Types/soft-tissue-sarcoma/patient/child-soft-tissue-treatment-pdq

Jiyya mai laushi na Sarcoma na yara ( –) –Shafin haƙuri

Janar Bayani Game da Softarfin Softarƙashin Childhoodarfin Yara Sarcoma

MAGANAN MAGANA

• Yarinya mai laushi sarcoma cuta ce wacce a cikin ƙwayoyin cuta masu larura (kansar) suke samarwa a cikin laushin jiki.

• Sarkar sarcoma mai laushi yana faruwa a cikin yara da manya.

• Samun wasu cututtuka da cututtukan gado na iya ƙara haɗarin sarcoma nama mai taushi.

• Mafi sanannen alamar yara mai laushi sarcoma shine dunƙulen mara zafi ko kumburi a cikin kyallen takarda mai laushi na jiki.

• Ana amfani da gwaje-gwajen bincike don gano (samo) da kuma gano sarcoma mai taushi na yara.

• Idan gwaje-gwaje ya nuna akwai yiwuwar akwai sarcoma mai taushi, ana yin biopsy.

• Akwai nau'ikan daban-daban na sarcomas masu taushi.

• Fat nama

• Kashi da guringuntsi

• Fibrous (connective) nama marurai

• Ciwan jijiyoyin tsoka

• Muscleananan ƙwayoyin tsoka

• Abinda ake kira fibrohistiocytic marurai

• Jijiyoyin jijiyoyin jikin mutum

• Pericytic (Perivascular) ƙari

• Umumurji waɗanda ba a san asalinsu ba

• Ciwan jijiyoyin jini

• Wasu dalilai suna tasiri hangen nesa (damar dawowa) da zaɓuɓɓukan magani.

Yarinya mai laushi sarcoma cuta ce wacce a cikin ƙwayoyin cuta masu larura (kansar) suke samarwa a cikin laushin jiki.

Tissuesirji masu laushi na jiki suna haɗuwa, tallafi, da kewaye sauran sassan jiki da gabobi. Naman mai taushi sun hada da masu zuwa:

• Kitse.

• Haɗuwa da ƙashi da guringuntsi.

• Fibrous nama.

• Tsoka.

• Jijiyoyi

• Tendons (sassan nama masu haɗa tsokoki zuwa ƙashi).

• Abubuwan haɗin synovial (kyallen takarda kusa da haɗin gwiwa)

• Maganin jini.

• Lymph tasoshin.

Za a iya samun sarcoma mai taushi ko'ina a cikin jiki. A cikin yara, ciwace-ciwacen suna zama mafi yawa a cikin hannu, ƙafa, kirji, ko ciki.

Formsarƙirar sarcoma mai laushi a cikin ƙwayoyin jiki masu laushi, gami da tsoka, jijiyoyi, kitse, jijiyoyin jini, jijiyoyin lymph, jijiyoyi, da nama a kewayen mahaɗa.

Sarkar sarcoma mai laushi yana faruwa a cikin yara da manya.

Sarcoma mai laushi a cikin yara na iya amsawa daban-daban ga magani, kuma yana iya samun kyakkyawar magana fiye da sarcoma mai laushi a cikin manya. (Dubi taƙaitaccen bayanin game da Maganin carjin Sarcoma na Adult mai laushi don bayani game da magani a cikin manya.)

Samun wasu cututtuka da cututtukan gado na iya ƙara haɗarin sarcoma nama mai taushi.

Duk wani abu da zai kara maka hadarin kamuwa da cuta to ana kiran sa mai hadari. Samun haɗari ba ya nufin cewa za ku kamu da cutar kansa; ba tare da haɗarin abubuwan haɗari ba yana nufin cewa ba zaku sami cutar kansa ba. Yi magana da likitan ɗanka idan kana tunanin ɗanka na cikin haɗari.

Abubuwa masu haɗari ga sarcoma nama mai laushi yara sun haɗa da ciwon rikice-rikice masu zuwa:

• Ciwon Li-Fraumeni.

• Adenomatous polyposis na iyali (FAP).

• Canjin RB1 ya canza.

• SMARCB1 (INI1) canjin canjin yanayi.

• Neurofibromatosis nau'in 1 (NF1).

• Ciwon Werner.

• Kwayar cuta ta tubes.

• Adenosine mai raunin rashin ƙarfi mai haɗuwa rashin ƙarfi.

Sauran abubuwan haɗarin sun haɗa da masu zuwa:

• Maganin da ya gabata tare da maganin radiation.

• Samun kanjamau (wanda aka samu ciwo na rashin garkuwar jiki) da kamuwa da cutar Epstein-Barr a lokaci guda.

Mafi sanannen alamar yara mai laushi sarcoma shine dunƙulen mara zafi ko kumburi a cikin kyallen takarda mai laushi na jiki.

Sarcoma na iya bayyana kamar dunƙulen mara zafi a ƙarƙashin fata, galibi akan hannu, ƙafa, kirji, ko ciki. Maiyuwa babu wasu alamu ko alamomi a farko. Yayinda sarcoma ya kara girma ya danna kan gabobin da ke kusa, jijiyoyi, tsokoki, ko jijiyoyin jini, yana iya haifar da alamu ko alamomi, kamar ciwo ko rauni.

Sauran yanayi na iya haifar da alamu iri ɗaya. Binciki likitan ɗanka idan ɗanka yana da ɗayan waɗannan matsalolin.

Ana amfani da gwaje-gwajen bincike don gano (samo) da kuma gano sarcoma mai taushi na yara.

Za a iya amfani da waɗannan gwaje-gwajen da hanyoyin:

• Jarabawa ta jiki da tarihi: Jarabawa ce ta jiki don bincika alamomin lafiya gaba ɗaya, gami da bincika alamun cuta, kamar kumburi ko wani abu da kamar baƙon abu. Za a kuma ɗauki tarihin al'adun lafiyar marasa lafiya da cututtukan da suka gabata da magunguna.

• X-rays: X-ray wani katako ne na katako wanda zai iya ratsa jiki zuwa fim, yana yin hotunan wurare a cikin jiki.

• MRI (hoton maganadisu ): Hanya ce wacce take amfani da maganadisu, raƙuman rediyo, da kuma kwamfuta don yin jerin hotunan hotuna na sassan jiki, kamar kirji, ciki, hannu, ko ƙafa. Wannan hanya ana kiranta kuma ana kiranta hoton maganadisu na maganadisu (NMRI).

Hanyoyin fuska ta maganadisu (MRI) na ciki. Yaron yana kwance a kan tebur wanda yake zamewa cikin sikanin MRI, wanda ke ɗaukar hotunan cikin jiki. Kushin da ke jikin yaron yana taimaka wajan bayyana hotunan a bayyane.

• CT scan (CAT scan): Hanya ce da ke yin jerin hotuna dalla-dalla na wurare a cikin jiki, kamar kirji ko ciki, wanda aka ɗauka daga kusurwa daban-daban. Ana yin hotunan ne ta wata kwamfuta da aka haɗa ta da na'urar da ke ɗauke da x-ray. Ana iya yin allurar fenti a cikin jijiya ko haɗiye don taimakawa gabobin ko kyallen takarda su fito fili karara. Wannan hanya ana kiranta yanayin ƙididdigar lissafi, ƙirar kwamfuta, ko ƙirar ƙwaƙwalwar ajiyar kwamfuta.

Utedididdigar hoto (CT) na ciki. Yaron yana kwance a kan tebur wanda yake zamewa ta cikin na'urar daukar hoto na CT, wanda ke ɗaukar hotunan x-ray na cikin ciki.

• Gwajin duban dan tayi: Hanya ce wacce ake fitar da igiyar sauti mai karfi (duban dan tayi) daga kyallen ciki ko gabobin ciki kuma suna yin kuwwa. Eararrawa ta haifar da hoton kayan jikin da ake kira sonogram. Ana iya buga hoton don a kalleshi daga baya.

Idan gwaje-gwaje ya nuna akwai yiwuwar akwai sarcoma mai taushi, ana yin biopsy.

Nau'in biopsy ya dogara ne, a wani sashi, akan girman taro kuma ko yana kusa da saman fata ko yana da zurfi a cikin ƙwayar. Ofayan nau'ikan biopsies yawanci ana amfani dasu:

• Kwayar biopsy mai mahimmanci: Cire ƙwayar nama ta amfani da allura mai faɗi. Ana ɗaukar samfurin nama da yawa. Ana iya jagorantar wannan aikin ta amfani da duban dan tayi, CT scan, ko MRI.

• Gwajin Injial: Cire wani ɓangare na dunƙule ko samfurin nama.

• Exisional biopsy: Cire duka dunƙulen ko yanki na nama wanda ba shi da kyau. Kwararren likitan kwalliya yana kallon naman a ƙarƙashin madubin likita don neman ƙwayoyin kansa. Ana iya amfani da biopsy na cirewa don cire ƙanana marurai waɗanda ke kusa da fuskar fata. Irin wannan biopsy ba safai ake amfani da shi ba saboda kwayoyin kansar na iya kasancewa bayan biopsy. Idan kwayoyin cutar kansa suka rage, kansar na iya dawowa ko ta yada zuwa sauran sassan jiki.

Ana yin MRI na ƙari a gaban biopsy na cirewa. Ana yin wannan don nuna inda asalin kumburin ya samo kuma ana iya amfani dashi don jagorantar tiyata a nan gaba ko kuma maganin fitila.

Idan za ta yiwu, likitan da zai cire duk wani kumburi da aka samu ya kamata ya kasance cikin tsara biopsy. Sanya allurai ko raɗaɗɗen biopsy na iya shafar ko za a iya cire duka kumburin yayin aikin tiyata daga baya.

Don tsara mafi kyawun magani, samfurin nama da aka cire yayin nazarin halittu dole ne ya zama ya isa sosai don gano nau'in sarcoma mai laushi da yin wasu gwaje-gwaje na dakin gwaje-gwaje. Za'a ɗauki samfurorin nama daga asalin ƙwayar cuta, ƙwayoyin lymph, da sauran yankuna waɗanda ke da ƙwayoyin cutar kansa. Kwararren likitan kwalliya yana kallon naman a karkashin madubin likita don neman kwayoyin cutar kansa da kuma gano nau’i da matsayin marurai. Matsayin ciwace-ciwacen ƙwayar cuta ya dogara da yadda ƙwayoyin ƙwayoyin cuta ba su da kyau a ƙarƙashin madubin likita da kuma saurin yaduwar ƙwayoyin. Babban ciwayi da tsakiyar aji yawanci suna girma kuma suna yaduwa cikin sauri fiye da ƙananan ƙwayoyin cuta.

