Types/myeloproliferative/patient/myelodysplastic-treatment-pdq

Maganin Ciwon Siki na Myelodysplastic ( –) –Shafin haƙuri

Janar Bayani Game da Ciwon Myelodysplastic Syndromes

MAGANAN MAGANA

• Ciwon mahaɗan Myelodysplastic wani rukuni ne na cutar kansa wanda ƙwayoyin jinin da ba su balaga ba a cikin kashin ƙashi ba su girma ko zama lafiyayyun ƙwayoyin jini.

• An gano nau'o'in cututtukan myelodysplastic daban-daban bisa ga wasu canje-canje a cikin ƙwayoyin jini da ɓarke ​​na ƙashi.

• Shekaru da maganin da suka gabata tare da chemotherapy ko radiation na shafar haɗarin cututtukan myelodysplastic.

• Alamomi da alamomin ciwo na myelodysplastic sun haɗa da ƙarancin numfashi da jin kasala.

• Ana amfani da gwaje-gwajen da ke bincikar jini da ƙashi a gano (gano) da kuma gano cututtukan myelodysplastic.

• Wasu dalilai suna tasiri hangen nesa da zaɓuɓɓukan magani.

Ciwon mahaɗan Myelodysplastic wani rukuni ne na cutar kansa wanda ƙwayoyin jinin da ba su balaga ba a cikin kashin ƙashi ba su girma ko zama lafiyayyun ƙwayoyin jini.

A cikin lafiyayyen mutum, kashin ƙashi yana yin sel na jini (ƙwayoyin da ba su balaga ba) waɗanda suka zama ƙwayoyin jini girma a kan lokaci.

Anatomy na kashi. Kashin ya kunshi karamin kashi, kashin baya, da kashin baya. Karamin kashi yana yin layin waje na ƙashi. Ana samun kashin Spongy galibi a ƙarshen ƙasusuwa kuma yana ɗauke da jajaja. Ana samun kasusuwan kasusuwa a tsakiyar mafi yawan kasusuwa kuma yana da jijiyoyi da yawa. Akwai kashin kashi biyu: ja da rawaya. Jan kashin jini ya ƙunshi ƙwayoyin jini wanda zai iya zama jajayen ƙwayoyin jini, fararen ƙwayoyin jini, ko platelets. An sanya kasusuwan rawaya mafi yawan mai.

Stemwayar ƙwayar ƙwayar jini na iya zama ƙwayar ƙwayar ƙwayar lymphoid ko ƙwayar ƙwayar myeloid. Kwayar kwayar lymphoid ta zama farin jini. Kwayar kara kuzari ta myeloid ta zama ɗayan nau'ikan nau'ikan ƙwayoyin jini uku masu girma:

• Jajayen jini wadanda suke daukar iskar oxygen da sauran abubuwa zuwa dukkan kyallen takarda.

• Platelets wadanda suke samar da daskararren jini dan tsaida zubar jini.

• Farin jini wanda ke yakar kamuwa da cuta.

Ci gaban kwayar jini. Kwayar sel ta jini tana wucewa ta matakai da yawa don zama jajayen jini, platelet, ko kuma farin jini.

A cikin majiyyacin da ke fama da cutar ta myelodysplastic, ƙwayoyin jini na jini (ƙwayoyin da ba su balaga ba) ba sa zama jajayen ƙwayayin jini, farin ƙwayoyin jini, ko platelets a cikin ɓarin kashi. Wadannan kwayoyin jinin da basu balaga ba, wadanda ake kira blasts, basa aiki yadda yakamata kuma ko dai su mutu a cikin kashin kashi ko kuma jim kadan da shiga cikin jini. Wannan yana barin ƙaramin ɗaki ga lafiyayyen ƙwayoyin jini, da jajayen ƙwayoyin jini, da platelets da za su yi a cikin ɓarke. Lokacin da ƙananan ƙwayoyin jini ke da ƙarancin lafiya, kamuwa da cuta, ƙarancin jini, ko kuma saurin zubar jini na iya faruwa.

An gano nau'o'in cututtukan myelodysplastic daban-daban bisa ga wasu canje-canje a cikin ƙwayoyin jini da ɓarke ​​na ƙashi.

• Karancin jini: Karancin jan jini yana da yawa a cikin jini kuma mai haƙuri yana da karancin jini. Adadin fararen ƙwayoyin jini da platelet na al'ada ne.

