Title: Professor and Chair, Department of Radiation Oncology
Institution: Perlmutter Cancer Center NYU Langone Medical CenterExit Disclaimer
Research: Kimmelman’s team has been studying how pancreatic ductal adenocarcinoma (PDAC) rewires the metabolism to proliferate and survive in nutrient poor microenvironments. Integration of PDAC’s metabolic adaptations and how they influence the tumor’s metabolism in vivo is not yet known. Kimmelman will use syngeneic models of pancreatic cancer to assess metabolic dependencies, use co-culture systems to identify metabolic cross-talk in the microenvironment and dissect nutrient scavenging pathways. From this information robust metabolic targets will be tested in vivo.