Saboda sarcoma mai laushi na iya zama da wuya a iya ganowa, ya kamata a duba samfurin nama ta hanyar likitan kwalliya wanda ke da kwarewa a bincikar sarcoma mai taushi.

Oraya ko fiye daga cikin gwaje-gwajen gwaje-gwaje masu zuwa ana iya yin don nazarin samfuran nama:

• Gwajin kwayoyin halitta: Gwajin gwaje-gwaje don bincika wasu ƙwayoyin halitta, sunadarai, ko wasu ƙwayoyin a cikin samfurin nama, jini, ko wani ruwan jiki. Ana iya yin gwajin kwayoyin tare da wasu hanyoyin, kamar su biopsies, don taimakawa wajen gano wasu nau'o'in na cutar kansa. Gwajin kwayoyin yana bincika wasu kwayar halitta ko canjin chromosome da ke faruwa a cikin wasu sarcomas ɗin taushi.

• Reverse transcription-polymerase chain reaction (RT-PCR): Gwajin gwaje-gwaje wanda aka auna yawan kwayar halittar da ake kira mRNA da aka kera ta wata kwayar halitta. Ana amfani da enzyme da ake kira transcriptase mai jujjuya don juya takamaiman yanki na RNA zuwa madaidaicin yanki na DNA, wanda za'a iya faɗaɗa shi (wanda aka yi shi da adadi mai yawa) ta wani enzyme mai suna DNA polymerase. Copiesididdigar DNA ɗin da aka faɗaɗa sun taimaka gaya ko ana yin takamaiman mRNA ta hanyar kwayar halitta. Ana iya amfani da RT – PCR don bincika kunna wasu ƙwayoyin halitta waɗanda na iya nuna kasancewar ƙwayoyin kansa. Ana iya amfani da wannan gwajin don neman wasu canje-canje a cikin kwayar halitta ko chromosome, wanda na iya taimakawa wajen gano cutar kansa.

• Nazarin Cytogenetic: Gwajin gwaje-gwaje wanda aka kirga chromosomes na ƙwayoyin cuta a cikin samfurin ƙwayar ƙwayar cuta kuma an bincika su don kowane canje-canje, kamar karye, ɓacewa, sake gyarawa, ko ƙarin ƙwayoyin cuta. Canje-canje a cikin wasu chromosomes na iya zama alamar cutar kansa. Ana amfani da nazarin Cytogenetic don taimakawa gano cutar kansa, shirya magani, ko gano yadda magani ke aiki. Haskewa a cikin yanayin haɓakawa (FISH) wani nau'in bincike ne na ilimin cytogenetic.

• Immunocytochemistry: Gwajin gwaje-gwaje wanda ke amfani da kwayoyin cuta don bincika wasu antigens (alamomi) a cikin samfurin ƙwayoyin marasa lafiya. Magungunan rigakafi yawanci suna da alaƙa da enzyme ko fenti mai kyalli. Bayan kwayoyin sun hada da antigen a cikin kwayoyin sel din, sai a kunna enzyme ko rini, sannan za a iya ganin antigen a karkashin madubin likita. Ana iya amfani da irin wannan gwajin don faɗi bambanci tsakanin nau'ikan sarcoma mai taushi.

• Haske da microscopy na lantarki: Gwajin dakin gwaje-gwaje wanda ake kallon kwayoyi a cikin samfurin nama a karkashin na'uran microscopes na yau da kullun don neman wasu canje-canje a cikin ƙwayoyin.

Akwai nau'ikan daban-daban na sarcomas masu taushi.

Kwayoyin kowane irin sarcoma suna da banbanci a karkashin madubin hangen nesa. An haɗu da ƙwayoyin cuta mai laushi bisa ga nau'in ƙwayoyin nama mai laushi inda suka fara kirkira.

Wannan taƙaitaccen bayani game da nau'ikan abubuwa masu laushi sarcoma:

Fat nama

Liposarcoma. Wannan ciwon daji ne na ƙwayoyin mai. Liposarcoma yawanci yakan zama a cikin mai mai ƙarkashin fata. A cikin yara da matasa, liposarcoma galibi ba shi da daraja (mai yiwuwa ya yi girma kuma ya faɗa a hankali). Akwai nau'ikan liposarcoma daban-daban, gami da:

• Myxoid liposarcoma. Wannan yawanci ƙananan ƙananan ciwon daji ne wanda ke amsawa da kyau ga magani.

• Pleomorphic liposarcoma. Wannan yawanci shine babban ciwon kansa wanda ba zai iya amsawa sosai ga magani ba.

Kashi da guringuntsi

Kashi da cututtukan guringuntsi sune cakuda ƙwayoyin ƙashi da ƙwayoyin guringuntsi. Kashi da cututtukan guringuntsi sun haɗa da nau'ikan masu zuwa:

• Rasarancin ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa. Wannan nau'in ƙashi da ƙashi na guringuntsi galibi yana shafar samari kuma yana faruwa a kai da wuya.

• Oswararriyar ƙwararraji. Irin wannan ciwan kashi da guringuntsi yana da matukar wuya a yara da matasa. Zai yuwu ya dawo bayan jiyya kuma yana iya yaduwa zuwa huhu.

Fibrous (connective) nama marurai

Fibrous (connective) ƙwayoyin nama sun haɗa da nau'ikan masu zuwa:

• -Fromromatosis-nau'in lalacewa (wanda kuma ake kira tumoridom ko kuma fibromatosis mai ƙarfi). Wannan ƙwayar ƙwayar fibrous ƙananan ƙira ne (mai yuwuwa ne a hankali). Zai iya dawowa cikin kyallen takarda kusa amma yawanci baya yaduwa zuwa sassan jiki masu nisa. Wasu lokuta fibromatosis-type desmoid na iya dakatar da girma na dogon lokaci. Ba da daɗewa ba, ƙari zai iya ɓacewa ba tare da magani ba.

Ciwan mara daɗi wani lokaci yakan faru ga yara tare da canje-canje a cikin kwayar halittar APC. Canje-canje a cikin wannan kwayar na iya haifar da adenomatous polyposis na iyali (FAP). FAP yanayi ne na gado (wanda aka gada daga iyaye zuwa zuriya) wanda yawancin polyps (ci gaba akan membranes) ke samuwa akan ganuwar cikin hanji da dubura. Shawarwarin kwayoyin halitta (tattaunawa tare da ƙwararren masani game da cututtukan da aka gada da zaɓuɓɓuka don gwajin kwayar halitta) na iya buƙata.

• Dermatofibrosarcoma protuberans. Wannan ƙari ne mai zurfin zurfin fata wanda mafi yawanci yakan samu a cikin akwati, makamai, ko ƙafa. Kwayoyin wannan kumburin suna da wani canjin halittar da ake kira translocation (wani ɓangare na kwayar COL1A1 tana sauya wurare tare da wani ɓangare na kwayar PDGFRB). Don bincika protuberans na dermatofibrosarcoma, ana bincika ƙwayoyin tumo don wannan canjin halittar. Dermatofibrosarcoma protuberans yawanci baya yaduwa zuwa mahaifa ko wasu sassan jiki.

• Ciwon ƙwayar cuta na ƙwayar cuta. Wannan ciwon daji ya ƙunshi ƙwayoyin tsoka, ƙwayoyin halitta masu haɗuwa, da wasu ƙwayoyin ƙwayoyin cuta. Yana faruwa a cikin yara da matasa. Mafi yawan lokuta yakan zama tsari a cikin taushi, huhu, saifa, da mama. Sau da yawa yakan dawo bayan jiyya amma ba safai yake yadawa zuwa sassan jiki ba. An sami wani canjin halittar cikin kusan rabin waɗannan kumburin.

Fibrosarcoma.

Akwai fibrosarcoma iri biyu a cikin yara da matasa:

• Fibrosarcoma na jarirai (wanda ake kira congenital fibrosarcoma). Wannan nau'in fibrosarcoma yawanci yakan faru ne a cikin yara yan shekara 1 zuwa ƙarami kuma ana iya gani a cikin gwajin duban dan tayi. Wannan ƙari yana saurin girma kuma galibi yana da girma a ganewar asali. Yana da wuya ya yadu zuwa sassan jiki masu nisa. Kwayoyin wannan kumburin yawanci suna da wani canjin halitta da ake kira translocation (wani sashi na chromosome daya yana sauya wurare tare da wani sashin chromosome). Don bincika fibrosarcoma na jarirai, ana bincika ƙwayoyin ƙari don wannan canjin halittar. An taɓa ganin irin wannan ƙari a cikin yara ƙanana, amma ba shi da canjin wurin sau da yawa wanda akan gani yara ƙanana.

• Fibrosarcoma na yara. Wannan shine nau'in fibrosarcoma iri daya da aka samo a cikin manya. Kwayoyin wannan kumburin ba su da canjin halittar da aka samo a cikin ƙananan yara fibrosarcoma. (Dubi taƙaitaccen bayanin game da Kulawar Sarcoma mai Girma na Adult don ƙarin bayani.)

• Myxofibrosarcoma. Wannan ƙananan ƙwayar fibrous ne wanda ke faruwa sau da yawa a cikin yara fiye da na manya.

• -Ananan-fibromyxoid sarcoma. Wannan ƙari mai saurin tashi wanda ke zurfafawa a cikin hannaye ko ƙafafu kuma mafi yawa yana shafar matasa da manya. Ciwon zai iya dawowa shekaru da yawa bayan jiyya kuma ya bazu zuwa huhu da rufin bangon kirji. Ana buƙatar bin rayuwa har abada.

• Sclerosing epithelioid fibrosarcoma. Wannan ƙananan ƙwayar fibrous ne wanda ke girma da sauri. Zai iya dawowa ya bazu zuwa wasu sassan jiki shekaru bayan jiyya. Ana buƙatar bin dogon lokaci.

