Nau'o'in / cutar sankarar bargo / haƙuri / manya-aml-treatment-pdq

Adult Muteloid Ciwon Cutar sankarar jini na Adult (?) - Sigar haƙuri

Janar Bayani Game da Ciwon Matsalar Cutar Myeloid mai Ciwo

MAGANAN MAGANA

• Adult myeloid leukemia (AML) wani nau'in ciwon daji ne wanda ƙashin kashin baya ke haifar da myeloblasts mara kyau (wani nau'in ƙwayar ƙwayar farin jini), jajayen ƙwayoyin jini, ko platelets.

• Cutar sankarar bargo na iya shafar jajayen ƙwayoyin jini, fararen ƙwayoyin jini, da kuma platelets.

• Akwai nau'ikan nau'ikan AML.

• Shan sigari, magani na chemotherapy da ya gabata, da kuma kamuwa da radiation na iya shafar haɗarin AML mai girma.

• Alamomi da alamomin girma na AML sun hada da zazzabi, jin kasala, da saurin kunci ko zubar jini.

• Ana amfani da gwaje-gwajen da ke bincikar jini da ƙashin ƙashi don ganowa (samo) da kuma tantance manya AML.

• Wasu dalilai suna tasiri hangen nesa (damar dawowa) da zaɓuɓɓukan magani.

Adult myeloid leukemia (AML) wani nau'in ciwon daji ne wanda ƙashin kashin baya ke haifar da myeloblasts mara kyau (wani nau'in ƙwayar ƙwayar farin jini), jajayen ƙwayoyin jini, ko platelets.

Ciwon ƙwayar cutar sankarar myeloid na tsofaffi (AML) ciwon daji ne na jini da ƙashi. Irin wannan ciwon daji yakan zama da sauri idan ba a magance shi ba. Wannan shine nau'in cutar sankarar bargo mafi girma ga manya. AML kuma ana kiranta da cutar sankarar myelogenous mukelchi, mukeloblastic leukemia, m granulocytic leukemia, da kuma m nonlymphocytic leukemia.

Anatomy na kashi. Kashin ya kunshi karamin kashi, kashin baya, da kashin baya. Karamin kashi yana yin layin waje na ƙashi. Ana samun kashin Spongy galibi a ƙarshen ƙasusuwa kuma yana ɗauke da jajaja. Ana samun kasusuwan kasusuwa a tsakiyar mafi yawan kasusuwa kuma yana da jijiyoyi da yawa. Akwai kashin kashi biyu: ja da rawaya. Jan kashin jini ya ƙunshi ƙwayoyin jini wanda zai iya zama jajayen ƙwayoyin jini, fararen ƙwayoyin jini, ko platelets. An sanya kasusuwan rawaya mafi yawan mai.

Cutar sankarar bargo na iya shafar jajayen ƙwayoyin jini, fararen ƙwayoyin jini, da kuma platelets.

A yadda aka saba, ƙashin ƙasusuwa yana sa ƙwayoyin jini na jini (ƙwayoyin da ba su balaga ba) waɗanda suka zama ƙwararrun ƙwayoyin jini a kan lokaci. Stemwayar ƙwayar ƙwayar jini na iya zama ƙwayar ƙwayar myeloid ko ƙwayar ƙwayar ƙwayar lymphoid. Kwayar kwayar lymphoid ta zama farin jini.

Kwayar kara kuzari ta myeloid ta zama ɗayan nau'ikan nau'ikan ƙwayoyin jini uku masu girma:

• Jajayen jini wadanda suke daukar iskar oxygen da sauran abubuwa zuwa dukkan kyallen takarda.

• Farin jini wanda ke yakar kamuwa da cuta.

• Platelets wadanda suke samar da daskararren jini dan tsaida zubar jini.

Ci gaban kwayar jini. Kwayar sel ta jini tana wucewa ta matakai da yawa don zama jajayen jini, platelet, ko kuma farin jini.