• Anemia mai banƙyama tare da murfin gefen zobe: Akwai ƙananan ƙwayoyin jini a cikin jini kuma mai haƙuri yana da karancin jini. Kwayoyin jinin ja suna da baƙin ƙarfe da yawa a cikin kwayar. Adadin fararen ƙwayoyin jini da platelet na al'ada ne.

• Karancin jini tare da yawan fashewa: Akwai karancin jan jini a cikin jini kuma mai haƙuri yana da karancin jini. Kashi biyar cikin dari zuwa kashi 19 cikin 100 na ƙwayoyin jikin da ke cikin ɓarin jijiyoyi sune fashewa. Hakanan za'a iya samun canje-canje ga ƙwayoyin jinin farin da platelets. Karancin jini tare da yawan fashewa na iya ci gaba zuwa cutar sankarar myeloid mai tsanani (AML). Dubi Adult Acute Muteloid Leukemia Treatment summary don ƙarin bayani.

• Hanyar cytopenia mai saurin wartsakewa tare da cutar dasplasia ta multilineage: Kadan ne daga aƙalla nau'ikan ƙwayoyin jini guda biyu (jajayen jini, platelets, ko kuma farin ƙwayoyin jini). Kasa da kashi 5 cikin dari na kwayoyin halittar da ke cikin kashin kasusuwa su ne fashewa kuma kasa da 1% na sel din da ke cikin jini fashewa ce. Idan kwayoyin jan jini ya shafa, suna iya samun karin baƙin ƙarfe. Tsarin cytopenia mai banƙyama na iya ci gaba zuwa cutar sankarar myeloid mai tsanani (AML).

• Saurin cytopenia tare da dysplasia na cikin ruwa: Kadan ne daga kwayar jinin guda daya (jajayen jini, platelets, ko kuma farin jini). Akwai canje-canje a cikin 10% ko fiye na wasu nau'ikan ƙwayoyin jini guda biyu. Kasa da kashi 5 cikin dari na kwayoyin halittar da ke cikin kashin kasusuwa su ne fashewa kuma kasa da 1% na sel din da ke cikin jini fashewa ce.

• Ciwon ƙwayar myelodysplastic da ba za a iya rarraba shi ba : Lambobin fashewa a cikin ɓarin ƙashi da jini na al'ada ne, kuma cutar ba ta ɗaya daga cikin cututtukan myelodysplastic.

• Ciwo na Myelodysplastic da ke haɗuwa da keɓaɓɓiyar ƙwayar cuta ta chromosome: Akwai ƙananan ƙwayoyin jini a cikin jini kuma mai haƙuri yana da karancin jini. Kasa da kashi 5 cikin 100 na sel a cikin kashin jini da jini bugu ne. Akwai takamaiman canji a cikin chromosome.

• Myelomonocytic leukemia na kullum (CMML): Duba taƙaitaccen akan Maganin Myelodysplastic / Myeloproliferative Neoplasms don ƙarin bayani.

Shekaru da maganin da suka gabata tare da chemotherapy ko radiation na shafar haɗarin cututtukan myelodysplastic.

Duk wani abu da zai kara maka hadarin kamuwa da cuta to ana kiran sa mai hadari. Samun haɗarin haɗari ba yana nufin cewa za ku kamu da cuta ba; ba tare da haɗarin abubuwan haɗari ba yana nufin cewa ba zaku sami cuta ba. Yi magana da likitanka idan kuna tsammanin kuna iya fuskantar haɗari. Abubuwan haɗari ga cututtukan myelodysplastic sun haɗa da masu zuwa:

• Jiyya na baya tare da chemotherapy ko radiation don cutar kansa.

• Kasancewa da wasu sinadarai, gami da hayakin taba, magungunan kashe kwari, takin zamani, da abubuwan narkewa kamar benzene.

• Kasancewa da ƙananan ƙarfe, kamar su mercury ko gubar.

Dalilin cututtukan myelodysplastic a yawancin marasa lafiya ba a san su ba.

Alamomi da alamomin ciwo na myelodysplastic sun haɗa da ƙarancin numfashi da jin kasala.

Ciwon ƙwayar cuta na Myelodysplastic galibi baya haifar da alamun farko ko alamomi. Ana iya samun su yayin gwajin jini na yau da kullun. Alamu da alamomin na iya faruwa ne ta sanadin ƙwayoyin myelodysplastic ko wasu yanayi. Duba tare da likitanka idan kuna da ɗayan masu zuwa:

• Rashin numfashi.

