Nā ʻano / lymphoma / hoʻomanawanui / mycosis-fungoides-lapaʻau-pdq

Mycosis Fungoides (Me Sézary Syndrome) Hoʻomaʻamaʻa (®) –Patient Version

Nā ʻIkepili Nui e pili ana i Mycosis Fungoides (Me Sézary Syndrome)

NA MANA KUNI

• ʻO nā mycosis fungoides a me Sézary Syndrome he mau maʻi kahi e lilo ai nā lymphocytes (kahi ʻano o ke koko koko keʻokeʻo) i mea hōʻino (maʻi ʻaʻai) a hoʻopili i ka ʻili.

• ʻO Mycosis fungoides a me Sézary syndrome kahi ʻano o ka lymphoma T-cell cutaneus.

• ʻO kahi hōʻailona o mycosis fungoides kahi ʻulaʻula ma ka ʻili.

• I ka maʻi Sézary, loaʻa nā maʻi T-maʻi i ke koko.

• Hoʻohana ʻia nā hoʻokolohua e nānā i ka ʻili a me ke koko e ʻike i nā mycosis fungoides a me Sézary Syndrome.

• Kū kekahi mau kumu i ka wānana (kahi o ke ola ʻana) a me nā koho lapaʻau.

ʻO nā mycosis fungoides a me Sézary Syndrome he mau maʻi kahi e lilo ai nā lymphocytes (kahi ʻano o ke koko koko keʻokeʻo) i mea hōʻino (maʻi ʻaʻai) a hoʻopili i ka ʻili.

ʻO ka maʻamau, hana ka iwi o ka iwi i nā hunaola koʻokoʻo (nā puʻupuʻu ʻole) i lilo i mau puʻupuʻu koko oʻo makua i ka manawa. Hiki i ke kinipōpō kūpoko ke lilo i cell cell myeloid a i ʻole ka cell stem lymphoid. Lilo kahi sela myeloid i ʻula koko ʻulaʻula, keʻokeʻo koko keʻokeʻo, a i ʻole platelet. Lilo ke kinipōpō lymphoid i lymphoblast a laila kekahi o ʻekolu mau ʻano lymphocytes (nā keʻokeʻo koko keʻokeʻo):

• ʻO nā limfosit B-cell e hana i nā mea pale e kōkua i ke kaua ʻana i ka maʻi.

• ʻO nā lymphocytes T-cell e kōkua i nā B-lymphocytes e hana i nā mea pale i kōkua i ke kaua ʻana i ka maʻi.

• ʻO nā hunaola kūlohelohe e hoʻouka aku i nā hunaola maʻi ʻaʻai a me nā virus.

Hoʻonui ulu kino. Hele ke aʻa koʻokoʻo koko i nā ʻanuʻu he nui e lilo i ʻulaʻula koko, platelet, a i ʻole ke koko keʻokeʻo.

I ka mycosis fungoides, lilo ʻo T-cell lymphocytes i maʻi ʻaʻai a hoʻopili i ka ʻili. Ke kū kēia mau lymphocytes i ke koko, ua kapa ʻia lākou he mau huna ʻo Sézary. I ka Sézary syndrome, hoʻopili nā lymphocytes T-cell i ka ʻili a loaʻa nā nui o nā huna Sézary i ke koko.

ʻO Mycosis fungoides a me Sézary syndrome kahi ʻano o ka lymphoma T-cell cutaneus.

ʻO Mycosis fungoides a me Sézary Syndrome nā ʻano maʻamau ʻelua o ka limahana limahana T-cell (kahi ʻano o ka lymphoma non-Hodgkin). No ka ʻike e pili ana i nā ʻano ʻē aʻe o ka maʻi ʻaʻai ʻili a i ʻole ka lymphoma non-Hodgkin, e ʻike i nā hōʻuluʻulu aʻe:

• ʻO ka mālama ʻana i ka Lymphoma Non-Hodgkin makua

• ʻIli maʻi ʻaʻai ʻili

• Mālama ʻo Melanoma

• Hoʻomaʻo Kaposi Sarcoma

ʻO kahi hōʻailona o mycosis fungoides kahi ʻulaʻula ma ka ʻili.

Hiki i nā mycosis fungoides ke hele i nā ʻano aʻe:

• Māhele Premycotic: Kahi wīwī, ʻulaʻula i nā wahi o ke kino i hōʻike ʻole ʻia i ka lā. ʻAʻole kumu kēia ʻōpala i mau ʻōuli a mau paha i mau mahina a mau makahiki paha. He paʻakikī ke kuhi i ka hū e like me ka mycosis fungoides i kēia wā.

• Patch phase: Nani, ʻulaʻula, eczema-like wīwī.

• Kahi pae: ʻO nā puʻupuʻu i hoʻokiʻiliʻi ʻia (papules) a i ʻole nā ​​ʻāʻī paʻakikī i ka ʻili, i ʻulaʻula ʻia paha.

• Tumor phase: Kū nā tumors ma ka ʻili. Hiki i kēia mau puʻupuʻu ke hoʻomohala i nā maʻi puʻupuʻu a hiki i ka ʻili ke maʻi.

E nīnau me kāu kauka inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona.

I ka maʻi Sézary, loaʻa nā maʻi T-maʻi i ke koko.

Eia kekahi, ʻulaʻula ka ʻili a puni ke kino, ʻili, ʻili, a ʻeha hoʻi. Hiki paha i nā pākuʻi, nā pā, a me nā tumors ma ka ʻili. ʻAʻole ʻike ʻia inā ʻo Sézary Syndrome kahi ʻano holomua o ka mycosis fungoides a i ʻole kahi maʻi ʻokoʻa.

Hoʻohana ʻia nā hoʻokolohua e nānā i ka ʻili a me ke koko e ʻike i nā mycosis fungoides a me Sézary Syndrome.

