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 h English (en)The return on investment from aggregating and sharing research data is particularly high for rare cancers, such as those that occur in children.
[[File:Sara-rothschild-and-becky-owens-at-15th-pediatric-and-wildtype-clinic-article.jpg|200px|thumb|right|NCI's Rare Clinics Fostering Collaboration]]
Mining the sheer volume of "big data" to answer the complex biological questions that will bring precision medicine into the mainstream of clinical care, however, remains a challenge. Nowhere is this challenge more evident than in oncology, as much of these data will come from studies of patients with cancer.