Ciwan jijiyoyin tsoka

Muscleushin ƙashi yana haɗe da ƙashi kuma yana taimakawa jiki motsawa.

• Rhabdomyosarcoma. Rhabdomyosarcoma shine mafi yawan sanyin sarcoma na yara mai laushi yara cikin shekaru 14 da ƙananan. (Dubi taƙaitaccen game da Kula da Rhabdomyosarcoma Yara don ƙarin bayani.)

Muscleananan ƙwayoyin tsoka

Layi mai tsoka mai laushi a cikin jijiyoyin jini da gabobin ciki kamar ciki, hanji, mafitsara, da mahaifa.

• Leiomyosarcoma. An danganta wannan ƙwayar tsoka mai santsi tare da kwayar cutar Epstein-Barr a cikin yara waɗanda suma ke da HIV ko AIDS. Leiomyosarcoma na iya zama wata cuta ta biyu a cikin waɗanda suka tsira daga cutar retinoblastoma, wani lokacin shekaru da yawa bayan fara jiyya na retinoblastoma.

Abinda ake kira fibrohistiocytic marurai

• Plexiform fibrohistiocytic ƙari. Wannan ƙari ne wanda ba kasafai ke faruwa ba wanda ke yawan shafar yara da matasa. Ciwan yakan fara ne azaman ciwan mara zafi a kan ko ƙasan fata a hannu, hannu, ko wuyan hannu. Yana da ƙyar ya bazu zuwa ƙwayoyin lymph da ke kusa ko zuwa huhu.

Jijiyoyin jijiyoyin jikin mutum

Sashin jijiyar ya kunshi yadudduka masu kariya na myelin wanda ke rufe ƙwayoyin jijiyoyin da ba ɓangare na ƙwaƙwalwa ko ƙashin baya ba. Ciwan jijiyoyin jijiyoyin jikin mutum sun hada da nau'ikan masu zuwa:

• Muguwar jijiya jijiyoyin jikin mutum. Wasu yara waɗanda ke da mummunan cututtukan jijiyoyin jijiyoyin jikin mutum suna da mawuyacin yanayin kwayar halitta da ake kira nau'in neurofibromatosis type 1 (NF1). Wannan ƙari na iya zama ƙananan daraja ko babban daraja.

• Cutar Triton mara kyau . Waɗannan ƙananan ciwace-ciwace masu saurin saurin girma wanda ke faruwa galibi a cikin yara masu NF1.

• Ciwon ciki. Wannan ƙari ne mai saurin girma wanda ke faruwa musamman ga yara. Ectomesenchymomas na iya zama a cikin jijiyar ido, ciki, hannu, ko ƙafa.

Pericytic (Perivascular) ƙari

Ciwon daji na Pericytic ya kasance a cikin ƙwayoyin da ke zagaye da jijiyoyin jini. Ciwon daji na Pericytic ya haɗa da nau'ikan masu zuwa:

• Ciwon ciki. Inmantile hemangiopericytoma wani nau'in ƙwayar cuta ce. Yaran da ba su kai shekara 1 ba a lokacin da cutar ta yi kyau na iya samun kyakkyawan hangen nesa. A cikin majinyatan da suka girmi shekara 1, ƙwayar cutar hemangiopericytoma na iya yaduwa zuwa wasu sassan jiki, gami da ƙwayoyin lymph da huhu.

• Myofibromatosis na yara. Myofibromatosis na yara shine wani nau'in myopericytoma. Cutar ƙwayar cuta ce wacce ake samunta sau da yawa a cikin shekaru 2 na farko na rayuwa. Wataƙila akwai nodule ɗaya a ƙarƙashin fata, yawanci a yankin kai da wuya (myofibroma), ko nodules da yawa a cikin fata, tsoka, ko ƙashi (myofibromatosis). A cikin marasa lafiya da ke fama da cutar sankara, cutar kansa ma na iya yaɗuwa zuwa gaɓoɓi. Wadannan ciwace-ciwacen na iya wucewa ba tare da magani ba.

Umumurji waɗanda ba a san asalinsu ba

Umuƙuka waɗanda ba a san asalinsu ba (ba a san irin kwayar cutar ciwon dajin da aka fara yi ba) sun haɗa da nau'ikan masu zuwa:

• Synovial sarcoma. Synovial sarcoma ita ce nau'in nau'in sarcoma mai laushi a cikin yara da matasa. Yawancin lokaci yakan zama cikin kyallen takarda a kewayen haɗin gwiwa a hannu ko ƙafa, amma kuma yana iya zama a cikin akwati, kai, ko wuya. Kwayoyin wannan kumburin yawanci suna da wani canjin halittar da ake kira translocation (wani sashi na chromosome daya yana sauya wurare tare da wani sashin chromosome). Manyan kumburi suna da haɗarin yaduwa zuwa wasu sassan jiki, gami da huhu. Yaran da basu kai shekaru 10 ba wanda kumburinsu yakai santimita 5 ko mafi ƙanƙanta kuma ya samu a hannu ko ƙafafu yana da kyakkyawan hangen nesa.

• Epithelioid sarcoma. Wannan sarcoma ne wanda ba kasafai yake saurin farawa a cikin nama mai taushi kamar mai saurin girma, mai kumburi ba kuma yana iya yaduwa zuwa sassan lymph. Idan ciwon daji ya samu a cikin hannu, ƙafa, ko gindi, za a iya yin biopsy na ƙoshin lafiya don bincika kansar a cikin ƙwayoyin lymph.

• Alveolar mai taushi sarcoma. Wannan ƙananan ƙwayar cuta ne na nama mai taushi wanda ke haɗuwa da kewaya gabobin da sauran kyallen takarda. Yawancin lokaci yakan zama sifa a cikin hannu da ƙafafu amma yana iya faruwa a cikin kyallen takarda na baki, muƙamuƙi, da fuska. Zai iya girma a hankali kuma sau da yawa yana yaduwa zuwa wasu sassan jiki. Sashin sarcoma mai laushi na Alveolar na iya samun kyakkyawan hangen nesa lokacin da ciwon yakai santimita 5 ko ƙarami ko kuma lokacin da aka cire kumburin ta hanyar tiyata. Kwayoyin wannan kumburin yawanci suna da wani canjin kwayar halitta da ake kira translocation (wani ɓangare na kwayar halittar ASSPL tana sauya wurare tare da ɓangaren jigon TFE3). Don bincika sarcoma mai laushi mai alveolar, ana bincika ƙwayoyin tumo don wannan canjin halittar.

• Bayyanan sarcoma na nama mai laushi. Wannan ƙari mai laushi mai saurin tashi wanda ke farawa a cikin jijiya (mai tauri, mai laushi, mai kama da igiya wanda ke haɗa tsoka zuwa ƙashi ko zuwa wani ɓangaren jiki). Bayyanannen ƙwayar sarcoma mafi yawanci yana faruwa a cikin zurfin ƙwayar ƙafa, diddige, da idon kafa. Yana iya yaɗuwa zuwa ƙwayoyin lymph na kusa. Kwayoyin wannan kumburin yawanci suna da wani canjin kwayar halitta da ake kira translocation (wani ɓangare na kwayar EWSR1 tana sauya wurare tare da wani ɓangare na kwayar ATF1 ko CREB1). Don bincika sarcoma mai tsabta na nama mai laushi, ana bincika ƙwayoyin ƙari don wannan canjin halittar.

• Extraskeletal myxoid chondrosarcoma. Wannan nau'in sarcoma mai laushi na iya faruwa a cikin yara da matasa. Yawancin lokaci, yakan zama yaɗuwa zuwa sauran sassan jiki, gami da ƙwayoyin lymph da huhu. Ciwon yana iya dawowa shekaru da yawa bayan jiyya.

• Carin sarcoma Ewing. Duba taƙaitaccen akan Ewing Sarcoma Jiyya don bayani.

• Moananan ƙwayar ƙwayar ƙwayar ƙwayar cuta. Wannan ciwon shine mafi yawan lokuta yake faruwa a cikin rami a cikin ciki, ƙashin ƙugu, da / ko cikin rami a cikin maƙarƙashiya, amma yana iya zama a cikin koda ko wasu gabobin jiki. Zensananan ƙananan ƙwayoyin cuta na iya faruwa a cikin rami. Tumananan ƙwayar ƙwayar ƙwayar ƙwayar cuta za ta iya yaduwa zuwa huhu da sauran sassan jiki. Kwayoyin wannan kumburin yawanci suna da wani canjin halitta da ake kira translocation (wani sashi na chromosome daya yana sauya wurare tare da wani sashin chromosome). Don bincika ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta, ana bincika ƙwayoyin ƙwayoyin don wannan canjin halittar.

• -Arin-renal (extracranial) ƙari na rhabdoid Wannan kumburi mai saurin girma yana samuwa a cikin kyallen takarda mai laushi kamar hanta da mafitsara. Yana yawanci faruwa ga yara ƙanana, gami da jarirai, amma yana iya faruwa a cikin yara da manya. Rhabdoid ciwace-ciwacen ƙwayar cuta na iya haɗuwa da canji a cikin kwayar cutar maye gurbi da ake kira SMARCB1. Irin wannan kwayar halitta tana samar da furotin wanda ke taimakawa sarrafa kwayar halitta. Canje-canje a cikin kwayar halittar SMARCB1 ana iya gado. Shawarwarin kwayoyin halitta (tattaunawa tare da ƙwararren ƙwararren masani game da cututtukan da aka gada da yiwuwar yiwuwar gwajin kwayar halitta) na iya buƙata.

• Perivascular epithelioid cell ƙari (PEComas). Benign PEComas na iya faruwa a cikin yara tare da yanayin gado wanda ake kira tuberous sclerosis. Suna faruwa ne a cikin ciki, hanji, huhu, da kuma gabobin jiki. PEComas suna girma a hankali kuma yawancinsu bazai yuwu ba.

• Ba a rarrabe / sarcoma ba a rarrabe ba. Wadannan cututtukan suna faruwa ne a cikin kasusuwa ko tsokoki wadanda suke hade da kasusuwa kuma suke taimakawa jiki motsawa.

