Types/myeloproliferative/patient/mds-mpd-treatment-pdq

Myelodysplastic / Myeloproliferative Neoplasms Treatment (®) –Tsarin Mara lafiya

Janar Bayani Game da Myelodysplastic / Myeloproliferative Neoplasms

MAGANAN MAGANA

• Myelodysplastic / myeloproliferative neoplasms rukuni ne na cututtuka wanda ɓarin ƙashi yake sanya fararen ƙwayoyin jini da yawa.

• Myelodysplastic / myeloproliferative neoplasms suna da siffofi na duka myelodysplastic syndromes da myeloproliferative neoplasms.

• Akwai nau'ikan nau'ikan myelodysplastic / myeloproliferative neoplasms.

• Ana amfani da gwaje-gwajen da ke bincikar jini da ƙashi don gano (gano) da kuma gano myelodysplastic / myeloproliferative neoplasms.

Myelodysplastic / myeloproliferative neoplasms rukuni ne na cututtuka wanda ɓarin ƙashi yake sanya fararen ƙwayoyin jini da yawa.

Myelodysplastic / myeloproliferative neoplasms cututtuka ne na jini da jijiyoyin ƙashi.

Anatomy na kashi. Kashin ya kunshi karamin kashi, kashin baya, da kashin baya. Karamin kashi yana yin layin waje na ƙashi. Ana samun kashin Spongy galibi a ƙarshen ƙasusuwa kuma yana ɗauke da jajaja. Ana samun kasusuwan kasusuwa a tsakiyar mafi yawan kasusuwa kuma yana da jijiyoyi da yawa. Akwai kashin kashi biyu: ja da rawaya. Jan kashin jini ya ƙunshi ƙwayoyin jini wanda zai iya zama jajayen ƙwayoyin jini, fararen ƙwayoyin jini, ko platelets. An sanya kasusuwan rawaya mafi yawan mai.

A yadda aka saba, ƙashin ƙasusuwa yana sa ƙwayoyin jini na jini (ƙwayoyin da ba su balaga ba) waɗanda suka zama ƙwararrun ƙwayoyin jini a kan lokaci. Stemwayar ƙwayar ƙwayar jini na iya zama ƙwayar ƙwayar myeloid ko ƙwayar ƙwayar ƙwayar lymphoid. Kwayar kwayar lymphoid ta zama farin jini. Kwayar kara kuzari ta myeloid ta zama ɗayan nau'ikan nau'ikan ƙwayoyin jini uku masu girma:

• Jajayen jini wadanda suke daukar iskar oxygen da sauran abubuwa zuwa dukkan kyallen takarda.

• Farin jini wanda ke yakar kamuwa da cuta.

• Platelets wadanda suke samar da daskararren jini dan tsaida zubar jini.

Ci gaban kwayar jini. Kwayar sel ta jini tana wucewa ta matakai da yawa don zama jajayen jini, platelet, ko kuma farin jini.

Myelodysplastic / myeloproliferative neoplasms suna da siffofi na duka myelodysplastic syndromes da myeloproliferative neoplasms.

A cikin cututtukan myelodysplastic, ƙwayoyin sel na jini ba su girma cikin lafiyayyun ƙwayoyin jini, farin ƙwayoyin jini, ko platelets. Kwayoyin jinin da basu balaga ba, wadanda ake kira blasts, basa aiki yadda yakamata su mutu a cikin kashin kashi ko kuma jim kadan da shiga cikin jini. A sakamakon haka, akwai karancin jan jinin jini, da fararen kwai, da kuma platelets.

A cikin cututtukan myeloproliferative, mafi girma fiye da al'ada yawan ƙwayoyin ƙwayoyin jini suna zama ɗaya ko fiye na ƙwayoyin jini kuma adadin ƙwayoyin jini yana ƙaruwa a hankali.

Wannan taƙaitaccen bayani ne game da neoplasms waɗanda ke da siffofin duka cututtukan myelodysplastic da na myeloproliferative. Duba taƙaitattun masu zuwa don ƙarin bayani game da cututtuka masu alaƙa:

• Jiyya na Ciwan Myelodysplastic

• Magungunan Neoplasms na Myeloproliferative na kullum

• Magungunan cutar sankarar bargo na zamani

Akwai nau'ikan nau'ikan myelodysplastic / myeloproliferative neoplasms.

