Types/myeloproliferative/patient/chronic-treatment-pdq

Kulawa da Ciwon Neoplasms na Myeloproliferative (®) -Shafin haƙuri

Janar Bayani Game da Cutar Ciwon Cutar Myeloproliferative Neoplasms

MAGANAN MAGANA

• Myeloproliferative neoplasms wani rukuni ne na cututtuka wanda ƙashin kashin yana sanya jajayen ƙwayoyin jini da yawa, farin ƙwayoyin jini, ko platelets.

• Akwai nau'ikan 6 na yau da kullun na yau da kullun.

• Ana amfani da gwaje-gwajen da ke bincikar jini da ƙashin ƙashi don bincikar cututtukan ƙwayoyin cuta na yau da kullun.

Myeloproliferative neoplasms wani rukuni ne na cututtuka wanda ƙashin kashin yana sanya jajayen ƙwayoyin jini da yawa, farin ƙwayoyin jini, ko platelets.

A yadda aka saba, ƙashin ƙasusuwa yana sa ƙwayoyin jini na jini (ƙwayoyin da ba su balaga ba) waɗanda suka zama ƙwararrun ƙwayoyin jini a kan lokaci.

Anatomy na kashi. Kashin ya kunshi karamin kashi, kashin baya, da kashin baya. Karamin kashi yana yin layin waje na ƙashi. Ana samun kashin Spongy galibi a ƙarshen ƙasusuwa kuma yana ɗauke da jajaja. Ana samun kasusuwan kasusuwa a tsakiyar mafi yawan kasusuwa kuma yana da jijiyoyi da yawa. Akwai kashin kashi biyu: ja da rawaya. Jan kashin jini ya ƙunshi ƙwayoyin jini wanda zai iya zama jajayen ƙwayoyin jini, fararen ƙwayoyin jini, ko platelets. An sanya kasusuwan rawaya mafi yawan mai.

Stemwayar ƙwayar ƙwayar jini na iya zama ƙwayar ƙwayar myeloid ko ƙwayar ƙwayar ƙwayar lymphoid. Kwayar kwayar lymphoid ta zama farin jini. Kwayar kara kuzari ta myeloid ta zama ɗayan nau'ikan nau'ikan ƙwayoyin jini uku masu girma:

• Jajayen jini wadanda suke daukar iskar oxygen da sauran abubuwa zuwa dukkan kyallen takarda.

• Farin jini wanda ke yakar kamuwa da cuta.

• Platelets wadanda suke samar da daskararren jini dan tsaida zubar jini.

Ci gaban kwayar jini. Kwayar sel ta jini tana wucewa ta matakai da yawa don zama jajayen jini, platelet, ko kuma farin jini.

A cikin neoplasms na myeloproliferative, yawancin kwayar halittar jini suna zama daya ko fiye da nau'in kwayoyin jini. Neoplasms yawanci yakanyi muni a hankali yayin da adadin ƙarin ƙwayoyin jini ke ƙaruwa.

Akwai nau'ikan 6 na yau da kullun na yau da kullun.

Nau'in myeloproliferative neoplasm ya dogara ne akan ko ana yin jan jini da yawa, farin ƙwayoyin jini, ko platelets. Wani lokaci jiki zai yi yawa fiye da nau'in kwayar jini, amma yawanci wani nau'in kwayar jini ya fi tasiri fiye da sauran. Neananan neoplasms na myeloproliferative sun haɗa da nau'ikan 6 masu zuwa:

• Cutar sankarar jini na yau da kullun.

• Polycythemia vera.

• Myelofibrosis na farko (wanda ake kira myelofibrosis na yau da kullun).

• Tsarin mahimmanci na thrombocythemia.

• Kullum cutar sankarar bargo

• Cutar sankarar bargo eosinophilic.

An bayyana waɗannan nau'ikan a ƙasa. Newayoyin cututtukan ƙwayoyin cuta na wani lokacin sukan zama cutar sankarar bargo, wanda a ciki ana yin ƙwayoyin jinin farin da yawa.

Ana amfani da gwaje-gwajen da ke bincikar jini da ƙashin ƙashi don bincikar cututtukan ƙwayoyin cuta na yau da kullun.

Za a iya amfani da waɗannan gwaje-gwajen da hanyoyin:

• Jarabawa ta jiki da tarihin lafiya: Jarabawa ta jiki don bincika alamomin lafiya gaba ɗaya, gami da bincika alamun cuta, kamar kumburi ko wani abu da kamar baƙon abu. Za a kuma ɗauki tarihin al'adun lafiyar marasa lafiya da cututtukan da suka gabata da magunguna.

• Cikakken ƙidayar jini (CBC) tare da banbanci: Hanyar da za'a zana samfurin jini kuma a bincika ta mai zuwa:

• Yawan jajayen kwayoyin jini da platelets.

• Adadi da nau'in farin jini.