A cikin AML, ƙwayoyin ƙwayoyin myeloid yawanci suna zama nau'in kwayar jinin fari wanda bai balaga ba wanda ake kira myeloblasts (ko fashewar myeloid). Myeloblasts a cikin AML mahaukaci ne kuma basu zama lafiyayyun ƙwayoyin jini ba. Wani lokaci a cikin AML, ƙwayoyin sel masu yawa da yawa suna zama jan jinin jini ko platelets. Waɗannan ƙananan ƙwayoyin jinin farin, jan jini, ko platelets ana kuma kiran su ƙwayoyin cutar sankarar bargo ko fashewa. Kwayoyin cutar sankarar bargo na iya haɗuwa a cikin ɓarin kasusuwa da jini don haka akwai ƙarancin wuri don lafiyayyen ƙwayoyin farin jini, jajayen ƙwayoyin jini, da platelets. Lokacin da wannan ya faru, kamuwa da cuta, ƙarancin jini, ko saurin zubar jini na iya faruwa. Kwayoyin cutar sankarar bargo na iya yadawa a wajen jini zuwa sauran sassan jiki, gami da tsarin jijiyoyin tsakiya (kwakwalwa da lakar kashin baya), fata, da gumis.

Wannan taƙaitaccen bayani game da AML ne mai girma. Duba takaitattun masu zuwa don bayani game da wasu nau'ikan cutar sankarar bargo:

• Yaran Ciwon Cutar Myeloid Mai Ciwo / Sauran Maganin Cutar Myeloid

• Magungunan cutar sankarar bargo na zamani

• Kulawa da Ciwon Cutar sankarar bargo na manya

• Kulawa da Ciwon Cutar sankarar bargo yara

• Magungunan cutar sankarar bargo na yau da kullun

• Jiyya Kwayar Cutar sankarar bargo

Akwai nau'ikan nau'ikan AML.

Yawancin ƙananan nau'ikan AML suna dogara ne akan yadda balagaggun ƙwayoyin kansar suke a lokacin bincike da kuma yadda suka bambanta da ƙwayoyin al'ada.

Promananan cutar sankarar bargo (APL) wani nau'in nau'in AML ne wanda ke faruwa yayin da sassan kwayoyin halitta biyu suka manne. APL yawanci yakan faru ne a cikin manya. Alamomin APL na iya haɗawa da zubar jini da kuma daskarewar jini.

Shan sigari, magani na chemotherapy da ya gabata, da kuma kamuwa da radiation na iya shafar haɗarin AML mai girma.

Duk wani abu da zai kara maka hadarin kamuwa da cuta to ana kiran sa mai hadari. Samun haɗari ba ya nufin cewa za ku kamu da cutar kansa; ba tare da haɗarin abubuwan haɗari ba yana nufin cewa ba zaku sami cutar kansa ba. Yi magana da likitanka idan kuna tsammanin kuna iya fuskantar haɗari. Abubuwan haɗarin haɗari na AML sun haɗa da masu zuwa:

• Kasancewa namiji.

• Shan taba, musamman bayan shekaru 60.

• Bayan samun magani tare da chemotherapy ko radiation a baya.

• Bayan an sha maganin cutar sankarar bargo na yara (ALL) a da.

• Kasancewa da siradi daga bam din atom ko kuma sinadarin benzene.

• Samun tarihin rikicewar jini kamar su myelodysplastic syndrome.

Alamomi da alamomin girma na AML sun hada da zazzabi, jin kasala, da saurin kunci ko zubar jini.

Alamomin farko da alamomin AML na iya zama kamar waɗanda mura da wasu cututtukan gama gari ke haifarwa. Duba tare da likitanka idan kuna da ɗayan masu zuwa:

• Zazzaɓi.

• Rashin numfashi.

• Aramar rauni ko zubar jini.

• Petechiae (lebur, tabo daidai a karkashin fata sanadiyyar zubar jini).

• Rashin rauni ko jin kasala.

• Rage nauyi ko rashin cin abinci.

Ana amfani da gwaje-gwajen da ke bincikar jini da ƙashin ƙashi don ganowa (samo) da kuma tantance manya AML.

Za a iya amfani da waɗannan gwaje-gwajen da hanyoyin:

• Jarabawa ta jiki da tarihi: Jarabawa ce ta jiki don bincika alamomin lafiya gaba ɗaya, gami da bincika alamun cuta, kamar kumburi ko wani abu da kamar baƙon abu. Za a kuma ɗauki tarihin al'adun lafiyar marasa lafiya da cututtukan da suka gabata da magunguna.

• Cikakken ƙidayar jini (CBC): Hanyar da za'a zana samfurin jini kuma a bincika ta mai zuwa:

• Adadin jajayen ƙwayoyin jini, fararen ƙwayoyin jini, da platelets.

