Types/brain/patient/child-glioma-treatment-pdq

Maganin ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar yara na yara (®) –Patient Version

Janar Bayani Game da Brawararriyar inwallon Childhoodwararriyar Childhoodwararru Glioma

MAGANAN MAGANA

• Brainwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar cuta wata cuta ce wacce ƙwayoyin cuta masu saurin ciwo (marasa cutar kansa) ko ƙananan ƙwayoyin cuta (keɓaɓɓu) ke samarwa a cikin ƙwanƙolin ƙwaƙwalwar ƙwaƙwalwar.

• Akwai gliomas na kwakwalwa guda biyu a cikin yara.

• Ba a san musabbabin mafi yawan cututtukan ƙwaƙwalwar yara ba.

• Alamu da alamomin bayyanar cututtukan kwakwalwa ba ɗaya bane a kowane ɗa.

• Ana amfani da gwaje-gwajen da ke bincika kwakwalwa don ganowa (samo) ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar yara.

• Ana iya yin biopsy don tantance wasu nau'ikan ƙwaƙwalwar ƙwaƙwalwar ajiyar ƙwaƙwalwa.

• Wasu dalilai suna shafar hangen nesa (damar dawowa).

Brainwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar cuta wata cuta ce wacce ƙwayoyin cuta masu saurin ciwo (marasa cutar kansa) ko ƙananan ƙwayoyin cuta (keɓaɓɓu) ke samarwa a cikin ƙwanƙolin ƙwaƙwalwar ƙwaƙwalwar.

Gliomas sune ciwace-ciwacen da aka samo daga ƙwayoyin glial. Kwayoyin Glial a cikin kwakwalwa suna riƙe da ƙwayoyin jijiyoyi a wurin, suna kawo abinci da oxygen cikin ƙwayoyin jijiyoyin, kuma suna taimakawa kare ƙwayoyin jijiyoyin daga cuta, kamar kamuwa da cuta. A cikin glioma na ƙwaƙwalwar ƙwaƙwalwar, ƙwayoyin jijiyoyin da ke cikin ƙwaƙwalwar ta shafi.

Kwakwalwar kwakwalwa ta kasance daga tsakiyar kwakwalwa, pons, da medulla. Wannan shine mafi ƙarancin ɓangaren kwakwalwa kuma yana haɗuwa da lakar kashin baya, sama da bayan wuyanta. Stemwaƙwalwar ƙwaƙwalwa tana sarrafa mahimman ayyuka kamar numfashi, bugun zuciya, da hawan jini, da jijiyoyi da tsokoki da ake amfani da su wurin gani, ji, tafiya, magana, da cin abinci.

Yawancin yawancin ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar yara sune yaduwar kwayar halitta (DIPG), wanda ke samuwa a cikin pons. Gliomas na focal a cikin sauran sassan kwakwalwa.

Anatomy na kwakwalwa. Yankin supratentorial (sashin sama na kwakwalwa) yana dauke da sinadarin kwakwalwa, na gefe da kuma na uku (tare da sinadarin cerebrospinal wanda aka nuna a shudi), choroid plexus, pineal gland, hypothalamus, pituitary gland, da jijiyoyin gani. Yankin fossa / infratentorial (ƙananan ɓangaren kwakwalwa) ya ƙunshi cerebellum, tectum, ventricle na huɗu, da ƙwanƙolin kwakwalwa (tsakiyar kwakwalwa, pons, da medulla). Gidan dakatarwa ya raba supratentorium daga infratentorium (dama panel). Kokon kai da meninges suna kare kwakwalwa da laka (bangaren hagu).

Ciwon ƙwaƙwalwa shine na biyu mafi yawan cututtukan daji a cikin yara.

Wannan taƙaitaccen bayani ne game da maganin cututtukan ƙwaƙwalwa na farko (ciwace-ciwacen da ke farawa a cikin kwakwalwa). Ba a tattauna game da jiyya game da cututtukan ƙwaƙwalwar ƙwaƙwalwa, waɗanda ciwace-ciwacen ƙwayoyin ƙwayoyin cuta ne waɗanda ke farawa daga wasu ɓangarorin jiki kuma suke yaɗuwa zuwa kwakwalwa, ba a tattauna shi a cikin wannan taƙaitaccen bayani.

