluorescent i ke kaola o ke kukui. Hoʻohana ʻia kēia hoʻokolohua e kōkua i ke kuhi a mālama ʻana i kekahi ʻano o nā maʻi ʻaʻai, e like me leukemia a me lymphoma.
- Nūhou iwi iwi: i ka ana iwi iwi iwi, lawe ʻia nā kukuna x o nā iwi āpau i ke kino. Hoʻohana ʻia nā kukuna x e ʻimi i nā wahi kahi i hōʻino ʻia ka iwi. ʻO ka x-ray kahi ʻano kukuna ikehu e hiki ke hele ma waena o ke kino a ma ke kiʻi ʻoniʻoni, e hana ana i kiʻi o nā wahi i loko o ke kino.
- Helu piha ke koko (CBC) me ka ʻokoʻa: kahi kaʻina hana e huki ʻia ai kahi hāpana o ke koko a nānā ʻia no kēia mau mea:
- ʻO ka helu o nā hunaola ʻulaʻula a me nā platelet.
- ʻO ka helu a me ke ʻano o nā hunaola keokeo.
- ʻO ka nui o ka hemoglobin (ka protein i hāpai i ka oxygen) i loko o nā hunaola ʻulaʻula.
- ʻO ka ʻāpana o ka hāpana koko i hana ʻia i nā hunaola ʻulaʻula.
- Nā aʻo kemika koko: kahi hana e nānā ʻia ai kahi laʻana koko e ana i ka nui o kekahi mau mea, e like me ka calcium a albumin paha, i hoʻokuʻu ʻia i loko o ke koko e nā mea a me nā mea i loko o ke kino. ʻO kahi mea maʻamau (ʻoi aʻe a i ʻole haʻahaʻa ma mua o ka maʻamau) o kahi mea hiki ke lilo i hōʻailona o ka maʻi.
- Iwakāluakūmāhā hola ho'āʻo: He hoʻāʻo kahi e ʻohiʻohi ʻia ai ka mimi no 24 mau hola e ana i ka nui o kekahi mau mea. ʻO kahi mea maʻamau (ʻoi aku a i ʻole haʻahaʻa ma mua o ka maʻamau) o kahi mea i hiki ke lilo i hōʻailona o ka maʻi i loko o ka meaola a i ʻole ke ʻano. ʻO kahi kiʻekiʻe ma mua o ka nui o nā protein hiki i kahi hōʻailona o ka myeloma maha.
- MRI (kiʻi resonance ʻume mākenēki): kahi hana e hoʻohana ai i ka magnet, nā nalu lekiō, a me kahi kamepiula e hana i kahi moʻo o nā kiʻi kikoʻī o nā wahi i loko o ke kino. Kāhea ʻia kēia kaʻina hana he kiʻi nukelea kiʻi resonance (NMRI). Hiki ke hoʻohana ʻia kahi MRI o ka ʻāʻī a me ke pelvis e ʻimi i nā wahi kahi i hōʻino ʻia ka iwi.
- PET scan (positron emission tomography scan): kahi hana e loaʻa ai nā puʻupuʻu tumo malignant i loko o ke kino. Hoʻokomo ʻia kahi liʻiliʻi o ka glucose radioactive (kō) i loko o kahi aa koko. Hoʻopili ka scanner PET a puni ke kino a hana i kahi kiʻi o kahi e hoʻohana ʻia ai ka glucose i ke kino. ʻOi aku ka mālamalama o nā hunaola tumo ma ke kiʻi no ka mea ʻoi aku ka hana a lawe i ka glucose ma mua o ka hana ʻana o nā hunaola maʻamau.
- CT scan (CAT scan): Kahi hana e hana ai i ka moʻo o nā kiʻi kikoʻī o nā wahi i loko o ke kino, e like me ka iwi kuamoʻo, i lawe ʻia mai nā ʻaoʻao ʻokoʻa. Hana ʻia nā kiʻi e kahi kamepiula i hoʻopili ʻia i kahi mīkini x-ray. Hoʻokomo ʻia paha ke kala i loko o ke aa a i ʻole ale ʻia e kōkua i nā ʻōpū a i ʻole nā kino i hōʻike hou aku me ka maopopo. Kāhea ʻia kēia kaʻina hana he tomography i helu ʻia, kamepiula tomography, a i ʻole he tomography axial computerized.
- Nānā PET-CT: kahi hana e hoʻohui i nā kiʻi mai kahi scan tomography emission positron (PET) a me kahi scan tomography i helu ʻia (CT). Hana ʻia nā paʻi PET a me CT ma ka manawa like me ka mīkini like. Hāʻawi nā scans i hoʻohui ʻia i nā kiʻi kikoʻī o nā wahi i loko o ke kino, e like me ke kuamoʻo, ma mua o ka scan e hāʻawi ai iā ia iho.
Kū kekahi mau kumu i ka wānana (kahi o ke ola ʻana) a me nā koho lapaʻau.
Aia ka wānana i kēia mau mea:
- Ke ʻano o ka neoplasm pūnaewele cell.
- ʻO ke kahua o ka maʻi.
- Inā loaʻa kekahi immunoglobulin (antibody).
- Inā paha aia kekahi mau loli.
- Inā paha ua hōʻino ʻia ka hakuʻala.
- Inā pane ka maʻi ʻaʻai i ka lapaʻau mua a i ʻole recurs (hoʻi hou).
Pili nā koho lapaʻau i kēia:
- Ke ʻano o ka neoplasm pūnaewele cell.
- ʻO ka makahiki a me ke olakino olakino o ka mea maʻi.