• Adadin haemoglobin (furotin da ke ɗauke da iskar oxygen) a cikin ƙwayoyin jinin jini.

• Yankin samfurin ya kunshi jajayen ƙwayoyin jini.

Kammala lissafin jini (CBC). Ana tattara jini ta hanyar sanya allura a cikin jijiya da kuma barin jini ya kwarara cikin bututu. Ana aika samfurin jini zuwa dakin gwaje-gwaje kuma ana kidaya ƙwayoyin jinin jini, fararen ƙwayoyin jini, da kuma platelets. Ana amfani da CBC don gwadawa, gano asali, da kuma lura da yanayi daban-daban.

• Shafar jinin gefe: Hanya ce wacce ake bincika samfurin jini don ƙwayoyin fashewa, lamba da nau'ikan fararen ƙwayoyin jini, da yawan platelets, da canje-canje a cikin surar ƙwayoyin jini.

• Burin kasusuwan kasusuwa da kuma biopsy: Cire kasusuwan kasusuwa, jini, da karamin guntun kashi ta hanyar sanya allura mara kyau a cikin kashin hanji ko kashin mama. Wani masanin ilimin ɗan adam ya kalli ɓarkewar jini, jini, da ƙashi a ƙarƙashin madubin likita don neman alamun cutar kansa.

Burin kasusuwa da biopsy. Bayan an lasafta wani karamin yanki na fata, ana saka allurar kasusuwa ta kashin a cikin kashin hancin mara lafiyar. Ana cire samfurorin jini, kashi, da kashin nama don bincike a karkashin wani madubin likita.

• Nazarin Cytogenetic: Gwajin dakin gwaje-gwaje wanda aka kirga chromosomes na kwayoyi a cikin samfurin jini ko jiji da kashi don bincika kowane canje-canje, kamar karye, ɓacewa, sake gyarawa, ko ƙarin ƙwanƙwanni. Canje-canje a cikin wasu chromosomes na iya zama alamar cutar kansa. Ana amfani da nazarin Cytogenetic don taimakawa gano cutar kansa, shirya magani, ko gano yadda magani ke aiki. Sauran gwaje-gwaje, kamar haske a cikin yanayin haɗuwa (FISH), ƙila za a iya yin su don neman wasu canje-canje a cikin chromosomes.

• Immunophenotyping: Gwajin dakin gwaje-gwaje da ke amfani da kwayoyin cuta don gano kwayoyin cutar kansar dangane da nau'ikan antigens ko alamomi a saman sel. Ana amfani da wannan gwajin don taimakawa wajen gano takamaiman nau'ikan cutar sankarar bargo. Misali, binciken kimiyyar sankara na iya gwada kwayoyin halitta a cikin samfurin nama ta amfani da sinadarai (dyes) don neman wasu canje-canje a cikin samfurin. Wani sinadari na iya haifar da canjin launi a wani nau'in kwayar cutar sankarar jini amma ba a cikin wani nau'in kwayar cutar sankarar jini ba.

• Reverse transcription-polymerase sarkar dauki gwajin (RT-PCR): Gwajin gwaje-gwaje wanda aka auna yawan kwayar halittar da ake kira mRNA da aka kera ta wata kwayar halitta. Ana amfani da enzyme da ake kira transcriptase mai jujjuya don juya takamaiman yanki na RNA zuwa madaidaicin yanki na DNA, wanda za'a iya faɗaɗa shi (wanda aka yi shi da adadi mai yawa) ta wani enzyme mai suna DNA polymerase. Copiesididdigar DNA ɗin da aka faɗaɗa sun taimaka gaya ko ana yin takamaiman mRNA ta hanyar kwayar halitta. Ana iya amfani da RT-PCR don bincika kunna wasu ƙwayoyin halitta waɗanda na iya nuna kasancewar ƙwayoyin kansa. Ana iya amfani da wannan gwajin don neman wasu canje-canje a cikin kwayar halitta ko chromosome, wanda na iya taimakawa wajen gano cutar kansa. Ana amfani da wannan gwajin don tantance wasu nau'ikan AML gami da cutar sankarar bargo mai yaduwa (APL).

Wasu dalilai suna tasiri hangen nesa (damar dawowa) da zaɓuɓɓukan magani.

Hangen nesa (damar dawowa) da zaɓuɓɓukan magani sun dogara da:

• Shekarun mara lafiya.

• Karamin nau'in AML.