Ciwon ƙwaƙwalwa na iya faruwa a cikin yara da manya; duk da haka, magani ga yara na iya zama daban da na manya. Don bayani game da maganin cututtukan ƙwaƙwalwa a cikin manya, duba Takaitaccen Treatmentarfin Ciwan umwayar Tsarin Ciwon Adwararru na ultarshe.

Akwai gliomas na kwakwalwa guda biyu a cikin yara.

Kodayake DIPG da kwakwalwar kwakwalwa suna haifar da glioma a cikin nau'in kwayar halitta, suna yin abubuwa daban:

• DIPG . DIPG shine ƙari mai saurin girma wanda ke samarwa a cikin ramin pons. DIPG yana da wuyar magani kuma yana da mummunan hangen nesa (damar dawowa) saboda mai zuwa:

• Ba cuta ce mai ma'ana ba kuma tana yaduwa tsakanin ƙwayoyin lafiya a cikin ƙwaƙwalwar ƙwaƙwalwa.

• Zai iya shafar ayyuka masu mahimmanci, kamar numfashi da bugun zuciya.

• Ocwayar ƙwaƙwalwa tana haifar da glioma. Glioma mai mahimmanci shine ƙari mai saurin girma wanda ke samarwa a waje da pons kuma a yanki ɗaya kawai na ƙwaƙwalwar kwakwalwa. Yana da sauƙin magani kuma yana da kyakkyawan hangen nesa fiye da DIPG.

Ba a san musabbabin mafi yawan cututtukan ƙwaƙwalwar yara ba.

Duk wani abu da zai kara maka hadarin kamuwa da cuta to ana kiran sa mai hadari. Samun haɗari ba ya nufin cewa za ku kamu da cutar kansa; ba tare da haɗarin abubuwan haɗari ba yana nufin cewa ba zaku sami cutar kansa ba. Yi magana da likitan ɗanka idan kana tunanin ɗanka na cikin haɗari. Abubuwan da ke iya haifar da haɗarin ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ciki sun haɗa da:

• Samun wasu cututtukan kwayoyin, kamar su neurofibromatosis type 1 (NF1).

Alamu da alamomin bayyanar cututtukan kwakwalwa ba ɗaya bane a kowane ɗa.

Alamomi da cututtuka sun dogara da masu zuwa:

• Inda ciwace ciwone yake yi a kwakwalwa.

• Girman kumburin da kuma yadda ya bazu a cikin kwakwalwar kwakwalwa.

• Yaya saurin ciwon ƙari.

• Shekarun yaron da matsayin ci gabansa.

Alamomi da alamomin na iya haifar da cutar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar yara ko ta wasu yanayi. Binciki likitan ɗanka idan ɗanka yana da ɗayan masu zuwa:

• Matsala tare da motsawar ido (ana juyar da ido ciki).

• Matsalar hangen nesa.

• Ciwon kai na safe ko ciwon kai wanda yake tafiya bayan amai.

• Tashin zuciya da amai.

• Baccin da ba'a saba ba.

• Rasa ikon motsa gefe guda na fuska ko jiki.

• Rashin daidaituwa da wahalar tafiya.

• Orara ko energyasa da ƙarfi fiye da yadda aka saba.

• Canje-canje a cikin hali.

• Matsalar koyo a makaranta.

Ana amfani da gwaje-gwajen da ke bincika kwakwalwa don ganowa (samo) ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar yara.

Za a iya amfani da waɗannan gwaje-gwajen da hanyoyin:

• Jarabawa ta jiki da tarihin lafiya: Jarabawa ta jiki don bincika alamomin lafiya gaba ɗaya, gami da bincika alamun cuta, kamar kumburi ko wani abu da kamar baƙon abu. Za a kuma ɗauki tarihin al'adun lafiyar marasa lafiya da cututtukan da suka gabata da magunguna.