• Adadin haemoglobin (furotin da ke ɗauke da iskar oxygen) a cikin ƙwayoyin jinin jini.

• Yankin samfurin jini ya kunshi jajayen ƙwayoyin jini.

Kammala lissafin jini (CBC). Ana tattara jini ta hanyar sanya allura a cikin jijiya da kuma barin jini ya kwarara cikin bututu. Ana aika samfurin jini zuwa dakin gwaje-gwaje kuma ana kidaya ƙwayoyin jinin jini, fararen ƙwayoyin jini, da kuma platelets. Ana amfani da CBC don gwadawa, gano asali, da kuma lura da yanayi daban-daban.

• Shafar jinin gefe: Hanya ce wacce ake bincika samfurin jini don masu zuwa:

• Shin ko akwai jajayen kwayoyin halittar jini kamar su hawaye.

• Adadi da nau'ikan fararen ƙwayoyin jini.

• Yawan platelets.

• Ko akwai ƙwayoyin rai.

• Nazarin ilimin sunadarai na jini: Hanya ce wacce ake bincikar samfurin jini don auna adadin wasu abubuwa da aka saki a cikin jini ta gabobi da kayan aiki a jiki. Adadin abu na yau da kullun (mafi girma ko ƙasa da al'ada) na iya zama alamar cuta.

• Burin kasusuwan kasusuwa da kuma biopsy: Cire kasusuwan kasusuwa, jini, da karamin guntun kashi ta hanyar sanya allura mara kyau a cikin kashin hanji ko kashin mama. Wani masanin ilimin ɗan adam ya kalli kasusuwan kasusuwa, jini, da ƙashi a ƙarƙashin microscope don neman ƙwayoyin cuta mara kyau.

Burin kasusuwa da biopsy. Bayan an lasafta wani karamin yanki na fata, ana saka allurar kasusuwa ta kashin a cikin kashin hancin mara lafiyar. Ana cire samfurorin jini, kashi, da kashin nama don bincike a karkashin wani madubin likita.

• Nazarin Cytogenetic: Gwajin dakin gwaje-gwaje wanda aka kirga chromosomes na kwayoyin halitta a cikin samfurin kasusuwan ƙashi ko jini kuma ana duba su don kowane canje-canje, kamar karye, ɓacewa, sake gyarawa, ko ƙarin ƙwayoyin cuta. Canje-canje a cikin wasu chromosomes na iya zama alamar cutar kansa. Ana amfani da nazarin Cytogenetic don taimakawa gano cutar kansa, shirya magani, ko gano yadda magani ke aiki.

• Gwajin maye gurbin kwayar halitta : Gwajin gwaje-gwaje da aka yi akan jijiyar kashi ko samfurin jini don bincika maye gurbi a kwayoyin JAK2, MPL, ko kwayoyin CALR. Kwayar halittar JAK2 sau da yawa ana samunta a cikin marasa lafiya da ke fama da cutar polycythemia vera, mahimmin thrombocythemia, ko myelofibrosis na farko. Ana samun maye gurbi na MPL ko CALR a cikin marasa lafiya tare da mahimman ƙwayoyin cuta ko kuma myelofibrosis na farko.

Kwancen Myelogenous Leukemia

Myelogenous leukemia wata cuta ce wadda ake yin fararen ƙwayoyin jini da yawa a cikin ɓarin ƙashi. Duba taƙaitaccen bayanin akan Ciwon Cutar sankarar jini na Myelogenous na yau da kullun don bayani game da ganewar asali, shiryawa, da magani.

Polycythemia Vera

MAGANAN MAGANA

• Polycythemia vera cuta ce wacce a ciki ake yin jan jini da yawa a cikin ɓarin ƙashi.

• Kwayar cutar polycythemia vera sun hada da ciwon kai da jin cikewar kasa da hakarkarin da ke gefen hagu.

• Ana amfani da gwaje-gwajen jini na musamman don bincikar cutar polycythemia vera.

Polycythemia vera cuta ce wacce a ciki ake yin jan jini da yawa a cikin ɓarin ƙashi.

A cikin polycythemia vera, jinin ya daskare da jan jini da yawa. Hakanan adadin farin jini da platelets na iya karuwa. Waɗannan ƙarin ƙwayoyin jinin na iya tattarawa a cikin saifa kuma su sa shi ya kumbura. Numberara yawan ƙwayoyin jinin jini, farin ƙwayoyin jini, ko platelets a cikin jini na iya haifar da matsalolin zub da jini da kuma sa daskarewa su zama cikin jijiyoyin jini. Wannan na iya kara haɗarin bugun jini ko bugun zuciya. A cikin marasa lafiyar da suka girmi shekaru 65 ko kuma suke da tarihin daskarewa na jini, haɗarin bugun jini ko bugun zuciya ya fi haka. Har ila yau, marasa lafiya suna da ƙarin haɗarin cutar sankarar myeloid mai tsanani ko myelofibrosis na farko.