• Ko mai haƙuri ya karɓi chemotherapy a baya don magance cutar kansa daban.

• Ko akwai tarihin rikicewar jini kamar su myelodysplastic syndrome.

• Ko ciwon daji ya bazu zuwa tsarin juyayi na tsakiya.

• Ko an magance cutar daji kafin ko ta sake dawowa (dawo).

Yana da mahimmanci a kula da cutar sankarar bargo nan take.

Matakai na Ciwon Cutar Myeloid Mai Girma

MAGANAN MAGANA

• Da zarar an gano babban cutar sankarar myeloid (AML), ana yin gwaji don gano ko cutar kansa ta bazu zuwa wasu sassan jiki.

• Babu daidaitaccen tsarin tsarkewa don girma AML.

Da zarar an gano babban cutar sankarar myeloid (AML), ana yin gwaji don gano ko cutar kansa ta bazu zuwa wasu sassan jiki.

Yawancin lokaci ko yaduwar ciwon daji yawanci ana bayyana shi a matsayin matakai. A cikin babban cutar sankarar myeloid (AML), ƙaramin nau'in AML da kuma ko cutar sankarar jini ta bazu a wajen jini da ƙashin ƙashi ana amfani da su maimakon matakin don shirya magani. Ana iya amfani da gwaje-gwaje da hanyoyin da ke tafe don sanin ko cutar sankarar jini ta bazu:

• Lumbar puncture: Hanya ce da ake amfani da ita don tattara samfurin ruwan ciki (CSF) daga sashin kashin baya. Ana yin wannan ta sanya allura tsakanin ƙasusuwa biyu a cikin kashin baya da kuma cikin CSF a kewayen ƙashin baya da cire samfurin ruwan. An bincika samfurin CSF a ƙarƙashin microscope don alamun da ke nuna cewa cutar sankarar bargo ta bazu zuwa kwakwalwa da laka. Wannan hanyar ana kiranta LP ko taɓar kashin baya.

Lumbar huda Mai haƙuri yana kwance a cikin lankwasawa akan tebur. Bayan an kidaya wani karamin yanki a kasan baya, sai a saka allura ta kashin baya (dogon, siririn sirara) a cikin sashin kasan kashin kashin baya don cire ruwan ciki na kwakwalwa (CSF, wanda aka nuna a shudi). Ana iya aika ruwan zuwa dakin gwaje-gwaje don gwaji.

• CT scan (CAT scan): Hanya ce da ke yin jerin hotuna dalla-dalla na ciki, an ɗauke su daga kusurwa daban-daban. Ana yin hotunan ne ta wata kwamfuta da aka haɗa ta da na'urar da ke ɗauke da x-ray. Ana iya yin allurar fenti a cikin jijiya ko haɗiye don taimakawa gabobin ko kyallen takarda su fito fili karara. Wannan hanya ana kiranta yanayin ƙididdigar lissafi, ƙirar kwamfuta, ko ƙirar ƙwaƙwalwar ajiyar kwamfuta.

Babu daidaitaccen tsarin tsarkewa don girma AML.

An bayyana cutar a matsayin wacce ba a warke ta ba, a cikin gushewa, ko maimaituwa.

Balagagge mara girma AML

A cikin AML da ba a kula da shi ba, an gano sabon cutar. Ba a kula da shi ba sai don sauƙaƙe alamomi da alamomi kamar zazzaɓi, zubar jini, ko ciwo, kuma waɗannan gaskiya ne:

• Cikakken adadin jini ba al'ada bane.

• Akalla kashi 20 cikin dari na kwayoyin halittar da ke cikin kashin jini sune fashewa (kwayoyin cutar sankarar bargo).

• Akwai alamu ko alamomin cutar sankarar bargo.

Babban AML a cikin gafartawa

A cikin girma AML a cikin gafartawa, cutar ta bi da kuma waɗannan masu gaskiya ne:

• Cikakken adadin jini na al'ada ne.

• Kasa da kashi 5% na kwayoyin halittar da ke cikin kashin kasusuwa sune fashewa (kwayoyin cutar sankarar bargo).

• Babu alamu ko alamomin cutar sankarar bargo a cikin kwakwalwa da laka ko wani wuri a cikin jiki.

Maimaitawa Adult AML

Maimaita AML shine ciwon daji wanda ya sake dawowa (dawo) bayan an warke shi. AML na iya dawowa cikin jini ko ɓarna.