• Bambancin plecorphic sarcoma / mummunan fibros histiocytoma (babban-aji). Wannan nau'in ƙwayar nama mai laushi na iya samuwa a cikin sassan jiki inda marasa lafiya suka karɓi maganin radiation a baya, ko kuma a matsayin cutar kansa ta biyu a cikin yara masu cutar retinoblastoma. Ciwan yana yawan zama a cikin hannu ko ƙafafu kuma yana iya yaɗuwa zuwa wasu sassan jiki. (Dubi taƙaitaccen akan Osteosarcoma da Malignant Fibrous Histiocytoma na Kashi don ƙarin bayani game da mummunan tarihin fibrosus na ƙashi.)

Ciwan jijiyoyin jini

Ciwan jijiyoyin jini sun haɗa da nau'ikan masu zuwa:

• Epithelioid hemangioendothelioma. Epithelioid hemangioendotheliomas na iya faruwa a cikin yara amma sunfi yawa ga manya tsakanin shekaru 30 zuwa 50. Yawanci suna faruwa ne a cikin hanta, huhu, ko ƙashi. Suna iya kasancewa ko dai saurin girma ko kuma jinkirin girma. A kusan kashi ɗaya cikin uku na cututtukan, ƙwayar tana yaduwa zuwa wasu sassan jiki da sauri. (Dubi taƙaitaccen game da Jiyya game da Ciwan umanƙara na Yara don ƙarin bayani.)

• Angiosarcoma na nama mai laushi. Angiosarcoma na nama mai laushi shine ƙari mai saurin girma wanda ke samuwa a cikin jijiyoyin jini ko tasoshin lymph a kowane ɓangare na jiki. Yawancin angiosarcomas suna cikin ko kawai a ƙarƙashin fata. Waɗanda ke cikin ƙaramin taushi mai laushi na iya samarwa a cikin hanta, saifa, ko huhu. Ba kasafai ake samun su ba a cikin yara, waɗanda wani lokacin suna da ƙari fiye da ɗaya a cikin fata ko hanta. Ba da daɗewa ba, hemangioma na yara zai iya zama angiosarcoma na nama mai laushi. (Dubi taƙaitaccen game da Jiyya game da Ciwan umanƙara na Yara don ƙarin bayani.)

Duba taƙaitattun masu zuwa don bayani game da nau'in sarcoma mai laushi wanda ba a haɗa shi cikin wannan taƙaitaccen bayani ba:

• Kula da Yara Rhabdomyosarcoma

• Jiyya na Sarcoma

• Osteosarcoma da mummunan Fibrous Histiocytoma na Kula da Kashi

• Cancers na Musamman na Kula da Yara (ciwan ciwan ciki na ciki)

Wasu dalilai suna tasiri hangen nesa (damar dawowa) da zaɓuɓɓukan magani.

Halin hangen nesa (damar dawowa) da zaɓuɓɓukan magani sun dogara da masu zuwa:

• Bangaren jiki inda kumburin ya fara samuwa.

• Girman da sa na ƙari.

• Nau'in sarcoma mai laushi.

• Yaya zurfin ciwon ƙari a ƙarƙashin fata.

• Ko kumburin ya yadu zuwa wasu wurare a jiki da kuma inda ya yadu.

• Yawan kumburin da ya rage bayan tiyata don cire shi.

• Ko anyi amfani da maganin radiation don magance kumburin.

• Ko dai an gano cutar kansa ko kuma ta sake dawowa (dawo).

Matakai na Softanƙara mai taushi Sarcoma

MAGANAN MAGANA

• Bayan an gano sarcoma mai taushi na yara, ana yin gwaje-gwaje don gano ko kwayoyin cutar kansa sun bazu zuwa wasu sassan jiki.

• Akwai hanyoyi uku da kansar ke yaduwa a jiki.

• Ciwon daji na iya yaduwa daga inda ya fara zuwa sauran sassan jiki.

Bayan an gano sarcoma mai taushi na yara, ana yin gwaje-gwaje don gano ko kwayoyin cutar kansa sun bazu zuwa wasu sassan jiki.

Hanyar da ake amfani da ita don gano ko cutar kansa ta bazu a cikin laushin nama ko zuwa wasu sassan jiki ana kiranta staging. Babu daidaitaccen tsarin tsarkewa don sarcoma nama mai taushi.

Don tsara magani, yana da mahimmanci a san nau'in sarcoma mai laushi, ko za a iya cire ƙwayar ta hanyar tiyata, kuma ko ciwon daji ya bazu zuwa wasu sassan jiki.

Ana iya amfani da waɗannan hanyoyin don gano ko cutar kansa ta bazu:

• Sentinel lymph node biopsy: Cire shingen lymph kumburi a lokacin tiyata. Lymph node na sentinel shine farkon kumburin lymph a cikin rukuni na ƙwayoyin lymph don karɓar magudanan ruwa daga ƙwayar farko. Shine kumburin lymph na farko da mai cutar kansa zai iya yaduwa daga farkon ƙari. Ana yin allurar radiyo da / ko shuɗi mai launi kusa da ƙari. Abun ko fenti yana gudana ta cikin bututun lymph zuwa ƙwayoyin lymph. An cire kumburin lymph na farko don karɓar abu ko fenti. Kwararren likitan kwalliya yana kallon naman a ƙarƙashin madubin likita don neman ƙwayoyin kansa. Idan ba a sami ƙwayoyin kansa ba, ba lallai ba ne a cire ƙarin ƙwayoyin lymph. Wani lokaci, ana samun kumburin lymph kumburi a cikin fiye da rukuni ɗaya. Ana amfani da wannan aikin don epithelioid da sararin ƙwayar sarcoma.

• CT scan (CAT scan): Hanya ce da ke yin jerin hotuna dalla-dalla na wurare a cikin jiki, kamar kirji, wanda aka ɗauka daga kusurwa daban-daban. Ana yin hotunan ne ta wata kwamfuta da aka haɗa ta da na'urar da ke ɗauke da x-ray. Ana iya yin allurar fenti a cikin jijiya ko haɗiye don taimakawa gabobin ko kyallen takarda su fito fili karara. Wannan hanyar ana kiranta kuma aikin sarrafa hoto, tsarin kimiyyar kwamfuta, ko kuma gwada ilimin kimiyyar kwamfuta.

• PET scan: Sanarwar PET hanya ce don nemo ƙwayoyin cuta masu illa a jiki. An sanya ƙwayar glucose mai ƙarancin rediyo (sukari) a cikin jijiya. Na'urar daukar hoton PET tana juyawa a jiki kuma tana yin hoto inda ake amfani da glucose a jiki. Kwayoyin cuta masu illa suna nuna haske a hoton saboda suna aiki kuma suna ɗaukar glucose fiye da ƙwayoyin al'ada. Wannan aikin ana kiran shi scan positron emmo tomography (PET).

• PET-CT scan: Hanya ce wacce ta haɗu da hotuna daga hoton PET da kuma hoton ƙirar hoto (CT). Ana yin sikanin PET da CT a lokaci guda a kan inji ɗaya. Hotuna daga sikann biyu an haɗa su don yin cikakken hoto fiye da kowane gwajin da zai yi shi da kansa.

Akwai hanyoyi uku da kansar ke yaduwa a jiki.

Ciwon daji na iya yadawa ta hanyar nama, tsarin lymph, da jini:

• Nama. Ciwon daji yana yaduwa daga inda ya fara ta girma zuwa yankuna na kusa.

• Tsarin Lymph. Ciwon daji yana yaduwa daga inda ya faro ta hanyar shiga cikin ƙwayoyin cuta. Ciwon daji yana bi ta cikin jirgin ruwan lymph zuwa wasu sassan jiki.

• Jini. Ciwon daji yana yaduwa daga inda ya fara ta hanyar shiga cikin jini. Ciwon daji yana bi ta hanyoyin jini zuwa wasu sassan jiki.

Ciwon daji na iya yaduwa daga inda ya fara zuwa sauran sassan jiki.

Lokacin da cutar daji ta bazu zuwa wani sashin jiki, akan kira shi metastasis. Kwayoyin sankara suna ɓata daga inda suka fara (asalin ƙwayar cuta) kuma suna tafiya ta cikin tsarin lymph ko jini.

• Tsarin Lymph. Ciwon daji ya shiga cikin tsarin laminin, ya ratsa ta cikin jiragen ruwan lymph, kuma ya samar da ƙari (metastatic tumo) a wani ɓangaren jiki.

• Jini. Ciwon kansa ya shiga cikin jini, ya bi ta hanyoyin jini, ya samar da ƙari (ƙwayar metastatic) a wani ɓangaren jiki.

Ciwon ƙwayar ƙwayar ƙwayar cuta shine irin ciwon daji kamar asalin farko. Misali, idan sarcoma mai taushi ya bazu zuwa huhu, ƙwayoyin kansa a cikin huhun ƙwayoyin sarcoma ne masu taushi. Cutar ita ce sarcoma mai laushi mai laushi, ba cutar kansa ta huhu ba.

Maimaitawa da Ci gaban Childhoodarancin Softarancin Sarcoma

Maimaita laushin nama mai laushi sarcoma shine ciwon daji wanda ya sake dawowa (ya dawo) bayan an magance shi. Ciwon daji na iya dawowa a wuri ɗaya ko a wasu sassan jiki.

Ci gaba mai laushi nama sarcoma shine ciwon daji wanda bai amsa magani ba.

Bayanin Zaɓin Jiyya

MAGANAN MAGANA

• Akwai nau'ikan magani daban-daban na marasa lafiya tare da sarcoma mai taushi na yara.

• Yaran da ke da laushin nama mai laushi yara yakamata ƙungiyar masu ba da lafiya ta tsara maganin su wanda ƙwararru ne wajen magance cutar kansa a cikin yara.

• Jiyya don ƙwayar sarcoma mai taushi na yara na iya haifar da sakamako masu illa.

• Ana amfani da nau'i bakwai na daidaitaccen magani:

• Tiyata

• Radiation far

• Chemotherapy

• Lura

• Ciwon da aka yi niyya

• Immunotherapy

• Sauran Magungunan Magunguna

• Ana gwada sababbin nau'ikan magani a gwajin asibiti.

• Gene far

• Marasa lafiya na iya son yin tunani game da shiga cikin gwaji na asibiti.

• Marasa lafiya na iya shiga gwajin asibiti kafin, lokacin, ko bayan fara maganin cutar kansa.