Manyan nau'ikan 3 na myelodysplastic / myeloproliferative neoplasms sun hada da masu zuwa:

• Myelomonocytic cutar sankarar bargo (CMML)

• Yaran yara masu cutar sankarar bargo (JMML).

• Atypical na kullum myelogenous cutar sankarar bargo (CML).

Lokacin da myelodysplastic / myeloproliferative neoplasm bai yi daidai da ɗayan waɗannan nau'ikan ba, ana kiran shi myelodysplastic / myeloproliferative neoplasm, wanda ba za a iya rarraba shi ba (MDS / MPN-UC).

Myelodysplastic / myeloproliferative neoplasms na iya ci gaba zuwa cutar sankarar bargo.

Ana amfani da gwaje-gwajen da ke bincikar jini da ƙashi don gano (gano) da kuma gano myelodysplastic / myeloproliferative neoplasms.

Za a iya amfani da waɗannan gwaje-gwajen da hanyoyin:

• Jarabawa ta jiki da tarihi: Jarabawa ce ta jiki don bincika alamomin kiwon lafiya gaba ɗaya, gami da bincika alamun cuta kamar ƙara girman ciki da hanta. Za a kuma ɗauki tarihin al'adun lafiyar marasa lafiya da cututtukan da suka gabata da magunguna.

• Cikakken ƙidayar jini (CBC) tare da banbanci: Hanyar da za'a zana samfurin jini kuma a bincika ta mai zuwa:

• Yawan jajayen kwayoyin jini da platelets.

• Adadi da nau'in farin jini.

• Adadin haemoglobin (furotin da ke ɗauke da iskar oxygen) a cikin ƙwayoyin jinin jini.

• Yankin samfurin ya kunshi jajayen ƙwayoyin jini.

Kammala lissafin jini (CBC). Ana tattara jini ta hanyar sanya allura a cikin jijiya da kuma barin jini ya kwarara cikin bututu. Ana aika samfurin jini zuwa dakin gwaje-gwaje kuma ana kidaya ƙwayoyin jinin jini, fararen ƙwayoyin jini, da kuma platelets. Ana amfani da CBC don gwadawa, gano asali, da kuma lura da yanayi daban-daban.

• Shafar jinin gefe: Hanya ce wacce ake bincika samfurin jini don ƙwayoyin fashewa, lamba da nau'ikan fararen ƙwayoyin jini, da yawan platelets, da canje-canje a cikin surar ƙwayoyin jini.

• Nazarin ilimin sunadarai na jini: Hanya ce wacce ake bincikar samfurin jini don auna adadin wasu abubuwa da aka saki a cikin jini ta gabobi da kayan aiki a jiki. Adadin abu na yau da kullun (mafi girma ko ƙasa da al'ada) na iya zama alamar cuta.

• Burin kasusuwan kasusuwa da biopsy: Cire karamin guntun kashi da kashin kashi ta hanyar sanya allura a cikin kashin hanji ko kashin mama. Kwararren likitan kwalliya ya kalli samfurin kasusuwa da kasusuwa a karkashin madubin hangen nesa don neman kwayoyin halitta marasa kyau.

Burin kasusuwa da biopsy. Bayan an lasafta wani karamin yanki na fata, ana saka allurar kasusuwa ta kashin a cikin kashin hancin mara lafiyar. Ana cire samfurorin jini, kashi, da kashin nama don bincike a karkashin wani madubin likita.

Za'a iya yin gwaje-gwaje masu zuwa akan samfurin ƙwayar da aka cire:

• Nazarin Cytogenetic: Gwajin dakin gwaje-gwaje wanda ake kirga chromosomes na kwayoyin halitta a cikin samfurin kashin ƙashi ko jini kuma ana bincika su kowane canje-canje, kamar karye, ɓacewa, sake gyarawa, ko ƙarin ƙwanƙwanni. Canje-canje a cikin wasu chromosomes na iya zama alamar cutar kansa. Ana amfani da nazarin Cytogenetic don taimakawa gano cutar kansa, shirya magani, ko gano yadda magani ke aiki. Kwayoyin cutar kansa a cikin myelodysplastic / myeloproliferative neoplasms basu dauke da chromosome na Philadelphia wanda yake a cikin cutar sankarar bargo mai tsafta.