Bayanin Zaɓin Jiyya

MAGANAN MAGANA

• Akwai nau'ikan magani daban-daban ga marasa lafiya da ke fama da cutar sankarar myeloid mai girma.
• Kulawar manya AML galibi yana da matakai 2.
• Ana amfani da nau'i hudu na daidaitaccen magani:

• Chemotherapy

• Radiation far

• Chemotherapy tare da dasawa da kwayar halitta

• Sauran maganin magani

• Ana gwada sababbin nau'ikan magani a gwajin asibiti.

• Ciwon da aka yi niyya

• Jiyya don cutar sankaran myeloid na manya na iya haifar da illa.

• Marasa lafiya na iya son yin tunani game da shiga cikin gwaji na asibiti.

• Marasa lafiya na iya shiga gwajin asibiti kafin, lokacin, ko bayan fara maganin cutar kansa.

• Ana iya buƙatar gwaje-gwaje na gaba.

Akwai nau'ikan magani daban-daban ga marasa lafiya da ke fama da cutar sankarar myeloid mai girma.

Akwai nau'ikan magani daban-daban ga marasa lafiya masu fama da cutar sankarar bargo (AML) mai saurin girma. Wasu jiyya suna daidaito (magani da ake amfani dashi yanzu), kuma wasu ana gwada su a gwajin asibiti. Gwajin gwajin magani shine binciken bincike wanda aka tsara don taimakawa inganta ingantattun jiyya na yanzu ko samun bayanai game da sababbin jiyya ga marasa lafiya da ciwon daji. Lokacin da gwaji na asibiti ya nuna cewa sabon magani ya fi magani na yau da kullun, sabon magani na iya zama daidaitaccen magani. Marasa lafiya na iya son yin tunani game da shiga cikin gwaji na asibiti. Wasu gwaji na asibiti ana buɗe su ne kawai ga marasa lafiyar da basu fara magani ba.

Kulawar manya AML galibi yana da matakai 2.

Hanyoyin magani na 2 na manya AML sune:

• Magungunan shigar da hankali mai gafara: Wannan shine farkon lokacin magani. Burin shine a kashe kwayoyin cutar sankarar bargo a cikin jini da kashin kashi. Wannan ya sanya cutar sankarar bargo cikin gafara.

• Bayanin gafarawa: Wannan shine kashi na biyu na magani. Yana farawa ne bayan cutar sankarar bargo ta kasance cikin gafara. Makasudin magani bayan an gafarta masa shine a kashe sauran ƙwayoyin cutar sankarar jini wanda ba zai iya aiki ba amma zai iya fara sakewa da haifar da sake dawowa. Wannan lokaci ana kiransa farfadowa na ci gaba da gafara.

Ana amfani da nau'i hudu na daidaitaccen magani:

Chemotherapy

Chemotherapy magani ne na cutar kansa wanda ke amfani da magunguna don dakatar da haɓakar ƙwayoyin kansa, ko dai ta hanyar kashe ƙwayoyin ko ta hana su rarraba. Lokacin da ake shan chemotherapy ta baki ko allura a cikin jijiya ko tsoka, magungunan suna shiga cikin jini kuma zasu iya kaiwa ga kwayoyin cutar kansa a cikin jiki duka (chemotherapy systemic). Lokacin da aka sanya chemotherapy kai tsaye zuwa cikin ruwa mai ruɓaɓɓen ciki (intrathecal chemotherapy), wani sashin jiki, ko rami na jiki kamar ciki, magungunan yawanci suna shafar ƙwayoyin kansa a waɗancan yankuna (chemotherapy na yanki). Intrathecal chemotherapy za a iya amfani dashi don kula da AML mai girma wanda ya bazu zuwa kwakwalwa da laka. Haɗaɗɗiyar cutar sanadiyyar magani magani ne ta amfani da fiye da ɗaya maganin ƙwayar cutar kansa.

Hanyar da ake ba da cutar sankara ta dogara da ƙaramin nau'in AML da ake kula da shi kuma ko ƙwayoyin cutar sankarar bargo sun bazu zuwa cikin kwakwalwa da lakar kashin baya.