Hiki ke hoʻohana ʻia nā hoʻāʻo a me nā kaʻina hana aʻe:

• ʻO ka hoʻāʻo kino a me ka mōʻaukala olakino: kahi hōʻike o ke kino e nānā i nā hōʻailona laulā o ke olakino, e like me ka nānā ʻana i nā hōʻailona o ka maʻi, e like me nā puʻupuʻu, ka helu a me ke ʻano o nā ʻili leona, a i ʻole nā ​​mea ʻē aʻe e ʻano ʻē. ʻO nā kiʻi o ka ʻili a me ka mōʻaukala o ke olakino olakino * ʻano maʻamau a me nā maʻi i hala a me nā mālama ʻana e kiʻi pū ʻia.

• Helu piha i ke koko me ka ʻokoʻa: kahi hana e huki ʻia ai kahi laʻana o ke koko a nānā ʻia no kēia mau mea:

• ʻO ka helu o nā hunaola ʻulaʻula a me nā platelet.

• ʻO ka helu a me ke ʻano o nā hunaola keokeo.

• ʻO ka nui o ka hemoglobin (ka protein i hāpai i ka oxygen) i loko o nā hunaola ʻulaʻula.

• ʻO ka ʻāpana o ka hāpana koko i hana ʻia i nā hunaola ʻulaʻula.

Helu piha ke koko (CBC). Hōʻiliʻili ʻia ke koko ma ka hoʻokomo ʻana i kahi nila i loko o kahi aa a ʻae i ke kahe o ke koko i loko o kahi paipu. Hoʻouna ʻia ka laʻana koko i ke keʻena hoʻokolohua a helu ʻia nā ʻulaʻula o ke koko, nā hunaola keokeo, a me nā platelet. Hoʻohana ʻia ka CBC e hoʻāʻo ai, e hōʻoia ai, a nānā i nā ʻano like ʻole.

• Helu helu ʻāpana koko Sézary: Kahi hana e ʻike ʻia ai kahi laʻana o ke koko ma lalo o kahi microscope e helu ai i nā helu Sézary.

• Hoʻāʻo HIV: He hōʻike e ana i ke kiʻekiʻe o nā maʻi ʻino HIV i kahi hāpana o ke koko. Hana ʻia nā Antibodies e ke kino ke hoʻouka ʻia e kahi waiwai haole. ʻO ke kiʻekiʻe o nā mea ʻino HIV he mea paha ua maʻi ka maʻi i ka maʻi HIV.

• ʻO ka biopsy o ka ʻili: ka hemo ʻana o nā hunaola a i ʻole nāʻaʻaʻa i hiki iā lākou ke nānā ma lalo o kahi microscope e nānā ai i nā hōʻailona o ka maʻi ʻaʻai. Hiki i ke kauka ke wehe i kahi ulu mai ka ʻili, kahi e nānā ʻia e kahi pathologist. ʻOi aku paha i kahi biopsy ʻili e pono ai e hōʻoia i nā mycosis fungoides. Nā hoʻokolohua ʻē aʻe i hiki ke hana ʻia ma nā pūnaewele a i ʻole ka laʻana pūnaewele e like me kēia:

• Immunophenotyping: kahi hoʻokolohua hoʻokolohua e hoʻohana ai i nā mea ʻino e ʻike ai i nā hunaola maʻi ʻaʻai e pili ana i nā ʻano antigens a i ʻole nā ​​māka ma ka ʻili o nā hunaola. Hoʻohana ʻia kēia ho'āʻo e kōkua i ke kuhi ʻana i nā ʻano kikoʻī o ka lymphoma.

• Kahe uila ʻili pūnaewele. Hoʻopili ʻia nā hunaola mai kahi hāpana o ke koko o ka mea maʻi, ka iwi o ka iwi, a i ʻole nā ​​mea ʻē aʻe me ka pena wai fluorescent, waiho ʻia i loko o kahi wai, a laila hele kekahi i hoʻokahi manawa i ke kaola o ke kukui. Hoʻokumu ʻia nā hopena o ka hoʻāʻo e pili ana i ka hopena o nā hunaola i hoʻohuehue ʻia me ka pena fluorescent i ke kaola o ke kukui. Hoʻohana ʻia kēia hoʻokolohua e kōkua i ke kuhi a mālama ʻana i kekahi ʻano o nā maʻi ʻaʻai, e like me leukemia a me lymphoma.

• Hōʻike hoʻāʻo moʻomeheu hoʻāʻo T-cell (TCR): Hōʻike kahi keʻena hoʻokolohua kahi e nānā ʻia ai nā hunaola i loko o kahi kiko o ke koko a i ʻole ka iwi iwi e ʻike inā aia kekahi mau loli i nā ʻāpana e hana i nā mea loaʻa ma nā hunaola T (ʻulaʻula keokeo). Hiki i nā hoʻāʻo ʻana no kēia mau hoʻololi ʻana o ka ʻāpana ke haʻi inā paha e hana ʻia nā helu nui o nā pūnaewele T me kahi receptor T-cell.

Kū kekahi mau kumu i ka wānana (kahi o ke ola ʻana) a me nā koho lapaʻau.

Pili ka wānana a me nā koho lapaʻau i kēia mau mea:

• Ke kahua o ka maʻi ʻaʻai.

• Ke ʻano o ka leona (nā pāliki, nā pā, a me nā tumors).

• ʻO ka makahiki o ka mea hoʻomanawanui a me kāna kāne.

ʻO ka mycosis fungoides a me Sézary Syndrome paʻakikī e hoʻōla. ʻO ka maʻamau maʻamau ka palliative, e hōʻoluʻolu i nā hōʻailona a hoʻomaikaʻi i ka maikaʻi o ke ola. ʻO nā mea maʻi me ka maʻi pae mua e ola i mau makahiki.

Nā kahua o Mycosis Fungoides (Me Sézary Syndrome)

NA MANA KUNI

• Ma hope o ka loaʻa ʻana o ka mycosis fungoides a me Sézary Syndrome, hana ʻia nā hoʻokolohua e ʻike inā ua hoʻolaha ʻia nā hunaola maʻi maʻi mai ka ʻili i nā ʻāpana ʻē aʻe o ke kino.

• ʻEkolu ala e hoʻolaha ai ka maʻi ʻaʻai i loko o ke kino.