• Immunocytochemistry: Gwajin gwaje-gwaje wanda ke amfani da kwayoyin cuta don bincika wasu antigens (alamomi) a cikin samfurin kasusuwan kasusuwan marasa lafiya. Magungunan rigakafi yawanci suna da alaƙa da enzyme ko fenti mai kyalli. Bayan kwayoyin sun hada da antigen a cikin samfurin kashin kashin mara lafiyan, an kunna enzyme ko rini, sannan ana iya ganin antigen a karkashin madubin hangen nesa. Ana amfani da irin wannan gwajin don taimakawa wajen gano cutar kansa da kuma faɗi bambanci tsakanin myelodysplastic / myeloproliferative neoplasms, cutar sankarar bargo, da sauran yanayi.

Na kullum Myelomonocytic cutar sankarar bargo

MAGANAN MAGANA

• Myelomonocytic leukemia na yau da kullun wata cuta ce wacce ake yin yawancin myelocytes da monocytes (ƙwayoyin jinin farin da basu balaga ba) a cikin kashin ƙashi.

• Yawan tsufa da kasancewa namiji suna haɗarin haɗarin cutar sankarar bargo na sankarau.

• Alamomi da alamomin cutar sankarar bargo na myelomonocytic leukemia na yau da kullun sun hada da zazzabi, ragin kiba, da jin kasala sosai.

• Wasu dalilai suna tasiri hangen nesa (damar dawowa) da zaɓuɓɓukan magani.

Myelomonocytic leukemia na yau da kullun wata cuta ce wacce ake yin yawancin myelocytes da monocytes (ƙwayoyin jinin farin da basu balaga ba) a cikin kashin ƙashi.

A cikin cutar sankarar myelomonocytic na kullum (CMML), jiki yana gaya wa ƙwayoyin jini da yawa su zama nau'ikan farin jini guda biyu da ake kira myelocytes da monocytes. Wasu daga cikin wadannan ƙwayoyin sel ɗin ba su taɓa zama cikakkun ƙwayoyin farin jini ba. Wadannan fararen kwayoyin jinin da basu balaga ba ana kiran su da harbe-harbe. Da shigewar lokaci, myelocytes, monocytes, da kuma hargitsi sun fitar da jajayen ƙwayoyin jini da platelet a cikin ɓarin kashi. Lokacin da wannan ya faru, kamuwa da cuta, ƙarancin jini, ko saurin zubar jini na iya faruwa.

Yawan tsufa da kasancewa namiji suna haɗarin haɗarin cutar sankarar bargo na sankarau.

Duk wani abu da zai kara muku damar kamuwa da cuta to ana kiransa mai hadari. Abubuwan haɗarin haɗari ga CMML sun haɗa da masu zuwa:

• Yawan shekaru.
• Kasancewa namiji.
• Kasancewa da wasu abubuwa a wurin aiki ko a muhalli.
• Kasancewa ga radiation.
• Maganin da ya gabata tare da wasu magungunan anticancer.

Alamomi da alamomin cutar sankarar bargo na myelomonocytic leukemia na yau da kullun sun hada da zazzabi, ragin kiba, da jin kasala sosai.

Wadannan da wasu alamu da alamomin na iya faruwa ne ta hanyar CMML ko ta wasu yanayi. Duba tare da likitanka idan kuna da ɗayan masu zuwa:

• Zazzabi ba tare da sananne dalili ba.
• Kamuwa da cuta.
• Jin kasala sosai.
• Rashin nauyi ba tare da wani dalili da aka sani ba.
• Aramar rauni ko zubar jini.
• Jin zafi ko jin cikewar ƙasa da haƙarƙarin.

Wasu dalilai suna tasiri hangen nesa (damar dawowa) da zaɓuɓɓukan magani.

Hannun gaba (damar dawowa) da zaɓuɓɓukan magani na CMML sun dogara da masu zuwa:

• Adadin farin jini ko platelets a cikin jini ko kashin kashi.

• Ko mara lafiyan yana fama da karancin jini.

• Yawan fashewar abubuwa a cikin jini ko kashin kashi.

• Adadin haemoglobin a cikin kwayoyin jini.

• Ko akwai wasu canje-canje a cikin chromosomes.

Ciwon yara Myelomonocytic Cutar sankarar bargo

MAGANAN MAGANA

• Yarinyar myelomonocytic cutar sankarar bargo cuta ce ta yara wanda a ciki ake samun myelocytes da monocytes da yawa (ƙwayoyin jinin da ba su balaga ba) a cikin ɓarke.

• Alamomi da alamomin cutar sankarar bargo na yara sun hada da zazzabi, rage nauyi, da jin kasala sosai.