• Ana iya buƙatar gwaje-gwaje na gaba.

Akwai nau'ikan magani daban-daban na marasa lafiya tare da sarcoma mai taushi na yara.

Akwai nau'ikan jiyya iri-iri ga marasa lafiya tare da sarcoma mai taushi na yara. Wasu jiyya suna daidaito (magani da ake amfani dashi yanzu), kuma wasu ana gwada su a gwajin asibiti. Gwajin gwajin magani shine binciken bincike wanda aka tsara don taimakawa inganta ingantattun jiyya na yanzu ko samun bayanai game da sababbin jiyya ga marasa lafiya da ciwon daji. Lokacin da gwaji na asibiti ya nuna cewa sabon magani ya fi magani na yau da kullun, sabon magani na iya zama daidaitaccen magani.

Saboda cutar kansa a cikin yara ba safai ba, ya kamata a yi la'akari da shiga cikin gwajin asibiti. Wasu gwaji na asibiti ana buɗe su ne kawai ga marasa lafiyar da basu fara magani ba.

Yaran da ke da laushin nama mai laushi yara yakamata ƙungiyar masu ba da lafiya ta tsara maganin su wanda ƙwararru ne wajen magance cutar kansa a cikin yara.

Jiyya za ta kula da likitan ilimin likitan yara, likita wanda ya kware kan kula da yara masu cutar kansa. Masanin ilimin likitan yara yana aiki tare da wasu masu ba da kiwon lafiya waɗanda ƙwararru ne wajen kula da yara da sarcoma mai laushi kuma waɗanda suka ƙware a wasu fannonin magani. Waɗannan na iya haɗawa da likitan likitan yara tare da horo na musamman a cikin cire sarcomas mai laushi. Hakanan ana iya haɗa ƙwararrun masanan masu zuwa:

• Likitan yara.

• Radiation oncologist

• Kwararren likitan yara.

• Kwararren likitan yara.

• Gwanayen gyarawa.

• Masanin ilimin psychologist.

• Ma'aikacin zamantakewa.

• Kwararren rayuwar yara.

Jiyya don ƙwayar sarcoma mai taushi na yara na iya haifar da sakamako masu illa.

Don bayani game da illolin da ke farawa yayin magani don cutar kansa, duba shafin Gurbinmu.

Hanyoyi masu illa daga maganin ciwon daji wanda zai fara bayan jiyya kuma ya ci gaba tsawon watanni ko shekaru ana kiransa sakamako na ƙarshe. Sakamakon sakamako na maganin kansa na iya haɗawa da:

• Matsalolin jiki.

• Canje-canje a cikin yanayi, ji, tunani, ilmantarwa, ko ƙwaƙwalwar ajiya.

• Cancer na biyu (sababbin nau'ikan cutar kansa).

Wasu maganganun ƙarshen ana iya magance su ko sarrafa su. Yana da mahimmanci a yi magana da likitocin ɗanka game da illar da cutar kansa za ta iya yi wa ɗanka. (Dubi taƙaitaccen bayanin akan ƙarshen tasirin Jiyya don Ciwon Childhoodan yara don ƙarin bayani.)

Ana amfani da nau'i bakwai na daidaitaccen magani:

Tiyata

Yin aikin tiyata don cire sarcoma mai taushi gaba ɗaya ana yin sa idan zai yiwu. Idan kumburin yana da girma sosai, ana iya ba da magani ta hanyar fitila ko kuma ilimin sankarar magani da farko, don sa girman ya zama karami kuma a rage adadin nama da ake bukatar cirewa yayin aikin. Ana kiran wannan aikin neoadjuvant (preoperative).

Za'a iya amfani da nau'ikan tiyata masu zuwa:

• Wide yanki na gari: Cire ƙwayar kumburi tare da wasu kayan al'ada kusa da shi.

• Yankewa: Tiyata don cire duka ko ɓangaren hannu ko ƙafa tare da cutar kansa.

• Lymphadenectomy: Cire ƙwayoyin lymph tare da ciwon daji.

• Tiyatar Mohs: Tsarin tiyata ne da ake amfani da shi don magance ciwon daji a cikin fata. Ana cire sassan jikin mutum na kayan cutar kansa kuma a sanya su a karkashin wani madubin likita daya bayan daya har sai an cire dukkan nau'ikan cutar kansa. Wannan nau'in tiyatar ana amfani dashi don magance dermatofibrosarcoma protuberans.

An kuma kira shi Mohs micrographic surgery.

• Hepatectomy: Tiyata don cire duka ko ɓangaren hanta.

Ana iya buƙatar tiyata ta biyu don:

• Cire sauran ƙwayoyin cutar kansa.

• Bincika yankin da aka cire kumburin don ƙwayoyin kansa sannan cire ƙarin nama idan an buƙata.

Idan ciwon daji yana cikin hanta, ana iya yin aikin hanta da dasa hanta (an cire hantar kuma a maye gurbinta da mai lafiya daga mai bayarwa).

Bayan likita ya cire dukkan cutar daji da za a iya gani a lokacin tiyatar, wasu marasa lafiya za a iya ba su maganin ƙwaƙwalwar ko kuma maganin furewa bayan tiyata don kashe duk ƙwayoyin cutar kansa da suka rage. Maganin da ake bayarwa bayan tiyatar, don rage haɗarin kamuwa da cutar kansa zai dawo, ana kiran sa adjuvant therapy.

Radiation far

Radiation therapy magani ne na cutar kansa wanda yake amfani da hasken rana mai ƙarfi ko wasu nau'ikan radiation don kashe ƙwayoyin kansa ko hana su girma. Akwai nau'o'in maganin radiation guda biyu:

• Magungunan radiation na waje yana amfani da inji a waje don aika radiation zuwa ga cutar kansa. Wasu hanyoyi na ba da maganin fitila na iya taimakawa kiyaye radiation daga lalata lafiyar nama mai kusa. Wannan nau'ikan maganin radiation na iya haɗa da mai zuwa:

• Magungunan radiation na jiki na Stereotactic: Raunin raunin jikin mutum shine nau'in maganin radiation na waje. Ana amfani da kayan aiki na musamman don sanya mai haƙuri a wuri ɗaya don kowane maganin radiation. Sau ɗaya a rana don kwanaki da yawa, injin radiation yana nufin ya fi girma fiye da yadda ake amfani da radiation kai tsaye a ƙari. Ta hanyar sanya mai haƙuri a cikin matsayi ɗaya don kowane magani, akwai ƙaramin lalacewa ga nama mai lafiya kusa. Wannan hanyar ana kiranta kwayar cututtukan steraotactic na waje-katako na radiation da kuma kula da hasken stereotaxic.

• Magungunan radiation na ciki yana amfani da abu mai tasirin rediyo wanda aka rufe a cikin allurai, tsaba, wayoyi, ko catheters waɗanda aka sanya kai tsaye zuwa ko kusa da ciwon daji.

Ko ana ba da maganin fitilar kafin ko bayan tiyata don cire kansar ya dogara da nau'i da matakin kansar da ake kula da shi, idan duk ƙwayoyin kansa suna ci gaba bayan tiyata, da kuma illolin da ake sa ran jiyya. Ana amfani da farfadowa na waje da na ciki don magance sarcoma mai taushi na yara.

Chemotherapy

Chemotherapy magani ne na cutar kansa wanda ke amfani da magunguna don dakatar da haɓakar ƙwayoyin kansa, ko dai ta hanyar kashe ƙwayoyin ko ta hana su rarraba. Lokacin da ake shan chemotherapy ta baki ko allura a cikin jijiya ko tsoka, magungunan suna shiga cikin jini kuma zasu iya kaiwa ga kwayoyin cutar kansa a cikin jiki duka (systemotherapy chemotherapy). Lokacin da aka sanya chemotherapy kai tsaye zuwa cikin ruwa mai ruɓaɓɓen ciki, gaɓoɓi, ko rami na jiki kamar ciki, magungunan yawanci suna shafar ƙwayoyin kansa ne a waɗancan yankuna. Haɗaɗɗiyar ƙwayar cuta ita ce amfani da fiye da ɗaya maganin ƙwayar cuta.

Hanyar da ake ba da cutar sankara ta dogara da nau'in sarcoma mai laushi da ake kulawa da shi. Yawancin nau'ikan sarcoma mai laushi ba sa amsa magani tare da chemotherapy.

Duba Magungunan da Aka Amince da Sarcoma mai laushi don ƙarin bayani.

Lura

Lura yana lura da yanayin mai haƙuri ba tare da ba da magani ba har sai alamu ko alamu sun bayyana ko canzawa. Ana iya yin duba lokacin da:

• Cikakken cire ƙwayar cutar ba zai yiwu ba.

• Babu sauran magunguna.

• Cutar ƙari ba zai iya lalata kowane gabobi masu mahimmanci ba.

Ana iya amfani da lura don magance fibromatosis-nau'in lalacewa, fibrosarcoma na yara, PEComa, ko epithelioid hemangioendothelioma.

Ciwon da aka yi niyya

Targeted therapy wani nau'in magani ne wanda yake amfani da magunguna ko wasu abubuwa don afkawa ƙwayoyin kansar. Therapwararrun hanyoyin kwantar da hankali yawanci suna haifar da ƙasa da cutar ga ƙwayoyin halitta fiye da cutar sankara ko radiation.

• Masu hana Kinase suna toshe enzyme da ake kira kinase (wani nau'in furotin). Akwai nau'ikan nau'ikan motsa jiki a cikin jiki waɗanda suke da ayyuka daban-daban.

• Masu hana ALK na iya dakatar da cutar kansa daga girma da yadawa. Ana iya amfani da Crizotinib don magance kumburin myofibroblastic mai kumburi da fibrosarcoma na jarirai.

• Tyrosine kinase hanawa (TKIs) toshe sigina da ake buƙata don ciwace-ciwacen girma. Ana amfani da Imatinib don magance cututtukan fata na dermatofibrosarcoma. Ana iya amfani da Pazopanib don magance fibromatosis-type desmoid, epithelioid hemangioendothelioma, da wasu nau'o'in maimaitawa da ci gaba mai laushi sarcoma. Za a iya amfani da Sorafenib don magance fibromatosis irin na lalacewa da epithelioid hemangioendothelioma. Ana iya amfani da Sunitinib don magance sashin sarcoma mai laushi. Ana amfani da Larotrectinib don kula da yara fibrosarcoma. Ana amfani da Ceritinib don magance kumburin myofibroblastic mai kumburi.

