Title: Director of the Institute for Cancer Outcomes and Survivorship
Institution: University of Alabama at Birmingham
Research: The two leading causes of premature mortality in childhood cancer survivors are radiation-related subsequent neoplasms (SNs) and anthracycline-related cardiac dysfunction (CD). Bhatia seeks to develop a risk prediction model for radiation-related SN and anthracycline-related CD in childhood cancer survivors, replicate the optimized model in an independent cohort of childhood cancer survivors, apply the model to newly-diagnosed children with cancer to predict the risk of incident SN/CD, and determine the functional relevance of the genetic signatures. Findings from this application will help reduce the burden of morbidity in this population.