Kwayar cutar polycythemia vera sun hada da ciwon kai da jin cikewar kasa da hakarkarin da ke gefen hagu.

Polycythemia vera galibi baya haifar da alamomi ko alamomin farko. Ana iya samun sa yayin gwajin jini na yau da kullun. Alamomi da alamu na iya faruwa yayin da adadin ƙwayoyin jini ke ƙaruwa. Sauran yanayi na iya haifar da alamu iri ɗaya. Duba tare da likitanka idan kuna da ɗayan masu zuwa:

• Jin nauyi ko cikawa ƙasa da haƙarƙarin gefen hagu.

• Ciwon kai.

• Gani biyu ko ganin duhu ko makaho waɗanda suke zuwa da tafi.

• Yin ƙaiƙayi a duk jiki, musamman bayan kasancewa cikin ruwan ɗumi ko ruwan zafi.

• Fushin fuska wanda yayi kama da jin ƙai ko kunar rana.

• Rashin ƙarfi.

• Dizziness.

• Rashin nauyi ba tare da wani dalili da aka sani ba.

Ana amfani da gwaje-gwajen jini na musamman don bincikar cutar polycythemia vera.

Baya ga cikakken ƙididdigar jini, burin kasusuwa da biopsy, da nazarin cytogenetic, ana amfani da gwajin kwayar cutar erythropoietin don gano vera polycythemia. A wannan gwajin, ana bincikar samfurin jini don matakin erythropoietin (wani sinadarin hormone da ke motsa sabbin ƙwayoyin jan jini da za a yi). A cikin polycythemia vera, matakin erythropoietin zai zama ƙasa da na al'ada saboda jiki baya buƙatar yin ƙarin jajayen ƙwayoyin jini.

Myelofibrosis na farko

MAGANAN MAGANA

• Primary myelofibrosis cuta ne wanda a cikin sa ƙwayoyin jini mara kyau da fibers suke haɗuwa a cikin ɓarin ƙashi.

• Kwayar cututtukan cututtukan myelofibrosis na farko sun hada da ciwo a kasan hakarkarinsa a bangaren hagu da kuma jin gajiya sosai.

• Wasu dalilai suna shafar hangen nesa (damar dawowa) da zaɓuɓɓukan magani don myelofibrosis na farko.

Primary myelofibrosis cuta ne wanda a cikin sa ƙwayoyin jini mara kyau da fibers suke haɗuwa a cikin ɓarin ƙashi.

Marashin kashin an yi shi ne da kyallen takarda wanda ke yin ƙwayoyin jini (jajayen ƙwayoyin jini, fararen ƙwayoyin jini, da platelets) da kuma yanar gizo na zaren da ke tallafawa ƙwayoyin halitta. A cikin myelofibrosis na farko (wanda kuma ake kira myelofibrosis na idiopathic na yau da kullun), adadi mai yawa na ƙwayoyin jini suna zama ƙwayoyin jini waɗanda ba su balaga yadda ya kamata (fashewa). Gidan yanar gizo na zaruruwa a cikin kashin kashin kuma ya zama mai kauri sosai (kamar kayan kyallen tabo) kuma yana jinkirta ikon halittar jini na yin kwayoyin jini. Wannan yana haifar da kwayoyin halittar da ke samar da jini suyi kadan da karancin kwayoyin jini. Don cike ƙananan ƙwayoyin ƙwayoyin jini da aka yi a cikin ƙashi, hanta da baƙin ciki sun fara yin ƙwayoyin jini.

Kwayar cututtukan cututtukan myelofibrosis na farko sun hada da ciwo a kasan hakarkarinsa a bangaren hagu da kuma jin gajiya sosai.

Myelofibrosis na farko ba ya haifar da alamun farko. Ana iya samun sa yayin gwajin jini na yau da kullun. Ana iya haifar da alamu da alamun cutar ta farkon myelofibrosis ko ta wasu yanayi. Duba tare da likitanka idan kuna da ɗayan masu zuwa:

• Jin zafi ko cika a ƙasa da haƙarƙarin a gefen hagu.

• Jin cikakken lokaci kafin cin abinci.

• Jin kasala sosai.

• Rashin numfashi.

• Aramar rauni ko zubar jini.

• Petechiae (lebur, ja, tabo mai kyau a karkashin fata wanda ke haifar da zubar jini).

• Zazzaɓi.

• Zafin zufa na dare.

• Rage nauyi.

Wasu dalilai suna shafar hangen nesa (damar dawowa) da zaɓuɓɓukan magani don myelofibrosis na farko.

Hangen nesa ya dogara da masu zuwa:

• Shekarun mara lafiya.

• Adadin ƙwayoyin jan jini da na farin jini.

• Yawan fashewa a cikin jini.

• Ko akwai wasu canje-canje a cikin chromosomes.