- Inā paha he hōʻailona, hōʻailona, a me nā pilikia olakino, e like me ka hōʻino ʻana o ka puʻupaʻa a i ʻole ka maʻi, e pili ana i ka maʻi.
- Inā pane ka maʻi ʻaʻai i ka lapaʻau mua a i ʻole recurs (hoʻi hou).
Nā kahua o ka Plasma Cell Neoplasms
NA MANA KUNI
- ʻAʻohe ʻōnaehana hoʻonohonoho maʻamau no ka monoclonal gammopathy o ka nui i hoʻoholo ʻole ʻia (MGUS) a me ka plasmacytoma.
- Ma hope o ka loaʻa ʻana o kahi myeloma he nui, hana ʻia nā hoʻokolohua e ʻike i ka nui o ka maʻi ʻaʻai i loko o ke kino.
- Hoʻokumu ʻia ke kahua o ka myeloma maha ma luna o nā pae beta-2-microglobulin a me albumin i loko o ke koko.
- Hoʻohana ʻia nā pae aʻe no ka myeloma maha:
- ʻOihana I myeloma maha
- ʻOihana II mau myeloma
- ʻOihana III mau myeloma
- ʻAʻole hiki i nā neoplasms Plasma ke pane i ka lāʻau a hoʻi mai paha ma hope o ka lāʻau.
ʻAʻohe ʻōnaehana hoʻonohonoho maʻamau no ka monoclonal gammopathy o ka nui i hoʻoholo ʻole ʻia (MGUS) a me ka plasmacytoma.
Ma hope o ka loaʻa ʻana o kahi myeloma he nui, hana ʻia nā hoʻokolohua e ʻike i ka nui o ka maʻi ʻaʻai i loko o ke kino.
ʻO ke kaʻina hana e ʻike ai i ka nui o nā maʻi ʻaʻai i loko o ke kino i kapa ʻia he staging. He mea nui ia e ʻike i ke kahua i mea e hoʻolālā ai i ka lāʻau.
Hiki ke hoʻohana i nā hoʻokolohua a me nā kaʻina hana e ʻike ai i ka nui o ka maʻi ʻaʻai i loko o ke kino.
- Nūhou iwi iwi: i ka ana iwi iwi iwi, lawe ʻia nā kukuna x o nā iwi āpau i ke kino. Hoʻohana ʻia nā kukuna x e ʻimi i nā wahi kahi i hōʻino ʻia ka iwi. ʻO ka x-ray kahi ʻano kukuna ikehu e hiki ke hele ma waena o ke kino a ma ke kiʻi ʻoniʻoni, e hana ana i kiʻi o nā wahi i loko o ke kino.
- MRI (magnetic resonance imaging): Kahi hana e hoʻohana ai i ka magnet, nā nalu lekiō, a me kahi kamepiula e hana i nā kiʻi kikoʻī o nā wahi i loko o ke kino, e like me ka iwi o ka iwi. Kāhea ʻia kēia kaʻina hana he kiʻi nukelea kiʻi resonance (NMRI).
- Densitometry iwi: kahi hana e hoʻohana ai i kahi ʻano x-ray kūikawā e ana i ka nui o ka iwi.
Hoʻokumu ʻia ke kahua o ka myeloma maha ma luna o nā pae beta-2-microglobulin a me albumin i loko o ke koko.
Loaʻa ka beta-2-microglobulin a me albumin i ke koko. ʻO Beta-2-microglobulin kahi protein i loaʻa i nā hunaola plasma. ʻO Albumin ka hapa nui o ka plasma toto. Mālama ia i ka wai mai ke kahe ʻana o nā kīʻaha koko. Lawe pū ia i nā meaola i nā pūnaewele, a lawe i nā hormoni, nā wikamina, nā lāʻau, a me nā mea ʻē aʻe, e like me ka calcium, ma o ke kino. I ke koko o nā mea maʻi me ka myeloma he nui, hoʻonui ʻia ka nui o beta-2-microglobulin a hoʻemi ʻia ka nui o ka albumin.
Hoʻohana ʻia nā pae aʻe no ka myeloma maha:
ʻOihana I myeloma maha
I ka pae I myeloma maha, eia nā pae koko:
- ʻO ka pae beta-2-microglobulin ma lalo o 3.5 mg / L; a
- ʻO ka pae albumin he 3.5 g / dL a ʻoi paha.
ʻOihana II mau myeloma
I ka pae II mau myeloma, aia nā pae koko ma waena o nā pae no ka pae I a me ka pae III.
ʻOihana III mau myeloma
I ke kahua III nui myeloma, ʻo ke kiʻekiʻe o ke koko o beta-2-microglobulin ʻo 5.5 mg / L a ʻoi aku a ʻo ka mea hoʻomanawanui kekahi o kēia mau mea:
- nā pae kiʻekiʻe o ka lactate dehydrogenase (LDH); a i ʻole
- kekahi mau hoʻololi i nā chromosome.
ʻAʻole hiki i nā neoplasms Plasma ke pane i ka lāʻau a hoʻi mai paha ma hope o ka lāʻau.
Kāhea ʻia nā neoplasms o ka Plasma repractory ke piʻi mau nei ka nui o nā hunaola plasma ʻoiai hāʻawi ʻia ka lāʻau. Kāhea ʻia nā neoplasms o ka Plasma relapsed ke hoʻi mai lākou ma hope o ka lapaʻau ʻana.
Laulā Manaʻo Option Oponopono
NA MANA KUNI
- Aia nā ʻano lapaʻau like ʻole no nā mea maʻi me nā neoplasma pūnaewele plasma.
- Hoʻohana ʻia ʻewalu mau ʻano o ka mālama ʻana.