• Nazarin ilimin lissafi: Jerin tambayoyi da gwaje-gwaje don bincika kwakwalwa, laka, da aikin jijiya. Jarabawar tana bincikar halin tunanin mutum, daidaituwarsa, da ikon yin tafiya yadda ya kamata, da kuma yadda ƙarfin jijiyoyi, hankula, da abubuwan da suke nunawa ke aiki. Hakanan ana iya kiransa gwajin neuro ko gwajin neurologic.

• MRI (hoton maganadisu ) tare da gadolinium: Hanya ce da ke amfani da maganadisu, igiyar ruwa ta rediyo, da kuma kwamfuta don yin jerin hotuna dalla-dalla na wurare a cikin kwakwalwa. Wani sinadari da ake kira gadolinium ne a cikin jijiya. Gadolinium yana tattarawa a kusa da ƙwayoyin cutar kansa don haka sun ƙara haske a hoton. Wannan hanya ana kiranta kuma ana kiranta hoton maganadisu na maganadisu (NMRI).

Ana iya yin biopsy don tantance wasu nau'ikan ƙwaƙwalwar ƙwaƙwalwar ajiyar ƙwaƙwalwa.

Idan hoton MRI yayi kama da ƙari shine DIPG, yawanci ba a yin biopsy kuma ba a cire kumburin. Lokacin da sakamakon binciken MRI bai tabbata ba, ana iya yin biopsy.

Idan hoton MRI yayi kama da ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa, ana iya yin biopsy. An cire wani ɓangare na kwanyar kuma ana amfani da allura don cire samfurin ƙwayoyin ƙwaƙwalwar. Wani lokaci, allura tana jagorantar kwamfuta. Kwararren likitan kwalliya yana kallon naman a ƙarƙashin madubin likita don neman ƙwayoyin kansa. Idan aka sami ƙwayoyin kansa, likita zai cire ƙari kamar yadda zai yiwu a yayin aikin tiyata.

Craniotomy: Ana yin buɗa a cikin kwanyar kuma an cire wani ɓangare na kwanyar don nuna wani ɓangare na kwakwalwa.

Ana iya yin gwajin na gaba akan samfurin nama wanda aka cire yayin nazarin halittu ko aikin tiyata:

• Immunohistochemistry: Gwajin gwaje-gwaje wanda ke amfani da kwayoyin cuta don bincika wasu antigens (alamomi) a cikin samfurin jikin mai haƙuri. Magungunan rigakafi yawanci suna da alaƙa da enzyme ko fenti mai kyalli. Bayan kwayoyin sun kunshi wani takamaiman antigen a cikin samfurin, sai a kunna enzyme ko rini, sannan za a iya ganin antigen a karkashin wani madubin likita. Ana amfani da irin wannan gwajin don taimakawa wajen gano kansar da kuma taimakawa gaya ga wani nau'in cutar kansa daga wani nau'in cutar kansa.

Wasu dalilai suna shafar hangen nesa (damar dawowa).

Hannun yaron ya dogara da masu zuwa:

• Nau'in ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa (DIPG ko focicl glioma).

• Inda ake samun kumburi a kwakwalwa kuma idan ya bazu a cikin kwakwalwar kwakwalwa.

• Shekarun yaro a ganewar asali

• Yaya tsawon lokacin da yaron yake da alamun bayyanar kafin a gano shi.

• Shin ko yaron yana da yanayin da ake kira neurofibromatosis type 1.

• Ko akwai wani canji a cikin kwayar halittar H3 K27m.

• Ko dai an gano kumburin ko kuma ya sake dawowa (dawo).

Yawancin yara masu fama da cutar DIPG suna rayuwa ne ƙasa da watanni 18 bayan ganewar asali. Yaran da ke da mahimmin ciwan rayuwa galibi suna rayuwa fiye da shekaru 5.

Matakai na ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar yara

MAGANAN MAGANA

• Tsarin kula da cutar kansa ya dogara ne kan ko ciwon ya kasance a wani yanki na kwakwalwa ko kuma ya bazu ko'ina cikin kwakwalwa.

Tsarin kula da cutar kansa ya dogara ne kan ko ciwon ya kasance a wani yanki na kwakwalwa ko kuma ya bazu ko'ina cikin kwakwalwa.