• E laha paha ka maʻi ʻaʻai mai kahi i hoʻomaka ai i nā ʻāpana ʻē aʻe o ke kino.

• Hoʻohana ʻia nā pae aʻe no ka mycosis fungoides a me Sézary Syndrome:

• ʻOihana I Mycosis Fungoides

• ʻOihana Fungoides Mycosis kahua II

• ʻOihana III Mycosis Fungoides

• ʻOihana IV Mycosis Fungoides / Sézary Syndrome

Ma hope o ka loaʻa ʻana o ka mycosis fungoides a me Sézary Syndrome, hana ʻia nā hoʻokolohua e ʻike inā ua hoʻolaha ʻia nā hunaola maʻi maʻi mai ka ʻili i nā ʻāpana ʻē aʻe o ke kino.

ʻO ke kaʻina hana e ʻike inā ua pālahalaha ka maʻi ʻaʻai mai ka ʻili i nā ʻāpana ʻē aʻe o ke kino i kapa ʻia he staging. ʻO ka ʻikepili i hōʻiliʻili ʻia mai ke kaʻina hana e hoʻoholo ai i ka pae o ka maʻi. He mea nui ia e ʻike i ke kahua i mea e hoʻolālā ai i ka lāʻau.

Hiki ke hoʻohana ʻia nā kaʻina hana aʻe i ke kaʻina hana.

• ʻO ke kukui x: kahi x-ray o nā mea a me nā iwi i loko o ka umauma. ʻO ka x-ray kahi ʻano kukuna ikehu e hiki ke hele ma waena o ke kino a ma ke kiʻi ʻoniʻoni, e hana ana i kiʻi o nā wahi i loko o ke kino.

• CT scan (CAT scan): Kahi hana e hana ai i kahi o nā kiʻi kikoʻī o nā wahi i loko o ke kino, e like me nā lymph node, ka umauma, ʻōpū, a me nā pelvis, i lawe ʻia mai nā ʻaoʻao ʻokoʻa. Hana ʻia nā kiʻi e kahi kamepiula i hoʻopili ʻia i kahi mīkini x-ray. Hoʻokomo ʻia paha ke kala i loko o ke aa a i ʻole ale ʻia e kōkua i nā ʻōpū a i ʻole nā ​​kino i hōʻike hou aku me ka maopopo. Kāhea ʻia kēia kaʻina hana he tomography i helu ʻia, kamepiula tomography, a i ʻole he tomography axial computerized.

• PET scan (positron emission tomography scan): kahi hana e loaʻa ai nā puʻupuʻu tumo malignant i loko o ke kino. Hoʻokomo ʻia kahi liʻiliʻi o ka glucose radioactive (kō) i loko o kahi aa koko. Hoʻopili ka scanner PET a puni ke kino a hana i kahi kiʻi o kahi e hoʻohana ʻia ai ka glucose i ke kino. ʻOi aku ka mālamalama o nā hunaola tumo ma ke kiʻi no ka mea ʻoi aku ka hana a lawe i ka glucose ma mua o ka hana ʻana o nā hunaola maʻamau.

• ʻO ka biopsy Lymph node: Ka lawe ʻana o nā mea āpau a ʻāpana paha o kahi kōpona lymph. ʻIke kahi pathologist i ke kiko o ka lymph node ma lalo o kahi microscope e nānā ai i nā hunaola maʻi ʻaʻai.

• ʻO ka ʻiʻo o ka iwi iwi a me ka biopsy: Ka lawe ʻia ʻana o ka iwi iwi a me kahi ʻāpana o ka iwi ma ka hoʻokomo ʻana i kahi nila kuha i loko o ka hipbone a i ʻole ka umauma. ʻIke kahi pathologist i ka momona o ka iwi a me ka iwi ma lalo o kahi microscope e nānā i nā hōʻailona o ka maʻi ʻaʻai.

ʻEkolu ala e hoʻolaha ai ka maʻi ʻaʻai i loko o ke kino.

Hiki ke pālahalaha ʻia ka maʻi ʻaʻai ma o nā meaola, ka ʻōnaehana lymph, a me ke koko.

• Kāpena. Hoʻolahalaha ka maʻi ʻaʻai mai kahi i hoʻomaka ai i ka ulu ʻana i nā wahi kokoke.

• ʻŌnaehana Lymph. Hoʻolahalaha ka maʻi ʻaʻai mai kahi i hoʻomaka ai i ke komo ʻana i ka ʻōnaehana lymph. Hele ka maʻi ʻaʻai ma o nā kīʻaha lymph i nā ʻāpana ʻē aʻe o ke kino.

• Koko. Hoʻolahalaha ka maʻi ʻaʻai mai kahi i hoʻomaka ai i ke komo ʻana i ke koko. Hele ka maʻi ʻaʻai ma o nā kīʻaha koko i nā ʻāpana ʻē aʻe o ke kino.

E laha paha ka maʻi ʻaʻai mai kahi i hoʻomaka ai i nā ʻāpana ʻē aʻe o ke kino.

Ke pālahalaha ʻia ka maʻi ʻaʻai i kekahi ʻāpana o ke kino, ua kapa ʻia ia ʻo metastasis. E haki nā hunaola maʻi 'aʻai mai kahi a lākou i hoʻomaka ai (ka tumo mua) a hele i loko o ka ʻōnaehana lymph a i ʻole ke koko.

ʻŌnaehana Lymph. Komo ka maʻi ʻaʻai i loko o ka ʻōnaehana lymph, hele ma waena o nā kīʻaha lymph, a hana i kahi tumo (tumo metastatic) i kekahi ʻāpana o ke kino.

Koko. Komo ke kanesa i loko o ke koko, hele ma waena o nā kīʻaha koko, a hana i kahi tumo (tumo metastatic) i kekahi ʻāpana o ke kino. ʻO ka tumo metastatic ka ʻano like o ke kanesa me ka tumo mua. ʻO kahi laʻana, inā pāhola ka mycosis fungoides i ke akepaʻa, ʻo nā hunaola maʻi ʻaʻai i loko o ke akepaʻa he mycosis fungoides cells. ʻO ka maʻi he metastatic mycosis fungoides, ʻaʻole ka maʻi ʻaʻai ate.