Intrathecal chemotherapy. Magungunan anticancer ana allurarsu a cikin sararin samaniya, wanda shine sararin da ke riƙe da ruwan sanyin jiki (CSF, wanda aka nuna a shuɗi). Akwai hanyoyi daban-daban guda biyu don yin wannan. Wata hanya, da aka nuna a saman ɓangaren adadi, ita ce a yi amfani da allurar ƙwayoyin a cikin wani tafki na Ommaya (akwati mai kama da dome wanda aka sanya shi a ƙarƙashin fatar kan mutum yayin aikin tiyata; yana riƙe da magungunan yayin da suke shiga ta cikin ƙaramin bututu zuwa cikin kwakwalwa ). Wata hanyar, wanda aka nuna a cikin ɓangaren ƙasa na adadi, shine a yi allurar ƙwayoyi kai tsaye zuwa CSF a cikin ƙananan ɓangaren kashin baya, bayan an lasafta wani ƙaramin yanki a ƙasan baya.

Dubi Magungunan da aka Amince da Ciwon Cutar Myeloid Mai Ciwo don ƙarin bayani.

Radiation far

Radiation therapy magani ne na cutar kansa wanda yake amfani da hasken rana mai ƙarfi ko wasu nau'ikan radiation don kashe ƙwayoyin kansa ko hana su girma. Akwai nau'o'in maganin radiation guda biyu:

• Magungunan radiation na waje yana amfani da inji a waje don aika radiation zuwa ga cutar kansa.

• Magungunan radiation na ciki yana amfani da abu mai tasirin rediyo wanda aka rufe a cikin allurai, tsaba, wayoyi, ko catheters waɗanda aka sanya kai tsaye zuwa ko kusa da ciwon daji.

Hanyar da ake ba da maganin raɗaɗɗen ya dogara da nau'in kansar da ake kula da shi kuma ko ƙwayoyin cutar sankarar bargo sun bazu zuwa cikin kwakwalwa da laka. Ana amfani da magungunan fitila na waje don kula da AML mai girma.

Chemotherapy tare da dasawa da kwayar halitta

Ana ba da magani don kashe ƙwayoyin kansa. Kwayoyin lafiya, gami da ƙwayoyin halitta masu jini, suma ana lalata su ta hanyar maganin kansa. Dasawar sel shine magani don maye gurbin kwayoyin halitta. Ana cire ƙwayoyin sari (ƙwayoyin jinin da basu balaga ba) daga cikin jinin ko ƙashin ƙashin mara lafiya ko mai bayarwa kuma ana daskarar dasu ana adana su. Bayan mai haƙuri ya gama shan magani, sai a narke ƙwayoyin ƙwayoyin da aka adana kuma a mayar da su ga mai haƙuri ta hanyar jiko. Waɗannan ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin na ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin na ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin na ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin na ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin magungunan za a ɗibar

Dasawar dasa kara (Mataki na 1): Ana ɗaukar jini daga jijiya a hannun mai bayarwa. Mai haƙuri ko wani mutum na iya zama mai ba da gudummawa. Jinin yana gudana ta cikin injin da ke cire ƙwayoyin sel. Sannan jinin yana dawowa ga mai bayarwa ta wata jijiya a daya hannun. (Mataki 2): Mai haƙuri yana karɓar magani don kashe ƙwayoyin halitta. Mai haƙuri na iya karɓar maganin radiation (ba a nuna ba). (Mataki na 3): Mai haƙuri yana karɓar ƙwayoyin sel ta hanyar catheter da aka sanya a cikin jijiyoyin jini a cikin kirji.

Sauran maganin magani

Arsenic trioxide da all-trans retinoic acid (ATRA) magunguna ne masu kashe kansa wanda ke kashe kwayoyin cutar sankarar bargo, dakatar da cutar sankarar jini daga rarrabawa, ko taimaka wa kwayoyin cutar sankarar jini su zama fararen jini. Ana amfani da waɗannan magungunan don maganin wani nau'in nau'in AML wanda ake kira sankarar promyelocytic leukemia.

Dubi Magungunan da aka Amince da Ciwon Cutar Myeloid Mai Ciwo don ƙarin bayani.

Ana gwada sababbin nau'ikan magani a gwajin asibiti.

Wannan ɓangaren taƙaitaccen bayani yana bayanin jiyya waɗanda ake nazarin su a gwajin asibiti. Yana iya ba ambaci kowane sabon magani ana nazarin. Ana samun bayani game da gwaji na asibiti daga gidan yanar gizon NCI.