- ʻO Chemotherapy
- Laau lāʻau ʻē aʻe
- Pahuhopu kau ʻia
- ʻO ka chemotherapy kiʻekiʻe me ka transplant cell stem
- Immunotherapy
- Lapaʻau hoʻomākala
- ʻOki kino
- Ke kali kiaʻi nei
- Ke hoʻāʻo ʻia nei nā ʻano lapaʻau hou i nā hoʻokolohua hoʻokolohua.
- Hoʻohui hou o nā therapies
- Hoʻomaʻamaʻa no nā neoplasms pūnaewele plasma i nā hopena ʻaoʻao.
- Hāʻawi ʻia ke kākoʻo kākoʻo e hōʻemi i nā pilikia i hoʻokumu ʻia e ka maʻi a i ʻole kāna mālama ʻana.
- Makemake paha nā mea maʻi e noʻonoʻo e pili ana i ka hoʻokolokolo ʻana.
- Hiki i nā mea maʻi ke komo i nā hoʻokolohua hoʻokolohua ma mua, i ka wā, a ma hope paha o ka hoʻomaka ʻana i kā lākou mālama maʻi ʻaʻai.
- Pono paha nā hoʻokolohua ukali.
Aia nā ʻano lapaʻau like ʻole no nā mea maʻi me nā neoplasma pūnaewele plasma.
Loaʻa nā ʻano lapaʻau like ʻole no nā mea maʻi me nā neoplasms cell plasma. Kūlana maʻamau kekahi mau hōʻailona (ʻo ka lāʻau i hoʻohana ʻia i kēia manawa), a ʻo kekahi e hoʻāʻo ʻia nei i nā hoʻokolohua hoʻokolohua. ʻO kahi hoʻokolohua hoʻokolohua lapaʻau kahi noiʻi noiʻi i manaʻo ʻia e kōkua i ka hoʻomaikaʻi ʻana i nā mālama ʻana i kēia manawa a i ʻole loaʻa ka ʻike e pili ana i nā mālama hou no nā maʻi me ka maʻi ʻaʻai. Ke hōʻike nā hoʻokolohua hoʻokolohua ʻoi aku ka maikaʻi o kahi lapaʻau hou ma mua o ka maʻamau maʻamau, lilo paha ka lāʻau hou i ka lapaʻau maʻamau. Makemake paha nā mea maʻi e noʻonoʻo e pili ana i ka hoʻokolokolo ʻana. ʻO kekahi mau hoʻokolohua hoʻokolohua e hāmama wale i nā mea maʻi i hoʻomaka ʻole i ka lāʻau.
Hoʻohana ʻia ʻewalu mau ʻano o ka mālama ʻana.
ʻO Chemotherapy
ʻO Chemotherapy kahi lāʻau lapaʻau maʻi maʻi e hoʻohana i nā lāʻau e hōʻoki i ka ulu ʻana o nā hunaola maʻi ʻaʻai, ma ka luku ʻana i nā hunaola a i ʻole ke kāpae ʻana iā lākou mai ka hoʻokaʻawale. Ke lawe ʻia ka chemotherapy e ka waha a i ʻole injected i loko o kahi aa koko a i ʻole nā mākala, komo nā lāʻau i ke kahe o ke koko a hiki ke kiʻi i nā hunaola maʻi ʻōpio i loko o ke kino (chemotherapy ʻōnaehana).
E ʻike i nā lāʻau i ʻae ʻia no Myeloma maha a me nā Neoplasms Plasma Cell ʻē aʻe no ka ʻike hou aku.
Laau lāʻau ʻē aʻe
ʻO Corticosteroids nā steroid i loaʻa nā hopena antitumor i nā myeloma he nui.
Pahuhopu kau ʻia
He lāʻau lapaʻau i hoʻomākaukau ʻia e hoʻohana i nā lāʻau a i ʻole nā mea ʻē aʻe e ʻike a hoʻouka aku i nā hunaola maʻi ʻaʻai. Hiki i ka hoʻōla pahuhopu ke hōʻemi i ka hōʻeha i nā hunaola maʻamau ma mua o ka chemotherapy a i ʻole radiation radiation. Hiki ke hoʻohana ʻia i kekahi mau ʻano o ka hoʻomōhala hoʻomōhala e mālama ai i nā myeloma he nui a me nā neoplasms cell plasma. Aia kekahi mau ʻano o ka hoʻomōhala hoʻomāka ʻia.
- Hoʻomaʻamaʻa Proteasome mea hōʻoki: Kāki kēia hana i ka hana o nā proteasome i nā pūnaʻi maʻi maʻi ʻO ka proteasome kahi protein e lawe i nā protein ʻē aʻe ʻaʻole pono hou ʻia e ka cell. Ke hoʻoneʻe ʻole ʻia nā protein mai ke kolamu, kūkulu lākou i luna a make paha i ka make maʻi ʻaʻai. ʻO Bortezomib, carfilzomib, a me ixazomib nā mea kūpale proteasome i hoʻohana ʻia i ka mālama ʻana i nā myeloma he nui a me nā neoplasms cell plasma ʻē aʻe.