Hoʻohana ʻia nā pae aʻe no ka mycosis fungoides a me Sézary Syndrome:

ʻOihana I Mycosis Fungoides

Māhele ʻia ka pae I i nā pae IA a me IB penei:

• ʻAnuʻu IA: Pākuʻi, papule, a me / a i ʻole nā ​​pākuʻi e uhi ma lalo o 10% o ka ʻili.

• ʻOihana IB: Pākuʻi, papule, a me / a i ʻole nā ​​pākuʻi e uhi iā 10% a ʻoi paha o ka ʻili.

• Aia paha he helu haʻahaʻa o nā hunaola Sézary i ke koko.

ʻOihana Fungoides Mycosis kahua II

Māhele ʻia ka pae II i nā pae IIA a me IIB penei:

• Hana IIA: Pākuʻi, papule, a me / a i ʻole nā ​​pākuʻi e uhi i ka nui o ka ʻili. ʻAʻole maʻamau nā lymph node, akā ʻaʻole lākou he maʻi maʻi.

• Kahua IIB: Hoʻokahi a ʻoi aku paha o nā tumors i ʻoi aku ma ka ʻili o 1 centimeter a ʻoi aku. He mea maʻamau ʻole nā ​​lymph nodes, akā ʻaʻole lākou he maʻi maʻi.

Aia paha he helu haʻahaʻa o nā hunaola Sézary i ke koko.

ʻOihana III Mycosis Fungoides

I ke kahua III, 80% a ʻoi paha o ka ʻili i ʻulaʻula a loaʻa paha i nā palaki, papule, pālolo, a me nā tumors. He mea maʻamau ʻole nā ​​lymph nodes, akā ʻaʻole lākou he maʻi maʻi.

Aia paha he helu haʻahaʻa o nā hunaola Sézary i ke koko.

ʻOihana IV Mycosis Fungoides / Sézary Syndrome

Ke loaʻa ka helu kiʻekiʻe o nā hunaola Sézary i ke koko, kapa ʻia ka maʻi ʻo Sézary Syndrome.

Māhele ʻia ka pae IV i nā pae IVA1, IVA2, a me IVB penei:

• Kahua IVA1: Pākuʻi, papula, pālolo, a i ʻole nā ​​tumors i uhi i kekahi nui o ka ʻili, a 80% a ʻoi paha o ka ʻili i ʻulaʻula. He mea maʻamau ʻole nā ​​lymph nodes, akā ʻaʻole maʻi maʻi maʻi. Aia kekahi helu kiʻekiʻe o nā hunaola Sézary i ke koko.

• Kahua IVA2: Pākuʻi, papula, pāka, a i ʻole nā ​​tumors i uhi i kekahi nui o ka ʻili, a 80% a ʻoi paha o ka ʻili i ʻulaʻula. He mea maʻamau ʻole nā ​​lymph node, a i ʻole hoʻokumu ʻia ka maʻi ʻaʻai i loko o nā pūnana lymph. Aia paha he helu kiʻekiʻe o nā hunaola Sézary i ke koko.

• ʻOihana IVB: Ua pālahalaha ʻia ka maʻi ʻaʻai i nā mea ʻē aʻe i loko o ke kino, e like me ka pelupelu a me ke akepaʻa. Hiki i nā pākuʻi, nā papula, nā pā, a i ʻole nā ​​tumors ke uhi i kekahi nui o ka ʻili, a ʻulaʻula paha ka 80% a ʻoi paha o ka ʻili. Kūleʻa a maʻi ʻaʻai paha nā lymph nodes. Aia paha he helu kiʻekiʻe o nā hunaola Sézary i ke koko.

Laulā Manaʻo Option Oponopono

NA MANA KUNI

• Aia nā ʻano lapaʻau like ʻole no nā mea maʻi me ka mycosis fungoides a me ka maʻi ʻaʻai Sézary maʻi maʻi.

• Hoʻohana ʻia ʻehiku ʻano o ka mālama maʻamau.

• Hoʻoikaika Photodynamic

• Lapaʻau hoʻomākala

• ʻO Chemotherapy

• Laau lāʻau ʻē aʻe

• Immunotherapy

• Pahuhopu kau ʻia

• ʻO ka chemotherapy kiʻekiʻe a me ka radiation radiation me ka transplant cell stem

• Ke hoʻāʻo ʻia nei nā ʻano lapaʻau hou i nā hoʻokolohua hoʻokolohua.

• ʻO ka mālama ʻana no ka mycosis fungoides a me Sézary syndrome ke kumu o ka hopena.

• Makemake paha nā mea maʻi e noʻonoʻo e pili ana i ka hoʻokolokolo ʻana.

• Hiki i nā mea maʻi ke komo i nā hoʻokolohua hoʻokolohua ma mua, i ka wā, a ma hope paha o ka hoʻomaka ʻana i kā lākou mālama maʻi ʻaʻai.

• Pono paha nā hoʻokolohua ukali.

Aia nā ʻano lapaʻau like ʻole no nā mea maʻi me ka mycosis fungoides a me ka maʻi ʻaʻai Sézary maʻi maʻi.

Loaʻa nā ʻano lapaʻau like ʻole no nā mea maʻi me ka mycosis fungoides a me Sézary Syndrome. Kūlana maʻamau kekahi mau hōʻailona (ʻo ka lāʻau i hoʻohana ʻia i kēia manawa), a ʻo kekahi e hoʻāʻo ʻia nei i nā hoʻokolohua hoʻokolohua. ʻO kahi hoʻokolohua hoʻokolohua lapaʻau kahi noiʻi noiʻi i manaʻo ʻia e kōkua i ka hoʻomaikaʻi ʻana i nā mālama ʻana i kēia manawa a i ʻole loaʻa ka ʻike e pili ana i nā mālama hou no nā maʻi me ka maʻi ʻaʻai. Ke hōʻike nā hoʻokolohua hoʻokolohua ʻoi aku ka maikaʻi o kahi lapaʻau hou ma mua o ka maʻamau maʻamau, lilo paha ka lāʻau hou i ka lapaʻau maʻamau. Makemake paha nā mea maʻi e noʻonoʻo e pili ana i ka hoʻokolokolo ʻana. ʻO kekahi mau hoʻokolohua hoʻokolohua e hāmama wale i nā mea maʻi i hoʻomaka ʻole i ka lāʻau.