• Rashin rauni ko jin kasala.

• Samun fata wanda yake paler fiye da yadda aka saba.

• Aramar rauni ko zubar jini.

• Petechiae (lebur, tabo daidai a karkashin fata sanadiyyar zubar jini).

Ana amfani da gwaje-gwajen da ke bincikar jini da ƙashi a gano (gano) da kuma gano cututtukan myelodysplastic.

Za a iya amfani da waɗannan gwaje-gwajen da hanyoyin:

• Jarabawa ta jiki da tarihi: Jarabawa ce ta jiki don bincika alamomin lafiya gaba ɗaya, gami da bincika alamun cuta, kamar kumburi ko wani abu da kamar baƙon abu. Za a kuma ɗauki tarihin al'adun lafiyar marasa lafiya da cututtukan da suka gabata da magunguna.

• Cikakken ƙidayar jini (CBC) tare da banbanci: Hanyar da za'a zana samfurin jini kuma a bincika ta mai zuwa:

Yawan jajayen kwayoyin jini da platelets.

• Adadi da nau'in farin jini.

• Adadin haemoglobin (furotin da ke ɗauke da iskar oxygen) a cikin ƙwayoyin jinin jini.

• Yankin samfurin jini ya kunshi jajayen ƙwayoyin jini.

Kammala lissafin jini (CBC). Ana tattara jini ta hanyar sanya allura a cikin jijiya da kuma barin jini ya kwarara cikin bututu. Ana aika samfurin jini zuwa dakin gwaje-gwaje kuma ana kidaya ƙwayoyin jinin jini, fararen ƙwayoyin jini, da kuma platelets. Ana amfani da CBC don gwadawa, gano asali, da kuma lura da yanayi daban-daban.

• Shafar jinin gefe: Hanya ce wacce ake bincika samfurin jini don canje-canje a lamba, nau'in, siffa, da girman ƙwayoyin jini da ƙarfe da yawa a cikin jinin ja.

• Nazarin Cytogenetic: Gwajin dakin gwaje-gwaje wanda aka kirga chromosomes na kwayoyin halitta a cikin samfurin kasusuwan ƙashi ko jini kuma ana duba su don kowane canje-canje, kamar karye, ɓacewa, sake gyarawa, ko ƙarin ƙwayoyin cuta. Canje-canje a cikin wasu chromosomes na iya zama alamar cutar kansa. Ana amfani da nazarin Cytogenetic don taimakawa gano cutar kansa, shirya magani, ko gano yadda magani ke aiki.

• Nazarin ilimin sunadarai na jini: Hanya ce wacce ake bincikar samfurin jini don auna adadin wasu abubuwa, kamar su bitamin B12 da folate, wanda aka saki a cikin jini ta gabobi da kyallen takarda a jiki. Adadin abu na yau da kullun (mafi girma ko ƙasa da al'ada) na iya zama alamar cuta.

• Burin kasusuwan kasusuwa da kuma biopsy: Cire kasusuwan kasusuwa, jini, da karamin guntun kashi ta hanyar sanya allura mara kyau a cikin kashin hanji ko kashin mama. Wani masanin ilimin ɗan adam ya kalli kasusuwan kasusuwa, jini, da ƙashi a ƙarƙashin microscope don neman ƙwayoyin cuta mara kyau.

Burin kasusuwa da biopsy. Bayan an lasafta wani karamin yanki na fata, ana saka allurar kasusuwa ta kashin a cikin kashin hancin mara lafiyar. Ana cire samfurorin jini, kashi, da kashin nama don bincike a karkashin wani madubin likita.

Za'a iya yin gwaje-gwaje masu zuwa akan samfurin ƙwayar da aka cire:

• Immunocytochemistry: Gwajin gwaje-gwaje wanda ke amfani da kwayoyin cuta don bincika wasu antigens (alamomi) a cikin samfurin kasusuwan kasusuwan marasa lafiya. Magungunan rigakafi yawanci suna da alaƙa da enzyme ko fenti mai kyalli. Bayan kwayoyin sun hada da antigen a cikin kwayoyin sel din, sai a kunna enzyme ko rini, sannan za a iya ganin antigen a karkashin madubin likita. Irin wannan gwajin ana amfani dashi don taimakawa gano cutar kansa da kuma faɗi bambanci tsakanin cututtukan myelodysplastic, cutar sankarar bargo, da sauran yanayi.

