Translations:Research/nci-role/spotlight/oia/21/en

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David Lyden, M.D., Ph.D.Exit Disclaimer
Title: Professor of Pediatrics
Institution: Weill Medical College of Cornell University
Research: Dr. Lyden will explore the possibility that inhibition of specific exosomal cargo or their targets in hematopoietic cells could reverse immunosuppression, pre-metastatic niche formation and the systemic effects of cancer. He will study the mechanisms through which exosome subpopulations and exomeres (the most prominent tumor-secreted particles) regulate immune system mobilization, metabolic changes and plasticity of pre-metastatic and metastatic niches in cancer models and patients.