• Ko mai haƙuri yana da alamomi kamar zazzabi, dusar dusar dare, ko rage nauyi.

Tashin hankali mai mahimmanci

MAGANAN MAGANA

• Trombocythemia mai mahimmanci cuta ce wacce a ke yin platelet da yawa a cikin ɓarin ƙashi.

• Marasa lafiya tare da mahimmin maganin ƙwaƙwalwa na iya zama ba su da alamu ko alamu.

• Wasu dalilai suna shafar hangen nesa (damar dawowa) da zaɓuɓɓukan magani don mahimmancin thrombocythemia.

Trombocythemia mai mahimmanci cuta ce wacce a ke yin platelet da yawa a cikin ɓarin ƙashi.

Trombocythemia mai mahimmanci yana haifar da hauhawar mahaukaci a cikin adadin platelet da ake yi a cikin jini da ƙashin ƙashi.

Marasa lafiya tare da mahimmin maganin ƙwaƙwalwa na iya zama ba su da alamu ko alamu.

Maganin thrombocythemia sau da yawa baya haifar da alamun farko. Ana iya samun sa yayin gwajin jini na yau da kullun. Alamu da alamomin na iya haifar da mahimman ƙwayoyin cuta ko wasu yanayi. Duba tare da likitanka idan kuna da ɗayan masu zuwa:

• Ciwon kai.

• Ingonewa ko girgizawa a hannu ko ƙafa.

• Redness da dumi na hannu ko ƙafa.

• Gani ko matsalar rashin ji.

Farantun roba suna da danko. Lokacin da yawan platelet yayi yawa, zasu iya dunkulewa su zama abu mai wuya ga jini ya kwarara. Tsanani yana iya zama a cikin jijiyoyin jini kuma ana iya samun ƙaruwar zubar jini. Wadannan na iya haifar da manyan matsalolin lafiya kamar bugun jini ko bugun zuciya.

Wasu dalilai suna shafar hangen nesa (damar dawowa) da zaɓuɓɓukan magani don mahimmancin thrombocythemia.

Hanyar hangen nesa da zaɓuɓɓukan magani sun dogara da masu zuwa:

• Shekarun mara lafiya.

• Ko mai haƙuri yana da alamu ko alamomi ko wasu matsaloli masu alaƙa da mahimman ƙwayoyin cuta.

Cutar cutar sankarar bargo ta Neutrophilic

Tsarin kwayar cutar sankarau na yau da kullun cuta ce wacce yawancin kwayoyin kara jini ke zama nau'in farin jini wanda ake kira neutrophils. Neutrophils sune ƙwayoyin jini waɗanda ke yaƙi da cuta waɗanda ke kewaye da lalata matattun ƙwayoyin da baƙon abubuwa (kamar ƙwayoyin cuta). Saifa da hanta na iya kumbura saboda karin neutrophils. Cutar sankarar bargo na yau da kullun na iya kasancewa daidai ko kuma tana iya ci gaba cikin sauri zuwa cutar sankarar bargo mai tsanani.

Na kullum Eosinophilic cutar sankarar bargo

MAGANAN MAGANA

• Cutar sankarau ta eosinophilic na yau da kullun cuta ce wacce a ke yin farin jini da yawa (eosinophils) a cikin ɓarin ƙashi.

• Alamomi da alamomin cututtukan sankarau na yau da kullun sun hada da zazzabi da jin kasala sosai.

Cutar sankarau ta eosinophilic na yau da kullun cuta ce wacce a ke yin farin jini da yawa (eosinophils) a cikin ɓarin ƙashi.

Eosinophils sune fararen ƙwayoyin jini waɗanda ke amsawa ga abubuwan da ke haifar da haɗari (abubuwan da ke haifar da amsawar rashin lafiyan) kuma suna taimakawa yaƙi da cututtukan da wasu ƙwayoyin cuta ke haifar. A cikin cutar sankarar jini ta eosinophilic, akwai eosinophils da yawa a cikin jini, bargon kashi, da sauran kayan kyallen takarda. Cutar sankarar bargo eosinophilic na iya kasancewa daidai tsawon shekaru ko kuma yana iya ci gaba da sauri zuwa cutar sankarar bargo mai tsanani.

Alamomi da alamomin cututtukan sankarau na yau da kullun sun hada da zazzabi da jin kasala sosai.

Cutar sankarar jini ta eosinophilic na yau da kullun bazai haifar da alamun farko ba. Ana iya samun sa yayin gwajin jini na yau da kullun. Ana iya haifar da alamomi da cutar sankarar bargo ko wasu yanayi. Duba tare da likitanka idan kuna da ɗayan masu zuwa:

• Zazzaɓi.

• Jin kasala sosai.

• Tari.

• Busawa a ƙarƙashin fata a kusa da idanu da leɓɓuka, a maƙogwaro, ko a hannaye da ƙafa.

• Ciwon tsoka.

• Itching.