- Monoclonal antibody therapy: hoʻohana kēia hana i nā mea pale i hana ʻia i loko o ke keʻena hoʻokolohua, mai kahi ʻano hoʻokahi o nā pūnaewele immune immune. Hiki i kēia mau lāʻau ʻino ke hoʻomaopopo i nā mea ma nā hunaola maʻi ʻaʻai a i ʻole nā mea maʻamau e kōkua ai i nā hunaola maʻi ʻaʻai. Hoʻopili nā mea ʻino i nā mea a pepehi i nā hunaola maʻi ʻaʻai, ālai i ko lākou ulu ʻana, a i ʻole mālama iā lākou mai ka hoʻolaha ʻana. Hāʻawi ʻia nā antibodies Monoclonal e ka hoʻokomo. Hoʻohana wale ʻia lākou a i ʻole lawe i nā lāʻau, toxins, a i ʻole radioactive pono i nā hunaola maʻi ʻaʻai. ʻO Daratumumab a me elotuzumab nā monoclonal antibodies i hoʻohana ʻia i ka mālama ʻana i nā myeloma he nui a me nā neoplasms cell plasma ʻē aʻe. ʻO Denosumab kahi antibody monoclonal i hoʻohana ʻia e lohi i ka nalo ʻana o ka iwi a hoʻemi i ka ʻeha o ka iwi i nā mea maʻi me ka myeloma he nui.
- ʻO ka Histone deacetylase (HDAC) ka mea hoʻōla inhibitor: Kāki kēia lāʻau i nā ʻenemema e pono ai no ka mahele o ka cell a hiki ke hoʻopau i ka ulu ʻana o nā hunaola maʻi ʻaʻai. ʻO Panobinostat kahi mea kāohi iā HDAC i hoʻohana ʻia i ka mālama ʻana i nā myeloma he nui a me nā neoplasms pūnaewele plasma ʻē aʻe.
- Hoʻomaʻamaʻa BCL2 mea kāohi: Hoʻopaʻa kēia hana i kahi protein i kapa ʻia BCL2. Hiki ke kōkua i ka pale ʻana i kēia protein i ka make ʻana i nā hunaola maʻi ʻaʻaʻi a e hoʻomāhuahua iā lākou i nā lāʻau anticancer. ʻO Venetoclax kahi mea pāpā BCL2 e hoʻopaʻa ʻia i ka mālama ʻana i ka myeloma i hoʻi hou ʻia a i ʻole refactory.
E ʻike i nā lāʻau i ʻae ʻia no Myeloma maha a me nā Neoplasms Plasma Cell ʻē aʻe no ka ʻike hou aku.
ʻO ka chemotherapy kiʻekiʻe me ka transplant cell stem
Hāʻawi ʻia nā lāʻau kiʻekiʻe o ka chemotherapy e pepehi i nā hunaola maʻi ʻaʻai. Hoʻopau pū ʻia nā hunaola olakino, e like me nā hunaola koko, e ka lāʻau maʻi ʻaʻai. ʻO ka transplant cell Stem kahi lapaʻau e pani i nā hunaola koko. Lawe ʻia nā hunaola (ʻaʻa ʻole o ke koko) mai ke koko a i ʻole ka iwi o ka mea maʻi (autologous) a i ʻole he mea hāʻawi (allogeneic) a paʻa a waiho ʻia. Ma hope o ka pau ʻana o ka chemotherapy i ka mea hoʻomanawanui, hoʻoheheʻe ʻia nā pūnaewele i mālama ʻia a hoʻihoʻi ʻia i ka mea maʻi ma o ka infusion. E ulu kēia mau hunaola i (a hoʻihoʻi) i nā huna koko o ke kino.
Immunotherapy
ʻO ka Immunotherapy kahi lapaʻau e hoʻohana i ka ʻōnaehana pale maʻi o ka mea maʻi e hakakā i ka maʻi ʻaʻai. Hoʻohana ʻia nā mea i hana ʻia e ke kino a i hana ʻia paha i kahi keʻena hoʻokolohua e hoʻonui, kuhikuhi, a hoʻihoʻi hou i nā pale kūlohelohe o ke kino i ka maʻi ʻaʻai. Kāhea ʻia kēia ʻano lapaʻau maʻi ʻaʻai a biotherapy a i ʻole biologic therapy.
- Hoʻomaʻamaʻa Immunomodulator: ʻo Thalidomide, lenalidomide, a me pomalidomide he mau immunomodulator i hoʻohana ʻia e mālama i nā myeloma he nui a me nā neoplasms cell plasma ʻē aʻe.
- Interferon: Hoʻopili kēia hana i ka mahele o nā hunaola maʻi ʻaʻai a hiki ke hoʻolohi i ka ulu ʻana o ka tumo.
- CAR T-cell therapy: Hoʻololi kēia lapaʻau i nā hunaola T o ka mea maʻi (kahi ʻano o ke keʻena pale pale) no laila e hoʻouka lākou i kekahi mau protein i luna o nā hunaola maʻi ʻaʻai. Lawe ʻia nā pūnaewele T mai ka mea maʻi a hoʻohui ʻia nā mea loaʻa kūikawā i kā lākou ʻilikai i ka hale hana. Kapa ʻia nā hunaola i kapa ʻia he chimeric antigen receptor (CAR) nā pūnaewele T. Hoʻonui ʻia nā pūnaewele CAR T i loko o ke keʻena hoʻokolohua a hāʻawi ʻia i ka mea maʻi ma ka hoʻoulu ʻana. Hoʻonui nā ʻāpana CAR T i ke koko o ka mea maʻi a hoʻouka i nā hunaola maʻi ʻaʻai. Ke aʻo ʻia nei ʻo CAR T-cell therapy i ka mālama ʻana i nā myeloma maha i hoʻi hou (hoʻi mai).
E ʻike i nā lāʻau i ʻae ʻia no Myeloma maha a me nā Neoplasms Plasma Cell ʻē aʻe no ka ʻike hou aku.
Lapaʻau hoʻomākala
ʻO ka radiation radiation kahi lāʻau maʻi maʻi maʻi e hoʻohana i nā kukuna x nui ikaika a i ʻole nā ʻano radiation e hoʻomake i nā hunaola maʻi ʻaʻai a mālama ʻole paha i ka ulu ʻana. Hoʻohana ka radiation radiation kūwaho i kahi mīkini ma waho o ke kino e hoʻouna i ka radiation i kahi o ke kino me ka maʻi ʻaʻai.