• Wasu dalilai suna tasiri hangen nesa (damar dawowa) da zaɓuɓɓukan magani.

Yarinyar myelomonocytic cutar sankarar bargo cuta ce ta yara wanda a ciki ake samun myelocytes da monocytes da yawa (ƙwayoyin jinin da ba su balaga ba) a cikin ɓarke.

Yammacin myelomonocytic leukemia (JMML) shine cutar kansa mafi ƙarancin yara wanda ke faruwa sau da yawa a cikin yara ƙanana da shekaru 2. Yaran da ke da nau'in neurofibromatosis nau'in 1 da maza suna da haɗarin ƙarancin cutar sankarau na yara.

A cikin JMML, jiki yana gaya wa ƙwayoyin jini da yawa su zama ƙwayoyin farin jini guda biyu da ake kira myelocytes da monocytes. Wasu daga cikin wadannan ƙwayoyin sel ɗin ba su taɓa zama cikakkun ƙwayoyin farin jini ba. Wadannan fararen kwayoyin jinin da basu balaga ba ana kiran su da harbe-harbe. Da shigewar lokaci, myelocytes, monocytes, da kuma hargitsi sun fitar da jajayen ƙwayoyin jini da platelet a cikin ɓarin kashi. Lokacin da wannan ya faru, kamuwa da cuta, ƙarancin jini, ko saurin zubar jini na iya faruwa.

Alamomi da alamomin cutar sankarar bargo na yara sun hada da zazzabi, rage nauyi, da jin kasala sosai.

Wadannan da wasu alamu da alamomi na iya haifar da JMML ko ta wasu yanayi. Duba tare da likitanka idan kuna da ɗayan masu zuwa:

• Zazzabi ba tare da sananne dalili ba.

• Samun cututtuka, kamar mashako ko tonsillitis.

• Jin kasala sosai.

• Aramar rauni ko zubar jini.

• Rushewar fata.

• Swellingwanƙwasa ƙwayoyin lymph a cikin wuya, maras kyau, ciki, ko makwancin ciki.

• Jin zafi ko jin cikewar ƙasa da haƙarƙarin.

Wasu dalilai suna tasiri hangen nesa (damar dawowa) da zaɓuɓɓukan magani.

Hasashen (damar dawowa) da zaɓuɓɓukan magani don JMML sun dogara da masu zuwa:

• Shekarun yaro a ganewar asali

• Yawan platelets a cikin jini.

• Adadin wani nau'i na haemoglobin a cikin ƙwayoyin jinin jini.

Atypical Chronic Myelogenous cutar sankarar bargo

MAGANAN MAGANA

• Atypical chronic myelogenous leukemia wata cuta ce wacce ake yin yawancin granulocytes (ƙwayoyin jinin farin da basu balaga ba) a cikin kashin ƙashi.

• Alamomi da alamomi na cutar sankarar bargo mai haɗari marasa haɗari sun haɗa da raunin rauni ko zubar jini da jin kasala da rauni.

• Wasu dalilai suna shafar hangen nesa (damar dawowa).

Atypical chronic myelogenous leukemia wata cuta ce wacce ake yin yawancin granulocytes (ƙwayoyin jinin farin da basu balaga ba) a cikin kashin ƙashi.

A cikin cutar sankarar bargo (CML), jiki yana gaya wa ƙwayoyin jini da yawa su zama nau'in farin jini da ake kira granulocytes. Wasu daga cikin wadannan ƙwayoyin sel ɗin ba su taɓa zama cikakkun ƙwayoyin farin jini ba. Wadannan fararen kwayoyin jinin da basu balaga ba ana kiran su da harbe-harbe. Bayan lokaci, granulocytes da fashewar abubuwa sun taru sun fitar da jajayen ƙwayoyin jini da platelet a cikin ɓarin kashi.

Kwayoyin cutar sankarar bargo a cikin CML da CML marasa kyau suna kama da juna a ƙarƙashin madubin likita. Koyaya, a cikin CML wanda bashi da tushe wani canjin chromosome, wanda ake kira "Philadelphia chromosome" baya nan.

Alamomi da alamomi na cutar sankarar bargo mai haɗari marasa haɗari sun haɗa da raunin rauni ko zubar jini da jin kasala da rauni.

Wadannan da sauran alamu da alamomin na iya faruwa ne ta sanadiyar CML ko kuma ta wasu yanayi. Duba tare da likitanka idan kuna da ɗayan masu zuwa:

• Rashin numfashi.