Ciwon da aka yi niyya

Targeted therapy wani nau'in magani ne wanda yake amfani da magunguna ko wasu abubuwa don ganowa da afkawa takamaiman ƙwayoyin cutar kansa ba tare da cutar ƙwayoyin halitta ba. Magungunan rigakafi na Monoclonal shine ɗayan maganin warkewa da ake niyya akan karatun AML.

Magungunan antibody na Monoclonal magani ne na ciwon daji wanda ke amfani da kwayar cutar da aka yi a cikin dakin gwaje-gwaje daga nau'in kwayar halitta guda ɗaya. Wadannan kwayoyin cuta na jikin mutum na iya gano abubuwan da ke jikin kwayoyin cutar kansar ko kuma wasu abubuwa na yau da kullun wadanda zasu iya taimakawa kwayoyin cutar kansa. Kwayoyin rigakafin suna haɗuwa da abubuwan kuma suna kashe ƙwayoyin cutar kansa, toshe haɓakar su, ko kiyaye su daga yaɗuwa. Ana ba da ƙwayoyin cuta na Monoclonal ta hanyar jiko. Ana iya amfani da su su kaɗai ko ɗaukar ƙwayoyi, gubobi, ko kayan aikin rediyo kai tsaye zuwa ƙwayoyin kansa.

Jiyya don cutar sankaran myeloid na manya na iya haifar da illa.

Don bayani game da illolin da cutar ta kansar ta haifar, duba shafin mu na Side Side.

Marasa lafiya na iya son yin tunani game da shiga cikin gwaji na asibiti.

Ga wasu marasa lafiya, shiga cikin gwaji na asibiti na iya zama mafi kyawun zaɓin magani. Gwajin gwaji wani bangare ne na aikin binciken cutar kansa. Ana yin gwaje-gwajen asibiti don gano ko sabbin maganin cutar daji suna da lafiya da tasiri ko kuma sun fi magani na yau da kullun.

Yawancin yau da kullun na yau da kullun don cutar kansa sun dogara ne akan gwajin asibiti na farko. Marasa lafiya da ke cikin gwaji na asibiti na iya karɓar daidaitaccen magani ko kuma su kasance cikin farkon waɗanda za su karɓi sabon magani.

Marasa lafiya da ke shiga cikin gwaji na asibiti suma suna taimakawa inganta hanyar da za a bi da kansar a nan gaba. Koda lokacin gwajin asibiti bai haifar da sababbin magunguna ba, sau da yawa sukan amsa mahimman tambayoyi kuma suna taimakawa ci gaba da bincike gaba.

Marasa lafiya na iya shiga gwajin asibiti kafin, lokacin, ko bayan fara maganin cutar kansa.

Wasu gwaji na asibiti kawai sun haɗa da marasa lafiya waɗanda ba su sami magani ba tukuna. Sauran gwaje-gwajen suna gwada jiyya ga marasa lafiya waɗanda cutar kansa ba ta samu sauki ba. Hakanan akwai gwaji na asibiti da ke gwada sabbin hanyoyin dakatar da cutar kansa daga sake dawowa (dawowa) ko rage tasirin maganin kansar.

Gwajin gwaji na gudana a sassa da yawa na ƙasar. Bayani game da gwajin asibiti wanda NCI ke tallafawa ana iya samun shi akan shafin binciken gwaji na NCI. Ana iya samun gwajin gwaji na asibiti wanda wasu kungiyoyi ke tallafawa akan gidan yanar gizon ClinicalTrials.gov.

Ana iya buƙatar gwaje-gwaje na gaba.

Za a iya maimaita wasu gwaje-gwajen da aka yi don gano cutar kansa ko don gano matakin cutar kansa. Za a maimaita wasu gwaje-gwaje don ganin yadda magani ke aiki. Shawarwari game da ci gaba, canji, ko dakatar da magani na iya dogara ne da sakamakon waɗannan gwaje-gwajen.

Wasu daga cikin gwaje-gwajen za a ci gaba da yi daga lokaci zuwa lokaci bayan an gama jiyya. Sakamakon waɗannan gwaje-gwajen na iya nuna idan yanayin ku ya canza ko kuma idan kansar ta sake dawowa (dawo). Wadannan gwaje-gwajen wasu lokuta ana kiran su gwaje-gwaje na gaba ko dubawa.