Staging tsari ne da ake amfani dashi don gano yawan cutar kansa da kuma idan kansar ta bazu. Yana da mahimmanci a san matakin don shirya magani.

Babu wani tsarin daidaitaccen tsari don ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar yara. Jiyya ya dogara da masu zuwa:

• Ko kumburin sabo ne sabon abu ko maimaitawa (ya dawo bayan jiyya).

• Nau'in tumo (ko dai yaduwar kwayar halitta mai yaduwa ko kuma mai kulawa).

Lwayar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa na iya sake dawowa shekaru da yawa bayan fara jiyya. Ciwon zai iya dawowa cikin kwakwalwa ko kuma a wasu sassan ɓangaren jijiyoyin. Kafin a ba da maganin cutar kansa, za a iya yin gwajin hoto, a binciki jikin mutum, ko kuma a yi aikin tiyata don a tabbatar akwai kansar da kuma gano yawan cutar kansa.

Bayanin Zaɓin Jiyya

MAGANAN MAGANA

• Akwai nau'ikan magani daban-daban na yara masu fama da ƙwaƙwalwar ƙwaƙwalwar ajiya.

• Yaran da ke da ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa ya kamata ƙungiyar masu ba da sabis na kiwon lafiya waɗanda suka ƙware a jiyya su shirya maganin su

yara ƙwaƙwalwar ƙwaƙwalwa.

• Ana amfani da nau'i biyar na daidaitaccen magani:

• Tiyata

• Radiation far

• Chemotherapy

• Cerebrospinal ruwa karkatarwa

• Lura

• Ana gwada sababbin nau'ikan magani a gwajin asibiti.

• Ciwon da aka yi niyya

• Jiyya don ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar yara zai iya haifar da sakamako masu illa.

• Marasa lafiya na iya son yin tunani game da shiga cikin gwaji na asibiti.

• Marasa lafiya na iya shiga gwajin asibiti kafin, lokacin, ko bayan fara maganin cutar kansa.

• Ana iya buƙatar gwaje-gwaje na gaba.

Akwai nau'ikan magani daban-daban na yara masu fama da ƙwaƙwalwar ƙwaƙwalwar ajiya.

Akwai nau'ikan magani iri daban-daban ga yara masu fama da cutar ƙwaƙwalwar ƙwaƙwalwa. Wasu jiyya suna daidaito (magani da ake amfani dashi yanzu), kuma wasu ana gwada su a gwajin asibiti. Gwajin gwajin magani shine binciken bincike wanda aka tsara don taimakawa inganta ingantattun jiyya na yanzu ko samun bayanai game da sababbin jiyya ga marasa lafiya da ciwon daji. Lokacin da gwaji na asibiti ya nuna cewa sabon magani ya fi magani na yau da kullun, sabon magani na iya zama daidaitaccen magani.

Saboda cutar kansa a cikin yara ba safai ba, ya kamata a yi la'akari da shiga cikin gwajin asibiti. Wasu gwaji na asibiti ana buɗe su ne kawai ga marasa lafiyar da basu fara magani ba.

Yaran da ke da ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa ya kamata ƙungiyar masu ba da sabis na kiwon lafiya waɗanda suka kware a kan kula da cututtukan ƙwaƙwalwar yara.

Jiyya za ta kula da likitan ilimin likitan yara, likita wanda ya kware kan kula da yara masu cutar kansa. Masanin ilimin likitancin yara yana aiki tare da wasu masu ba da kula da lafiya na yara waɗanda ƙwararru ne wajen kula da yara da ciwan ƙwaƙwalwa kuma waɗanda suka ƙware a wasu fannonin magani. Wadannan na iya hada da kwararru masu zuwa:

• Likitan yara.

• Neurosurgeon.

• Neuropathologist.

• Rikicin yara oncologist.

• Neuro-oncologist

• Neurologist.

• Neuroradiologist.

• Masanin ilimin likita.

• Masanin ilimin psychologist.

• Gwanayen gyarawa.

• Ma'aikacin zamantakewa.

• Kwararren rayuwar yara.