Hoʻohana ʻia ʻehiku ʻano o ka mālama maʻamau.

Hoʻoikaika Photodynamic

ʻO Photodynamic therapy kahi lāʻau lapaʻau i hoʻohana i ka lāʻau lapaʻau a me kekahi ʻano o ke kukui laser e pepehi i nā hunaola maʻi ʻaʻai. ʻO kahi lāʻau e hana ʻole a hiki i ka wā e hōʻike ʻia i ka mālamu e hoʻopili ʻia i loko o kahi aa koko. Hōʻiliʻili ka lāʻau i nā mea maʻi ʻaʻai ma mua o nā hunaola maʻamau. No ka maʻi ʻaʻai ʻili, hoʻomālamalama ka kukui laser i ka ʻili a lilo ka lāʻau i mea hana a make i nā hunaola maʻi ʻaʻai. Hoʻomaʻamaʻa ka lāʻau Photodynamic i ka hōʻemi iki ʻana i nā mea olakino ʻO nā mea maʻi e mālama ana i ka lāʻau photodynamic therapy e pono e kaupalena i ka nui o ka manawa i lilo i ka lā. Aia nā ʻano like ʻole o ka photodynamic therapy:

• I ka psoralen a me ka ultraviolet A (PUVA) therapy, loaʻa i ka mea maʻi ka lāʻau i kapa ʻia psoralen a laila ultraviolet A kuhikuhi ʻia ka radiation i ka ʻili.

• I ka extracorporeal photochemotherapy, hāʻawi ʻia ka mea maʻi i nā lāʻau a laila lawe ʻia kekahi mau huna koko mai ke kino, waiho ʻia ma lalo o kahi kukui ultraviolet A kūikawā, a hoʻihoʻi ʻia i loko o ke kino. Hiki ke hoʻohana ʻia ʻo Extracorporeal photochemotherapy wale a hui ʻia paha me ka huina uila uila (TSEB) radiation radiation.

Lapaʻau hoʻomākala

ʻO ka radiation radiation kahi lāʻau maʻi maʻi maʻi e hoʻohana i nā kukuna x nui ikaika a i ʻole nā ​​ʻano radiation e hoʻomake i nā hunaola maʻi ʻaʻai a mālama ʻole paha i ka ulu ʻana. Hoʻohana ka radiation radiation kūwaho i kahi mīkini ma waho o ke kino e hoʻouna i ka radiation i kahi o ke kino me ka maʻi ʻaʻai. I kekahi manawa, hoʻohana ʻia ka radiation radiation uila (TSEB) radiation radiation e mālama i nā mycosis fungoides a me Sézary Syndrome. ʻO kēia kahi ʻano o ka mālama ʻana i ka pāhawewe i waho kahi e pahuhopu ai ka mīkini radiation radiation i nā electrons (nā liʻiliʻi, ʻike ʻole ʻia o nā huna huna) ma ka ʻili e uhi ana i ke kino holoʻokoʻa. Hiki ke hoʻohana ʻia ka radiation radiation kūwaho ma ke ʻano he palliative therapy e hōʻoluʻolu ai i nā ʻōuli a hoʻomaikaʻi i ka maikaʻi o ke ola.

Hāʻawi ʻia ʻo Ultraviolet A (UVA) radiation radiation a i ʻole ultraviolet B (UVB) radiation radiation me ka hoʻohana ʻana i kahi kukui kūikawā a i ʻole ka kukuna e kuhikuhi ana i ka pāhawewe ma ka ʻili.

ʻO Chemotherapy

ʻO Chemotherapy kahi lāʻau lapaʻau maʻi maʻi e hoʻohana i nā lāʻau e hōʻoki i ka ulu ʻana o nā hunaola maʻi ʻaʻai, ma ka luku ʻana i nā hunaola a i ʻole ke kāpae ʻana iā lākou mai ka hoʻokaʻawale. Ke lawe ʻia ka chemotherapy e ka waha a i ʻole injected i loko o kahi aa koko a i ʻole nā ​​mākala, komo nā lāʻau i ke kahe o ke koko a hiki ke kiʻi i nā hunaola maʻi ʻōpio i loko o ke kino (chemotherapy ʻōnaehana). I kekahi manawa he kumuhana ka chemotherapy (kau i ka ʻili i ka kirimalu, ʻoki, a me ka hamo).

E ʻike i nā lāʻau i ʻae ʻia no Non-Hodgkin Lymphoma no ka ʻike hou aku. (Mycosis fungoides a me Sézary Syndrome kekahi ʻano o ka non-Hodgkin lymphoma.)

Laau lāʻau ʻē aʻe

Hoʻohana ʻia nā corticosteroids kumuhana e hoʻonā i ka ʻulaʻula, pehu, a me ka ʻili i hoʻā ʻia. He ʻano steroid lākou. ʻO nā corticosteroids kumuhana paha i loko o ka kirimalu, ʻona, a hamo paha.

ʻO Retinoids, e like me bexarotene, nā lāʻau e pili ana i ka wikamina A i hiki ke hoʻolohi i ka ulu ʻana o kekahi ʻano o nā hunaola maʻi ʻaʻai. Lawe ʻia paha nā retinoids e ka waha a i ʻole hoʻokomo i ka ʻili.

ʻO Lenalidomide kahi lāʻau e kōkua i ka ʻōnaehana pale e pepehi i nā hunaola kūlohelohe a i ʻole nā ​​pūnaʻi maʻi ʻaʻaʻi a pale paha i ka ulu ʻana o nā kīʻaha koko e pono ai e ulu nā tumors

ʻO Vorinostat a me romidepsin ʻelua o nā mea kāohi histone deacetylase (HDAC) i hoʻohana ʻia e mālama i ka mycosis fungoides a me Sézary syndrome. Hoʻololi nā mea pāpā ʻo HDAC i kahi loli kemika e hōʻoki ana i nā pūnaewele tumora mai ka hoʻokaʻawale ʻana.