• mTOR masu hanawa wani nau'in magani ne da ake niyya wanda yake dakatar da furotin da ke taimakawa ƙwayoyin halitta su rarrabu. Ana amfani da masu hana mTOR don magance ƙananan ƙwayoyin ƙwayoyin ƙwayoyin cuta, PEComas, da epithelioid hemangioendothelioma kuma ana nazarin su don magance cututtukan jijiyoyin jijiyoyin jikin mutum. Sirolimus da temsirolimus sune nau'ikan maganin hana ɗaukar hoto na mTOR.

Sabbin nau'ikan masu hana cin hanci na tyrosine kinase ana nazarin su kamar:

• Entrectinib don yara fibrosarcoma.

• Trametinib don maganin hemangioendothelioma.

Sauran nau'o'in maganin da aka yi niyya ana nazarin su a cikin gwajin asibiti, gami da waɗannan masu zuwa:

• Magungunan Angiogenesis sune nau'in maganin warkewa wanda ke hana ci gaban sababbin jijiyoyin jini da ake buƙata don ciwace-ciwacen girma. Ana nazarin masu hana Angiogenesis, kamar cediranib, sunitinib, da thalidomide don magance sarvema mai laushi alveolar da epithelioid hemangioendothelioma. Ana amfani da Bevacizumab don magance angiosarcoma.

• Masu hanawa na histone methyltransferase (HMT) sune magungunan ƙwayoyi masu niyya waɗanda ke aiki a cikin ƙwayoyin kansa da kuma toshe sigina waɗanda ake buƙata don ciwace-ciwacen su girma. Ana nazarin masu hana HMT, kamar su tazemetostat, don maganin cututtukan jijiyoyin jijiyoyin jikin mutum, epithelioid sarcoma, extraskeletal myxoid chondrosarcoma, da ƙari (extracranial) rhabdoid ƙari.

• Masu hana furotin masu zafi-toshe wasu furotin da ke kare ƙwayoyin tumo da taimaka musu girma. Ganetespib shine mai hana haɓakar furotin mai saurin zafi wanda ake nazari dashi tare da sirolimus mai hana mTOR don ƙananan cututtukan jijiyoyin jijiyoyin jikin mutum wanda ba za'a iya cire shi ta hanyar tiyata ba.

• GASKIYA masu hanawa hanya sune nau'in maganin da aka yi niyya wanda ke aiki a cikin ƙwayoyin cutar kansa kuma yana hana sigina da ake buƙata don ciwace-ciwacen girma.

Ana nazarin masu hana fitattun hanyoyi don maganin cututtukan fibromatosis.

Duba Magungunan da Aka Amince da Sarcoma mai laushi don ƙarin bayani.

Immunotherapy

Immunotherapy magani ne wanda ke amfani da garkuwar jikin mara lafiya don yaƙar kansa. Abubuwan da jiki ya yi ko aka yi a dakin gwaje-gwaje ana amfani da su don haɓaka, kai tsaye, ko maido da kariya ta jiki daga cutar kansa. Wannan nau'in magani ana kiransa biotherapy ko ilimin ilimin halittu.

Interferon da magungunan rigakafi na rigakafi sune nau'ikan immunotherapy.

• Interferon yana tsangwama tare da rarrabuwar ƙwayoyin ƙwayoyin cuta kuma yana iya rage ci gaban ƙari. Ana amfani dashi don magance epithelioid hemangioendothelioma.

• Maganin hana shiga ciki na kariya: Wasu nau'ikan kwayoyin rigakafi, kamar su kwayoyin T, da wasu kwayoyin cutar kansa suna da wasu sunadarai, wadanda ake kira sunadarin shinge, a saman su wanda ke kiyaye amsoshin rigakafin a duba. Lokacin da ƙwayoyin daji ke da yawancin waɗannan sunadaran, ƙwayoyin T ba za su auka musu ba. Masu hana abubuwan hana ruwa kariya suna toshe wadannan sunadaran kuma karfin kwayar T don kashe kwayoyin cutar kansa ya karu.

Akwai nau'ikan maganin hana hana ruwa guda biyu na kariya:

• Mai hana CTLA-4: CTLA-4 furotin ne akan saman ƙwayoyin T wanda ke taimakawa ci gaba da ba da kariya ga jiki. Lokacin da CTLA-4 ke haɗuwa da wani furotin da ake kira B7 akan kwayar cutar kansa, yana dakatar da kwayar T daga kashe kwayar cutar kansa. Masu hana CTLA-4 sun haɗa zuwa CTLA-4 kuma suna ba da ƙwayoyin T damar kashe ƙwayoyin kansa. Ipilimumab wani nau'in mai hana CTLA-4 ne wanda ake nazarin sa don magance angiosarcoma.

Mai hana shigowar shinge Abubuwan bincike, kamar B7-1 / B7-2 akan ƙwayoyin gabatarwa na antigen (APC) da CTLA-4 akan ƙwayoyin T, suna taimakawa kiyaye maganganun garkuwar jiki a cikin bincike. Lokacin da mai karɓar T-cell (TCR) ke ɗaure ga antigen da kuma manyan sunadarai masu rikitarwa na tarihi (MHC) akan APC da CD28 suna ɗaure zuwa B7-1 / B7-2 akan APC, ana iya kunna T cell. Koyaya, ɗaura B7-1 / B7-2 zuwa CTLA-4 yana riƙe da ƙwayoyin T a cikin yanayin aiki saboda haka basu sami ikon kashe ƙwayoyin ƙari a cikin jiki (ɓangaren hagu). Katange ɗaurin B7-1 / B7-2 zuwa CTLA-4 tare da mai hana kariya na kariya (anti-CTLA-4 antibody) yana ba da damar ƙwayoyin T suyi aiki kuma su kashe ƙwayoyin tumo (ɓangaren dama).

• Mai hana PD-1: PD-1 furotin ne akan saman ƙwayoyin T wanda ke taimakawa ci gaba da ba da kariya ga jiki. Lokacin da PD-1 ya haɗu da wani furotin da ake kira PDL-1 akan kwayar sankara, yakan dakatar da kwayar T daga kashe kwayar cutar kansa. Masu hana PD-1 sun haɗa zuwa PDL-1 kuma suna ba da ƙwayoyin T damar kashe ƙwayoyin kansa. Pembrolizumab wani nau'in mai hana PD-1 ne wanda ake amfani dashi don magance ci gaba da maimaituwa da laushi sarcoma nama. Nivolumab wani nau'in mai hana PD-1 ne wanda ake nazarin don magance angiosarcoma.

Mai hana shigowar shinge Binciken sunadarai, kamar PD-L1 akan ƙwayoyin tumo da PD-1 akan ƙwayoyin T, suna taimakawa kiyaye maganganun rigakafi a cikin bincike. Ofaurin PD-L1 zuwa PD-1 yana kiyaye ƙwayoyin T daga kashe ƙwayoyin tumo a jiki (ɓangaren hagu). Katange ɗaurin PD-L1 zuwa PD-1 tare da mai hana kariya na kariya (anti-PD-L1 ko anti-PD-1) yana ba wa ƙwayoyin T damar kashe ƙwayoyin tumor (ɓangaren dama)

Sauran Magungunan Magunguna

Magungunan steroid yana da tasirin antitumor a cikin ƙwayoyin myofibroblastic mai kumburi.

Maganin Hormone magani ne na cutar kansa wanda ke kawar da homonomi ko toshe aikin su kuma ya hana ƙwayoyin cutar kansa girma. Hormones abubuwa ne da gland ke yi a jiki kuma suna yawo a cikin jini. Wasu kwayoyin na iya haifar da wasu cututtukan kansa. Idan gwaje-gwaje sun nuna cewa ƙwayoyin cutar kansa suna da wuraren da homonomi zasu iya haɗawa (masu karɓa), ana amfani da ƙwayoyi, tiyata, ko kuma maganin fuka don rage samar da homon ɗin ko toshe su daga aiki. Antiestrogens (magungunan da ke toshe estrogen), kamar su tamoxifen, ana iya amfani dasu don kula da fibromatosis irin na lalacewa. Ana nazarin Prasterone don maganin sarcoma na synovial.

Magungunan cututtukan cututtukan ƙwayoyin cuta (NSAIDs) magunguna ne (kamar su aspirin, ibuprofen, da naproxen) waɗanda ake amfani da su don rage zazzaɓi, kumburi, zafi, da kuma ja. A cikin maganin cututtukan fibromatosis irin na desmoid, ana iya amfani da NSAID da ake kira sulindac don taimakawa toshe haɓakar ƙwayoyin kansa.

Ana gwada sababbin nau'ikan magani a gwajin asibiti.

Wannan ɓangaren taƙaitaccen bayani yana bayanin jiyya waɗanda ake nazarin su a gwajin asibiti. Yana iya ba ambaci kowane sabon magani ana nazarin. Ana samun bayani game da gwaji na asibiti daga gidan yanar gizon NCI.

Gene far

Ana nazarin ilimin jinsi don sarcoma na synovial na yara wanda ya sake dawowa, yaɗu, ko ba za a iya cire shi ta hanyar tiyata. Wasu daga cikin kwayoyin T na marasa lafiya (wani nau'in farin jini ne) ana cire su kuma ana canza kwayoyin halittar da ke cikin kwayoyin a dakin gwaje-gwaje (injiniyar kwayar halitta) ta yadda za su afkawa takamaiman kwayoyin cutar kansa. Ana ba su baya ga mai haƙuri ta hanyar jiko.

Marasa lafiya na iya son yin tunani game da shiga cikin gwaji na asibiti.

Ga wasu marasa lafiya, shiga cikin gwaji na asibiti na iya zama mafi kyawun zaɓin magani. Gwajin gwaji wani bangare ne na aikin binciken cutar kansa. Ana yin gwaje-gwajen asibiti don gano ko sabbin maganin cutar daji suna da lafiya da tasiri ko kuma sun fi magani na yau da kullun.