• Immunophenotyping: Gwajin dakin gwaje-gwaje da ke amfani da kwayoyin cuta don gano kwayoyin cutar kansar dangane da nau'ikan antigens ko alamomi a saman sel. Ana amfani da wannan gwajin don taimakawa wajen tantance takamaiman nau'in cutar sankarar jini da sauran cututtukan jini.

• Gudun cytometry: Gwajin dakin gwaje-gwaje wanda ke auna yawan kwayoyin halitta a cikin samfurin, yawan kwayoyin rai a cikin samfurin, da wasu halaye na kwayoyin, kamar girman su, sifar su, da kuma kasancewar ciwace ciwace ciwace (ko wasu) Tantanin tantanin halitta Kwayoyin daga samfurin jinin mai haƙuri, kashin ƙashi, ko wasu kayan suna da datti tare da fenti mai kyalli, sanya shi a cikin ruwa, sannan a wuce ɗaya bayan ɗaya ta hanyar hasken haske. Sakamakon gwajin ya ta'allaka ne akan yadda ƙwayoyin da aka lalata tare da fenti mai kyalli ke amsa ga katangar haske. Ana amfani da wannan gwajin don taimakawa wajen ganowa da kuma sarrafa wasu nau'ikan cutar kansa, kamar cutar sankarar bargo da cutar lymphoma.

• KIFI (haske a cikin yanayin haɗuwa): Gwajin gwaje-gwaje da ake amfani dashi don kallo da ƙididdigar kwayoyin halitta ko chromosomes a cikin ƙwayoyin halitta da kyallen takarda. Ana yin sassan DNA wanda ke ɗauke da launuka masu kyalli a cikin dakin gwaje-gwaje kuma an ƙara su zuwa samfurin ƙwayoyin marasa lafiya ko kyallen takarda. Lokacin da wadannan sassan jikin DNA din da aka rina suka hade da wasu kwayoyin halittu ko bangarorin chromosomes a cikin samfurin, suna haskakawa idan aka kalleshi a karkashin madubin hangen nesa. Ana amfani da gwajin FISH don taimakawa wajen gano kansar da kuma taimakawa shirya magani.

Wasu dalilai suna tasiri hangen nesa da zaɓuɓɓukan magani.

Halin hangen nesa (damar dawowa) da zaɓuɓɓukan magani sun dogara da masu zuwa:

• Adadin kwayoyin fashewa a cikin kashin kashi.

• Ko daya ko fiye iri na kwayoyin halittar jini ya shafa.

• Ko mai haƙuri yana da alamu ko alamomin rashin jini, zubar jini, ko kamuwa da cuta.

• Ko mai haƙuri yana da ƙarancin haɗarin cutar sankarar bargo.

• Wasu canje-canje a cikin chromosomes.

• Ko dai cutar ta myelodysplastic ta faru ne bayan an yi amfani da cutar sankara ko kuma maganin cutar kansa.

• Shekaru da lafiyar lafiyar mai haƙuri.

Bayanin Zaɓin Jiyya

MAGANAN MAGANA

• Akwai nau'ikan magani iri daban-daban ga marasa lafiya da cututtukan myelodysplastic.

• Jiyya don cututtukan myelodysplastic sun haɗa da kulawa na tallafi, maganin ƙwayoyi, da kuma dasawa da kwayar halitta.

• Ana amfani da nau'i uku na daidaitaccen magani:

• Taimakon tallafi

• Magungunan ƙwayoyi

• Chemotherapy tare da dasawa da kwayar halitta

• Ana gwada sababbin nau'ikan magani a gwajin asibiti.

• Jiyya don cututtukan myelodysplastic na iya haifar da sakamako masu illa.

• Marasa lafiya na iya son yin tunani game da shiga cikin gwaji na asibiti.

• Marasa lafiya na iya shiga gwajin asibiti kafin, yayin, ko bayan fara jiyyarsu.

• Ana iya buƙatar gwaje-gwaje na gaba.

Akwai nau'ikan magani iri daban-daban ga marasa lafiya da cututtukan myelodysplastic.