• Gudawa.

Matakai na Cutar Myeloproliferative Neoplasms

MAGANAN MAGANA

• Babu daidaitaccen tsarin tsarkewa don ƙwayoyin cuta na yau da kullun.

Babu daidaitaccen tsarin tsarkewa don ƙwayoyin cuta na yau da kullun.

Staging hanya ce da ake amfani da ita don gano yadda cutar kansa ta bazu. Babu daidaitaccen tsarin tsarkewa don ƙwayoyin cuta na yau da kullun. Jiyya ya dogara da nau'in ƙwayar cuta mai ƙyama wanda mara lafiya ke da shi. Yana da mahimmanci a san nau'in don shirya magani.

Bayanin Zaɓin Jiyya

MAGANAN MAGANA

• Akwai nau'ikan magani daban-daban ga marasa lafiya da keɓaɓɓen ƙwayoyin cuta.

• Ana amfani da nau'i goma na daidaitaccen magani:

• Jiran jira

• Ciwon ciki

• Apheresis na platelet

• Maganin dasa jini

• Chemotherapy

• Radiation far

• Sauran maganin magani

• Tiyata

• Biologic far

• Ciwon da aka yi niyya

• -Aramin magani mai ƙarfi tare da dasawar ƙwayar ƙwayar ƙwayar ƙwayar cuta

• Ana gwada sababbin nau'ikan magani a gwajin asibiti.

• Jiyya don ƙananan ƙwayoyin cuta na ƙwayoyin cuta na iya haifar da sakamako masu illa.

• Marasa lafiya na iya son yin tunani game da shiga cikin gwaji na asibiti.

• Marasa lafiya na iya shiga gwajin asibiti kafin, lokacin, ko bayan fara maganin cutar kansa.

• Ana iya buƙatar gwaje-gwaje na gaba.

Akwai nau'ikan magani daban-daban ga marasa lafiya da keɓaɓɓen ƙwayoyin cuta.

Akwai nau'ikan jiyya iri daban-daban ga marasa lafiya da ke fama da cutar neoplasms. Wasu jiyya suna daidaito (magani da ake amfani dashi yanzu), kuma wasu ana gwada su a gwajin asibiti. Gwajin gwajin magani shine binciken bincike wanda ake nufi don taimakawa inganta ingantattun jiyya na yanzu ko samun bayanai akan sabbin jiyya. Lokacin da gwaji na asibiti ya nuna cewa sabon magani ya fi magani na yau da kullun, sabon magani na iya zama daidaitaccen magani. Marasa lafiya na iya son yin tunani game da shiga cikin gwaji na asibiti. Wasu gwaji na asibiti ana buɗe su ne kawai ga marasa lafiyar da basu fara magani ba.

Ana amfani da nau'i goma na daidaitaccen magani:

Jiran jira

Tsayawa a hankali yana lura da yanayin mai haƙuri ba tare da ba da wani magani ba har sai alamu ko alamu sun bayyana ko canzawa.

Ciwon ciki

Phlebotomy hanya ce da ake karbar jini daga jijiya. Ana iya ɗaukar samfurin jini don gwaji kamar CBC ko sunadarai na jini. Wani lokaci ana amfani da phlebotomy azaman magani kuma ana ɗauke jini daga jiki don cire ƙarin jajayen ƙwayoyin jini. Ana amfani da Phlebotomy ta wannan hanyar don magance wasu cututtukan neoplasms na myeloproliferative.

Apheresis na platelet

Platelet apheresis magani ne wanda yake amfani da wata na'ura ta musamman don cire platelets daga cikin jini. Ana karɓar jini daga majiyyacin kuma a saka ta cikin mai raba tantanin jini inda ake cire platelets. Sauran jinin sai a mayar da su cikin jinin mara lafiyar.

Maganin dasa jini

Yin karin jini (ƙarin jini) hanya ce ta ba da jajayen jini, fararen ƙwayoyin jini, ko platelets don maye gurbin ƙwayoyin jinin da cuta ko kuma maganin kansa ya lalata.

Chemotherapy

Chemotherapy magani ne na cutar kansa wanda ke amfani da magunguna don dakatar da haɓakar ƙwayoyin kansa, ko dai ta hanyar kashe ƙwayoyin ko ta hana su rarraba. Lokacin da ake shan chemotherapy ta baki ko allura a cikin jijiya ko tsoka, magungunan suna shiga cikin jini kuma zasu iya kaiwa ga kwayoyin cutar kansa a cikin jiki duka (systemotherapy chemotherapy). Lokacin da aka sanya chemotherapy kai tsaye zuwa cikin ruwa mai ruɓaɓɓen ciki, gaɓoɓi, ko rami na jiki kamar ciki, magungunan yawanci suna shafar ƙwayoyin kansa ne a waɗancan yankuna. Hanyar da ake ba da cutar sankara ta dogara da nau'in da matakin cutar kansa.