E ʻike i nā lāʻau i ʻae ʻia no Non-Hodgkin Lymphoma no ka ʻike hou aku. (Mycosis fungoides a me Sézary Syndrome kekahi ʻano o ka non-Hodgkin lymphoma.)

Immunotherapy

ʻO ka Immunotherapy kahi lapaʻau e hoʻohana i ka ʻōnaehana pale maʻi o ka mea maʻi e hakakā i ka maʻi ʻaʻai. Hoʻohana ʻia nā mea i hana ʻia e ke kino a i hana ʻia paha i kahi keʻena hoʻokolohua e hoʻonui, kuhikuhi, a hoʻihoʻi hou i nā pale kūlohelohe o ke kino i ka maʻi ʻaʻai. Kāhea ʻia kēia ʻano lapaʻau maʻi ʻaʻai a biotherapy a i ʻole biologic therapy.

• Interferon: hoʻopilikia kēia lapaʻau me ka mahele o ka mycosis fungoides a me nā huna Sézary a hiki ke hoʻolohi i ka ulu ulu.

E ʻike i nā lāʻau i ʻae ʻia no Non-Hodgkin Lymphoma no ka ʻike hou aku. (Mycosis fungoides a me Sézary Syndrome kekahi ʻano o ka non-Hodgkin lymphoma.)

Pahuhopu kau ʻia

ʻO ka therapy target kahi ʻano lapaʻau e hoʻohana i nā lāʻau a i ʻole nā ​​mea ʻē aʻe e hoʻouka aku i nā hunaola maʻi ʻaʻai. Hoʻolālā pinepine nā mea i hoʻomākaukau ʻia i ka hōʻemi ʻana i nā hunaola maʻamau ma mua o ka chemotherapy a i ʻole radiation radiation.

• Monoclonal antibody therapy: hoʻohana kēia hana i nā mea pale i hana ʻia i loko o ke keʻena hoʻokolohua mai kahi ʻano hoʻokahi o ka pūnaewele immune system. Hiki i kēia mau lāʻau ʻino ke hoʻomaopopo i nā mea ma nā hunaola maʻi ʻaʻai a i ʻole nā ​​mea maʻamau e kōkua ai i nā hunaola maʻi ʻaʻai. Hoʻopili nā mea ʻino i nā mea a pepehi i nā hunaola maʻi ʻaʻai, ālai i ko lākou ulu ʻana, a i ʻole mālama iā lākou mai ka hoʻolaha ʻana. Hoʻohana wale ʻia lākou a i ʻole lawe i nā lāʻau, toxins, a i ʻole radioactive pono i nā hunaola maʻi ʻaʻai. Hāʻawi ʻia nā antibodies Monoclonal e ka hoʻokomo.

Nā ʻano o nā antibodies monoclonal:

• ʻO Brentuximab vedotin, kahi i loaʻa i kahi antibody monoclonal e hoʻopili ai i kahi protein, i kapa ʻia ʻo CD30, i loaʻa ma kekahi ʻano o nā pūnaʻi lymphoma. Loaʻa iā ia kahi lāʻau anticancer i hiki ke kōkua i ka luku ʻana i nā hunaola maʻi ʻaʻai.

• ʻO Mogamulizumab, kahi i loaʻa i kahi antibody monoclonal e hoʻopili ana i kahi protein, i kapa ʻia ʻo CCR4, i loaʻa ma kekahi ʻano o nā pūnaʻi lymphoma. Hiki iā ia ke ālai i kēia protein a kōkua i ka ʻōnaehana pale ʻole e luku i nā hunaola maʻi ʻaʻai. Hoʻohana ʻia ia e mālama i nā mycosis fungoides a me Sézary Syndrome i hoʻi mai a i ʻole hoʻi i maikaʻi ʻole ma hope o ka lapaʻau ʻana me ka liʻiliʻi ma hoʻokahi o ka systemic therapy.

ʻO ka chemotherapy kiʻekiʻe a me ka radiation radiation me ka transplant cell stem

Hāʻawi ʻia nā lāʻau kiʻekiʻe o ka chemotherapy a me kekahi manawa i ka radiation therapy e pepehi i nā hunaola maʻi ʻaʻai. Hoʻopau pū ʻia nā hunaola olakino, e like me nā hunaola koko, e ka lāʻau maʻi ʻaʻai. ʻO ka transplant cell Stem kahi lapaʻau e pani i nā hunaola koko. Lawe ʻia nā hunaola ʻōpala (ʻaʻaʻa ʻole o ke koko) mai ke koko a i ʻole ka iwi o ka mea maʻi a i ʻole he mea hāʻawi a hoʻopaʻa ʻia a mālama ʻia. Ma hope o ka hoʻopau ʻana o ka mea hoʻomanawanui i ka chemotherapy a me ka radiation therapy, hoʻoheheʻe ʻia nā pūnaewele i mālama ʻia a hoʻihoʻi ʻia i ka mea maʻi ma o ka infusion. E ulu kēia mau hunaola i (a hoʻihoʻi) i nā huna koko o ke kino.

Ke hoʻāʻo ʻia nei nā ʻano lapaʻau hou i nā hoʻokolohua hoʻokolohua.

Loaʻa nā ʻike e pili ana i nā hoʻokolohua hoʻokolohua mai ka pūnaewele NCI.

ʻO ka mālama ʻana no ka mycosis fungoides a me Sézary syndrome ke kumu o ka hopena.

No ka ʻike e pili ana i nā hopena i hopena ʻia e ka lapaʻau ʻana no ka maʻi ʻaʻai, e ʻike i kā mākou ʻaoʻao ʻaoʻao ʻaoʻao.

Makemake paha nā mea maʻi e noʻonoʻo e pili ana i ka hoʻokolokolo ʻana.