Ana amfani da nau'i biyar na daidaitaccen magani:

Tiyata

Biopsy ko tiyata don cire DIPG yawanci ba a yin sa saboda masu zuwa:

• DIPG ba taro bane guda daya. Yana yaduwa tsakanin lafiyayyun ƙwayoyin kwakwalwa a cikin ƙwaƙwalwar ƙwaƙwalwa.

• Zai iya shafar ayyuka masu mahimmanci, kamar numfashi da bugun zuciya.

Ana iya amfani da biopsy don tantancewa ko tiyata don cire ƙwayar cuta don ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar yara.

Radiation far

Radiation therapy magani ne na cutar kansa wanda yake amfani da hasken rana mai ƙarfi ko wasu nau'ikan radiation don kashe ƙwayoyin kansa ko hana su girma. Akwai nau'o'in maganin radiation guda biyu:

• Magungunan radiation na waje yana amfani da inji a waje don aika radiation zuwa ga cutar kansa.

• Magungunan radiation na ciki yana amfani da abu mai tasirin rediyo wanda aka rufe a cikin allurai, tsaba, wayoyi, ko catheters waɗanda aka sanya kai tsaye zuwa ko kusa da ciwon daji.

Hanyar da ake ba da maganin taɗɗar radiation ya dogara da nau'in cutar kansa da ake kula da ita. Ana amfani da maganin radiation na waje don magance DIPG. Za a iya amfani da maganin taɓin ciki na waje da / ko na ciki don magance gliomas ƙwaƙwalwar ƙwaƙwalwar ajiya.

Watanni da yawa bayan farkewar radiation zuwa cikin kwakwalwa, gwajin hoto na iya nuna canje-canje ga ƙwayar kwakwalwa. Wadannan canje-canjen na iya haifar da su ta hanyar maganin fitila ko kuma yana iya nufin cewa ƙari yana girma. Yana da mahimmanci a tabbatar kumburin yana girma kafin a ba da wani magani.

Chemotherapy

Chemotherapy magani ne na cutar kansa wanda ke amfani da magunguna don dakatar da haɓakar ƙwayoyin kansa, ko dai ta hanyar kashe ƙwayoyin ko ta hana su rarraba. Lokacin da ake shan chemotherapy ta baki ko allura a cikin jijiya ko tsoka, magungunan suna shiga cikin jini kuma zasu iya kaiwa ga kwayoyin cutar kansa a cikin jiki duka (systemotherapy chemotherapy). Lokacin da aka sanya chemotherapy kai tsaye a cikin ruɓaɓɓen ruɓaɓɓen ciki, gaɓoɓi, ko rami na jiki kamar ciki, magungunan yawanci suna shafar ƙwayoyin cutar kansa a waɗancan yankuna (chemotherapy na yanki). Hanyar da ake ba da cutar sankara ta dogara da nau'in cutar sankara.

Saboda maganin fitila ga kwakwalwa na iya shafar girma da ci gaban kwakwalwa a cikin yara ƙanana, ana iya ba da magani don jinkirta ko rage buƙatar maganin fuka-fuka.

Cerebrospinal ruwa karkatarwa

Cerebrospinal fluid karkatarwa hanya ce da ake amfani da ita don fitar da ruwan da ya taso a cikin kwakwalwa. Ana sanya shunt (dogon, siraran sifa) a cikin ƙwararriya (cike da ruwa) na kwakwalwa kuma a liƙa shi ƙarƙashin fata zuwa wani ɓangare na jiki, yawanci ciki. Shunt yana ɗaukar ƙarin ruwa daga kwakwalwa don haka yana iya shafan wani wuri a cikin jiki.

Cerebrospinal fluid (CSF) karkatarwa. Removedarin CSF an cire shi daga cikin abin da ke cikin ƙwaƙwalwa ta hanyar shunt (bututu) kuma an wofeshi cikin ciki. Wani bawul ne yake sarrafa kwararar CSF.

Lura

Lura yana lura da yanayin mai haƙuri ba tare da ba da magani ba har sai alamu ko alamu sun bayyana ko canzawa.