ʻOki kino
Hiki ke hana i kahi ʻoki e wehe ai i ka tumo. Ma hope o ka hemo ʻana o ke kauka i nā maʻi ʻaʻai āpau i hiki ke ʻike ʻia i ka manawa o ke ʻoki ʻana, hiki i kekahi mau maʻi ke hāʻawi i ka radiation radiation ma hope o ke kaha ʻana e luku i nā hunaola maʻi ʻea i koe. ʻO ka lāʻau i hāʻawi ʻia ma hope o ke kaha ʻana, e hoʻohaʻahaʻa i ka makaʻu e hoʻi mai ka maʻi ʻaʻai, i kapa ʻia ʻo adjuvant therapy.
Ke kali kiaʻi nei
Ke kali nei ke kiaʻi me ka nānā pono ʻana i ke ʻano o ka mea maʻi me ka ʻole o ka hāʻawi ʻana i nā lāʻau a hiki i ka wā e ʻike ʻia ai nā hōʻailona a i ʻole nā loli.
Ke hoʻāʻo ʻia nei nā ʻano lapaʻau hou i nā hoʻokolohua hoʻokolohua.
Hōʻike kēia ʻāpana hōʻuluʻulu manaʻo i nā mālama e hoʻopaʻa ʻia nei i nā hoʻokolohua hoʻokolohua. ʻAʻole paha ia e ʻōlelo i kēlā me kēia lapaʻau hou e hoʻopaʻa ʻia ana. Loaʻa nā ʻike e pili ana i nā hoʻokolohua hoʻokolohua mai ka pūnaewele NCI.
Hoʻohui hou o nā therapies
Ke aʻo nei nā hoʻokolohua hoʻokolohua i nā hui like ʻole o ka immunotherapy, chemotherapy, steroid therapy, a me nā lāʻau. Ke aʻo ʻia nei nā regimens lapaʻau hou e hoʻohana ana i ka selinexor.
Hoʻomaʻamaʻa no nā neoplasms pūnaewele plasma i nā hopena ʻaoʻao.
No ka ʻike e pili ana i nā hopena i hopena ʻia e ka lapaʻau ʻana no ka maʻi ʻaʻai, e ʻike i kā mākou ʻaoʻao ʻaoʻao ʻaoʻao.
Hāʻawi ʻia ke kākoʻo kākoʻo e hōʻemi i nā pilikia i hoʻokumu ʻia e ka maʻi a i ʻole kāna mālama ʻana.
Mālama kēia therapy i nā pilikia a i ʻole nā hopena ʻē aʻe i hoʻokumu ʻia e ka maʻi a i ʻole kāna mālama ʻana, a hoʻomaikaʻi i ka maikaʻi o ke ola. Hāʻawi ʻia ke kākoʻo e mālama i nā pilikia i hoʻokumu ʻia e myeloma he nui a me nā neoplasms cell plasma ʻē aʻe.
Hoʻokomo ʻia ka mālama i kākoʻo i kēia mau mea:
- Plasmapheresis: Inā mānoanoa ke koko me nā protein antibody keu a keʻakeʻa i ka holo ʻana, hana ʻia ka plasmapheresis e hemo i nā plasma a me nā protein antibody hou mai ke koko. I kēia kaʻina hana ua lawe ʻia ke koko mai ka mea maʻi a hoʻouna ʻia ma o ka mīkini e hoʻokaʻawale i ka plasma (ka ʻāpana wai o ke koko) mai nā hunaola koko. Aia i ka plasma o ka mea maʻi ka maʻi pale ʻaʻohe e pono ai a hoʻi ʻia i ka mea maʻi. Hoʻihoʻi ʻia nā hunaola kūlohelohe i ke kahe o ke koko me ka plasma i hāʻawi ʻia a i ʻole kahi pani plasma. ʻAʻole mālama ʻo Plasmapheresis i nā antibodies hou mai ka hoʻokumu ʻana.
- ʻO ka chemotherapy kiʻekiʻe loa me ka transplant cell stem: inā hiki mai ka amyloidosis, hiki i ka mālama ʻana ke komo i ka chemotherapy me ka lāʻau kiʻekiʻe e ukali ʻia e ka transplant cell stem me ka hoʻohana ʻana i nā cell stem iho o ka mea maʻi.
- Immunotherapy: Hāʻawi ʻia ka Immunotherapy me thalidomide, lenalidomide, a i ʻole pomalidomide e mālama i ka amyloidosis.
- Hoʻolālā pahuhopu: hāʻawi ʻia ka lāʻau hoʻomāka ʻia me nā mea hoʻopale proteasome e hōʻemi i ka nui o ka immunoglobulin M i loko o ke koko a mālama iā amyloidosis Hāʻawi ʻia ka mea i hoʻomākaukau ʻia me ka antibody monoclonal e lohi i ka nalo ʻana o ka iwi a hoʻemi i ka ʻeha o ka iwi.
- ʻO ka radiation radiation: Hāʻawi ʻia ka radiation radiation no nā iwi o ka iwi kuamoʻo.
- Chemotherapy: Hāʻawi ʻia ʻo Chemotherapy e hōʻemi i ka ʻeha o ke kua mai ka osteoporosis a i ʻole nā haʻihaʻi o ke kuamoʻo.