Yawancin yau da kullun na yau da kullun don cutar kansa sun dogara ne akan gwajin asibiti na farko. Marasa lafiya da ke cikin gwaji na asibiti na iya karɓar daidaitaccen magani ko kuma su kasance cikin farkon waɗanda za su karɓi sabon magani.

Marasa lafiya da ke shiga cikin gwaji na asibiti suma suna taimakawa inganta hanyar da za a bi da kansar a nan gaba. Koda lokacin gwajin asibiti bai haifar da sababbin magunguna ba, sau da yawa sukan amsa mahimman tambayoyi kuma suna taimakawa ci gaba da bincike gaba.

Marasa lafiya na iya shiga gwajin asibiti kafin, lokacin, ko bayan fara maganin cutar kansa.

Wasu gwaji na asibiti kawai sun haɗa da marasa lafiya waɗanda ba su sami magani ba tukuna. Sauran gwaje-gwajen suna gwada jiyya ga marasa lafiya waɗanda cutar kansa ba ta samu sauki ba. Hakanan akwai gwaji na asibiti da ke gwada sabbin hanyoyin dakatar da cutar kansa daga sake dawowa (dawowa) ko rage tasirin maganin kansar.

Gwajin gwaji na gudana a sassa da yawa na ƙasar. Bayani game da gwajin asibiti wanda NCI ke tallafawa ana iya samun shi akan shafin binciken gwaji na NCI. Ana iya samun gwajin gwaji na asibiti wanda wasu kungiyoyi ke tallafawa akan gidan yanar gizon ClinicalTrials.gov.

Ana iya buƙatar gwaje-gwaje na gaba.

Za a iya maimaita wasu gwaje-gwajen da aka yi don gano cutar kansa ko don gano matakin cutar kansa. Za a maimaita wasu gwaje-gwaje don ganin yadda magani ke aiki. Shawarwari game da ci gaba, canji, ko dakatar da magani na iya dogara ne da sakamakon waɗannan gwaje-gwajen.

Wasu daga cikin gwaje-gwajen za a ci gaba da yi daga lokaci zuwa lokaci bayan an gama jiyya. Sakamakon waɗannan gwaje-gwajen na iya nuna idan yanayin ɗanku ya canza ko kuma idan ciwon daji ya sake dawowa (dawo). Wadannan gwaje-gwajen wasu lokuta ana kiran su gwaje-gwaje na gaba ko dubawa.

Zaɓuɓɓukan Jiyya don Sabon Binciken Softarƙwara na Softarƙancin Sarcoma

A Wannan Sashin

• Fatwaro mai uman kitse

• Liposarcoma

• Kashi da Gangar Jiki

• Rasarancin ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa

• Oswararriyar ƙwararraji

• Fibrous (Haɗuwa) Tumun nama

• Fibromatosis-nau'in ɓarna

• Dermatofibrosarcoma protuberans

• Ciwon ƙwayar cuta na ƙwayar cuta

• Fibrosarcoma

• Myxofibrosarcoma

• -Ananan-fibromyxoid sarcoma

• Sclerosing epithelioid fibrosarcoma

• Umanƙarar tsoka da kwarangwal

• Rhabdomyosarcoma

• Musananan ƙwayoyin cuta

• Leiomyosarcoma

• Abinda ake kira Fibrohistiocytic Tumors

• Plexiform fibrohistiocytic ƙari

• Jijiyoyin jijiyoyin jijiya

• Muguwar jijiya jijiyoyin jikin mutum

• Cutar Triton mara kyau

• Ciwon ciki

• Pericytic (Perivascular) ƙari

• Hannen ciki mai dauke da ciki

• Myofibromatosis na yara

• Umuƙuron Asalin knownarfin Sanarwar (ba a san wurin da ƙari ya fara ba)

• Synovial sarcoma

• Epithelioid sarcoma

• Alveolar mai taushi sarcoma

• Bayyanan sarcoma na nama mai laushi

• Extraskeletal myxoid chondrosarcoma

• Carin sarcoma Ewing

• Moananan ƙwayar ƙwayar ƙwayar ƙwayar cuta

• -Arin-renal (extracranial) ƙari na rhabdoid

• Perivascular epithelioid cell ƙari (PEComas)

• Uncategorized / Unclassified Sarcoma

• Bambancin sarcoma mai banƙyama / mummunan fibio histiocytoma (babban matsayi)

• Vananan Van Ruwa

• Epithelioid hemangioendothelioma

• Angiosarcoma na nama mai laushi

• Tsarin nama na Childhoodananan Matashi na Sarcoma

Don bayani game da jiyya da aka jera a ƙasa, duba sashin Kula da Zaɓin Jiyya

Fatwaro mai uman kitse

Liposarcoma

Jiyya na liposarcoma na iya haɗawa da masu zuwa:

• Tiyata don cire ƙari gaba daya. Idan ba a kawar da cutar kansa gaba ɗaya, za a iya yin tiyata ta biyu.

• Chemotherapy don rage ƙwayar cuta, sannan a yi aikin tiyata.

• Radiation far kafin ko bayan tiyata.

Kashi da Gangar Jiki

Rasarancin ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa

Jiyya na ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta na iya haɗawa da masu zuwa:

• Tiyata don cire ƙari gaba daya. Za a iya ba da aikin kashe hasken rana kafin da / ko bayan tiyata.

• Chemotherapy ya biyo bayan tiyata. Chemotherapy tare da ko ba tare da maganin radiation ana ba shi bayan tiyata.

Oswararriyar ƙwararraji

Jiyya na osteosarcoma mai yaduwa na iya haɗa da masu zuwa:

• Yin aikin tiyata don cire ƙwayar cutar gaba ɗaya, sannan bi da cutar sankara.

Dubi taƙaitaccen akan Osteosarcoma da Malignant Fibrous Histiocytoma na Kashi don ƙarin bayani game da maganin osteosarcoma.

Fibrous (Haɗuwa) Tumun nama

Fibromatosis-nau'in ɓarna

Jiyya na nau'in fibromatosis mai lalacewa na iya haɗa da masu zuwa:

• Tiyata don cire ƙari gaba daya.

• Lura, ga ciwace-ciwacen da ba a cire su gaba ɗaya ta hanyar tiyata ko waɗanda suka sake dawowa (dawowa) kuma da alama ba za su lalata mahimman gabobin jiki ba.

• Chemotherapy ga ciwace-ciwacen da ba a cire su gaba ɗaya ta hanyar tiyata ko waɗanda suka sake dawowa.

• Target ɗin da aka yi niyya (sorafenib ko pazopanib).

• Magungunan rigakafin cututtukan ƙwayoyin cuta (NSAID).

• Magungunan maganin antiestrogen.

• Radiation far.

• Gwajin gwaji na maganin farfadowa tare da maɓallin hanyar NOTCH.

Dermatofibrosarcoma protuberans

Jiyya na dermatofibrosarcoma protuberans na iya haɗa da masu zuwa:

• Yin aikin tiyata don cire ƙwayar cutar gaba ɗaya lokacin da zai yiwu. Wannan na iya haɗawa da aikin Mohs.

• Radiation far kafin ko bayan tiyata.

• Radiation radiation da niyya (imatinib) idan ba za'a iya cire kumburin ko kuma ya dawo ba.

Ciwon ƙwayar cuta na ƙwayar cuta

Jiyya na cututtukan ƙwayoyin cuta na ƙwayoyin cuta na iya haɗawa da masu zuwa:

• Yin aikin tiyata don cire ƙwayar cutar gaba ɗaya lokacin da zai yiwu.

• Chemotherapy.

• Steroid far.

• Magungunan rigakafin cututtukan ƙwayoyin cuta (NSAID).

• Target din da aka yi niyya (crizotinib da ceritinib).

Fibrosarcoma

Fibrosarcoma na yara

Jiyya na yara fibrosarcoma na iya haɗa da masu zuwa:

• Yin tiyata don cire ƙari lokacin da zai yiwu, sannan bin kallo.

• Yin aikin tiyata ya biyo baya ta chemotherapy.

• Chemotherapy don rage ƙwayar cuta, sannan a yi aikin tiyata.

• Target din da aka yi niyya (crizotinib da larotrectinib).

• Gwajin gwaji wanda ke bincikar samfurin ƙwayar cutar mai haƙuri don wasu canje-canje na asali. Nau'in maganin da aka yiwa niyya wanda za'a baiwa mai haƙuri ya dogara da nau'in canjin halittar mutum.

• Gwajin gwaji na maganin farfadowa (larotrectinib ko entrectinib).

Fibrosarcoma na yara

Jiyya na manya-manya fibrosarcoma na iya haɗa da masu zuwa:

• Yin aikin tiyata don cire ƙwayar cutar gaba ɗaya lokacin da zai yiwu.

Myxofibrosarcoma

Jiyya na myxofibrosarcoma na iya haɗa da masu zuwa:

• Tiyata don cire ƙari gaba daya.

-Ananan-fibromyxoid sarcoma

Jiyya na ƙananan-fibromyxoid sarcoma na iya haɗa da masu zuwa:

• Tiyata don cire ƙari gaba daya.

Sclerosing epithelioid fibrosarcoma

Jiyya na sclerosing epithelioid fibrosarcoma na iya haɗa da masu zuwa:

• Tiyata don cire ƙari gaba daya.

Umanƙarar tsoka da kwarangwal

Rhabdomyosarcoma

Dubi taƙaitaccen game da Kula da Rhabdomyosarcoma Yara.

Musananan ƙwayoyin cuta

Leiomyosarcoma

Jiyya na leiomyosarcoma na iya haɗa da masu zuwa:

• Chemotherapy.

Abinda ake kira Fibrohistiocytic Tumors

Plexiform fibrohistiocytic ƙari

Jiyya na cututtukan fibrohistiocytic plexiform na iya haɗa da masu zuwa:

• Tiyata don cire ƙari gaba daya.

Jijiyoyin jijiyoyin jijiya

Muguwar jijiya jijiyoyin jikin mutum

Jiyya na cututtukan jijiyoyin jijiyoyin jijiyoyin jikin mutum na iya haɗawa da masu zuwa:

• Yin aikin tiyata don cire ƙwayar cutar gaba ɗaya lokacin da zai yiwu.

• Radiation far kafin ko bayan tiyata.