Duba Magunguna da Aka Amince dasu don Ciwon Myeloproliferative Neoplasms don ƙarin bayani.

Radiation far

Radiation therapy magani ne na cutar kansa wanda yake amfani da hasken rana mai ƙarfi ko wasu nau'ikan radiation don kashe ƙwayoyin kansa ko hana su girma. Magungunan radiation na waje yana amfani da wata na'ura a wajen jiki don aika jujjuyawar zuwa jikin jiki da cutar kansa.

Ana amfani da magungunan ƙwayar cuta ta waje don magance ƙananan ƙwayoyin cuta, kuma yawanci ana jagorantar sifa.

Sauran maganin magani

Prednisone da danazol su ne magunguna waɗanda za a iya amfani da su don magance cutar ƙarancin jini a cikin marasa lafiya da ƙananan myelofibrosis.

Ana amfani da maganin Anagrelide don rage haɗarin daskarewar jini ga marasa lafiya waɗanda ke da platelet da yawa a cikin jinin su. Hakanan za'a iya amfani da aspirin mai ƙarancin ƙarfi don rage haɗarin daskarewar jini.

Thalidomide, lenalidomide, da pomalidomide su ne magungunan da ke hana jijiyoyin jini girma zuwa sassan ƙwayoyin tumo.

Duba Magunguna da Aka Amince dasu don Ciwon Myeloproliferative Neoplasms don ƙarin bayani.

Tiyata

Splenectomy (tiyata don cire saifa) ana iya yi idan an faɗaɗa saifa.

Biologic far

Magungunan ilimin halittu magani ne wanda ke amfani da garkuwar jikin mara lafiya don yaƙar kansa ko wasu cututtuka. Abubuwan da jiki ya yi ko aka yi a dakin gwaje-gwaje ana amfani da su don haɓaka, kai tsaye, ko dawo da kariya ta jiki daga cuta. Wannan nau'in magani ana kiransa biotherapy ko immunotherapy. Interferon alfa da pegylated interferon alpha su ne jami'o'in ilimin kimiyyar da ake amfani dasu don magance wasu cututtukan ƙwayoyin cuta na yau da kullun.

Abubuwan haɓaka Erythropoietic suma wakilai ne na ilimin halittu. Ana amfani dasu don motsa kumburin ƙashi don yin jajayen ƙwayoyin jini.

Ciwon da aka yi niyya

Targeted therapy wani nau'in magani ne wanda yake amfani da magunguna ko wasu abubuwa don ganowa da afkawa takamaiman ƙwayoyin cutar kansa ba tare da cutar ƙwayoyin halitta ba. Tyrosine kinase masu hanawa sune magunguna masu niyya waɗanda ke toshe siginonin da ake buƙata don ciwace-ciwacen su girma.

Ruxolitinib shine mai hana cin hanci da rashawa tyrosine kinase da ake amfani dashi don magance polycythemia vera da wasu nau'ikan myelofibrosis.

Duba Magunguna da Aka Amince dasu don Ciwon Myeloproliferative Neoplasms don ƙarin bayani.

Sauran nau'ikan hanyoyin kwantar da hankalin da ake niyya ana nazarin su a gwajin asibiti.

-Aramin magani mai ƙarfi tare da dasawar ƙwayar ƙwayar ƙwayar ƙwayar cuta

An bayar da babban allurai don kashe ƙwayoyin kansa. Kwayoyin lafiya, gami da ƙwayoyin halitta masu jini, suma ana lalata su ta hanyar maganin kansa. Dasawar sel shine magani don maye gurbin kwayoyin halitta. Ana cire ƙwayoyin sari (ƙwayoyin jinin da basu balaga ba) daga cikin jinin ko ƙashin ƙashin mara lafiya ko mai bayarwa kuma ana daskarar dasu ana adana su. Bayan mai haƙuri ya gama shan magani, sai a narke ƙwayoyin ƙwayoyin da aka adana kuma a mayar da su ga mai haƙuri ta hanyar jiko. Waɗannan ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin na ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin na ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin na ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin na ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin magungunan za a ɗibar

Dasawar dasa kara (Mataki na 1): Ana ɗaukar jini daga jijiya a hannun mai bayarwa. Mai haƙuri ko wani mutum na iya zama mai ba da gudummawa. Jinin yana gudana ta cikin injin da ke cire ƙwayoyin sel. Sannan jinin yana dawowa ga mai bayarwa ta wata jijiya a daya hannun. (Mataki 2): Mai haƙuri yana karɓar magani don kashe ƙwayoyin halitta. Mai haƙuri na iya karɓar maganin radiation (ba a nuna ba). (Mataki na 3): Mai haƙuri yana karɓar ƙwayoyin sel ta hanyar catheter da aka sanya a cikin jijiyoyin jini a cikin kirji.

Ana gwada sababbin nau'ikan magani a gwajin asibiti.