- Hoʻoikaika Bisphosphonate: hāʻawi ʻia ka lāʻau Bisphosphonate e hoʻolohi i ka nalo ʻana o ka iwi a hoʻemi i ka ʻeha o ka iwi. E ʻike i nā hōʻuluʻulu e hiki mai ana no ka ʻike hou aku e pili ana i nā bisphosphonates a me nā pilikia e pili ana i kā lākou hoʻohana ʻana.
- ʻEha maʻi ʻaʻai
- Nā pilikia o ka waha o Chemotherapy a me ke kukui poʻo poʻo / ʻāʻī
Makemake paha nā mea maʻi e noʻonoʻo e pili ana i ka hoʻokolokolo ʻana.
No kekahi mau mea maʻi, ke komo nei i ka hoʻokolohua hoʻokolohua ke koho lapaʻau maikaʻi loa paha. ʻO nā hoʻokolohua hoʻokolohua kahi ʻāpana o ka noiʻi ʻana o ka maʻi ʻaʻai. Hana ʻia nā hoʻokolohua hoʻokolohua e ʻike inā palekana a maikaʻi a maikaʻi paha nā hoʻomaʻamaʻa maʻi ʻaʻai ma mua o ka maʻamau maʻamau.
ʻO ka hapa nui o nā hana maʻamau no ka maʻi ʻaʻai i kau ʻia ma nā hoʻokolohua hoʻokolohua mua. ʻO nā mea maʻi i komo i ka hoʻokolokolo hoʻokolohua hiki ke loaʻa i ka lāʻau maʻamau a i ʻole i waena o nā mea mua i loaʻa kahi lāʻau hou.
ʻO nā mea maʻi i komo i nā hoʻokolohua hoʻokolohua kōkua pū kekahi i ka hoʻomaikaʻi ʻana i ke ʻano o ka mālama ʻana i ka maʻi ʻaʻai i ka wā e hiki mai ana. ʻOiai ʻaʻole nā alakaʻi hoʻokolohua e alakaʻi i nā hoʻoponopono hou maikaʻi, pane pinepine lākou i nā nīnau nui a kōkua i ka neʻe i mua o ka noiʻi.
Hiki i nā mea maʻi ke komo i nā hoʻokolohua hoʻokolohua ma mua, i ka wā, a ma hope paha o ka hoʻomaka ʻana i kā lākou mālama maʻi ʻaʻai.
Hoʻopili wale kekahi mau hoʻokolohua hoʻokolohua i nā mea maʻi i loaʻa ʻole ka lapaʻau. ʻO nā hoʻokolohua ʻē aʻe e hōʻoia i nā mālama ʻana no ka poʻe maʻi i loaʻa ʻole ka maikaʻi o ka maʻi ʻaʻai. Aia kekahi mau hoʻokolohua hoʻokolohua e hoʻāʻo i nā ala hou e hōʻoki i ka maʻi ʻaʻai mai ka hoʻi hou ʻana (hoʻi ʻana) a hōʻemi paha i nā hopena o ka mālama ʻana i ka maʻi ʻaʻai.
Ke mālama ʻia nei nā hoʻokolohua hoʻokolohua ma nā wahi he nui o ka ʻāina. Hiki ke ʻike ʻia ka ʻike e pili ana i nā hoʻokolohua hoʻokolohua e kākoʻo ʻia e NCI ma ka pūnaewele ʻimi noiʻi hoʻokolohua a NCI. Hiki ke loaʻa nā hoʻokolohua hoʻokolohua i kākoʻo ʻia e nā hui ʻē aʻe ma ka pūnaewele ClinicalTrials.gov.
Pono paha nā hoʻokolohua ukali.
ʻO kekahi o nā hoʻokolohua i hana ʻia e hōʻoia i ka maʻi ʻaʻai a i ʻole e ʻike i ke kahua o ka maʻi ʻaʻaʻa e hana hou ʻia paha. E hana hou ʻia kekahi mau hōʻike i mea e ʻike ai i ka maikaʻi o ka mālama ʻana. Hoʻoholo ʻia nā hoʻoholo e pili ana inā e hoʻomau, hoʻololi, a kū paha i ka lāʻau ʻana ma nā hopena o kēia mau hoʻāʻo.
E hoʻomau ʻia kekahi o nā hoʻokolohua mai kēlā me kēia manawa ma hope o ka pau ʻana o ka lāʻau. Hiki i nā hopena o kēia mau hoʻāʻo ke hōʻike inā ua loli kou ʻano a i ʻole inā ua hoʻi hou ke kanesa. Kapa ʻia kēia mau hoʻāʻo i kekahi manawa nā hoʻokolohua ukali a i ʻole nā loiloi.
Hoʻomaʻamaʻa i ka Monoclonal Gammopathy o ka Undetermined Significance
No ka ʻike e pili ana i nā lāʻau i helu ʻia ma lalo, e ʻike i ka ʻaoʻao Overtion Option Overview.
ʻO ka mālama ʻana i ka gammopathy monoclonal o ke koʻikoʻi undetermined (MGUS) e kali kiaʻi mau ana. ʻO nā hoʻokolohua koko maʻamau e nānā i ke kiʻekiʻe o ka protein M i loko o ke koko a me nā hoʻokolohua kino e nānā no nā hōʻailona a me nā hōʻailona o ka maʻi ʻaʻai.
E hoʻohana i kā mākou ʻimi hoʻokolohua hoʻokolohua e ʻike i nā hoʻokolohua hoʻokolohua maʻi maʻi i kākoʻo ʻia e NCI e ʻae nei i nā mea maʻi. Hiki iā ʻoe ke ʻimi i nā hoʻāʻo e pili ana i ke ʻano o ka maʻi ʻaʻai, ka makahiki o ka mea hoʻomanawanui, a kahi e hana ʻia ai nā hoʻokolokolo. Loaʻa nā ʻike laulā e pili ana i nā hoʻokolohua hoʻokolohua.