Ana gwada sababbin nau'ikan magani a gwajin asibiti.

Wannan ɓangaren taƙaitaccen bayani yana bayanin jiyya waɗanda ake nazarin su a gwajin asibiti. Yana iya ba ambaci kowane sabon magani ana nazarin. Ana samun bayani game da gwaji na asibiti daga gidan yanar gizon NCI.

Ciwon da aka yi niyya

Targeted therapy wani nau'in magani ne wanda yake amfani da magunguna ko wasu abubuwa don ganowa da afkawa takamaiman ƙwayoyin cutar kansa ba tare da cutar ƙwayoyin halitta ba.

Akwai nau'ikan magani daban-daban da ake niyya don nazarin ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar kwakwalwa:

• Kinase inhibitor far ya toshe wasu sunadarai, kamar BRAF ko MEK, wanda na iya taimakawa kiyaye ƙwayoyin kansar daga girma ko rarrabuwa. Dabrafenib (BRAF kinase inhibitor) da trametinib (MEK kinase inhibitor) ana karantar dasu don kula da sabuwar cutar da aka gano da kuma yawan kwakwalwa.

• Tarihin maganin hana amfani na deacetylase (HDI) na iya dakatar da haɓakar ƙwayoyin tumo ta hana wasu enzymes da ake buƙata don haɓakar kwayar halitta. Hakanan nau'in wakili ne na angiogenesis. Ana nazarin Panobinostat a cikin maganin DIPG wanda bai amsa magani ba ko sake dawowa.

• Magungunan antibody na Monoclonal yana amfani da kwayar cutar da aka sanya a dakin gwaje-gwaje daga nau'in kwayar halitta guda ɗaya. Wadannan kwayoyin cuta na jikin mutum na iya gano abubuwan da ke jikin kwayoyin cutar kansar ko kuma wasu abubuwa na yau da kullun wadanda zasu iya taimakawa kwayoyin cutar kansa. Kwayoyin rigakafin suna haɗuwa da abubuwan kuma suna kashe ƙwayoyin cutar kansa, toshe haɓakar su, ko kiyaye su daga yaɗuwa.

Kwayar cuta ta monoclonal, APX005M, tana ɗaura da CD40, mai karɓar farfajiyar ƙwayar salula da aka samo akan wasu ƙwayoyin ƙwayoyin cuta da wasu ƙwayoyin kansa. Yana iya yaƙi da cutar kansa ta hanyar haɓaka garkuwar jiki da kuma rage saurin kwayar cutar kansa. Ana yin nazarin ne game da maganin cututtukan ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar yara waɗanda suke girma, faɗaɗa, ko ƙara munana (ci gaba), ko kuma a cikin sabon binciken DIPG.

Jiyya don ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar yara zai iya haifar da sakamako masu illa.

Don bayani game da illolin da ke farawa yayin magani don cutar kansa, duba shafin Gurbinmu.

Hanyoyi masu illa daga maganin ciwon daji wanda zai fara bayan jiyya kuma ya ci gaba tsawon watanni ko shekaru ana kiransa sakamako na ƙarshe. Effectsarshen sakamako na iya haɗawa da masu zuwa:

• Matsalolin jiki.

• Canje-canje a cikin yanayi, ji, tunani, ilmantarwa, ko ƙwaƙwalwar ajiya.

• Cancer na biyu (sababbin nau'ikan cutar kansa).

Wasu maganganun ƙarshen ana iya magance su ko sarrafa su. Yana da mahimmanci a yi magana da likitocin ɗanka game da illar da cutar kansa za ta iya yi wa ɗanka. (Dubi taƙaitaccen bayanin akan ƙarshen tasirin Jiyya don Ciwon Childhoodan yara don ƙarin bayani).

Marasa lafiya na iya son yin tunani game da shiga cikin gwaji na asibiti.

Ana samun bayani game da gwaji na asibiti daga gidan yanar gizon NCI.

Ga wasu marasa lafiya, shiga cikin gwaji na asibiti na iya zama mafi kyawun zaɓin magani. Gwajin gwaji wani bangare ne na aikin binciken cutar kansa. Ana yin gwaje-gwajen asibiti don gano ko sabbin maganin cutar daji suna da lafiya da tasiri ko kuma sun fi magani na yau da kullun.