No kekahi mau mea maʻi, ke komo nei i ka hoʻokolohua hoʻokolohua ke koho lapaʻau maikaʻi loa paha. ʻO nā hoʻokolohua hoʻokolohua kahi ʻāpana o ka noiʻi ʻana o ka maʻi ʻaʻai. Hana ʻia nā hoʻokolohua hoʻokolohua e ʻike inā palekana a maikaʻi a maikaʻi paha nā hoʻomaʻamaʻa maʻi ʻaʻai ma mua o ka maʻamau maʻamau.

ʻO ka hapa nui o nā hana maʻamau no ka maʻi ʻaʻai i kau ʻia ma nā hoʻokolohua hoʻokolohua mua. ʻO nā mea maʻi i komo i ka hoʻokolokolo hoʻokolohua hiki ke loaʻa i ka lāʻau maʻamau a i ʻole i waena o nā mea mua i loaʻa kahi lāʻau hou.

ʻO nā mea maʻi i komo i nā hoʻokolohua hoʻokolohua kōkua pū kekahi i ka hoʻomaikaʻi ʻana i ke ʻano o ka mālama ʻana i ka maʻi ʻaʻai i ka wā e hiki mai ana. ʻOiai ʻaʻole nā ​​alakaʻi hoʻokolohua e alakaʻi i nā hoʻoponopono hou maikaʻi, pane pinepine lākou i nā nīnau nui a kōkua i ka neʻe i mua o ka noiʻi.

Hiki i nā mea maʻi ke komo i nā hoʻokolohua hoʻokolohua ma mua, i ka wā, a ma hope paha o ka hoʻomaka ʻana i kā lākou mālama maʻi ʻaʻai.

Hoʻopili wale kekahi mau hoʻokolohua hoʻokolohua i nā mea maʻi i loaʻa ʻole ka lapaʻau. ʻO nā hoʻokolohua ʻē aʻe e hōʻoia i nā mālama ʻana no ka poʻe maʻi i loaʻa ʻole ka maikaʻi o ka maʻi ʻaʻai. Aia kekahi mau hoʻokolohua hoʻokolohua e hoʻāʻo i nā ala hou e hōʻoki i ka maʻi ʻaʻai mai ka hoʻi hou ʻana (hoʻi ʻana) a hōʻemi paha i nā hopena o ka mālama ʻana i ka maʻi ʻaʻai.

Ke mālama ʻia nei nā hoʻokolohua hoʻokolohua ma nā wahi he nui o ka ʻāina. Hiki ke ʻike ʻia ka ʻike e pili ana i nā hoʻokolohua hoʻokolohua e kākoʻo ʻia e NCI ma ka pūnaewele ʻimi noiʻi hoʻokolohua a NCI. Hiki ke loaʻa nā hoʻokolohua hoʻokolohua i kākoʻo ʻia e nā hui ʻē aʻe ma ka pūnaewele ClinicalTrials.gov.

Pono paha nā hoʻokolohua ukali.

ʻO kekahi o nā hoʻokolohua i hana ʻia e hōʻoia i ka maʻi ʻaʻai a i ʻole e ʻike i ke kahua o ka maʻi ʻaʻaʻa e hana hou ʻia paha. E hana hou ʻia kekahi mau hōʻike i mea e ʻike ai i ka maikaʻi o ka mālama ʻana. Hoʻoholo ʻia nā hoʻoholo e pili ana inā e hoʻomau, hoʻololi, a kū paha i ka lāʻau ʻana ma nā hopena o kēia mau hoʻāʻo.

E hoʻomau ʻia kekahi o nā hoʻokolohua mai kēlā me kēia manawa ma hope o ka pau ʻana o ka lāʻau. Hiki i nā hopena o kēia mau hoʻāʻo ke hōʻike inā ua loli kou ʻano a i ʻole inā ua hoʻi hou ke kanesa. Kapa ʻia kēia mau hoʻāʻo i kekahi manawa nā hoʻokolohua ukali a i ʻole nā ​​loiloi.

Mālama i ke kahua I a me ka pae II Mycosis Fungoides

No ka ʻike e pili ana i nā lāʻau i helu ʻia ma lalo, e ʻike i ka ʻaoʻao Overtion Option Overview.

ʻO ka mālama ʻana i ka pae I a me ka pae II mycosis fungoides hou aʻe paha e like me kēia:

• ʻO Psoralen a me ultraviolet A (PUVA) radiation radiation.

• ʻO Ultraviolet B radiation therapy.

• Pāhawewe me ka huila ʻili uila uila uila. I kekahi mau hihia, hāʻawi ʻia ka radiation radiation i nā lehelehe o ka ʻili, e like me ka palliative therapy e hōʻemi ai i ka nui o ka tumo e hōʻoluʻolu ai i nā ʻōuli a hoʻomaikaʻi i ke ola.

• Hāʻawi wale ʻia ʻo Immunotherapy a i hui ʻia paha me ka lāʻau i kuhikuhi ʻia i ka ʻili.

• ʻO ka chemotherapy kumuhana.

• ʻO ka chemotherapy ʻōnaehana me hoʻokahi a ʻoi paha nā lāʻau, i hiki ke hoʻohui ʻia me ka lāʻau i kuhikuhi ʻia i ka ʻili.

• ʻO nā lāʻau lapaʻau ʻē aʻe (corticosteroids kumuhana, retinoid therapy, lenalidomide, histone deacetylase inhibitors).

• Hoʻolālā pahuhopu (brentuximab vedotin).

E hoʻohana i kā mākou ʻimi hoʻokolohua hoʻokolohua e ʻike i nā hoʻokolohua hoʻokolohua maʻi maʻi i kākoʻo ʻia e NCI e ʻae nei i nā mea maʻi. Hiki iā ʻoe ke ʻimi i nā hoʻāʻo e pili ana i ke ʻano o ka maʻi ʻaʻai, ka makahiki o ka mea hoʻomanawanui, a kahi e hana ʻia ai nā hoʻokolokolo. Loaʻa nā ʻike laulā e pili ana i nā hoʻokolohua hoʻokolohua.

Hana i ke kahua III a me ka pae IV Mycosis Fungoides (me Sézary Syndrome)

No ka ʻike e pili ana i nā lāʻau i helu ʻia ma lalo, e ʻike i ka ʻaoʻao Overtion Option Overview.