Iapaau ana o kaʻawale Plasmacytoma o ka iwi
No ka ʻike e pili ana i nā lāʻau i helu ʻia ma lalo, e ʻike i ka ʻaoʻao Overtion Option Overview.
ʻO ka mālama ʻana i ka plasmacytoma kaʻawale o ka iwi ka hoʻomaʻamaʻa radiation radiation i ka leona iwi.
E hoʻohana i kā mākou ʻimi hoʻokolohua hoʻokolohua e ʻike i nā hoʻokolohua hoʻokolohua maʻi maʻi i kākoʻo ʻia e NCI e ʻae nei i nā mea maʻi. Hiki iā ʻoe ke ʻimi i nā hoʻāʻo e pili ana i ke ʻano o ka maʻi ʻaʻai, ka makahiki o ka mea hoʻomanawanui, a kahi e hana ʻia ai nā hoʻokolokolo. Loaʻa nā ʻike laulā e pili ana i nā hoʻokolohua hoʻokolohua.
Ka mālama ʻana iā Extramedullary Plasmacytoma
No ka ʻike e pili ana i nā lāʻau i helu ʻia ma lalo, e ʻike i ka ʻaoʻao Overtion Option Overview.
Hiki i ka mālama ʻana i ka plasmacytoma extramedullary ke hoʻopili i kēia mau mea:
- ʻO ka radiation radiation i ka puʻupuʻu a me nā kiko lymph kokoke.
- ʻOki kino, maʻa mau e radiation radiation.
- Ke kali nei ke kiaʻi ma hope o ka mālama mua ʻana, a ukali ʻia e ka radiation radiation, ʻoki kino, a chemotherapy paha ke ulu ka tumo a i ʻole ke kumu o nā hōʻailona a hōʻailona paha.
E hoʻohana i kā mākou ʻimi hoʻokolohua hoʻokolohua e ʻike i nā hoʻokolohua hoʻokolohua maʻi maʻi i kākoʻo ʻia e NCI e ʻae nei i nā mea maʻi. Hiki iā ʻoe ke ʻimi i nā hoʻāʻo e pili ana i ke ʻano o ka maʻi ʻaʻai, ka makahiki o ka mea hoʻomanawanui, a kahi e hana ʻia ai nā hoʻokolokolo. Loaʻa nā ʻike laulā e pili ana i nā hoʻokolohua hoʻokolohua.
Lapaʻau o Multiple Myeloma
No ka ʻike e pili ana i nā lāʻau i helu ʻia ma lalo, e ʻike i ka ʻaoʻao Overtion Option Overview.
ʻO nā mea maʻi me ka ʻole o nā hōʻailona a hōʻailona paha e pono ʻole e mālama. Hiki i kēia mau mea maʻi ke kiaʻi me ka kali a hiki i ka ʻike ʻia ʻana o nā hōʻailona.
Ke ʻike ʻia nā hōʻailona a i ʻole nā hōʻailona, ʻelua mau mahele no nā mea maʻi e loaʻa ana i ka lāʻau.
- ʻOi aku ka ʻōpio, kūpono i nā mea maʻi e kūpono i kahi transplant cell stem.
- ʻO nā mea maʻi ʻelemakule, kūpono ʻole i kūpono ʻole i kahi transplant cell stem.
ʻO nā mea maʻi ma mua o 65 mau makahiki e noʻonoʻo ʻia he ʻōpio a kūpono. ʻAʻole kūpono nā mea maʻi ma mua o 75 mau makahiki no kahi transplant cell stem. No nā mea maʻi ma waena o nā makahiki o 65 a me 75 mau makahiki, hoʻoholo ʻia ke olakino e ko lākou olakino holoʻokoʻa a me nā kumu ʻē aʻe.
Hana pinepine ʻia ka mālama ʻana i nā myeloma he nui i nā pae:
- Hoʻoponopono hoʻokomo : ʻO kēia ka pae mua o ka lapaʻau. ʻO kāna pahuhopu ka hōʻemi ʻana i ka nui o nā maʻi, a komo pū paha i hoʻokahi a ʻoi paha o kēia mau mea:
- No nā ʻōpio, kūpono i nā mea maʻi (kūpono i kahi transplant):
- ʻO Chemotherapy.
- Hoʻopaʻa kaulike ʻia me ka mea proteasome inhibitor (bortezomib).
- Immunotherapy (lenalidomide).
- Hoʻoikaika Corticosteroid.
- No nā mea ʻelemakule, kūpono ʻole (ʻaʻole kūpono i kahi transplant):
- ʻO Chemotherapy.
- Hoʻopaʻa kaulike ʻia me ka mea proteasome inhibitor (bortezomib a carfilzomib) a i ʻole kahi monoclonal antibody (daratumumab).
- Immunotherapy (lenalidomide).
- Hoʻoikaika Corticosteroid.
- Hoʻohui chemotherapy: ʻO kēia ka lua o ka pae o ka lapaʻau. ʻO ka mālama ʻana i ke kaʻina hoʻohui e pepehi i nā hunaola maʻi ʻē aʻe. ʻO ka chemotherapy kiʻekiʻe loa e ukali ʻia e kekahi:
- hoʻokahi transplant cell stem autologous, kahi e hoʻohana ʻia ai nā hunaola o ka mea maʻi mai ke koko a i ʻole ka iwi iwi; a i ʻole
- ʻelua transplants puʻupuʻu autologous ukali ʻia e kahi autologous a i ʻole allogeneic ʻōiwi transplant, kahi e loaʻa ai i ka mea maʻi ka maʻi o ke koko a i ʻole ka iwi iwi o kahi mea hāʻawi a i ʻole
- hoʻokahi transplant cell allogeneic koʻokoʻo.