Yawancin yau da kullun na yau da kullun don cutar kansa sun dogara ne akan gwajin asibiti na farko. Marasa lafiya da ke cikin gwaji na asibiti na iya karɓar daidaitaccen magani ko kuma su kasance cikin farkon waɗanda za su karɓi sabon magani.

Marasa lafiya da ke shiga cikin gwaji na asibiti suma suna taimakawa inganta hanyar da za a bi da kansar a nan gaba. Koda lokacin gwajin asibiti bai haifar da sababbin magunguna ba, sau da yawa sukan amsa mahimman tambayoyi kuma suna taimakawa ci gaba da bincike gaba.

Marasa lafiya na iya shiga gwajin asibiti kafin, lokacin, ko bayan fara maganin cutar kansa.

Wasu gwaji na asibiti kawai sun haɗa da marasa lafiya waɗanda ba su sami magani ba tukuna. Sauran gwaje-gwajen suna gwada jiyya ga marasa lafiya waɗanda cutar kansa ba ta samu sauki ba. Hakanan akwai gwaji na asibiti da ke gwada sabbin hanyoyin dakatar da cutar kansa daga sake dawowa (dawowa) ko rage tasirin maganin kansar.

Gwajin gwaji na gudana a sassa da yawa na ƙasar. Bayani game da gwajin asibiti wanda NCI ke tallafawa ana iya samun shi akan shafin binciken gwaji na NCI. Ana iya samun gwajin gwaji na asibiti wanda wasu kungiyoyi ke tallafawa akan gidan yanar gizon ClinicalTrials.gov.

Ana iya buƙatar gwaje-gwaje na gaba.

Za a iya maimaita wasu gwaje-gwajen da aka yi don gano cutar kansa ko don gano matakin cutar kansa. Za a maimaita wasu gwaje-gwaje don ganin yadda magani ke aiki. Shawarwari game da ci gaba, canji, ko dakatar da magani na iya dogara ne da sakamakon waɗannan gwaje-gwajen.

Wasu daga cikin gwaje-gwajen za a ci gaba da yi daga lokaci zuwa lokaci bayan an gama jiyya. Sakamakon waɗannan gwaje-gwajen na iya nuna idan yanayin ɗanku ya canza ko kuma idan ciwon daji ya sake dawowa (dawo). Wadannan gwaje-gwajen wasu lokuta ana kiran su gwaje-gwaje na gaba ko dubawa.

Idan sakamakon gwajin hoto da aka yi bayan jiyya ga DIPG ya nuna ɗimbin yawa a cikin ƙwaƙwalwa, za a iya yin biopsy don gano ko ya kasance da ƙwayoyin marurai da suka mutu ko kuma idan sababbin ƙwayoyin daji suna girma. A cikin yaran da ake tsammanin zasu rayu na dogon lokaci, ana iya yin MRI na yau da kullun don ganin ko kansar ta dawo.

Jiyya na DIPG

Don bayani game da jiyya da aka jera a ƙasa, duba sashin Kula da Zaɓin Jiyya.

Sabon binciken yaduwar yarinta asalin kwayar cutar glioma (DIPG) shine ƙari wanda ba a ba da magani ba. Yaron na iya karɓar kwayoyi ko magani don taimakawa alamomi ko alamomin da ciwon kumburi ya haifar.

Ingantaccen magani na DIPG na iya haɗawa da masu zuwa:

• Ragewar radiation ta waje

• Chemotherapy (a cikin jarirai).

• Gwajin gwaji na sabon magani.

Jiyya na ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta ta Glioma

Sabon binciken ƙwayar yara glioma shine ƙari wanda ba a ba da magani ba. Yaron na iya karɓar kwayoyi ko magani don taimakawa alamomi ko alamomin da ciwon kumburi ya haifar.

Jiyya na glioma mai mahimmanci zai iya haɗa da masu zuwa:

• Yin aikin tiyata don cire kumburin na iya bi da chemotherapy da / ko magungunan fitila na waje.