Akwai nau'ikan magani daban-daban ga marasa lafiya da cututtukan myelodysplastic. Wasu jiyya suna daidaito (magani da ake amfani dashi yanzu), kuma wasu ana gwada su a gwajin asibiti. Gwajin gwajin magani shine binciken bincike wanda aka tsara don taimakawa inganta ingantattun jiyya na yanzu ko samun bayanai game da sababbin jiyya ga marasa lafiya da ciwon daji. Lokacin da gwaji na asibiti ya nuna cewa sabon magani ya fi magani na yau da kullun, sabon magani na iya zama daidaitaccen magani. Marasa lafiya na iya son yin tunani game da shiga cikin gwaji na asibiti. Wasu gwaji na asibiti ana buɗe su ne kawai ga marasa lafiyar da basu fara magani ba.

Jiyya don cututtukan myelodysplastic sun haɗa da kulawa na tallafi, maganin ƙwayoyi, da kuma dasawa da kwayar halitta.

Marasa lafiyar da ke fama da cututtukan myelodysplastic waɗanda ke da alamomin da ƙananan ƙididdigar jini ke haifarwa ana ba su kulawa ta taimako don sauƙaƙe alamun cutar da haɓaka ƙimar rayuwa. Ana iya amfani da maganin ƙwayoyi don rage ci gaban cutar. Wasu marasa lafiya za a iya warke su tare da jiyya mai tsanani tare da cutar sankara ta hanyar bin kwayar halitta ta hanyar amfani da ƙwayoyin sel daga mai bayarwa.

Ana amfani da nau'i uku na daidaitaccen magani:

Taimakon tallafi

Ana ba da kulawa na tallafi don rage matsalolin da cutar ta haifar ko kuma maganinta. Taimako na tallafi na iya haɗa da masu zuwa:

• Maganin dasa jini

Yin karin jini (ƙarin jini) hanya ce ta ba da jajayen jini, fararen ƙwayoyin jini, ko platelets don maye gurbin ƙwayoyin jinin da cuta ko magani suka lalata. Ana ba da ƙarin jini a lokacin da ƙidayar ƙanƙan jini ta ragu kuma alamun ko alamun alamun rashin jini, kamar ƙarancin numfashi ko jin kasala sosai, suna faruwa. Yawancin lokaci ana ba da jinin platelet lokacin da mara lafiya ke zubar da jini, yana yin aikin da zai iya haifar da zub da jini, ko kuma lokacin da ƙarancin platelet ya yi ƙasa ƙwarai.

Marasa lafiya da ke karɓar ƙarin jini da yawa na iya samun lalacewar nama da gabobin jiki ta hanyar ƙarin baƙin ƙarfe. Wadannan marasa lafiya za a iya bi da su tare da maganin baƙin ƙarfe don cire ƙarin baƙin ƙarfe daga jini.

• Ma'aikatan motsa jiki na Erythropoiesis

Erythropoiesis-stimulating agents (ESAs) za'a iya ba shi don ƙara yawan ƙwayoyin jinin jini ja da jiki yayi da kuma rage tasirin anemia. Wasu lokuta ana ba da mahimmancin tasirin mulkin mallaka (G-CSF) tare da ESA don taimakawa aikin kulawa mafi kyau.

• Maganin rigakafi

Ana iya ba da maganin rigakafi don yaƙi da kamuwa da cuta.

Magungunan ƙwayoyi

• Lenalidomide

Marasa lafiya da ke fama da cutar ta myelodysplastic da ke da alaƙa da keɓaɓɓiyar ƙwayoyin cuta ta del (5q) waɗanda ke buƙatar ƙarin jinin ƙwayoyin jini mai yawa ana iya bi da su tare da lenalidomide. Ana amfani da Lenalidomide don rage buƙatun ƙarin jini.

• Immunosuppressive far

Antithymocyte globulin (ATG) yana aiki don murƙushe ko raunana tsarin garkuwar jiki. Ana amfani dashi don rage buƙatun ƙarin jini.

• Azacitidine da decitabine

Ana amfani da Azacitidine da decitabine don magance cututtukan myelodysplastic ta hanyar kashe ƙwayoyin da ke rarraba cikin sauri. Hakanan suna taimaka wa kwayoyin halittar da ke cikin kwayar halitta su yi aiki yadda ya kamata. Jiyya tare da azacitidine da decitabine na iya rage ci gaban cututtukan myelodysplastic zuwa myeloid cutar sankarar bargo.