• Chemotherapy, don ciwace-ciwacen da ba za a iya cire su ta hanyar tiyata ba.

• Gwajin gwaji wanda ke bincikar samfurin ƙwayar cutar mai haƙuri don wasu canje-canje na asali. Nau'in maganin da aka yiwa niyya wanda za'a baiwa mai haƙuri ya dogara da nau'in canjin halittar mutum.

• Gwajin gwaji na maganin farfadowa (ganetespib ko sirolimus), don ciwace-ciwacen da ba za a iya cire su ta hanyar tiyata ba.

• Gwajin gwaji na maganin warkewa (tazemetostat).

Ba a bayyane yake ba ko ba da magani na radiation ko kuma maganin bayan an gama tiyata yana inganta amsar kumburin maganin.

Cutar Triton mara kyau

Za a iya magance cututtukan Triton mara kyau kamar rhabdomyosarcomas kuma sun hada da tiyata, chemotherapy, ko radiation radiation. Ba a bayyane yake ba ko ba da maganin fuka-fuka ko kuma maganin kimiyyar magani na inganta amsar kumburin maganin.

Ciwon ciki

Jiyya na ectomesenchymoma na iya haɗa da masu zuwa:

• Tiyata.

• Chemotherapy.

• Radiation far.

Pericytic (Perivascular) ƙari

Hannen ciki mai dauke da ciki

Jiyya na jariri hemangiopericytoma na iya haɗawa da masu zuwa:

• Chemotherapy.

Myofibromatosis na yara

Jiyya na ƙananan yara na iya haɗawa da masu zuwa:

Hade chemotherapy.

Umuƙuron Asalin knownarfin Sanarwar (ba a san wurin da ƙari ya fara ba)

Synovial sarcoma

Jiyya na sarcoma na synovial na iya haɗa da masu zuwa:

• Tiyata. Za'a iya ba da aikin kashe hasken rana da / ko kuma ana iya ba shi magani kafin ko bayan tiyata.

• Chemotherapy.

• Magungunan radiation na stereotactic don ƙari wanda ya bazu zuwa huhu.

• Gwajin gwaji na maganin jinsi.

• Gwajin gwaji na maganin hormone.

Epithelioid sarcoma

Jiyya na sarcoma epithelioid na iya haɗa da masu zuwa:

• Yin aikin tiyata don cire ƙari lokacin da zai yiwu.

• Chemotherapy.

• Radiation far kafin ko bayan tiyata.

• Gwajin gwaji na maganin warkewa (tazemetostat).

Alveolar mai taushi sarcoma

Jiyya na sarcoma mai laushi mai laushi zai iya haɗa da masu zuwa:

• Yin aikin tiyata don cire ƙwayar cutar gaba ɗaya lokacin da zai yiwu.

• Radiation far kafin ko bayan tiyata, idan ƙari ba za a iya cire shi gaba daya ta hanyar tiyata.

• Maganin da aka yi niyya (sunitinib).

• Gwajin gwaji na asibiti (cediranib ko sunitinib) don yara.

Bayyanan sarcoma na nama mai laushi

Jiyya na sarcoma mai tsabta na nama mai laushi na iya haɗa da masu zuwa:

• Yin aikin tiyata don cire ƙari lokacin da zai yiwu.

• Radiation far kafin ko bayan tiyata.

Extraskeletal myxoid chondrosarcoma

Jiyya na ƙwayar myxoid chondrosarcoma na iya haɗa da masu zuwa:

• Yin aikin tiyata don cire ƙari lokacin da zai yiwu.

• Radiation far.

• Gwajin gwaji na maganin warkewa (tazemetostat).

Carin sarcoma Ewing

Dubi taƙaitaccen game da Jiyya na Sarcoma.

Moananan ƙwayar ƙwayar ƙwayar ƙwayar cuta

Babu daidaitaccen magani don ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta. Jiyya na iya haɗa da masu zuwa:

• Yin aikin tiyata don cire ƙwayar cutar gaba ɗaya lokacin da zai yiwu.

• Chemotherapy ya biyo bayan tiyata.

• Radiation far.

• Chemotherapy da maganin da aka yi niyya (temsirolimus), don ciwace-ciwacen maimaitawa.

-Arin-renal (extracranial) ƙari na rhabdoid

Jiyya na ƙarin-renal (extracranial) rhabdoid ƙari na iya haɗa da masu zuwa:

• Yin aikin tiyata don cire ƙari lokacin da zai yiwu.

• Chemotherapy.

• Radiation far.

• Gwajin gwaji wanda ke bincikar samfurin ƙwayar cutar mai haƙuri don wasu canje-canje na asali. Nau'in maganin da aka yiwa niyya wanda za'a baiwa mai haƙuri ya dogara da nau'in canjin halittar mutum.

• Gwajin gwaji na maganin warkewa (tazemetostat).

Perivascular epithelioid cell ƙari (PEComas)

Jiyya na cututtukan ƙwayar epithelioid cell na iya haɗawa da masu zuwa:

• Tiyata don cire ƙari.

• Lura da aikin tiyata.

• Maganin da aka yi niyya (sirolimus), don ciwace-ciwacen da ke da wasu canje-canje na kwayar halitta kuma ba za a iya cire su ta hanyar tiyata.

Uncategorized / Unclassified Sarcoma

Bambancin sarcoma mai banƙyama / mummunan fibio histiocytoma (babban matsayi)

Babu daidaitaccen magani ga waɗannan ciwace-ciwacen.

Dubi taƙaitaccen akan Osteosarcoma da Malignant Fibrous Histiocytoma na Kashi na Kashi don bayani game da maganin mummunan tarihin fibros na kashi.

Vananan Van Ruwa

Epithelioid hemangioendothelioma

Jiyya na epithelioid hemangioendothelioma na iya haɗa da masu zuwa:

• Lura.

• Yin aikin tiyata don cire ƙari lokacin da zai yiwu.

• Immunotherapy (interferon) da niyya far (thalidomide, sorafenib, pazopanib, sirolimus) don ciwace-ciwacen da za su iya yaduwa.

• Chemotherapy.

• Total hepatectomy da kuma dashen hanta lokacin da ciwon yake a cikin hanta.

• Gwajin gwaji na maganin warkewa (trametinib).

Angiosarcoma na nama mai laushi

Maganin angiosarcoma na iya haɗawa da masu zuwa:

• Tiyata don cire ƙari gaba daya.

• Haɗuwa da tiyata, jiyyar cutar sankara, da kuma jujjuyawa don angiosarcomas waɗanda suka bazu.

• Maganin da aka yi niyya (bevacizumab) da chemotherapy don angiosarcomas wanda ya fara a matsayin jaririn hemangiomas.

• Gwajin gwaji na ilimin kimiya tare da ko ba tare da niyya ba (pazopanib).

• Gwajin gwaji na maganin rigakafi (nivolumab da ipilimumab).

Tsarin nama na Childhoodananan Matashi na Sarcoma

Jiyya na sarcoma mai laushi na yara wanda ya yada zuwa wasu sassan jiki a ganewar asali na iya haɗa da masu zuwa:

• Chemotherapy da radiation far. Za a iya yin aikin tiyata don cire ƙwayoyin cutar da suka bazu zuwa huhu.

• Magungunan radiation na stereotactic na cututtukan da suka bazu zuwa huhu.

Don maganin wasu nau'o'in ƙwayoyin cuta, duba Zaɓuɓɓukan Jiyya don Softanƙarar Softanƙara mai laushi Sarananan Yara.

Zaɓuɓɓukan Jiyya don Ciwon Siki mai laushi na Childhoodananan yara Sarcoma

Jiyya na maimaitawa ko ci gaba mai laushi yara sarcoma na iya haɗa da masu zuwa:

• Yin aikin tiyata don cire kansar da ta dawo inda ta fara ko kuma ta bazu zuwa huhu.

• Yin aikin tiyata wanda ke biyo baya ta hanyar waje ko na cikin gida, idan ba a riga an ba da magungunan ba.

• Yin aikin tiyata don cire hannu ko ƙafa tare da cutar kansa, idan an riga an ba da magungunan hasara.

• Yin tiyata tare da ko ba tare da chemotherapy don sarcoma na synovial ba.

• Chemotherapy.

• Tsarin da aka yi niyya (pazopanib).

• Immunotherapy (pembrolizumab).

• Magungunan radiation na jikin mutum don cutar kansa wanda ya bazu zuwa sauran sassan jiki, musamman huhu.

• Gwajin gwaji na sabon tsarin sankarar magani tare da ko ba tare da niyya far (pazopanib).

• Gwajin gwaji wanda ke bincikar samfurin ƙwayar cutar mai haƙuri don wasu canje-canje na asali. Nau'in maganin da aka yiwa niyya wanda za'a baiwa mai haƙuri ya dogara da nau'in canjin halittar mutum.

Yi amfani da binciken bincikenmu na asibiti don nemo NCI na goyan bayan gwajin asibiti wanda ke karɓar marasa lafiya. Kuna iya bincika gwaji dangane da nau'in ciwon daji, shekarun mai haƙuri, da kuma inda ake yin gwajin. Ana samun cikakken bayani game da gwaji na asibiti.

Don Moreara Koyo Game da Softarƙashin Softarya na Sarcoma

Don ƙarin bayani daga Cibiyar Cancer ta cerasa game da laushin sarcoma mai laushi na yara, duba mai zuwa:

• Tattakin Naman Sarcoma Home Page

• Tomography Tomography (CT) Scans da Ciwon daji

• An Amince da Magunguna don Sarcoma mai laushi

• Magungunan Ciwon Cutar da Aka Yi niyya

• MyPART - Cibiyar Sadarwar Yara da Yara

Don ƙarin bayani game da cutar sankarar yara da sauran albarkatun kansar gaba ɗaya, duba masu zuwa:

• Game da Ciwon daji

• Ciwon Yara

• Binciken Cure don Ciwon Childrenan yara

• Matsayi na Late na Jiyya don Ciwon Yara

• Matasa da Samari da Ciwon daji

• Yara da Ciwon daji: Jagora ga Iyaye

• Ciwon daji a cikin Yara da Matasa

• Tsayawa

• Yin fama da Ciwon daji

• Tambayoyi don Tambayar Doctor game da Ciwon daji

• Don Tsira da Kulawa