• Lura don ƙananan ciwace-ciwacen da suke girma a hankali. Za'a iya karkatar da hanzarin mahaifa lokacin da akwai karin ruwa a cikin kwakwalwa.

• Magungunan radiation na ciki tare da ƙwayoyin rediyo, tare da ko ba tare da chemotherapy ba, lokacin da ba za a iya cire kumburin ta hanyar tiyata ba.

• Gwajin gwaji na asibiti da aka yi niyya tare da mai hana BRAF kinase (dabrafenib) haɗe tare da mai hana MEK (trametinib), don wasu ciwace-ciwacen da ba za a iya cire su ta hanyar tiyata ba.

Jiyya na ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa a cikin yara tare da nau'in 1 na neurofibromatosis na iya zama kallo. Ciwan daji suna girma a hankali cikin waɗannan yara kuma bazai buƙatar takamaiman magani na shekaru ba.

Jiyya na Ci Gaban Ciwon Childhoodwallon Childhoodwallon Childhoodananan yara Glioma

Lokacin da cutar daji ba ta inganta da magani ko ta dawo ba, kulawar kwantar da hankali wani muhimmin bangare ne na shirin kula da lafiyar yaro. Ya haɗa da tallafi na jiki, na ɗabi'a, na zaman jama'a, da na ruhaniya ga yaro da iyali. Manufar kulawa da jinƙai shine don taimakawa kula da alamomin kuma bawa yaro mafi kyawun rayuwa mai yiwuwa. Iyaye ba su da tabbas game da ci gaba da magani ko kuma wane irin magani ne mafi kyau ga ɗansu. Careungiyar kiwon lafiya na iya ba iyayen bayanai don taimaka musu yin waɗannan shawarwarin.

Za a iya ba wa yara da ke samun ci gaba ko kuma taɓarɓarewar ciki glioma (DIPG) waɗanda suka amsa lokacin da aka fara bi da su ta hanyar amfani da radiation. Jiyya na ci gaba ko maimaita DIPG na iya haɗawa da masu zuwa:

• Gwajin gwaji wanda ke bincikar samfurin ƙwayar cutar mai haƙuri don wasu canje-canje na asali. Nau'in maganin da aka yiwa niyya wanda za'a baiwa mai haƙuri ya dogara da nau'in canjin halittar mutum.

• Gwajin gwaji na maganin farfadowa tare da histone deacetylase inhibitor (panobinostat) ko kwayar cutar monoclonal (APX005M).

Jiyya na ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar yara zai iya haɗa da waɗannan masu zuwa:

• Tiyata ta biyu don cire kumburin.

• Ragewar radiation ta waje

• Chemotherapy.

• Gwajin gwaji wanda ke bincikar samfurin ƙwayar cutar mai haƙuri don wasu canje-canje na asali. Nau'in maganin da aka yiwa niyya wanda za'a baiwa mai haƙuri ya dogara da nau'in canjin halittar mutum.

Don Moreara Koyo Game da Tananan inwayoyin inwalwa

Don ƙarin bayani game da cututtukan ƙwaƙwalwar yara, duba masu zuwa:

• Consortium Brain Tumor Consortium (PBTC) Fita daga Sanarwa

• Sadarwa a Kula da Ciwon daji

• Shirya Canjin Tsarin Kula da Endarshen Rayuwa a Ciwon Cutar Canji

• Kulawa da Kulawa da Kula da Yara (Karshen Kula da Rayuwa)

Don ƙarin bayani game da cutar sankarar yara da sauran albarkatun kansar gaba ɗaya, duba masu zuwa:

• Game da Ciwon daji

• Ciwon Yara

• Binciken Cure don Ciwon Childrenan yara

• Matsayi na Late na Jiyya don Ciwon Yara

• Matasa da Samari da Ciwon daji

• Yara da Ciwon daji: Jagora ga Iyaye

• Ciwon daji a cikin Yara da Matasa

• Tsayawa

• Yin fama da Ciwon daji

• Tambayoyi don Tambayar Doctor game da Ciwon daji

• Don Tsira da Kulawa