- Hoʻomaʻamaʻa mālama: Ma hope o ka hana mua, hāʻawi pinepine ʻia ka mālama mālama e kōkua i ka mālama ʻana i ka maʻi no kahi manawa lōʻihi. Ke aʻo ʻia nei kekahi mau ʻano lapaʻau no kēia hoʻohana, me kēia mau mea:
- ʻO Chemotherapy.
- Immunotherapy (interferon a i ʻole lenalidomide).
- Hoʻoikaika Corticosteroid.
- Hoʻopaʻa kaulike ʻia me ka mea proteasome inhibitor (bortezomib a i ʻole ixazomib).
E hoʻohana i kā mākou ʻimi hoʻokolohua hoʻokolohua e ʻike i nā hoʻokolohua hoʻokolohua maʻi maʻi i kākoʻo ʻia e NCI e ʻae nei i nā mea maʻi. Hiki iā ʻoe ke ʻimi i nā hoʻāʻo e pili ana i ke ʻano o ka maʻi ʻaʻai, ka makahiki o ka mea hoʻomanawanui, a kahi e hana ʻia ai nā hoʻokolokolo. Loaʻa nā ʻike laulā e pili ana i nā hoʻokolohua hoʻokolohua.
Hoʻomaʻamaʻa i ka Releled or Refractory Multiple Myeloma
No ka ʻike e pili ana i nā lāʻau i helu ʻia ma lalo, e ʻike i ka ʻaoʻao Overtion Option Overview.
Hoʻomaʻamaʻa ʻia ka myeloma hou a i ʻole refactory mau myeloma i kēia mau mea:
- Ke kali nei no ka poʻe maʻi i kūpaʻa ko lākou maʻi.
- ʻO kahi lapaʻau ʻokoʻa ma mua o ka mālama ʻana i hāʻawi ʻia, no nā mea maʻi i ulu pinepine ka tumo i ka wā o ka lapaʻau. (E ʻike i nā koho lapaʻau Myeloma maha.)
- Hoʻohana ʻia nā lāʻau like i hoʻohana ʻia ma mua o ka hoʻihoʻi hou ʻana inā kū ka relaps i hoʻokahi a ʻoi paha mau makahiki ma hope o ka lapaʻau mua. (E ʻike i nā koho lapaʻau Myeloma maha.)
Hoʻohana ʻia nā lāʻau i hoʻohana ʻia i kēia mau mea:
- Hoʻopaʻa kaulike ʻia me nā antibodies monoclonal (daratumumab a i ʻole elotuzumab).
- Hoʻopaʻa kaulike ʻia me nā mea hoʻopale proteasome (bortezomib, carfilzomib, a i ʻole ixazomib).
- Immunotherapy (pomalidomide, lenalidomide, a i ʻole thalidomide).
- ʻO Chemotherapy.
- ʻO Histone deacetylase mea kāohi lāʻau lapaʻau me panobinostat.
- Hoʻoikaika Corticosteroid.
- ʻO kahi hoʻokolohua hoʻokolohua o CAR T-cell therapy.
- ʻO ka hoʻāʻo hoʻokolohua ʻana o ka lāʻau i hoʻomākaukau ʻia me kahi mea mole mole mole liʻiliʻi (selinexor) a me ka hoʻōla kino.
- ʻO kahi hoʻokolohua hoʻokolohua o ka lāʻau hoʻomākaukau ʻia me kahi mea hōʻoki BCL2 (venetoclax).
E hoʻohana i kā mākou ʻimi hoʻokolohua hoʻokolohua e ʻike i nā hoʻokolohua hoʻokolohua maʻi maʻi i kākoʻo ʻia e NCI e ʻae nei i nā mea maʻi. Hiki iā ʻoe ke ʻimi i nā hoʻāʻo e pili ana i ke ʻano o ka maʻi ʻaʻai, ka makahiki o ka mea hoʻomanawanui, a kahi e hana ʻia ai nā hoʻokolokolo. Loaʻa nā ʻike laulā e pili ana i nā hoʻokolohua hoʻokolohua.
E aʻo hou aʻe e pili ana i nā Neoplasms Plasma Cell
No ka ʻike hou aku mai ka National Cancer Institute e pili ana i ka myeloma he nui a me nā neoplasms cell plasma ʻē aʻe, e ʻike i ka mea aʻe:
- ʻO Myeloma Multiple / ʻĀpana Plasma Cell Neoplasms Home ʻaoʻao
- Ua ʻae ʻia nā lāʻau no Multiple Myeloma a me nā Neoplasms Plasma Cell ʻē aʻe
- ʻO nā Therapy Cancer i kau ʻia
- ʻO nā Transplant Cell-Blood Stem
- Immunotherapy e mālama i ka maʻi ʻaʻai
No ka ʻike ākea maʻi ʻaʻai a me nā kumuwaiwai ʻē aʻe mai ka National Cancer Institute, e ʻike i ka mea aʻe:
- E pili ana i ka maʻi ʻaʻai
- Ke hoʻokū nei
- ʻO Chemotherapy a ʻo ʻoe: Kākoʻo no ka poʻe me ka maʻi ʻaʻai
- Radiation Therapy a ʻo ʻoe: Kākoʻo no ka poʻe me ka maʻi ʻaʻai
- Ke kāohi nei i ka maʻi ʻaʻai
- Nā nīnau e nīnau ai i kāu kauka e pili ana i ka maʻi ʻaʻai
- No nā mea ola a me nā mea mālama
E hoʻohā i ka ʻōlelo hoʻohou auto-refresher