• Fata mai haske

• Jin kasala sosai da rauni.

• Aramar rauni ko zubar jini.

• Petechiae (lebur, tabo daidai a karkashin fata sanadiyyar zubar jini).

• Jin zafi ko jin cikewar ƙasa da haƙarƙarin a gefen hagu.

Wasu dalilai suna shafar hangen nesa (damar dawowa).

Hannun gaba (damar samun sauki) na mara illa ga CML ya dogara ne da adadin jan jinin jini da platelets a cikin jini.

Myelodysplastic / Myeloproliferative Neoplasm, Ba za a iya rarraba shi ba

MAGANAN MAGANA

• Myelodysplastic / myeloproliferative neoplasm, wanda ba za a iya rabuwa da shi ba, cuta ce da ke da fasali na cututtukan myelodysplastic da na myeloproliferative amma ba mai cutar myelomonocytic leukemia, yara masu fama da cutar sankarar bargo, ko atypical chronic myelogenous leukemia.

• Alamomi da alamomi na myelodysplastic / myeloproliferative neoplasm, wanda ba za a iya tantance shi ba, sun hada da zazzabi, ragin nauyi, da jin kasala sosai.

Myelodysplastic / myeloproliferative neoplasm, wanda ba za a iya rabuwa da shi ba, cuta ce da ke da fasali na cututtukan myelodysplastic da na myeloproliferative amma ba mai cutar myelomonocytic leukemia, yara masu fama da cutar sankarar bargo, ko atypical chronic myelogenous leukemia.

A cikin myelodysplastic / myeloproliferative neoplasm, wanda ba za a iya rarraba shi ba (MDS / MPD-UC), jiki yana gaya wa ƙwayoyin jini da yawa su zama jajayen jini, fararen ƙwayoyin jini, ko platelets. Wasu daga cikin wadannan ƙwayoyin sel ɗin jinin basu taɓa zama tsofaffin ƙwayoyin jini ba. Waɗannan ƙwayoyin jinin da ba su balaga ba ana kiransu fashewa. Da shigewar lokaci, ƙwayoyin jinin da ba su dace ba da hargitsi a cikin ɓarke ​​sun fitar da lafiyayyun ƙwayoyin jini, da fararen ƙwayoyin jini, da platelets.

MDS / MPN-UC cuta ce mai saurin gaske. Saboda yana da wuya, ba a san abubuwan da ke shafar haɗari da hangen nesa ba.

Alamomi da alamomi na myelodysplastic / myeloproliferative neoplasm, wanda ba za a iya tantance shi ba, sun hada da zazzabi, ragin nauyi, da jin kasala sosai.

Wadannan da sauran alamu da alamun cutar na iya haifar da MDS / MPN-UC ko ta wasu yanayi. Duba tare da likitanka idan kuna da ɗayan masu zuwa:

• Zazzabi ko yawan kamuwa da cuta.

• Rashin numfashi.

• Jin kasala sosai da rauni.

• Fata mai haske

• Aramar rauni ko zubar jini.

• Petechiae (lebur, tabo daidai a karkashin fata sanadiyyar zubar jini).

• Jin zafi ko jin cikewar ƙasa da haƙarƙarin.

Matakai na Myelodysplastic / Myeloproliferative Neoplasms

MAGANAN MAGANA

• Babu daidaitaccen tsarin tsarkewa don myelodysplastic / myeloproliferative neoplasms.

Babu daidaitaccen tsarin tsarkewa don myelodysplastic / myeloproliferative neoplasms.

Staging hanya ce da ake amfani da ita don gano yadda cutar kansa ta bazu. Babu daidaitaccen tsarin tsarkewa don myelodysplastic / myeloproliferative neoplasms. Jiyya ya dogara ne akan nau'in myelodysplastic / myeloproliferative neoplasm da mai haƙuri ke dashi. Yana da mahimmanci a san nau'in don shirya magani.

Bayanin Zaɓin Jiyya

MAGANAN MAGANA

• Akwai nau'ikan magani daban-daban ga marasa lafiya tare da myelodysplastic / myeloproliferative neoplasms.

• Ana amfani da nau'i biyar na daidaitaccen magani:

• Chemotherapy

• Sauran maganin magani

• Dasawar dasa kara

• Taimakon tallafi

• Ciwon da aka yi niyya

• Ana gwada sababbin nau'ikan magani a gwajin asibiti.