• Chemotherapy da aka yi amfani da shi a cikin cutar sankarar bargo na myeloid (AML)

Marasa lafiya da ke fama da cutar sankarau da yawan fashewar abubuwa a cikin kashinsu suna da babban haɗarin cutar sankarar bargo. Ana iya bi da su tare da irin wannan tsarin ilimin kimiya wanda aka yi amfani da shi ga marasa lafiya da cutar sankarar myeloid mai tsanani.

Chemotherapy tare da dasawa da kwayar halitta

Ana ba da magani don kashe ƙwayoyin kansa. Kwayoyin lafiya, gami da ƙwayoyin halitta masu jini, suma ana lalata su ta hanyar maganin kansa. Dasawar sel shine magani don maye gurbin kwayoyin halitta. Ana cire ƙwayoyin sari (ƙwayoyin jinin da basu balaga ba) daga cikin jinin ko ƙashin ƙashin mara lafiya ko mai bayarwa kuma ana daskarar dasu ana adana su. Bayan mai haƙuri ya gama shan magani, sai a narke ƙwayoyin ƙwayoyin da aka adana kuma a mayar da su ga mai haƙuri ta hanyar jiko. Waɗannan ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin na ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin na ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin na ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin na ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin magungunan za a ɗibar

Wannan maganin bazai yi aiki sosai a cikin marasa lafiya ba wanda cutar sankarau ta haifar da cutar kansa.

Dasawar dasa kara (Mataki na 1): Ana ɗaukar jini daga jijiya a hannun mai bayarwa. Mai haƙuri ko wani mutum na iya zama mai ba da gudummawa. Jinin yana gudana ta cikin injin da ke cire ƙwayoyin sel. Sannan jinin yana dawowa ga mai bayarwa ta wata jijiya a daya hannun. (Mataki 2): Mai haƙuri yana karɓar magani don kashe ƙwayoyin halitta. Mai haƙuri na iya karɓar maganin radiation (ba a nuna ba). (Mataki na 3): Mai haƙuri yana karɓar ƙwayoyin sel ta hanyar catheter da aka sanya a cikin jijiyoyin jini a cikin kirji.

Ana gwada sababbin nau'ikan magani a gwajin asibiti.

Ana samun bayani game da gwaji na asibiti daga gidan yanar gizon NCI.

Jiyya don cututtukan myelodysplastic na iya haifar da sakamako masu illa.

Don bayani game da illolin da cutar ta kansar ta haifar, duba shafin mu na Side Side.

Marasa lafiya na iya son yin tunani game da shiga cikin gwaji na asibiti.

Ga wasu marasa lafiya, shiga cikin gwaji na asibiti na iya zama mafi kyawun zaɓin magani. Gwajin gwaji wani bangare ne na aikin binciken cutar kansa. Ana yin gwaje-gwajen asibiti don gano ko sabbin maganin cutar daji suna da lafiya da tasiri ko kuma sun fi magani na yau da kullun.

Yawancin yau da kullun na yau da kullun don cutar kansa sun dogara ne akan gwajin asibiti na farko. Marasa lafiya da ke cikin gwaji na asibiti na iya karɓar daidaitaccen magani ko kuma su kasance cikin farkon waɗanda za su karɓi sabon magani.

Marasa lafiya da ke shiga cikin gwaji na asibiti suma suna taimakawa inganta hanyar da za a bi da kansar a nan gaba. Koda lokacin gwajin asibiti bai haifar da sababbin magunguna ba, sau da yawa sukan amsa mahimman tambayoyi kuma suna taimakawa ci gaba da bincike gaba.

Marasa lafiya na iya shiga gwajin asibiti kafin, yayin, ko bayan fara jiyyarsu.

Wasu gwaji na asibiti kawai sun haɗa da marasa lafiya waɗanda ba su sami magani ba tukuna. Sauran gwaje-gwajen suna gwada jiyya ga marasa lafiya waɗanda cutar kansa ba ta samu sauki ba. Hakanan akwai gwaji na asibiti da ke gwada sabbin hanyoyin dakatar da cutar kansa daga sake dawowa (dawowa) ko rage tasirin maganin kansar.