ʻO ka mālama ʻana i ka hanana III hou a me ka pae IV mycosis fungoides me Sézary Syndrome he palliative (e hōʻoluʻolu i nā ʻōuli a hoʻomaikaʻi i ka maikaʻi o ke ola) a hiki ke hoʻopili ʻia i kēia mau mea:

• ʻO Psoralen a me ultraviolet A (PUVA) radiation radiation.

• ʻO Ultraviolet B radiation therapy.

• Hāʻawi wale ʻia a hui pū ʻia paha me ka huakaʻi uila uila uila uila.

• Pāhawewe me ka huila ʻili uila uila uila. I kekahi mau hihia, hāʻawi ʻia ka radiation radiation i nā lehelehe o ka ʻili, e like me ka palliative therapy e hōʻemi ai i ka nui o ka tumo e hōʻoluʻolu ai i nā ʻōuli a hoʻomaikaʻi i ke ola.

• Hāʻawi wale ʻia ʻo Immunotherapy a i hui ʻia paha me ka lāʻau i kuhikuhi ʻia i ka ʻili.

• ʻO ka chemotherapy ʻōnaehana me hoʻokahi a ʻoi paha nā lāʻau, i hiki ke hoʻohui ʻia me ka lāʻau i kuhikuhi ʻia i ka ʻili.

• ʻO ka chemotherapy kumuhana.

• ʻO nā lāʻau lapaʻau ʻē aʻe (corticosteroids kumuhana, lenalidomide, bexarotene, histone deacetylase inhibitors).

• Hoʻopaʻa kaulike ʻia me ka brentuximab vedotin.

E hoʻohana i kā mākou ʻimi hoʻokolohua hoʻokolohua e ʻike i nā hoʻokolohua hoʻokolohua maʻi maʻi i kākoʻo ʻia e NCI e ʻae nei i nā mea maʻi. Hiki iā ʻoe ke ʻimi i nā hoʻāʻo e pili ana i ke ʻano o ka maʻi ʻaʻai, ka makahiki o ka mea hoʻomanawanui, a kahi e hana ʻia ai nā hoʻokolokolo. Loaʻa nā ʻike laulā e pili ana i nā hoʻokolohua hoʻokolohua.

Hoʻomaʻamaʻa i nā Mycosis Fungoides hou (me Sézary Syndrome)

No ka ʻike e pili ana i nā lāʻau i helu ʻia ma lalo, e ʻike i ka ʻaoʻao Overtion Option Overview.

Ua hoʻi hou nā mycosis fungoides a me Sézary Syndrome i ka ʻili a i ʻole nā ​​ʻāpana ʻē aʻe o ke kino ma hope o ka mālama ʻia ʻana.

ʻO ka mālama ʻana i nā fungoides mycosis hou me Sézary Syndrome paha i loko o kahi hoʻokolohua hoʻokolohua a hoʻopili pū paha i kēia:

• Pāhawewe me ka huila ʻili uila uila uila. I kekahi mau hihia, hāʻawi ʻia ka radiation radiation i nā ʻili o ka ʻili ma ke ʻano he palliative therapy e hōʻemi i ka nui o ka tumo e hōʻoluʻolu ai i nā ʻōuli a hoʻomaikaʻi i ke ola.

• ʻO Psoralen a me ultraviolet A (PUVA) radiation therapy, i hiki ke hāʻawi ʻia me ka immunotherapy.

• Pāhawewe ʻo Ultraviolet B.

• Extracorporeal photochemotherapy.

• ʻO ka chemotherapy ʻōnaehana me hoʻokahi a ʻoi paha nā lāʻau.

• ʻO nā lāʻau lapaʻau ʻē aʻe (corticosteroids kumuhana, retinoid therapy, lenalidomide, histone deacetylase inhibitors).

• Hāʻawi wale ʻia ʻo Immunotherapy a i hui ʻia paha me ka lāʻau i kuhikuhi ʻia i ka ʻili.

• ʻO ka chemotherapy kiʻekiʻe, a i kekahi manawa ka radiation therapy, me ka transplant cell stem.

• Hoʻolālā pahuhopu (brentuximab vedotin a mogamulizumab).

E hoʻohana i kā mākou ʻimi hoʻokolohua hoʻokolohua e ʻike i nā hoʻokolohua hoʻokolohua maʻi maʻi i kākoʻo ʻia e NCI e ʻae nei i nā mea maʻi. Hiki iā ʻoe ke ʻimi i nā hoʻāʻo e pili ana i ke ʻano o ka maʻi ʻaʻai, ka makahiki o ka mea hoʻomanawanui, a kahi e hana ʻia ai nā hoʻokolokolo. Loaʻa nā ʻike laulā e pili ana i nā hoʻokolohua hoʻokolohua.

E aʻo hou e pili ana i ka Mycosis Fungoides a me Sézary Syndrome

No ka ʻike hou aku mai ka National Cancer Institute e pili ana i ka mycosis fungoides a me Sézary syndrome, e ʻike i ka mea aʻe:

• ʻAoʻao Home Lymphoma

• Photodynamic Therapy no ka maʻi ʻaʻai

• Ua ʻae ʻia nā lāʻau no Non-Hodgkin Lymphoma

• Immunotherapy e mālama i ka maʻi ʻaʻai

• ʻO nā Therapy Cancer i kau ʻia

No ka ʻike ākea maʻi ʻaʻai a me nā kumuwaiwai ʻē aʻe mai ka National Cancer Institute, e ʻike i ka mea aʻe:

• E pili ana i ka maʻi ʻaʻai

• Ke hoʻokū nei

• ʻO Chemotherapy a ʻo ʻoe: Kākoʻo no ka poʻe me ka maʻi ʻaʻai

• Radiation Therapy a ʻo ʻoe: Kākoʻo no ka poʻe me ka maʻi ʻaʻai

• Ke kāohi nei i ka maʻi ʻaʻai

• Nā nīnau e nīnau ai i kāu kauka e pili ana i ka maʻi ʻaʻai

• No nā mea ola a me nā mea mālama