• Jiyya don myelodysplastic / myeloproliferative neoplasms na iya haifar da sakamako masu illa.

• Marasa lafiya na iya son yin tunani game da shiga cikin gwaji na asibiti.

• Marasa lafiya na iya shiga gwajin asibiti kafin, lokacin, ko bayan fara maganin cutar kansa.

• Ana iya buƙatar gwaje-gwaje na gaba.

Akwai nau'ikan magani daban-daban ga marasa lafiya tare da myelodysplastic / myeloproliferative neoplasms.

Akwai nau'ikan jiyya iri daban-daban ga marasa lafiya da keɓaɓɓen ƙwayoyin cuta na myelodysplastic / myeloproliferative. Wasu jiyya suna daidaito (magani da ake amfani dashi yanzu), kuma wasu ana gwada su a gwajin asibiti. Gwajin gwajin magani shine binciken bincike wanda aka tsara don taimakawa inganta ingantattun jiyya na yanzu ko samun bayanai game da sababbin jiyya ga marasa lafiya da ciwon daji. Lokacin da gwaji na asibiti ya nuna cewa sabon magani ya fi magani na yau da kullun, sabon magani na iya zama daidaitaccen magani. Marasa lafiya na iya son yin tunani game da shiga cikin gwaji na asibiti. Wasu gwaji na asibiti ana buɗe su ne kawai ga marasa lafiyar da basu fara magani ba.

Ana amfani da nau'i biyar na daidaitaccen magani:

Chemotherapy

Chemotherapy magani ne na cutar kansa wanda ke amfani da magunguna don dakatar da haɓakar ƙwayoyin kansa, ko dai ta hanyar kashe ƙwayoyin ko ta hana su rarraba. Lokacin da ake shan chemotherapy ta baki ko allura a cikin jijiya ko tsoka, magungunan suna shiga cikin jini kuma zasu iya kaiwa ga kwayoyin cutar kansa a cikin jiki duka (systemotherapy chemotherapy). Lokacin da aka sanya chemotherapy kai tsaye zuwa cikin ruwa mai ruɓaɓɓen ciki, gaɓoɓi, ko rami na jiki kamar ciki, magungunan yawanci suna shafar ƙwayoyin kansa ne a waɗancan yankuna. Hanyar da ake ba da cutar sankara ta dogara da nau'in da matakin cutar kansa. Haɗaɗɗiyar cutar sanadiyyar magani magani ne ta amfani da fiye da ɗaya maganin ƙwayar cutar kansa.

Duba Magunguna da Aka Amince dasu don Ciwon Myeloproliferative Neoplasms don ƙarin bayani.

Sauran maganin magani

13-cis retinoic acid magani ne mai kama da bitamin wanda ke jinkirta ikon kansar don yin ƙarin ƙwayoyin kansa kuma yana canza yadda waɗannan ƙwayoyin suke kama da aiki.

Dasawar dasa kara

Ana ba da magani don kashe ƙwayoyin cuta ko ƙwayoyin kansa. Kwayoyin lafiya, gami da ƙwayoyin halitta masu jini, suma ana lalata su ta hanyar maganin kansa. Dasawar sel shine magani don maye gurbin kwayoyin halitta. Ana cire ƙwayoyin sari (ƙwayoyin jinin da basu balaga ba) daga cikin jinin ko ƙashin ƙashin mara lafiya ko mai bayarwa kuma ana daskarar dasu ana adana su. Bayan mai haƙuri ya gama shan magani, sai a narke ƙwayoyin ƙwayoyin da aka adana kuma a mayar da su ga mai haƙuri ta hanyar jiko. Waɗannan ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin na ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin na ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin na ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin na ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin magungunan za a ɗibar

Dasawar dasa kara (Mataki na 1): Ana ɗaukar jini daga jijiya a hannun mai bayarwa. Mai haƙuri ko wani mutum na iya zama mai ba da gudummawa. Jinin yana gudana ta cikin injin da ke cire ƙwayoyin sel. Sannan jinin yana dawowa ga mai bayarwa ta wata jijiya a daya hannun. (Mataki 2): Mai haƙuri yana karɓar magani don kashe ƙwayoyin halitta. Mai haƙuri na iya karɓar maganin radiation (ba a nuna ba). (Mataki na 3): Mai haƙuri yana karɓar ƙwayoyin sel ta hanyar catheter da aka sanya a cikin jijiyoyin jini a cikin kirji.