Zaɓuɓɓukan Jiyya don Ciwon Cutar Myeloid Mai Girma na Matasa

A Wannan Sashin

• Babban Likitan Cutar Myeloid Mai Ciwon Cutar

• Babban Ciwon Cutar Myeloid mai Ciwo a Gaggawa

• Maidawan Ciwon Cutar Myeloid Mai Ciwo

Don bayani game da jiyya da aka jera a ƙasa, duba sashin Kula da Zaɓin Jiyya.

Babban Likitan Cutar Myeloid Mai Ciwon Cutar

Ingantaccen magani na cutar sankarar myeloid mai saurin girma (AML) yayin lokacin shigar da gafara ya dogara da nau'in AML kuma zai iya haɗa da masu zuwa:

• Hade chemotherapy.

• Babban magani mai hade da magani.

• -Ananan maganin ƙwayar cuta.

• Intrathecal chemotherapy.

• Duk-trans retinoic acid (ATRA) tare da arsenic trioxide don maganin mummunan cutar sankarar bargo (APL).

• ATRA da hadewar chemotherapy tare da arsenic trioxide don maganin APL.

Yi amfani da binciken bincikenmu na asibiti don nemo NCI na goyan bayan gwajin asibiti wanda ke karɓar marasa lafiya. Kuna iya bincika gwaji dangane da nau'in ciwon daji, shekarun mai haƙuri, da kuma inda ake yin gwajin. Ana samun cikakken bayani game da gwaji na asibiti.

Babban Ciwon Cutar Myeloid mai Ciwo a Gaggawa

Jiyya na AML na girma yayin lokacin gafartawa ya dogara da ƙaramin nau'in AML kuma yana iya haɗawa da masu zuwa:

• Hade chemotherapy.

• Chemaramin magani mai ƙarfi, tare da ko ba tare da maganin radiation ba, da kuma dasawa ta kwayar halitta ta amfani da ƙwayoyin sel na mai haƙuri.

• -Aramar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ta jiki ta amfani da ƙwayoyin ƙwayoyin cuta.

• Gwajin gwaji na arsenic trioxide.

Yi amfani da binciken bincikenmu na asibiti don nemo NCI na goyan bayan gwajin asibiti wanda ke karɓar marasa lafiya. Kuna iya bincika gwaji dangane da nau'in ciwon daji, shekarun mai haƙuri, da kuma inda ake yin gwajin. Ana samun cikakken bayani game da gwaji na asibiti.

Maidawan Ciwon Cutar Myeloid Mai Ciwo

Babu daidaitaccen magani ga mai girma AML. Jiyya ya dogara da ƙaramin nau'in AML kuma yana iya haɗawa da masu zuwa:

• Hade chemotherapy.

• Farfaɗar da aka yi niyya tare da ƙwayoyin cuta na monoclonal.

• Tsarin daskararren kwayar halitta ta amfani da sel na masu haƙuri ko kuma sel masu bada agaji.

• Arsenic trioxide far.

• Gwajin gwaji na maganin arsenic trioxide wanda ya biyo bayan dasawar sel.

Yi amfani da binciken bincikenmu na asibiti don nemo NCI na goyan bayan gwajin asibiti wanda ke karɓar marasa lafiya. Kuna iya bincika gwaji dangane da nau'in ciwon daji, shekarun mai haƙuri, da kuma inda ake yin gwajin. Ana samun cikakken bayani game da gwaji na asibiti.

Don ƙarin koyo game da Ciwon Cutar Myeloid na Ciwon Cutar sankarar Mutu

Don ƙarin bayani daga Cibiyar Cancer ta aboutasa game da cutar sankarar myeloid mai saurin girma, duba mai zuwa:

• Shafin Farko na cutar sankarar bargo

• An Amince da Magunguna don Ciwon Cutar Myeloid Mai Ciwo

• Tattara Kwayoyin Halitta mai Yin jini

• Magungunan Ciwon Cutar da Aka Yi niyya

Don cikakkun bayanai game da cutar kansa da sauran albarkatu daga Cibiyar Cancer ta Kasa, duba mai zuwa:

• Game da Ciwon daji

• Tsayawa

• Chemotherapy da ku: Tallafi ga Mutanen da ke Ciwon daji

• Radiation Far da Kai: Taimako ga Mutane Tare da Ciwon daji

• Yin fama da Ciwon daji

• Tambayoyi don Tambayar Doctor game da Ciwon daji

• Don Tsira da Kulawa