Gwajin gwaji na gudana a sassa da yawa na ƙasar. Bayani game da gwajin asibiti wanda NCI ke tallafawa ana iya samun shi akan shafin binciken gwaji na NCI. Ana iya samun gwajin gwaji na asibiti wanda wasu kungiyoyi ke tallafawa akan gidan yanar gizon ClinicalTrials.gov.

Ana iya buƙatar gwaje-gwaje na gaba.

Za a iya maimaita wasu gwaje-gwajen da aka yi don gano cutar kansa ko don gano matakin cutar kansa. Za a maimaita wasu gwaje-gwaje don ganin yadda magani ke aiki. Shawarwari game da ci gaba, canji, ko dakatar da magani na iya dogara ne da sakamakon waɗannan gwaje-gwajen.

Wasu daga cikin gwaje-gwajen za a ci gaba da yi daga lokaci zuwa lokaci bayan an gama jiyya. Sakamakon waɗannan gwaje-gwajen na iya nuna idan yanayin ku ya canza ko kuma idan kansar ta sake dawowa (dawo). Wadannan gwaje-gwajen wasu lokuta ana kiran su gwaje-gwaje na gaba ko dubawa.

Zaɓuɓɓukan Jiyya don Ciwan Myelodysplastic

Don bayani game da jiyya da aka jera a ƙasa, duba sashin Kula da Zaɓin Jiyya.

Tabbatattun Zaɓuɓɓukan Jiyya don Ciwan Myelodysplastic

Zaɓuɓɓukan magani na yau da kullun don cututtukan myelodysplastic sun haɗa da:

• Taimako na tallafi tare da ɗaya ko fiye na masu zuwa:

• Maganin dasa jini

• Erythropoiesis masu motsa jiki.

• Maganin rigakafi.

• Jiyya don jinkirta ci gaba zuwa cutar sankarar myeloid mai tsanani (AML):

• Lenalidomide.

• Immunosuppressive far.

• Azacitidine da decitabine.

• Chemotherapy da aka yi amfani da shi a cikin cutar sankarar myeloid mai tsanani.

• Chemotherapy tare da dasawa da kwayar halitta.

Jiyya na Maganin Myeloid Neoplasms

Marasa lafiya waɗanda aka bi da su a baya tare da chemotherapy ko radiation na iya haɓaka myeloid neoplasms da suka danganci wannan maganin. Zaɓuɓɓukan jiyya daidai suke da na sauran cututtukan myelodysplastic.

Yi amfani da binciken bincikenmu na asibiti don nemo NCI na goyan bayan gwajin asibiti wanda ke karɓar marasa lafiya. Kuna iya bincika gwaji dangane da nau'in ciwon daji, shekarun mai haƙuri, da kuma inda ake yin gwajin. Ana samun cikakken bayani game da gwaji na asibiti.

Zaɓuɓɓukan Jiyya don Maɗaukaki ko ractarfin Ciwan Myelodysplastic

Don bayani game da jiyya da aka jera a ƙasa, duba sashin Kula da Zaɓin Jiyya.

Babu daidaitaccen magani don ƙyama ko ɓarkewar ƙwayoyin myelodysplastic. Marasa lafiya wanda ciwon kansa ba ya karɓar magani ko ya dawo bayan jiyya na iya son shiga cikin gwajin asibiti.

Yi amfani da binciken bincikenmu na asibiti don nemo NCI na goyan bayan gwajin asibiti wanda ke karɓar marasa lafiya. Kuna iya bincika gwaji dangane da nau'in ciwon daji, shekarun mai haƙuri, da kuma inda ake yin gwajin. Ana samun cikakken bayani game da gwaji na asibiti.

Don Moreara Koyo Game da Ciwon Myelodysplastic Syndromes

Don ƙarin bayani daga Cibiyar Cancer ta cerasa game da cututtukan myelodysplastic, duba mai zuwa:

• Tattara Kwayoyin Halitta mai Yin jini

Don cikakkun bayanai game da cutar kansa da sauran albarkatu daga Cibiyar Cancer ta Kasa, duba mai zuwa:

• Game da Ciwon daji

• Tsayawa

• Chemotherapy da ku: Tallafi ga Mutanen da ke Ciwon daji

• Radiation Far da Kai: Taimako ga Mutane Tare da Ciwon daji

• Yin fama da Ciwon daji

• Tambayoyi don Tambayar Doctor game da Ciwon daji

• Don Tsira da Kulawa

• Game da Wannan Taƙaitaccen