Taimakon tallafi

Ana ba da kulawa na tallafi don rage matsalolin da cutar ta haifar ko kuma maganinta. Kulawa mai tallafi na iya haɗawa da aikin ƙarin jini ko magani, kamar maganin rigakafi don yaƙi da kamuwa da cuta.

Ciwon da aka yi niyya

Targeted far shine maganin cutar kansa wanda ke amfani da kwayoyi ko wasu abubuwa don afkawa ƙwayoyin kansa ba tare da cutar ƙwayoyin halitta ba. Ana amfani da magunguna masu niyya wadanda ake kira tyrosine kinase inhibitors (TKIs) don magance myelodysplastic / myeloproliferative neoplasm, wanda ba za'a iya rarraba shi ba. TKI suna toshe enzyme, tyrosine kinase, wanda ke sa ƙwayoyin sel su zama ƙwayoyin jini (fashewa) fiye da abin da jiki ke buƙata. Imatinib mesylate (Gleevec) TKI ne wanda za'a iya amfani dashi. Sauran magungunan maganin da aka yi niyya ana nazarin su a cikin maganin JMML.

Duba Magunguna da Aka Amince dasu don Ciwon Myeloproliferative Neoplasms don ƙarin bayani.

Ana gwada sababbin nau'ikan magani a gwajin asibiti.

Ana samun bayani game da gwaji na asibiti daga gidan yanar gizon NCI.

Jiyya don myelodysplastic / myeloproliferative neoplasms na iya haifar da sakamako masu illa.

Don bayani game da illolin da cutar ta kansar ta haifar, duba shafin mu na Side Side.

Marasa lafiya na iya son yin tunani game da shiga cikin gwaji na asibiti.

Ga wasu marasa lafiya, shiga cikin gwaji na asibiti na iya zama mafi kyawun zaɓin magani. Gwajin gwaji wani bangare ne na aikin binciken cutar kansa. Ana yin gwaje-gwajen asibiti don gano ko sabbin maganin cutar daji suna da lafiya da tasiri ko kuma sun fi magani na yau da kullun.

Yawancin yau da kullun na yau da kullun don cutar kansa sun dogara ne akan gwajin asibiti na farko. Marasa lafiya da ke cikin gwaji na asibiti na iya karɓar daidaitaccen magani ko kuma su kasance cikin farkon waɗanda za su karɓi sabon magani.

Marasa lafiya da ke shiga cikin gwaji na asibiti suma suna taimakawa inganta hanyar da za a bi da kansar a nan gaba. Koda lokacin gwajin asibiti bai haifar da sababbin magunguna ba, sau da yawa sukan amsa mahimman tambayoyi kuma suna taimakawa ci gaba da bincike gaba.

Marasa lafiya na iya shiga gwajin asibiti kafin, lokacin, ko bayan fara maganin cutar kansa.

Wasu gwaji na asibiti kawai sun haɗa da marasa lafiya waɗanda ba su sami magani ba tukuna. Sauran gwaje-gwajen suna gwada jiyya ga marasa lafiya waɗanda cutar kansa ba ta samu sauki ba. Hakanan akwai gwaji na asibiti da ke gwada sabbin hanyoyin dakatar da cutar kansa daga sake dawowa (dawowa) ko rage tasirin maganin kansar.

Gwajin gwaji na gudana a sassa da yawa na ƙasar. Bayani game da gwajin asibiti wanda NCI ke tallafawa ana iya samun shi akan shafin binciken gwaji na NCI. Ana iya samun gwajin gwaji na asibiti wanda wasu kungiyoyi ke tallafawa akan gidan yanar gizon ClinicalTrials.gov.

Ana iya buƙatar gwaje-gwaje na gaba.

Za a iya maimaita wasu gwaje-gwajen da aka yi don gano cutar kansa ko don gano matakin cutar kansa. Za a maimaita wasu gwaje-gwaje don ganin yadda magani ke aiki. Shawarwari game da ci gaba, canji, ko dakatar da magani na iya dogara ne da sakamakon waɗannan gwaje-gwajen.

Wasu daga cikin gwaje-gwajen za a ci gaba da yi daga lokaci zuwa lokaci bayan an gama jiyya. Sakamakon waɗannan gwaje-gwajen na iya nuna idan yanayin ku ya canza ko kuma idan kansar ta sake dawowa (dawo). Wadannan gwaje-gwajen wasu lokuta ana kiran su gwaje-gwaje na gaba ko dubawa.