Ana samun bayani game da gwaji na asibiti daga gidan yanar gizon NCI.

Jiyya don ƙananan ƙwayoyin cuta na ƙwayoyin cuta na iya haifar da sakamako masu illa.

Don bayani game da illolin da cutar ta kansar ta haifar, duba shafin mu na Side Side.

Marasa lafiya na iya son yin tunani game da shiga cikin gwaji na asibiti.

Ga wasu marasa lafiya, shiga cikin gwaji na asibiti na iya zama mafi kyawun zaɓin magani. Gwajin gwaji wani bangare ne na aikin binciken cutar kansa. Ana yin gwaje-gwajen asibiti don gano ko sabbin maganin cutar daji suna da lafiya da tasiri ko kuma sun fi magani na yau da kullun.

Yawancin yau da kullun na yau da kullun don cutar kansa sun dogara ne akan gwajin asibiti na farko. Marasa lafiya da ke cikin gwaji na asibiti na iya karɓar daidaitaccen magani ko kuma su kasance cikin farkon waɗanda za su karɓi sabon magani.

Marasa lafiya da ke shiga cikin gwaji na asibiti suma suna taimakawa inganta hanyar da za a bi da kansar a nan gaba. Koda lokacin gwajin asibiti bai haifar da sababbin magunguna ba, sau da yawa sukan amsa mahimman tambayoyi kuma suna taimakawa ci gaba da bincike gaba.

Marasa lafiya na iya shiga gwajin asibiti kafin, lokacin, ko bayan fara maganin cutar kansa.

Wasu gwaji na asibiti kawai sun haɗa da marasa lafiya waɗanda ba su sami magani ba tukuna. Sauran gwaje-gwajen suna gwada jiyya ga marasa lafiya waɗanda cutar kansa ba ta samu sauki ba. Hakanan akwai gwaji na asibiti da ke gwada sabbin hanyoyin dakatar da cutar kansa daga sake dawowa (dawowa) ko rage tasirin maganin kansar.

Gwajin gwaji na gudana a sassa da yawa na ƙasar. Bayani game da gwajin asibiti wanda NCI ke tallafawa ana iya samun shi akan shafin binciken gwaji na NCI. Ana iya samun gwajin gwaji na asibiti wanda wasu kungiyoyi ke tallafawa akan gidan yanar gizon ClinicalTrials.gov.

Ana iya buƙatar gwaje-gwaje na gaba.

Za a iya maimaita wasu gwaje-gwajen da aka yi don gano cutar kansa ko don gano matakin cutar kansa. Za a maimaita wasu gwaje-gwaje don ganin yadda magani ke aiki. Shawarwari game da ci gaba, canji, ko dakatar da magani na iya dogara ne da sakamakon waɗannan gwaje-gwajen.

Wasu daga cikin gwaje-gwajen za a ci gaba da yi daga lokaci zuwa lokaci bayan an gama jiyya. Sakamakon waɗannan gwaje-gwajen na iya nuna idan yanayin ku ya canza ko kuma idan kansar ta sake dawowa (dawo). Wadannan gwaje-gwajen wasu lokuta ana kiran su gwaje-gwaje na gaba ko dubawa.

Jiyya na Ciwon Myeloproliferative Neoplasms

A Wannan Sashin

• Kwancen Myelogenous Leukemia

• Polycythemia Vera

• Myelofibrosis na farko

• Tashin hankali mai mahimmanci

• Cutar cutar sankarar bargo ta Neutrophilic

• Na kullum Eosinophilic cutar sankarar bargo

Don bayani game da jiyya da aka jera a ƙasa, duba sashin Kula da Zaɓin Jiyya.

Kwancen Myelogenous Leukemia

Dubi taƙaitaccen bayanin game da Magungunan cutar sankarar jini na Myelogenous don ƙarin bayani.

Polycythemia Vera

Dalilin magani ga polycythemia vera shine rage adadin karin kwayoyin jini. Jiyya na polycythemia vera na iya haɗa da masu zuwa:

• Ciwon ciki.

• Chemotherapy tare da ko ba tare da phlebotomy ba. Idan chemotherapy bai yi aiki ba, ana iya ba da maganin warkewa (ruxolitinib).

• Magungunan ilimin biologic ta amfani da interferon alfa ko pegylated interferon alpha.

• Asfirin mai ƙarancin ƙarfi.

Yi amfani da binciken bincikenmu na asibiti don nemo NCI na goyan bayan gwajin asibiti wanda ke karɓar marasa lafiya. Kuna iya bincika gwaji dangane da nau'in ciwon daji, shekarun mai haƙuri, da kuma inda ake yin gwajin. Ana samun cikakken bayani game da gwaji na asibiti.

Myelofibrosis na farko

Jiyya na myelofibrosis na farko a cikin marasa lafiya ba tare da alamu ko alamomi yawanci ana jira ba jira.

