Difference between revisions of "Research/key-initiatives/ras/target-identification"
(Created page with "== RAS Target Identification at FNLCR == The RAS Initiative at the Frederick National Laboratory for Cancer Research (FNLCR) is using cutting edge technologies to better defi...") |
|||
| Line 1: | Line 1: | ||
| + | <languages/> | ||
| + | <translate> | ||
== RAS Target Identification at FNLCR == | == RAS Target Identification at FNLCR == | ||
| Line 18: | Line 20: | ||
This lab group develops tools to track and analyze “big data” from the RAS Initiative and the larger RAS community. | This lab group develops tools to track and analyze “big data” from the RAS Initiative and the larger RAS community. | ||
| + | </translate> | ||
Revision as of 20:46, 28 October 2019
Contents
RAS Target Identification at FNLCR
The RAS Initiative at the Frederick National Laboratory for Cancer Research (FNLCR) is using cutting edge technologies to better define RAS proteins, complexes of RAS proteins with effector and regulatory partners, cell surface proteins that are enriched in cancer cells driven by mutant RAS, and pathways that are essential to cancer cells but not normal cells.
RAS Reagents
Attacking cancers caused by mutant RAS requires proteins, DNAs, and cell lines prepared by this group.
RAS Structural Biology
This group aims to provide structural insights into oncogenic mutants of RAS, RAS-effector, and RAS-interactor complexes.
RAS Biochemistry and Biophysics
Signaling by RAS proteins is regulated by the interactions with substrates, protein partners, and membranes that are investigated by this lab.
RAS Informatics
This lab group develops tools to track and analyze “big data” from the RAS Initiative and the larger RAS community.