Zaɓuɓɓukan Jiyya don Myelodysplastic / Myeloproliferative Neoplasms

A Wannan Sashin

• Na kullum Myelomonocytic cutar sankarar bargo

• Ciwon yara Myelomonocytic Cutar sankarar bargo

• Atypical Chronic Myelogenous cutar sankarar bargo

• Myelodysplastic / Myeloproliferative Neoplasm, Ba za a iya rarraba shi ba

Don bayani game da jiyya da aka jera a ƙasa, duba sashin Kula da Zaɓin Jiyya.

Na kullum Myelomonocytic cutar sankarar bargo

Jiyya na cutar sankarar myelomonocytic na kullum (CMML) na iya haɗa da masu zuwa:

• Chemotherapy tare da ɗaya ko fiye wakilai.

• Dasawar dasa kara

• Gwajin gwaji na sabon magani.

Yi amfani da binciken bincikenmu na asibiti don nemo NCI na goyan bayan gwajin asibiti wanda ke karɓar marasa lafiya. Kuna iya bincika gwaji dangane da nau'in ciwon daji, shekarun mai haƙuri, da kuma inda ake yin gwajin. Ana samun cikakken bayani game da gwaji na asibiti.

Ciwon yara Myelomonocytic Cutar sankarar bargo

Kula da cutar sankarar bargo na yara (JMML) na iya haɗa da masu zuwa:

• Hade chemotherapy.

• Dasawar dasa kara

• 13-cis-retinoic acid magani.

• Gwajin gwaji na sabon magani, kamar maganin warkewa.

Yi amfani da binciken bincikenmu na asibiti don nemo NCI na goyan bayan gwajin asibiti wanda ke karɓar marasa lafiya. Kuna iya bincika gwaji dangane da nau'in ciwon daji, shekarun mai haƙuri, da kuma inda ake yin gwajin. Ana samun cikakken bayani game da gwaji na asibiti.

Atypical Chronic Myelogenous cutar sankarar bargo

Yin jiyya na cutar sankarar bargo mara ciwo (CML) na iya haɗawa da cutar sankara.

Yi amfani da binciken bincikenmu na asibiti don nemo NCI na goyan bayan gwajin asibiti wanda ke karɓar marasa lafiya. Kuna iya bincika gwaji dangane da nau'in ciwon daji, shekarun mai haƙuri, da kuma inda ake yin gwajin. Ana samun cikakken bayani game da gwaji na asibiti.

Myelodysplastic / Myeloproliferative Neoplasm, Ba za a iya rarraba shi ba

Saboda myelodysplastic / myeloproliferative neoplasm, wanda ba za a iya rarraba shi ba (MDS / MPN-UC) cuta ce wacce ba kasafai ake samunta ba, ba a san komai game da maganinta ba. Jiyya na iya haɗa da masu zuwa:

• Magungunan kulawa na tallafi don magance matsalolin da cutar ta haifar kamar kamuwa da cuta, zubar jini, da ƙarancin jini.

• Ci gaba da aka yi niyya (imatinib mesylate).

Yi amfani da binciken bincikenmu na asibiti don nemo NCI na goyan bayan gwajin asibiti wanda ke karɓar marasa lafiya. Kuna iya bincika gwaji dangane da nau'in ciwon daji, shekarun mai haƙuri, da kuma inda ake yin gwajin. Ana samun cikakken bayani game da gwaji na asibiti.

Don Moreara Koyo Game da Myelodysplastic / Myeloproliferative Neoplasms

Don ƙarin bayani daga Cibiyar Cancer ta cerasa game da myelodysplastic / myeloproliferative neoplasms, duba mai zuwa:

• Myeloproliferative Neoplasms Home Page

• Tattara Kwayoyin Halitta mai Yin jini

• Magunguna da Aka Amince da Myeloproliferative Neoplasms

• Magungunan Ciwon Cutar da Aka Yi niyya

Don cikakkun bayanai game da cutar kansa da sauran albarkatu daga Cibiyar Cancer ta Kasa, duba mai zuwa:

• Game da Ciwon daji

• Tsayawa

• Chemotherapy da ku: Tallafi ga Mutanen da ke Ciwon daji

• Radiation Far da Kai: Taimako ga Mutane Tare da Ciwon daji

• Yin fama da Ciwon daji

• Tambayoyi don Tambayar Doctor game da Ciwon daji

• Don Tsira da Kulawa