Marasa lafiya tare da myelofibrosis na farko na iya samun alamu ko alamun rashin jini. Anemia yawanci ana bi da shi tare da ƙarin jinin jini don sauƙaƙe alamomin da inganta rayuwar. Bugu da kari, ana iya maganin rashin jini tare da:

• Abubuwa masu girma na Erythropoietic.

• Prednisone

• Danazol.

• Thalidomide, lenalidomide, ko pomalidomide, tare da ko ba tare da prednisone ba.

Jiyya na myelofibrosis na farko a cikin marasa lafiya tare da wasu alamu ko alamomi na iya haɗa da masu zuwa:

• Neman da aka yi niyya tare da ruxolitinib.

• Chemotherapy.

• Donor kara cell dashi.

• Thalidomide, lenalidomide, ko pomalidomide.

• Splenectomy.

• Radiation na warkewa zuwa baƙin ciki, ƙwayoyin lymph, ko wasu yankuna a waje da ƙashin ƙashi inda ƙwayoyin jini ke kafa.

• Magungunan ilimin biologic ta amfani da interferon alfa ko abubuwan ci gaban erythropoietic.

• Gwajin gwaji na sauran magungunan maganin da aka yi niyya.

Yi amfani da binciken bincikenmu na asibiti don nemo NCI na goyan bayan gwajin asibiti wanda ke karɓar marasa lafiya. Kuna iya bincika gwaji dangane da nau'in ciwon daji, shekarun mai haƙuri, da kuma inda ake yin gwajin. Ana samun cikakken bayani game da gwaji na asibiti.

Tashin hankali mai mahimmanci

Jiyya mai mahimmanci thrombocythemia a cikin marasa lafiya ƙarancin shekaru 60 waɗanda ba su da alamu ko alamomi kuma ƙididdigar karɓaɓɓen ƙarancin jini yawanci jiran kallo ne. Jiyya na wasu marasa lafiya na iya haɗa da masu zuwa:

• Chemotherapy.

• Maganin Anagrelide.

• Magungunan ilimin biologic ta amfani da interferon alfa ko pegylated interferon alpha.

• Apheresis na platelet.

• Gwajin gwaji na sabon magani.

Yi amfani da binciken bincikenmu na asibiti don nemo NCI na goyan bayan gwajin asibiti wanda ke karɓar marasa lafiya. Kuna iya bincika gwaji dangane da nau'in ciwon daji, shekarun mai haƙuri, da kuma inda ake yin gwajin. Ana samun cikakken bayani game da gwaji na asibiti.

Cutar cutar sankarar bargo ta Neutrophilic

Jiyya na cutar sankarar bargo mai narkewa na iya haɗawa da masu zuwa:

• Don bada kasusuwa

• Chemotherapy.

• Biologic far ta amfani da interferon alfa.

• Gwajin gwaji na sabon magani.

Yi amfani da binciken bincikenmu na asibiti don nemo NCI na goyan bayan gwajin asibiti wanda ke karɓar marasa lafiya. Kuna iya bincika gwaji dangane da nau'in ciwon daji, shekarun mai haƙuri, da kuma inda ake yin gwajin. Ana samun cikakken bayani game da gwaji na asibiti.

Na kullum Eosinophilic cutar sankarar bargo

Jiyya na cutar sankarar bargo eosinophilic na iya haɗawa da masu zuwa:

• Sanya kashi

• Biologic far ta amfani da interferon alfa.

• Gwajin gwaji na sabon magani.

Yi amfani da binciken bincikenmu na asibiti don nemo NCI na goyan bayan gwajin asibiti wanda ke karɓar marasa lafiya. Kuna iya bincika gwaji dangane da nau'in ciwon daji, shekarun mai haƙuri, da kuma inda ake yin gwajin. Ana samun cikakken bayani game da gwaji na asibiti.

Don Moreara Koyo Game da Ciwon Myeloproliferative Neoplasms

Don ƙarin bayani daga Cibiyar Ciwon cerwayar Ciwon aboutasa game da ƙwaƙƙwaƙƙwan ƙwayoyin cuta, duba masu zuwa:

• Myeloproliferative Neoplasms Home Page

• Magunguna da Aka Amince da Myeloproliferative Neoplasms

• Immunotherapy don Kula da Ciwon daji

• Tattara Kwayoyin Halitta mai Yin jini

• Magungunan Ciwon Cutar da Aka Yi niyya

Don cikakkun bayanai game da cutar kansa da sauran albarkatu daga Cibiyar Cancer ta Kasa, duba mai zuwa:

• Game da Ciwon daji

• Tsayawa

• Chemotherapy da ku: Tallafi ga Mutanen da ke Ciwon daji

• Radiation Far da Kai: Taimako ga Mutane Tare da Ciwon daji

• Yin fama da Ciwon daji

• Tambayoyi don Tambayar Doctor game da Ciwon daji

• Don Tsira da Kulawa